ライフサイエンスコーパス: ligand

1 enyl-1,10-phenanthroline; sq = semiquinonate ligand).

2 ies all hydrogen-bonding requirements of the ligand.

3 linositol (LPI) is its only known endogenous ligand.

4 he dangling phosphonic groups of the tPa(4-) ligand.

5 he electronegativity of the unique aspartate ligand.

6 ility to internalize together with the bound ligand.

7 e fluorinated pyridine moiety to the carbene ligand.

8 vity-determining step induced by the optimal ligand.

9 condary, serving as a mandatory coactivating ligand.

10 ng the excess of the >P(O)H reagent as the P-ligand.

11 opening by PIP(2) , the probable activating ligand.

12 y is linked to a PPARalpha-specific proximal ligand.

13 neage-specified trophectoderm expresses EFNA ligands.

14 the FZD/LRP heterodimeric receptors and Wnt ligands.

15 r with many "orphan" receptors without known ligands.

16 xpression of related chemokine receptors and ligands.

17 mediated endocytosis by hepatocyte targeting-ligands.

18 of protein functions such as the binding of ligands.

19 thiolate nanoplatelets with cysteine surface ligands.

20 rotein complexes and their interactions with ligands.

21 which are likely coordinated by carboxylate ligands.

22 be predicted from that of their constituent ligands.

23 istors based on Ru-complexes of azo-aromatic ligands.

24 r the design of new long-residence-time TSPO ligands.

25 e classes of anionic mesoionic carbene-based ligands.

26 for nonlectin proteins that bind multivalent ligands.

27 expression of Cck2r (a GPCR) and Delta-like ligand 1 (DLL1), is a label-retaining cell that undergoe

28 Programmed death ligand 1 (PD-L1) and PD-L2 are ligands for PD-1; the for

29 face expression of CD86 and programmed death ligand 1 (PD-L1).

30 The interaction of programmed cell death 1 ligand 1 (PDL1) with its receptor programmed cell death

31 Tumor programmed death-ligand 1 expression and MSI-H/MMR-D status were not asso

32 geting the BMME with P-selectin glycoprotein ligand-1 (PSGL-1)-targeted BTZ and ROCK inhibitor-loaded

33 ls (and their expression of programmed-death-ligand-1) in spinal cord-draining lymph nodes and decrea

34 iation between increased levels of chemokine ligand 2 (CCL2) with an atypical chemokine receptor chem

35 ive leader cells with upregulated Delta-like ligand 4 (DLL4) expression as well as the role of NOTCH1

36 CXC-chemokine ligand 9 (CXCL9) is an interferon-inducible chemokine of

37 s two binding sites that compete for the cA4 ligand, a canonical cA4-activated ribonuclease activity

38 g the relative abundances of released glycan ligands according to their relative abundances in soluti

39 vestigated the binding to different putative ligands (acetylated BSA [AcBSA], zymosan, mannan, and LP

40 N are estimated for the first time using the ligand acidity constant (LAC) equation where contributio

41 lusters becomes more fragile and rigid after ligand addition.

42 ent structural relationships (e.g. distances ligand - amino acid).

43 the administration of a 50-mug total of CAIX ligand and 600-800 MBq of (99m)Tc-PHC-102.

44 (6) in the presence of a surface-stabilizing ligand and a high boiling point solvent to yield MoC(1-x

45 CD300LB, CD83, SIGLEC12, as well as the CD2 ligand and cell adhesion molecule CD58, all of which may

46 genes that encode Delta-like canonical Notch ligand and other secretory-specific transcription factor

47 de, iodoarenes, and alkenes using a JohnPhos ligand and potassium carbonate as a base in dimethylform

48 ecific ECs and other cell types by analyzing ligand and receptor expression patterns.

49 N,O-biaryl compounds that are widely used as ligands and catalysts.

50 omplexes are favored, stabilized by hydroxyl ligands and charge balancing calcium ions in the interla

51 groups which are suitable for attachment of ligands and high surface area), it was used in the struc

52 protein complexes and noncovalent binding of ligands and lipids to membrane proteins.

53 onic complexes containing strongly basic NHC ligands and noncoordinating anions such as BAr(F)(4) cat

54 fy essential elements of both the allosteric ligands and receptor binding sites important for these a

55 rm for understanding how strong trans effect ligands and redox-active ligands work together to enable

56 The relative efficiency of the three ligands and sense of stereoinduction for the most effici

57 irhodium-gear complexes with different axial ligands and that rotational barriers depend on their ste

58 lled by both the predetermined angles of the ligands and the mismatched structural tensions created f

59 the protein-ligand complex (amino acids and ligands) and the edges represent structural relationship

60 function of temperature, solvent, ancillary ligand, and arene substituent.

