ライフサイエンスコーパス: license

1 d onto DNA in G1-phase (also known as origin licensing).

2 as now been made available under a CC BY 4.0 license.

3 freely available, distributed under a BSD-3 license.

4 ns Attribution 4.0 International (CC BY 4.0) license.

5 ProteinVR under the open-source BSD-3-Clause license.

6 for this article.Published under a CC BY 4.0 license.

7 implemented in C and released under the MIT license.

8 his software is distributed under the GPL v3 license.

9 Published under a CC BY 4.0 license.

10 ous heart attack.Published under a CC BY 4.0 license.

11 as now been made available under a CC BY 4.0 license.

12 written in Python under the open-source GPL license.

13 free of charge under the GNU AGPL V3 public license.

14 now been made available under a [CC BY 4.0] license.

15 hon package under the open-source Apache 2.0 License.

16 nd freely available under the permissive MIT license.

17 erver are made available with an open-source license.

18 now been made available under a [CC BY 4.0] license.

19 available under the GNU GPL v2.0 open source license.

20 etric proton MRI.Published under a CC BY 4.0 license.

21 gemBS is released under the GNU GPLv3+ license.

22 ibuted as open source under the BSD 3-clause license.

23 rce software released under the BSD 3-Clause License.

24 It is licensed under GNU General Public License.

25 are are distributed under an MIT open-source license.

26 as now been made available under a CC BY 4.0 license.

27 as now been made available under a CC BY 4.0 license.

28 tributed freely under the terms of the GPL-3 license.

29 emented in Python and licensed under the MIT license.

30 is distributed under the GNU General Public License.

31 for this article.Published under a CC BY 4.0 license.

32 The source code is licensed under the MIT License.

33 free biobanking tool published under the MIT license.

34 The application is distributed under an MIT license.

35 ree of charge under a permissive open source license.

36 uctures.jl is freely available under the MIT license.

37 rce licenses including LGPL and the Artistic License.

38 through Bioconductor via an open source MIT license.

39 cquired infections; no preventive vaccine is licensed.

40 e DDR, and several PARP inhibitors have been licensed.

41 th because no vaccine to combat CHIKF is yet licensed.

42 register their vehicles and obtain driver's licenses.

43 gins to prepare for S phase, known as origin licensing.

44 tion that invokes a mechanism we term quorum licensing.

45 ell interactions and CD40 signalling in cDC1 licensing.

46 , 14, 18C, 19A, 19F, and 23F, covered by the licensed 13-valent S. pneumoniae conjugate vaccine.

47 T4SBML is licensed under the Apache Software License 2.0.

48 censed under the terms of the Mozilla Public License 2.0.

49 ns Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to dow

50 ns Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to dow

51 ns Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to dow

52 ns Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to dow

53 ns Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to dow

54 B1 was prepared using a kit procedure with a licensed (68)Ge/(68)Ga generator.

55 cA(4) binding reorganises the structure to license a metal-dependent DNA nuclease activity specific

56 We then focused on arbidol, which is licensed abroad as an anti-influenza drug and exhibits a

57 gated the modes of action of arbidol, a drug licensed abroad to treat influenza infections.

58 Retrospective analysis of loss-of-license action rates for general surgeons who were initi

59 nd that the adjusted hazard rate for loss-of-license actions for surgeons who failed their first rece

60 The rate of loss-of-license actions was significantly higher for surgeons wh

61 is a significant predictor of future loss-of-license actions.

62 ed with a greater rate of subsequent loss-of-license actions.

63 odeoxycholic acid intolerance, conditionally licensed add-on therapy is with the FXR (NR1H4) agonist,

64 y which the reproductive system continuously licenses adult behaviors, including appropriate response

65 To date, no vaccine has been licensed against these organisms.

66 E, PsycINFO, AMED, PSYNDEX, websites of drug licensing agencies and pharmaceutical companies, and tri

67 untries, to identify the effect of voluntary licensing agreements on treatment uptake.

68 diminishes its interaction with STING, thus licensing an IFN-I response.

69 vailable for public use under an open source license and all datasets used in the paper are available

70 ensorpac is distributed under a BSD-3-Clause license and can be launched on any operating system (Lin

71 ly available for download under the GPL v3.0 license and can be run locally on Windows, Mac and Linux

72 open source R package under a permissive MIT license and includes detailed user documentation.

73 ware is licensed by the LGPL v.3 open source license and supports Windows, Mac and Linux platforms.

74 ropose that immunological cues and nutrients license and tune metabolic programmes and signalling net

75 Cooler is cross-platform, BSD-licensed and can be installed from the Python package in

76 against Plasmodium falciparum remains to be licensed and deployed.

