ライフサイエンスコーパス: leak

1 49 patients had surgical complications (bile leaks).

2 ecretion, by increasing mitochondrial proton leak.

3 type 2 (RyR2)-dependent sarcoplasmic Ca(2+) leak.

4 al leak (LFL), punctate leak (PL) and vessel leak.

5 ve acute kidney injury (AKI) and anastomotic leak.

6 +) loading alone did not significantly raise leak.

7 ere excellent with low rates of paravalvular leak.

8 ility of Arg(208) in mutants exhibiting H(+) leak.

9 with enhanced oxygen consumption and proton leak.

10 on proteins at the breach, which repairs the leak.

11 lop calcium overload secondary to SR calcium leak.

12 cts, including cancers, immediately near the leak.

13 nit reveal sharp transitions resulting in Ca leak.

14 as deployed, 98.1% were implanted with <5-mm leak.

15 in spark frequency and spark-mediated Ca(2+) leak.

16 around increased risk of AKI and anastomotic leak.

17 3%) had previous surgery aiming to close the leak.

18 chnique for quantifying lymphatic valve back-leak.

19 ated, ectatic capillaries and late phase dye leak.

20 de, but at a higher arrhythmogenic SR Ca(2+) leak.

21 as placed in position with no intraabdominal leak.

22 in spark frequency and spark-mediated Ca(2+) leak.

23 ) was required to prevent neutrophil-induced leaks.

24 ul marker for active as well as past methane leaks.

25 dered when choosing a management pathway for leaks.

26 s and fluid extravasation through epithelial leaks.

27 ant difference was seen for flatus and minor leaks.

28 expanse and magnitude of stray gas migration leaks.

29 ffects include worsening cerebrospinal fluid leaks.

30 en by additional procedures for paravalvular leak (10%) and high-skirt neo-LVOT gradients observed be

31 This included early (7.8%) and delayed leak (2.0%), pelvic abscess (4.7%), anastomotic fistula

32 patients also had lower rates of anastomotic leak (2.7% vs 6.8%, P = 0.04), prolonged postoperative i

33 e were Clavien Dindo Grade 3b and 2 were 3a: leak 3 (2 JP,1 SE), fistula 4 (1 JP, 3 SE), small bowel

34 ng nonsurgical infections (23%), anastomotic leak (9.8%), other postoperative abnormal fluid from dra

35 t transport modes, ADP/ATP exchange and H(+) leak, AAC connects coupled (ATP production) and uncouple

36 that HIGD1 protein ablation enhances proton leak across the IMM.

37 Mechanistically, proton leak activates islet NGSIS independently of mitochondria

38 hese modifications significantly reduce dark leak activity and improve blue-light induction developin

39 NSAIDs were not associated with anastomotic leak (adjusted odds ratio 0.85, 95% CI 0.58-1.21, P = 0.

40 Placement of stents for management of leaks after bariatric surgery is common throughout the U

41 s who experienced anastomotic or staple line leaks after bariatric surgery, and then evaluated for us

42 ccessfully treat anastomotic and staple line leaks after bariatric surgery.

43 ed saline) or suppressor of site IQ electron leak, an inhibitor of superoxide production by complex I

44 NK2 in CaMKII-dependent arrhythmic SR Ca(2+) leak and a CaMKII-independent uptake exacerbates atrial

45 urgical complications, including anastomotic leak and abdominal abscess.

46 However, the contribution of vascular leak and consequent cardiac edema to the genesis of atri

47 was phosphorylated, resulting in ER calcium leak and cytosolic calcium elevation.

48 devices, but liquids in such devices tend to leak and evaporate.

49 e selectively inhibited RyR2-mediated Ca(2+) leak and exhibited higher potency and a distinct mechani

50 Anastomotic leak and its sequelae are dreaded complications followin

51 -induced lung damage, as measured by protein leak and lactate dehydrogenase (LDH) activity.

52 educed resistance to injury-induced vascular leak and leads to organ fibrosis.

53 Vessel leak and macular non-perfusion were associated with neur

54 oxification capacity, contributes to calcium leak and mitochondrial damage in the senescent myocardiu

55 This suggests that the H(+) leak and mitochondrial uncoupling could be dynamically c

56 w significantly higher CypD-dependent proton leak and NGSIS compared with lean mice.

57 SS-31 normalized the increase in proton leak and reduced mitochondrial ROS in cardiomyocytes fro

58 the absence of moderate/severe paravalvular leak and significant late frame fractures.

