ライフサイエンスコーパス: lethally

1 l blood parasite loads were observed between lethally and nonlethally infected animals at 12 dpi.

2 cted in waterways at concentrations that are lethally and sublethally toxic to aquatic organisms.

3 sible to compare physiological parameters in lethally challenged animals and survivors.

4 crificed for analysis of immune responses or lethally challenged by intranasal inoculation with vacci

5 Clinical signs in the lethally challenged mice included seizures, convulsions,

6 The immunized mice were lethally challenged with C. posadasii through either an

7 up to 6 h after viral inoculation) with mice lethally challenged with HSV-2 delayed disease onset and

8 were vaccinated with VSVDeltaG/Dual and were lethally challenged with ZEBOV or ANDV.

9 Lethally conditioned mice received transplants of major

10 survive doses of total-body irradiation that lethally deplete hematopoietic progenitor populations in

11 We rescued cells lethally depleted of endogenous Cdk1 with an exogenous C

12 In microbes lacking an OM, MRL-494 lethally disrupts the cytoplasmic membrane.

13 nhanced ZIKV and DENV infection in vitro and lethally enhanced DENV disease in mice.

14 gases, where susceptible persons may develop lethally high body temperatures.

15 not altered in wild-type animals exposed to lethally high H2S or in hif-1(ia04) mutants that die whe

16 antiretroviral deoxycytidine deaminase that lethally hypermutates human immunodeficiency virus type

17 creased iron availability in serum occurs in lethally ill ICU patients and should trigger prospective

18 This virus is unique in its ability to lethally infect both mammals and insects.

19 dy, we compared the host immune responses of lethally infected and vaccinated mice to highlight the h

20 Strikingly, monocytes from lethally infected animals produced significant amounts o

21 elecoxib treatment prolonged the survival of lethally infected animals.

22 ion of IL-1beta production by monocytes from lethally infected cattle compared to those from nonletha

23 nti-inflammatory agents in protection of the lethally infected mice by H1N1 or H5N1 influenza viruses

24 and temporal changes in NK and NKT cells in lethally infected mice correlated with higher NK cell cy

25 Unexpectedly, depletion of neutrophils from lethally infected mice enhanced bacterial elimination, d

26 Lethally infected mice given influenza virus-specific CD

27 lethally infected mice, splenic T cells from lethally infected mice produced significantly lower leve

28 In contrast, non-lethally infected mice showed polarization of M2 macroph

29 leukocytes were isolated from the brains of lethally infected mice, 88% of these cells were identifi

30 nti-capsular 3E5 MAb prolong the survival of lethally infected mice, whereas the 3E5 IgG3 MAb does no

31 ot sufficient to provide early protection to lethally infected mice.

32 D4 T cells protected a significant number of lethally infected RAG(-/-) mice, demonstrating the prote

33 Furthermore, compared to lethally infected sham controls, neutrophil depletion in

34 of PD-1 significantly increased survival of lethally infected wild-type mice.

35 on of the neutralizing IgM MAb to A/JCr mice lethally infected with B. anthracis strain Sterne had no

36 d KC significantly enhanced survival of mice lethally infected with C. albicans.

37 Sixteen rhesus monkeys were lethally infected with MARV or RAVV and treated with NP

38 ceptor 11, which is absent in humans, can be lethally infected with S. Typhi, a breakthrough that pro

39 Lethally-infected mice showed accumulation of M1 macroph

40 Predominance of M1 macrophages in lethally-infected mice was associated with expansion of

41 ,3-dimethyl-1-butanol (DMB), is shown to non-lethally inhibit TMA formation from cultured microbes, t

42 positive astrocytes in the hippocampus of 26 lethally intoxicated drug addicts and 35 matched control

43 (C57BL/6 + SJL/J) after transplantation into lethally irradiated (8.5 Gy) BALB/c recipients (H2(d)).

44 ing human APOE3/3 or APOE4/4 donor mice into lethally irradiated 5-month-old APPswe/PS1DeltaE9 mice.

