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1 rised a two-gene operon located on the 49-kb linear plasmid.
2 ith B. burgdorferi N40 DNA on a single 48-kb linear plasmid.
3 bha128, a 453-nucleotide gene of the 175-kb linear plasmid.
4 the 9.0-kb circular plasmid and the 27.5-kb linear plasmid.
5 B. hermsii had a 180-kb circular instead of linear plasmid.
6 of Escherichia coli known to lysogenize as a linear plasmid.
7 rmed 'pJAZZ' vector) that is maintained as a linear plasmid.
8 t Borrelia burgdorferi is located in a 54-kb linear plasmid.
9 BHA007 protein, which is encoded by a 174-kb linear plasmid.
10 This new element was demonstrated to be a linear plasmid.
11 d either a 90-kb (pCSL1) or a 140-kb (pCSL2) linear plasmid.
12 cent DNA rearrangement among a number of the linear plasmids.
13 ceeds much faster with supercoiled than with linear plasmids.
14 subfamilies were sequenced and localized to linear plasmids.
15 ns, including a 950-kb linear chromosome and linear plasmids.
16 mosome and a number of variable circular and linear plasmids.
17 and multiple antibiotics, and possess large linear plasmids.
18 ch regions can be efficiently manipulated in linear plasmids.
19 n of circular subgenomes with CMS-S-specific linear plasmids.
20 rgdorferi has over 20 different circular and linear plasmids.
21 linear plasmid (lp25), and either the 28-kb linear plasmid 1 or 4 (lp28-1 and lp28-4, respectively)
23 dification (R-M) systems, BBE02 contained on linear plasmid 25 (lp25) and BBQ67 contained on lp56, ha
26 rated a deletion mutant designated ES10 in a linear plasmid 25-negative isolate of B. burgdorferi str
27 nactivation and genetic complementation of a linear plasmid-25-encoded gene (bbe16) to assess its rol
28 B. burgdorferi spirochetes that lack the linear plasmid 28-1 (lp28-1) succumb to the host's immun
32 onger infectious and lacked genes encoded on linear plasmids 38 and 28-1, among other differences.
33 revealed significant upregulation of several linear plasmid 54 (lp54)-encoded open reading frames (OR
34 mid-encoded genes of B. burgdorferi, several linear plasmid 54 (lp54)-encoded open reading frames (OR
35 the core Borrelia genome (linear chromosome, linear plasmid 54 and circular plasmid 26) that encode f
36 ates numerous genes encoding lipoproteins on linear plasmid 54 in response to environmental cues.
38 a mutant of 297 (M297) that lacks the 49-kb linear plasmid and expression of outer surface proteins
39 evealed that the gene was located on a 53-kb linear plasmid and that there was only one locus for the
40 Bidirectional replication of Streptomyces linear plasmids and chromosomes from a central origin pr
42 By modification of palindrome-generating linear plasmids and development of a novel procedure tha
43 locations within telomeres of streptomycete linear plasmids and investigated mechanisms that enable
45 zed and contains a linear chromosome, twelve linear plasmids and nine circular extra-chromosomal elem
47 exchange of genetic information between the linear plasmids and the right end of the linear chromoso
52 a burgdorferi contains abundant circular and linear plasmids, but the mechanism of replication of the
54 able to repair transformed dephosphorylated linear plasmids by non-homologous end joining with consi
56 richia coli accumulate high-molecular-weight linear plasmid concatemers when transformed with plasmid
57 . rochei chromosome and to 100-kb and 206-kb linear plasmids contained in S. rochei, were isolated an
58 e recombinant loci generated by insertion of linear plasmids containing either base-pair substitution
60 e rlrA/rorA locus of pSLA2 were seen also on linear plasmids derived from the unrelated SLP2 replicon
61 r Genomic Research) maps to one of the 28-kb linear plasmids (designated lp28-4) that is not present
62 he maternal (stromal) parent possessed three linear plasmids, designated Callan-a (7.5 kb), Aubonne-a
64 in vitro patterns of KMnO(4) modification in linear plasmid differed from that in supercoiled plasmid
66 a, or ku80delta hdf1delta strains: repair of linear plasmid DNA and repair of an HO endonuclease-indu
68 tive within the procapsid and recircularizes linear plasmid DNA containing two terminal loxP recognit
69 The ability of each homologue to cross-link linear plasmid DNA has been determined, with a rank orde
70 products suggests that high-molecular-weight linear plasmid DNA is a substrate for RecBCD-mediated re
71 dimer forms stable complexes at both ends of linear plasmid DNA that protect the DSBs from digestion
72 clease-null AdnAB is a helicase that unwinds linear plasmid DNA without degrading the displaced singl
76 lution and the mobilities of circular versus linear plasmid DNAs were also affected by the chemical f
78 inding protein (SSB) in reactions containing linear plasmid dsDNA allowed us to study the AdnAB helic
