ライフサイエンスコーパス: lessen

1 -Asp19Gly, although the antiviral effect was lessened.

2 .0005), and secondary astigmatism (P < .005) lessened.

3 racial disparities in clinic attendance were lessened.

4 er injury the adverse effects of obesity are lessened.

5 CCL2/MCP-1, hMMP7, and hTNF-alpha, were also lessened.

6 ivation of 5-HT1A autoreceptors, which would lessen 5-HT neuron firing, contributes to cocaine-seekin

7 presented in an accompanying appendix do not lessen a paper's impact.

8 aque environment, reduced neuroinflammation, lessened Abeta load, and ameliorated cognitive deficits.

9 p of the beta-hairpin, was attributable to a lessened ability of these variants to insert into membra

10 e results indicate that silver ion sinks may lessen AgNP impacts on natural microbial ecology relativ

11 in levels, reduced bacterial overgrowth, and lessened alcoholic steatohepatitis.

12 Blockade of OX40L significantly lessened allergic responses to HDM or peanut.

13 sis services in India and South Africa could lessen, although not eliminate, the catastrophic financi

14 ce of galectin-8, pericentrin compactness is lessened and mitotic microtubule length is shortened, as

15 imit genetic growth potential appear to have lessened, and variation in height by socioeconomic posit

16 osage or aspirin addition to other drugs may lessen antithrombotic protection.

17 almitoylation and ERK phosphorylation, while lessening apoptosis in HPHG treated ECs.

18 is compressed into the last years of life or lessened as people age.

19 Shared genetic influence lessened as the distance between depth measurements was

20 as in NIHSS scores was observed but this has lessened as the documentation of NIHSS has improved in r

21 on in turn was limited as a consequence of a lessened availability of nuclear-localized signal transd

22 inding motif or Atp8b1 gene transfer in mice lessened bacteria-induced lung injury and improved survi

23 To lessen barriers and facilitate renal transplantation, bl

24 , whereas removal of just iron significantly lessens binding.

25 dihydroxylethersatrienoic acids (DHETs) with lessened biological effects.

26 tillation ameliorated bladder hyperactivity, lessened bladder mucosa damage, and decreased interstiti

27 n, diminished tumor-mediated osteolysis, and lessened bone density decrement in mice injected with br

28 e progression of cerebrovascular disease and lessen both the frequency and impact of ischemic events.

29 ockdown improved brain function recovery and lessened brain contusion volume after trauma.

30 These barriers may be lessened by greater education of the public and health c

31 quasi-reversible, and that it can be greatly lessened by simple modifications of the solar cell opera

32 trogenic hypoglycemia in T1D humans could be lessened by targeting metabolic pathway(s) associated wi

33 The strength of these findings is lessened by the lack of systematically collected data us

34 the SNP for response or side effects was not lessened by the presence of cognitive impairment.

35 ogenesis by sulfate-reducing bacteria may be lessened by the presence of large labile DOC pools that

36 y increased median survival of mice with HF, lessened cardiac fibrosis, reduced gene expression of se

37 lessens the severity of the HF phenotype by lessening cardiac fibrosis, improving molecular and stru

38 In wild-type cells, Jak1 degradation lessens CD4+ cell sensitivity to cytokines during TCR st

39 Moreover, depletion of fibrinogen lessened cerebral amyloid angiopathy pathology and reduc

40 A variety of treatment approaches aimed at lessening chemoreceptor-driven sympathetic overactivity

41 choline supplementation might significantly lessen cognitive dysfunction in DS and reduce cognitive

42 abnormalities in this region could result in lessened concern (frequently ascribed to minimization an

43 on was not better than either agent alone in lessening confirmed Expanded Disability Status Scale pro

44 advantages of an AV fistula attempt strategy lessened considerably among older patients, particularly

45 B influenza preexposure, and the correlation lessened considerably over time.

46 d postoperatively may improve acute pain and lessen conversion to chronic pain.

47 outcomes, improves future independence, and lessens costs from provincial and societal perspectives.

48 an prevent ROS release from the active site, lessen damage to the protein, and produce higher total t

49 that reducing greenhouse gas emissions could lessen damages by $1.3 billion this century.

