ライフサイエンスコーパス: leaky

1 ort in intestinal epithelia, rendering them "leaky".

2 e imaging and found that the tumors were not leaky.

3 es to alleviate resurgence when vaccines are leaky.

4 such that HR is chemically inducible and non-leaky.

5 when vessels are uncompressed, but not very leaky.

6 giogenesis, but the newly formed vessels are leaky.

7 ted to the propensity of a nanocarrier to be leaky.

8 g off ABA signal transduction, to counteract leaky ABA signal transduction caused by "monomeric" PYL/

9 eta-band (10-30 Hz) signals, resulting in a "leaky" accumulation process that conferred greater behav

10 g models that forms decisions by acting as a leaky accumulator with non-absorbing bounds.

11 The neovessels in alpha(M)(-/-) mice were leaky and immature because they lacked smooth muscle cel

12 : In sepsis, quiescent blood vessels become leaky and inflamed by mechanisms that are incompletely u

13 The blood vessels of cancerous tumours are leaky and poorly organized.

14 he circumstances under which the gut becomes leaky and to discover bacterial metabolites that promote

15 er of the target membrane so that it becomes leaky and unable to form a clean fusion pore.

16 Vessels in the kindlin-2(+/-) mice were leaky, and BM transplantation from kindlin-2(+/-) to WT

17 cular function by exacerbating nonproductive leaky angiogenesis.

18 , but has been difficult to generate because leaky antigen expression in the thymus results in centra

19 many aminoacyl-tRNA synthetases, in which a leaky AUG start codon is followed by a strong Kozak cont

20 Genetic ablation of Mfsd2a results in a leaky BBB from embryonic stages through to adulthood, bu

21 , WBCs populated the perivascular space of a leaky BBB.

22 Many livestock and human vaccines are leaky because they block symptoms but do not prevent inf

23 As the tumors were not leaky before BBB disruption and there were no responders

24 e blockade of B-cell differentiation, with a leaky block in T-cell differentiation resulting in an ol

25 non-tortuous blood vessel formation and non-leaky blood vessels by 10 days post-stroke.

26 This inherently disorganised collection of leaky blood vessels contribute significantly to suboptim

27 Edema stemming from leaky blood vessels is common in eye diseases such as ag

28 Architecturally defective, leaky blood vessels typify pathologic angiogenesis induc

29 Microglial repair of leaky blood vessels was blocked by a peptide that inhibi

30 sequent stages there were fewer capillaries, leaky blood vessels, disrupted endothelium - perivascula

31 orm transient openings and closings at these leaky blood vessels.

32 eter in the developing brain, resulting in a leaky blood-brain barrier (BBB).

33 ampus, and is essential for development of a leaky blood-brain barrier after seizures.

34 A leaky blood-brain barrier has long been implicated in co

35 tified that claudin-1 is highly expressed in leaky brain microvessels.

36 te promotes and sustains an up-regulated and leaky - but N-limited - internal N cycle.

37 ng Ca(2+) signaling in spines by acting as a leaky Ca(2+) integrator with the time constant of severa

38 m the channel domain, leaving an unregulated leaky Ca(2+) pore.

39 We assumed that vaccine effect was leaky, calculated mVE as 1 minus the Mantel-Haenszel rel

40 rization dynamics in myocytes by acting as a leaky cap at thin filament pointed ends.

41 A leaky-capacitor model related to the dielectric properti

42 M treatment, no ultrastructural evidence of leaky capillaries in the brain was observed in the septi

43 to the formation of abundant microaneurysms, leaky capillaries, and retinal hemorrhages.

44 mpaired lymphatic function, characterized by leaky capillary lymphatics and decreased collecting vess

45 al infections can induce a septic state with leaky capillary syndrome, disseminated coagulopathy, and

46 vasculature including endothelial cell lined leaky capillary vessels along with 3D solid tumors.

47 c paralysis (hypoPP; usually associated with leaky cation channels in muscle cells).

48 al surface with masked surface rodlet layer, leaky cell wall allowing the deposition of proteins on t

49 to result from malformed vascular walls with leaky cell-to-cell junctions.

50 er carbon and energy metabolism, but only in leaky cells with a proton permeability equivalent to fat

51 s that simulate exercise, consistent with a "leaky" channel.