77 rsal algorithm (Gretel) are open source, MIT licensed and freely available online at github.com/samst

78 KIR(+) cells to generate pure populations of licensed and unlicensed NK cells.

79 This commentary discusses the early licensing and deployment of a COVID-19 vaccine and how a

80 llular homolog [Myc], cyclin D1/3, chromatin licensing and DNA replication factor 1 [Cdt1]), concomit

81 nd whether the drugs prescribed reflected UK licensing and guidelines.

82 signaling may control DNA replication origin licensing and replisome stability thereby cell cycle pro

83 cial requirement of amino acid signaling for licensing and sustaining mTORC1 activation and functiona

84 ic interfaces (available under an Apache 2.0 license) and data updates made available four times a ye

85 mplemented in Python, released under the MIT License, and works on Linux, Windows, and MacOS.

86 ificantly correlated with patent filings and licenses, and others are correlated with different measu

87 t a potential therapeutic use for clinically licensed antagonists, such as anakinra, to prevent or tr

88 ry platform, the bilosome to entrap already- licensed antibiotics.

89 mal studies have suggested that trazodone, a licensed antidepressant, may protect against dementia.

90 cells displayed superior antitumor efficacy, licensed antigen-presenting cells, enhanced recruitment

91 e P. falciparum life cycle and describes how licensed antimalarials, clinical candidates, and newly e

92 resistance (AMR), and lack of new classes of licensed antimicrobials, have made alternative treatment

93 Licensed antivirals inhibit virus replication, but do no

94 JENVAC(R) is now licensed as a single dose JE vaccine.

95 JENVAC is now licensed as a single-dose Japanese encephalitis vaccine.

96 4-aminopyridine (4-AP) is used and licensed as a symptomatic treatment to ameliorate ambula

97 -1 receptor antagonist maropitant citrate is licensed as an antiemetic drug.

98 It is publicly available with an MIT license at github.com/optimusmoose/jsms.

99 b application and for download under a GPLv3 license at opig.stats.ox.ac.uk/webapps/scalop.

100 Bound to self-DNA/RNA, LL37 licenses autoreactivity by stimulating plasmacytoid dend

101 ecule(s) restrict BCR signaling strength for licensing BCR-induced CSR and whether deficiency of such

102 originally published under a CC BY-NC-SA 4.0 license, but has now been made available under a CC BY 4

103 The multi-platform software is licensed by the LGPL v.3 open source license and support

104 Eukaryotic replication origins are licensed by the loading of the replicative DNA helicase,

105 nks (TOP2-DPCs) in a direct-reversal pathway licensed by ZATTZNF451 SUMO2 E3 ligase and SUMOylation o

106 including a process whereby CD4(+) T cells 'license' cDC1 for CD8(+) T cell priming(12).

107 A p53-dependent origin licensing checkpoint normally ensures sufficient MCM loa

108 M loading with a severely compromised origin licensing checkpoint.

109 Confidence Interval: 0.71-0.85) and Nursing License Compact membership (Odds Ratio=0.23; 95% Confide

110 er numbers of border-states adopting Nursing License Compact membership (Odds Ratio=0.51; 95% Confide

111 ate Board of Medicine governance and Nursing License Compact membership.

112 ement measured variously as patents filed or licensed, companies founded, number of papers and books

113 We highlight licensed compounds, discuss the potential to shorten the

114 reatment in the home, and a broad library of licensed content.

115 While at the beginning of the epidemic no licensed countermeasures were available, several experim

116 nization (WHO) testing guidance for the only licensed dengue vaccine, CYD-TDV; and preliminary result

117 Licensed disease-modifying treatment focuses on ameliora

118 tion antidepressants, the lower range of the licensed dose achieves the optimal balance between effic

119 al acceptability in the lower range of their licensed dose.

120 For some drugs, higher than currently licensed doses might be tested in further trials, becaus

121 The resulting strand break licenses downstream events that lead to a DNA expansion

122 y, DNA-dependent monoubiquitinaton of FANCD2 licenses downstream events, while timely FANCD2 deubiqui

123 n in a rat spinal cord injury model with the licensed drug trifluoperazine inhibited AQP4 localizatio

124 market, there are no documented examples of licensed drugs being developed with the aid of a structu

125 As there are currently no licensed drugs for the treatment of dengue, these findin

126 The epidemic highlighted the need for licensed drugs or vaccines to quickly combat the disease

127 We long-listed licensed drugs with evidence of human safety, blood-brai

128 global response was to consider repurposing licensed drugs.

