ライフサイエンスコーパス: large excess

1 for concentrations of either H2O2 or ODI in large excess.

2 No reaction partner was used in large excess.

3 more pronounced when MAH is the reactant in large excess.

4 quired the substrate to be the solvent or in large excess.

5 ns containing various competitive cations in large excess.

6 For gas mixtures where NO is not in large excess, a mixed layer with (2x2) structure is form

7 Large excess addition of F(-) promotes deprotonation of

8 hly similar physical properties to H(2)O and large excess amounts of H(2)O over D(2)O, it is challeng

9 dine as the limiting reagent, as it required large excesses and high concentrations to achieve reason

10 crystals of the wild-type were grown with a large excess aspartate while the cross-linked crystals w

11 These results suggest that large excess capacities found in some biochemical and ph

12 Moreover, our data demonstrates there is a large excess capacity of liver ASGR for the effective up

13 The J-aggregation requires a large excess CMA concentration; the J-band maximum appea

14 ange the encoded amino acid, were found in a large excess compared to nonsilent sites among the editi

15 In the presence of a large excess concentration of metbox DNA, the effect of

16 tioned as a highly active DNase to destroy a large excess DNA substrate, which could provide a powerf

17 This large excess entropy is quenched by an in-plane magnetic

18 Interactions produce large excess free energy that dominate the properties of

19 A were observed when chlorine was present in large excess (HOCl/phenol ratios of 30:1 to 50:1), with

20 In the presence of oxygen in large excess, however, traditional three-way catalysts a

21 how tubular proteinuria can occur despite a large excess in potential proximal tubule uptake capacit

22 tubular proteinuria can occur even though a large excess in potential PT uptake capacity exists, and

23 Large excess mortality and high numbers of potential yea

24 ted catalytic domain after incubation with a large excess of 7, 8-dihydropterin, DTT, and Fe(2+).

25 Reacting [(Me(3)tacn)Mo(CN)(3)] with a large excess of [(cyclam)Ni(H(2)O)(2)](2+) produces a [(

26 for the detection of HZ in the presence of a large excess of a common active pharmaceutical ingredien

27 A large excess of a single-base mismatch oligonucleotide h

28 f larger DNA components in the presence of a large excess of a smaller DNA component or in a DNA mixt

29 fied protein by addition of a phosphine or a large excess of a thiol.

30 tion between adduct-containing sites and the large excess of adduct-free DNA distributed throughout t

31 tensity above coplated microglial cells or a large excess of albumin.

32 A large excess of ALDH3A1 also protected glucose-6-phospha

33 thod uses 2,2,2-trifluoroethanol (TFE) and a large excess of amine.

34 Control experiments employing a large excess of ammonia as a base indicate this new prop

35 ce catalyst degradation by the presence of a large excess of ammonia under the catalytic conditions.

36 d for activation and that is stable toward a large excess of ammonia.

37 phosphate (AMPPNP) promote ADP binding and a large excess of AMPPNP is required to displace ADP from

38 reaction conditions, and avoids the use of a large excess of an alcohol nucleophile.

39 In each case, there was a large excess of AT-->GC compared to GC-->AT mutations (r

40 palladacycle catalysts required the use of a large excess of benzoic anhydride (which is very difficu

41 ing protocols that use this enzyme require a large excess of both substrate and sortase to produce hi

42 electivity toward Con A in the presence of a large excess of bovine serum albumin (BSA).

43 e for human thrombin even in the presence of large excess of bovine thrombin, bovine serum albumin, c

44 proximity to each other in the presence of a large excess of buffer.

45 eased 2.5-2.7 fold after pretreatment with a large excess of C225.

46 enhancement is reduced by the addition of a large excess of Ca(II), indicating that these ions bind

47 t number of anionic charges, were added to a large excess of cationic surfactant (dodecyltrimethylamm

48 40-fold by a single-pass cell sorting from a large excess of cells expressing WT antibody with a slig

49 ow catalytic activities, poor tolerance to a large excess of chain transfer agent, and tendency to fo

50 nly moderate yields were obtained even for a large excess of chloranil, whereas high yields could be

51 In the presence of a large excess of Cl(-) ([I(-)] approximately 10 mM and [C

52 We detected the BSE prion protein within a large excess of classical, atypical, and CH1641 scrapie

53 working in the presence of added water and a large excess of CO2 (40 atm), in addition to CuCl2 and T

54 rB/Hg/DTT complex, even in the presence of a large excess of competing cysteine, has been demonstrate

55 a(Hg) reduction in acetonitrile containing a large excess of cryptand[2.2.2] exhibits a Hush-type int

56 sts that catalyst deactivation occurs with a large excess of cyanamide over longer reaction times.

