ライフサイエンスコーパス: ligand-dependent

1 that EGFR-induced vemurafenib resistance is ligand dependent.

2 the Shh response in Ptch1(-/-) cells remains ligand dependent.

3 ed in urothelial carcinoma cell lines was HH ligand dependent.

4 ctivity of transmetalation and reactivity is ligand dependent.

5 stal residues involved in GSH binding and is ligand dependent.

6 strate that LRP1-initiated cell signaling is ligand-dependent.

7 and 10 rate constants, only two of which are ligand-dependent.

8 erally, our study provides insights into the ligand-dependent AA2AR activation/deactivation in additi

9 ent Structure (SiM-KARTS) to investigate the ligand-dependent accessibility of the SD sequence of an

10 inding, such that DAs generate a signal upon ligand-dependent ACE-aptamer dehybridization.

11 Here we demonstrate that ligand-dependent action of the orphan RORgamma can be de

12 In addition to ligand-dependent activation and concomitant tyrosine pho

13 These findings contrast with ligand-dependent activation and coupling to mammalian ta

14 f N-glycans at Asn-247 by sialic acid, tunes ligand-dependent activation and signaling of VEGFR2 in e

15 , TRPV6, do not exhibit thermosensitivity or ligand-dependent activation but are constitutively open

16 interact with the ligand-independent and the ligand-dependent activation domains of estrogen receptor

17 For most nuclear receptors, the ligand-dependent activation function domain-2 (AF-2) is

18 This protein showed robust, ligand-dependent activation in prokaryotic and eukaryoti

19 element of the switch in this RNA, supported ligand-dependent activation of a reporter gene over a br

20 Ligand-dependent activation of Crth2 by 13,14-dihydro-15

21 Ligand-dependent activation of Hedgehog (Hh) signaling i

22 ression directed both ligand-independent and ligand-dependent activation of NFkappaB, mediated by a s

23 vely, independently of a requirement for the ligand-dependent activation of RXRalpha.

24 The latter is the case in which Slit2 ligand-dependent activation of the blood vessel endothel

25 role of Ca(2+)/CaM in the regulation of the ligand-dependent activation of the epidermal growth fact

26 we discuss the functional evidence regarding ligand-dependent activation of TRPV1 channels in light o

27 Ligand-dependent activation, gamma-secretase-processed c

28 g the structural basis of channel gating and ligand-dependent activation.

29 ith significant inter-species differences in ligand-dependent activation.

30 To elucidate the ligand-dependent activation/deactivation mechanism of th

31 d the molecular and structural bases for its ligand-dependent activation; this was achieved by identi

32 ly of activators, functions principally as a ligand-dependent activator of promoter clearance.

33 orphan NRs) and it's unclear if they possess ligand dependent activities.

34 Ligand-dependent activity has been engineered into enzym

35 In many diseases, expression and ligand-dependent activity of the p75(NTR) receptor can p

36 tioning both as a transcription factor and a ligand-dependent adaptor in an ubiquitin ligase complex.

37 eriments reveal that FnBPA exhibits bimodal, ligand-dependent adhesive behavior.

38 several of these residues are important for ligand-dependent AhR activation, and their mutation resu

39 on enhancers serve as determinants of rapid ligand-dependent alterations in chromosomal architecture

40 Comparative analysis of ligand-dependent alternating access in LeuT and Mhp1 lea

41 nserved residues to illuminate principles of ligand-dependent alternating access of PfMATE, a proton-

42 DREADD activation produced a ligand-dependent analgesia to heat in vivo and a decreas

43 -coupled) DREADD in nociceptors might enable ligand-dependent analgesia.

44 nsactivation of the AR/AR-V7 target genes in ligand dependent and independent manners respectively.

45 gnaling in tissue-resident macrophages, both ligand dependent and independent, limited HIV-1 replicat

46 Ligand-dependent and -independent AR signaling mediated

47 ing (NB) domains that regulate both effector ligand-dependent and -independent cell death signaling a

48 ctive oxygen species (ROS) and involves both ligand-dependent and -independent mechanisms, but the pr

49 invasive cellular effects via both EphrinB2 ligand-dependent and independent mechanisms.

50 Both ligand-dependent and ligand-independent activities are e

51 owth factor receptor (EGFR) and enhances its ligand-dependent and ligand-independent activity.

