ライフサイエンスコーパス: large scale

1 sets allowing this technology to be used at large scale.

2 ay make it possible to monitor well-being at large scale.

3 pplied to synthesize desirable products on a large scale.

4 mpact on the evolution of Earth systems on a large scale.

5 e in generating nonimmunogenic antibodies in large scale.

6 features and global pattern attributes on a large scale.

7 and moisture storage was greatest (+36%) at large scales.

8 sphere-like liquids have on intermediate and large scales a simple structural order given by alternat

9 re model in which collective cell migration, large-scale actin-network fusion, and purse-string contr

10 ime below 5 min, our method is applicable to large scale aDNA genomic studies.

11 S-turbo, purpose-built software designed for large-scale analyses of splicing, and identified 13,149

12 odological differences present challenges to large-scale analysis across datasets.

13 rted ground shaking distribution through the large-scale analysis of real-time search queries from a

14 n Fund program with the goal of generating a large-scale and comprehensive catalogue of perturbation-

15 ut reflects the precise coordination of both large-scale and local cortical networks.

16 Large-scale and long-term changes in fish abundance and

17 peptide tag can easily be accomplished on a large-scale and whether integrated reporter faithfully r

18 One of the challenges associated with the large scale application of this technique to zebrafish i

19 tegies ultimately will lead us closer to the large-scale application of LMBs which often is called th

20 nogenerator (TENG) is always crucial for its large-scale application on Internet of Things (IoTs) and

21 omics, but cost and labor requirements limit large-scale application.

22 The results pave the way for practical large-scale applications of high-performance SDRC for hu

23 antial step towards quantum communication at large scale, as well as novel explorations in microwave-

24 -genome sequencing data are often applied to large-scale bacterial comparative genomics projects but

25 cant sequencing and labor cost reductions in large-scale bacterial genome projects.

26 nstrate that MoSeq can meaningfully organize large-scale behavioral data, illustrate the power of a f

27 Large-scale biodiversity changes are measured mainly thr

28 y, we find that larval tolerance can explain large-scale biogeographic patterns for this species acro

29 halamic nuclei are among the most consistent large-scale brain imaging findings in schizophrenia.

30 Large-scale brain imaging studies by the ENIGMA Consorti

31 Drug-resistant focal epilepsy is a large-scale brain networks disorder characterized by alt

32 e the implementation of cognitive control by large-scale brain systems.

33 throughput variant calling applications on a large scale but lack the manpower and/or computational e

34 omic distance effect or risk being misled by large-scale but artifactual differences.

35 to successfully combat agricultural pests at large scale, but not mosquitoes, mainly because of chall

36 netic constraints and spatial variability at large scales by combining openly available species' trai

37 Large-scale cancer genomic studies enable the systematic

38 rm-integrated algorithms could be applied to large-scale cancer studies, such as The Cancer Genome At

39 local communities (IPLCs) as buffers against large-scale carbon emissions across a nine-nation networ

40 The data also provide a large-scale case study for sequence-based machine learni

41 where genetic analyses are strongest, versus large-scale, case-control studies.

42 (3)-Bn-GalNAc(Ac)(3) as a novel precursor in large-scale cell cultures to generate usable amounts of

43 tterns despite noisy morphogen signaling and large-scale cellular rearrangements during morphogenesis

44 resentations and cognitive operations within large-scale cerebral networks generate subjective memory

45 properties of the cornea, the absence of any large-scale changes following treatment confirms the pot

46 has been widely implicated as the source of large-scale changes in the subpolar marine environment.

47 n important role in chromatin compaction and large-scale chromatin organization.

48 However, this notion has been challenged by large-scale clinical trials demonstrating that, in the m

49 hat cause scarring and may be impractical in large-scale clinical trials.

50 small number of results from well designed, large-scale, clinical studies there is considerable vari

51 Recent large-scale collaborations are generating major surveys

52 ric genetics have been made possible through large-scale collaborative efforts.