50 alpha (PSKalpha) for delaying senescence and lessening decay in strawberry fruits during storage at 4

51 g imaging with high-speed detectors, thereby lessening demands on cryostage precision and stability.

52 ss of compound is worthy of further study to lessen diabetes complications but that dosage needs cons

53 at lower but not higher doses, significantly lessens diabetes-associated atherosclerosis with reducti

54 we found that BAPMA had a greater ability to lessen dicamba volatilization than DMA or DGA.

55 Recent show line selection might have lessened differences in impulsivity between breeds.

56 ment with an antibiotic and CC-3052 not only lessened disease but also improved bacterial clearance f

57 Interventions that lessen disparities in adherence may be more effective in

58 ities in suppression than interventions that lessen disparities in constancy.

59 for both attendance measures, the impact of lessening disparities in adherence may be overstated.

60 Lessening disparities in adherence or constancy lowered

61 P values can be reframed to lessen distortions by presenting them without reference

62 resulted in increased bacterial efflux pumps lessening drug concentrations, up-regulated enzymes modi

63 riceal eradication as rapidly as possible to lessen early rebleeding while minimizing ligation-induce

64 Results suggest lessened enthusiasm for genetic information that maintai

65 m prophylaxis after a first manic episode to lessen episode recurrence, allow cognition to recover to

66 -disordered breathing treatment may somewhat lessen ethnic stroke outcome disparities.

67 Rising temperatures and lessening fresh water supplies are threatening agricultu

68 Our results suggest that insulin resistance lessens fuel toxicity in the stressed heart.

69 missions offers an additional opportunity to lessen future climate change.

70 limentary plastic film efficacy to remove or lessen HAs content in polluted wines; and ii) to evaluat

71 address the growing demand for eye care and lessen healthcare disparities for patients.

72 lt in improved glucose tolerance and notably lessened hepatic steatosis in the mouse model.

73 accompanying mitochondrial superoxide levels lessens hyperalgesia and LTP induction.

74 ferential insulin analogs), should therefore lessen hypoglycemia.

75 that portal (Po) vein insulin delivery would lessen hypoglycemia.

76 The Dexmedetomidine to Lessen ICU Agitation (DahLIA) study was a double-blind,

77 Blockade of type 1 interferon significantly lessens IL-10 and PD-1/PD-L1, allows normal secondary ly

78 countermeasures to preserve muscle function, lessen illness, and hasten the recovery of critically il

79 Furthermore, repression was significantly lessened in a mutant unable to produce propionyl-CoA, wh

80 change in vessel diameter following FUS was lessened in amyloid coated vessels.

81 n and liver lipid accumulation were markedly lessened in Lcn2(-/-) mice.

82 m aggregate growth rate decreased due to the lessening in the available surface of the HemNPs that CN

83 ntervention can have broad consequences that lessen inequalities in achievement and health.

84 genetic inhibition of apoptosis and necrosis lessens infarct size and improves cardiac function in th

85 whether the inhibition of JAK function might lessen inflammation in murine models of the disease.

86 rapeutic or dietary interventions that could lessen inflammation in this disease could significantly

87 depletion therapy for joint arthritis flares lessens inflammation by increasing lymphatic drainage an

88 or ruxolitinib dampens T-cell activation and lessens inflammation in a model of HLH in which perforin

89 In summary, rhADAMTS13 lessens inflammation in allografts by reducing NET burde

90 ng and extensive degradation of PG fragments lessen inflammatory responses and may be advantageous fo

91 onstantly intervening God in the Middle Ages lessened interest in the inherent features of nature tha

92 trate aerosols would improve air quality and lessen interference with the hydrologic cycle, but lead

93 ptic nerve head morphology and significantly lessened intraocular pressure elevation.

94 that constitutive activation results from a lessened intrinsic barrier that restrains spontaneous co

95 detectable analytes and has the potential to lessen ionization matrix effects in ADI-MS analyses.

96 They lessen ischemic tissue injury by serving as endogenous b

97 enhance this effect, and might have actually lessened it.

98 ation and development of an active phase and lessen its intensity.

99 vent LID and very few drugs are available to lessen its severity, thus representing a major clinical

100 del, not BMSCs but adult HCs transplantation lessened liver injury, recovered liver function and resc

101 y fibrosis, ablates NF-kappaB signaling, and lessens matrix deposition.

