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1 RT has not been systematically assessed in a large-scale clinical trial.
2      These results require confirmation in a large-scale clinical trial.
3 es were assessed to better plan for a future large-scale clinical trial.
4 hat cause scarring and may be impractical in large-scale clinical trials.
5  promising agents have been disappointing in large-scale clinical trials.
6 hibitors on hard renal outcomes, as shown in large-scale clinical trials.
7  requires difficult-to-conduct and expensive large-scale clinical trials.
8  due to the lack of conclusive evidence from large-scale clinical trials.
9 e stress in CVD remain to be investigated in large-scale clinical trials.
10 hich are unknown and need to be evaluated in large-scale clinical trials.
11 ng-term safety has yet to be demonstrated in large-scale clinical trials.
12 fficacy of a microbicide before embarking on large-scale clinical trials.
13  by GlaxoSmithKline and Merck have completed large-scale clinical trials.
14  as relatively ineffective when entered into large-scale clinical trials.
15 uld investigate their therapeutic utility in large-scale clinical trials.
16 e initiating autoimmune process have entered large-scale clinical trials.
17 cer in the population should be confirmed in large-scale clinical trials.
18  to reduce the risk of gout by 30% to 50% in large-scale clinical trials.
19 nd data collection, which will propel future large-scale clinical trials.
20  subtypes are amenable to properly designed, large-scale, clinical trials.
21                    However, before launching large-scale clinical trials, a better understanding of t
22 id approaches in the design and execution of large-scale clinical trials and repurposing of existing
23 cular AMD was lower than that recommended by large-scale clinical trials, and rates of discontinuatio
24 o significantly improve glycaemic control in large-scale clinical trials, and short-term ranolazine t
25 s to reduce cardiovascular mortality, before large scale clinical trials are undertaken.
26                                              Large-scale clinical trials are currently evaluating sen
27                                              Large-scale clinical trials are essential in cardiology
28                                       Though large-scale clinical trials are essential to confirm the
29 flammatory role of albumin, but confirmatory large-scale clinical trials are lacking.
30                             Clearly targeted large-scale clinical trials are needed to evaluate the r
31 pproaches be vigorously pursued and that any large-scale clinical trial be carefully executed to avoi
32 l global assays of fibrinolysis will require large-scale clinical trials before their prognostic powe
33                          More recently, in a large-scale clinical trial, bimodal neuromodulation comb
34  will aid pharmaceutical companies to design large-scale clinical trial by assessing potentially haza
35   To date, there are no published results of large-scale clinical trials comparing conventional doses
36  However, this notion has been challenged by large-scale clinical trials demonstrating that, in the m
37                                          Few large scale clinical trials exist with biopsy or magneti
38 me these limitations and have been shown, in large-scale clinical trials for acute coronary syndromes
39 -CoV for humans or animals, and there are no large-scale clinical trials for therapies against MERS-C
40 ent in some countries, despite an absence of large-scale clinical trials for this indication.
41                                     A recent large-scale clinical trial found that an initial invasiv
42                   Thus, using samples from a large-scale clinical trial from stage II and III melanom
43 ins a relatively rare disorder, and as such, large-scale clinical trials have not been completed, ren
44                                         Only large-scale clinical trials, however, can determine the
45                   After decades of research, large-scale clinical trials in patients diagnosed with f
46 ould be a more informative test, and propose large-scale clinical trials in patients who are believed
47  Dougherty and colleagues reported the first large-scale clinical trial of photodynamic therapy (PDT)
48  company database was published, followed by large-scale clinical trials of EGFR TKIs demonstrating t
49                                   In robust, large-scale clinical trials of grass pollen sublingual t
50 ortunately, there has been little success in large-scale clinical trials of myeloid cell modulators,
51 gents in resistant patient populations, with large-scale clinical trials ongoing to more thoroughly t
52 cal trials but also highlighted the need for large-scale clinical trials structured according to a ma
53                                     Existing large-scale clinical trials such as the GISSI-Prevenzion
54 n anaesthesia has recently been evaluated in large-scale clinical trials that have demonstrated xenon
55  demonstrated to suppress atherosclerosis in large-scale clinical trials through a yet-unknown mechan
56 geted product innovation, and well-designed, large scale clinical trial to confirm efficacy, optimize
57 ics, this strategy has not been subjected to large-scale clinical trials to establish safety and clin
58                                         In a large-scale clinical trial, treatment with Herceptin (tr
59 ventions, should they be proven effective in large-scale clinical trials using appropriate controls,
60                      The failure of numerous large-scale clinical trials, which aimed to treat sepsis
61 n isolated MR and provides the impetus for a large-scale clinical trial with clinical outcomes.