ライフサイエンスコーパス: lectin

1 by H84T, was only somewhat decreased by the lectin.

2 cans, which serve as a major ligand for this lectin.

3 PHA alleles affected the stability of PHA-L lectin.

4 by the Phaseolus Vulgaris erythroagglutinin lectin.

5 n a native cell surface using antibodies and lectins.

6 and sialic acid-binding immunoglobulin-like lectins.

7 kinetics and thermodynamics with immobilized lectins.

8 uirements for high affinity binding to these lectins.

9 h respect to binding by sialic acid-specific lectins.

10 formation of metastasis via association with lectins.

11 logically significant by pairing with tissue lectins.

12 on the binding mode between GNP-glycans and lectins.

13 to investigate the role of galactose-binding lectin 1 (Gal1) in immunotherapy resistance.

14 genes, including sialic acid-binding Ig-like lectin 1 (Siglec-1), a receptor on monocytes/macrophages

15 ibitory receptor sialic-acid-binding Ig-like lectin 10 (Siglec-10), which is expressed by tumour-asso

16 -discovered heparin-binding proteins, C-type lectin 14a (CLEC14A), a member of the C-type lectin fami

17 Sialic acid-binding immunoglubulinlike lectin 9 (Siglec-9) is a ligand of vascular adhesion pro

18 in, i.e. the human macrophage galactose-type lectin, a plant lectin, Pisum sativum agglutinin, and th

19 uction in the trypsin inhibitor (85.97%) and lectin activity (100%) was observed.

20 hift analysis did suggest that Bap1 exhibits lectin activity with a preference for anionic or linear

21 ylation sites, site-directed mutagenesis and lectin affinity purification identified N65 and N82 as b

22 ation of these tobacco plants expressing hvt-lectin against lepidopteran insects.

23 ensors, confirming that the use of different lectins allows to monitor different antigen expression.

24 SCR-2-3-4 inhibited both lectin and alternative pathway activation by nanoparticl

25 at hC3Nb2 is cross-reactive and inhibits the lectin and alternative pathway in murine serum.

26 charides recognized by the Galanthus Nivalis lectin and biantennary galactosylated N-glycans recogniz

27 SFV strains and strongly suggest that C-type lectin and CD2v may experience substantial selective pre

28 Although excessive activation of the lectin and classical pathways contributes to multiple au

29 KAP-deficient T cell disappearance, both the lectin and classical pathways were genetically ablated.

30 diated by expression of activation-dependent lectin and its T cell-binding partner, N-acetyl-D-glucos

31 in-Latrophilin complexes that reveal how the lectin and olfactomedin domains of Latrophilin bind acro

32 s ligands identifying CTRP6 as a novel human lectin and PRM of importance for complement recognition

33 nteraction is predicted to occur between the lectin and the branched side chains present on Psl.

34 es a two-domain protein containing predicted lectin and Toll/Interleukin-1 receptor domains.

35 binant human galectin-3 and five other known lectins and also tested CaRe's ability to purify glycopr

36 Although lectins and anti-ganglioside antibodies did not differen

37 Besides purifying lectins and glycoproteins, CaRe has the potential to pur

38 have been instrumental in isolating numerous lectins and glycoproteins.

39 ina cristagalli lectin (ECL), Sambucus nigra lectin, and Phaseolus vulgaris Erythroagglutinin (PHA-E)

40 sponses, with emphasis on the role of C-type lectins, and discuss how these receptors modulate these

41 ctor receptors, integrins, integrin ligands, lectins, and other type-1 transmembrane proteins.

42 SP2 [thrombospondin-2], MBL [mannose-binding lectin]; and 3 with lower risk: ErbB1 [epidermal growth

43 croarray to examine binding specificities of lectins, anti-ganglioside antibodies, and serum antibodi

44 n-binding scaffolds that include antibodies, lectins, aptamers and boronic acid-based entities.

