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1 atibility complex (MHC) class I genes (human leukocyte antigen A [HLA-A], -B, and -C genes) may affec
5 tudies have revealed associations with human leukocyte antigen and non-human leukocyte antigen genes
6 tion between HIV genetic variation and human leukocyte antigen and the other studying host range dist
7 art technology employed to assess anti-human leukocyte antigen antibodies (Anti-HLA Ab) for donor-rec
8 de novo detection of circulating anti-human leukocyte antigen antibodies, and clinically significant
9 e, human leukocyte antigen mismatches, human leukocyte antigen antibodies, cold ischemia time, living
10 caid Services to evaluate whether anti-human leukocyte antigen antibodies, measured as panel reactive
12 th HIV/Mtb had decreased expression of human leukocyte antigen antigen D related and the costimulator
15 eripheral blood mononuclear cells, and human leukocyte antigen-antigen D related expression on circul
17 -cell infiltrates and a strong genetic human leukocyte antigen association represent characteristic f
20 ng the highly sensitive single-antigen human leukocyte antigen bead assay 5.1 +/- 3.9 months after th
21 rategy relies on initial prediction of human leukocyte antigen-binding peptides by in silico algorith
22 owever, we identified in one patient a human leukocyte antigen-C*08:02-restricted T cell receptor fro
24 nts, we observed reduced expression of human leukocyte antigen class DR (HLA-DR) and proinflammatory
26 years, adjusted P = 0.010) and several human leukocyte antigen class I (HLA-I) alleles, including HLA
27 al diversity of the highly polymorphic human leukocyte antigen class I (HLA-I) genes underlies succes
31 ng placental trophoblast cells express human leukocyte antigen class I ligands (HLA-E, HLA-G, and HLA
32 lysis of immune responses ex vivo used human leukocyte antigen class I pentamers, intracellular cytok
33 cytometry with ultrasensitive peptide-human leukocyte antigen class I tetramer staining to quantify
35 and c-Met and the immunologic markers human leukocyte antigen class II and programmed death ligand 1
37 the antigens that will be presented by human leukocyte antigen class II molecules (HLA-II), hindering
38 em through their interactions with the human leukocyte antigen complex, and neoantigen presence has r
40 xt of human leukocyte antigen (peptide-human leukocyte antigen complex; pHLA) molecules on tumor cell
42 of circulating activated CD4+ T cells (human leukocyte antigen-D related [HLA-DR]+CD38+CD4+) (from 3.
43 monocytes expressed reduced levels of human leukocyte antigen-D-related peptide and released less so
45 ompared to non-PSC controls, including human leukocyte antigen DM alpha chain and chemokine (C-C moti
48 dyslipidemia (P=0.009), class II anti-human leukocyte antigen donor-specific antibodies (P=0.004), a
49 ompatibility complex class II (MHC-II) human leukocyte antigen DR isotype (HLA-DR) is an essential en
51 evels of macrophage-derived chemokine, human leukocyte antigen DR, CD80, and CD86 were increased in a
52 egulated macrophage-derived chemokine, human leukocyte antigen DR, CD86, and CD80 correlated positive
53 atory T-cell frequency, activated CD38+Human Leukocyte Antigen - DR isotype (HLA-DR)+ CD4 and CD8 T c
54 showed increased circulating activated human leukocyte antigen, DR isotype ([HLA-DR] positive) CD8(+)
55 ultured in perioperative serum and CD14Human Leukocyte Antigen-DR (HLA-DR) [monocyte HLA-DR (mHLA-DR)
56 he ocular surface inflammatory markers human leukocyte antigen-DR (HLA-DR) and intercellular adhesion
57 both demonstrated increased levels of human leukocyte antigen-DR (HLA-DR) following IFN-gamma stimul
58 oses, an apparent increase in monocyte human leukocyte antigen-DR expression (> 5,000 monoclonal anti
59 septic shock patients stratified using human leukocyte antigen-DR expression on monocytes (mHLA-DR).