45 homozygous deficient for EP2 (EP2(-/-)) into lethally irradiated 5-month-old wild-type or APPswe-PS1D

46 nsplanted uniparental fetal liver cells into lethally irradiated adult mice to test their capacity to

47 es multilineage hematopoietic engraftment of lethally irradiated adult mice.

48 t HSC that engraft upon transplantation into lethally irradiated adult mice.

49 These progenitors engraft lethally irradiated adults and contribute to long-term,

50 lanted with 1 x 10(7) bone marrow cells into lethally irradiated AKR/J recipients.

51 ted mouse bone marrow or purified HSCs, into lethally irradiated allogeneic recipients and determined

52 m GKO donor mice induced more severe GVHD in lethally irradiated allogeneic recipients compared to th

53 transfer of the G9C8 clone or by chimerizing lethally irradiated ALR or reciprocal (ALR x NOD)F1 reci

54 Recipient C57BL/6 (H2b) mice were lethally irradiated and given transplants of bone marrow

55 Subsequently, the mice were lethally irradiated and received lymphocytes including m

56 Eight-week-old BXSB mice were lethally irradiated and reconstituted with BALB/c (H-2(d

57 poietic cells, Tie2-Cre/LoxP-PTP1B mice were lethally irradiated and reconstituted with bone marrow f

58 cipate in SGVHD, C3H/HeN recipient mice were lethally irradiated and transplanted with BM from normal

59 ipoprotein E (apoE)(-/-) recipient mice were lethally irradiated and transplanted with COX-1(-/-) bon

60 either Bmpr2(R899X) mutant or controls, were lethally irradiated and transplanted with either control

61 Female mice (6 wk old) were lethally irradiated and transplanted with male bone marr

62 C57/BL6 (H2K(b)) recipient mice were lethally irradiated and underwent cotransplantation with

63 Rats with subtotal nephrectomies were lethally irradiated and underwent salvage transplantatio

64 apacity to achieve long-term repopulation in lethally irradiated animals and the ability to different

65 fetal liver cells also fail to radioprotect lethally irradiated animals and they compete poorly in r

66 al irradiation, and increase the survival of lethally irradiated animals following allogeneic HPC tra

67 ease GVHD mortality in either sublethally or lethally irradiated animals that received graded doses o

68 1(+) cells primed by C3a engrafted faster in lethally irradiated animals.

69 riched with autologous peripheral blood into lethally irradiated animals.

70 Egr1(+/-), Apc(del/+) bone marrow cells into lethally irradiated Apc(del/+) recipients resulted in ra

71 ere used to replace the circulating cells of lethally irradiated ApoE -/- mice.

72 crophage SR-BI were created by transplanting lethally irradiated apoE-deficient mice with bone marrow

73 Lethally irradiated B10.BR mice transplanted with major

74 ritoneal cavity B-1a cells were recovered in lethally irradiated B6.Sle2 mice reconstituted with B6.I

75 R5(-/-) or wild-type C57BL/6 (B6) T cells to lethally irradiated B6D2 recipients.

76 nalyze CD8(+) and CD4(+) T cell responses in lethally irradiated BALB.B and CXB-2 recipients, which s

77 on in skin during development of Scl GVHD in lethally irradiated BALB/c (H-2d) mice transplanted with

78 PD-treated splenocytes were infused into lethally irradiated BALB/c (same-party) or C3H/HeJ (thir

79 All lethally irradiated BALB/c mice inoculated with BCL1 cel

80 Acute GVHD was induced in lethally irradiated BALB/c mice.

81 Lethally irradiated BALB/c/nu/nu mice were injected intr

82 nting B10.D2 bone marrow and spleen cells to lethally irradiated BALB/cJ mice, is a model for human s

83 nd diminished multilineage reconstitution in lethally irradiated bone marrow recipients.

