ライフサイエンスコーパス: life

1 nly by an expectation of improved quality of life.

2 eatening human health and overall quality of life.

3 changes in cognition in the fifth decade of life.

4 ciated with a lower risk of frailty later in life.

5 e symptoms that negatively impact Quality of Life.

6 with increased specificity and extended half-life.

7 that occur as a normal attribute of aerobic life.

8 identified in organisms from all domains of life.

9 the control diet for the remainder of their life.

10 truments, and substantially improved mission life.

11 idly absorbed with a 14.5-hour terminal half-life.

12 -1 replication but need to be maintained for life.

13 ,232) followed across the first 2 decades of life.

14 ns, increasing in six days the mangoes shelf life.

15 e in learning and memory function throughout life.

16 strongly associated with a better quality of life.

17 wheezing and eczema in the first 3 years of life.

18 Respiration signals are a vital sign of life.

19 elping to decipher the complex mechanisms of life.

20 are two fundamental nongenetic attributes of life.

21 ptibility to infection observed during early life.

22 for desiccation resistance to enhance shelf life.

23 ended infection with that subtype throughout life.

24 edstocks for industrial production and daily life.

25 modification of RNA found in all kingdoms of life.

26 rules that govern skin inflammation in early life.

27 bronchiolitis during the first six months of life.

28 ed with significant impairment of quality of life.

29 ed the evolution of early forms of RNA-based life.

30 was no significant difference in quality of life.

31 ith progressive heart valve disease early in life.

32 energy density, high safety, and long cycle life.

33 and cause-specific mortality in early adult life.

34 ailable genome-scale data across the tree of life.

35 ls to be vulnerable to lung disease in later life.

36 ing dental restoration with extended service life.

37 but no significant difference in quality of life.

38 t health care burden and impaired quality of life.

39 nguage is distributed symmetrically early in life.

40 ryonic period but perished in early juvenile life.

41 ubstantially diminishes patients' quality of life.

42 st time) N(2) respiration limits for complex life.

43 rofessor discusses the challenges of faculty life.

44 ased risk of cardiovascular disease later in life.

45 elop oral tolerance to food antigen in early life.

46 s, and thus adapts the cells to an avascular life.

47 ainless steel, plastic, and nitrile for half-life 2.3-17.9 h.

48 ne-4,6(5H,7H)-dione), has a long plasma half-life (~ 24 hours) in mice, suggesting possible binding t

49 MRI images obtained on day of life 4-7 were scored according to standardized injury cr

50 er accelerating reproduction following early-life adversity leads to higher lifetime reproductive suc

51 Accordingly, the Life After Pediatric Sepsis Evaluation investigation was

52 come after aneurysm treatment and quality of life after SAH influenced the preferred screening strate

53 py techniques are used by researchers in the life and biomedical sciences.

54 ffort is the modulation of autoantibody half-life and blocking access of autoantibodies to fragment c

55 breast reconstruction can restore quality of life and body image, its morbidity remains substantial.

56 s who were diagnosed with clinical AD during life and had a diagnosis of AD confirmed post-mortem by

57 ated with long term neurological deficits in life and have also been associated with dysbiosis.

58 cles (AVs) have the potential to shape urban life and significantly modify travel behaviors.

59 compound suffered from a short in vivo half-life and suboptimal potency in whole blood.

60 ences, and goals, with a focus on quality of life and symptom management.

61 We focus on four key rules of life and their interactions: the temperature dependence

62 ening, greatly decrease patient's quality of life, and are a substantial burden on the healthcare sys

63 of bulls for lifetime net merit, productive life, and livability.

64 est aspirations to "enhance health, lengthen life, and reduce illness and disability," the US biomedi

65 ays an important role in daily anthropogenic life, and the processes by which this fixation occurs ha

66 the non-arbitrary elemental stoichiometry of life; and maximization of limiting resource use efficien

67 Environmental limits of animal life are invariably revised when the animals themselves

68 ffect on lifespan, healthspan and quality of life as patients age worldwide, highlighting the need to

69 imary outcome was fibroid-related quality of life, as assessed by the score on the health-related qua

70 ms, sexual function and impact on quality of life, as well as measurement of prostate volume, uroflow

71 Form-36 evaluated health-related quality of life at 1-year follow-up.

72 nction- and mental health-related quality of life at 2-3 months and 6 months post-hospital discharge.