45 The lectins are captured in the solution phase by multivalen

46 Glycan-binding proteins such as lectins are ubiquitous proteins that mediate many biolog

47 ement of C-type lectins, here we developed a lectin array and suitable protocols for labeling of micr

48 Our findings indicate that mammalian lectin arrays represent unique discovery tools for ident

49 ochemical, and functional analysis implicate lectins as FAMK-1 substrates.

50 Enzyme-linked lectin assay was used to screen PS-SGCL against two plan

51 Secretion was measured by an enzyme-linked lectin assay, change in intracellular [Ca(2+)] ([Ca(2+)]

52 collectin-10, collectin-11, mannose-binding lectin-associated serine protease-1, and mannose-binding

53 iated serine protease-1, and mannose-binding lectin-associated serine protease-2.

54 Mannan-binding lectin-associated serine proteinase 2 (MASP-2) is essent

55 in conjunction with the results from the ECL lectin authenticates the composition of the agalactosyla

56 are offered to inspire the consideration of lectin-based approaches to thwart infection by present a

57 effect of rectal application of an anti-HIV lectin-based microbicide Q-Griffithsin (Q-GRFT) in recta

58 Sperm lectins bind to oviductal glycans to form the reservoir.

59 They can not only quantify the GNP-glycan-lectin binding affinities via a new fluorescence quenchi

60 a platform to systematically elucidate MUC1-lectin binding specificities, which in the long term may

61 was performed by laser Doppler flowmetry and lectin-binding assay.

62 To address this, we developed a novel lectin-binding panel to enable human VWF glycan characte

63 ing against P. aeruginosa infection, through lectin blocking and the near-infrared-light-induced phot

64 c receptors, was evaluated by Sambucus nigra lectin blotting.

65 o wild-type immature thymocytes required the lectin but not the classical pathway.

66 CaRe purifies lectins by utilizing their ability to form spontaneous n

67 t activation products covering the classical/lectin (C4d), alternative (C3bBbP) and common pathway (C

68 Natural-product derived lectins can function as potent viral inhibitors with min

69 The KS contact region involves the lectin canonical binding site, with estimated K(D) value

70 the medullary sinus (MS) expressed a C-type lectin CD209.

71 These two quality control sensors control lectin chaperone binding and glycoprotein egress from th

72 hage galactose-type lectin (MGL) is a C-type lectin characterized by a unique specificity for termina

73 C-type lectin CLEC16A is located next to CIITA, the master tran

74 bacteria as well as PRMs and enzymes of the lectin complement pathway.

75 nition molecules (PRMs) of the classical and lectin complement pathways.

76 The lectin content was analyzed using a haemagglutination as

77 s significantly decreased and TIA as well as lectins content had a reduction higher than 90%.

78 tol phosphates (IPs), trypsin inhibitors and lectins content.

79 Changes in noroVLP and lectin coverage, caused by competition, were monitored f

80 The C-type lectins CTL4 and CTLMA2 cooperatively influence Plasmodi

81 nisms between two closely related tetrameric lectins, DC-SIGN (simultaneous binding to one GNP) and D

82 acilitated infection of cells expressing the lectins dendritic cell-specific intercellular adhesion m

83 sduction system whereby cytoplasmic sentinel lectins detect membrane damage leading to ubiquitination

84 The P2K2 extracellular lectin domain binds to ATP with higher affinity than P2K

85 lustrate how changes within the noncatalytic lectin domain can alter the recognition of both peptide

86 catalytic domain and a C-terminal ricin-like lectin domain comprised of three potential GalNAc recogn

87 ophages based on surface marker CD301/C-type lectin domain family 10 member A expression.

