コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 bits phosphorylation in the second protomer, leading to ~50% phosphorylation of the available sites i
2 5.50 +/- 0.08, the uptake process is slower, leading to 98% Tc removal (log K(d) = 4.5 +/- 0.1) after
3 l-based results suggest financial incentives leading to a 10-minute decrease in door-to-needle time s
4 s were missed in 1.2% (12/1,003) on PET/MRI, leading to a change in TNM staging in 0.5% (5/1,003).
5 t findings were detected in 5.3% (53/1,003), leading to a change in TNM staging in 2.9% (29/1,003) du
7 he creation of host nutritional deficiencies leading to a compromised host-symbiont state and (ii) th
8 involving environmental and genetic factors, leading to a decrease in hearing sensitivity, threshold
9 ndrocyte differentiation in the mPFC at P15, leading to a depletion of the oligodendrocyte progenitor
10 resses the underlying mechanisms and factors leading to a disturbed structure-function relationship.
11 micromotors (self-fluid mixing capabilities leading to a faster assay in low sample volumes) and ele
12 third in comparison with the counterfactual, leading to a global cooling of - 0.1 milli degrees C in
13 thly blood transfusions throughout her life, leading to a hepatitis C virus infection (which was trea
14 n an initial tranche of 485,856 individuals, leading to a high-quality dataset of 459,777 unique indi
15 scales relevant for the implemented models, leading to a higher frequency of nearby premises compare
16 last years due to instrumental improvements leading to a higher sensitivity and selectivity of instr
17 umulating in biota and metabolizing to PFBS, leading to a higher than expected TMFs for this compound
19 me a global pandemic in developed countries, leading to a host of medical conditions that contribute
20 ynthesis of the purine deoxyribonucleosides, leading to a mixture of deoxyadenosine, deoxyinosine, cy
21 d proteasomal degradation of KIF1A proteins, leading to a near depletion of KIF1A protein late in inf
22 l forest loss currently exceeds forest gain, leading to a net greenhouse gas emission that exacerbate
23 ng block of future mechanical metamaterials, leading to a new class of tunable metamaterial over a wi
24 ll four instruments had similar performance, leading to a possible greater practical implementation o
25 dimensional Reynolds-Averaged Navier Stokes, leading to a precise evaluation of the thermal load and
26 ed, while total protein levels are enhanced, leading to a reduction in pro-inflammatory cytokine leve
28 s and (2) a direct nucleophilic substitution leading to a stereoselective synthesis of the compounds
29 well as enhanced phospho-signalling within, leading to a submicron gradient of activated CtrA-P(19)
31 ) fused to the 3' end of RET tyrosine kinase leading to a TFG-RET fusion which transforms immortalize
32 hromatin accessibility and Smad3 DNA binding leading to a transcriptional program of RhoGEFs that fac
33 n in absolute efficiency exceeds 6 per cent, leading to a very high power conversion efficiency of mo
34 ll proportion of them are typically examined leading to a weak characterization of habitat connectivi
35 ve been vaccinated against common pathogens, leading to acquired pathogen-specific immunity with a ro
36 frequently harbor activating NRAS mutations leading to activation of MAPK kinase (MEK) and extracell
37 phate (cAMP)-dependent protein kinase (PKA), leading to activation of the PKA pathway, are the geneti
39 -specific ACT may trigger a bystander effect leading to additional T cell responses to nonviral tumor
41 factor kappa B-dependent metabolic pathway, leading to aerobic glycolysis and polarization of macrop
42 involves src-homology phosphatase activation leading to Akt-mediated nuclear exclusion of FoxO1 and c
43 in turn, reduces diastolic cytosolic Ca(2+), leading to alternations in diastolic cytosolic Ca(2+), R
44 lower in knockout mice but later increased, leading to an accumulation of significantly more macroph