57 ric, unspliced viral RNA in the context of a large excess of cytosolic human RNAs.

58 In the absence of CO2, the addition of a large excess of DBU to [(LCu)2H](+) results in an equili

59 to stromal feeder cells in the presence of a large excess of differentiated OE neurons.

60 The present method does not require a large excess of diols that can be valuable and does not

61 When a large excess of divalent metal ions is absent, the charg

62 When a large excess of divalent metal ions is present, the char

63 Addition of a large excess of DMS to the oxidised enzyme in solution c

64 n many species and explain, for example, the large excess of DSBs over crossovers and the repair of D

65 on of bacteriophage MS2 in the presence of a large excess of E. coli.

66 ion up to 10(-7) M, and of the addition of a large excess of EDTA.

67 generally exhibit high activity only with a large excess of electrolyte.

68 e of directing groups or the employment of a large excess of electronically activated arenes, typical

69 complex is formed even in the presence of a large excess of EnvZc, OmpR binding to EnvZc is co-opera

70 onditions where free template was present in large excess of enzyme.

71 is formed by the reaction of an amide with a large excess of ethyl isocyanate at elevated temperature

72 ersion of creatine to phosphocreatine with a large excess of exogenous ATP, conversion of all ATP to

73 e complemented for pyocyanin production by a large excess of exogenous N-butyryl homoserine lactone (

74 xtent where it cannot be prevented even by a large excess of external H-atom donor.

75 s, we show that what is now seen as normal-a large excess of female life expectancy in adulthood-is a

76 Spiroplasma infection continued to produce a large excess of female progeny, while females that had l

77 cess of males, among trisomy 18 live borns a large excess of females, and among trisomy 21 live borns

78 tor interaction in vitro was unaffected by a large excess of free activator protein, pointing to a dy

79 ctively than the beta2AR co-expressed with a large excess of G(s alpha).

80 These results indicate that, despite the large excess of genetic potential of the mammalian mitoc

81 ly specific for 5caC even in the presence of large excess of genomic DNA, a property that can potenti

82 In the presence of a large excess of H2O2, this intermediate rapidly decays w

83 allow HA synthesis even in the presence of a large excess of HA-degrading enzyme.

84 the observed mutation spectrum, which has a large excess of helical domain mutations.

85 thiol-stimulated ATPase activity, although a large excess of heme inhibited activity.

86 ies using palladium catalysis often employ a large excess of heterocycle substrates to overcome these

87 Thus, nitrite-loaded variant reduction by a large excess of hexaammineruthenium(II) yielded quantita

88 fied by NMR in the reaction of BH4(-) with a large excess of HN(NO2 )2 .

89 However, in the presence of a large excess of Hsc70, refolding of pmAAT is still arres

90 r cells were treated with hyaluronidase or a large excess of hyaluronan, indicating that hyaluronan o

91 When a large excess of imidazole is added to this five-coordina

92 he assay is carried out in the presence of a large excess of inactive variants of AATase.

93 me scales of the magnon system, results in a large excess of incoherent magnons.

94 However, the lysates also contain a large excess of infectious phage particles which complic

95 This suggests that the reported large excess of inverted repeats is due to repeats found

96 served upon treatment of siliconoid 5 with a large excess of iodine in refluxing toluene, thus provid

97 nd progress toward eliminating the requisite large excess of LiCl are discussed.

98 h these structures even in the presence of a large excess of linear duplex DNA.

99 their binding sites while confronted with a large excess of low-affinity degenerate motifs.

100 highly selective, even in the presence of a large excess of lysine, cysteine, and histidine.

101 low abundance of (236)U and the presence in large excess of major isotopes (mainly (238)U and (235)U

102 cancer (34 cases: SIR 2.41, 1.67-3.36) and a large excess of male breast cancer (five cases: SIR 15.0

103 requires cocrystallization of analyte with a large excess of matrix, which must be mutually soluble i

104 ng antagonistic SNPs functionally, we find a large excess of missense variants but little enrichment

105 n vitro solid MnOx formation when there is a large excess of Mn(II).

106 leation processes, even in the presence of a large excess of monomer.

107 r amyloid deposits even in the presence of a large excess of monomeric Abeta or its precursor.