52 studies showed that LDH and GAPDH can form a leaky channeling complex only at the limiting NADH conce

53 utations introduced into RyR2 that result in leaky channels and cause exercise induced polymorphic ve

54 , and PKA hyperphosphorylated, resulting in "leaky" channels in failing hearts.

55 a fractured containment regime behaves as a leaky chemical reactor regarding its effect on isotopic

56 ition, there is substantial depletion of the leaky claudin, claudin-2, but not other tight junction c

57 Furthermore, leaky claudins have been shown to be required for epithe

58 sensitive but nonspecific in identifying FA leaky CNV.

59 udin-3-/- mice revealed dedifferentiated and leaky colonic epithelium, and developed invasive adenoca

60 rarchical evidence integration, hierarchical leaky competing accumulation (HLCA), and probabilistic e

61 inding of peripheral membrane proteins and a leaky connecting cilium diffusion barrier.

62 e electrotonic dendritic structure causing a leaky distal dendritic compartment with correspondingly

63 cholangitis due to regurgitation of BA from leaky ducts.

64 e representing a novel target for preventing leaky endothelial barrier syndrome.

65 ss fibers, resulting thereby in formation of leaky endothelial barrier.

66 es paracellular Na(+) and water transport in leaky epithelia and alters cancer cell proliferation.

67 mmatory bowel disease, are associated with a leaky epithelial barrier, resulting in excessive exposur

68 elial barrier integrity in AR, maintaining a leaky epithelial barrier.

69 with watery diarrhoea, which was caused by a leaky epithelium and reduced bile re-absorption in the i

70 eins, as its expression is restricted to the leaky epithelium in vivo and correlates with epithelial

71 otic activities of these compounds against a leaky Escherichia coli strain and the wild-type strain r

72 tringent catabolite repression, resulting in leaky expression of genes that are not required for grow

73 oic acid receptor alpha, enabling a mild and leaky expression of proinflammatory mediators.

74 We found that this loop can reduce leaky expression of target genes in the presence of gluc

75 Leaky expression resulted in two levels of PH-Tau: low b

76 ) tCRISPRi shows significantly less than 10% leaky expression.

77 ced editing capacity, off-target effects, or leaky expression.

78 liquid filaments are central to dripping of leaky faucets, inkjet drop formation, and raindrop fragm

79 ature, such as "dripping ants" or drops from leaky faucets.

80 hoton component of the condensate boosts the leaky field beyond the boundary of the ZnO microcrystals

81 ay damage the intestinal epithelial barrier (leaky-flux diarrhea) and/or alter chloride ion secretion

82 by rendering the sarcoplasmic reticulum (SR) leaky for Ca(2+).

83 We develop a model where organisms perform 'leaky' functions that provide both private and public be

84 We ruled out leaky fusion as a mechanism of release by including 2 mo

85 des cross BMP-enriched membranes by inducing leaky fusion between them.

86 e properties (e.g., low permeability and non-leaky fusion capability) for further development in lipo

87 the G13A fusion domain mutant produces a new leaky fusion phenotype.

88 The relation of 'leaky' fusion to the observed prefusion structures is di

89 Genetic autopsies have detected "leaky" gain-of-function mutations in the ryanodine recep

90 tellar absorption lines for identifying such leaky galaxies.

91 Accordingly, we propose a "leaky gate" model in which Grp(+) neurons transmit both

92 s to polar amino acids produce channels with leaky gates that conduct ions in the resting state.

93 entials, consistent with the proposal that a leaky gating pore in R669H channels triggers attacks, wh

94 LplA imparts DeltalipB strains with a 'leaky' growth phenotype on aerobic glucose minimal mediu

95 r is utilized to demonstrate a novel type of leaky-guided acoustic wave that couples simultaneously t

96 The data suggest that a leaky gut barrier is linked with liver steatosis and cou

97 Such 'leaky gut' conditions result in systemic inflammation, o

98 resenting increased intestinal permeability (leaky gut) such as depression, showing a potential thera

99 Psychosocial stress, diet, obesity, a leaky gut, and an imbalance between regulatory and pro-i

100 plication, it is incapable of restoring the "leaky gut," which poses an impediment for HIV cure effor

101 cient (Nr1i2(-/-)) mice showed a distinctly "leaky" gut physiology coupled with upregulation of the T

102 Prolonged morphine treatment results in a "leaky" gut, predisposing to colonic inflammation that is

103 observed that background fluorescence due to leaky H2B-FP expression, occurring in all H2B-FP transge

