ライフサイエンスコーパス: left-right axis

1 eages and birth positions with regard to the left-right axis.

2 of nervous systems are asymmetric about the left-right axis.

3 ymmetry in nodal family signaling across the left-right axis.

4 eral somite formation is regulated along the left-right axis.

5 e plays a key role in establishing the avian left-right axis.

6 rn correlates with normal development of the left-right axis.

7 gastrulation for proper establishment of the left-right axis.

8 hat mature GDF1 is sufficient to reverse the left-right axis.

9 terning events that establish the vertebrate left-right axis.

10 o is initially broken to define a consistent left-right axis.

11 le cilia, affecting the establishment of the left-right axis.

12 ms that allow embryos to reliably orient the left-right axis.

13 left-right organizer, which establishes the left-right axis.

14 d AVSDs only concurrently with heterotaxy, a left/right axis abnormality.

15 LIC is required for the establishment of the left-right axis and for normal expression of Nodal, and

16 n protein family in the establishment of the left-right axis and in the formation of Kupffer's vesicl

17 tinoic-acid signalling is uniform across the left-right axis and occurs in node ectoderm but not node

18 eading to the establishment of the embryonic left-right axis are well known, less is known about the

19 rically, neurons must be specified along the left-right axis, assigned left-side versus right-side id

20 ared co-receptor Cryptic to specify visceral left-right axis asymmetry.

21 xes, it is symmetrically expressed along the left-right axis at early stages of embryonic and cardiac

22 own to be asymmetrically expressed along the left-right axis before the development of organ asymmetr

23 manipulations in any vertebrate by which the left-right axis can be reliably controlled.

24 d homeobox gene, plays a crucial role in the left-right axis determination and dextral looping of the

25 ctivation of KIF3A produces abnormalities of left-right axis determination and embryonic lethality.

26 rate that Pitx2c plays a crucial role in the left-right axis determination and rightward heart loopin

27 l patterning of the spinal cord, a defect in left-right axis determination and severe polydactyly (ex

28 Dyneins have been implicated in left-right axis determination during embryonic developme

29 When errors in left-right axis determination happen, they almost always

30 nge of biological responses, from control of left-right axis determination in embryonic development t

31 ese genes was not associated with defects in left-right axis determination in humans or zebrafish.

32 f8 and Sonic Hedgehog genes are required for left-right axis determination in the mouse embryo, but t

33 imately govern gut formation and patterning, left-right axis determination, and development of the ce

34 ardiac development and upstream processes of left-right axis determination, and to consider how pertu

35 Furthermore, left-right axis determination, neural induction and somi

36 ole in several mammalian processes including left-right axis determination, sperm motility, and photo

37 PHP to PKD, to primary cilia function and to left-right axis determination.

38 Pitx2 also has a postulated role in left-right axis determination.

39 nr-1 expression per se is a causal factor in left-right axis determination.

40 ermore, PCSK6 is a protease that cleaves the left-right axis determining protein NODAL.

41 which cilia function contributes to cardiac left-right axis development and discuss the latest findi

42 te genes have emerged from recent studies of left-right axis development in chick, frog and mouse, wh

43 genes required for the establishment of the left-right axis during early development.

44 Specification of the left-right axis during embryonic development is critical

45 node have been implicated in initiating the left-right axis during embryonic development, but how ci

46 alyses, we investigated the initial steps of left-right axis establishment in embryos of a Dnah5 muta

47 ene family acting at different points during left-right axis establishment.

48 ole of EGF-CFC genes and Nodal signalling in left-right axis formation is conserved from fish to huma

49 Defects in embryonic left-right axis formation represent a significant portio

50 e exhibited a spectrum of defects related to left-right axis formation, including visceral situs inve

51 al roles in embryonic development, including left-right axis formation.

52 m induction and asymmetric expression during left-right axis formation.

53 ated in dorsoanterior development, initiates left-right axis formation.