84 Lethally irradiated C3FeB6F(1) hosts received BMT from e

85 of acute graft-versus-host disease (GVHD) in lethally irradiated C57BL/6 (H-2b) recipient mice transp

86 ow cells from lpr mice (which lack Fas) into lethally irradiated C57BL/6 mice (MyFas(-) group) or vic

87 Lethally irradiated C57BL/6 mice were transplanted with

88 e marrow (BM)-chimeric mice by transplanting lethally irradiated C57BL/6 mice with congenic VDR or wi

89 transduced SP cells successfully repopulated lethally irradiated C57BL/6 mice, animals where there is

90 populated multiple hematopoietic lineages of lethally irradiated C57BL/6-CD45.2 mice.

91 transplanted viable clones individually into lethally irradiated C57BL/6-Ly-5.1 mice.

92 Lethally irradiated C57BL/6J and B6.129P2-Nos2(tm1Lau)/J

93 owing syngeneic bone marrow transplants into lethally irradiated C57BL6 mice, MAPCs are of donor orig

94 Lethally irradiated CBA mice received BMT from allogenei

95 etermine LC lineage origin, we reconstituted lethally irradiated CD45.2 mice with rigorously purified

96 We immunized mice i.p. with lethally irradiated cells of the colon adenocarcinoma li

97 ons derived from these candidate HSCs into a lethally irradiated congenic non-EGFP mouse.

98 ls received heart and kidney allografts from lethally irradiated donors (n=7); group 5 animals receiv

99 genitors per tibia of WT HSPCs injected into lethally irradiated Fancg(-/-) recipients.

100 tion of macrophage LRP(-/-) bone marrow into lethally irradiated female LDLR(-/-) recipient mice resu

101 Lethally irradiated female mice were rescued by a BM tra

102 galactosyltransferase and transplanted into lethally irradiated gal knockout mice.

103 s, alone or mixed with wild-type cells, into lethally irradiated healthy mice.

104 -cell resolution, whereby the bone marrow of lethally irradiated host animals is reconstituted with E

105 atopoiesis and allowed long-term survival of lethally irradiated host animals.

106 impaired in their capacity to reconstitute a lethally irradiated host.

107 lantation of Bv8 null fetal liver cells into lethally irradiated hosts also reduced metastasis.

108 er, Ripk1(-/-) progenitors failed to engraft lethally irradiated hosts properly.

109 Reciprocal bone marrow transfers into lethally irradiated hosts suggested that defects in both

110 lls and adoptive transfer of thymocytes into lethally irradiated hosts suggested that recent thymic e

111 (HSCs) lacking SOD2 are capable of rescuing lethally irradiated hosts, but reconstituted animals dis

112 When transferred into lethally irradiated hosts, E2A-deficient hematopoietic p

113 ng bone marrow reconstitution experiments of lethally irradiated hosts, we have defined the extent an

114 expansion, as a single HSC may reconstitute lethally irradiated hosts.

115 with fluorescent PKH26 dye and injected into lethally irradiated hosts.

116 splanted cNeoblasts restored regeneration in lethally irradiated hosts.

117 n sublethally irradiated immunodeficient and lethally irradiated immunocompetent mice.

118 mory anti-Gal B cells were administered into lethally irradiated KO mice, together with syngeneic wil

119 ow-derived murine DC were exposed to various lethally irradiated Lactobacillus spp. and resultant cul

120 To confine MPO expression to macrophages, we lethally irradiated LDL receptor-deficient mice and repo

121 row transplantation experiments performed in lethally irradiated LDL-R null female mice, reconstitute

122 /-) or wild-type mice were transplanted into lethally irradiated Ldlr(-/-) mice.

123 om littermate controls was transplanted into lethally irradiated low density lipoprotein receptor Ldl

124 either FucT-VII(-/-)GFP(+) bone marrow into lethally irradiated low-density lipoprotein receptor low

125 mice die by 3 weeks of age, this study used lethally irradiated low-density lipoprotein receptor-def

126 population for long-term engrafting cells in lethally irradiated Ly-5.2 mice.