88 strated a novel role for the alpha repeat of lectin domain in influencing charged peptide preferences

89 We found that the C-type lectin domain of CLEC14A binds one-to-one to heparin wit

90 The structure reveals that the N-terminal lectin domain of LPHN3 binds to the TEN2 barrel at a sit

91 suggest that small peptides derived from the lectin domain of SP-A2 that contain the major allelic va

92 In BCoV, an HE lectin domain promotes esterase activity toward clustere

93 d catalyzing transfer of GalNAc, whereas the lectin domain recognizes more distant extant GalNAc on p

94 ino acid substitution at position 223 of the lectin domain, was shown to alter the ability of SP-A to

95 Here, we report that layilin, a C-type lectin domain-containing membrane glycoprotein, is selec

96 h unique interactions with its catalytic and lectin domains, the molecular basis for this distinct su

97 ly engendered via binding of the endothelial lectin E-selectin (CD62E) to its cognate ligand, sialyl

98 euria aurantia lectin, Erythrina cristagalli lectin (ECL), Sambucus nigra lectin, and Phaseolus vulga

99 ctive with both TL and Erythrina cristagalli lectin (ECL, terminal LacNAc), indicating synthesis of p

100 nalyzed ASFV serotype-specific locus (C-type lectin (EP153R) and CD2v (EP402R)) in order to allocate

101 Aleuria aurantia lectin, Erythrina cristagalli lectin (ECL), Sambucus nig

102 e is a time-saving procedure that can purify lectins even from a few milliliters of crude protein ext

103 ways after engagement with calcium-dependent lectins expressed by tissue macrophages.

104 R), suggesting that inefficient infection of lectin-expressing leukocytes could contribute to the att

105 facilitating attachment to and infection of lectin-expressing leukocytes.

106 Many members of the C-type lectin family of glycan-binding receptors have been ascr

107 lectin 14a (CLEC14A), a member of the C-type lectin family that modulates angiogenesis.

108 ay of complement activation: mannose-binding lectin, ficolin-2, ficolin-3, collectin-10, collectin-11

109 specifically target a particular multimeric lectin for therapeutic interventions, especially under t

110 f the cancer-associated T antigen, using the lectin from Arachis hypogaea (peanut agglutinin, PNA) as

111 The array contains C-type lectins from cow, chosen as a model organism of agricult

112 owing the competition between noroVLPs and a lectin (from Ralstonia solanacearum) upon binding to the

113 aying OC43 evolution, we knocked out BCoV HE lectin function and performed forced evolution-populatio

114 OC43 and HKU1, however, lost HE lectin function as an adaptation to humans.

115 coproteins, a change that is detected by the lectin Galanthus nivalis agglutinin (GNA).

116 We present the detection of the soybean lectin gene as a species control, and P35S as a transgen

117 t the coding sequence of a S. rosetta C-type lectin gene, rosetteless, and thereby demonstrate its ne

118 Lectin glycan preferences are usually centered on specif

119 Multivalent lectin-glycan interactions are widespread in biology and

120 powerful mechanistic probes for multivalent lectin-glycan interactions.

121 was used to screen PS-SGCL against two plant lectins, Glycine max soybean agglutinin and Vicia villos

122 The antiviral lectin, Griffithsin (GRFT), has been shown to be both sa

123 previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against

124 We previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spect

125 -glycero-alpha-d-manno-heptose) suggests the lectin has evolved to recognize distinct bacterial speci

126 nding proteins, particularly mannose-binding lectins, have also been shown to bind these glycans.

127 microbes and the large complement of C-type lectins, here we developed a lectin array and suitable p

128 We used established lectin histochemistry to show that PNNs undergo drastic

129 graphy (UPLC), weak anion exchange-UPLC, and lectin histochemistry.

130 rminal region of SNX3 recruits galectin-9, a lectin implicated in protein and membrane recycling, whi

131 lity of microglia stained with a fluorescent lectin in tissue slices from female and male epileptic p

132 d a double gene construct expressing Hvt and lectin in tobacco (Nicotiana tabacum) plants under phloe

133 function relationships, researchers must use lectins in their purest form.