73 higher scores indicating a better quality of life) at 2 years; adjustment was made for the baseline s

74 During the root phase of the tree of life, before the last common ancestor of life (LUCA), ex

75 26-item World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire (items related to

76 not only through improvements in quality of life but also in terms of survival.

77 ssion affects all aspects of an individual's life but evidence relating to the causal effects on heal

78 d anti-MDA increased during the first 2 y of life, but IgM anti-PC in contrast to IgM anti-MDA was st

79 production and degradation and measure half-life by quantifying the rate of decay after experimental

80 redict and identify poor performance in real life.(C) RSNA, 2020Keywords: Breast, ScreeningSee also t

81 vestigating effects of fetal growth on later-life cardiometabolic disease because birth weight is onl

82 Provider COC had a greater effect on end-of-life care expenditures than site COC did, which indicate

83 spice services are likely to optimise end-of-life care for patients with haematological malignancies.

84 End of life care is often inadequate for people with dementia.

85 al delivery of protein drugs is considered a life-changing solution for patients who require regular

86 portance of the noradrenergic system in late-life cognition.

87 Analogous systems are studied as early-life compartmentalization mechanisms, for applications a

88 ay, which resolves ambiguity about the after-life consequences of this key plant functional trait by

89 tuates the free-energy principle within real-life cultural processes, thereby enriching both sociocul

90 d peripheral homeostasis in the CD4+ Th cell life cycle and invariant NK (iNK) T cell development and

91 Seventy-one unique life cycle assessment (LCA) studies that quantify the en

92 r crescentus employs a specialized dimorphic life cycle consisting of two differentiated cell types.

93 However, annual life cycle environmental impacts of crop production at c

94 imate change causes changes in the timing of life cycle events across all trophic groups.

95 Models that characterize life cycle greenhouse gases from electricity generation

96 cated that significant variations existed in life cycle GWP, EU, and AD among counties and across yea

97 There are currently limited life cycle impact assessment methods existing for assess

98 iruses, we examined key aspects of the viral life cycle in three-dimensional (3-D) human airway tissu

99 in a consistent decrease in the C. difficile life cycle in vivo, it was able to attenuate an overly r

100 environmental impacts throughout the entire life cycle of packaging and FSW were analyzed.

101 replication, housing key steps in the virus life cycle that warrant further investigation.

102 pathogens are able to compartmentalize their life cycle to provide favorable conditions for replicati

103 h impacts of fluoropolymers throughout their life cycle(s).

104 tage (and perhaps other stages) of the viral life cycle, based on several lines of evidence.

105 To successfully complete its life cycle, Chlamydia must evade both intracellular inna

106 inae) bore into tree xylem to complete their life cycle, feeding on symbiotic fungi.

107 for HPV-mediated carcinogenesis and the HPV life cycle.

108 fill its multifunctional role during the AAV life cycle.

109 Given their catadromous life-cycle, and global commercial and cultural importanc

110 Due to their long and unique life cycles, these arthropods likely evolved robust epig

111 Late-life declines in avian song, and possibly other sexual t

112 al reasons, lack of motivation, or competing life demands.

113 of recurrent stroke, disability, quality of life, dementia and hospital care costs stratified by hae

114 ritical insights into the precursors of late-life dementias.

115 o improve with time, while mental quality of life did not differ significantly from the general popul

116 y the score on the health-related quality-of-life domain of the Uterine Fibroid Symptom and Quality o

117 0 to 100 scale-and health-related quality of life-EQ-5D-5L on a 0 to 1 scale-using linear regression

118 esity to investigate the importance of early life ER stress in the nutritional programming of this me

119 rgic PRS appeared to interact with childhood life events in relation to unemotional scores.

120 and Death) clock, which accurately predicts life expectancy and the efficacy of a lifespan-extending

121 especially in light of the increases in the life expectancy and the incidence of comorbidities in th

122 rmine the impact of TAVR valve durability on life expectancy in a cohort of low-risk patients similar

123 umor insensitivity to chemotherapy, shortens life expectancy of cancer patients.

124 festyle risk factors equally correlated with life expectancy, with smoking being significantly worse

125 schooling years) on a variety of disease and life-expectancy outcomes.

126 e drawn strong associations between paternal life experiences and offspring health and disease outcom

127 prevalence of ADHD in association with early life exposure to PFOS and PFOA.

128 ome apparent that the diversity of microbial life extends far below the species level to the finest s

129 anges occurred later in the fourth decade of life, followed by hippocampal atrophy and changes in cog

130 The parasite clearance half-life following artemether-lumefantrine treatment was 6.7

131 e was associated with up to 6.3 years longer life for men and 7.6 years for women; however, not all l

132 ogical costs of childbearing influence later life frailty.