108 or RA, this therapy is not associated with a large excess of mortality nor with an unusual spectrum o

109 We find that a large excess of muscle agrin failed to inhibit either th

110 Interestingly, coexpression of a large excess of N- or C-terminally deleted P with wild-t

111 This finding, in conjunction with the large excess of Na(+) in physiological environments, min

112 e functionally coupled to H(+), owing to the large excess of Na(+) in physiological settings.

113 e restored by reacting aqueous OXA-24 with a large excess of NaHCO(3), which recarboxylates Lys84.

114 ceedingly rare sites of damage embedded in a large excess of nearly identical undamaged DNA, while ca

115 ively remove TcO(4) (-) in the presence of a large excess of NO(3) (-) and SO(4) (2-) .

116 tion of (99) TcO(4) (-) in the presence of a large excess of NO(3) (-) and SO(4) (2-) from natural wa

117 response is insensitive to the presence of a large excess of non-complementary DNA sequences.

118 )C-labeled tracer is always accompanied by a large excess of non-radioactive tracer known as carrier.

119 that the identified de novo mutations show a large excess of non-synonymous changes in schizophrenia

120 ies of their RNA genomes in the context of a large excess of nongenomic RNA.

121 ates DNA annealing even in the presence of a large excess of nonhomologous DNA.

122 hose found in vivo, and in the presence of a large excess of nonspecific competitor DNA.

123 , with an effective discrimination against a large excess of nontarget proteins.

124 Under conditions of a large excess of ODI, the reaction is more than 1 order o

125 With a large excess of oil, diffusion was also limited, as only

126 obviates the need for directing groups or a large excess of one of the coupling partners.

127 mediated ligation is reversible, requiring a large excess of one of the ligation partners to shift th

128 lic and acyclic styrenes without requiring a large excess of one reactant, facilitated by the signifi

129 reagents, and does not require the use of a large excess of organometallic reagent.

130 heterocycles that compete favorably with the large excess of PC alkyl side-chains that make up the mi

131 Recent analyses have shown that there is a large excess of perfect inverted repeats in many prokary

132 D(50) and PMCAb(50) values could be due to a large excess of PMCAb-reactive prion protein seeds with

133 As prostatic epithelia produce a large excess of polyamines, the androgen-induced polyami

134 the sortase reaction reaches equilibrium, a large excess of polyglycine nucleophile is often employe

135 y identify functional mutations from among a large excess of polymorphisms, incidental mutations, and

136 Despite their importance and a large excess of precursors (i.e., DNA double-strand brea

137 , with extremely low genetic diversity and a large excess of rare polymorphisms.

138 ce proteins of interest in the presence of a large excess of relatively abundant proteins.

139 ored over monomeric interactions even when a large excess of saccharide was present.

140 the reductive elimination of F(2) requires a large excess of SbF(5) and occurs in the last reaction s

141 Finally, we find a large excess of singleton polymorphisms in the full data

142 ghly alkaline solutions containing extremely large excess of sodium cations as well as in acidic envi

143 In particular, materials presenting a large excess of soft elastic modes, the so-called boson

144 ecies at neutral pH and in the presence of a large excess of spectator ions.

145 roduct, rather than being intercepted by the large excess of starting propargyl alcohol.

146 There was a large excess of studies replicating the first positive r

147 of their gRNA, in spite of the presence of a large excess of subgenomic viral and host RNA in infecte

148 limited conditions, such as when there is a large excess of substrate over enzyme.

149 ates can often require directing groups or a large excess of substrate to achieve efficient and selec

150 d at relatively high concentrations (mM), in large excess of substrate with respect to metal complex.

151 olefination of heteroarenes without using a large excess of substrate.

152 e complex can be dismantled by addition of a large excess of tetra-N-butylammonium cations.

153 plex with widths for the individual peaks in large excess of that caused by shot noise.

154 atalysts are known, but they have required a large excess of the alkene.

155 In antisense transfected cells, a large excess of the antisense transcript was produced an

156 A reasonably large excess of the cadmium precursor, which is less rea

157 When exposed to a large excess of the cationic polymer polyethylenimine (P

158 slow, requiring multiple minutes even when a large excess of the challenging protein is present.

159 With a large excess of the deuterated olefin the first exchange

160 ntly monoaryl siloxanes, without requiring a large excess of the electrophile.

161 lasmid DNA were labeled in the presence of a large excess of the helper duplex to compete with the fo

162 To speed up the derivatization reaction, a large excess of the labeling reagent is typically used;

163 alently bound to IgE after incubation with a large excess of the ligand.