134 K-1 phosphorylation of substrates, including lectins, in the late secretory pathway is important in e

135 t tumor vessels that were more functional as lectin injection revealed more perfusion, and functional

136 Targeting the inferred mannose-lectin interaction holds therapeutic promise.

137 strengthening mechanism for the carbohydrate-lectin interaction that occurs when bacteria initially i

138 Multivalent carbohydrate-lectin interactions at host-pathogen interfaces play a c

139 rational design for novel inhibitors of MUC1-lectin interactions involved in tumor spread and glycope

140 r glycoside effect" observed in carbohydrate-lectin interactions.

141 aneously block all binding sites of a target lectin is key to robust inhibition of viral infection.

142 that galectin-8, a beta-galactoside-binding lectin, is upregulated in the epidermis of human psoriat

143 sistance included those carrying domains for lectin kinase, R gene, aspartyl protease, etc.

144 Pre-metamorphic tadpoles have abundant lectin-labeled pericellular material, which we interpret

145 P. aeruginosa produces lectins LecA and LecB, which possess affinities towards

146 Two extracellular P. aeruginosa lectins, LecA and LecB, are essential structural compone

147 dic inhibitors of the Pseudomonas aeruginosa lectin LecB with antibiofilm activity.

148 tions are frequently based on the binding of lectin-like adhesins to specific glycan determinants exp

149 We also show that the second C-type lectin-like domain (CTLD2) is critical for the uptake of

150 cytes and other cells, contains a C-terminal lectin-like domain that resembles C-type carbohydrate-re

151 nts, and glycan array analysis employing the lectin-like domains of cow and mouse CD23 demonstrate th

152 comprising two intercalated rings of C-type lectin-like domains, where the N-terminal cysteine-rich

153 ivity of the multi-ligand scavenger receptor Lectin-like Oxidized LDL Receptor-1 (LOX-1) is associate

154 ptosis in cultured endothelial cells through lectin-like oxidized LDL receptor-1 (LOX-1) signaling, a

155 m are a platelet activation receptor, C-type lectin-like receptor 2 (CLEC-2), and its endogenous liga

156 example, increased expression of killer cell lectin-like receptor B1 (KLRB1; CD161) 28 days postvacci

157 Further, we examined killer cell lectin-like receptor G1 (KLRG1) as a marker of this popu

158 CD8+ T cells expressing CD57 and killer cell lectin-like receptor G1 (KLRG1), which was negatively as

159 The activation of platelet receptor C-type lectin-like receptor II-type (CLEC-2) could partially me

160 discovered platelet receptor CLEC-2 (C-type lectin-like receptor) perpetuates and worsens liver dama

161 Previously we showed that the L-type lectin, LMAN2, limits trans-Golgi Network (TGN)-to-endos

162 Cdh6(high), lotus tetragonolobus lectin-low (LTL(low)) cells serve as PT progenitors and

163 calyx stained by the PNA (peanut agglutinin) lectin marker.

164 ome key lectins remain unknown and different lectins may exhibit overlapping glycan specificity.

165 The collectins mannose-binding lectin (MBL) and surfactant protein D (SP-D) are regulat

166 Collectins such as mannose-binding lectin (MBL) and surfactant protein D (SP-D) become temp

167 dy, we provide evidence that mannose-binding lectin (MBL) binds to beta2-GPI in Ca(++) and a dose-dep

168 ydrate recognition domain of mannose binding lectin (MBL) to target native HIV Env (CD4-MBL CAR).

169 tor D and Bb, lectin pathway mannose-binding lectin (MBL), and shared neurotoxic effectors C3b and C5

170 discovered that ligation of mannose-binding lectin (MBL), which binds to glycans of the fungal wall

171 s the serum concentration of mannose-binding lectin (MBL), which exacerbates local inflammatory proce

172 al centers in a complement-, mannose-binding lectin (MBL)-, and immunogen glycan-dependent manner.

173 hat inhibits the function of Mannose Binding Lectin (MBL).

