ライフサイエンスコーパス: large number

1 is the lack of susceptible small animals in large numbers.

2 ing lymph node (dLN) where they replicate to large numbers.

3 rticles where only a few of them can grow to large numbers.

4 stem, where they terminate on a particularly large number (about 460) of primary olfactory glomeruli,

5 rom almost the entire blood volume, but such large numbers and concentrations of cells are incompatib

6 ppressive properties that can be expanded in large numbers ex vivo and have been shown to prevent all

7 ssion profiles, especially when collected in large numbers, inherently contain variations introduced

8 iption start site and promoter regions and a large number of active enhancers across the genome.

9 tly, copper (oxide) nanoparticles provided a large number of adsorption sites.

10 A large number of aggressive cancer cell lines display ele

11 retic intracellular staining, we collected a large number of AL neurons in the moth, Helicoverpa armi

12 However, despite the large number of alternatives, we are still lacking a sea

13 A large number of American patients with autoimmune polyen

14 onal and protein profile analyses revealed a large number of amino acid (aa) substitutions (n = 744),

15 teins for continuous optical monitoring in a large number of applications.

16 tified in the present work) are present in a large number of bacterial and archaeal proteins.

17 decreased even as genomics has uncovered the large number of biosynthetic gene clusters (BGCs) that e

18 was observed to be due to the increase in a large number of brown pigments.

19 educer and facultative anaerobe, expresses a large number of c-type cytochromes, many of which functi

20 key GTPase in cancer, particularly because a large number of cancer cell lines with characteristic me

21 ing near-native docking conformations from a large number of candidate conformations, the so-called s

22 Further studies with a large number of cases are needed to confirm this finding

23 ite the availability of an annual vaccine, a large number of cases occur every year globally.

24 ddition to their remarkable performance in a large number of catalytic and electrocatalytic reactions

25 The stroma contained a large number of CD11c, CD68, and CD3 positive cells.

26 cytes during in vivo maturation by isolating large number of cells at key stages.

27 reatment and may require the processing of a large number of cells to assess reservoir size.

28 potential for identifying and classifying a large number of cells.

29 A large number of chemically diverse compounds that are ab

30 how that EPO-releasing cancer trap attracted large number of circulating PCa and significantly reduce

31 A large number of circulating phylogenetically distinct HI

32 preceded by segregation of the nuclei into a large number of clusters, proportional to the myotube le

33 In the last decade, a large number of common variants underlying complex disea

34 of oxidation on MS/MS fragmentation and the large number of complex and only partially chromatograph

35 numerical results suggest that, despite the large number of complexities that influence urban activi

36 tive food monitoring; however, analysis of a large number of compounds is challenged by the availabil

37 Finally, despite the large number of compounds observed in our study, we are

38 However, the large number of compounds present in the spectra hinders

39 Till now, a large number of compounds that are capable of interactin

40 is highly portable and customizable across a large number of computational environments with built-in

41 We identify a large number of condition-specific, expression quantitat

42 mputation of chemical shifts tractable for a large number of conformationally flexible metabolites.

43 hly crystalline nature of BC, as well as the large number of contact or physical crosslinking points

44 sed primarily of repetitive sequences with a large number of Copia and Gypsy elements.

45 hors have painstakingly collated data from a large number of COVID-19 patients from multiple centers

46 A large number of Cys peptides (412) were redox switched,

47 In sum, this work leverages the increasingly large number of DAP motif and ChIP-seq data publicly ava

48 MSE and their relationship with respect to a large number of data frames, bias and variance of locali

49 ) that might experience a disproportionately large number of deaths (for example 48.7%), but there is

50 ir stochastic nature imposes generation of a large number of decoys to explore adequately the solutio

51 d be less powerful due to issues such as the large number of degree of freedoms.

52 iagnostic tests were actively addressed by a large number of diagnostic test manufacturers.

53 We show how the node kernel can generate a large number of discriminative features that can be effi

54 nd maintaining accurate variant databases, a large number of disease-associated variants are still hi

55 s of the outmost importance for monitoring a large number of diseases.

56 itions could help C1- or I1-FFL to control a large number of distinct biological functions in human c

57 lities is also a complex task because of the large number of distinct disorders, which requires invol

58 1.7 Mb segment of the genome and visualize a large number of distinctive 3D chromatin folding structu

59 genes with high degree of overdispersion or large number of dropouts.

60 Major obstacle to this goal is the large number of elemental quantum gates to build even sm

61 tractable to solve as the system scales to a large number of elements.