45 O(2)-NH(2)-anti-IgG released FITC molecules, leading to an amplified fluorescence detection signal.
47 in 44% of the genome covered by >= 5 reads), leading to an average 14-fold increase in genome coverag
48 ral expansion and increased carrier density, leading to an exotic ferromagnetic to paramagnetic phase
50 r and enhanced processing of its transcript, leading to an imbalance in favor of AapA1 toxin expressi
52 most existing SCCA methods are unsupervised, leading to an inability to identify diagnosis-specific g
54 ncy blocks the activation of macroautophagy, leading to an increased abundance of BAX, a pro-death Bc
56 ty, electrically insulating single crystals, leading to anomalous transport properties well above cry
57 ing with respect to the exo-tert-butyl ones, leading to apparent association constants more than one
58 ation and K(+)-selective transport in hERG1, leading to arrhythmogenic phenotypes associated with lon
60 chieves these results with sparser sampling, leading to better index compression and competitive runt
61 atic environments in the region, potentially leading to bioaccumulation in fish and exposure to commu
62 te specific binding by the SHP2 active site, leading to blockade of RasGAP binding and optimal signal
63 germline mutations in telomere biology genes leading to bone-marrow failure, these data provide evide
65 lated by EP-4 and EP-1-dependent mechanisms, leading to breakdown of the pericyte-EC interaction.
66 pneumococcus and microaspiration prime AMs, leading to brisker responsiveness to both pneumococcus a
67 n fundamental understanding of all processes leading to catalytic activity, i.e., light absorption, c
68 , and cytoskeletal-microtubule organization, leading to cell cycle arrest, genotoxic stress, and inna
71 ganism instructs gene expression modalities, leading to changes in complex life history traits, such
72 t of pore water ions in opposite directions, leading to charge interactions that can affect the distr
73 high drug effluxion from liver cancer cells, leading to chemoresistance and a diminished chemotherape
74 thanolysis of the cyclic anhydride (+/-)-10, leading to chromatographically separable pairs of enanti
80 n addition to the gelatin-based compartment, leading to concurrent delivery and sequential release of
82 disturbed flow (DF) induces GCX degradation, leading to CTC homing to the endothelium, a first step i
83 affect protein folding and/or stabilization, leading to decreased WNT signaling and concomitant dysre
84 o be expected to cause competitive exclusion leading to deleterious changes in food web diversity.
85 s of direct virus-induced neural-cell damage leading to demyelination and axonal loss, which are path
87 change interactions in 2D monolayer regimes, leading to diluted magnetic semiconductor (DMS) material
88 d professional dimensions of patients' life, leading to disability which is essential to quantify as
89 ested in our patient-derived xenograft model leading to disease attenuation and prolonged survival.
90 extensively rewired among the three species, leading to distinct anatomical and morphological outcome
92 allografts through indirectly expanded nTreg leading to dominant tolerance without additional immunol
93 actions appear to reshape network structure, leading to dramatic community changes, including loss of
95 19 affects primarily the respiratory airways leading to dry cough, fever, myalgia, headache, fatigue,
96 ffect on non-tropical diversification rates, leading to dynamic young communities outside of the trop
97 s-221 disrupts both signaling and transport, leading to dysregulation of both the Has and Phu uptake
98 of all RP17 SVs was consistent with neo-TADs leading to ectopic retinal-specific enhancer-GDPD1 acces
99 s during the first cell cycle in the zygote, leading to embryos with non-mosaic restoration of the re
100 urn causes the destruction of alveolar walls leading to emphysema, making it potentially a valid targ
101 viously unrecognized transcriptional program leading to enhanced mRNA translation and resulting in an
105 of Pten gene through deletions and mutations leading to excessive pro-growth signaling pathway activa
106 Imbalances in the glutamatergic system, leading to excessive, toxic stimulation, have been assoc
107 oss-links in fibrillar elastin and collagens leading to extracellular matrix (ECM) stabilization.