61 uthenium catalyst, does not require external ligands, and affords the desired products in > 99% NMR y

62 of iron complexes involving organophosphorus ligands applied in homogeneous catalyzed hydrometalation

63 e contributions to the pK(a)(MeCN) from each ligand are simply added together, with the sum corrected

64 ased catalyst supported by beta-diketiminate ligands are described.

65 Here we report that Slit ligands are expressed in overlapping and distinct patter

66 Interestingly, both l-glucose-derived ligands are partial agonists: they are among the least e

67 Conclusion: The (64)Cu-labeled PSMA ligands are promising agents to target PSMA and visualiz

68 Metal precursors and organic ligands are separated to reduce the kinetic reaction rat

69 a structural point of view, and new I(2)-IR ligands are urgently required for improving their pharma

70 Sulfur-based ligands are versatile donors that play important roles i

71 m HIV-1 TAR RNA and its interaction with the ligand argininamide (ARG), a mimic of TAR's cognate prot

72 same sequences and terminally sequenced nano-ligands at the same frequency independently facilitate f

73 The efficient ligand-based design approach adopted demonstrates its ve

74 ntification of DTMGM-SEGPHOS, a bisphosphine ligand bearing 3,5-bis(trimethylgermanyl)-4-methoxypheny

75 red to the wild type allele by measuring its ligand binding affinity, CCL2 scavenging efficiency, and

76 different binding sites and coupling between ligand binding and conformational change.

77 work provides unique tools to modulate aGPCR-ligand binding and establishes a foundation for the deve

78 lizing a recently established NanoBRET-based ligand binding assay.

79 tation did not affect surface expression and ligand binding but changed the susceptibility to heat de

80 ative splicing and retains the extracellular ligand binding domain but lacks the intracellular signal

81 Protein activity is often regulated by ligand binding or by post-translational modifications su

82 Structure-level analysis showed ligand binding pocket architectures differences in size,

83 ein originating in the peripheral C-terminal ligand binding site and culminating in pore opening.

84 regulated in this way often contain multiple ligand binding sites or modification sites, which can op

85 gating changes in the capacitance induced by ligand binding to the serotonin transporter and to the g

86 functional studies, but the determinants of ligand binding, selectivity, and signaling are still poo

87 unliganded wild-type TNFR1 but exhibited no ligand binding.

88 a general understanding of membrane-mediated ligand binding.

89 om site-directed mutagenesis and competitive ligand-binding analyses revealed that DPO and Ala-AA occ

90 rast, a form of TNFR1 with a mutation in the ligand-binding CRD2 subdomain retained the monomer-to-di

91 f the beta11-12 linker in the extracellular, ligand-binding domain is an integral component of the de

92 r study suggests the existence of an optimal ligand-binding pocket conformation for capsaicin-mediate

93 For MN4, ligand-binding results in the reduction of dynamics that

94 ir conformational flexibility, together with ligand-binding site and interaction mechanisms.

95 These calculations identified two potential ligand-binding sites.

96 oaches, we identified a novel quinoline core ligand, BMPQ-1, which bound to human telomeric G-quadrup

97 on, so the dataset contains a minimum of two ligand-bound and two ligand-free structures for each pro

98 s and Matthew's correlation coefficients for ligand-bound versus ligand-free structure performance sh

99 mechanism and activate T cells with solution ligands by cross-linking pMHC or using multivalent antib

100 tes, and that the discrimination between RNA ligands by E. coli ProQ and Hfq depends both on positive

101 on TiO(2) with the 4,4'-dipyridyl anchoring ligand can maintain the monomeric structure of catalyst

102 ion on KIR2DS1 and KIR3DL1 and their cognate ligands can be used to classify donors as KIR-advantageo

103 small amounts of the Ru complex with N-oxide ligands can significantly activate single-site Ru-based

104 and Ca(2+) dynamics revealed that the TRPV1 ligand capsaicin activated CaCCs.