127 kyrin-1 promoter vectors, were injected into lethally irradiated Ly5.2 recipients.

128 icient lymphocytes by adoptive transfer into lethally irradiated mature lymphocyte-deficient recombin

129 own that bone marrow cells transplanted into lethally irradiated mdx mice, the mouse model of DMD, ca

130 ismatched T cell-deficient C57BL/6 mice into lethally irradiated MHC-matched B6.H-2(g7) recipients, w

131 /+).BDC2.5 or NOD.Rag1(-/-).BDC2.5 mice into lethally irradiated MHC-mismatched H-2(b) C57BL/6 or MHC

132 ther intra bone marrow or intravenously into lethally irradiated MHC-mismatched recipient mice.

133 fect of DDT-deficient HSCs in reconstituting lethally irradiated mice and a strong competitive disadv

134 engraftment and enhanced overall survival in lethally irradiated mice by mitigating damage to the BM

135 ells and stromal cells, is transplanted into lethally irradiated mice deleted of both the p55 and p75

136 t the mouse homologue, murine CMV (MCMV), in lethally irradiated mice given allogeneic purified hemat

137 juvenile myelomonocytic leukemia (JMML) and lethally irradiated mice given transplants with homozygo

138 In lethally irradiated mice injected with donor congenic bo

139 inhibits graft-versus-host disease (GVHD) in lethally irradiated mice receiving allogeneic hematopoie

140 Finally, the hematopoietic reconstitution of lethally irradiated mice receiving transplanted BM monon

141 In lethally irradiated mice reconstituted with bone marrow

142 is associated with cachexia and mortality in lethally irradiated mice reconstituted with dominant neg

143 Lethally irradiated mice reconstituted with Gnai2(-/-) b

144 on of RIP to immune homeostasis, we examined lethally irradiated mice reconstituted with rip-/- hemat

145 Since lethally irradiated mice reconstituted with SYK-deficien

146 ietic stem cells mobilized by SB-251353 into lethally irradiated mice resulted in faster neutrophil a

147 of 5,000 lentivirus-transduced SP cells into lethally irradiated mice resulted in long-term expressio

148 e other hand, transfer of WT BM into BAFF-/- lethally irradiated mice resulted only in minimal recons

149 eted whole bone marrow or purified HSCs into lethally irradiated mice results in a profound engraftme

150 murine BM cells covered with PMPs engrafted lethally irradiated mice significantly faster than those

151 e so-called side population (SP) cells, into lethally irradiated mice subsequently rendered ischemic

152 Here, we show that in lethally irradiated mice that had received BM transplant

153 bited microcytic, hypochromic anemia, as did lethally irradiated mice that received a transplant of S

154 unctional natural killer (NK) compartment in lethally irradiated mice that received bone marrow cells

155 is lentiviral vector design was evaluated in lethally irradiated mice that received transplants of tr

156 fer following long-term transplantation into lethally irradiated mice transgenic for HLA-DR4.

157 Lethally irradiated mice transplanted with 2 x 10(6) FL,

158 Lethally irradiated mice transplanted with bone marrow c

159 Here, all lethally irradiated mice transplanted with Dnmt3a-delete

160 del of soft tissue ischemia was developed in lethally irradiated mice with BM reconstituted from eith

161 Dll4, in mice was explored by reconstituting lethally irradiated mice with bone marrow (BM) cells tra

162 P-selectin(-/-) and apoE(-/-)P-selectin(+/+) lethally irradiated mice with bone marrow of either geno

163 ouse model of JMML through reconstitution of lethally irradiated mice with hematopoietic stem cells h

164 em that are radioprotective, we transplanted lethally irradiated mice with purified progenitors: comm

165 capacity to reject bone marrow allografts in lethally irradiated mice without prior sensitization.