109 nteraction with its target antigen beta2GP1, leading to fibrin clot formation due to exposure of anio
111 the full-length protein has been difficult, leading to focus on the C-terminal six cysteine domain (
112 ed because of the underlying pathophysiology leading to Fontan palliation, remodelling, or increased
117 cts on Wood Frog winter energy requirements, leading to geographically heterogeneous implications for
119 s indicates that anthropogenic modifications leading to habitat fragmentation and a higher genetic di
122 illicit drugs have been constantly growing, leading to heavy consequences for environment, human hea
125 alized surfaces was found to proceed rapidly leading to high grafting densities, while o-methylbenzal
126 L1 ligase, can inhibit the CRL2(VHL) complex leading to high HIF-1alpha protein levels and a metaboli
127 ponses to acute bacterial infection in mice, leading to high mortality due to sustained production of
129 ne oxides are highly polar functional groups leading to high solubility and metabolic stability but o
130 xibility, speed and uniformity at less cost, leading to high throughput and practical preclinical in
131 estion released the antioxidative compounds, leading to higher bioaccessibility of the breads enriche
133 soluble sugars, ascorbate, and TPC, together leading to higher germination and seedling growth in flo
134 A damage to hematopoietic stem cells (HSCs), leading to HSC depletion and dysfunction and the risk of
136 (IDH2) mutant-specific inhibitor enasidenib, leading to improved quality of life without a reduction
137 novel mutations, genes, and phenotypes, and leading to improvements in both diagnostic strategies an
138 al to rebalance disordered lipid metabolism, leading to improvements in nonalcoholic steatohepatitis
139 lation significantly enhances L-DOPA uptake, leading to increased DA release and GSIS reduction in an
140 kinase 1 (SIK1) stabilized the deacetylase, leading to increased expression of c-Myc, which in turn
141 actively infected astrocytes were inducible, leading to increased expression of viral proteins upon r
144 he inner mitochondrial membrane proton leak, leading to increased metabolism and changes in protein s
145 es, and upregulates the fabA and fabB genes, leading to increased production of unsaturated fatty aci
146 onate nanoparticles to enhance film porosity leading to increased surface area of colorimetric sensor
150 e +51 erythroid enhancer and TAL1 promoter-1 leading to inhibition of TAL1 expression in erythroid ce
151 flammation in both adipose tissue and ileum, leading to insulin resistance and impaired glucose and l
153 supervised and semi-supervised pretraining, leading to interesting insights into the precision/recal
154 al disease of recurrent sleep fragmentation, leading to intermittent hypoxia and subsequent diseases
155 ch is needed to better understand mechanisms leading to intussusception, particularly after rotavirus
156 olvement can compromise colonic blood supply leading to ischemic complications; however, few data exi
157 hole-genome duplication event in the lineage leading to L. japonica, which occurred after its diverge
158 aft rejection remain long-term complications leading to late graft failure in penetrating keratoplast
159 Long-term exposure-PM(2.5) is even worse, leading to leptin resistance, hyperphagia, and decreased
160 macrophages caused stellate cell activation, leading to liver injury, by a mechanism involving AQP3-m
162 albumin-binding domain was rapidly cleared, leading to lower tumor uptake (%ID/g) and decreased in v
164 en-carrier adducts in re-challenge reactions leading to mast cell degranulation and anaphylaxis is un
166 sites, causing a cascade of molecular events leading to microglia activation, perineural net degradat
167 eview the evidence on the complex mechanisms leading to MIF, as well as its contribution to systolic
168 of fragment ions and complementary ion pairs leading to more complete functional group characterizati
169 messenger RNA (mRNA) can act cooperatively, leading to more repression of the target mRNA than expec
173 eport that BRD4 phosphorylates MYC at Thr58, leading to MYC ubiquitination and degradation, thereby r
174 ementia commonly experience low food intake, leading to negative functional and nutritional consequen
175 oteasomal degradation, the precise mechanism leading to neurodegeneration in both sporadic and famili
176 loid (Abeta) on Cx43 expression and function leading to neuronal damage, underlying mechanisms by whi
178 nt cells, the control of plant cell division leading to nodule development, autoregulation of nodulat
180 es (e.g., carbon, nitrogen, and phosphorus), leading to nonlinear and interactive effects on particul
181 er time as compared with tufted cells (TCs), leading to odorant representations that were more distin
182 from binding of multiply charged ions, often leading to overall compaction of the protein depending o
184 ylated metabolites upon exposure to PCB-153, leading to oxidative stress, hemolytic anemia, and tumor
186 nociceptive output in pathologic conditions, leading to pain hypersensitivity.SIGNIFICANCE STATEMENT
188 alaria (CM), driven by a high parasite load, leading to parasite sequestration in organs and conseque
192 PHGDH and ubiquitinated PHGDH at lysine 330, leading to PHGDH degradation to suppress serine synthesi
194 oxins C3a and C5a, which activate mast cells leading to plasma extravasation, pain, and itching.