53 the viscosity to zero, [Formula: see text], large-scale collective motion emerges in the quiescent s

54 ble designs of TADF molecules, pure organic, large-scale, color tunable, and low-cost room-temperatur

55 aling can be an effective way of determining large-scale community connectivity.

56 We report the first large-scale, community-based, health survey of HTLV-1 an

57 Using large-scale comparative genomics and advanced orthology

58 DeepRiPP pinpoints target metabolites using large-scale comparative metabolomics analysis across a d

59 tation detection approach that is useful for large-scale comparative protein function studies.

60 This study provides the first large-scale comparison of commercial molecular assays fo

61 loops, topologically associated domains, and large-scale compartments.

62 n of single-cell data that enables efficient large-scale computations.

63 correlations between fluorophore motions and large-scale conformational changes between LIV-BPSS doma

64 of anxiolytic action, with only OXT inducing large-scale connectivity changes of potential therapeuti

65 In large-scale consortia focusing on GxE interactions in wh

66 use residual uncorrected stratification from large-scale consortium studies was considered responsibl

67 role in the development of prosociality and large-scale cooperation by allowing cooperators to clust

68 iconformist bias to explain the evolution of large-scale cooperation, and subsequent research has ext

69 se to systematic frequency differences among large-scale cortical networks and predict individual-spe

70 ng cortical areas, as a general principle of large-scale cortical organization.

71 of comprehensive tools for use on data from large-scale CRISPR-based genetic screens.

72 Understanding large-scale crop growth and its responses to climate cha

73 A pressing question is to understand how large-scale cross-linking mass spectrometry (XL-MS) can

74 strate a new avenue that is ready to use for large-scale cryo-EM-based structure modeling and atomic-

75 substantial quantities of the enzyme causing large-scale CSPG digestion, facilitating the migration a

76 ks and how new technologies allow for rapid, large-scale data generation at the point of care.

77 FUpred was tested on a large-scale dataset consisting of 2549 proteins and gene

78 Here, we present a large-scale dataset of 849 3D reconstructions of the bas

79 Utilizing a large-scale dataset which includes 3.5 billion entry and

80 ing variance components do not scale well to large-scale datasets of genetic variation.

81 Technological advances now enable large-scale datasets, including DNA and RNA sequence dat

82 by visual analysis but could be learned from large-scale datasets.

83 iations within the comet's body testify that large-scale deformation occurred in a brittle-plastic re

84 cterizations from atomic-scale structures to large-scale device performances in 2D semiconductors, th

85 Through large-scale deworming programs, World Health Organizatio

86 rmation about visible edges and by analyzing large-scale differences between figure and background.

87 the present study include the following: (i) large scale differential binding sites (DBS) were availa

88 that enables massive hiPSC-CM expansion for large-scale drug screening and tissue engineering applic

89 relationship between ribosome structure and large-scale dynamics, and it suggests how next-generatio

90 nimal demography, etc.) will aid much-needed large-scale ecological data integration.

91 However, high performance, large-scale EGT arrays, and EGT application for spatiote

92 rials, little has been done in examining the large-scale electronic integration of these devices to i

93 nsor, but also presents a paradigm shift for large-scale energy harvesting by TENGs.

94 Large-scale energy storage is becoming increasingly crit

95 teries (RFBs) are promising alternatives for large-scale energy storage.

96 We therefore used a large-scale enhanced yeast one-hybrid assay to identify

97 Large-scale environmental forces can influence biodivers

98 Although T cell commitment is accompanied by large scale epigenetic changes, we observed that the maj

99 We provide large-scale evidence that air pollution, specifically oz

100 Our study presents the first large-scale, exome-wide analysis of rare variants in AMD

101 sis of nearly 10,000 wild-type mice from two large-scale experiments revealed that the largest variat

102 llaboration for Reproducible and Distributed Large-Scale Experiments that crowdsources data from fami

103 we examine food webs in three long-term and large-scale experiments to test how resource availabilit

104 anTraX can handle large-scale experiments with minimal human involvement,

105 ed the practicality and economic benefits of large-scale extraction for industrial applications.