59 We observed 2 UC (ureteric leak and stenosis), 8 urinary tract infections, and 9 st

60 The biliary complications (leak and stricture) were higher in PLDRH group than in t

61 ardiographic data, 1 had a mild paravalvular leak and the rest had none/trace; 1 patient had mild pul

62 cyclophilin D-dependent mitochondrial proton leak and uncoupled mitochondrial respiration, leading to

63 cyclophilin D-dependent mitochondrial proton leak and uncoupling as a potentially novel subcellular m

64 Suppressor of site IQ electron leak and vehicle were administered during cardiopulmonar

65 ems due to both a larger estimated number of leaks and better characterization of the upper tail of t

66 quantify methane emissions from natural gas leaks and incomplete combustion while off, turning on or

67 ALI-induced HMGB1 leaks and is captured by arterial macrophages thereby al

68 wastewater facilities, superfund sites, and leaks and spills from industrial and municipal facilitie

69 ng oil and gas can reduce the possibility of leaks, and consequently, it can limit the extent of an e

70 Third, the proton leak appeared to take place through an inactive populati

71 e find mixed evidence that somatic call-sets leak appreciable numbers of germline variants, which is

72 Leaks are prevented by contractile actin filaments surro

73 All leaks are quantified to within 3.7 g min(-1) (12 scfh);

74 t in subsurface applications such as sealing leaks around wells.

75 Our results uncover the excessive proton leak as a novel mechanism of age-related cardiac dysfunc

76 data highlight inflammation-induced vascular leak as a potential factor in the development and progre

77 of our increased understanding of SR Ca(2+) leak as a shared Ca(2+)-dependent pathological mechanism

78 The system detects 100% of leaks, including leaks as small as 0.96 g min(-1) (3.1 scfh).

79 Fifty-four cases of chyle leak/ascites have been reported after LDN in literature

80 fferences in moderate or severe paravalvular leak at 30 days (2.0% vs 2.4%; absolute RD, 0.3% [95% CI

81 nt tube were significantly lower, frequently leaking at <1 cmH(2)O.

82 attenuated colitis progression as well as a leak barrier defect, albeit at the risk of intestinal ob

83 the rate of moderate-to-severe paravalvular leak became significantly higher among patients treated

84 to 14 eyes of 13 consecutive patients with a leaking bleb.

85 rgical (MICS) technique to repair late-onset leaking blebs after trabeculectomy.

86 A surgical technique to repair leaking blebs without incision or excision of conjunctiv

87 ), postpancreatectomy hemorrhage (PPH), bile leak, blood loss, reoperation, readmission, oncologic ou

88 nd thromboxane A(2)), which mediate vascular leak, bronchoconstriction, and effector cell chemotaxis.

89 ntified compound concentrations that reduced leak by > 50% but only slightly affected Ca(2+) release

90 = (0.74) 1.22 (2.02) ; P = .4), anastomotic leak (CACPR: 1.6%, non-CACPR: 2.0%; weighted OR = (0.54)

91 ed the hypothesis that VEGF-induced vascular leak can acutely increase atrial arrhythmia susceptibili

92 cretion, and hyperfiltration with glomerular leak can combine to increase albuminuria.

93 ne silent process, whereas necroptotic cells leak cellular contents that incite inflammation.

94 Here we investigate this essential leak channel and determined the structure of NALCN in co

95 ) mouse neurons, closure of the ATP synthase leak channel by mild depletion of its c-subunit or pharm

96 f dendritic membrane potential by the sodium-leak channel complex, and provide evidence supporting th

97 eld mole-rat exhibited overexpression of the leak channel NALCN (sodium leak channel, nonselective),

98 The sodium-leak channel NALCN forms a subthreshold sodium conductan

99 egulation of two potassium conductances: the leak channel Sandman imposes silence during waking, wher

100 in the 5' UTR of the potassium 2-pore domain leak channel Task3 mRNA.

101 nd Na(+) conductance in neurons is the Na(+) leak channel, non-selective (NALCN)(3,4).

102 expression of the leak channel NALCN (sodium leak channel, nonselective), ablating AITC detection by

103 odium-activated, high-conductance, potassium leak channel, SLO2.1, is expressed and active at the res

104 lts in an unusual voltage-dependent block of leak channels belonging to the TASK subfamily.