174 binds and inactivates C1 and mannose-binding lectin (MBL)/ficolins, important pattern- recognition re

175 Also, the mannan-binding lectin (MBL2), an innate immune lectin that negatively i

176 Various recombinant mannose binding lectins (MBLs) and MBLs in sera of both murine and human

177 Dendritic cell (DC) lectins mediate the recognition, uptake, and processing

178 distinct glycans is central to biology, and lectins mediate this function.

179 The human macrophage galactose-type lectin (MGL) is a C-type lectin characterized by a uniqu

180 Macrophage galactose lectin (MGL) together with AMR mediated clearance of des

181 nd their receptor, macrophage galactose-type lectin (MGL), on CD163(+) TAMs in glioblastoma patient-d

182 ) interferes with IgE activity, we performed lectin microarray analysis to unravel the relationship b

183 isease severity using a ferret model and our lectin microarray technology.

184 c osteocytes via macrophage-inducible C-type lectin (Mincle), which induced their differentiation and

185 MP@silica@Au with affinity bound PSA to the lectin modified electrode surface.

186 In this study, we report one such lectin named horcolin (Hordeum vulgare lectin), seen to

187 to delineate the multivalency effects of the lectin-nanostructure interactions.

188 L. tomentosa contained no lectins or protease inhibitors (chymotrysin and trypsin)

189 lassical (CP), the alternative (AP), and the lectin pathway (LP) based on the recognized molecules.

190 The lectin pathway (LP) of the complement system is an impor

191 ctivated via the classical pathway (CP), the lectin pathway (LP), or the alternative pathway (AP), an

192 C3 proconvertase and inhibits classical and lectin pathway activation upstream of C3 activation.

193 ially) protected by the Ixodes Tick Salivary Lectin Pathway Inhibitor (TSLPI) protein; a salivary gla

194 Ficolin-3, the most abundant lectin pathway initiator in humans, circulates as disulf

195 the glomeruli and tubules indicated that the lectin pathway likely contributed to complement activati

196 ay C4b, alternative pathway factor D and Bb, lectin pathway mannose-binding lectin (MBL), and shared

197 s (IGFBPs)" route in allergic asthma and the lectin pathway of complement activation in nonallergic a

198 s, among other substrates, components of the lectin pathway of complement activation: mannose-binding

199 Activation of the classical and lectin pathway of complement may contribute to tissue da

200 common pathway (C3bc, C5a, and sC5b-9), the lectin pathway recognition molecule MBL, and antibody se

201 and activates the complement system via the lectin pathway.

202 contribute to complement activation via the lectin pathway.

203 directly with the activating enzymes of the lectin pathway; however, we could show the specific recr

204 ment C3 deposition through the classical and lectin pathways in human serum and in mouse serum.

205 cks the first step in both the classical and lectin pathways of complement activation and also inhibi

206 high-affinity inhibitor of the classical and lectin pathways of the complement cascade under both in

207 The classical and lectin pathways of the complement system are important f

208 positioned to target both the classical and lectin pathways while leaving the alternative pathway in

209 ts, presumably due to increased stability of lectin phytohemagglutinin L (PHA-L) compared to the wild

210 an macrophage galactose-type lectin, a plant lectin, Pisum sativum agglutinin, and the bacterial Gal-

211 lations) and glycosylation-binding proteins (lectins) play key roles in evading the immune system to

212 Additionally, high-mannose-binding lectins possess a broad capacity to neutralize and preve

213 d MON89788 soybean genomic DNA with P35S and lectin primer sets.