129 e code is free and open source under the MIT license, enabling institutions to install and users to e

130 on of immunomodulatory-associated genes, and licensed encapsulates promoted repopulation of recipient

131 infection with Staphylococcus aureus and, by licensing encephalitogenic Th17 cells, played a key role

132 to chromatin and upregulates DNA replication licensing factor CDC6.

133 ey to An. gambiae reproductive success as it licenses females to oviposit eggs developed after blood

134 The first gene therapy medicines have been licensed for marketing and several more are advancing to

135 The majority of vaccines currently licensed for poultry health include both modified live v

136 health threat, yet no products are currently licensed for prevention of primary C difficile infection

137 Live-attenuated influenza vaccine (LAIV) was licensed for prophylaxis of children 2-17 years old in E

138 (Cfz), an irreversible proteasome inhibitor licensed for relapsed/refractory myeloma, is associated

139 As extended release 4-AP is already licensed for symptomatic multiple sclerosis treatment, w

140 irst vaccine containing recombinant proteins licensed for the prevention of invasive meningococcal di

141 y developed orodispersible budesonide tablet licensed for the treatment of eosinophilic esophagitis.

142 for treating CSCR; however, this drug is not licensed for the treatment of patients with CSCR.

143 to indicate their donor statuses on drivers' license form which had a significant association with wi

144 ng IL-18-mediated inflammation overrides the licensing function of neutrophils, instead inducing iNKT

145 FHbp is a target of two licensed group B-directed meningococcal (MenB) vaccines.

146 c surface, to identify microbial traits that license growth and survival in this spatial niche.

147 vo, the localized activity of the clinically licensed growth factor BMP-2.

148 The trial administered a licensed Hepatitis B vaccine at 0, 1 and 6 months.

149 f a DNA break to the catalytic domain, which licenses HPF1 binding and PARP2 activation.

150 We confirmed that licensed human NK cells are greater in number in periphe

151 potential mechanisms of enhanced function in licensed human NK cells.

152 hinders worldwide implementation of the only licensed human Q fever vaccine.

153 There currently is no licensed human vaccine against EBOV.

154 als (83%) identified as teaching with median licensed ICU beds of 70.

155 e first dengue virus vaccine, Dengvaxia, now licensed in 20 endemic countries, the EU and the USA, pr

156 BAT product was US-licensed in 2013.

157 The first dengue vaccine was licensed in 2015 but its performance depends on serostat

158 ountry in 2008, and a nonavalent vaccine was licensed in 2018.

159 combinant zoster vaccine, which is currently licensed in certain countries for adults aged 50 years a

160 Bivalent and quadrivalent HPV vaccines were licensed in the country in 2008, and a nonavalent vaccin

161 monly prescribed antidepressants were either licensed in the UK for use in children and young people

162 There is currently no typhoid vaccine licensed in the United States for use in children <2 yea

163 ered and selective introduction of voluntary licensing in different countries, to identify the effect

164 concerns regarding the utility of currently licensed inactivated influenza virus vaccines and novel

165 e is available under a choice of open source licenses including LGPL and the Artistic License.

166 The effect of licensing increased over time, and was largest in the se

167 ing trade-offs when they allow exercising to license indulgence afterward (balancing between goals),

168 We further found that BMPR signaling licenses inflammation-associated Langerhans cell/DC to g

169 on drives accumulation of neutrophils, which license iNKT cells to negatively regulate autoreactive B

170 n, the DR3 ligand TNF-like protein 1A (TL1A) licenses innate TNF-alpha production in the absence of c

171 esistance to CAB and cross-resistance to all licensed integrase inhibitors.

172 vaccine has not been developed, and the only licensed intervention is passive immunoprophylaxis of hi

173 egulate the G1/S transition after the origin licensing is complete.

174 ccharomyces cerevisiae by deregulated origin licensing is non-random and defined by broad domains tha

175 While the biochemistry of origin licensing is understood, the mechanisms that promote an

176 To date, there is no licensed KSHV vaccine.

177 The currently licensed LAM test, Alere Determine TB LAM Ag ('LF-LAM'),

178 ists, tax and real estate data, professional licensing lists, and ancestry websites, and exposure mea

179 ts with the NPC1 cholesterol transporter and licenses lysosomal cholesterol export.

180 This licensing mechanism enables the cell to discriminate chr

181 high lethality combined with the paucity of licensed medical countermeasures makes EBOV a critical h

182 The antipsychotic clozapine, the only licensed medication for treatment-resistant schizophreni

183 ntified potential targets for repurposing of licensed medications: using Mendelian randomization, we

184 There are as yet no licensed MERS vaccines or therapeutics.

185 phalitis from cerebrospinal fluid (CSF) in a licensed microbiology laboratory.

