ライフサイエンスコーパス: leverage

1 ered to at-risk populations in 25 countries, leveraging $19 billion in donated drugs-approximately $2

2 Here, we leverage a class of known membrane-targeting compounds t

3 Here, we leverage a diffusion MRI technique, restriction spectrum

4 nism-of-action (MOA) modeling, each of which leverage a priori knowledge of molecular subtypes of tum

5 We instantiate and leverage a small constellation of concrete model mechani

6 In this review, the authors leverage a translational framework to bring together fin

7 We next leveraged a mass spectrometry metabolite profiling platf

8 To identify effective PDAC therapies, we leveraged a syngeneic orthotopic PDAC transplant mouse m

9 The diagnostic leverages a T-junction waveguide device to monitor imped

10 Leveraging a collaborative RPPA model, we set out to ass

11 work has shown that machine learning methods leveraging a combination of traditionally collected epid

12 By leveraging a dynamic phase modulation, the proposed line

13 Leveraging a granular atlas of chromatin accessibility a

14 , we report the design of a catalytic system leveraging a remote directing template and a transient n

15 e describe the somatic events underlying BC, leveraging a targeted next-generation sequencing approac

16 Leveraging a whole-brain electron microscopy volume, we

17 n of HIV-1 infection provides a rationale to leverage ADCC-mediating antibodies for treatment purpose

18 ng and stimulated samples can be combined to leverage additional power whilst still allowing differen

19 Elucidation of the role of this intermediate leveraged additional bond-forming chemistry and enabled

20 Here, we develop such a custom annotation by leveraging advanced assays, such as eCLIP, Hi-C, and who

21 We leverage advances in earthquake monitoring with a deep-l

22 Cancer imaging, in particular, has leveraged advances in MI agents and technology to improv

23 Ms in the V and J segments of the BCR can be leveraged along with the junction sequence to improve th

24 To address this limitation, we leverage an in vitro ribosome synthesis platform to buil

25 Leveraging an autochthonous mouse model, we demonstrate

26 This non-trivial performance is achieved by leveraging an optimized dielectric-metal-dielectric stru

27 The model both leverages and extends current leading approaches to this

28 enomic fine-mapping studies, some approaches leverage annotation data to prioritize likely functional

29 termine statistical significance, and it can leverage any black-box multivariate model and additional

30 e, reactivation of divergent pathways can be leveraged as a previously unrecognized strategy to enhan

31 Whether PLK4 inhibitors can be leveraged as a treatment for cancer is not yet clear.

32 The developed platform technology thus leverages aTF evolvability for the development of new ho

33 cinal chemistry programs by more effectively leveraging available data to guide a molecular design.

34 Herein, we leveraged banked samples from patients enrolled in the N

35 nt a new concept for on-chip separation that leverages bidirectional flow, to tune the dispersion reg

36 These rapid responses leverage billions of mobile phones, large online dataset

37 and a Cys-reactive warhead-were designed to leverage both affinity and reactivity.

38 and future transversal approaches needed to leverage both fetal brain and organoid resources promise

39 strate the power of combinatorial approaches leveraging both in vivo models and high-dimensional data

40 ites and that the autophagy mechanism may be leveraged by delta-catenin and other effectors to sculpt

41 -based models outperformed a reference model leveraging canonical individual characteristics by achie

42 By leveraging causal network and upstream regulator analysi

43 We leveraged cell types defined by gene expression to annot

44 However, how to leverage cellular signaling to ablate TMPRSS2-ERG oncopr

45 ic variation as numeric tensors allows us to leverage CNNs for variant filtration.

46 Leveraging collaboration with the state government of Ka

47 and identify cancer subtypes, we propose to leverage common patterns of evolution found in patient c

48 ognitive research and designed an experiment leveraging construal level theory (CLT).

49 interaction detection method (CARPID), which leverages CRISPR-CasRx-based RNA targeting and proximity

50 Both methods leverage cryo-electron tomograms of ternary membranes un

51 This study leveraged data from a previously published article and r

52 Our analysis leveraged data on >4000 leak indications found using AML

53 We reviewed studies that leveraged data-driven approaches to examining heterogene

54 By leveraging data for 13,069 riverine sites from temperate

55 lopment and a wide array of these factors by leveraging data from the IMAGEN study, a longitudinal po

56 Leveraging data on the contextual microbiome, we assess

57 New research powerfully leverages decades of plant collections to uncover global

58 onal filters and a segmentation routine that leverages deep learning and sparse representations to re

59 ng and delivering drugs to tumours typically leverage differentially upregulated surface molecules on

60 ed synthetic platform to complex ophiobolins leveraging disparate termination modes of a radical poly

61 Leveraging diverse recruitment methods, sites enrolled 1

62 Specifically, we leverage droplet magnetofluidics (DM) to automate the mo

63 ional axis and horizontal extraocular muscle leverage during horizontal duction.