62 ns contribute to HLB formation, and that the large number of endogenous RD histone gene copies seques

63 In a genetic screen, we discovered a large number of endolysosomal trafficking genes required

64 This analysis predicted that Sox2 targeted a large number of ethanol-dysregulated genes.

65 ats, FAN-C can be used in combination with a large number of existing analysis tools, thus greatly si

66 A large number of experimental studies show that the mutat

67 gh sampling variability(3,6,7) necessitate a large number of experiments.

68 To achieve high accuracy, we performed a large number of expert-based annotations, 72,722 in tota

69 However, the large number of factors that influence photosynthetic ra

70 are often not up to the expectation due to a large number of false positives.

71 mplies that with use of chest CT there are a large number of false-positive results.

72 important features (or predictors), among a large number of features in a given classification datas

73 e roles in immune responses by recognizing a large number of foreign antigens and thus, their genetic

74 rica using tree species lists gathered for a large number of forest and savanna sites distributed acr

75 he last Haloarchaea common ancestor gained a large number of genes and expanded its aerobic respirati

76 to familial cases of deafness, variants in a large number of genes are responsible for moderate to se

77 tistically overrepresented within a set of a large number of genes are typically used to describe the

78 ed genes in switched parasites, as well as a large number of genes encoding proteins that are either

79 A large number of genes have been implicated in neurodevel

80 on factor that regulates the expression of a large number of genes involved in cellular growth, proli

81 Mycobacterium tuberculosis possesses a large number of genes of unknown or predicted function,

82 repressor genes such as Cbfa2t3 and Jdp2 The large number of genes repressed by gain of E protein fun

83 of transcription factors is hampered by the large number of genes whose expression changes when the

84 n intermediate stage that had already lost a large number of genes, including nearly all of those inv

85 incited changes in poly(A) site choice in a large number of genes.

86 traits was Fisher's infinitesimal model of a large number of genetic variants, each with very small e

87 With a large number of genomes from non-model species becoming

88 ppears general and should be applicable to a large number of genotype-phenotype maps.

89 on of such results is challenging due to the large number of GO terms, their hierarchical and connect

90 often remain undiagnosed and untreated in a large number of high-risk patients.

91 This means that a large number of host genes that have been implicated in

92 However, a large number of human and macaque striatal voxels were n

93 A large number of human immunodeficiency virus 1 (HIV-1) i

94 prehensive information about APA events in a large number of human normal tissues.

95 To correct for a large number of hypothesis tests, most researchers rely

96 specific and is unlikely to be adaptive in a large number of important applications.

97 notherapies, accompanied by a commensurately large number of in vitro assays and in vivo models to me

98 ly small number of sites on the virus bind a large number of independently generated antibodies, sugg

99 you to profile the whole transcriptome of a large number of individual cells.

100 e with trapping arrays to efficiently trap a large number of individual microbeads with enriched exos

101 have been developed for the generation of a large number of individual reaction partitions, a key re

102 a global public health problem, affecting a large number of individuals from low-income and middle-i

103 Our collective findings point to a large number of infection-specific cis- and trans-acting

104 peat-containing receptors (NLRs) encompass a large number of innate immune sensors and receptors, whi

105 h claims and suits were infrequent given the large number of insured ophthalmologists and the large n

106 Because of the large number of isoforms, structural assignment of sacch

107 g addends to the fullerene cage results in a large number of isomers, which are generally employed as

108 enerally applicable method that exploits the large number of kinase inhibitors that have been profile

109 o explain the lack of detected homologs of a large number of lineage-specific genes in fungi and inse

110 ological differences between two groups at a large number of locations in the genome.

111 only ~3 mug of genomic DNA and can target a large number of loci in a single reaction.

112 st common polydienes (PD), are involved in a large number of materials and used in a wide variety of

113 lating outcomes to material properties for a large number of materials, and thus boosting safe-by-des

114 It contains a large number of microorganisms including fungi, which ar

115 mpacts of irradiation was underscored by the large number of miRNAs and metabolites that became signi

116 Low-coverage GBS produces data with a large number of missing or incorrect naive genotype call

117 While mutations in a large number of molecules associated with lipid metaboli

118 m disease resistance genes, including from a large number of monocots.

119 must be taken to account for the potentially large number of multi-mapping locations per read.

120 Our biosynthetic strategy exploits the large number of naturally available methyltransferases t

121 nal glycan ligands is challenging due to the large number of naturally occurring glycan structures, t

122 rough decoding analyses on recordings from a large number of neurons over a large number of trials.