105 hysically interacts with C-C motif chemokine ligand (CCL) 8 and synthesized a 16-mer peptide (BK1.1)

106 ing protection from HIV.IMPORTANCE CD40-CD40 ligand (CD40L) interaction is crucial for inducing effec

107 Dy(3+)-centered emission rather than by the ligand-centered bands, implying that Dy(3+) can be tuned

108 RPV1 activation gating, and reveals multiple ligand-channel interactions that stabilize this permissi

109 The metal-to-ligand charge transfer (MLCT) excited states of Ru polyp

110 In this work, we aim to link ligand chemical structures to MIEs for androgen receptor

111 Rather than single applications, ligand combinations could synergistically potentiate imm

112 the nodes represent entities of the protein-ligand complex (amino acids and ligands) and the edges r

113 seudorabies virus (PRV) RNA G-quadruplex and ligand complex, (ii) PRV DNA G-quadruplex, and (iii) an

114 ational state of existing Env constructs and ligand complexes used for high-resolution structures rec

115 le to extend frustration analysis to protein-ligand complexes.

116 review, we discuss multivalent nucleic acid-ligand conjugates in the context of the biological prote

117 Eph receptors (Eph) and their ephrin ligands control cell interactions during normal developm

118 e of oxidative addition of bromobenzene to a ligand-coordinated palladium center.

119 Real-space refinement from pre-existing ligand coordinates of 150 macrocycles resulted in occupa

120 There is also a small reduction in metal-ligand covalency and an attendant increase in the d(x(2)

121 of the d-orbitals and a high degree of metal-ligand covalency due to metal -> ligand pai-backdonation

122 nd HIV, the chemokine receptor CXCR4 and its ligand CXCL12 have been the subject of numerous structur

123 borane building blocks to the GRPR-selective ligand [d-Phe(6), beta-Ala(11), Ala(13), Nle(14)]Bn(6-14

124 The TGF-beta ligand DAF-7 likely acts upstream of IIS and links feedi

125 eylamine, even for unpurified PQDs with high ligand density.

126 A2 adopts two alternate conformations in the ligand-dependent and the ligand-independent states.

127 istic framework for therapeutic targeting of ligand-dependent Hh signaling in human cancers with soma

128 re that tamalin plays a critical role in the ligand-dependent internalization of mGluR1 and mGluR5, m

129 Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription regulator, containing two

130 ation of important compound classes, such as ligand derivatives and polyaromatics, and in the late-st

131 PFQX in conjunction with ligand-directed acyl imidazole chemistry enables covalen

132 Finally, we propose that RNA ligand discovery can benefit from using progress made wi

133 ility, understanding the processes governing ligand dynamics is of fundamental importance.

134 ppa Opioid Receptor (KOR) and its endogenous ligand dynorphin in mediating these processes.

135 and shell by so-called "exciton-delocalizing ligands (EDLs)" is a promising strategy to enhance coupl

136 ed on MHC binding or naturally processed MHC ligand elution data.

137 ach also demonstrates that efficient surface ligand engineering can exploit the unique electrochemica

138 sing a combination of ligand mutagenesis and ligand engineering.

139 Some Ni enzymes utilize special ligand environments for tuning the Ni(II)/(III) redox co

140 Na, Li) does not result in simple metathetic ligand exchange but entails disproportionation with form

141 f [bipy-Ru(III) Cl(4) ](-) with simultaneous ligand exchange from Cl(-) to CO.

142 L) implemented using 1,2-ethanedithiol (EDT) ligand exchange on top of the CQD active layer.

143 termined and investigated through a cycle of ligand-FEP calculations, validating the binding orientat

144 sence of SPRY1, FGF9, and FGF20, another FGF ligand, FGF8, promotes nephrogenesis.

145 rmazanate ligand, resulting in an "inverted" ligand field, with an approximate "two-over-three" split

146 affinity and selectivity, including limited ligand flexibility, as observed by ligand preorganizatio

147 t wavelength shift and an enhancement of the ligand fluorescence signal.

148 ining opening of the chelate by an ancillary ligand followed by additional chain walking allows the m

149 terobifunctional molecules consisting of one ligand for binding to a protein of interest (POI) and an

150 Pamoic acid is a potent ligand for G protein Coupled Receptor 35 (GPR35) and exh

151 refore, [(11)C]13 is a potential PET imaging ligand for mGluR2 in different central nervous system-re

152 of 68 mum), but LCA is also a highly potent ligand for TGR5 (EC(50) 0.52 mum).

153 is a large (> 60-amino-acid) natural peptide ligand for the ErbB protein family members HER3 and HER4

154 ed complex N-glycans, which serve as a major ligand for this lectin.