133 randomized trials, but the quantity of early-life gluten exposure has been a major focus of preventio

134 r restoring the pursuit of individual valued life goals in the face of persistent pain, and further i

135 o engaged in a larger number of CTs in daily life had lower connectivity in the posterior temporal la

136 Quality of life has been proposed as the fourth 90 to complement th

137 Meaning in life has long been a mystery of human existence.

138 mplies CRESS viruses infecting multicellular life have evolved independently on at least three occasi

139 -known cofactors in fundamental processes of life, have stimulated interest as synthetic models of na

140 ics of early growth and its links with later-life health outcomes.

141 anode and the high-voltage cathode for long-life, high-energy-density rechargeable Li metal batterie

142 t, we show that the selection of alternative life histories depends on both the mean and variance of

143 on by clinicians treating women with diverse life histories.

144 LS hypothesis suggests that the link between life history and personality may only emerge under certa

145 strategy, temporal discounting, the Arizona life history battery, past and current health, disgust s

146 eded that incorporate various ecological and life history components of animals life that may include

147 s of 47 teeth from 15 individuals with known life history events and were able to detect reproductive

148 We then test whether life history explains variation in species' niches and n

149 indings clearly show that human activity and life history interact to influence range changes in mamm

150 relatively homogenous group in terms of age, life history stage and social norms(3,4).

151 different causes of mortality due to traits, life history stages, or locations.

152 Understanding life history strategies in deep-sea environments is lack

153 Resource availability models arising from life history theory suggest that socioeconomic condition

154 Maine, USA and evaluated additional data on life history timing and migratory connectivity from prev

155 To describe migration and life history timing, we deployed light-level geolocators

156 on modalities, leading to changes in complex life history traits, such as longevity.

157 een avian physiology, ecology, behaviour and life history, while demonstrating the importance of demo

158 was not related to any of the psychological life history-relevant variables measured (including shor

159 ental factors operating during separate host life-history events.

160 mechanism that seems to induce this adaptive life-history plasticity.

161 experiments to examine the physiological and life-history responses of individual red squirrels to fl

162 time-limiting step for research on the early life-history stages of corals.

163 ance can act as an agent of selection on key life-history strategies and promote the evolution of soc

164 Since LINbase leverages the concept of Life Identification Numbers (LINs), which are codes assi

165 low-up which also correlated with quality of life improvements.

166 y the invasive administration and short half-life in blood circulation.

167 s to extract the three worldviews or ways of life in Great Britain.

168 Moreover, geography, especially life in rural areas, appears to have a greater correlati

169 reported difficulties adapting to their new life in the UK, including within their role as a nurse,

170 This limitation has led to models of early life in which the first cells used simpler types of memb

171 ome of the dynamic processes that constitute life including cell development, movement, and division.

172 fascinating but poorly understood branch of life, including species with a highly unusual body plan

173 ctivities of complex enzymes is critical for life, including transcribing, replicating and repairing

174 Eating disorders are life-interrupting psychiatric conditions with high morbi

175 Maintaining a healthy proteome throughout life is critical for proper somatic stem cell function,

176 inant of prognosis, mortality and quality of life, is diminished in patients with chronic obstructive

177 However, it is labeled with the short half-life isotope (11)C.

178 s scientists, fueling the dream of mimicking life-like motion and tasks in untethered, man-made devic

179 c cancer, these patients require specialised life-long care, with implications for their families.

180 Maintaining life-long health behaviors may be crucial to reduce late

181 However, the requirement for life-long immunosuppression and its associated side effe

182 donated pancreas tissue and (b) the need for life-long immunosuppression.

183 Two-year therapy prevented a 1-month-of-life loss, and revealed bevacizumab, ranibizumab, and af

184 lion deaths or 20.5 trillion person years of life lost would be valued at $10.2 to $17.5 trillion.

185 of life, before the last common ancestor of life (LUCA), exit tunnel evolution is dominant and unrem

186 ore (primary efficacy end point), quality of life, LV structural remodeling ( EF >5% and ESV 10%) and

187 a respiratory PedsQL, a pediatric quality of life measure, greater than or equal to 5 or asthma diagn

188 found no effect on health-related quality of life measures, perceived thirst or xerostomia, or dietar

189 nge from baseline in itch-related quality-of-life measures, the percentage of patients with an improv

190 entified developmental trajectories of early-life microbiome composition, as well as predominant bact

191 y of mortality and health-related quality of life morbidity for children encountering community-acqui

192 role of leptin in the associations of early-life nutrition and adult cardiometabolic outcomes.