52 androgen receptor and strongly enhance both ligand-dependent and ligand-independent androgen-recepto

53 ancy, leading ultimately to a suppression of ligand-dependent and ligand-independent AR residence on

54 ment of a variety of organ systems, and both ligand-dependent and ligand-independent Hh pathway activ

55 s a purely antagonistic antibody that blocks ligand-dependent and ligand-independent Met signaling by

56 pshift was associated with increases in both ligand-dependent and ligand-independent PR phosphorylati

57 different TM crossing angles, resembling the ligand-dependent and ligand-independent states.

58 r endocytosis and lysosomal degradation in a ligand-dependent and receptor kinase activity-dependent

59 ional changes in the clamp region of RyR are ligand-dependent and suggest the existence of multiple l

60 A2 adopts two alternate conformations in the ligand-dependent and the ligand-independent states.

61 sting opposite roles of EphA3 on inhibiting (ligand-dependent) and promoting (receptor processing) ax

62 These reactivities were found to be ligand-dependent, and a trend could be established.

63 Sumoylation of TRbeta was ligand-dependent, and sumoylation of TRalpha was ligand-

64 Although previous studies have focused on ligand-dependent AR signaling, in this study we explore

65 of FoxA1, a transcription factor involved in ligand-dependent AR targeting.

66 A key step in JA signaling is ligand-dependent assembly of a coreceptor complex consis

67 Unexpectedly, while acute ligand-dependent assembly of eRNPs resulted in enhancer

68 sion of discovered variants demonstrated non-ligand-dependent auto-phosphorylation, responsive to the

69 a subtypes, ligand-independent ('tonic') and ligand-dependent BCR signaling have been characterized,

70 ein pathways and beta-arrestin pathways; the ligand-dependent bifurcation of such signaling is referr

71 oparticles were optimized and NTCP-specific, ligand-dependent binding and internalization was confirm

72 tery scheme to clarify how an extracellular (ligand-dependent) binding event activates the intracellu

73 ese results indicate that the oncogenic role ligand-dependent BMP signaling plays in suppressing diff

74 These data uncover a ligand-dependent, but gamma-secretase-independent, non-c

75 or LRP6 is overexpressed, signaling remains ligand-dependent, but the requirement for both receptors

76 we tested the hypothesis that it influences ligand-dependent Ca(2+) release.

77 d be explored to treat patients harboring HH ligand-dependent cancers.

78 stant to ectodomain shedding, inhibited RAGE ligand dependent cell signaling, actin cytoskeleton reor

79 We report here that neuritogenesis-promoting ligand-dependent cell surface clustering of CHL1 induces

80 amics define the functional behavior of this ligand-dependent channel.

81 scale faster than the greatest difference in ligand-dependent chemical shift (i.e. >100 Hz).

82 The ligand-dependent competing actions of nuclear receptor (

83 es, evaluate protein structure, and identify ligand dependent conformational changes in proteins are

84 A ligand-dependent conformational change is thought to reg

85 in nanodiscs undergoes functionally relevant ligand-dependent conformational changes and that previou

86 The observed ligand-dependent conformational changes in KirBac1.1 pro

87 ignals provided evidence of redox-state- and ligand-dependent conformational changes localized near t

88 These ligand-dependent conformational changes suggest a potent

89 ) undergoes modest redox-state-dependent and ligand-dependent conformational changes.

90 ues and x-ray crystallography to examine the ligand-dependent conformational dynamics of CYP119.

91 investigated how these structures relate to ligand-dependent conformational dynamics of MdfA in lipi

92 tudy the structural features involved in the ligand-dependent conformational heterogeneity of GPCRs b

93 ables transcription intermediates to undergo ligand-dependent conformational refolding.

94 l pH levels, and they fail to undergo pH- or ligand-dependent conformational switching.

95 Ligand-dependent control of gene expression is essential

96 sensor protein RsbR binds haem and exhibits ligand-dependent control of the stressosome complex acti

97 etic pathway in a single step and showed the ligand-dependent coordinated expression of all five gene

98 idely expressed transcriptional coregulator, ligand-dependent corepressor (LCoR), initially character

99 In line with this, progressive decrease of ligand-dependent corepressor expression was observed in

100 nd that stromally-secreted activin A induced ligand-dependent CRC epithelial cell migration and epith

101 ession is controlled with near-IR light in a ligand-dependent CreER(T)/LoxP-reporter cell line derive

102 Binding of beta-arrestin1 to IGF-1R leads to ligand-dependent degradation of the receptor and generat

103 Ligand-dependent differences in the regulation and inter

104 This arrangement suggests a potential ligand-dependent dimerization mechanism for TCR signalin

105 Upon the ligand-dependent dimerization of the epidermal growth fa

106 ty of activation mechanisms, often involving ligand-dependent dimerization or conformational changes.

