ライフサイエンスコーパス: left-handed

1 age, 65 [54-81] years; 3 of 9 male [33%]; 0 left-handed).

2 double helix around microtubules, which are left-handed.

3 reclassified into 2 groups: right-handed and left-handed.

4 They were less likely to smoke or to be left-handed.

5 on these peptides in chloroform indicated a left-handed 10/12-helix, while the CD spectrum in methan

6 mixture of polyproline II (PPII) and a novel left-handed 2.5(1)-helical conformation, which is an ext

7 74 [67-76] years; 1 of 5 male [20%]; 1 of 5 left-handed [20%]; and nfvPPA-CBD group: mean [IQR] age,

8 b predominantly sampled the right-handed and left-handed 3(10)-helix region and to a minor extent the

9 ity inversion of poly(BBPFA) proceeds from a left-handed 31 helix via multistate free energy pathways

10 ation is predicted to be almost a contracted left-handed 4-fold helix; i.e. similar to that observed

11 s (8 women and 17 men; 23 right-handed and 2 left-handed; age range, 16-64 years), who did language,

12 cal forms, right-handed all-cis (Form I) and left-handed all-trans (Form II), were determined in the

13 c carboxy termini are uniquely arranged in a left-handed alpha-helical bundle, directly interacting w

14 s for interacting with a molecular target, a left-handed alpha-helix.

15 to adopt compact right-handed (alpha(R)) and left-handed (alpha(L)) helical conformations.

16 some achiral and chiral substituents such as left-handed amino acids have been used.

17 iological molecules (right-handed sugars and left-handed amino acids) is a signature of life.

18 Strikingly, the twisting is always left-handed and is not due to underlying cytoskeletal sk

19 a cubane iron-sulfur cluster indicates both left-handed and right-handed folds could exist and have

20 i is by the propagation of kinks, separating left-handed and right-handed helical waves.

21 cus depth is significantly different between left-handed and right-handed individuals as determined b

22 pendent effective chemical potentials of the left-handed and right-handed Weyl points.

23 are antiparallel, the global architecture is left-handed and the two component DNA strands are orient

24 ree broad categories namely "right-handed", "left-handed", and "M-shape".

25 patients were right handed, nine (15%) were left handed, and six (10%) had indeterminate hand domina

26 ctions in the DNA origami structures adopt a left-handed antiparallel conformation.

27 trast, soluble beta-helices, both right- and left-handed, are usually "capped" on each end by one or

28 Both right- and left-handed batters performed better in years dominated

29 emonstrate that this metamaterial exhibits a left-handed behaviour, and we directly observe the Chere

30 d a shared second domain predicted to form a left-handed beta helix are all critical for interprotein

31 extensive interactions between the PLDs and left-handed beta helix domains that form the eIF2Bgammae

32 ver, poor sequence homology between PglD and left-handed beta helix enzymes with existing structural

33 analysis predicts PglD to be a member of the left-handed beta helix family of enzymes.

34 equence of PrP is compatible with a parallel left-handed beta-helical fold.

35 Our parallel left-handed beta-helical model provides a coherent frame

36 imeric or hexameric arrangement of right- or left-handed beta-helical models.

37 Left-handed beta-helices readily form trimers, providing

38 nstruct nanotubes using building blocks from left-handed beta-helices which are commonly occurring re

39 The left-handed beta-helix (LHBH) is an intriguing, rare str

40 This revealed an unusual left-handed beta-helix domain, with the phosphorylation

41 cterial acetyltransferase is a member of the left-handed beta-helix family and forms a homotrimer as

42 nit of the trimeric enzyme is dominated by a left-handed beta-helix motif with 11 turns.

43 erB, an N-acetyltransferase belonging to the left-handed beta-helix superfamily of proteins.

44 The C-terminal domain consists of a left-handed beta-helix, which has nearly seven turns.

45 beta-strands, 23 of which form the canonical left-handed beta-helix.

46 t these fibrils are composed of conventional left-handed beta-sheets, but that packing stresses betwe

47 l enantiomeric excess (EE) between right and left-handed biomolecules.

48 phenotype in POMT mutant embryos that shows left-handed body torsion.