60 gadolinium 160 ((160)Gd)-labeled anti-human leukocyte antigen-DR isotope (HLA-DR) antibodies to dete
65 zed in SARS-CoV- and MERS-CoV-infected human leukocyte antigen DR2 and DR3 transgenic mice, indicatin
67 id, which suppresses the expression of human leukocyte antigen E (HLA-E) in cancer cells, thus activa
68 lity complex (MHC), a mouse homolog of human leukocyte antigen-E (HLA-E), inhibits antibody-mediated
70 sidedness dependent differential hMSC human leukocyte antigen expression, angiogenic and inflammator
72 tibility complex (MHC) molecule HLA-F (human leukocyte antigen F) regulates the immune system in preg
77 mber of the KIR family that recognizes human leukocyte antigen G and mediates NK-cell activation thro
79 differentiation preferentially toward human leukocyte antigen-G(+) pcEVT, and that an intact HIF com
80 eptor(+) villous cytotrophoblasts into human leukocyte antigen-G(+) proximal column EVT (pcEVT) and i
82 kin-10 gene (IL10) T3575A), rs6457327 (human leukocyte antigen gene (HLA) class I), rs10484561 (HLA c
83 r, the functional relationship between human leukocyte antigen gene(s) and disease development remain
84 ts associated with DHRs are located in human leukocyte antigen genes and genes involved in drug metab
86 s with human leukocyte antigen and non-human leukocyte antigen genes of 3 major histocompatibility co
87 zed for disease-associated variants in human leukocyte antigen genes; results must be carefully inter
88 he child after adjustment for country, human leukocyte antigen genotype, family history of celiac dis
89 raves' disease controls), using direct human leukocyte antigen genotyping and SNP-based genome-wide a
90 resent review describes the biology of human leukocyte antigen haplotype mismatched ("haploidentical"
93 L (ALY) is presented in the context of human leukocyte antigen HLA-A*02:01 molecules for recognition
96 nalyzed humoral immune responses to nonhuman leukocyte antigen (HLA) after cardiac transplantation to
98 MHC (chr6: 29.6-33.1 Mb), imputing 216 human leukocyte antigen (HLA) alleles and 4 complement compone
99 ies new associations between classical human leukocyte antigen (HLA) alleles and common immune-mediat
100 searched for genetic associations with human leukocyte antigen (HLA) alleles and IFN-lambda3 gene (IF
102 e detected the involvement of the same human leukocyte antigen (HLA) alleles in both SCZ and MS, but
103 de Polymorphisms (SNPs) and 38 imputed Human Leukocyte Antigen (HLA) alleles were analyzed through a
104 ct of source partner HIV-1 RNA levels, human leukocyte antigen (HLA) alleles, and innate responses th
105 wide association study (GWAS), imputed human leukocyte antigen (HLA) alleles, exome array and copy-nu
109 edically important regions such as the human leukocyte antigen (HLA) and killer cell immunoglobulin-l
112 idney recipients monitored for de novo human leukocyte antigen (HLA) antibody (Ab) occurrence to gain
113 d single allele cells to identify anti-human leukocyte antigen (HLA) antibody cross-species reactivit
115 these cohorts to further fine map the human leukocyte antigen (HLA) association and replicated our r
116 )) and confirm the previously reported human leukocyte antigen (HLA) associations on chromosome 6p21
117 fied by several key examples and their human leukocyte antigen (HLA) associations: abacavir and HLA-B
118 ecurrence was higher for patients with human leukocyte antigen (HLA) B49 (odds ratio, 16.9; 95% confi
119 Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable of mediat
123 While the relationship of protective human leukocyte antigen (HLA) class I alleles and HIV progress
124 the Middle East, sequenced HDV, typed human leukocyte antigen (HLA) class I alleles from patients, a
128 ts with chronic HBV infection, and the human leukocyte antigen (HLA) class I genotype (A and B loci)
130 lone's ability to downregulate CD4 and human leukocyte antigen (HLA) class I in vitro We then explore
132 or Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) Class I molecules bind to peptid
136 me generates the epitopes presented on human leukocyte antigen (HLA) class I molecules that elicit CD
137 wo broad strategies for recognition of human leukocyte antigen (HLA) class I molecules: (i) direct re
138 ct the link between hyperexpression of human leukocyte antigen (HLA) class I on the islet cells, we e
141 ells, thus enabling their evasion from human leukocyte antigen (HLA) class I-restricted CD8(+) T-cell
142 c context influences HIV adaptation to human leukocyte antigen (HLA) class I-restricted immune pressu
143 e that allow it to escape detection by human leukocyte antigen (HLA) class I-restricted immune respon
144 ity and revealed previously undetected human leukocyte antigen (HLA) class I-restricted neoantigens i