64 Tumours leverage ECM remodelling to create a microenvironment th

65 Using this strategy, we leverage electrochemistry to seamlessly combine two cano

66 ernative exons across the nervous system and leverage ENCODE and GTEx data sets to study the unique s

67 By leveraging ENCODE data on chromatin modification, we ide

68 Nonlinear nanophotonics leverages engineered nanostructures to funnel light into

69 ging to guide the design of diagnostics that leverage enzymatic activity to measure or produce biomar

70 an extension of the RNA velocity method that leverages estimates of unprocessed transcript and protei

71 uence information provides an opportunity to leverage evolutionary information to enhance the accurac

72 a machine learning-based tool (PhyteByte) to leverage existing pharmacological data to predict bioact

73 an example, we present a structured process leveraging existing capacity, fisheries officers, that p

74 Such research should leverage experiences from these projects in diverse soci

75 r in detecting functionally relevant loci by leveraging expression quantitative trait loci (eQTLs) fr

76 RIME allows investigators to leverage external validation data to account for measure

77 Our framework shows that leveraging external information to estimate averted infe

78 RNAIndel leverages features derived from indel sequence context a

79 e OligoFISSEQ, a suite of three methods that leverage fluorescence in situ sequencing (FISSEQ) of bar

80 Several vaccine platforms are being leveraged for a rapid emergency response(1).

81 e work wherein the porosity of MOPs has been leveraged for applications related to the storage and se

82 conclude that ABL is a mechanism that can be leveraged for directional VNS.

83 d genetic susceptibility profile that may be leveraged for disease prediction.

84 s provide a multihazard data set that can be leveraged for epidemiological research on tropical cyclo

85 um and natural history museum records can be leveraged for future studies.The copyright holder of the

86 fects to the overall response so they can be leveraged for maximum clinical benefit.

87 thods with reliably stable outputs should be leveraged for prioritizing heat interventions.

88 ctor performance from neural networks can be leveraged for the identification of highly dynamic regio

89 ll expansion following radiation that may be leveraged for the rational design of combinatorial strat

90 xible nanosensor devices, and it may also be leveraged for the stabilization of novel phases and func

91 r metabolic demands in the TME, which can be leveraged for therapeutic benefit.

92 monstrate a library generation workflow that leverages fragmentation and retention time prediction to

93 We first demonstrate that mTADA is able to leverage genetic overlaps to increase the statistical po

94 siderable progress has recently been made by leveraging genetic information.

95 Many recent investigations have leveraged genome-wide association studies (GWAS) to iden

96 Here we leveraged genomic data from one of the last remaining pu

97 Leveraging glycoproteomic analysis via mass spectrometry

98 By leveraging Google and Apple mobility data, we find empir

99 Issues addressed include leveraging harm reduction tools and improving integrated

100 n this sub-group, and opens the path towards leveraging HEAs as functional waste forms for a variety

101 Leveraging high-throughput transcriptomics we identify N

102 gularized SIs offer an effective approach to leverage HTP data that is routinely generated in agricul

103 Here, we leverage human, non-human primate, and mouse single-cell

104 down sequencing experiments were possible by leveraging IM separation, which enabled us to separate a

105 oved machine-learning strategies that better leverage image-based information.

106 Our approach leverages imaging of a panel of fluorescent chemical pro

107 xamined whether seasonality could be used as leverage in creation of effective control strategies.

108 Therefore, such syntactic information is leveraged in an inflexible way, where inaccurate one may

109 This reactivity has been leveraged in the design of mechanism-based enzyme inhibi

110 s potentially high-yield targets that may be leveraged in the future for clinical application.

111 Leveraging increasingly available long-term high-frequen

112 ination in a unified likelihood framework by leveraging individual-specific allele frequencies projec

113 we use a quantile regression forest (QRF) to leverage information from 2773 lakes to predict the chlo

114 sc, an algorithm for scRNA-seq analysis that leverages information across both cells and genes.

115 er, we introduce EB-PRS, a novel method that leverages information for effect sizes across all the ma

116 By leveraging information across multiple cardiac cycles, o

117 tforms for ligand discovery are essential to leverage insights from genomic analyses.