49 The enzyme relaxes positive supercoils and left-handed braids 20 times faster, and with greater pro

50 Electrostatic stabilization of left-handed braids may stand behind the chiral selectivi

51 of the Prickle protein determines right- or left-handed bristle morphogenesis.

52 The filaments formed with ATP are left-handed, but surprisingly these filaments exert no t

53 entric metal-rings essentially act as series left-handed capacitances C(L) that extend the effective

54 propyzamide, which normally causes enhanced left-handed CFR and right skewing.

55 Twenty-seven left-handed children (17 boys, 10 girls) and 54 age- and

56 dence of atypical language lateralization in left-handed children in this study was similar to that r

57 values for the temporo-parietal ROI for the left-handed children were 18 (67%) left-dominant, 6 (22%

58 and splenium) and for overall CC size, with left-handed chimpanzees exhibiting significantly smaller

59 In particular, for a left-handed chiral tip, transverse forces are attractive

60 Electron tomography revealed a left-handed chirality in the spiral tubes, double-wall t

61 Here, we demonstrate that left-handed chirality of the MreB cytoskeleton in the ro

62 Some of these tubes spontaneously form with left-handed chirality.

63 and TM (transverse magnetic) as well as LCP (left-handed circular polarization) and RCP (right-handed

64 dispersions of racemic CdTe NPs with right- (left-)handed circularly polarized light (CPL) induces th

65 by the superposition of deflected right- and left-handed circularly polarized component vortices with

66 were examined by five right-handed and five left-handed clinicians.

67 ed by L-enantiomers of Asp and Glu, whereas 'left-handed' (clockwise) morphology is induced by D-enan

68 tral standing dimer and form both right- and left-handed clusters on a conducting substrate.

69 e NMR structure of the zetazeta(TM) dimer, a left-handed coiled coil with substantial polar contacts.

70 y that these proteins can adopt conventional left-handed coiled coils.

71 with the transmembrane domains arranged in a left-handed coiled-coil configuration, crossing the bila

72 . coli subunit b-dimer can stably exist as a left-handed coiled-coil.

73 ide chains, like those found in conventional left-handed coiled-coils, and this packing governs the c

74 tructural models, including right-handed and left-handed coiled-coils.

75 t the proteins all are capable of packing as left-handed coiled-coils.

76 E. coli ATP synthase could pack into stable left-handed coiled-coils.

77 enantiopure CTVs and mixtures of right- and left-handed columns from racemic by mixture, racemic by

78 encies and pave the way towards magnetic and left-handed components for visible optics.

79 We demonstrate that the bound DNA is in the left-handed conformation and identify key interactions f

80 ference of H3/H4 to form negative coils (the left-handed conformation).

81 the N-terminus preferentially stabilized the left-handed conformer (DNA negatively supercoiled), and

82 These domains recognize the left-handed conformer of dsDNA and dsRNA known as Z-DNA/

83 d a mixed effect, i.e., when at serines, the left-handed conformer, and at threonines, a mixture of b

84 Variant H3.3 promoted only the left-handed conformer, and H3.1 tended to maintain both

85 ree molecular entities: the right-handed and left-handed conformers and a nonhelical domain.

86 tructure features such as split beta-sheets, left-handed connections, and crossing loops.

87 t-handed circularly polarized (CP) light and left-handed CP luminescence based on PBG.

88 were distorted relative to the WT and showed left-handed crossing of their helices.

89 due to its geometrical preference to act on left-handed crossings, Topo IV can specifically unknot s

90 freshly replicated sister DNA molecules form left-handed crossings.

91 ransition from a parallel TM helix pair to a left-handed crossover arrangement.

92 ed by the topological challenge of forming a left-handed crossover connection between beta-strands S2

93 central beta-sheet and alpha-helix C in the left-handed crossover connection between beta-strands tw

94 crossovers by groove-backbone interaction or left-handed crossovers by groove-groove juxtaposition.

95 Surprisingly, left-handed crossovers, assembled by sequence-independen

96 otably, molecular dynamics revealed that the left-handed dimer gets tilted en bloc, whereas conformat

97 for subunit b can be accommodated by classic left-handed, dimeric coiled-coil quaternary structures.

98 tablished heptad-repeat packing exhibited by left-handed, dimeric coiled-coils by employing simulated

99 d DNA helix is translocated and rotated in a left-handed direction.