106 It is intuitively expected that the large-scale extraction of the material will improve the

107 vely make the network more resilient against large-scale failures.

108 Large-scale family studies on the co-aggregation of thes

109 potential for natural product synthesis and large-scale fermentation in yeast.

110 Results from a large-scale field study conducted in Nairobi, Kenya, are

111 Moving from small to large scales, first, tree-level models that simulate the

112 ving data analysis pipelines associated with large-scale fitness screens, including image acquisition

113 ding imprints of the crystal symmetry on the large-scale flow pattern.

114 erve the configurational information, I, and large-scale fluctuations, Q, of the microscopic model.

115 cytoskeletal structures are able to generate large scale forces that can extensively remodel epitheli

116 In this context, large-scale forcing of ISM rainfall variability with mul

117 The one outstanding candidate for large-scale functional HGT is the holoparasite Lophophyt

118 We performed large-scale gene expression and genotype analyses in pos

119 ear pore complex (NPC), and it also promotes large-scale gene-NPC interactions.

120 an online repository that provides access to large-scale genetic and phenotypic datasets with more th

121 The increasing availability of large-scale genome-wide association study (GWAS) for ast

122 phenotypic heterogeneity and the absence of large-scale genomic screens.

123 More recently, large-scale genomic studies have expanded the clock into

124 The advances of large-scale genomics studies have enabled compilation of

125 c factors influencing haemodynamic traits in large-scale genotyped and phenotyped cohorts where local

126 ey, and maize, and concluded an approach for large-scale germination scoring.

127 This large-scale GWAS in a Japanese population provides insig

128 and deformation while being manufactured at large scales have remained a rare find.

129 fluence risk of cardiometabolic disease, but large-scale high-resolution studies are lacking.

130 re the perfect test bed to better understand large-scale human behavior in interacting contexts.

131 sitivity of tropical soil carbon turnover to large-scale hydroclimate variability remains poorly unde

132 the influence on the 3D reconstruction from large-scale image distortion and deformation.

133 pic PDAC transplant mouse model to perform a large-scale, in vivo screen of 16 single-agent and 41 tw

134 This model is embedded within a large scale individual-based model of malaria transmissi

135 Using large-scale individual-based simulations, we aim to iden

136 In the present large-scale, individual patient data pooled analysis of

137 These advantages could be exploited for large-scale industrial applications and nanodevices.

138 tely-sensed environmental parameters provide large-scale information on the potential availability of

139 9 (COVID-19) pandemic, Singapore implemented large-scale institutional isolation units called Communi

140 al travel restrictions and by the province's large-scale intensive surveillance and intervention meas

141 rk analysis combining functional genetic and large-scale interaction data can predict function of nov

142 g with 14 new reference assemblies, revealed large-scale intermixing of diverse genotypes, as well as

143 Here we integrate data from UK Biobank and a large-scale international collaborative effort, includin

144 TaNT clearly provides a safe strategy for large-scale ivermectin treatment and overcomes a major o

145 l framework involving the decomposition of a large-scale LIP into sub-problems of low complexity and

146 ale paves a crucial foundation for realizing large-scale LN photonic integrated circuits that are of

147 Future large-scale longitudinal studies are required to determi

148 quid bone biopsy for FGF23 dynamics' enables large-scale longitudinal studies of FGF23 regulation tha

149 ative function and family annotations; (2) a large-scale M. truncatula RNA-sequencing-based gene expr

150 In this study, we performed a large-scale macroevolutionary study to understand how bo

151 xisting approaches for estimating V(cmax) at large scale mainly rely on empirical relationships with

152 A modulated bi-phase synthesis towards large-scale manganese 1,4-benzenedicarboxylate (MnBDC) M

153 Climate engineering-the deliberate large-scale manipulation of the Earth's climate system-i

154 le tool for fast prototyping and potentially large-scale manufacturing of functional devices.