118 Recently, researchers have begun to leverage insights from regenerating and metamorphosing o

119 Leveraging large amounts of clinical observed phenotypes

120 Leveraging large-scale summary statistics for migraine (

121 We leverage Locator's computational efficiency to predict l

122 ually available information is scant, we can leverage logical connections among hypotheses to draw re

123 Leveraging logistic regression-, random forest- and grad

124 We leverage machine learning to demonstrate accurate smartp

125 odern problems in medicine and public health leverage machine-learning methods to predict outcomes ba

126 mated Recommendation Tool (ART), a tool that leverages machine learning and probabilistic modeling te

127 By leveraging measurements from diverse genotypes, MAGGIE u

128 nanomaterials with 3D printing, achieved by leveraging mechanical, electrical, magnetic, optical, or

129 ll as efforts towards predictive models that leverage microbiome genetics.

130 Developing novel therapies by leveraging modern drug discovery strategies including co

131 hanks to the sufficient orthogonality of the leveraged modes and to the presence of the spherical con

132 sed learning and label propagation, that can leverage molecular interaction networks to predict gene

133 ctions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks.

134 n ~ 320,000), while colocalization analyses leveraging multi-omic data from GTEx and TOPMed identify

135 nging from protein engineering attempts that leverage mutual information to the reconstruction of anc

136 we examined mechanisms of Foxp3 function by leveraging naturally occurring genetic variation in wild

137 ble to strategic adjustment and the value in leveraging neurophysiological measurements to quantify t

138 In this study, we leverage new mouse lines, viral tools, and molecular mar

139 fer low power efficiency, motivating designs leveraging nonvolatile resistive random access memory (R

140 0) and Cell Stem Cell (Bhaduri et al., 2020) leverage novel glioblastoma organoid models and single-c

141 social interactions of pathogens, along with leveraging novel sensing and -omics technologies to unde

142 uires a reliable computational protocol that leverages observed distance restraints and/or cyclic sym

143 Stiff insoles increased leverage of the foot upon the ground (p < 0.001), and in

144 ture technology, cost reductions through the leveraging of existing infrastructure, and increased pol

145 Therefore, our objective was to leverage on the Miami-Dade County, Florida immature mosq

146 apable of overcoming biological barriers and leveraging on several synergistic cancer cell killing me

147 Herein, by leveraging on van der Waals coupling and energy level ma

148 Radiotracers that leverage other hallmarks of cancer or specific cell-surf

149 itiates the recommendation, an analysis that leverages our existing systems with AI, and the delivery

150 omolecules into well-defined nanostructures, leveraging pathway complexity of molecular disorder to o

151 A cost-effectiveness model leveraging patient-level data from ODYSSEY OUTCOMES (Eva

152 Leveraging phenolic complexation to optimize starch func

153 Leveraging population differences in patterns of linkage

154 self-contained and operates autonomously by leveraging pressure and motion sensors, analyses the use

155 n situ sequencing (pciSeq), an approach that leverages previous scRNA-seq classification to identify

156 Leveraging promoter-capture HiC data, we find that over

157 Thus, there is interest in leveraging proprotein convertase subtilisin/kexin type 9

158 Leveraging quasi-random geographic variation in media ma

159 saicForecast, a machine-learning method that leverages read-based phasing and read-level features to

160 ilico models to characterize inhibitors, and leveraging real-world data from electronic health record

161 I then leverage recent policy changes to evaluate the effect of

162 In the current study, we leveraged recent technological advances in molecular bio

163 ining Lagrangian and Eulerian viewpoints and leveraging recent advances from machine learning.

164 Leveraging recent advances in deep learning may facilita

165 iption of CenH3-deficient holocentromeres by leveraging recently identified centromere components(6)(

166 iscuss opportunities for faculty of color to leverage related diversity and inclusion work to boost t

167 d with LC risk, overall and by histology, by leveraging resources from five prospective cohorts.

168 We leveraged samples assembled over decades of fieldwork to

169 01, SciPy has become a de facto standard for leveraging scientific algorithms in Python, with over 60

170 er, this work provides a novel mechanism for leveraging sequence-level components in order to regulat

171 d with operando powder X-ray diffraction, we leverage single-crystal X-ray diffraction to identify th

172 Here we leveraged single-cell RNA sequencing in combination with

173 Here, we leveraged single-cell RNA sequencing to profile transcri

174 differences and types of social capital when leveraging social capital for recovery from disasters.