105 rtant in regulated local expression of Task3 leak channels that maintain K+ leak within neurons.

106 (Slo2), voltage-gated (SCN) Na(+) and Na(+) leak channels, nonselective (NALCN) channels, the Na K-A

107 e importance of accurate localization of the leaking chyle duct and its repair by endosuturing in a r

108 leaked dye (opening pressure) and ceased to leak (closing pressure), while the tube was held straigh

109 Therefore, ATP synthase c-subunit leak closure encourages development and attenuates autis

110 FMRP regulates leak closure in wild-type (WT), but not FX synapses, by

111 t atrial appendage closure, and paravalvular leak closure).

112 arding the potential for 3D printed molds to leak components into the PDMS that would, in turn, hampe

113 y) mouse have a mitochondrial inner membrane leak contributing to a "leak metabolism." In human Fragi

114 ot account for all possible sources of CH(4) leaks, contributing to uncertainty in the national CH(4)

115 ix (S4) of the Na(V)1.4 VSDs can result in a leak current through the VSD and hypokalemic periodic pa

116 hondrial depolarization, ischaemia-sensitive leak current, and time to K(ir) 6.2 opening.

117 consistent with myotonia, but also conduct a leak current.

118 ial or as a constitutively active epithelial leak current.

119 a G4-specific helicase DHX36, increasing K+ leak currents and membrane hyperpolarisation in HEK293 c

120 Persistently depolarizing sodium (Na(+)) leak currents enhance electrical excitability(1,2).

121 rens, TadNaC6, that conducts Na(+)-selective leak currents in vitro sensitive to blockade by both ext

122 Proton-leak currents were not increased in E818K.

123 These larger "leak currents" at V(rest) also lowered R(in) and produce

124 eneration by suppression of site IQ electron leak, decreased myocardial reactive oxygen species gener

125 transplant; however, she developed a biliary leak delaying the HSCT.

126 using data collected from an advanced mobile leak detection (AMLD) platform.

127 cal gas imaging (OGI) is a commonly utilized leak detection method in the upstream and midstream sect

128 nd make other adjustments that improve their leak detection rate, indicating that modifications of su

129 OGI survey experience significantly impacts leak detection rate: Surveyors from operators/contractor

130 rotocols and targeted training could improve leak detection rates overall.

131 was associated with more pronounced calcium leak, determined by confocal microscopy in cardiomyocyte

132 initially published online, the Paravalvular Leak Device (PLD; Occlutech) was incorrectly described a

133 Willebrand factor (VWF) resulted in vascular leaks during transmigration, indicating that platelets i

134 lish the pressure gradient at which the tube leaked dye (opening pressure) and ceased to leak (closin

135 (2 early, 1 control) and a cystic duct stump leak (early).

136 they are bulky and difficult to miniaturize, leak electrolyte to the medium, lose the ability to defi

137 describe and classify phase transitions and leak emergence.

138 significant unaccounted-for sources of CH(4) leaks, especially over cities.

139 nsitive ATG-out) vectors virtually eliminate leak expression.

140 fficacy of stent placement for postoperative leak following bariatric surgery.

141 The onset of bleb leak following trabeculectomy ranged from 7 months to 16

142 nactivation, of endothelial Tie-2 results in leak formation in postcapillary venules of the inflamed

143 Leak-free and pad-free continence rate was 90% (27 of 30

144 In modeling leak frequency, we find a clear interaction between pipe

145 tions were pneumonia (21%), esophago-enteric leak from anastomosis, staple line or localized conduit

146 tions were pneumonia (12%), esophago-enteric leak from anastomosis, staple line or localized conduit

147 Vessel leak from barrier dysfunction, and non-perfusion were no

148 ticipants results in significant information leak from differentially private results of complex quer

149 on, and partly results from increased Ca(2+) leak from sarcoplasmic reticulum stores via dysregulated

150 evidence that VLF transmitter emissions that leak from the Earth-ionosphere waveguide are primarily r

151 failing heart, the elevated diastolic Ca(2+) leak from the sarcoplasmic reticulum can be normalized b

152 resulting in a pathological diastolic Ca(2+) leak from the SR that both triggers arrhythmias and impa

153 h stabilize RYR2 channels and prevent Ca(2+) leak from the SR, are undergoing investigation in clinic

154 ative damage by clearing hemoglobin that has leaked from red blood cells and also restricts the avail