186 pen source software, available under the MIT License (MIT).

187 talk between molecular 'rulers' and 'clocks' licenses mitotic exit only after proper chromosome separ

188 selectively binds mRNA maturation marks and licenses mRNA for nuclear export by loading the export f

189 ngements and non-participation in reciprocal licensing networks.

190 respiration for cytolytic function, whereas licensed NK cells demonstrated metabolic reprogramming t

191 protein analysis, we found that unstimulated licensed NK cells have increased expression of the glyco

192 of education in which enhanced glycolysis in licensed NK cells supports proliferative and cytotoxic c

193 atural killer (NK) cell education results in licensed NK cells with heightened effector function agai

194 is enables the virus to evade recognition by licensed NK cells.

195 was required to suppress the cytotoxicity of licensed NK cells.

196 However, it is unclear whether current licensed non-egg-based vaccines generate superior protec

197 n in a proteolysis-independent manner; NS2B3 licensed Nrf2 for lysosomal degradation.

198 ify Bmh1 as a key player in the mechanism of licensing of chromosome compaction in mitosis.

199 cells and HLA-DQ8 have a crucial role in the licensing of cytotoxic T cells to mediate intestinal epi

200 to kinetochores, mitotic exit, cytokinesis, licensing of DNA replication by re-activating pre-replic

201 Licensing of encapsulated MSCs with inflammatory cytokin

202 Licensing of eukaryotic origins of replication requires

203 We postulate that metabolic licensing of histone acetylation provides another layer

204 s collected before and during the 4-year OPO licensing office contract.

205 ecific department of motor vehicle (DMV) and licensing offices, where people register their vehicles

206 her higher or lower doses than the currently licensed ones might be more appropriate, and derived dos

207 based on the Vi capsular polysaccharide are licensed or in development against typhoid fever.

208 activation defects, differential replication licensing or X versus Y chromosome size, but rather to '

209 nce (MCM) proteins facilitate replication by licensing origins and unwinding the DNA double strand.

210 for several therapies, none of these is yet licensed, partly because of immune suppressive side-effe

211 ltural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolin

212 In addition, because the current licensed poxvirus vaccines can cause serious adverse eve

213 l in which the cell cycle is controlled by a licensing process, the rate of which is related in a sim

214 ite recent progress on vaccines, and with no licensed prophylaxis or treatment available, case manage

215 We have developed a GPL-3 licensed R package and a Shiny Application to enable use

216 m samples from healthy adults immunised with licensed rabies vaccine, were generated.

217 mal acceptability for the SSRIs in the lower licensed range between 20 mg and 40 mg fluoxetine equiva

218 that sequential ATPase and GTPase activities license release factors Rei1 and Yvh1 to trigger Arx1 an

219 is presently limited in scale by interstate licensing restrictions and reimbursement barriers.

220 HuEPO) therapeutic protein products; one FDA-licensed rHuEPO originator biological product, three rHu

221 ce products or approved biosimilars from non-licensed rHuEPO products on the basis of differences in

222 igned to be more genetically stable than the licensed Sabin monovalent OPV2, have been developed to r

223 Finally, we confirm that currently licensed seasonal influenza vaccines can boost preexisti

224 is cross-platform, open-source and free (MIT licensed) software.

225 European Medicines Agency recommended a post-licensing study assessing the cardiovascular safety of f

226 hipment trade records, slaughterhouse export licenses, subnational agricultural statistics, and data

227 the 1960s, a single class of agent has been licensed targeting virus-encoded ion channels, or 'virop

228 largely due to the low efficacy of the only licensed TB vaccine, Bacillus Calmette-Guerin (BCG) agai

229 Bacillus Calmette-Guerin (BCG), the only licensed TB vaccine, provides variable efficacy against

230 xpansion compromised cell yield, this method licensed Th17 cells to eradicate large tumors to a great

231 abbreviated, 4-day ex vivo expansion method licenses Th17 cells to confer long-lived immunity agains

232 Importantly, TIDC were required to license the cytotoxic activity of tumor CD8(+) T cells,

233 gene mutations of varied functional classes license the NLRP3 inflammasome to generate a common phen

234 Atara Biotherapeutics licensed the bank of third-party EBV-CTLs from Memorial

235 The mitotic kinase NEK7 licenses the assembly and activation of the NLRP3 inflam

236 nstead of bypassing it; thus, ATP hydrolysis licenses the MutS mobile clamp to rebind the mismatch.