104 blood vessels in tumours by making them less leaky--have been shown to improve the delivery and effec

105 The drug cessation caused highly leaky hepatic vasculatures permit tumour cell intravasat

106 In laser-irradiated tumors, the use of leaky HPPH liposomes resulted in improved doxorubicin bi

107 becomes more stringent if vaccine action is leaky (ie, the susceptibility of each vaccine recipient

108 ods from percolation theory we consider both leaky immunity, where all previously infected individual

109 e of inducing BTB remodeling, making the BTB leaky in studies in vivo Furthermore, NC1 domain peptide

110 ight junction disruption, making the barrier leaky), in the testis in vivo We report our findings tha

111 arsupials is characterized by exclusive, but leaky inactivation of the paternally derived X chromosom

112 ise rather than by non-linearities; and 5) a leaky integrate and fire model reproduces these results

113 nts are conducted in a multilayer network of leaky integrate-and-fire (LIF) spiking neuron models.

114 rall, the spiking activity of the fractional leaky integrate-and-fire model deviates from the spiking

115 Here we developed and analyzed a fractional leaky integrate-and-fire model in which the exponent of

116 , but with a form distinct to the point-like leaky integrate-and-fire model; a non-monotonic dependen

117 Similarly, in exponential leaky integrate-and-fire models using a shallow voltage-

118 random crossing of the firing threshold by a leaky integrate-and-fire neuron model, and (iii) assumin

119 SOC behavior in networks of non-conservative leaky integrate-and-fire neurons with short-term synapti

120 , we use the master equation for generalized leaky integrate-and-fire neurons with shot-noise synapse

121 the basic neuron functionalities: activity, leaky integrate-and-fire, volatility and rate coding.

122 of weight dynamics in a simple system with a leaky-integrate-and-fire neuron with a random spike-trai

123 t a simplified, sparse inhibitory network of Leaky-Integrate-and-Fire neurons can reproduce some key

124 We found that a dynamic urgency signal and leaky integration, in combination with two independent f

125 r models predict that the parameters of this leaky integrator are finely tuned through the interactio

126 ehavior is in close agreement with a bounded leaky integrator model.

127 presence of phosphatase, CaMKII behaves as a leaky integrator of calcium signals, a result that has b

128 assuming an internal state that behaves as a leaky integrator of stimulus exposure.

129 A computational model using coupled leaky integrator units with biophysically plausible assu

130 at sodium channels can implement a molecular leaky integrator, where the input signal is the membrane

131 These leaky integrators encode the Laplace transform of their

132 These vectors are leaky integrators that could be constructed from a popul

133 ce unfolding in time is encoded via a set of leaky integrators.

134 we demonstrate that sea urchin larvae have a leaky integument.

135 ons support conformational flexibility and a leaky interface.

136 ed serum zonulin levels are accompanied by a leaky intestinal barrier, dysbiosis and inflammation.

137 decrease in transepithelial resistance and a leaky intestinal epithelium that was determined by in vi

138 Compressor vents, leaky isolation valves, reciprocating engine exhaust, an

139 found that when electrode damage makes cells leaky it could profoundly distort cellular excitability

140 ly as immediate early (alpha), early (beta), leaky late (gamma1), and true late (gamma2), where viral

141 revealed that UL91 protein is expressed with leaky-late (gamma1) kinetics, localizes in the nucleus w

142 ges, swollen axons and terminals, as well as leaky-like DiI-labeled terminals, were observed in long-

143 g pathway is a critical factor in persistent leaky lung microvessels and edema formation in the disea

144 y with scale-free properties--is examined in leaky Markovian networks.

145 opting an approach suitable for electrically leaky materials as MAPbI3, we show here ferroelectric hy

146 2) Strains from both species manifesting the leaky melanin phenotype had reduced chitosan content, wh

147 spectroscopy of representative isolates and "leaky melanin" mutant strains from each species complex

148 ld-type fusion domain promotes efficient non-leaky membrane fusion, we asked whether different angles

149 cannot be explained by classic quasi-steady "leaky membrane" models, which always predict instability

150 Pumping protons across leaky membranes offers no advantage, even when permeabil

151 Dclre1c(leaky) mice also had inflammatory symptoms, including wa

152 Dclre1c(leaky) mice present with a complete blockade of B-cell d

153 vironments, which are characterized by dense leaky microvasculature and acidic extracellular pH (pHe

154 mas, despite the presence of heterogeneously leaky microvessels, dense extracellular matrix and high

155 ctions) with different polarizations - a 'bi-leaky' mode.