155 c framework could capture most of the Pb(2+) leaked from the degraded perovskite solar cells by formi

156 pective of DNA sequence, therefore, self-DNA leaked from the nucleus or mitochondria can also serve a

157 the postulated source of the leakage was (1) leaks from a contaminated water tank that occurred from

158 We also report that the frequency of methane leaks from the local distribution system ranges between

159 However, under abnormal conditions, Ca leaks from the SR, decreasing heart contraction amplitud

160 om abandoned wells; some were reported to be leaking gas several decades after they were permanently

161 rhagic contusions are associated with iodine leak; however, quantification of leakage and its importa

162 evealed that the specific distribution of I (leak), I (ir), I(m) , and I (h) was sufficient to explai

163 Prolonged air leak in 141, deep venous thrombosis in 64, Atrial fibril

164 increased state 4 respiration linked proton leak in both neonatal and young adult mice while complex

165 ic conditions, profoundly increased vascular leak in both white and gray matter during CMH, and this

166 roalbuminuria screening to detect glomerular leak in diabetes.

167 thermogenic respiration due to futile proton leak in Fmr1 KO mitochondria caused by coenzyme Q (CoQ)

168 Both compounds also decrease RyR1 Ca(2+) leak in human skinned skeletal muscle fibers.

169 n endothelial hyperpermeability and vascular leak in mice, and NS1 vaccination confers antibody-media

170 found that CMH triggered transient vascular leak in spinal cord blood vessels, particularly in white

171 we show direct evidence of increased proton leak in the aged heart mitochondria.

172 duction for foam use much more CFC-11 may be leaked in the future.

173 We estimate that there are 630,000 leaks in U.S. distribution mains, resulting in methane e

174 g; 3.3% rate of moderate-severe paravalvular leak) in the extra-large annulus, without differences co

175 The system detects 100% of leaks, including leaks as small as 0.96 g min(-1) (3.1 s

176 Ozone premature mortalities away from the leak increased by <1.

177 Our analysis leveraged data on >4000 leak indications found using AMLD, combined with utility

178 , the JNK2-enhanced SR Ca(2+) uptake limited leak-induced reduction in SR Ca(2+), normalizing Ca(2+)

179 on (V6A) in a motif associated with vascular leak induction yields a fully active, second-generation

180 itatively how hyperfiltration and glomerular leak interact to promote albuminuria.

181 disruption and allow peripheral cytokines to leak into the CNS, exacerbate the gliosis, and result in

182 , and carboxyl ester lipase (CEL), which may leak into the visceral fat or systemic circulation durin

183 uli and sinusoids by which bile constituents leaked into blood.

184 red variants may represent germline variants leaked into somatic call sets.

185 protein (Hp) scavenges toxic hemoglobin (Hb) leaked into the bloodstream from erythrocytes.

186 vapors of a variety of liquid reagents to be leaked into the trap traveling wave ion guide of the ins

187 ter for irrigation and livestock; wastewater leaked into this aquifer may possibly contaminate that f

188 g pancreatitis, unlike diverticulitis, PNLIP leaking into visceral adipose tissue can cause excessive

189 ures (e.g. 0.5-10cmH(2) O) and pressure back-leak is extrapolated from calibrated, pressure-driven ch

190 ully monomeric protein with reduced vascular leak, is a second-generation diphtheria-toxin-based fusi

191 inase II)-dependent JNK2 action in SR Ca(2+) leak, JNK2-driven SERCA2 function was CaMKII independent

192 TRAAK contributes to the 'leak' K(+) current in mammalian nerve fiber conduction b

193 tures; however, they take longer to seal and leak larger volumes before sealing.

194 ational stability and minimizing potentially leaked lead (Pb(2+)) ions are two challenges that are ye

195 ates the inner mitochondrial membrane proton leak, leading to increased metabolism and changes in pro

196 bstruction Response (POOR) in which alveolar leak leads to surfactant dysfunction and increases local

197 induced retinopathy, similarly sized lesions leak less in mutant mice, separating regulation of perme

198 es of retinal leakage were seen: Large focal leak (LFL), punctate leak (PL) and vessel leak.

199 al respiratory capacities (day 8) and proton-leak linked respiration (day 14) with 12 muM ddC.

200 r advantages including simpler design, lower leak, lower cost, and higher signal-to-background ratio.