214 Conjugation of ciprofloxacin to lectin probes enabled biofilm accumulation in vitro, red

215 Galectin-9, a beta-galactoside-binding lectin, promotes immune suppression through T-cell inhib

216 We found that mannose binding lectins, proteins naturally present in the serum of mice

217 Lastly, we found Dectin-1, a c-type lectin PRR to be reduced at the protein level in both na

218 labeling, peptide-N-glycosidase F treatment, lectin pulldowns, and exoglycosidase treatment, we have

219 w that a toll-like receptor (TLR) and C-type lectin receptor (CLR) agonist pairing of monophosphoryl

220 loglycoprotein receptor (DC-ASGPR), a C-type lectin receptor (CLR) expressed on human DCs, resulted i

221 Whether the PRRs of the C-type lectin receptor (CLR) family including Dectin-2 may be i

222 replication significantly upregulated C-type lectin receptor (CLR) macrophage-inducible Ca2+-dependen

223 or (CLR) macrophage-inducible Ca2+-dependent lectin receptor (Mincle).

224 receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immu

225 onsisting of a Toll-like receptor and C-type lectin receptor agonist pairing that significantly incre

226 We demonstrate that the lectin receptor kinase (LecRK), LecRK-VI.2, is a potenti

227 We demonstrate that the lectin receptor kinase RDA2 is essential for perceiving

228 bidopsis (Arabidopsis thaliana) P2K1 (L-type lectin receptor kinase-I.9), was shown to contribute to

229 mapped and is defective in a gene encoding a lectin receptor kinase.

230 Their exclusive expression of the C-type lectin receptor Langerin makes them prominent candidates

231 halose-6,6-dimycolate (TDM) binds the C-type lectin receptor MINCLE and induces inflammatory gene exp

232 The Syk-coupled C-type lectin receptor Mincle detected mucosal-resident commens

233 Mincle is a C-type lectin receptor of the innate immune system with the abi

234 The C-type lectin receptor pathway activates both MAPK and NF-kappa

235 show that recruited IDCs express the C-type lectin receptor SIGN-R1, which mediates direct recogniti

236 IL-17 signaling, Chemokine signaling, C-type lectin receptor signaling and Toll-like receptor signali

237 s a myeloid cell-expressed inhibitory C-type lectin receptor that can sense cell death under sterile

238 nized by Mincle (macrophage inducible C-type lectin receptor), and its adjuvanticity depends on the i

239 occur in mice lacking alpha-granules, C type lectin receptor-2 (CLEC-2), or protease activated recept

240 e marrow-derived dendritic cells from C-type lectin receptor-deficient mice revealed that the immunos

241 in and mRNA levels, thereby affecting C-type lectin receptor-induced modulation of IDO activity in DC

242 The C-type lectin receptor-Syk (spleen tyrosine kinase) adaptor CAR

243 hat are associated with activation of C-type lectin receptors (CLR) Dectin-1- and Dectin-2-mediated C

244 significant mRNA upregulation of both C-type lectin receptors (CLR) Mincle and MCL in Msg protein pre

245 The C-type lectin receptors (CLR) MINCLE, MCL, and DECTIN-2 are exp

246 Herein we demonstrate that 2 C-type lectin receptors (CLRs) Mcl and Mincle play an important

247 C-type lectin receptors (CLRs) play key roles in antifungal def

248 degradation, as virus engagement with C-type lectin receptors (CLRs), such as DC-SIGN (DC-specific IC

249 pattern recognition receptors such as C-type lectin receptors (CLRs).

250 us TLRs (TLR2, TLR3, TLR4, and TLR7), C-type lectin receptors (Dectin-1, Dectin-2, and Mincle), and t

251 ng and activating dendritic cells via C-type lectin receptors and reduce side effects.

252 patterns impact their recognition by C-type lectin receptors and the immunomodulatory effect of the

253 ation of both Toll-like receptors and C-type lectin receptors is required for IRF1-mediated IRGB10 re

254 Surprisingly, activity at the C-type lectin receptors was particularly powerful, with C5aR2 a

255 In a targeted screen of C-type lectin receptors, a Clec2d reporter responded to lysates

256 of FcgammaRII, type II Fc receptors, C-type lectin receptors, and sialic acid-binding immunoglobulin

257 s mediated through the recognition of C-type lectin receptors, mainly elicited by structurally unique

258 s on the expression levels of two key C-type lectin receptors, namely the mannose receptor and DC-spe

259 molecules but prominent expression of C-type lectin receptors.