107 urine AhR and ARNT proteins was designed and ligand-dependent DNA binding ability of the AhR:ARNT het

108 cases such as docking to homology models and ligand dependent domain rearrangements.

109 conditioning and allogeneic BMT, induce PD-1 ligand-dependent donor nTreg proliferation, and maintain

110 urface proteins, we observed significant PDZ ligand-dependent EAAT2b surface expression in cultured a

111 talloprotease ADAM10/Kuzbanian catalyzes the ligand-dependent ectodomain shedding of Notch receptors

112 ing a new single-vector strategy that allows ligand-dependent, efficient removal of a gene of interes

113 by wound-derived signals such as ATP, direct ligand-dependent EGFR activation primarily involves NOX2

114 ading cells with a Ca(2+) chelator inhibited ligand-dependent EGFR auto(trans)phosphorylation.

115 TMEM16A up-regulation is associated with the ligand-dependent EGFR signaling pathway.

116 gistic and antagonistic interactions between ligand-dependent EGFRwt and EGFRvIII signaling.

117 for FLS2 and reveal a defined framework for ligand-dependent endocytosis of this receptor.

118 as inhibition of degranulation was OX40/OX40 ligand dependent, enhancement of IL-6 was due to TGF-bet

119 Condensins positively regulate ligand-dependent enhancer activation at least in part by

120 nexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicki

121 a (ERalpha) to define two distinct phases of ligand-dependent enhancer formation.

122 ne kinase, PDGFRbeta, which facilitates PDGF ligand-dependent, ephrin ligand-independent activation o

123 y, recombination was detected in many FGFR2b ligand-dependent epithelia.

124 anscription factors significantly influences ligand-dependent, ER-driven transcriptional responses, a

125 region contains a previously uncharacterized ligand-dependent ERalpha binding function, indicating ho

126 ystem was devised that enables quantitative, ligand-dependent exponential amplification for various l

127 D and L reaction systems undergo isothermal, ligand-dependent exponential amplification in the same m

128 This interaction required ligand-dependent exposure of a TCF binding region that m

129 teract with the glucocorticoid receptor in a ligand-dependent fashion and globally alter the transcri

130 to modify the output of other receptors in a ligand-dependent fashion may be a general principle for

131 ptor and regulatory domains communicate in a ligand-dependent fashion to regulate mRNA expression.

132 y interact with the APC/C(Cdh1) complex in a ligand-dependent fashion without being targeted for prot

133 ion allows the protein to interconvert, in a ligand-dependent fashion, between two mutually exclusive

134 OSTbeta organic solute transporter loci in a ligand-dependent fashion.

135 pump (BSEP)] promoter reporter activity in a ligand-dependent fashion.

136 all, these data reveal an essential role for ligand-dependent feedback inhibition of vertebrate HH si

137 ches of the same class that exhibit strictly ligand-dependent folding.

138 The present data suggest that ligand-dependent formation of HMGA1-Ubc9-PPARgamma compl

139 ational changes compatible with thermal- and ligand-dependent gating.

140 ptors (NRs), which play an important role in ligand-dependent gene expression and human health.

141 Flt3 ligand-dependent generation of CD8alpha(+) cDCs in lymph

142 This occurred via a ligand-dependent, genotype-independent mechanism accordi

143 However, complete details of ligand-dependent GPCR activation/deactivation are diffic

144 revealing distinct structural mechanisms for ligand-dependent GPCR function.

145 rodimeric nuclear receptors can also mediate ligand-dependent HBV transcription and replication when

146 luable probe for investigating and targeting ligand-dependent hedgehog pathway activation in cancer a

147 istic framework for therapeutic targeting of ligand-dependent Hh signaling in human cancers with soma

148 In particular, the existence of autocrine, ligand-dependent Hh signaling in SCLC has been disputed.

149 Taken together, our data show that ligand-dependent homotypic interactions in D5 and D7 are

150 teric binding site by which Nb6 stabilizes a ligand-dependent inactive state.