166 d to express RUNX1-ETO and transplanted into lethally irradiated mice, and a high penetrance of AML w

167 ulate all major peripheral blood lineages in lethally irradiated mice, but the origin of this activit

168 from protecting hematopoietic progenitors in lethally irradiated mice, indicating involvement of a fa

169 r:bone marrow cell mixtures were placed into lethally irradiated mice, only treatment of these mixtur

170 When transplanted into lethally irradiated mice, single gene-marked murine SP c

171 When these cells are injected into lethally irradiated mice, they engraft transiently in a

172 me near nestin(+) MSCs in the bone marrow of lethally irradiated mice, whereas in vivo nestin(+) cell

173 econstitution of the hematopoietic system in lethally irradiated mice.

174 on of bone marrow and are able to repopulate lethally irradiated mice.

175 tilineage reconstitution when transferred to lethally irradiated mice.

176 oietic progenitor cells used to reconstitute lethally irradiated mice.

177 cell lympholeukemias when transplanted into lethally irradiated mice.

178 of donor hematopoietic cells to radioprotect lethally irradiated mice.

179 to reconstitute the hematopoietic system of lethally irradiated mice.

180 ncompatible bone marrow cell (BMC) grafts in lethally irradiated mice.

181 did not expand as did their counterparts in lethally irradiated mice.

182 of hematopoietic progenitors in vitro and in lethally irradiated mice.

183 d-type (wt) fetal liver (FL) stem cells into lethally irradiated mice.

184 dye and can reconstitute the bone marrow of lethally irradiated mice.

185 obilized peripheral blood stem cells rescued lethally irradiated mice.

186 ow and spleen, and thereby prevent death, in lethally irradiated mice.

187 e capable of hematopoietic reconstitution of lethally irradiated mice.

188 s capable of hematopoietic reconstitution of lethally irradiated mice.

189 fractions by flow sorting, and injected into lethally irradiated mice.

190 duced the number of HSPCs required to rescue lethally irradiated mice.

191 uted multilineage long-term hematopoiesis in lethally irradiated mice.

192 c stem/progenitor cells used to reconstitute lethally irradiated mice.

193 to reconstitute the hematopoietic system of lethally irradiated mice.

194 HSCs from ossicles were able to reconstitute lethally irradiated mice.

195 marrow, but not wild-type bone marrow, into lethally irradiated MMTV-PyVmT mice (a model of metastat

196 ed self-renewal in serial transplantation of lethally irradiated mouse recipients both in the presenc

197 8 h and tested for engraftment capacity in a lethally irradiated murine competitive transplant model.

198 ice (BALB/c and C3H/HEJ) were immunized with lethally irradiated murine leukemia cells expressing cel

199 istocompatibility complex class I-mismatched lethally irradiated murine model.

200 ized that flagellin could ameliorate GVHD in lethally irradiated murine models of allogeneic HSCT.

201 We used a lethally irradiated murine SCT model (B6 --> bm1) to eva

202 en fluorescent protein (GFP)-marked HSC into lethally irradiated nontransgenic recipients.

203 In lethally irradiated normal mice that were reconstituted

204 bone marrow chimeras made by reconstituting lethally irradiated normal mice with bone marrow taken f

205 prevent graft-versus-host disease (GVHD) in lethally irradiated or nonirradiated allogeneic recipien

206 ined populations of BM cells were tracked in lethally irradiated or nonirradiated mice at 1, 3, 6, an

207 The wild-type mouse was either uninjured or lethally irradiated or received intratracheal elastase o

208 o test this hypothesis, IPS was induced in a lethally irradiated parent --> F1 mouse BMT model.

209 Using a lethally irradiated parent --> F1 mouse IPS model, we sh

210 acute graft-versus-host disease (GVHD) in a lethally irradiated parent into F1 (B6-->B6D2F1) BMT mod

211 epopulating lymphoid and myeloid lineages of lethally irradiated primary and secondary hosts, with de

212 in tertiary hosts and could not radioprotect lethally irradiated quaternary recipients.