102 all had reduced demyelination accompanied by lessened microglial and polydendrocyte cellular reactivi

103 peutics, which, in turn, will hopefully help lessen misuse of opioid pain medications and address the

104 vailable, reducing violence in drug markets, lessening misuse of legal pharmaceuticals, preventing dr

105 ng an inverse agonist of these receptors may lessen motor symptoms.

106 C5a receptor deficiency, which also lessens myeloid-derived suppressor cells in the premetas

107 Erythropoietin (Epo) has potential to lessen neurologic sequelae due to hypoxia-ischemia.

108 tial task-related activation was followed by lessening of activation in prefrontal cortex, premotor c

109 y restored the WT phenotype, which suggested lessening of amino acid clashes in heterotetrameric chan

110 These defects reflect a true lessening of associative memory strength, as distortions

111 se in astrogliosis was also witnessed in the lessening of severity of EAE clinical scoring, indicatin

112 stration that SMN2 trans-splicing leads to a lessening of the severity of the SMA phenotype and provi

113 in the SHUV pigment is attributed to the (i) lessening of the steric restraints near the beta-ionone

114 Although decision regret appears to lessen or dissipate with time, study on larger numbers o

115 eficial to the macaques, which in return may lessen or extinguish the remarkable foraging technology

116 Necroptosis-inhibiting drugs may lessen organ damage during invasive pneumococcal disease

117 c patterns at broad scales; this interaction lessens our ability to confidently ascertain native vs.

118 LOR-PCI (Tailored Antiplatelet Initiation to Lessen Outcomes due to Decreased Clopidogrel Response Af

119 Maternal guilt was common, but usually lessened over time.

120 to autoxidize in vitro did not substantially lessen overall H(2)O(2) formation.

121 e long been known to buffer ROS activity and lessen oxidative perturbations during exercise.

122 xidant defenses is an important mechanism to lessen oxidative stress and inflammation.

123 Lessening oxidative damage to DNA and telomerase express

124 ted in significant increases in survival and lessened pathology.

125 tical as we attempt to better understand and lessen persistent child asthma disparities.

126 This lessened perturbations in expression of endothelial biol

127 ng Akt1 expression specifically in VSMCs may lessen plaque progression.

128 osclerosis throughout the vascular tree, and lessened plaque inflammation.

129 berry intake improved antioxidant status and lessened plasma interleukin (IL)-6 (0.3-fold of control,

130 sure did not prevent pore initiation but did lessen pore enlargement.

131 as-phase conversion of large molecules while lessening possible memory effects.

132 Synergistic drug combinations can lessen potential toxic side effects through lower dosing

133 rs previously (RR 0.29), with risk reduction lessening progressively as the time since the last birth

134 eactive oxygen species with N-acetylcysteine lessened protein aggregation and decreased apoptosis, su

135 and oxidized-LDL to levels similar to lean; lessened protein carbonyls and interleukin (IL)-6.

136 The intervention aimed to lessen psychological perceptions of threat on campus by

137 This finding was driven primarily by the lessened psychological value that more conservative indi

138 GSK3beta might serve as a unique strategy to lessen pulmonary inflammation.

139 ligases might serve as a unique strategy for lessening pulmonary inflammation.

140 riments established that PKA phosphorylation lessens rectification of I(SK) via reduction Ca(2+) /vol

141 lockade of the N- and L-type calcium channel lessens renal injury in kidney disease patients.

142 We speculate that this lessens repression of dpp dorsally, and thus creates a p

143 The lessened response after repeated exposure, likely driven

144 osure to noise could lead to a heightened or lessened response.

145 Tumor-associated edema and necrosis were lessened, resulting in increased perfusion and reduced d

146 ight be amenable to interventions that could lessen risks and help to prevent future child deaths.

147 once a diagnosis has been made, not only to lessen risks for comorbidities, but also to avoid aggrav

148 Melatonin supplementation has been shown to lessen SCI, but its use has been limited by its side eff

149 yramidal cells and interneurons considerably lessens seizure severity by decreasing cortical excitabi

150 eased the robustness of the oscillator, with lessened sensitivity to changes in cyclin synthesis rate

151 ut available disease-modifying therapies can lessen severity and delay progression.