123 Upon tissue injury or microbial invasion, a large number of neutrophils converge from blood to the s

124 A large number of newly synthesized membrane proteins in t

125 tribution k(-lambda), where lambda = 3 for a large number of nodes N.

126 These results suggest that a large number of non-coding loci affect the development a

127 erful genome-wide scans that have revealed a large number of novel risk loci associated with the dise

128 WGS of Moroccan individuals can identify a large number of novel SNVs and aid in functional charact

129 ts that, in longer mammalian myotubes with a large number of nuclei, the spreading stage would be pre

130 A large number of organic reactions feature post-transitio

131 lify the fabrication procedure and produce a large number of organoids (169 organoids per 3.5 cm x 3.

132 till allowed a linear classifier to decode a large number of other variables (high shattering dimensi

133 of metallic lithium or sodium held within a large number of parallel hollow tubules made of a mixed

134 come difficult to interpret when they have a large number of parameters.

135 data and high-dimensional phenotyping for a large number of participants provide an exciting opportu

136 For a large number of participating actors, we find that the c

137 pological levels, proteins that controlled a large number of pathways also controlled a network of in

138 cluding those in the C-terminal domain and a large number of patient-associated missense mutations in

139 ation of whole genome sequencing data in the large number of patients affected by congenital heart de

140 otein 4 (CTLA-4) for cancer immunotherapy, a large number of patients and cancer types remain unrespo

141 ure of the study, we suggest that a possibly large number of patients labeled as IBS-D or IBS-M may a

142 Despite the large number of patients suffering from food allergies,

143 issue but training them requires data from a large number of patients treated with each drug, limitin

144 with estimating neurological prognoses in a large number of patients who were initially comatose, in

145 ty after acute myocardial infarction (MI), a large number of patients with MI develop chronic heart f

146 l trial would be challenging in design and a large number of patients would need to be included.

147 A large number of pectin degrading enzymes have been chara

148 Given the large number of PEGylated therapeutics that are either F

149 s a resurgent infectious disease affecting a large number of people in the developing countries.

150 discovery and clinical data generated by the large number of people rapidly infected by SARS-CoV-2, c

151 Moreover, a large number of people with prediabetes are at risk for

152 s who directly infected a disproportionately large number of people.

153 nsecutive disulfide bond formation between a large number of peptide fragments.

154 hily, amine functionalities are present in a large number of pharmaceuticals, agrochemicals and biomo

155 teins requires the detection of a relatively large number of photons, hence slowing down total acquis

156 Considering the large number of physical and chemical factors involved i

157 Hydrogen sulfide has been implicated in a large number of physiological processes including cell s

158 rn Hemisphere, expanding ice sheets forced a large number of plants, including trees, to retreat from

159 PP-InsPs) is a daunting challenge due to the large number of possible isomers, the absence of a chrom

160 either cobalt or iron is added, again from a large number of possible quantities.

161 The large number of potential risk genes and the genetic ove

162 wever, made challenging by the presence of a large number of potential surface structures that compli

163 avirus disease 2019 (COVID-19) has spawned a large number of potential vaccines and immunotherapies,

164 In addition, a large number of preclinical studies have demonstrated th

165 hey are a powerful tool to analyze data with large number of predictors and limited sample size, espe

166 otype had a constitutive overexpression of a large number of protein-coding genes compared to the sus

167 ch has demonstrated that c-di-AMP binds to a large number of proteins and riboswitches, which are oft

168 logy enable us to measure the abundance of a large number of proteins at the single-cell level across

169 Poxviruses encode an exceptionally large number of proteins comprising the entry/fusion com

170 present in all kingdoms of life as part of a large number of proteins involved in several cellular pr

171 studies in cultured cells have identified a large number of proteins that can mediate PI signaling.

172 with amino acid metabolism, destabalizing a large number of proteins, and the formation of protein a

173 Here, we analyzed a large number of publically available maize (Zea mays) tr

174 However, due to the large number of radiographs obtained each day, there can

175 The reason for this large number of receptors remains unclear.

176 young decision-makers, how it changes over a large number of repetitions, and whether such changes di

177 olutionarily highly conserved and comprise a large number of residues affected by somatic cancer muta

178 cs can help address this issue by allowing a large number of samples and parallelization of experimen

179 other complex genomic variants quickly in a large number of samples for the first time, highlighting

180 esenting alternative splicing profiles for a large number of samples typically generated by single-ce

181 paper-based microfluidics has accumulated a large number of scientific publications in the fields of

182 he lack of representation by genotyping in a large number of self-reported Native Hawaiians (N = 3693

183 ate monitoring of the complex system needs a large number of sensors.