213 ferent viruses were transplanted into either lethally irradiated Rag-1-deficient animals or Artemis k

214 actively transcribed were transplanted into lethally irradiated recipient female mice.

215 Serial BM transplantation into lethally irradiated recipient mice indicated an essentia

216 Limiting dilution reconstitution of lethally irradiated recipient mice with 100% transduced,

217 f myeloproliferative neoplasms, we engrafted lethally irradiated recipient mice with bone marrow cell

218 ed by reconstitution of the immune system of lethally irradiated recipient mice with retrovirus-infec

219 rostinil and forskolin, enhanced survival of lethally irradiated recipient mice.

220 ted HSPCs to reconstitute the bone marrow in lethally irradiated recipient mice.

221 d higher repopulation capacity and protected lethally irradiated recipient mice.

222 performed bone marrow transplantations into lethally irradiated recipient mice.

223 Rce1(-/-) fetal liver cells rescued lethally irradiated recipients and manifested normal lon

224 d Shp2-deficient HSCs failed to reconstitute lethally irradiated recipients because of defects in hom

225 ed from adult bone marrow and transferred to lethally irradiated recipients clearly give rise to B-2,

226 m congenic controls and used to reconstitute lethally irradiated recipients for analysis of long-term

227 MDSCs transferred to lethally irradiated recipients of allogeneic donor hemat

228 tation of 500 HSCs from old p53+/m mice into lethally irradiated recipients resulted in reduced engra

229 The i.v. injection of HoxB8 progenitors into lethally irradiated recipients resulted in the appearanc

230 ntation of transduced bone marrow cells into lethally irradiated recipients showed that the percentag

231 Lethally irradiated recipients were reconstituted with p

232 uted the bone marrow and peripheral blood of lethally irradiated recipients with B lineage cells with

233 toxic injury, and HO-1(+/-) HSCs repopulated lethally irradiated recipients with more rapid kinetics.

234 cell phenotype, provided radioprotection to lethally irradiated recipients, and enhanced in vivo rep

235 of CD31+ Lin- c-kit- cells fails to protect lethally irradiated recipients, while CD31+ Lin- c-kit+

236 cells provides short-term radioprotection of lethally irradiated recipients, whose progressive anemia

237 00-deficient HSC were unable to reconstitute lethally irradiated recipients.

238 ely reconstitute the hematopoietic system of lethally irradiated recipients.

239 for survival following transplantation into lethally irradiated recipients.

240 m H2 identical healthy mice could not rescue lethally irradiated recipients.

241 nitored tumor onset and overall pathology in lethally irradiated recipients.

242 ion assays, 100 such cells reconstituted all lethally irradiated recipients.

243 splantation of mutant fetal liver cells into lethally irradiated recipients.

244 ls alone could not produce reconstitution in lethally irradiated recipients.

245 ells failed to reconstitute hematopoiesis in lethally irradiated recipients.

246 nsplanted necdin-null fetal liver cells into lethally irradiated recipients.

247 B502 also showed radioprotective activity in lethally irradiated rhesus monkeys.

248 In the current study, we used lethally irradiated S. aureus as a model multicomponent

249 tly extended lifespan, increased survival of lethally irradiated secondary recipients transplanted wi

250 sick mice along with B6 bone marrow cells to lethally irradiated syngeneic B6 mice, the secondary rec

251 y of infection of 100, and transplanted into lethally irradiated syngeneic mice.

252 e marrow coexpressing TEL-PDGFRB and AE into lethally irradiated syngeneic mice.

253 either Jak2 wild-type (wt) or Jak2V617F into lethally irradiated syngeneic recipient mice.