100 ting subunits, and 2- to 5-fold enhanced for left-handed distal subunits.

101 Interest to the left-handed DNA conformation has been recently boosted b

102 R solution and X-ray crystal structures of a left-handed DNA G-quadruplex.

103 The left-handed DNA structure, Z-DNA, is believed to play im

104 equences capable of forming either right- or left-handed DNA under physiological conditions, forming

105 nucleosomes are octameric with conventional left-handed DNA wrapping, in contrast to other recent pr

106 dard histone H3-containing nucleosome with a left-handed DNA writhe at a nonfunctional STB.

107 [Co(NH(3))(6)](3+), (dm(5)C-dG)(4) assumes a left-handed double helical structure (Z-DNA), whereas th

108 stable, existing as a mixture of right- and left-handed double helices, which eventually undergo an

109 C-I...S halogen bonds that lead to right- or left-handed double helix when the two alanine residues a

110 NA and Z-RNA, nucleic acid structures with a left-handed double helix, is poorly understood(1-3).

111 olves formation of a bipolar spindle made of left-handed double-helical actin-like ParM filaments.

112 have high potential to form the nonclassical left-handed double-helical Z-DNA structure.

113 step, a clear preference of R-BINAS for the left-handed enantiomer of Au(38)(2-PET)(24) is observed

114 In the left-handed epilepsy population, there was high posttest

115 icantly different mean PD between right- and left-handed examiners (unadjusted P<0.05; differences at

116 in the measurement of PDs between right- and left-handed examiners at various locations in the mouth

117 easurements were compared between right- and left-handed examiners using analysis of variance (ANOVA)

118 record slightly higher PD measurements than left-handed examiners, but this difference did not reach

119 We replicated previous results showing that left-handed fighters are strongly overrepresented in pro

120 presented in professional combat sports, but left-handed fighters did not show greater variance in fi

121 thesis to date, finding robust evidence that left-handed fighters have greater fighting success.

122 Here, we report an unusually wide left-handed filament structure for an archaeal MCM, as d

123 four-helix bundle, and a pentameric parallel left-handed five-helix bundle.

124 Both right- and left-handed forms crystallized in the trigonal space gro

125 s the comparison with the rare but important left-handed forms.

126 ix 3 (PAH3) domain in the complex adopts the left-handed four-helix bundle structure characteristic o

127 residues of Zuo1 fold into an autoinhibitory left-handed four-helix bundle.

128 c modeling computations provide support to a left-handed geometry of double-stranded (S)-ZNA.

129 the disease-related human lysozyme, can form left-handed giant ribbons, closing into nanotubes.

130 These results also suggest that a left-handed Gly heptad repeat motif can drive membrane h

131 Left-handed gold nanoparticle double helices were prepar

132 nd simultaneously direct their assembly into left-handed gold nanoparticle double helices.

133 Based on the frontal ROI, in the left-handed group, 23 participants (85%) demonstrated le

134 rhm1 mutant roots also display left-handed growth.

135 lidated closed alpha-solenoid repeats with a left-handed helical architecture that--to our knowledge-

136 Although the left-handed helical conformation is not favorable for th

137 selectivity filter, Gly-77 in KcsA, is in a left-handed helical conformation.

138 d-state NMR and found that it forms a stable left-handed helical dimer.

139 in neutron star crusts, where the right- and left-handed helical elements differ only in their handed

140 eal that R-6-AO molecules self-assemble into left-handed helical fibers with cross-sectional diameter

141 opic studies showed that ICP8 will form long left-handed helical filaments.

142 as right and noncoronary fusion gave rise to left-handed helical flow with left-posterior flow jets (

143 HAMNOSE BIOSYNTHESIS 1 (RHM1) cause dramatic left-handed helical growth of petal epidermal cells, lea

144 ted by an array of pitch-balanced right- and left-handed helical membrane surfaces of different radii

145 step along the microtubule lattice, creating left-handed helical membrane tubes when pulling on giant

146 structural elements are consistent with two left-handed helical models: 2 residues/turn (2(4) helix)

147 tice and switch protofilaments, leading to a left-handed helical motion.

148 n (DD) complex, which surprisingly reveals a left-handed helical oligomer that consists of 6 MyD88, 4

149 membrane-soluble peptides with a Gly-based, left-handed helical packing motif would associate.