195 in unwanted cell or ribonuclease activation, leading to poor cell viability or RNA quality, which may
196 ooded soils encounter hypoxia or even anoxia leading to poor seed germination and crop establishment.
197 to ER-negative DCIS.com breast cancer cells, leading to populations enriched with highly plastic hybr
199 ct immune response networks for each strain, leading to predictions of relative virulence that are va
202 ymal hematoma triggers a series of reactions leading to primary and secondary brain injuries and perm
203 ver, the underlying intracellular mechanisms leading to product aggregate formation remain unknown.
204 -H bond activation, are triggered on demand, leading to product evolution in a controlled step-by-ste
205 ed diet in mice induced 2,8-DHA nephropathy, leading to progressive kidney disease, characterized by
208 2 QTLs showed higher alpha-amylase activity, leading to rapid starch degradation and increase in solu
210 r proportion of the ice overburden pressure, leading to reduced effective pressure and thus greater a
211 translation of specific mRNAs was remodeled leading to reduced production of collagens, loss of stru
214 rdered cyclic or bicyclic transition states, leading to remarkable levels of diastereoselectivity.
216 e that DYRK1A controls cyclin L2 expression, leading to restriction of HIV replication in macrophages
217 cyclin L2 amenable to cellular degradation, leading to restriction of HIV replication in macrophages
218 arger aberrations, with compensatory effects leading to robust tumour fitness maintained throughout t
220 -inhibitor AZD6738 (ceralasertib), in vitro, leading to selective cell death in ATM-deficient cells.
221 t a vulnerability to excess prooxidant loads leading to selective cell death, a therapeutically explo
222 plastic mast cells (MCs) in various tissues, leading to severe symptoms and organ damage (eg, cytopen
223 removed in extracted timber and eroded soil, leading to shifts in ecosystem functioning and community
224 ophagitis (EoE) has received the most focus, leading to significant advances in understanding of dise
225 complicated by frequent acute exacerbations leading to significant health care burden and impaired q
227 lved in the regulation of blood metabolites, leading to significant insights into the pathogenesis of
228 e major pathology and mortality to livestock leading to significant welfare and socio-economic issues
229 d decomposition in the adaptation scenarios, leading to similar SOC stocks under different climate ch
230 o a chiral nematic liquid crystalline phase, leading to solid-state nanostructured colored films upon
231 d through collateral phylogenetic branching, leading to spatial variability in the distribution of mo
232 hypoxia down-regulates kindlin-2 expression, leading to spindle abnormalities not only in the SH-SY5Y
235 ess is found to produce slip in soft grains, leading to strong dislocation pile-ups at boundaries wit
238 ther complex H-bonded networks most probably leading to supramolecular structures or non-specific int
239 nuous conduits for flow dictated by geology, leading to surface expression that can be greater or les
241 eased production of immunogenic micronuclei, leading to systemic tumor response with potential future
243 Here we propose a microscopic mechanism leading to the [Formula: see text]-symmetric effective m
244 , and new origin firing cannot be prevented, leading to the accumulation of DNA damage and cell death
246 y and sublimation rates were anticorrelated, leading to the conclusion that high densities of low-coo
247 n host cells that may guide immune responses leading to the concomitant damage associated with severi
248 io in a fluorescent Dulbecco's plaque assay, leading to the construction of a multireporter platform
249 pendently arising mutations in AAAD paralogs leading to the convergent evolution of the derived aldeh
250 es whether the two states have fused or not, leading to the creation of a W state of n + m - 2 electr
251 n be observed for cinnamic acid derivatives, leading to the delivery of the copper to the beta-positi
252 position of extracellular matrix components, leading to the deterioration of lung architecture and re
253 ocus on the computational level of analysis, leading to the development of mechanistic models at the
254 d resulting structure-activity relationship, leading to the discovery of a novel DBO, ANT3310, which
255 estigated this process on a synthetic scale, leading to the discovery of an Amadori-type rearrangemen
256 civermis from new material and the holotype, leading to the discovery of several new morphological fe
257 zation of, Kv4.2 at the pThr(607)-Pro motif, leading to the dissociation of the Kv4.2-DPP6 complex.