184 A large number of serologic tests, platforms, and methodol

185 nt in the study of kinetics, to the use of a large number of short trajectories.

186 A large number of social science field experiments do not

187 A large number of socioeconomic, phenotypic and psychologi

188 Minimizers are used in a large number of softwares and pipelines to improve compu

189 tion models don't allow for coexistence of a large number of species, it was recently shown that meta

190 he developed nanoMIP offers the advantage of large number of specific recognition sites with tailored

191 echanisms and pharmacology, and, despite the large number of structures included, reveals the need fo

192 A large number of studies are being conducted to evaluate

193 A large number of studies conducted during the past 20 yea

194 A large number of studies have shown that the status of CT

195 The large number of studies in this area has, however, an im

196 Despite the large number of studies performed, specific markers are

197 We have reviewed the results of a large number of studies that assessed the effects of dif

198 whether this finding can be replicated in a large number of subjects.

199 Env is covered with a large number of sugar-based glycan forms; about 50% of t

200 e number of insured ophthalmologists and the large number of surgical cases requiring various types o

201 A large number of synaptic vesicles are released during hi

202 Here, we showed that when a large number of synaptic vesicles are released during hi

203 A large number of synaptic vesicles are released during hi

204 ator 1 (WWTR1; also known as TAZ) regulate a large number of target genes, acting as coactivators of

205 cept that has been successfully applied to a large number of target structures, but requires excess q

206 ncrease in demand for antibody testing and a large number of tests are already marketed or are in the

207 the prevailing tectonic stress (prograde), a large number of them are displaced in the opposite (retr

208 A large number of them, 675 genes, were common to both set

209 However, technical barriers to tracking a large number of these rare lineages in bacterial populat

210 gnosis requires labor-intensive reading of a large number of tissue slides with high diagnostic accur

211 iral mRNAs and non-coding transcripts, and a large number of transcript isoforms, including transcrip

212 During differentiation a large number of transcripts, including many encoding key

213 as a single step gradualistic process with a large number of transition cells between the basal and s

214 provide a highly selective environment for a large number of transmembrane and membrane-associated pr

215 rdings from a large number of neurons over a large number of trials.

216 lt in suboptimal module identification and a large number of unassigned features.

217 c tests for fish allergy are hampered by the large number of under-investigated fish species.

218 A large number of unique MYBPC3 variants and relatively sm

219 The comparative testing of a large number of vaccine candidates requires a quantitati

220 stering is due to the cumulative effect of a large number of variants of individually small effect.

221 Here, we examine a large number of variants within and between species for

222 ynthesis of precursor libraries comprising a large number of variants.

223 red by their ribbon synapses, which tether a large number of vesicles at the IHC's presynaptic active

224 After the LEEFT, a large number of viable cells with impaired cell membrane

225 c metabolism genes (adhE, pflA, nrdDG) and a large number of virulence factors (lukSF, lukAB, nuc, ge

226 AggR activates transcription of a large number of virulence genes, including Aar, which in

227 Despite the large number of web-based genome browsers available nowa

228 oping forelimbs, both TBX3 and BCL9 occupy a large number of Wnt-responsive regulatory elements, geno

229 However, high variability and a large number of zero counts present challenges for analy

230 We found large numbers of "infrequent hitters" using this model l

231 cient, hu cytokine-secreting, mice that have large numbers of activated hu mast cells.

232 Large numbers of AM fungal spores were present in the ai

233 Transcripts that share large numbers of ambiguously-mapping fragments with othe

234 A critical next step is to integrate large numbers of artificial atoms with photonic architec

235 Gplas facilitates the analysis of large numbers of bacterial isolates and allows a detaile

236 EMENT Most social-living vertebrates produce large numbers of calls per day, and the calls have promi

237 ting reliable single-cell DNA methylomes for large numbers of cells and samples.

238 The analysis of large numbers of cells from a population results in info

239 ase epidermolysis bullosa (EB), we show that large numbers of cells, often in excess of 100 million p

240 terns or shapes can only be constructed from large numbers of cells, with cells in different parts of

241 Screening large numbers of clones expressing different trispecific

242 of infected individuals are responsible for large numbers of COVID-19 transmission.