150 ional units is found to form both right- and left-handed helical structures.

151 e resulting family of structures exhibited a left-handed helical twist, in agreement with the twisted

152 s of polyproline II, beta-strand, right- and left-handed helical, and gamma-turn-like conformations.

153 s than are currently recognized in right- or left-handed helices, spirals, and in antidistorted struc

154 e show that each virion contains two nested, left-handed helices: an outer helix of matrix protein M

155 configurations of which are denoted Lambda (left handed helix) or Delta (right handed helix).

156 in, harbors nucleic acid-binding domains for left-handed helix (Z-form) and receptor-interacting prot

157 de containing both adenine and thymine, is a left-handed helix formed through Watson-Crick pairing be

158 de, amylose crystallizes as a regular single left-handed helix from a propanol, butanol, or iodine so

159 ight-handed helix in the subendocardium to a left-handed helix in the subepicardium.

160 rboxylate positions along the reported G2(+) left-handed helix of alpha-(2,8)-polysialic acid.

161 The NC within the virion forms a left-handed helix with an inner nucleoprotein layer deco

162 in omega2 binds to parS DNA, forming a short left-handed helix wrapped around the full parS, and inte

163 The axes are coiled around each other as a left-handed helix, and AFD1 showed a bilaterally symmetr

164 corresponding oligo adopts a right-handed or left-handed helix, or a nonhelical motif.

165 ce suggested that polycytidylic acid forms a left-handed helix.

166 n which flagellin monomers are arranged in a left-handed helix.

167 odel were predicted to polymerize Bicc1 in a left-handed helix.

168 o have reduced visuomotor skills relative to left-handed hitters.

169 lical DNA can be modeled to wrap around this left-handed HUalphabeta multimer.

170 his advantage of the left arm disappeared in left-handed human participants.

171 trating how amino acids evolved to be mostly left-handed in living organisms on Earth.

172 ) and common marmosets (Callithrix jacchus), left-handed individuals are less likely than right-hande

173 "Converted" left-handers are innately left-handed individuals forced as children to write with

174 Left-handed individuals have a deeper central sulcus in

175 An independent sample of right- and left-handed individuals showed that hand dominance affec

176 While we found significantly more left-handed individuals with atypical language lateraliz

177 ings etched in the ground-plane act as shunt left-handed inductors L(L), which suppress the surface-w

178 which can be either right-handed (Delta) or left-handed (Lambda).

179 ts, twist the ligand's pyridine rings into a left-handed (M) propeller (circular dichroism spectrosco

180 At large positive fields, both right- and left-handed magnon and two-magnon-like excitations are o

181 Although H3 nucleosomes wrap DNA in a left-handed manner and induce negative supercoils, we sh

182 In accordance with these hypotheses, left-handed marmosets were slower to explore novel foods

183 He proposed that a flat slab of left-handed material possessing an isotropic refractive

184 e direction of moving charged particles in a left-handed material.

185 Left-handed materials do not occur naturally, and it has

186 ue to the absence of both suitable all-metal left-handed materials for beam transport and suitable co

187 Left-handed materials require negative permeability micr

188 on a new class of smart materials--so-called left-handed media--that exhibit highly unusual electroma

189 gnetic polarization responses would yield a 'left-handed' medium in which light propagates with oppos

190 upport of this, many studies have found that left-handed men are overrepresented among modern profess

191 The fighting hypothesis argues that left-handed men have a negative frequency-dependent adva

192 I) folded the backbone of P into a right- or left-handed metallo-helicoid (H) with double rims.

193 previously that electromagnetic waves inside left-handed metamaterials produce negative radiation pre

194 the Earth's prebiotic organic inventory with left-handed molecules before the origin of life.

195 NA are wrapped around the core histones in a left-handed, negative superhelix.

196 In the left-handed nonepileptic subjects, there was high postte

197 a, which appears to lack the ability to bind left-handed nucleic acids.

198 are inconsistent with in vitro evidence for left-handed octameric CenH3 nucleosomes.

199 omes that display properties consistent with left-handed octamers.

200 ely 90%) preferred right-handed helices over left-handed ones, with a helix radius of approximately 0

201 bsence of ATP, MCM2-7 spontaneously adopts a left-handed, open-ring structure.