254 Reconstitution of lethally irradiated syngeneic recipients with BM transdu

255 Instead, lethally irradiated tapeworms can be rescued when cells

256 on, we transplanted normal marrow cells into lethally irradiated Tpo(-/-) and Tpo(+/+) mice and quant

257 een fluorescent protein-expressing mice into lethally irradiated transgenic mice followed by subseque

258 bone marrow cells were transplanted into two lethally irradiated transgenic mouse models of HD that u

259 t introduction of wild-type (WT) marrow into lethally irradiated TSP2 KO mice did not rescue the blee

260 d 65.0% fewer inflammatory cells (P<0.05) in lethally irradiated wild type mice reconstituted with CX

261 ese mechanisms, the hematopoietic systems of lethally irradiated wild-type (WT) mice were reconstitut

262 tor GRko for immunological reconstitution of lethally irradiated wild-type (WT) mice.

263 er combined HSC and MPC transplantation into lethally irradiated wild-type (WT) mice.

264 ntation of KLF4(-/-) fetal livers cells into lethally irradiated wild-type mice completely lacked cir

265 Surprisingly, lethally irradiated wild-type mice reconstituted with CX

266 ation of recombinant, soluble Thbd or aPC to lethally irradiated wild-type mice resulted in an accele

267 selectin-dependent rolling, we reconstituted lethally irradiated wild-type mice with PSGL-1-/- bone m

268 8(-/-) unfractionated bone marrow cells into lethally irradiated wild-type mice, resulting in approxi

269 ration, as BAFF-/- BM cells transferred into lethally irradiated WT mice gave rise to normal numbers

270 Lethally irradiated WT mice reconstituted with a 50:50 m

271 red bone marrow cells from Id cDKO mice into lethally irradiated WT mice.

272 that expressed the neutrophil marker Gr-1 in lethally irradiated WT or Rac2(-/-) recipients of Rac2(-

273 leukocytes when adoptively transferred into lethally irradiated WT recipients.

274 KO bone marrow cells failed to radioprotect lethally irradiated WT recipients.

275 Vaccination with lethally irradiated, AdsGRP94-infected 4T1 cells complet

276 IL-6 transgenic knockout mice were lethally irradiated, and their bone marrow was reconstit

277 Adult C57BL/6J mice were lethally irradiated, and then received a transplant of p

278 Lethally irradiated, atherosclerosis-prone, low-density

279 rom apolipoprotein e-/- x stat1-/- mice into lethally irradiated, atherosclerosis-susceptible apolipo

280 Vaccination with lethally irradiated, autologous tumor cells engineered t

281 yte-associated antigen 4 or vaccination with lethally irradiated, autologous tumor cells engineered t

282 Lethally irradiated, established mixed BALB/c--> B6 chim

283 Lethally irradiated, male WASP- animals that received tr

284 BM) cells resulted in bioluminescent foci in lethally irradiated, syngeneic recipients.

285 ecipients deficient in IL-6 (IL-6(-/-)) were lethally irradiated, then rescued with 10(7) donor bone

286 fic protein surfactant protein C (Sp-C) were lethally irradiated, transplanted with sex mismatched wi

287 Lethally irradiated, virus-infected cells were used as v

288 were generated after the recipient mice were lethally irradiated.

289 We found that lethally- irradiated lymphocyte-deficient C57BL/6 (B6).g

290 ) cells that engrafted primary and secondary lethally-irradiated mice, and human CD34(+) cells that c

291 re-engineered to attack, kill, but also non-lethally manipulate the physiologies of bacteria.

292 sential components of the immune system that lethally mutate viral pathogens and somatically mutate i

293 whereas its close relative, APOBEC3G (A3G), lethally mutates the genomes of retroviral pathogens suc

294 iated genome regions that were on their own "lethally recombinant." Surprisingly, mixed inoculations

295 hese data demonstrate the feasibility of non-lethally sampling proteins from cells, greatly extending

296 n of scaRNA to repress transcription without lethally targeting the chromosome.

297 nto a layer of a larger number of unlabeled, lethally treated melanoma cells.

298 In lethally treated mice, Cas-1 activity remained elevated

299 nd adult males and females were not affected lethally until pCO2 concentrations >/=3000 muatm.

300 s are best accounted for by a combination of lethally warm, shallow waters and anoxic deep waters tha