80 s) of polintons, virophages, and cytoplasmic linear plasmids encompass an N-terminal domain homologou
81 ccomplish replication of telomere-containing linear plasmids, expression of rlrA, which encodes two L
82 frequent occurrence of ectopic integration, linear plasmid formation, and spontaneous resistance to
83 t least two successive rounds of addition of linear plasmid genetic material to the chromosomal right
85 e near the right telomere are often found on linear plasmids in B. burgdorferi (sensu stricto) isolat
86 and circular forms in B. turicatae but only linear plasmids in B. parkeri, which should be of intere
87 spirochetes and is carried on variably sized linear plasmids in both Borrelia parkeri and B. turicata
88 y presents evidence of a common ancestor for linear plasmids in Micrococcus and suggests that horizon
90 ently renamed mlp, was found on circular and linear plasmids in the genome sequence of B. burgdorferi
91 d-derived DNA probes used were also found on linear plasmids in the related Eurasian Lyme agents Borr
97 s that possess the gene carry it on a 200-kb linear plasmid (lp200), whereas isolates that lack the g
98 mosomal telomere with a large portion of the linear plasmid lp21, which is present in the strain B31
103 tal data suggest that two of these elements, linear plasmids lp25 and lp28-1, play essential roles fo
105 y the 9-kb circular plasmid (cp9), the 25-kb linear plasmid (lp25), and either the 28-kb linear plasm
108 -kb linear plasmid lp25 and one of the 28-kb linear plasmids (lp28-1) are required for experimental i
109 aracterize the role of one of the four 28-kb linear plasmids, lp28-3, we generated strains specifical
114 tion, but the genetic elements necessary for linear plasmid maintenance have not been experimentally
115 er chromosomes by transient integration, but linear plasmids may lead the donor chromosome end-first
116 Our observations suggest that Streptomyces linear plasmids may occupy an evolutionarily intermediat
117 d encodes, in its chromosome and each of the linear plasmids, members of the lambda exonuclease famil
118 These vectors identify internal regions of linear plasmids necessary for autonomous replication in
121 y, we demonstrate that a factor encoded on a linear plasmid of B. burgdorferi, lp17, can negatively r
122 lp6.6 gene, which was localized to the 49-kb linear plasmid of B. burgdorferi, subsequently was clone
125 ied protein attached to the end of the pSLA2 linear plasmid of Streptomyces rochei, determined the N-
126 covalently bound to protein, pSLA2, a 17 kb linear plasmid of Streptomyces rochei, initiates replica
128 and little characterized to date, are large linear plasmids of approximately 160 kb, or approximatel
131 ethods, we determined the sequences of large linear plasmids of two New World species: Borrelia herms
132 sequence of the 51,601-bp Klebsiella oxytoca linear plasmid pKO2, and we demonstrate experimentally t
133 Additionally, the successful transfer of the linear plasmid pLMA1 by a DNase-insensitive, conjugation
135 lasmids with sequence similarities to the 12 linear plasmids present in the B. burgdorferi type strai
139 only phages N15 and PY54 are known to have a linear plasmid prophage with closed hairpin telomeres.
142 all B. burgdorferi clinical isolates contain linear plasmids related to each other, but the structure
143 n analyzed biochemically, and their roles in linear plasmid repair in vivo have been verified genetic
145 alyses provide insight into the mechanism of linear plasmid replication and the mechanisms by which p
147 gene cluster, which is located on the 356-kb linear plasmid SCP1 of Streptomyces coelicolor A3(2).
150 ion of infectivity with strains possessing a linear plasmid (size range, 24 to 36 kb) that hybridized
151 ded Orfs encoded by several ORFs of the lp36 linear plasmid, such as BBK07 and BBK19, and proteins of
153 a suggest that Polintons have evolved from a linear plasmid that acquired a retroviral integrase at l
154 Here we identify 11 genes localizing to linear plasmids that are up-regulated at pH 7.0 relative
156 ing; and (iii) formation of long palindromic linear plasmids that duplicate the intact telomere by a
157 relia carry a linear chromosome and numerous linear plasmids that have covalently closed hairpin telo
158 vspA and vspB were each located on different linear plasmids that were the same in both serotypes.
161 A 3.0-kb HindIII fragment of the 24.7-kb linear plasmid was used as a probe to determine the pres
162 The central approximately 25 kb of all 4 linear plasmids was syntenic for orthologous genes for p
166 dorferi (sensu stricto), for the presence of linear plasmids with sequence similarities to the 12 lin
167 p subfamily of alleles, which are carried on linear plasmids within each cell and maintained in sever