146 eases pathogen resistance is linked to human leukocyte antigen (HLA) class I/II variants and their in
147 rexin), is so strongly associated with human leukocyte antigen (HLA) class II HLA-DQA1( *)01:02-DQB1(
148 ze peptide antigens, in the context of human leukocyte antigen (HLA) class II molecules (HLA-II), whi
149 prediction of antigen presentation by human leukocyte antigen (HLA) class II molecules would be valu
150 Here, we demonstrate the presence of human leukocyte antigen (HLA) class II-restricted CD8(+) T cel
152 signal in the class III region of the human leukocyte antigen (HLA) complex in the South Asian datas
154 ein that are likely to be presented in human leukocyte antigen (HLA) complexes, and discuss the role
155 ransplant antibodies directed at donor human leukocyte antigen (HLA) donor-specific antibodies (DSA)
163 equencing (NGS)-based typing of the 33 human leukocyte antigen (HLA) genes in 1,120 individuals of Ja
164 uencing studies have demonstrated that human leukocyte antigen (HLA) genes may be expressed in a cell
165 ymorphic genetic system in humans, the human leukocyte antigen (HLA) genes of the adaptive immune sys
166 ller immunoglobulin-like receptors and human leukocyte antigen (HLA) genotype with risk of CMV diseas
168 ght association of narcolepsy with the human leukocyte antigen (HLA) HLA-DQB1*06:02 allele, we first
169 DSA) directed against mismatched donor human leukocyte antigen (HLA) is a major risk factor for graft
171 this locus, we imputed alleles at classical leukocyte antigen (HLA) loci using HLA*IMP:02 with a ref
173 However, loss of heterozygosity at the human leukocyte antigen (HLA) locus and loss of chromosome 8p
175 eral reports linked the disease to the human leukocyte antigen (HLA) locus on chromosome 6, followed
177 ability to present neoantigens through human leukocyte antigen (HLA) loss may facilitate immune evasi
179 Then, three decades ago, an unusual human leukocyte antigen (HLA) molecule was identified: HLA-G.
180 on the cell surface in the context of human leukocyte antigen (HLA) molecules have been targeted by
181 tors (KIRs) with their target ligands, human leukocyte antigen (HLA) molecules, is a critical compone
182 ct ASI to patients expressing specific Human Leukocyte Antigen (HLA) molecules, thus stratifying the
185 inding preferences of the best-matched Human Leukocyte Antigen (HLA) pocket for each SLA pocket.
186 increases the presentation of class I human leukocyte antigen (HLA) proteins that limit antiviral re
187 host, and is linked to their allele of human leukocyte antigen (HLA) proteins, which present protein
188 These include transcripts encoding human leukocyte antigen (HLA) receptors as well as B cell and
192 n favoring sub-Saharan ancestry at the human leukocyte antigen (HLA) region, across North African ind
193 ancer associations were limited to the human leukocyte antigen (HLA) region, and classical HLA allele
194 tability of IQ might lie hidden in the human leukocyte antigen (HLA) region, which plays a critical r
203 high sequence divergence harboring the human leukocyte antigen (HLA) system, we found that local real
205 purpose of this study was to identify human leukocyte antigen (HLA) type as risk and prognostic fact
206 ements a new graph alignment model for human leukocyte antigen (HLA) type inference, based on the pro
208 kflow Language (CWL) implementation of human leukocyte antigen (HLA) typing using Polysolver or HLAmi
209 in vitro model of ABMR due to class I human leukocyte antigen (HLA) with and without complement acti
210 e peptides associated with the class I human leukocyte antigen (HLA), of which 98 peptides were deriv
211 Aggregate morphologies also influence Human Leukocyte Antigen (HLA)--types recognized by the aggrega
212 tients with glioblastomas positive for human leukocyte antigen (HLA)-A*02:01 or HLA-A*24:02 were trea
213 after immune-affinity purification of human leukocyte antigen (HLA)-A2 and bioinformatics to identif
214 e CD8(+) T cells in situ, in islets of human leukocyte antigen (HLA)-A2(+) donors and isolation and i
215 of genes encoding human cytokines and human leukocyte antigen (HLA)-A2.1 by adeno-associated virus s
217 ariation of the two minimally distinct human leukocyte antigen (HLA)-B*27:05 and HLA-B*27:09 subtypes
219 Consecutive patients with AU who were human leukocyte antigen (HLA)-B27 positive or HLA-B27 negative
222 udies suggest that the presence of the human leukocyte antigen (HLA)-Cw6 (C*06:02) allele may be a pr
225 nd associations of narcolepsy with the human leukocyte antigen (HLA)-DQ6 allele and T-cell receptor a
226 eased expression of maturation markers human leukocyte antigen (HLA)-DR and CD86, enhanced tumor necr