201 inhibitor of RyR2-mediated diastolic Ca(2+) leak, making it a molecular tool to investigate the ther

202 cs were statistically similar when comparing leaks managed with stents to those treated with reoperat

203 Results suggest that the Aliso Canyon leak may have increased the mixing ratios of multiple em

204 Fluorescein leak, measured by CLE, improved only in those allocated

205 Proton leak-mediated NGSIS is conserved in human islets and is

206 gent-free membrane to minutes or less in the leaking membrane.

207 drial inner membrane leak contributing to a "leak metabolism." In human Fragile X syndrome (FXS) fibr

208 0 without; defined as >5 d postoperative air leak; n = 189 (8.3%)]; probability estimates for propens

209 These breaches, or leaks, occur as cell boundaries elongate, correspond to

210 Anastomotic leak occurred in 16% of patients, 2% required reoperatio

211 en h > 0 and beta >beta(*), and a disordered leak occurs when beta <beta(*) and h is not too negative

212 e of device-related thrombus, and peridevice leak of <=5 mm.

213 h in glioblastoma cells characterized by the leak of bulk water from the cell membrane.

214 ndrial DNA damage in SMCs and the subsequent leak of DNA to the cytosol activated STING signaling, wh

215 fast-vacuolar channels that mediate the back-leak of Na(+) into cytosol and, if not regulated tightly

216 oton pumping by complex IV (CIV) or enhanced leak of protons across the IMM.

217 f extremely high discrimination coupled to a leak of the driving ion, akin to proofreading.

218 nk that occurred from 2013 to 2014, or (2) a leak of tritium that had spread widely over an impermeab

219 al gas equipment configured with intentional leaks of controllable rate.

220 patients (0.3%) required intervention for a leak, of whom 275 (24%) were treated with an endoscopica

221 Subsurface natural gas release from leaking oil and gas wells is a major environmental conce

222 This study estimates the impacts of the leak on transient weather, climate, air quality, and hea

223 up to <0.15 m, whereas the human body alone leaks only up to ~0.01 m, compared to >5 m detection ran

224 thout affecting intrinsic ryanodine receptor leak or phosphorylation.

225 ence (OR = 0.43, P = 0.001), and anastomotic leak (OR = 0.53, P < 0.001).

226 nfection (OR = 0.59, P = 0.005), anastomotic leak (OR = 0.53, P = 0.002).

227 onary oedema, and the device malfunctioning, leaking, or dislodging.

228 so be completely lost or the information can leak out of the computational space(10-14).

229 ides a mechanism to prevent absorbed Mn from leaking out of the stele.

230 that a significant amount of the HOX formed leaks out as free HOX.

231 probe occurs via recycling as it perpetually leaks out of the ciliary OS.

232 0.596), conduit necrosis (P = 0.524), chyle leak (P = 0.427), pneumonia (P = 0.548), and respiratory

233 dard and prolonged TTS regarding anastomotic leak (P = 0.596), conduit necrosis (P = 0.524), chyle le

234 th a higher rate of significant paravalvular leak (P=0.004), second valve implantation (P=0.013), and

235 study was to determine whether prolonged air leak (PAL) is associated with postoperative morbidity an

236 Endothelial dysfunction and vascular leak, pathogenic hallmarks of severe dengue disease, are

237 eveal unsuspected links between the pore and leak pathways of intestinal permeability and immune resp

238 as a composite endpoint of early or delayed leak, pelvic abscess, anastomotic fistula, chronic sinus

239 distribution system ranges between 4 and 22 leaks per 100 km of roadway in downtown Toronto, which i

240 were seen: Large focal leak (LFL), punctate leak (PL) and vessel leak.

241 ce of postoperative pancreatic fistula, bile leak, postpancreatectomy hemorrhage (all ISGPS grade B/C

242 e of a chimeric strain expressing a vascular leak-potent NS1.

243 ite higher PM(2.5) in Los Angeles due to the leak, premature mortalities there were more ambiguous, r

244 However, with JNK2-CaMKII-driven SR Ca(2+) leak present, the JNK2-enhanced SR Ca(2+) uptake limited

245 , inability to close developmental c-subunit leak prevents stimulus-dependent synaptic maturation.

246 Furnaces are the most leak-prone of appliances, contributing to 0.14% of total

247 copy, we demonstrate how maternal pheromones leak-proof the egg, consequently concealing it from cons

248 Nano-structured shunts were durable, leak-proof, and demonstrated biocompatibility and patenc

249 es a nonconducting closed state, the channel leaked protons.