155 hesizing pharmaceuticals, agrochemicals, and ligands for metal complexes, but strategies to selective

156 Jacquemin et al., the authors reported that ligands for NKG2D are upregulated in vitiligo perilesion

157 grammed death ligand 1 (PD-L1) and PD-L2 are ligands for PD-1; the former is ubiquitously expressed i

158 Membrane-bound ligands for stimulation and co-stimulation of T-cell rec

159 lic acid and deoxycholic acid, the principal ligands for TGR5, are decreased in particular.

160 These lipids are endogenous ligands for the nuclear receptor PPARalpha, and we demon

161 ystal structures of two distinct isoforms of ligand-free human karyopherin RanBP5 and investigate its

162 elation coefficients for ligand-bound versus ligand-free structure performance show no statistically

163 ntains a minimum of two ligand-bound and two ligand-free structures for each protein.

164 Low nano-ligand frequency in the same sequences and terminally se

165 rk (TGN), is involved in the presentation of ligands from Mycobacterium tuberculosis (Mtb) to MAIT ce

166 iew, we discuss our current understanding of ligand-gated ion channel and G protein-coupled receptor

167 ptors (GlyRs) are anion-permeable pentameric ligand-gated ion channels (pLGICs).

168 Targeting receptor proteins, such as ligand-gated ion channels and G protein-coupled receptor

169 5-HT(3) receptors are pentameric ligand-gated ion channels that regulate synaptic activit

170 , which integrates complementary methods for ligand-GPCR interaction recognition and thus significant

171 However, the specific role played by each ligand has been unclear.

172 Accordingly, the ema ligand has switched its coordination mode from an N(2) S

173 iated and expressed high levels of the NKG2C ligand HLA-E.

174 of gene activation in response to microbial ligands; however, these studies do not reflect a compreh

175 pite concomitant degradation of the covalent ligand/Hsp90 complex.

176 understanding TIM3 biology, including novel ligand identification and the discovery of loss-of-funct

177 multiple criteria, e.g. metalloenzyme name, ligand identifier, functional class, bioinorganic class,

178 and humans, but the individual roles of its ligands, IL-17A, IL-17F, and IL-17AF, are less clear.

179 H(9) }(2) Li] 3Dy and show that dicarbollide ligands impose strong magnetic axiality on the central D

180 )CO(3) as the base and t-Bu(3)PHBF(4) as the ligand in DMSO at 120 degrees C in a sealed tube deliver

181 c elements as substrates as well as the Mo/W ligand in DMSORs has indelibly shaped the diversificatio

182 s the preferred oxidation state of the dioxo ligand in this complex.

183 RROUNDING REGION (ESR)-RELATED (CLE) peptide ligands in connection with their receptors are important

184 lective covalent attachment of electrophilic ligands in eubacterial TGTs.

185 Toll-like receptor ligands in indoor dust act as environmental adjuvants to

186 the considerable potential of isonitriles as ligands in metal catalysis utilizing both commercially a

187 However, the role and fate of the oxide ligands in such intriguing additional capacity remain un

188 imulated human macrophages in vitro with TLR ligands in the presence of high-density immune complexes

189 hines is more scattered, but the most common ligands include BINAP, Me-Duphos, Josiphos, and related

190 of established and newly identified cohesin ligands, including the cohesin release factor WAPL(2,3).

191 iptional regulation of tankyrase serves as a ligand-independent developmental mechanism for post-tran

192 TrkB.T1 in the PI3K signaling cascades in a ligand-independent fashion.

193 rning of the embryo, is dispensable for both ligand-independent signaling pathway activation and liga

194 onformations in the ligand-dependent and the ligand-independent states.

195 These results underscore the importance of ligand-independent TNFR1 dimerization in NF-kappaB signa

196 ependent of the initial configuration of the ligand, indicating the ability of the 18-membered P(4)N(

197 In contrast, ligand-induced corepressor-dependent NR repression appea

198 In the last decade voltage modulation of ligand-induced GPCR activity has been reported for sever

199 The glycan ligand information is displayed, and links are provided

200 Semaphorin ligands interact with plexin receptors to contribute to

201 nge of future applications including protein-ligand interaction studies as well as qualitative and qu

202 mediators of adaptive immunity, and receptor-ligand interactions that regulate their survival may hav

203 s an abstract model for representing protein-ligand interactions.