227 d T-cell epitopes presented in vivo by human leukocyte antigen (HLA)-DR molecules in patients' inflam
228 ozygosity for the previously validated human leukocyte antigen (HLA)-DR*03:01 risk allele predicted i
232 estricted by the human MHC-Ib molecule human leukocyte antigen (HLA)-E and specific for an epitope fr
237 inuclear antibodies (ANA), presence of human leukocyte antigen (HLA-)B27, age of onset of JIA, and se
238 gD, VP11/12, and VP13/14 proteins, in human leukocyte antigen (HLA-A*0201) transgenic rabbits infect
239 tributed to the genes encoding class I human leukocyte antigens (HLA) and the chemokine receptor CCR5
240 eterminants that underlie targeting of human leukocyte antigens (HLA) by anti-HLA alloantibodies is p
241 leles, genes or haplotypes) related to human leukocyte antigens (HLA), killer-cell immunoglobulin-lik
242 eveloped for other complex loci (e.g., human leukocyte antigen [HLA]) on the basis of SNP data provid
243 ed and mobilized within immunodominant human-leukocyte-antigen-(HLA)-A*11:01-restricted CD8(+) T cell
244 Understanding the binding between human leukocyte antigens (HLAs) and peptides is important to u
246 evasion of innate immunity.IMPORTANCE Human leukocyte antigens (HLAs) are cell surface proteins that
249 harboring genes encoding the class II human leukocyte antigens (HLAs): rs557011[T] (minor allele fre
252 on a safe conversion to belatacept in human leukocyte antigen-immunized patients with low DSA levels
253 nversion from CNIs to belatacept in 29 human leukocyte antigen-immunized renal-transplant recipients.
254 SCCHN risk highlight the importance of human leukocyte antigen loci for oropharyngeal cancer risk, su
257 iations to genetic variants, including human leukocyte antigen loci with carbamazepine-induced dermat
261 , we present loss of heterozygosity in human leukocyte antigen (LOHHLA), a computational tool to dete
262 efined pre-transplant characteristics: human leukocyte antigen match (10/10 versus <10/10) and diseas
263 the recipient (younger donor or better human leukocyte antigen match), whereas delays beyond 3 months
265 ere compared to CD4(+) responses in 10 human leukocyte antigen-matched persons with HCV spontaneous r
266 rted the first successful histocompatibility leukocyte antigen-matched sibling donor bone marrow and
267 n of hematopoietic stem cells from his human leukocyte antigen-matched sister 1 year prior to admissi
268 n of hematopoietic stem cells from his human leukocyte antigen-matched sister 1 year prior to admissi
269 sly and capable of recognizing cognate human leukocyte antigen-matched tumors are emerging as relevan
271 ty of performing combined histocompatibility leukocyte antigen-matched, sibling donor bone marrow and
273 r T-cell-mediated rejection and BKVAN, human leukocyte antigen mismatch, cyclosporine therapy, and in
275 o mixed lymphocyte co-cultures between human leukocyte antigen-mismatched peripheral blood lymphocyte
276 basiliximab induction, sex, donor age, human leukocyte antigen mismatches, human leukocyte antigen an
277 ow that both alleles of genes encoding human leukocyte antigen molecules and genes encoding component
278 with either loss of heterozygosity in human leukocyte antigens or depletion of expressed neoantigens
279 resented as peptides in the context of human leukocyte antigen (peptide-human leukocyte antigen compl
280 receptor (TCR) recognition of peptide-human leukocyte antigen (pHLA) complexes and is essential for
281 sed yeast-display libraries of peptide-human leukocyte antigen (pHLA) to screen for antigens of "orph
282 We tested the selectivity and efficacy of leukocyte antigen, PLAUR (plasminogen activator, urokina
284 ivated C3 localized at synapses within human leukocyte antigen-positive cell processes and lysosomes,
285 olymorphism rs41269979 in the class II human leukocyte antigen region was more frequent in the invasi
286 nalysis to dissect associations in the human leukocyte antigen region, which suggests important roles
287 extracellular diffusible ligands or require leukocyte antigen-related (Lar), a receptor protein tyro
288 d, the receptor protein tyrosine phosphatase leukocyte-antigen-related (LAR), abolished activity rhyt
290 gen receptor, enabling this simple non-human leukocyte antigen-restricted approach to enhanced CAR-T
291 characteristics, the identification of human leukocyte antigen risk alleles, and drug-induced prolife
297 and a highly multiplexed peptide-HLA (human leukocyte antigen) tetramer staining strategy, we probed
299 n tumor antigen NY-ESO-1 (ESO) and the human leukocyte antigen variant HLA-A*0201 (A2) as a model and
300 creates a neoepitope presented by the human leukocyte antigen with the A2 serotype (HLA-A2) that has