155 ere, we introduce a method named EXoO-Tn for large-scale mapping of Tn-glycosylated proteins and glyc

156 nection between a core metabolic process and large-scale mechanics in a rapidly developing embryo.

157 Over the past years, many large-scale MeSH indexing approaches have been proposed,

158 We propose FullMeSH, a large-scale MeSH indexing method taking advantage of the

159 This large-scale meta-analysis indicates a clear distinctive

160 uality control samples, ncGTW applied to two large-scale metabolomics LC-MS datasets identifies many

161 the value of dissecting tumor immunity using large-scale methods.

162 The large-scale microfluidic single-bead trapping permits ma

163 Overlapping large-scale molecular dynamics simulations capture the a

164 The combination of large-scale multi-modal imaging with extensive phenotypi

165 Finally, we apply this model to large-scale multielectrode recordings to illustrate how

166 However, integrating these large-scale multiomics data and discovering functional i

167 ity as a biomarker for brain aging using two large-scale (n = 292, ages 20 to 85 y; n = 636, ages 18

168 ers of childhood that involve disruptions in large-scale network connectivity.

169 studies of the brain, from the molecular to large-scale network level, is ensuring the accuracy and

170 Such intercellular bands extended into a large-scale network of mechanically connected cells, in

171 that filler utterance would often occur when large-scale networks across the association and visual c

172 lpha oscillations with higher frequencies in large-scale networks connecting anterior and posterior b

173 The human brain is organized into large-scale networks identifiable using resting-state fu

174 ms by which DMN couples with other canonical large-scale networks, including language and control net

175 ty (FC) studies have identified at least two large-scale neural systems that constitute cognitive con

176 ) studies have reported altered integrity of large-scale neurocognitive networks (NCNs) in dementing

177 duce common organizing principles underlying large-scale nuclear architecture across human cell nucle

178 Here, we describe an approach to large-scale nuclear architecture in metazoans that incor

179 ral assays to improve early accessibility of large-scale nucleic acid testing.

180 n omics screening to populations enrolled in large-scale observational and clinical trials.

181 shift from small-scale biological control to large-scale oceanographic control of these communities.

182 predicting an exact metal contaminant from a large scale of contaminant pool with high prediction acc

183 Whereas folding of genomes at the large scale of epigenomic compartments and topologically

184 the added advantage to robustly produce the large scale of proteins with native-like fold and hence

185 ed on published literatures, PPI-network and large-scale omics data.

186 Our findings suggest that a large-scale outbreak is likely after a single introducti

187 Large scale outbreaks have not been reported following p

188 DPPA3 in turn drives large-scale passive demethylation by directly binding an

189 ntal and taxonomical structure, we show that large scale patterns in the EMP can be reproduced by con

190 s an efficient and user-friendly toolbox for large-scale personalized constraint-based metabolic mode

191 ttleneck and to explore advanced methods for large-scale phenotyping data acquisition and processing

192 experimental studies of virus evolution and large-scale phylodynamic analyses.

193 ntories from wet to arid biomes), and a new, large-scale phylogenetic hypothesis for the genera that

194 HogProf enables large-scale phylogenetic profiling across the three doma

195 Here we report an open, large-scale physiological survey of activity in the awak

196 Using a numerical simulation of a large-scale plume, the lobster is used as a framework to

197 ture, a self-consistent model for how such a large-scale polygonal jet forms in the highly turbulent

198 ndardization of immunophenotyping methods in large scale population studies that provides a rapid, ac

199 dy aimed to validate its prognostic value in large-scale population and explore the impact of menopau

200 investigate transmission chains and explore large-scale population dynamics, such as the spread of a

201 human disease, and demonstrate the power of large-scale population sequencing data in studying non-c

202 -6 in a further 740 cases with controls from large-scale population studies (odds ratio of 2.5, 95% c

203 imester of pregnancy with preterm birth in a large-scale population-based retrospective cohort study.