260 ce after sample incubation was indicative of lectin recognition and complex formation between PNA and

261 Glycan-lectin recognition is assumed to elicit its broad range

262 Glycan-lectin recognition is vital to processes that impact hum

263 IRS-like conditions), we employed the C-type lectin-related protein rhodocetin-alphabeta (RCalphabeta

264 However, the structural details of some key lectins remain unknown and different lectins may exhibit

265 o specifically block bacterial LecA and LecB lectins, respectively, which are essential for bacterial

266 tive targeting of glycans on CD11b with such lectins results in altered intracellular signaling event

267 amer to identify the unfurling of the second lectin ring which enables tetramer formation.

268 not reveal key structural information, e.g., lectin's binding site orientation, binding mode, and int

269 such lectin named horcolin (Hordeum vulgare lectin), seen to lack mitogenicity owing to the divergen

270 Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 is selectively expressed on eosinophil

271 Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is expressed on mast cells and eosinop

272 Sialic acid-binding immunoglobulin-like lectins (Siglec)-like domains of streptococcal serine-ri

273 Sialic acid-binding Ig-type lectins (Siglecs) are cell surface receptors found on im

274 Sialic acid-binding immunoglobulin-type lectins (Siglecs) are expressed on the majority of white

275 ids, sialic acid-binding immunoglobulin-like lectins (Siglecs) play a pivotal role in regulating many

276 nd inhibitory Sia-recognizing Ig superfamily lectins (Siglecs) to block neutrophil and macrophage act

277 in myeloid cells that is involved in C-type lectin signaling and antifungal immunity.

278 cell marker), YFP (lineage marker), and GSII lectin (spasmolytic polypeptide-expressing metaplasia ma

279 When the lectin specificity matches the N-glycan, the peak disapp

280 g) domains, D00-D2, extending into the fifth lectin subdomain (D3) that binds to the Tir-receptor on

281 k defines the starting point for new biofilm/lectin-targeted drugs to modulate antibiotic properties

282 Increasingly, the B-galactoside binding lectins, termed galectins, are being recognized as criti

283 tln-1, also known as Omentin-1) is a soluble lectin that binds a range of microbial sugars, including

284 om human retina are recognized by jacalin, a lectin that binds to O-glycans, preferentially to Gal-Ga

285 RFT) is high-mannose oligosaccharide binding lectin that has shown in vivo broad-spectrum activity ag

286 Galectin-3 is a beta-galactoside-binding lectin that is highly expressed within the tumor microen

287 nnan-binding lectin (MBL2), an innate immune lectin that negatively impacts influenza outcomes, recog

288 MBL is a C-type lectin that recognizes oligosaccharides on pathogens and

289 Specifically, the mannose-binding lectins that best agglutinate glycodendrimersomes are th

290 C-type lectins that contain collagen-like domains are known as

291 TfR binds tomato lectin (TL), specific for N-acetyllactosamine (LacNAc) r

292 tegrates a unique combination of enzymes and lectins to modify sialylated N-glycans in real time in t

293 eruginosa uses adhesins (e.g., LecA and LecB lectins, type VI pili and flagella) and iron to invade h

294 reductions in a subset of zona pellucida and lectin-type proteins between wild-type and mutant chorio

295 (Gal3), a beta-galactoside-binding cytosolic lectin, unifies and coordinates ESCRT and autophagy resp

296 tion calorimetry experiments reveal that the lectin was sensitive to the length and branching of mann

297 ctivation of polysaccharide and glycoprotein lectin, which are important properties for latex product

298 5 is a conserved sialic acid-binding Ig-like lectin, which is expressed on osteoclasts.

299 minimizes the mitogenicity of the wild-type lectin while maintaining antiinfluenza activity in vitro

300 Epa family members are lectins with binding pockets containing several conserve