175 roaches have addressed these shortcomings by leveraging sparse distance data gathered using site-dire

176 Leveraging spin-dependent charge transfer in the device,

177 Leveraging statistical-learning, we demonstrate that fun

178 A classifier leveraging stool metatranscriptomes resulted in modest p

179 outputs to encourage findability, and how to leverage structural elements of software to make it easi

180 stead, strategies aiming to capitalize on or leverage such heterogeneity may help uncover neurobiolog

181 R and our method with KVMN can appropriately leverage such information to improve model performance.

182 Although researchers have successfully leveraged TCGA data to build prognostic models, most eff

183 Here, we leverage technical advances to resolve the individual pr

184 Here, we leveraged that scaffold to synthesize alpha-particle-emi

185 create hybrid living/synthetic systems that leverage the advantages of both?

186 Here we leverage the favourable properties of tweezer-trapped al

187 Computational approaches can leverage the growing number of large-scale human genomic

188 ext-generation vaccines that can selectively leverage the humoral immune functions, beyond binding an

189 To leverage the image-processing power inherent in CNNs, we

190 We leverage the inferred patient topic mixtures to classify

191 We leverage the knowledge of well-established cancer driver

192 To address these issues, we herein leverage the presence at birth of two types of locomotor

193 ese data and resources provide a platform to leverage the regenerative abilities of neonatal skin to

194 mixed signals using available references and leverage the remaining signal as a new cell component.

195 Here, we leverage the sea urchin embryo for its well-established

196 zed version of these operations allow one to leverage the solution of some tasks to speed up the solu

197 ts across diverse populations, and will also leverage the statistical power afforded by longitudinal

198 Here, we leverage the US PCORnet platform to develop an AKI predi

199 ndary structure prediction do not explicitly leverage the vast number of proteins whose structure is

200 To explore this hypothesis, we leveraged the Alzheimer's Disease Neuroimaging Initiativ

201 Here, we leveraged the comprehensive variant dataset from the ICG

202 We leveraged the presence of clinical subtypes with each di

203 Here we leveraged the TET-OFF system to conditionally silence Ri

204 Here, we leveraged the unique affinity of streptavidin to develop

205 Since LINbase leverages the concept of Life Identification Numbers (LI

206 Our approach leverages the fact that at early stages, tumors recruit

207 Overall, this work leverages the genetic diversity of multiple human cell l

208 ContamLD leverages the idea that contaminants should have haploty

209 In sum, this work leverages the increasingly large number of DAP motif and

210 s based on lateral mobility of receptors and leverages the inherent allostery of GPCR-effector coupli

211 ion and melting curve analysis (AMCA), which leverages the kinetic information in real-time amplifica

212 Our approach leverages the known equivalence between the driving forc

213 It leverages the recruitment of DNA repair factors to doubl

214 The APPS leverages the rotational geometry of the prostate and hi

215 material-assisted sequestration of adenosine leverages the transient surge of extracellular adenosine

216 lection of ECF sigmas and their promoters by leveraging the autoregulatory nature of ECF sigmas as a

217 By leveraging the Brain Imaging Data Structure to standardi

218 llaborative mixed model (TisCoMM) for TWASs, leveraging the co-regulation of genetic variations acros

219 physics can be studied in simple systems by leveraging the concept of multiple simultaneous syntheti

220 By leveraging the conjugation platform, we successfully eng

221 pair of samples and their mutual relatives, leveraging the fact that sharing rates among these indiv

222 immunotherapies has highlighted the power of leveraging the immune system in the fight against cancer

223 Leveraging the long residence time of eIF5B on the ribos

224 Leveraging the microbiomes of marine animals and cutting

225 By leveraging the orthogonal R-loops generated by SaCas9 ni

226 t step in opening new avenues of research by leveraging the power of modern-technologies and machine-

227 Herein we show that leveraging the reactivity of benzylic C(sp(3))-H bonds t

228 Here, by leveraging the robotically controlled ink-jet deposition

229 ic antenna complexes activate dissipation by leveraging the sensitivity of the photophysics to the pr

230 Leveraging the spatial resolution of iEEG, we extended t

231 approach for reliable, stable BCI control by leveraging the stability of ECoG interfaces and neural p

232 Leveraging the synthetic modularity of ferritin-MOFs, we

233 ecting actively translating ORFs by directly leveraging the three-nucleotide periodicity of Ribo-seq

234 therwise intractable biological processes by leveraging the unique lipid and metabolite repertoire of

235 mproving our ability to predict, design, and leverage their unique properties for future applications

236 oints which Veissiere et al. may consider in leveraging their account to illuminate the dynamics by w

237 Atomically thin materials, leveraging their low-dimensional geometries and superior

238 iologically informed depression subtypes and leveraging them in the future for predicting treatment o

239 the developmental drivers of maturation and leveraging them to create more mature cardiomyocytes for