152 inhibitor targeting Fbxo3 was sufficient to lessen severity of cytokine-driven inflammation in sever

153 Vaccination can reduce illness and lessen severity of infection.

154 Inappropriate Scenarios for Echocardiography Lessen Significantly) control group.

155 ions may be a potent psychological lever for lessening societal inequality.

156 gical causes increased treatment support and lessened stigma.

157 diminishes myelin basic protein abundance by lessening stimulation of the exchange protein directly a

158 around the world to improve cancer care and lessen suffering for patients worldwide.

159 Serving as decoys, receptor mimics may lessen symptoms while avoiding the use of antibiotics.

160 , while comorbid, poorly controlled diabetes lessened that risk.

161 These pectin structural changes may lessen the ability of the cell wall to undergo stress re

162 c acid receptor antagonist (AGN193109) could lessen the anterior transformation phenotype and rescue

163 n, an impaired endothelial NO response could lessen the benefit of RAS inhibition in diabetic renal d

164 function presents an exciting opportunity to lessen the burden of disease in these patients.

165 t in developing accurate prediction tools to lessen the burden of experimental work and cope with the

166 s non-cardia cancer risk in minorities could lessen the burden of gastric cancer.

167 more research is urgently needed in order to lessen the burden of macrovascular complications of type

168 tion of these data is therefore paramount to lessen the burden of storage and facilitate its dissemin

169 This intervention may lessen the burden of stress-related symptoms in family m

170 interactions may lead to innovative ways to lessen the burden of this common childhood disease.

171 It would also lessen the chances of exposing patients to treatments th

172 ancy-based ventilation have the potential to lessen the climate impact of surgical services without c

173 selective effects, meaning that warming will lessen the consequences of introductions in the future a

174 here is no effective treatment to prevent or lessen the consequences of neonatal H-I.

175 r encephalopathies of other etiologies-would lessen the controversy considerably, as the attribution

176 cle system provide a promising new avenue to lessen the debilitating motor symptoms of HD.

177 treatment of mice with established HF could lessen the detrimental phenotype associated with pressur

178 Here we explore ways to lessen the divide between LMICs and high-income countrie

179 ng, evaluating, and scaling interventions to lessen the economic burden and inconvenience of ANC.

180 elty and/or oral beta-adrenergic agonists to lessen the effects of Abeta accumulation during aging.

181 sistance are the two ways in which hosts can lessen the effects of infection.

182 Countermeasures that lessen the effects of unloading include physical activit

183 tumor response and frequently contributes to lessen the efficacy of immunotherapeutic approaches.

184 for in vitro testing in various settings, to lessen the experimental burden and perform more targeted

185 Additional resources were perceived to lessen the impact of lost earnings, help offset costs as

186 in C supplementation to pregnant smokers can lessen the impact of maternal smoking on offspring pulmo

187 pain, foot conditions and interventions that lessen the impact of rheumatic diseases.

188 demand for shark deterrents and measures to lessen the impact of shark bites on humans.

189 lastly discuss potential countermeasures to lessen the impact of sleep inertia.

190 nhibiting COX-2 during lactation weaning may lessen the incidence of breast cancer metastasis.

191 vation of kidney function early after LT may lessen the incidence of CVE, which are an independent pr

192 nterventions with translational potential to lessen the incidence of these deleterious immune respons

193 -5p may serve as a compensatory mechanism to lessen the increase in FGF9 and prevent aberrant lung de

194 ly, and consider the importance of timing to lessen the inherent risks of each procedure.

195 liver would increase hepcidin expression and lessen the iron loading in both models.

196 rence to evidence-based recommendations will lessen the morbidity and mortality associated with febri

197 ourse regimen has potential to substantially lessen the multidrug-resistant tuberculosis epidemic, bu

198 ourse regimen has potential to substantially lessen the multidrug-resistant tuberculosis epidemic, bu

199 These results do not lessen the need for further studies, continuous self-reg

200 e as a whole, these true 'genomic medicines' lessen the need for precision approaches to individualiz

201 ent blood management need to be developed to lessen the need for transfusion--eg, by early identifica

202 Proton radiotherapy (PRT) may lessen the neuropsychological risk traditionally associa

203 beetroot and beetroot juice, are reported to lessen the oxygen cost of exercise, increase efficiency,