193 -specific serum IgG titers waned with a half-life of 49 days, nAb titers and avidity increased over t

194 is a major stressor that generally subverts life of aerobic species and is a prominent feature of pa

195 as 0.29 +/- 0.09 min-1, equivalent to a half-life of approximately 2.4 minutes.

196 leviate suffering and improve the quality of life of children with serious disease and increase suppo

197 reversible pulmonary failure threatening the life of COVID-19 patients.

198 These findings show that prolonging the half-life of Nkx3.1 reduces proliferation, enhances DNA end-l

199 apy-resistant phenotype, stabilizes the half-life of p53 and uses p53 to initiate a slow-cycling stat

200 comparable to those of APOBEC3G with a half-life of roughly 6 h postinfection, demonstrating that Vi

201 its ability to persist within cells for the life of the host.

202 des a versatile remedy for the limited cycle life of the Zn anode.

203 nti-bacterial agent for prolonging the shelf life of tuna fish.

204 with sterile males also showed enhanced late-life offspring production when allowed to reproduce, ind

205 evealed the extensive diversity of bacterial life on earth.

206 plants was accompanied by new adaptations to life on land, including the evolution of stomata-pores o

207 assessing environmental mastery, purpose in life, optimism, resilient coping, and depressive symptom

208 ial-immune interactions underlying the early-life origins of allergic disorders, as well as immune me

209 g/stripping (10 mAh cm(-2) ), and long cycle life (over 10 000 cycles).

210 ic Outcomes (Child Health-Related Quality of Life, Pain, Survival, and Communication).

211 e suppression for the first 4 or 12 weeks of life prevented abnormal molecular and cognitive phenotyp

212 t to both symptom alleviation and quality of life (QoL) in major depressive disorder (MDD).

213 ung Cancer 13 (QLQ-LC13) assesses quality of life (QOL) in patients with lung cancer and was the firs

214 symptom burden and a deteriorated quality of life (QOL), with uncertain prognosis and limited treatme

215 ppression, immune activation, and quality of life (QoL).

216 re, pruritus score, sleep score, Dermatology Life Quality Index and IgE.

217 Patient-Oriented Eczema Measure, Dermatology Life Quality Index, Numeric Rating Scale pruritus).

218 h and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13) assesses qu

219 hemical mixtures has focused mainly on early life rather than adolescence, a potentially important de

220 Brain structure in later life reflects both influences of intrinsic aging and tho

221 ned and used.SIGNIFICANCE STATEMENT Everyday life requires flexibility in switching between several r

222 alth behaviors may be crucial to reduce late-life risk of dementia.

223 in their self-expression also report greater Life Satisfaction.

224 mental cost-effectiveness ratio (USD/year-of-life saved) was <$940 (South Africa) and <$750 (Malawi).

225 Intestinal transplantation (ITx) can be life-saving for patients with advanced intestinal failur

226 ung transplantation (LTx) remains a critical life-saving operation.

227 al aspects) and the 5-item Satisfaction with Life Scale (SWLS) in the clinic visit.

228 uestionnaire and the Professional Quality of Life Scale were used in this study.

229 ations indispensable in many applications of life science.

230 lth record AF (EHR-AF) score in IBM Explorys Life Sciences, a multi-institutional dataset containing

231 This has now been corrected to: "Division of Life Sciences, State Key Laboratory of Molecular Neurosc

232 ols continues to drive major advances in the life sciences.

233 aeal organisms across the archaeal domain of life show surprising levels of diversity at many levels-

234 sodium without adverse safety or quality of life signals, a larger trial, with modifications to impr

235 We used this model to project the effective life span of antibiotics and the number of gonorrhea cas

236 , this strategy could increase the effective life span of antibiotics by 0.94 years, which is equival

237 and inhibited quiescence, which explains the life span shortening.

238 ls using CD19-Cre, female mice have a normal life span without obvious illness.

239 ill be available to support the reproductive life span.

240 petence and developmental changes across the life span.

241 or high-risk HPV18 E7 to extend keratinocyte life span.

242 which likely contributes to the health- and life-span extending effect of IIS pathway downregulation

243 However, in real-life spreading processes, pathogens often evolve in resp

244 essors on immune system development in early life stage fishes.