243 ing are complex and compositional because of large numbers of detectable taxa, and because microbiota

244 of transformations, chemists have developed large numbers of dinuclear transition-metal complexes wi

245 tions: first, that driven systems containing large numbers of dislocations are subject to the second

246 tectures derives from fragmented sampling of large numbers of disparate molecules.

247 rates and low E(a) values are attributed to large numbers of edge, defect, and other low coordinatio

248 rming efficient reagent exchange on chip for large numbers of embryos remains a bottleneck.

249 odeling and degradation can occur, releasing large numbers of endogenous peptides.

250 city of the immune system to affinity-mature large numbers of Env-specific B cell lineages simultaneo

251 CRC patients whose tumors are infiltrated by large numbers of eosinophils also exhibit robust CD8 T c

252 The aggregation and joint analysis of large numbers of exome sequences has recently made it po

253 The large numbers of expanded HSCs enable HSC transplantatio

254 In the method described here, we generate large numbers of free-floating GUVs through the rehydrat

255 Approaches that combine large numbers of genes outperformed single gene methods

256 ng this strategy, we were able to filter out large numbers of genes that are unlikely to be direct ta

257 oan transcription factors typically regulate large numbers of genes.

258 erwise not routinely feasible because of the large numbers of HSCs required.

259 var.f90, for estimating gametic variance for large numbers of individuals.

260 f prior immunity to COVID-19 has resulted in large numbers of infected patients across the globe and

261 ient mutagenesis makes it possible to detect large numbers of insertions in essential genes immediate

262 Our approach may be scaled to large numbers of ions with arbitrarily small separation

263 Since large numbers of isotopes can be employed as labels, mas

264 C functions as a Golgi casein kinase and has large numbers of kinase substrates within the secretory

265 data and extending capabilities to quantify large numbers of known and unidentified metabolites dete

266 , both aneuploid and euploid cells contained large numbers of likely clonal insertions.

267 MYC controls the transcription of large numbers of long noncoding RNAs (lncRNAs).

268 hed against a database of GESs obtained from large numbers of measurements, such as different genetic

269 Current methods often report large numbers of motifs, making it difficult to perform

270 The ability to assemble large numbers of nearly indistinguishable and tunable ar

271 neurophysin-immunoreactivity was detected in large numbers of neurosecretory dense-cored vesicles, ma

272 Large numbers of neutrophils are recruited into the airw

273 ondition characterized by the recruitment of large numbers of neutrophils into the lungs.

274 in the replisome to support the synthesis of large numbers of Okazaki fragments.

275 intervention that can be rapidly deployed to large numbers of participants, and resulted in meaningfu

276 ct for batch effects and integrate data from large numbers of patients and conditions across batches,

277 We demonstrated feasibility of screening large numbers of patients at numerous accruing sites in

278 Currently, multiple medicines prescribed to large numbers of patients influence the Treg compartment

279 cular technologies with potential to benefit large numbers of patients.

280 on, agriculture, and construction, can bring large numbers of people into new settlement areas and ca

281 ations are needed for indoor activities with large numbers of persons (places of worship and public t

282 However, collecting phenotypic data for large numbers of plants remain a bottleneck.

283 ic regions for many individuals sampled from large numbers of populations.

284 and disease pathogenesis, especially because large numbers of progeny can be obtained, overcoming the

285 tion techniques(21) may allow for scaling to large numbers of qubits in the future.

286 In large numbers of responding cells, mixtures of odors did

287 fers sensitive and precise quantification of large numbers of samples and has thus found applications

288 arch, more and more studies are conducted on large numbers of samples.

289 nd is particularly advantageous for sampling large numbers of sites.

290 seful isoflavone composition predictions for large numbers of soybean samples can be obtained from qu

291 Large numbers of stress-inducible poly(A) sites could no

292 The presence of large numbers of symbionts near the epithelial surface o

293 Thus, when large numbers of synaptic vesicles are released during h

294 effective control of these insects requires large numbers of trained extension agents who try to spo

295 In particular, VACV genes produce large numbers of transcript isoforms that vary in their

296 08 [95% CI 2.52-3.77]), and sponsors running large numbers of trials were significantly more likely t

297 nsive set of plant traits and growth data on large numbers of tropical trees, considerable uncertaint

298 ich remains costly for purposes of screening large numbers of unknown samples during routine surveill

299 or V. cholerae lineage occasionally grows to large numbers on particles but remain undetectable using

300 We associate small numbers with the left and large numbers with the right side of space.