258 he transcription factors AP-1 and NF-kappaB, leading to the down-regulation of LINE-1 promoter activi
259 harbors the t(2;5) (p23;q35) translocation, leading to the ectopic expression of NPM-ALK, a chimeric
261 the tripeptide aldehyde protease inhibitors, leading to the formation of "pro-pyrazinones" featuring
262 ural phase changes of calcium phosphate (CP) leading to the formation of brushite, monetite and hydro
263 The reaction proceeds under mild conditions, leading to the formation of enantioenriched quaternary c
264 lds of the hippocampus, while simultaneously leading to the formation of integrated representations o
266 formational change in the expressed protein, leading to the generation of disease-related multichain
267 ormone transport to local tissue deformation leading to the generation of mechanical forces and the d
268 man semisynthetic phage library against RBD, leading to the identification of a high-affinity single-
269 g-KO mice was compared with that of WT mice, leading to the identification of similar abnormalities i
273 ay have been identified, enzymatic reactions leading to the production of these cis-isomers from tran
274 le-genome sequencing as a diagnostic tool is leading to the profiling of drug resistance to inform cl
275 s breaches in immune tolerance and barriers, leading to the promotion of immune-mediated diseases by
276 m the three fatty acid moieties of the TAGs, leading to the rapid and accurate identification of indi
277 r by co-selection of resistant strains, thus leading to the rapid emergence and subsequent spread of
278 ignaling by phosphorylating the adaptor ACT1 leading to the release of the essential ubiquitin ligase
279 c cell divisions at the fourth larval stage, leading to the retention of seam cell fate in both daugh
280 AP1 risk allele mediates enhanced autophagy, leading to the survival of autoreactive lymphocytes and
282 g probe (containing an electrochemical tag), leading to the variation of the electron transfer rate o
283 We reconstructed the evolutionary events leading to this gene cluster and found that its phylogen
284 onal response but also interact extensively, leading to transcriptional and epigenetic heterogeneity
288 gh the production of short-chain fatty acids leading to Treg cell development, and merits study as a
290 and elucidation of the biosynthetic pathway leading to triptolide are the prerequisite for heterolog
291 e division rates in a dose-dependent manner, leading to tumorous overproliferation when the canonical
293 omes persisted through cycles of glaciation, leading to unique assemblages in polar waters, rather th
294 he mode and rate of cleavage of NB moieties, leading to unpredictable limitations in control over sys
295 dysregulation of the cAMP signaling cascade, leading to upregulation of phosphodiesterase type 4 (PDE
296 es, shape within-patient seizure evolutions, leading to variable seizure pathways that may require ta
298 tems crosscut surrounding mountain aquifers, leading to water release that causes groundwater levels
299 commonplace in the beef and dairy industry; leading to welfare issues, negative environmental impact