204 sed strategy to detect motifs at the protein-ligand interface with an interactive platform to visuall

205 rpret these motifs in the context of protein-ligand interfaces.

206 For example, Fas ligand is commonly overexpressed in TMEs and induces apo

207 During cochlear development, the Notch ligand JAGGED 1 (JAG1) plays an important role in the sp

208 the expression of Notch 1-4 receptors, their ligands (Jagged 1-2, DLL1,3,4), gamma-secretase complex

209 speptin receptor, Kiss1r (Kiss1r-/-) and its ligand kisspeptin, Kiss1 (Kiss1-/-) replicate the phenot

210 nt a pyrazolate-based bis(beta-diketiminato) ligand [L(Ph)](3-) with bulky m-terphenyl substituents t

211 ive rationally designed low-molecular-weight ligands (L1-L5) were synthesized using the lysine-urea-g

212 otif, we identified over 70 putative SNX-BAR ligands, many of which play critical roles in apoptosis,

213 ion suggests that functionally redundant FGF ligands may contribute to vestibular hair cell different

214 n mammals, anandamide, as an endocannabinoid ligand, mediates several neurological and physiological

215 um-derived stromal cells (EpiSC) by specific ligands might enable the direct imaging of EpiSCs after

216 This ligand mimetic design and optimization approach can be e

217 ingful insights into their interactions with ligand molecules.

218 o-receptors for RSPO3 using a combination of ligand mutagenesis and ligand engineering.

219 allow synthesis of unlimited combinations of ligand nano-sequences and frequencies, magnetic elements

220 The influence of dispersion interactions on ligand-nanoparticle binding is also explored, by establi

221 ed in neurons and signals in response to two ligands, NGF and neurotrophin-3 (NT-3), with very differ

222 o the gut is mediated by MAdCAM, the natural ligand of alpha(4)beta(7) that is expressed on gut endot

223 ly remove both long-chain insulating surface ligands of oleic acid and oleylamine, even for unpurifie

224 were predicted based on sequence signatures, ligands of shorter sequences have not been identified, t

225 Protein ligands of the flavin mononucleotide (FMN) and the plant

226 ied to the biaryl backbone of a bisphosphine ligand on the rate of oxidative addition of bromobenzene

227 for signal transduction and whether a native ligand or other activating input is required.

228 ts to a high receptor activator of NF-kappaB ligand/osteoprotegerin (RANKL/OPG) ratio as the primary

229 ee of metal-ligand covalency due to metal -> ligand pai-backdonation.

230 ntramolecular hydrogen bonds within pyrazine ligands, pai-interactions, coordination to metal ions, a

231 that induced by toll-like receptor 2 (TLR2) ligand Pam3Cys, but different from those induced by the

232 dation of SUPPRESSOR OF MAX2 1 (SMAX1) after ligand perception is considered to be a key step in KAR/

233 nds that have partial coverage of the target ligand, performs conformational sampling and template-gu

234 receptor activator of unclear factor kappa-B ligand, periostin, and peroxidasin gene expressions in p

235 These results suggest that Notch ligands play specific roles in the adult pancreas and hi

236 toring allow us to propose that the pyridone ligand plays a role in enhancing the rate- and enantio-d

237 g limited ligand flexibility, as observed by ligand preorganization and 3D shape complementarity for

238 Diverse NF-kappaB-activating ligands produced different patterns of RelA and c-Rel si

239 ge of MAGELLAN is attributed to the power of ligand profiling, which integrates complementary methods

240 r the most efficient diether and amino ether ligands prove to be foreseeable by modeling the reaction

241 Additionally, we unravel a unique ligand rearrangement for these classes of anionic mesoio

242 receptor-6 (DR6) on MNs as the top predicted ligand-receptor pair.

243 s to be a challenging endeavor and efficient ligand-receptor systems need to be identified.

244 n the DUX4 locus and that the GQ interactive ligand reduces DUX4 expression suggesting potential role

245 PqqE variants with nondestructive ligand replacements at AuxII also show that the reductio

246 can generate the peptide- and protein-based ligands required to study them.

247 reveal the molecular interactions governing ligand residence time.

248 Variation of key ligand residues within the short sequence was undertaken

249 r cell death in presence or absence of their ligand, respectively.