250 There was no difference in anastomotic leak rate (8.1% HL vs 6.7% LL).

251 The anastomotic leak rate in patients who received an anastomosis was 4.

252 There was no difference in leak rate or mortality.

253 .01), 30-day mortality was 1.5%, anastomotic leak rate was 3.1%.

254 e related to functional outcome, anastomotic leak rate, and oncological adequacy.

255 to lower SR Ca load because of the higher Ca leak rate.

256 rgeons who over-rated their skill had higher leak rates for more complex procedures.

257 tom quartiles were similar after SG, however leak rates were higher with GBP among surgeons who over-

258 abatement costs are dependent on natural gas leak rates, but consistently indicate that all-electric

259 nt difference was seen in SSI or anastomotic leak rates, but there was a significant reduction in 30-

260 g from the use of natural gas and under high leak rates.

261 y on catalytic control and must be robust to leak reactions.

262 s of SR operation generating the abnormal Ca leak remain unclear.

263 >=3 complications, LOS, POPF, DGE, PPH, bile leak, reoperation, readmission, or oncologic outcomes be

264 Michael's Hospital for bleb leaks repaired with MICS from 2012 to 2017.

265 is mechanism, suppressor of site IQ electron leak, represents a potential, practical therapy for impr

266 Both cold environments also increased leak respiration and decreased phosphorylation efficienc

267 normoxia or hypoxia increased mitochondrial leak respiration and decreased phosphorylation efficienc

268 iration (both for complex I and complex II), leak respiration and oxidative phosphorylation coupling.

269 the channel, blocked the pathological proton leak, restored rates of protein synthesis during synapto

270 The leak size required to achieve a 90% probability-of-detec

271 ammatory cytokines known to promote vascular leak, such as vascular endothelial growth factor A (VEGF

272 tients with severe CRS may develop capillary leak syndrome and disseminated intravascular coagulation

273 Capillary leak syndrome was reported in 19% of the patients and wa

274 bumin loss in urine, and alleviate capillary leak syndrome.

275 cal laser photocoagulation was used to treat leaking telangiectasias and to limit further ERD expansi

276 infection, wound dehiscence, and anastomotic leak than no preparation and a lower rate of SSI than AB

277 to testing detected 1.7 (1.5-1.8) times more leaks than surveyors who had completed fewer surveys.

278 ion and promotes renal interstitial vascular leak, thereby partially contributing to the pathogenesis

279 and determining the degree of pressure back-leak through an intact valve in pressurized, single-valv

280 llary barrier, triggering pulmonary vascular leak thus inducing acute lung injury (ALI).

281 underlying changes in membrane potential to leak to 'coupled' partners, dampening neuronal excitabil

282 tructure suggest many small beyond-the-meter leaks together contribute to large emissions.

283 omerular filtration rate, glomerular protein leak, tubular protein uptake via endocytosis and PT wate

284 o known as KCNK5) channels generate pH-gated leak-type K(+) currents to control cellular electrical e

285 no statistical differences in intraabdominal leak, unplanned reoperation, myocardial infarction, or i

286 ltaneous direct measurement of pressure back-leak using a servo-null micropressure system.

287 ires free fatty acids and resembles the H(+) leak via the thermogenic uncoupling protein 1 found in b

288 using task progression scores, error scores, leak volumes, and knot tensile strengths.

289 Complete resolution of the bleb leak was observed following surgery in all cases.

290 Recurrent bleb leak was reported in 1 patient 2 years following initial

291 tochondrial membrane potential, and electron leak, we found minimal evidence of oxidative insufficien

292 dent rates of leakage and GHG emissions from leaking wells.

293 mbosis, device dislodgement, or a new device leak were observed.

294 mal respiration, reserve capacity and proton leak, whereas activation of mTORC1 had the opposite effe

295 Suppressor of site IQ electron leak, which inhibits complex I-dependent reactive oxygen

296 clusters have a higher threshold and a lower leak, which tends to increase SR Ca load.

297 Our theory predicts that a synchronized Ca leak will occur when h > 0 and beta >beta(*), and a diso

298 Future leaks will also likely have impacts.

299 unchanged in POAF despite greater SR Ca(2+)-leak, with a trend towards increased SR Ca(2+)-ATPase ac

300 sion of Task3 leak channels that maintain K+ leak within neurons.