156 ographic video displays based on anisotropic leaky-mode couplers, which have the potential to address

157 not superior in performance to conventional leaky-mode fiber optic silica HWGs having similar optica

158 elies on imaging multimode interference from leaky modes along a multimode tapered optical fibre, res

159 d, allowing for the simulation of radiative (leaky) modes.

160 In the leaky mterf6-1 mutant, a defect in photosynthesis is ass

161 affect this process - on the gut flora, the 'leaky' mucosal membrane and endotoxin coupled lipid abso

162 to our knowledge for the first time, that a leaky mutation in the Arabidopsis (Arabidopsis thaliana)

163 sfunction of RyR2 channels in the brain via 'leaky mutations' can result in mild developmental delay

164 ridity and vegetation interact to maintain a leaky N cycle during periods when plant N uptake is low,

165 it of tumor cell dissemination, due to their leaky nature and secretion of tumor-recruiting factors.

166 fer of two particular types of noise: basal (leaky) network activity and cell-to-cell variability in

167 Previous studies identified a role of leaky neuronal RyR2 in posttraumatic stress disorder (PT

168 The biophysical mechanisms by which these leaky neurons maintain their excitability are not unders

169 contact with p15/ARPC5 led to unregulated ("leaky") nucleation in the absence of WASp.

170 cin-sensitive Escherichia coli strain with a leaky outer membrane, we identified a mutant with increa

171 ctivity, which might result from one or more leaky pal mutant genes or from other unknown PAL genes.

172 bandgap (i.e., 1.1-3.8 eV), the electrically leaky perovskite oxides generally lose piezoelectricity

173 Thus, one cause of the leaky pipeline in biomedical research may be the exclusi

174 ology, and policy-making has focused on the "leaky pipeline" problem: the observation that fewer wome

175 omen to pursue research careers to stop the 'leaky' pipeline.

176 ctin polymerization, thus making leiomodin a leaky pointed-end cap.

177 rupt this protective barrier by formation of leaky pores.

178 provide antibiotic-sensitive neighbors with leaky protection from drugs, as shown both in vitro and

179 ducible promoters cause background HR due to leaky protein expression, preventing the generation of r

180 ovides partial protection in all vaccinees ("leaky") rather than complete protection in a subset of v

181 nm nanoparticles after they extravasate from leaky regions of the tumor vasculature and are exposed t

182 rapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enh

183 and exhibit enhanced accumulation around the leaky regions of the tumor vasculature, but their large

184 translation is regulated by a combination of leaky ribosomal scanning and reinitiation, and that the

185 se a model in which AUGs 1-4 are accessed by leaky ribosomal scanning, with sORF2 repressing synthesi

186 rillation (AF) risk has been associated with leaky ryanodine receptor 2 (RyR2) Ca release channels.

187 cating that these phenotypes are caused by a leaky ryanodine receptor.

188 errant diastolic calcium (Ca) release due to leaky ryanodine receptors (RyR2s) has been recently asso

189 Targeting AF caused by leaky RyR2 Ca channels with R-propafenone may be a more

190 cause or inhibit SR Ca2+ leak, we found that leaky RyR2 channels result in mitochondrial Ca2+ overloa

191 signaling, and altered Ca(2+) signaling via leaky RyR2 channels.

192 Leaky RyR2 could be a therapeutic target for treatment o

193 Here we find that a human leaky RyR2 mutation, R176Q (RQ), alters neurotransmitter

194 uting to premature death in individuals with leaky RYR2 mutations.

195 We discovered that CPVT patients with mutant leaky RyR2 present with glucose intolerance, which was h

196 mpaired SR Ca2+ reuptake that conspires with leaky RyR2 to deplete SR Ca2+.

197 Our data demonstrate that leaky RyR2, but not IP3R2, channels cause mitochondrial

198 -dependent protein kinase (CaMKII)-dependent leaky RyR2.

199 he arrhythmias induced by a CaMKII-dependent leaky RyR2.

200 2.6 (also known as calstabin2), resulting in leaky RyR2.