204 e aimed to investigate this association in a large-scale population-based study in England.

205 The platform makes possible large-scale prediction and curation protein interactions

206 ions, and their limited solubility precludes large-scale processing into more useful morphologies and

207 d region (3'-UTR) of the SCoV2 genome, their large-scale production and NMR-based secondary structure

208 to be utilized in industrial applications, a large-scale production capacity for CNCs must exist.

209 type, and demonstrate the usefulness of the large-scale production efforts of the ENCODE Consortium.

210 g these components), as well as optimize the large-scale production of AAV.

211 n order to translate bench-top research into large-scale production of hydrogen.

212 The manufacture of sensors using large-scale production techniques, such as roll-to-roll

213 unt for ~50% of the projected total cost for large-scale production.

214 This large-scale project used machine learning (i.e., Random

215 for localized prostate cancer by integrating large-scale prostate cancer genomes and the prostate-spe

216 e a new high-throughput ultrafast method for large-scale proteomics approaches by speeding up the cla

217 ally deleting all FIKK kinases combined with large-scale quantitative phosphoproteomics we identified

218 l neural network allowed high-throughput and large-scale, quantitative and comparative analyses of va

219 With recent advances in large-scale, quantitative omics methods as well as in in

220 k also constitutes an important step towards large-scale quantum dot simulators of correlated electro

221 and providing the building block of a future large-scale quantum network.

222 demonstrate robust frequency definition for large-scale rare variant association studies, identify C

223 onsumer wearable devices may be used for the large-scale, real-time detection of respiratory infectio

224 nts, to be a powerful tool for investigating large-scale rearrangements in genome structure upon cell

225 continuum model of the genome, we study the large-scale rearrangements of chromatin that happen at d

226 Millennium (LM) relationships among several large-scale reconstructed climate variables characterizi

227 , SAE and high-dose radiation exposure using large-scale registry data.

228 Multiple large-scale restoration strategies are emerging globally

229 In this large-scale retrospective data-driven analysis, we exami

230 Through an application in nine natural large-scale rock joints, nine consecutive sampling sizes

231 y [4] in Africa, Asia, and New Guinea, where large-scale rubber cultivation is viable, and simulated

232 ctrometry has the potential to provide rapid large-scale sample analysis at a speed of more than one

233 In an era of large-scale science-related challenges and rapid advance

234 important genetic drivers and that targeting large-scale SCNAs may improve pRCC treatment, which is c

235 of congenital disease phenotypes for guiding large-scale screening and medicinal chemistry have not b

236 eanup prior to analysis and are too slow for large-scale screening campaigns.

237 This new assay now enables straightforward large-scale screening for PSD inhibitors against pathoge

238 affect methanotrophic responses to potential large-scale seafloor methane releases in ways that provi

239 epping-stone to the development of the first large-scale sediment remediation technique for microplas

240 ng the date of origin of genetic variants in large-scale sequencing data sets.

241 Large-scale sequencing efforts have led to the classific

242 Large-scale sequencing studies have also uncovered genet

243 implify frontline diagnostics and facilitate large-scale serological surveillance and postvaccination

244 a panel of active site inhibitors, including large-scale shifts in the conformational equilibria of t

245 Our findings suggest that continued large-scale shifts in the relative abundance of morpholo

246 Large-scale simulation experiments without pleiotropic e

247 llustrate successful applications of BMTK to large-scale simulations of a cortical area.