245 cence, a potentially important developmental life stage.

246 ion of nitrate drives shifts in the dominant life-stage of the population.

247 lization resulted in albinism throughout all life stages and throughout all cells and tissues of this

248 t is not common except in highly susceptible life-stages, and that single infections are the most com

249 cal significance of lysogeny and other viral life strategies in nature(6,8-15).

250 In the CNS, early-life stress (1) decreased 2-arachidonoyl glycerol and ar

251 mmune network hypothesis suggests that early-life stress initiates a positive feedback loop between p

252 d completed paired health-related quality of life surveys.

253 ding suggests that maternal effects on early life survival such as maternal age may act through their

254 an donation prior to a planned withdrawal of life-sustaining care in an imminently dying patient.

255 illness frequently use Physician Orders for Life-Sustaining Treatment (POLST) to document treatment

256 Using global supply data and 1,879 life tables from 103 countries, we test for these effect

257 ls of S100A8-A9 during the first 3 months of life than fecal samples from adults; levels decreased to

258 gical and life history components of animals life that may include sex differences in exposure to pre

259 s indicated that cytoplasmic Cx43 had a half-life that was 50% shorter than membrane-associated Cx43.

260 his hypothesis, at the time of the origin of life there were only seven primordial amino acids: Valin

261 o not understand, malaria becomes severe and life threatening.

262 r exhibit mild symptoms or progress toward a life-threatening acute respiratory distress syndrome (AR

263 cute bronchospastic episode can experience a life-threatening asthma event.

264 Rationale: Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disorder in which infla

265 dysfunction is a hallmark of preeclampsia, a life-threatening complication of pregnancy characterised

266 autoimmune cytopenia (AIC) is a potentially life-threatening complication, but studies focusing on l

267 population, and its recrudescence can cause life-threatening disease in immunocompromised individual

268 high expression of TYK2, are associated with life-threatening disease; and transcriptome-wide associa

269 rombotic thrombocytopenic purpura (TTP) is a life-threatening hematological condition associated with

270 cer has come at a cost of increased risks of life-threatening infectious complications.

271 nogenic diseases with severe and potentially life-threatening manifestations.

272 The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis.

273 d from respiratory illness but can develop a life-threatening multisystem inflammatory syndrome (MIS-

274 Human immunodeficiency virus 1 (HIV-1) is a life-threatening pathogen that still lacks a curative th

275 Cytokine release syndrome (CRS) is a life-threatening treatment-related toxicity that limits

276 Pathogenic bacterial biofilms can be life-threatening, greatly decrease patient's quality of

277 gan system and can be treatment-limiting and life-threatening, such as diabetic ketoacidosis, which a

278 on, recurrent infections that can be mild to life-threatening.

279 s to Open Occluded Coronary Arteries) severe/life-threatening/moderate and TIMI (Thrombolysis in Myoc

280 provide a way for evolution to occur and for life to arise from non-living systems.

281 f the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire (scores range from 0 to 100

282 rimental impact on vision-related quality of life (VRQoL), but it is still unclear how this relations

283 Vision-related quality of life was measured using Rasch-transformed scores from th

284 History of infection during first year of life was not associated with ALL risk (odds ratio (OR) =

285 hysical and mental health-related quality of life was significantly reduced among firearm injury surv

286 e oxygenation survivors' physical quality of life was worse than population norms but tended to impro

287 Her accomplishments and astounding life were lost to history for more than one hundred year

288 GI) symptoms, dietary intake, and quality of life were measured.

289 ho transcription and diminished protein half-life, whereas cleavage by ADAM proteases was not modifie

290 for natural polypeptides, building blocks of life, which are fragile and difficult to handle.

291 decay (caries), affect health and quality of life, with associated costs to society(3).

292 e to select MVA-related pathologies later in life, with predisposition to sarcopenia correlating with

293 r enasidenib, leading to improved quality of life without a reduction in AML disease burden.

294 threshold of US$500 per disability-adjusted life-year (DALY) averted for our main analysis.

295 rotocol biopsy yielded more quality-adjusted life years (QALYs) at lower cost.

296 ion model that can estimate quality-adjusted life years and costs resulting from improvements in a qu

297 ma is the first cause of disability-adjusted life years worldwide, yet most attention has focused on

298 results in 10.5 million disability-adjusted life-years lost globally.

299 s projected to produce a gain of 318 million life-years.

300 Extreme environments test the limits of life; yet, some organisms thrive in harsh conditions.