201 As these mutations result in a "leaky" RyR2 channel, we exploited them to assess RyR2 ch

202 These leaky RyR2s contribute to depletion of Ca2+ from the SR,

203 Pathogen contamination from leaky sanitary sewers poses a threat to groundwater qual

204 (MH) susceptibility has been attributed to a leaky sarcoplasmic reticulum (SR) caused by missense mut

205 o neuroendocrine stress, with sensitized and leaky sarcoplasmic reticulum Ca(2)(+) release as a compe

206 ranslation induction is governed by means of leaky scanning and not re-initiation.

207 tion of the major ORF of IFRD1 involves both leaky scanning at the upstream AUG codon and re-initiati

208 is responsive to stress conditions and that leaky scanning can induce ORF translation by bypassing p

209 ffects 40S occupancy of eIF3, and produces a leaky scanning defect indicative of a deregulation of th

210 Our data indicate that leaky scanning like re-initiation is responsive to stres

211 upt their interactions with the RRM increase leaky scanning of an AUG codon.

212 Leaky scanning past the uORFs facilitates ORF35 expressi

213 ey tryptophan residues results in the severe leaky scanning phenotype partially suppressible by overe

214 translation of uORFs on uORF1 and attenuate leaky scanning that bypasses uORFs.

215 translation initiation by re-initiation and leaky scanning using downstream AUG codons.

216 de of translational initiation regulation is leaky scanning, and this regulatory process has not been

217 he downstream P gene translated by ribosomal leaky scanning.

218 A leaky-scanning model of translation based on Kozak trans

219 ps5 that reduced bulk initiation, conferred 'leaky-scanning' of AUGs; and lowered initiation fidelity

220 entified in patients with Omenn syndrome and leaky SCID as a result of hypomorphic RAG mutations.

221 16, 32 patients with NBS-identified SCID and leaky SCID from California and other states were treated

222 py; these infants had typical SCID (n = 11), leaky SCID or Omenn syndrome (n = 3), or complete DiGeor

223 Most of the patients with leaky SCID were compound heterozygous for 1 loss-of-func

224 We have studied a mut/mut mouse model of leaky SCID with a homozygous Rag1 S723C mutation that im

225 rphic mutations can cause milder phenotypes (leaky SCID).

226 Screening detected 52 cases of typical SCID, leaky SCID, and Omenn syndrome, affecting 1 in 58,000 in

227 ng 68 patients with typical SCID and 32 with leaky SCID, Omenn syndrome, or reticular dysgenesis.

228 typical SCID; 13% were classified as having leaky SCID, Omenn syndrome, or reticular dysgenesis; and

229 1S723C/S723C mice, which serve as a model of leaky SCID, with agonists of the virus-recognizing recep

230 ional proteins and are often associated with leaky SCID.

231 restricted repertoire, reminiscent of human leaky SCID.

232 ctors, including the diagnosis of typical vs leaky SCID/Omenn syndrome, diagnosis via family history

233 The infant had "leaky" SCID (i.e., a form of SCID in which a minimal deg

234 A leaky self-incompatibility system was found, with self p

235 tial loss of T cells in a spectrum including leaky severe combined immunodeficiency (LS) and Omenn sy

236 cells to the pathology of Omenn syndrome and leaky severe combined immunodeficiency (SCID) has not be

237 binding of the inhibitor FKBP12 and promote leaky signaling in the absence of ligand.

238 FKBP12-mediated kinase inhibition to produce leaky signaling.

239 y mechanism in STKR1 to prevent pathological leaky signaling.

240 ith a higher risk of malignancy, compared to leaky splice site mutations.

241 Among all BRCA2 VUS, those causing partial/leaky splicing defects are the most challenging to class

242 ping to determine the pathogenicity of BRCA2 leaky splicing variants, some of which may not increase

243 ted by long-lived (~100 seconds) inactive or leaky states.

244 We develop a generalization of the leaky stochastic accumulator model using a Langevin equa

245 We used a leaky stochastic accumulator to model the neural decisio

246 more efficient than nonsynaptic (stationary, leaky) supply of glutamate in controlling sustained NMDA

247 hift sequences, as well as the Sindbis virus leaky termination signal.

248 Here we take advantage of the leaky tetracycline promoter system in the Tat-transgenic

249 on (brush) in Lotus japonicus resulting in a leaky tetrameric channel.