54 Abnormal left-right-axis formation results in heterotaxy, a multi

55 onal patterning, providing new insights into left/right axis formation.

56 rrhage, structural cardiac defects, abnormal left-right axis, hepatorenal and pancreatic cysts, and e

57 ellite symposium on 'Making and breaking the left-right axis: implications of laterality in developme

58 l organs are consistently oriented along the left-right axis in all vertebrates, and perturbations of

59 ligands, and are involved in regulating the left-right axis in chick, mouse and zebrafish.

60 Furthermore, the orientation of the left-right axis in conjoined twins is dependent upon whi

61 ght asymmetries, or can "rescue" a perturbed left-right axis in conjoined twins to normal orientation

62 Nodal flow orients the left-right axis in some vertebrates, and is generated by

63 ile cilia and is required for patterning the left-right axis in vertebrates.

64 hat its activity is necessary to specify the left-right axis in Xenopus and zebrafish embryos.

65 specification program that occurs across the left/right axis in the nervous system of the nematode C.

66 Formation of the left-right axis involves a symmetry-breaking signal orig

67 Development of asymmetry along the left-right axis is a critical step in the formation of t

68 of internal organs asymmetrically along the left-right axis is critical for their proper adult funct

69 The establishment of the left-right axis is crucial for the placement, morphogene

70 Establishment of the left-right axis is essential for normal organ morphogene

71 three-dimensional vertebrate body plan, the left-right axis is linked to the dorsoventral and anteri

72 The vertebrate left-right axis is specified during embryogenesis by a t

73 Functional diversification across the left/right axis is a common feature of many nervous syst

74 Human mutations in ZIC3 are associated with left-right axis malformations (MIM 306955, 208530, 20710

75 ne pitx2 isoform, pitx2c, in determining the left-right axis of amphibian embryos, we examined the he

76 integrin receptor in the development of the left-right axis of asymmetry in vertebrates.

77 ogy leading to a failure in establishing the left-right axis of asymmetry.

78 interactions regulate the development of the left-right axis of asymmetry; however, the identities of

79 known about molecular cues that specify the left-right axis of the body, fashioning the asymmetric m

80 tions with other molecular components of the left-right axis pathway.

81 ctions of cilia in diverse processes such as left-right axis pattern formation, cerebrospinal fluid f

82 in associated with cystic kidney disease and left-right axis patterning defects in the mouse.

83 e heart was long thought to be restricted to left-right axis patterning during embryogenesis.

84 Dawid focus on the role of FGF signaling on left-right axis patterning, showing that FGF functions a

85 ed, the embryonic mechanism that orients the left-right axis relative to the dorsoventral and anterop

86 identified by wall thickness linked to a LV left-right axis shift and a decrease in short-axis eccen

87 The LV left-right axis shift was not reversible post-aortic val

88 pression of Vg1 protein can fully invert the left-right axis (situs inversus), can randomize left-rig

89 how the cilia protein Arl13b is required for left right axis specification as its absence results in

90 the mouse node is instrumental in initiating left-right axis specification and identify Nodal as the

91 ncanonical Wnt signaling with the control of left-right axis specification, and provide an entry poin

92 y central roles in mesendoderm induction and left-right axis specification, but the mechanisms regula

93 ide spectrum of phenotypes, including random left-right axis specification, polycystic kidney disease

94 mesoderm formation, anterior patterning, and left-right axis specification.

95 ion, anterior-posterior axis orientation and left-right axis specification.

96 terior-posterior axis, neural patterning and left-right axis specification.

97 a key regulator of mesoderm development and left-right axis specification; components for nervous sy

98 ymmetry, is a key feature of the human brain left-right axis supporting functional processes, such as

99 ntric (i.e., environment-based) space on the left-right axis, where spatial discriminations (like "b"

100 rates develop distinct asymmetries along the left-right axis, which are consistently aligned with the