240 suggest that their dependency on ATR can be leveraged therapeutically and potentially expanded to BR

241 To leverage these advantages, we developed a method for scR

242 We introduce several loss functions that leverage these augmented data and demonstrate that these

243 ronment (MTME) genomic prediction models can leverage these datasets by exploring the correlation bet

244 A major goal in ecology is to leverage these patterns to identify the ecological proce

245 Finally, we leveraged these results to create a whole-body intracort

246 Leveraging these biomarkers to establish diagnosis and m

247 er CE and biometric parameters may allow for leveraging these clinical parameters for better case sel

248 Leveraging these data, we searched for anticoagulation f

249 Leveraging these findings will advance our mechanistic u

250 the glycocalyx and the future challenges in leveraging these tools into a novel tractable approach t

251 To leverage this dependency therapeutically, we developed a

252 We leverage this effect to alter the occupation of these pr

253 l-the number of expressed genes per cell-and leverage this measure of transcriptional diversity to de

254 As efforts progress to leverage this mechanistic knowledge toward rational ther

255 Here, we leverage this strain response to achieve coherent and lo

256 nd will guide protein engineering efforts to leverage this system for programmable DNA insertions in

257 We leverage this to train a simple and easily interpretable

258 We leveraged this concept to show that MM systemic seeding

259 used in emerging diagnostic applications, we leveraged this data source to test the confidence with w

260 Using condFDR analysis, we leveraged this enrichment to increase statistical power

261 Leveraging this additional information in a so-called te

262 By leveraging this innate immune function of erythrocytes,

263 nd outlines avenues for conducting research, leveraging this national resource in collaboration with

264 Leveraging this reference, an average of 402,573 previou

265 Leveraging this sensing mechanism, we demonstrate facile

266 acteristic of individual drugs, a finding we leverage to reveal specific on- and off-target effects o

267 ine how the AD brain network proteome can be leveraged to advance additional scientific and translati

268 quantitative descriptions of behavior can be leveraged to connect brain activity with animal movement

269 tes how small-scale experimental data can be leveraged to derive expectations of epidemiological impa

270 Thus, drug-induced AP can be leveraged to design evolutionary traps that selectively

271 The proposed framework is leveraged to design metallic metamolecules for arbitrary

272 Such information is being leveraged to develop new treatment strategies for CVD an

273 omparative studies of viral diversity can be leveraged to elucidate a virus's evolutionary dynamics.

274 gen atom abstraction and radical capture was leveraged to enable fluorination of allylic and benzylic

275 routine testing at health-care facilities is leveraged to estimate the effectiveness of an interventi

276 ween a chiral catalyst and the substrate are leveraged to exert enantiocontrol.

277 n artificial intelligence approach have been leveraged to extract information from clinical narrative

278 This design was leveraged to generate biosensors with specificity for di

279 data suggest that immune phenotypes might be leveraged to identify humans at highest risk of adverse

280 one remodeling, and how model systems can be leveraged to identify new therapeutic targets.

281 n such situations, social information can be leveraged to improve individual learning outcomes.

282 ecular structure of the synthesized HTMs was leveraged to investigate the role that the bridging unit

283 trate that resting state connectivity can be leveraged to produce generalizable markers of neurocogni

284 e demonstrate how the mechanical bond can be leveraged to promote the oxidative addition of an interl

285 penetration depths, which can be potentially leveraged to provide non-invasive quantitative measures

286 dels, suggesting that register data could be leveraged to systematically identify individuals at risk

287 s and their auxiliary therapeutics are being leveraged to target human cancers.

288 man kinases GSK-3beta, CDK-2, and CDK-4 were leveraged to try to improve the selectivity of the serie

289 rstood, and theoretically and experimentally leveraged, to elucidate AD pathophysiology.

290 g 1,800 highly tweeted bioRxiv preprints and leveraged topic modeling to infer the characteristics of

291 h) to expand our set of single-gene CNVs and leveraged two different approaches for validating these

292 Our investigation focuses on leveraging two motivations for solar adoption: self-inte

293 NO permeates this tunnel and leverages upon the gating side chains triggering the CD

294 Leveraging user interactions, ORSO provides a novel reco

295 d RV association tests have limited scope to leverage variant functions.

296 Leveraging well-characterized suppressive neural circuit

297 Here, we leverage whole-genome sequencing (WGS) and whole-genome

298 c data, theoretical models, and methods that leverage widely available monitoring data.

299 AZPs were leveraged within a generalizable framework to design con

300 rogeneity-Inspired Pre-Processing tOol) that leverages zero proportions to explain cellular heterogen