250 We generated a novel mutant mouse (Dclre1c(leaky)) that develops a LS phenotype.

251 ion, making the tight junction (TJ) barrier "leaky." This effect was mediated by changes in the prote

252 corporation of the permeability-associated, "leaky" tight junction protein claudin-2 at intercellular

253 rphological defects revealed swollen hyphae, leaky tips, intrahyphal growth, and double cell wall, su

254 ominant form of metabolism; this resulted in leaky TJs and mislocalization of actin and TJ proteins.

255 ion, and the alveolar epithelial barrier was leaky to (125)I-albumin tracer compared to wild type.

256 by E17.5 and the urothelial barrier becomes leaky to luminal fluid.

257 in response to temperature, while preventing leaky transcription in the absence of an activation sign

258 ing any mislocalized Oskar that results from leaky translational repression.

259 s for many currently untreated patients with leaky tricuspid valves.

260 tumor tissues by passing through abnormally leaky tumor blood vessels.

261 tters to tumor markers adjacent to a typical leaky tumor vascular system may have large antitumor eff

262 the ability of macromolecules to extravasate leaky tumor vessels and accumulate in the tumor tissue.

263 We found that in the presence of a leaky urothelium, intravesical K(+) sensitizes bladder a

264 Our study demonstrates that in the face of a leaky urothelium, urinary K(+) is the main determinant o

265 The leaky vaccine bias could account for some, but probably

266 ghlight that even partial vaccination with a leaky vaccine can have unforeseen positive consequences

267 ns to estimate the potential contribution of leaky vaccine effect to the observed decline in mVE.

268 in chickens to show that vaccination with a leaky vaccine substantially reduces viral load in both v

269 stering (early growth predicts the level of 'leaky' vaccine needed for control and peak time, while t

270 Analysis of a neutral leaky variant (c.231T>G) showed that a reduction of appr

271 of a role for TNP-470 in selection for less leaky vascular segments within healing wounds.

272 fect 0.1-0.5% of the population resulting in leaky vasculature and severe neurological defects.

273 We find that leaky vasculature can cause a net acidification of the n

274 at nanocarriers rely principally on abnormal leaky vasculature for tumor access, a transcytosis trans

275 nto circumventricular organs in the brain or leaky vasculature of late-stage intracranial tumors.

276 However, the leaky vasculature of tumors combined with a poor lymphat

277 mpaired in both models, even at sites with a leaky vasculature.

278 hments near hydrothermal vents, however, the leaky vent hypothesis argues that some hydrothermal Fe p

279 Formation of new immature and leaky vessels along with inflammatory remodeling of exis

280 hat PHD2 depletion prevents the formation of leaky vessels and edema by regulating endothelial barrie

281 as the potential to prevent the formation of leaky vessels and edema in inflammatory diseases such as

282 cross the endothelial barrier has to rely on leaky vessels arising from disease states such as pathol

283 atical modelling to examine the potential of leaky vessels as an additional source of stromal acidifi

284 ted endothelial sprout clumping in vitro and leaky vessels in vivo.

285 cd93 was observed in pancreatic islets, and leaky vessels were apparent in cd93-deficient pancreases

286 ascular permeability due to the presence of "leaky vessels".

287 idly growing tumors, transporting fluid from leaky vessels, and/or connecting with the constitutional

288 Using a leaky-wave antenna with a broadband transmitter, we demo

289 omising applications of these structures are leaky-wave antennas which utilize the low frequency depe

290 detailed understanding of the radiation from leaky-wave devices, offers a realistic approach for enab

291 g the array, which connects the patch to the leaky-wave open-ended feeding slot-lines running underne

292 The metal-clad leaky waveguide (MCLW) is an optical biosensor consistin

293 h range was enabled by the use of mesoporous leaky waveguides (LWs) made of chitosan.

294 e it is unknown whether influenza vaccine is leaky, we simulated the 2011-2012 to 2014-2015 influenza

295 The leaky well was located 170 m away from a monitoring well

296 when acidic, CO(2)-rich fluids flow along a leaky wellbore.

297 RPE from apoptosis, but makes the monolayer leaky when it is presented to the apical side of the mon

298 e failure in arterial maturation, and become leaky with the onset of coronary perfusion.

299 ired either by making the ryanodine receptor leaky (with caffeine or ryanodine) or by decreasing sarc

300 Protocell membranes that were initially leaky would eventually become less permeable, forcing ce