248 We combine large-scale simulations of membrane-embedded PSII with h

249 We illustrate our approach with large-scale simulations of various nodal knots and an ex

250 Here, using state-of-the-art analyses of large-scale single-cell and single-nucleus transcriptome

251 Large-scale single-cell genomics, imaging technologies,

252 To process large-scale single-cell RNA-sequencing (scRNA-seq) data

253 e that the ability of humans to cooperate in large-scale societies is unique in animal life, it remai

254 Our data on large scale SSR based genetic diversity and population s

255 s can also be applied to other domains where large-scale statistical analyses over encrypted data are

256 nome folding and predicts the impact of both large-scale structural and single base-pair variations.

257 of compounds exist, the ability to carry out large-scale structure-based virtual screening on compute

258 Further large-scale studies are needed to confirm these findings

259 of the UbiFast method makes it suitable for large-scale studies in primary tissue samples.

260 eneric, low-cost sofosbuvir and daclatasvir, large-scale studies in resource-limited countries are no

261 By analysing data from large-scale studies of households, we estimate that pneu

262 iation in defence, highlighting the need for large-scale studies that can differentiate competing env

263 results and are particularly important with large-scale studies.

264 r improving the quality of results, enabling large-scale studies.

265 ficits in autism spectrum disorder (ASD), no large-scale study has been conducted.

266 A large-scale study now reveals that inhibition of recepto

267 A large-scale study shows that high fruit and vegetable co

268 cted mosquitoes, and use of these males in a large-scale suppression trial in Fresno County, Californ

269 The field is now moving from mostly large-scale supraregional studies to a more local perspe

270 Using data from two previous large-scale surveys [9, 10] separated by a decade, and i

271 d co-culture bioprocess applications rely on large-scale suspension fermentation technologies that ar

272 Here, we show the first simple large-scale synthesis of free-standing Bismuthene, to ou

273 highlight the potential of photo-PISA in the large-scale synthesis of functional, proteolytically res

274 The approach paves the way for large-scale synthetic preparation of pocket-modified van

275 is significant knowledge gap, we performed a large-scale systems-level analysis of the protein-DNA in

276 ZBTB18, TCF12, SPEN, and LEO1) based on this large-scale targeted sequencing effort.

277 lgorithm to identify emerging phenomena from large-scale temporal plant phenotyping experiments.

278 This large-scale, theoretically-driven study of intentional r

279 A large scale three-dimensional particle-in-cell (PIC) sim

280 athology is not suitable for visualizing the large-scale tissue and native 3D organ structure due to

281 ical role, because they can be deployed at a large scale to monitor the individuals' drug transcourse

282 These RNA polymerase mutations cause large-scale transcriptional changes without altering sus

283 esian framework, in order to learn and model large-scale transcriptional networks.

284 human isolates, suggesting the occurrence of large-scale transposition in genomes of bovine and human

285 e series originate from the superposition of large scale trends and small scale fluctuations.

286 -functioning ASD in adult men, although this large-scale trial suggests oxytocin's possibility to tre

287 prespecified meta-analysis of the two single large-scale trials assessing the effects of SGLT2 inhibi

288 but there have been few long-term, high-dose large-scale trials.

289 Our method adds a new dimension to large-scale tRNA functional prediction and will help pri

290 Other planetary-scale waves and large-scale turbulence act in the opposite direction.

291 metrics has been too resource intensive for large-scale use.

292 ls; staggered introductions; and a one-time, large-scale vaccination campaign.

293 vironmental productivity patterns, including large-scale variability in pathogens, vectors and associ

294 numerical models are widely used to estimate large-scale variations in ocean carbon export, but the r

295 t understanding on the mechanisms underlying large-scale variations of soil nitrification and benefit

296 Large-scale virulence and infectivity assays using insec

297 els matched in their number of parameters in large-scale visual recognition tasks on natural images.

298 ating skyrmions at designated locations on a large scale, while controlling the skyrmion patterns, is

299 Together, these studies demonstrate how large-scale, wild-type approaches can help dissect the p

300 ees, associated with the annual operation of large-scale wood pellet mills.