164 However, a large excess of the monomeric protein was needed for max

165 w that the formation of the 1T phase under a large excess of the NaBH4 reductant during synthesis can

166 s Ar(2)CH-PAr(3)(+)X(-) in the presence of a large excess of the nucleophiles.

167 Three relaxation processes are observed at a large excess of the nucleotide, while only two relaxatio

168 next correct dNTP, even in the presence of a large excess of the other dNTPs and rNTPs.

169 pecies (the enzyme or the substrate) is in a large excess of the other species.

170 oor regioselectivities and the need to use a large excess of the radical-accepting arene have hindere

171 hen the Fe(III)(ppq) complex is exposed to a large excess of the sacrificial electron-acceptor ceric

172 A large excess of the selenium precursor, with 5-10 times

173 Addition of a large excess of the soluble mAb subsequent to stimulatio

174 AR) expressed in Sf9 insect cells requires a large excess of the stimulatory G-protein of adenylyl cy

175 for less-reactive alkenes and alkynes, why a large excess of TMSCF(3) (1) is required in all cases, a

176 (58) modification, even in the presence of a large excess of total tRNA.

177 the dication generated in the presence of a large excess of trifluoroacetic acid had a weakened Sore

178 T which could be reversed by dilution into a large excess of tRNA substrate.

179 tial sorption of Pu(IV) in the presence of a large excess of U(VI).

180 Mixing the cells of a single clone with a large excess of uncloned cells from a subline that was r

181 ility to locate 8-oxoguanine lesions among a large excess of undamaged DNA.

182 in these extracts, even in the presence of a large excess of undamaged DNA.

183 onor ssDNA was monitored after addition of a large excess of unlabeled acceptor ssDNA by using either

184 d DNA fragments were dissociated by adding a large excess of unlabelled calf thymus DNA.

185 Finding and repairing oxoG in the midst of a large excess of unmodified DNA requires a combination of

186 chromatography using N-His-tagged FliH and a large excess of untagged FliH confirmed that FliH forms

187 5-HT(2C) receptors were co-expressed with a large excess of untagged, non-fluorescent 5-HT(2C) recep

188 x in a 1:1 complex even in the presence of a large excess of VCA.

189 , gypsum crystals are left to equilibrate in large excess of water, which promotes the growth of long

190 ing a few mutated cells in the presence of a large excess of wild-type cells requires a sensitive and

191 ffinity of trastuzumab was not affected by a large excess of Z(HER2:342)-SR-HP1 The median survival o

192 (E)-alkenyl iodides were treated with a very large excess of Zn nanoparticles, in the presence of Pd(

193 of additions to unactivated alkenes require large excesses of alkene.

194 paration difficulties and without the use of large excesses of alkylating reagent.

195 selective extraction of PF(6)(-) anions over large excesses of competing anions (Cl(-), NO(3)(-), SO(

196 Large excesses of hydrogen peroxide generated oxyferrous

197 he dilithium salts but without the requisite large excesses of inorganic salts (LiCl) or mandated dil

198 (2+) in the ER and is no longer perturbed by large excesses of native calmodulin.

199 Contrasting with the usual practice of using large excesses of one component to compete with the unde

200 es particularly easy even in the presence of large excesses of other cations, e.g. magnesium.

201 ic and natural organic compounds obscured by large excesses of other components.

202 Current desulfurization methods require very large excesses of phosphine reagents and thiol additives

203 aqueously altered CV3 chondrite Mokoia have large excesses of radiogenic chromium-53.

204 njugate in good yield with no need of adding large excesses of soluble reagent.

205 methods operate at room temperature without large excesses of the alkene substrate while, in contras

206 tion which normally arise from having to use large excesses of the conjugate.

207 With large excesses of these reagents nearly all thiols of Ke

208 h G1/S cyclins in vivo, and it is present in large excess over G1/S cyclins during the precommitment

209 Flux capacities are in large excess over physiological flux rates in low-flux m

210 ncentrations of RNA polymerase (1-123 nM) in large excess over promoter DNA.

211 condition, namely, that the substrate is in large excess over the enzyme-substrate complex.

212 ity to create a concentration of NaHCO(3) in large excess over the OXA-24 that is present in the crys

213 orated or unbound probes that are present in large excess over the target.

214 Because solar energy is available in large excess relative to current rates of energy consump

215 While 2:1 binding is observed for large excess TDG concentrations, our findings indicate t

216 rceration in Latin America has resulted in a large excess tuberculosis burden that has been under-rec

217 ding to the formation of crystal nuclei with large excesses (up to 95%) in the component of higher co