237 e that the druggable Notch signaling pathway licenses the Th2 response in allergic airway inflammatio

238 t that MVt undergoes a conformational change licensing the formation of a protruding sub-domain incor

239 There are no widely available licensed therapeutics against SARS-CoV-2, highlighting a

240 No vaccines or licensed therapeutics currently exist to protect humans

241 There are as yet no licensed therapeutics for the COVID-19 pandemic.

242 There are no licensed therapeutics or vaccines available against Zika

243 the severity of CHIKV disease, there are no licensed therapeutics.

244 There are no licensed therapies available.

245 e package is freely available under a public license through the Comprehensive R Archive Network.

246 e subversion as a fundamental mechanism that licenses tissue inflammation in asthma.

247 originally published under Nature Research's License to Publish, but has now been made available unde

248 icle was originally published under standard License to Publish, but has now been made available unde

249 sing machinery is a dynamic assembly that is licensed to cleave only when all protein factors come to

250 ing developed for over four decades but none licensed to date.

251 w, recombinant protein-based vaccine that is licensed to protect against invasive group B meningococc

252 Targeted therapies licensed to treat gastric cancer include trastuzumab (HE

253 fficult, from the financing, development and licensing to programme implementation and public accepta

254 spase-8-dependent cleavage of N4BP1, thereby licensing TRIF-independent TLRs to produce higher levels

255 It is licensed under GNU General Public License.

256 CRNT4SBML is licensed under the Apache Software License 2.0.

257 n open-source tool implemented in Python and licensed under the MIT license.

258 The source code is licensed under the MIT License.

259 LabxDB is licensed under the terms of the Mozilla Public License 2

260 t how the regulation of methionine transport licenses use of methionine for multiple fundamental proc

261 This program is under GNU General Public License v3.0.

262 isms and implications of shortcomings of the licensed vaccine and describe the structure and attribut

263 explore the benefits of extended release of licensed vaccine antigens into skin to increase immune r

264 No licensed vaccine exists against visceral leishmaniasis (

265 To date, no licensed vaccine exists for prevention of human disease,

266 children, and the elderly, and currently, no licensed vaccine exists.

267 ication with a case study of Hecolin(R), the licensed vaccine for hepatitis E virus (HEV).

268 Ervebo is the first licensed vaccine for prevention of Ebola virus disease.

269 There also is currently no licensed vaccine for this potentially fatal pathogen, fu

270 Bacillus Calmette-Guerin (BCG) is the only licensed vaccine for tuberculosis (TB), and is also used

271 tly at various stages of development, but no licensed vaccine is available in the United States.

272 development, we remain without a clinically licensed vaccine or immunotherapeutic to reduce the burd

273 pediatric respiratory pathogen that lacks a licensed vaccine or suitable antiviral drug.

274 To date, there is no licensed vaccine or therapeutic intervention available f

275 While vaccine development is warranted, a licensed vaccine, specific for human use, against EHEC i

276 l threat, there are no specific therapies or licensed vaccine.

277 Currently licensed vaccines against the common otopathogen Strepto

278 es of Lassa fever, together with the lack of licensed vaccines and limited and partially effective in

279 However, licensed vaccines are available only against poliovirus

280 To date, no licensed vaccines are available to prevent Lassa virus (

281 Many licensed vaccines confer protection by inducing long-liv

282 bal disease burden, no approved therapies or licensed vaccines exist.

283 No licensed vaccines or antiviral therapeutics are availabl

284 th human metapneumovirus in children, and no licensed vaccines or drugs exist for human metapneumovir

285 The lack of licensed vaccines or therapeutic approaches against NiV

286 as proven difficult and there are no broadly licensed vaccines or therapeutics.

287 There are currently no licensed vaccines or therapies.

288 find major effectiveness differences between licensed vaccines used among the elderly during the 2018

289 We have compared four licensed vaccines with known safety profiles, as well as

290 re needed to improve coverage with currently licensed vaccines.

291 ccines or to routinely measure NA content in licensed vaccines.

292 er the permissive open source Mozilla Public License Version 2.0.

293 ted in C++ and is available under the Apache License Version 2.0.

294 is distributed under the GNU General Public License version 3 and is accompanied by example files an

295 MHC I also undergo education, referred to as licensing, which causes them to become more responsive t

296 using ReadiBand wrist actigraphs, which are licensed with the Sleep, Activity, Fatigue, and Task Eff

297 It is freely available under a 2-clause BSD license, with bindings for the C++, C, R, and Python pro

298 If a SARS-CoV-2 vaccine is licensed within 18 months of the start of the pandemic,

299 Thus, Sir2-mediated attenuation of origin licensing within both euchromatin and telomeric heteroch

300 Consent via driving license would seem to be a good potential mode of obtain