202 exists on whether subunit b adopts a classic left-handed or a presumed right-handed dimeric coiled-co

203 ules with a significant excess of either the left-handed or right-handed enantiomer.

204 eraction can be adjusted to stabilize either left-handed or right-handed Neel walls, or non-chiral Bl

205 life on Earth, that is, the predominance of "left-handed" or l-amino acids and "right-handed" or d-su

206 bers, consists of an antiparallel motif with left-handed packing angles, and it is frequently stabili

207 The two transmembrane helices form a left-handed packing arrangement with a crossing angle of

208 mann fold and the C-terminal domain adopts a left-handed parallel beta helix that is involved in coop

209 75 kDa hexamer displaying the characteristic left-handed parallel beta-helix (LbetaH) structural doma

210 s of an N-terminal uridine-binding region, a left-handed parallel beta-helix (LbetaH), and a C-termin

211 cts, revealed that LpxA contains an unusual, left-handed parallel beta-helix fold.

212 ors, revealed that LpxA contains an unusual, left-handed parallel beta-helix fold.

213 n the near zero-index passband, or the right/left-handed passband.

214 ortantly, this tendency was also seen in the left-handed patients, while it was not statistically sig

215 sue and separately analyzed right-handed and left-handed patients.

216 icult to separately analyze right-handed and left-handed patients.

217 we numerically examine optical forces inside left-handed photonic crystals demonstrating negative ref

218 isted, ribbon-like, helical filaments with a left-handed pitch and protomer nucleotide binding pocket

219 tetrameric state, the H3-H3 interface has a left-handed pitch prior to binding DNA.

220 a relatively long (approximately 1 microm), left-handed pitch that is insensitive to myosin concentr

221 the predictions of this hypothesis, however, left-handed pitchers were more successful when they were

222 Our findings reveal a novel source of left-handed plant growth caused by changes in cell wall

223 s have a significant propensity to adopt the left-handed polyproline II (P(II)) helical conformation.

224 demonstrate that urea promotes formation of left-handed polyproline II (P(II)) helical structures in

225 The left-handed polyproline II (P(II)) helix is a structure

226 The collagen triplex is made of three left-handed polyproline II (PPII) helices with each PPII

227 that (phi, psi) values corresponding to the left-handed polyproline II helix (P(II)) are preferred f

228 re reveals the presence of a surface-exposed left-handed polyproline II helix that is closely packed

229 ses a right-handed bundle of three parallel, left-handed polyproline II-type helices.

230 ndicate this small fusion module comprises a left-handed polyproline type II (PPII) helix flanked by

231 ' and the following loop up to the distorted left-handed PP(II) helix, is located at a unique positio

232 fAFP molecule is made up of six antiparallel left-handed PPII helixes, stacked in two sets of three,

233 The ribonucleocapsids were left-handed, randomly oriented, and curved inside the vi

234 Left-handed residents had fewer complications compared w

235 smonic waveguides, yields an omnidirectional left-handed response for transverse magnetic polarizatio

236 Scaling the left-handed response to higher frequencies, such as infr

237 implementation of a bulk metamaterial with a left-handed response to ultraviolet light.

238 s only recently become possible to achieve a left-handed response using metamaterials, that is, elect

239 e fabrication of resonant metamaterials with left-handed responses at frequencies beyond the visible.

240 So far, left-handed responses have typically been implemented us

241 4 tasks, and chimpanzees were classified as left-handed, right-handed, or ambidextrous.

242 attached histidine kinase domains undergo a left handed rotation within microseconds.

243 ationary at FASs, the motor complex powers a left-handed rotation of the cell around its long axis.

244 f the structures forms spiral filaments with left-handed rotations.

245 id body rather than the proposed 140 degrees left-handed screw motion.

246 s at the N-terminus of the oligomer induce a left-handed screw sense, while quaternary L-amino acids

247 they are composed of intertwined right- and left-handed single gyroids, we propose that the simultan

248 d molecular dynamics predict a tightly wound left-handed solenoid fold in which the cysteines form a

249 antea and on the left side in the sinistral (left-handed) species Biomphalaria glabrata.