204 Reduced drug exposure might lessen the possibility of drug-related adverse events an

205 eptable by adopting risk-managed routes that lessen the potential to adversely impact high-quality gr

206 testing of each specimen may be advisable to lessen the probability of underestimating an individual

207 c and probiotic therapy has the potential to lessen the public health burden of antimicrobial-associa

208 y kidney failure, reduce the symptom burden, lessen the risk of cardiovascular complications, and pro

209 understand their natural biology in order to lessen the risk of collateral harm and avoid the crisis

210 than invasive biopsy is important as it will lessen the risk of infection and other stresses, while r

211 Presence of immune recovery may lessen the risk of postoperative ocular complications.

212 mentation >= 3 months prior to pregnancy may lessen the risk of PTD associated with PM exposure durin

213 o therapeutic interventions are available to lessen the risk of the development of the haemolytic ura

214 xpayer dollars in biomedical research and to lessen the risk required for industry partners to make s

215 thermia, without systemic hypothermia, could lessen the severity of AP induced by different methods i

216 posure to bleaching in 1998 and 2002 did not lessen the severity of bleaching in 2016.

217 s, should it become achievable, would likely lessen the severity of nephrotic syndrome in patients ca

218 gies to control the USA300 SSTI epidemic may lessen the severity of the concurrent USA300 BSI epidemi

219 ay negatively regulate VSMC proliferation to lessen the severity of the lesion.

220 ough associated with larger economic losses, lessen the social-psychological impact of job loss.

221 of omics compression algorithms designed to lessen the storage burden and facilitate the exchange an

222 s to California's flammability standards may lessen the use of other flame retardants and similarly r

223 ound C or AMP-activated protein kinase siRNA lessened the activation of Jun N-terminal kinase, extrac

224 s well as antibody incubations significantly lessened the background compared with including only the

225 e JAK1/2 inhibitor ruxolitinib significantly lessened the clinical and laboratory manifestations of H

226 e-groups to the low-risk programme typically lessened the cost-effectiveness.

227 totoxicity in HT-29 cells, and significantly lessened the DON-stimulated intracellular reactive oxyge

228 3T3-L1 adipocytes, knockdown of PFKFB3/iPFK2 lessened the effect of PPARgamma activation on stimulati

229 The exogenous GSH treatment clearly lessened the HT stress by increasing the above variables

230 and mineralocorticoids neither augmented nor lessened the hypertrophic response.

231 vide pain relief (over avoid analgesic risk) lessened the likelihood that parents would withhold the

232 , transplantation of WT BM into N1(+/-) mice lessened the myocardial injury observed in N1(+/-) mice.

233 Medication then reduced symptoms and lessened the need for compensation, thereby normalizing

234 50%, decreased the number of dying neurons, lessened the number of activated microglial cells, prote

235 r adding the reducing agent, dithiothreitol, lessened the response.

236 ween GPIbalpha and GPIbbeta subunits further lessened the restraint of GPIbbeta on GPIbalpha shedding

237 ptotic and inflammatory effects of IL-33 and lessened the severity of lung injury in mouse models of

238 njected intraperitoneally, TRPV4 antagonists lessened the severity of myotonia in vivo by approximate

239 h a reactive oxygen species scavenger, which lessened the severity of the blood phenotype.

240 The Fbxo3 inhibitors effectively lessened the severity of viral pneumonia, septic shock,

241 Endotoxemia lessened the tyramine-induced reduction in leg vascular

242 ofessional oncology society, is committed to lessening the burden of cancer and as such will promote

243 ncer disparities is critically important for lessening the burden of cancer.

244 rs2294918 E434K decreased PNPLA3 expression, lessening the effect of the I148M variant on the predisp

245 otransmitter release in presynaptic neurons, lessening the effects of demyelination.

246 d novel vaccine formulations are critical in lessening the impact of both pandemic and seasonal influ

247 naturally occurring reactive metals, thereby lessening the impacts of matrix diffusion on sustaining

248 y be an effective treatment in inhibiting or lessening the inflammatory response mediated through TLR

249 odeling as a triage point at the laboratory, lessening the need for laboratory-based CD4(+) T cell co

250 also serves to distribute the impact force, lessening the potential of detection by a mammalian host

251 preoperatively continues to be important in lessening the risk of postoperative inflammation and com

252 ed FBXL2 actions by stabilizing CCTalpha and lessening the severity of inflammatory lung injury.