151 pharmacological characterization indicated a ligand-dependent increase in intracellular calcium in 13

152 athway in isolated mouse VSMCs revealed CD36 ligand-dependent induction of Fyn phosphorylation, with

153 ry early in glia and in pericytes to mediate ligand-dependent induction of inflammatory cytokines, di

154 that p75NTR in glia and in pericytes mediate ligand-dependent induction of inflammatory cytokines, di

155 em to exert important roles for the observed ligand-dependent induction of target coding genes, incre

156 This dynamic and ligand-dependent interaction with chromatin is likely sh

157 Our main purpose was to investigate the ligand-dependent interactions of Alt a 1 in the human ai

158 the binding site residues gain different and ligand-dependent interactions that could not be predicte

159 re that tamalin plays a critical role in the ligand-dependent internalization of mGluR1 and mGluR5, m

160 nockdown of endogenous tamalin inhibited the ligand-dependent internalization of these two receptors.

161 us convergent regulatory mechanisms of these ligand-dependent ion channels.

162 were more sensitive to Ca-dependent and Fas ligand-dependent killing by cytotoxic T lymphocytes.

163 n protein X-ray crystallographic structures, ligand-dependent LBD stabilization assays, and cell-base

164 tering enhances valency and further promotes ligand-dependent LFA-1 activation.

165 anscriptionally by the androgen pathway in a ligand-dependent manner and is further enhanced by the h

166 phrin receptor EphB2 can form a complex in a ligand-dependent manner and that Netrin-ephrin synergist

167 its ability to interact with PDGFRbeta in a ligand-dependent manner and to promote its downstream JN

168 omers and if these species interconvert in a ligand-dependent manner are among the most contentious c

169 receptor 2 (DR5) forms receptor dimers in a ligand-dependent manner at endogenous receptor levels, a

170 ter assay findings suggest that PR acts in a ligand-dependent manner through binding to two progester

171 d that STAT5 is recruited to the IL-25R in a ligand-dependent manner through unique tyrosine residues

172 e ANTH and ENTH domains bind each other in a ligand-dependent manner to provide critical anchoring of

173 we demonstrate that G-proteins modulate in a ligand-dependent manner two fundamental cell-polarity be

174 corepressor complexes, which associate in a ligand-dependent manner with FXR, and increased FXR bind

175 D3) cells, Dragon generated BMP signals in a ligand-dependent manner, and BMP4 is the predominant end

176 ansmits this conformational plasticity, in a ligand-dependent manner, to a phenylalanine residue (Phe

177 Importantly, ARGLU1 is recruited, in a ligand-dependent manner, to endogenous estrogen receptor

178 ype in an inducible costimulator (ICOS)/ICOS ligand-dependent manner.

179 FAM150A stimulates LTK phosphorylation in a ligand-dependent manner.

180 ventitial lymphatic EC (LEC) population in a ligand-dependent manner.

181 nterface for binding signaling partners in a ligand-dependent manner.

182 d vaginal epithelial cell proliferation in a ligand-dependent manner.

183 lls and induced their apoptosis in a Fas/Fas ligand-dependent manner.

184 olonocytes blocks TNF-induced apoptosis in a ligand-dependent manner.

185 n among different conformational states in a ligand-dependent manner.

186 ation through phosphorylation of AtRGS1 in a ligand-dependent manner.

187 the average microvillar velocity varies in a ligand-dependent manner; that catch bonds generate respo

188 In cancer, ErbB3 activation is driven by a ligand-dependent mechanism through the formation of hete

189 th via activation of Caspase-8 through a Fas ligand-dependent mechanism.

190 nergic P2Y(2) receptor stimulation, and both ligand-dependent mechanisms as well as ligand-independen

191 n cell migration assays indicated that Gal-1 ligand-dependent melanoma cell migration was severely in

192 Ligand-dependent Mer or Axl activation stimulated MAPK,

193 ompeted with HGF for MET binding, inhibiting ligand-dependent MET activity, downregulated cell surfac

194 ependent negative feedback potently suppress ligand-dependent mitogenic signaling and Ras function.