250 These show that Cdt1 stabilizes MCM in a left-handed spiral open at the Mcm2-5 gate.

251 id residue critical for the formation of the left-handed spiral protein in the crystal was defective

252 d) reported herein, T-ag obd monomers form a left-handed spiral with an inner channel of 30 angstroms

253 protomers") further assemble into a low-rise left-handed staircase.

254 ate termed "P-RNA," and a highly underwound, left-handed state denoted "L-RNA." Beyond these similari

255 he right-handed bundle is in contrast to the left-handed structures obtained in previous modelling ef

256 -coil and their carboxy termini arrayed in a left-handed super-helical coiled-coil.

257 opies of the Cse4 protein and wraps DNA in a left-handed supercoil, similar to the canonical H3 nucle

258 ability of a sequence to assume the required left-handed superhelical conformation.

259 r resist uptake in nucleosomes along various left-handed superhelical pathways and to deduce the feat

260 ded DNA is tightly packed in the capsid as a left-handed superhelix and held in place by the interact

261 e find that both types of fibers fold into a left-handed superhelix that can be stabilized by positiv

262 octameric nucleosomes that organize DNA in a left-handed superhelix.

263 , the molecule multimerizes in the form of a left-handed superhelix.

264 f neighboring TPR proteins generates a novel left-handed suprahelical TPR assembly.

265 duces a right-handed helix that enriches the left-handed SWNTs for all suspended (n,m) species.

266 burn", causes diameter dilation of only the left-handed SWNTs, whose improved intermolecular interac

267 A 28yo semi-professional left handed tennis player was complaining about pain in

268 s more balanced (e.g., 67% right-handed, 33% left-handed), these cognitive representations are less e

269 Both structures are left-handed three-stranded helical filaments, revealing

270 cal twist sense changes from right-handed to left-handed through an achiral liquid-crystal phase, whe

271 The 20 lowest-energy structures show a left-handed tilt of TM3 relative to TM2 with a tilting a

272 This left-handed TM2-TM3 arrangement ensures a neatly packed

273 a moving discontinuity in a composite right/left-handed transmission line loaded with varactors when

274 We report the stereoselective synthesis of a left-handed trefoil knot from a tris(2,6-pyridinedicarbo

275 unusually consists of an extended, rod-like left-handed trimeric coiled-coil.

276 ich is at variance with the earlier reported left-handed turn structure.

277 A2 filaments with 4.4 dimers per 120 A pitch left-handed turn.

278 around which DNA wraps tightly in almost two left-handed turns.

279 Here, we report a climbing fern engaged in left-handed twining around a seed plant from the early P

280 olved long central domain with 90 degrees of left-handed twist and near 2-fold symmetry.

281 Most of the CC structure has a left-handed twist with heptad repeats, but both coil 1B

282 ion indicates that normal VCD fibrils have a left-handed twist, whereas reversed VCD fibrils are flat

283 a helical pitch of approximately 410 A and a left-handed twist.

284 light (CPL) induces the formation of right- (left-)handed twisted nanoribbons with an enantiomeric ex

285 growth of petal epidermal cells, leading to left-handed twisted petals.

286 that MreB double protofilaments can exhibit left-handed twisting that is dependent on the bound nucl

287 Each repeat forms a left-handed, two-helix bundle that presents an RVD-conta

288 nus: the tertiary amino acid L-Val induces a left-handed type II beta-turn in both the solid state an

289 History A 36-year-old left-handed woman with a history of developmental delay

290 of the nucleosomal DNA, a consequence of its left-handed wrapping around the histone octamer.

291 on in the lifetime of the canonical state of left-handed wrapping.

292 Since its discovery in 1979, left-handed Z-DNA has evolved from an in vitro curiosity

293 res, such as the four-stranded G-quadruplex, left-handed Z-DNA, cruciform and others.

294 a transition between right-handed B-form and left-handed Z-form DNA under controlled supercoiling.

295 The sequence crystallizes as a left-handed Z-form double helix with Watson-Crick base p

296 similar to those of the naturally occurring left-handed Z-form of DNA.

297 sion of multiple regions of genomic DNA into left-handed Z-form.

298 same duplex DNA between right-handed B- and left-handed Z-forms leads to a diode-like switch in spin

299 two alternative configurations, including a left-handed Z-RNA conformation and a compact purine Trip

300 NA conformation and a destabilization of the left-handed Z-RNA.