253 Lessening the structural ambiguity would lead to further

254 e the fracture resistance of lithiated Si by lessening the tensile stress concentrations in Si struct

255 ous modified dosing regimens with the aim of lessening the treatment burden associated with monthly i

256 Stable knockdown of elevated SENP7L levels lessens the dissemination of highly metastatic BCa cells

257 bly due to a hostile host brain environment, lessens the effectiveness of this approach.

258 orelimb (NPT) following a unilateral infarct lessens the efficacy of rehabilitative training, and red

259 s the robustness of the progenitor state and lessens the impact of unequal, random distribution of mo

260 In conclusion, the results suggest that Pf lessens the inflammatory phenotypes of LPS-activated neu

261 -yl)-1,2,4-thiadiazolidine-3,5-dione (NP12), lessens the magnitude of adverse myocardial remodeling a

262 motes anorexia and that PACAP preferentially lessens the maintenance of feeding in rats, effects oppo

263 Enhancing skin allograft longevity lessens the need for new allografts before optimal inter

264 Inhibiting this self-propagating pathway lessens the overall inflammatory burden, which may alter

265 tamin D/high-calcium (2%)/lactose (20%) diet lessens the phenotype, and knockout pups fostered to mot

266 a sufficient dose reaches the target tissue, lessens the potential for off-target side effects, and c

267 sociation of toluene with the catalyst which lessens the relative importance of the uncatalyzed backg

268 iconductor-insulator-metal interface greatly lessens the scattering loss, and more importantly, effic

269 hemoglobin (HbF, alpha(2)gamma(2)) in adults lessens the severity of sickle cell disease (SCD) and th

270 oves the prognosis of the tooth, but it also lessens the severity of the disease condition.

271 ratrol treatment of mice with established HF lessens the severity of the HF phenotype by lessening ca

272 ebral-ventricular space in SMA neonates also lessens the severity of the SMA phenotype in a severe SM

273 arents who exercise good smoking hygiene can lessen their child's risk of developing plaque.

274 rmation, whereas numbers needed to treat can lessen their understanding.

275 d support from local leaders, which may have lessened their success.

276 ntensive perioperative steroid treatment can lessen these complications.

277 riate devices and supporting services) might lessen these concerns.

278 To lessen these effects, we have encapsulated an anti-cance

279 rs, because the Rho inhibitor C3 transferase lessened these effects.

280 ontinuation of immunosuppressive drugs could lessen this burden, but the safety, applicability, and c

281 Various methods have been developed to lessen this requirement, but there are still three tasks

282 ant that cannot translocate within dendrites lessened this activity-dependent synaptic plasticity.

283 HIT and identifies potential new targets for lessening this risk.

284 nal damage and the use of blue-blocking IOLs lessens this damage.

285 PA, attenuated ICH, lowered plasma d-dimers, lessened thrombocytopenia, and improved neurologic outco

286 ogical selection, although these differences lessened through time, likely due to high dispersal rate

287 e tumor perivascular niche, which eventually lessens tumor initiation and progression in vivo and in

288 ighlight the molecular action of the agents, lessen unwarranted apprehension about the transmissibili

289 ss in obese men and dietary modification can lessen urgency, nocturia, and incontinence.

290 es during warm seasons, which is removal and lessening versus enhancement of air pollution.

291 activity levels through young adulthood may lessen weight gain as young adults transition to middle

292 t different subtypes of influenza viruses by lessening weight loss and lowering viral loads.

293 age species indicated that "wait times" were lessening where changes were detected.

294 This tedious and time-consuming work can be lessened with automatic Question Answering (QA) systems,

295 trade-offs are expected to be significantly lessened with CNF manufacturing maturity.

296 th dexmedetomidine but the occurrence may be lessened with low dose.

297 These limitations might be lessened with next-generation RNA sequencing (RNA-seq).

298 uence of predisposing factors for second AMI lessened with time after the initial event.

299 In patients, muscle stiffness lessens with exercise, a change known as the warmup phen

300 using us to speculate that T-cell activation lessens with time.