195 lts provide strong support for an autocrine, ligand-dependent model of Hh signaling in SCLC pathogene

196 nic cation transporter (rOct1), voltage- and ligand-dependent movements of fluorescence-labeled cyste

197 membranes is an important element in tuning ligand-dependent Notch signalling in different physiolog

198 Induction of autophagy required ligand-dependent, Notch intracellular domain (NIC) activ

199 Rev-erbalpha is a ligand-dependent nuclear receptor and a key repressor of

200 Estrogen receptor alpha (ERalpha) is a ligand-dependent nuclear receptor that is important in b

201 ceptors Lxralpha/NR1H3 and Lxrbeta/NR1H2 are ligand-dependent nuclear receptors critical for midbrain

202 A ligand-dependent nuclear transcription factor, ERalpha h

203 Using modified ERalpha to assay ligand-dependent nuclear translocation, we observed D3-d

204 We found that NAIP proteins control ligand-dependent oligomerization of NLRC4 and that the N

205 Ligand-dependent oligomerization of receptor tyrosine ki

206 nique allosteric mechanism for inhibition of ligand-dependent or ligand-independent ErbB3-driven canc

207 ecules are responsible for regulating normal ligand-dependent or oncogenic RTK activation via a "zipp

208 The long distance, ligand-dependent ordering of residues reveals new elemen

209 receptor activator of nuclear factor kappaB ligand-dependent osteoclast differentiation and MMP-9 se

210 s are not required for ligand-independent or ligand-dependent p75(NTR) activation in a growth cone re

211 ants) and therefore are completely devoid of ligand-dependent pathway activation.

212 or both perforin/granzyme as well as Fas/Fas ligand-dependent pathways of killing by NK cells.

213 receptor (AhR) is a conserved, environmental ligand-dependent, per ARNT-sim (PAS) domain containing b

214 ransfected with the human EGFR decreased its ligand-dependent phosphorylation.

215 The emerging structural insight reveals that ligand-dependent physiological activation is an outside-

216 ecognized conformational switch accompanying ligand-dependent PPARdelta transcriptional regulation.

217 In adipocytes, ligand-dependent PPARgamma activation is associated with

218 -independent activity, whereas AF-2 mediates ligand-dependent PR activation.

219 Both constitutive and ligand-dependent pre-BCR activation modes have been desc

220 By imaging ligand-dependent preQ1 riboswitch folding from multiple

221 fundamentally different from solution-phase, ligand-dependent processes.

222 Ligand-dependent proteolysis at the S2 site removes the

223 nished transcriptional function and exhibits ligand-dependent proteotoxicity, features that have both

224 on about the molecular mechanisms underlying ligand-dependent receptor activation is beginning to eme

225 logy to more accurately describe and predict ligand-dependent receptor activity.

226 Fuc-TVII(-/-) mice, indicating that selectin ligand-dependent recruitment of monocytes is required fo

227 sence of Slitrk5, TrkB has a reduced rate of ligand-dependent recycling and altered responsiveness to

228 K2 activities, indicating an endogenous, non-ligand-dependent regulation of PXR and CYP3A4, possibly

229 Ligand-dependent regulation of the channel activity is a

230 ctural elements that contribute to efficient ligand-dependent regulatory activity in a co-transcripti

231 Removing FL or FGF2 from ligand-dependent resistant cultures transiently restored

232 endent and suggest the existence of multiple ligand dependent RyR activation mechanisms associated wi

233 BM progenitors, supporting a requirement for ligand-dependent selection, as is the case for normal B1

234 e glmS ribozyme riboswitch, which performs a ligand-dependent self-cleavage reaction.

235 Aptazymes are small, ligand-dependent self-cleaving ribozymes that function i

236 from L-ribonucleotides, was shown to undergo ligand-dependent, self-sustained replication with expone

237 ions of which depended on ligand, whereas no ligand-dependent shifts were observed, consistent with t

238 logically important pleiotropic coupling and ligand-dependent signal bias.

239 f of ERK-dependent feedback, reactivation of ligand-dependent signal transduction, increased Ras-GTP,

240 l for IRAK4 autophosphorylation in vitro and ligand-dependent signaling in cells.

241 harmacologically characterized and exhibited ligand-dependent signaling, internalization, and wild-ty

242 de RNAi screen to identify genes involved in ligand-dependent signaling, we unexpectedly identified t

243 erexpression and amplification show enhanced ligand-dependent signaling, with increased activation of

244 s define rules guiding how NRs integrate two ligand-dependent signalling pathways into RXR heterodime

245 yet the molecular mechanisms responsible for ligand-dependent signalling responses remain poorly unde

246 ngs provide a model system for investigating ligand-dependent signalling within stressosome complexes

247 id X receptor (RXR), allowing integration of ligand-dependent signals across the dimer interface via

248 in vitro and in vivo work that demonstrated ligand-dependent species differences in AHR1 affinity.