250 ng interferon-gamma, interleukin-2, and CD40 ligand) responses were evaluated at month 6.5 for all pa

251 independent signaling pathway activation and ligand-responsive signaling hyperactivation by ACVR1-R20

252 mbination therapy with CD40 agonist and Flt3 ligand restores cDC1 abundance to normal levels, decreas

253 e pai-acceptor properties of the formazanate ligand, resulting in an "inverted" ligand field, with an

254 l and Mincle or blockade of their endogenous ligand SAP130 revealed that these receptors' expression

255 We also investigated how preventing Wnt ligand secretion from endothelial cells affects zonation

256 Accordingly, tropomyosin "ligand" segments were rotated and translated over potent

257 ecule likely targets the receptor complex in ligand-selective modes.

258 was co-integrated, reflecting an increase in ligand sensitivity and a decrease in limit of detection

259 interface of the inorganic core and organic ligand shell by so-called "exciton-delocalizing ligands

260 Intriguingly, we show that the ligand shell of Au(25) nanoclusters becomes more fragile

261 Ligand similarity analysis suggests that only module 6R

262 tions only over a finite range of prescribed ligand source/sink ratios where the model ocean is drive

263 Upon ligand stimulation, the endoplasmic reticulum (ER) prote

264 nd its receptors or major chemokine receptor-ligand subsets persisted in the long term.

265 electronically and structurally similar EDO ligands such as dimethyl fumarate and electron-deficient

266 The ubiquity of phospho-ligands suggests that phosphate binding emerged at the e

267 HDL NPs are a cholesterol-poor ligand that binds to the receptor for cholesterol-rich H

268 udy, we show that Wnt5A, a non-canonical Wnt ligand that drives a metastatic, therapy-resistant pheno

269 the substituents on the phosphorus, as a new ligand that forms a highly active catalyst for hydrobora

270 ification of a highly selective G-quadruplex ligand that, when studied in human cancer cells, proved

271 It searches for known complexes with ligands that have partial coverage of the target ligand,

272 enables a reaction between NH(3) and the Cl ligands that produces HCl.

273 Supported by a beta-diketiminate ligand, the three-coordinate copper(II) alkynyl [Cu(II)]

274 The lack of an effect of ligands, the formation of carbon-centered radicals with

275 gnition of sialic acid-containing glycans as ligands, they help the immune system distinguish between

276 le PTP inhibitor with an E3 ligase targeting ligand through a well-designed linker, the first molecul

277 eus or mitochondria can also serve as a cGAS ligand to activate this pathway and trigger extensive in

278 We used G-quadruplex-stabilizing ligand to define the inhibition in LANA expression and p

279 ry, allows the relative affinities of glycan ligands to be ranked.

280 substituents on the cyclopropanecarboxylate ligands to have well-defined sterically demanding cataly

281 requencies, magnetic elements, and bioactive ligands to remotely regulate numerous host cells in vivo

282 solvents are commonly employed as ancillary ligands to stabilize late transition metal complexes and

283 s by dynamic encapsulation and high-affinity ligands to target the construct to specific neuronal cel

284 plexant together with 2,2'-bipyridine as the ligand took place only with PhI at 50/70 degrees C.

285 ion of its Robo3 affinity and is enhanced by ligand trimerization.

286 This site sequesters apolar ligands via a concave hydrophobic surface in SAA oligome

287 s accessible by employing chiral phosphorous ligands was obtained.

288 properties of monovalent and heterobivalent ligands were characterized in 5-HT(2A)-, mGlu(2)/Gqo5-,

289 Although many ligands were predicted based on sequence signatures, lig

290 approach led to the discovery of this novel ligand, which was successfully applied in the preparatio

291 nding platform for 21 amino acid CIF peptide ligands, which are tyrosine sulfated by the tyrosylprote

292 simulations of (un)binding pathways of TSPO ligands, which could reveal the molecular interactions g

293 As over 99% of iron is complexed to organic ligands, which increase iron solubility and microbial av

294 predicted endogenous HLA class I-associated ligands with 1.5-fold improvement in positive predictive

295 Concurrently, the preparation of AMPP* ligands with a P-chirogenic phosphinite moiety was perfo

296 mpound 5 represents a new class of selective ligands with antileishmanial activity.

297 n the malaria parasite, interaction data for ligands with antimalarial activity, and establishes cura

298 esign to develop more subtype-selective GPCR ligands with potentially reduced side effects and provid

299 II and class II-III bis(dioxolene) bridging ligands with sufficiently weak intramolecular coupling.

300 strong trans effect ligands and redox-active ligands work together to enable rapid electrochemical CO