249 This ligand-dependent stabilization of rate-defining conforma

250 duction of endogenous miR-9 expression, upon ligand-dependent stimulation of PDGFRbeta signaling, pro

251 Ligand-dependent SUMOylation of farnesoid X receptor (FX

252 Ligand-dependent SUMOylation of liver X receptors (LXRs)

253 ism may help in development of induced NKG2D ligand-dependent T-cell therapy against cancers.

254 We devised a chemical strategy that promotes ligand-dependent target protein degradation using as an

255 investigating this aspect of RNA folding as ligand-dependent termination is obligatorily co-transcri

256 While MR1 egress to the cell surface is ligand-dependent, the ability of small-molecule ligands

257 ere PKA-mediated Ser-2152 phosphorylation is ligand-dependent, the P2204L mutant is readily accessibl

258 s, CORM-2 inhibited endogenous and exogenous ligand-dependent TLR4 activation, which indicates that C

259 reveal a linkage between eRNA synthesis and ligand-dependent TOP1-mediated nicking-a strategy exerti

260 n in the androgen receptor, which results in ligand-dependent toxicity.

261 ERalpha has a ligand-dependent transactivation function in the ligand

262 s functional inactivation and attenuation of ligand-dependent transactivation.

263 Expression of Sumo1 markedly inhibited the ligand-dependent, transactivation of BSEP and SHP promot

264 Ligand-dependent transcription by the nuclear receptor g

265 The Ah receptor (AhR) is a ligand-dependent transcription factor belonging to the b

266 aryl hydrocarbon receptor (AhR), which is a ligand-dependent transcription factor belonging to the s

267 Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription factor containing two tra

268 The estrogen receptor (ER) is a ligand-dependent transcription factor containing two tra

269 or-activated receptor delta (PPARdelta) is a ligand-dependent transcription factor involved in fatty

270 iated by the glucocorticoid receptor (GR), a ligand-dependent transcription factor of the nuclear rec

271 (GRIP1), function as coactivators for GR, a ligand-dependent transcription factor of the nuclear rec

272 The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that binds to xeno

273 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that can be activa

274 Glucocorticoid receptor (GR) is a ligand-dependent transcription factor that can promote a

275 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that regulates exp

276 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor whose activity is

277 GC signal through the GC receptor (GR), a ligand-dependent transcription factor whose structure, D

278 ngly, the aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor with an emerging r

279 antitative assays for the activation of this ligand-dependent transcription factor.

280 ugh a nuclear receptor, which functions as a ligand-dependent transcription factor.

281 At the molecular level, ERs function as ligand-dependent transcription factors and activate targ

282 ligands may switch DNA motifs recognized by ligand-dependent transcription factors in vivo.

283 proliferator-activated receptors (PPARs) are ligand-dependent transcription factors regulating lipid

284 Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate most

285 such as the glucocorticoid receptor (GR) are ligand-dependent transcription factors that mediate tran

286 Steroid hormone receptors are ligand-dependent transcription factors that require the

287 s a member of the nuclear receptor family of ligand-dependent transcription factors, the main action

288 ember of the nuclear receptor superfamily of ligand-dependent transcription factors.

289 gamma, thereby solidifying their function as ligand-dependent transcription factors.

290 t for the design of allosteric modulators of ligand-dependent transcription factors.

291 Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription regulator, containing two

292 boswitches have been constructed to regulate ligand-dependent transcription termination in Escherichi

293 tutes a repressive barrier to the process of ligand-dependent transcriptional activity of nuclear rec

294 include castration modalities that suppress ligand-dependent transcriptional activity of the androge

295 ion is emerging as an important regulator of ligand-dependent transmembrane signaling, but precisely

296 Interestingly, crystallographic studies of ligand-dependent TRPV2 gating have shown that the TRPV2

297 GFR ligands and has potential for use in EGF ligand-dependent tumours.

298 ine-phosphorylated GIV in vitro and inhibits ligand-dependent tyrosine phosphorylation of GIV downstr

299 y a fibroblast-specific promoter, leading to ligand-dependent up-regulation of TGFbeta signaling, and

300 Ligand-dependent Y504 phosphorylation modulates the EphB