ライフサイエンスコーパス: lining

1 liver parenchyma, and lipase in the stomach lining.

2 f cases (22/30) showed discontinuous mucosal lining.

3 ield and the need to reconstruct the mucosal lining.

4 in 87.5% of cases with discontinuous mucosal lining.

5 phage-like component of the liver sinusoidal lining.

6 s depends on toxin-induced damage to the gut lining.

7 eases are located outside of the endothelial lining.

8 es in lipid membranes with the polyol region lining a channel interior that funnels to its narrowest

9 In contrast, additional residues lining a contiguous adjacent surface on the C-terminal d

10 hereby promoting growth of a new endothelial lining across the aneurysm opening.

11 tivity is provided by highly conserved, pore-lining amino acids.

12 nodules, continuous or discontinuous mucosal lining and cholelithiasis may indicate XGC rather than g

13 e CHT niche, and mature into reticular cells lining and interconnecting sinusoids.

14 was evident with loss of luminal epithelial lining and mural stroma necrosis.

15 ternal immunological barrier at the synovial lining and physically seclude the joint.

16 Two dorsal skin flaps represented nasal lining and skin envelope.

17 issue composed mainly of fibroblasts, with a lining and sublining that surround the joints.

18 ular cartilage, inflammation of the synovial lining, and changes to the subchondral bone.

19 e and skin to restore bone defects, internal lining, and external coverage.

20 ctor fibroblasts located in the synovial sub-lining, and FAPalpha(+)THY1(-) destructive fibroblasts r

21 n pore size/geometry, the nature of the pore lining, and rates of water transport.

22 age-like component of the liver blood vessel lining, are traversed by sporozoites to initiate liver i

23 ction scale based on graft skin and urethral lining as the main targets of rejection.

24 Endoscopy demonstrated a complete mucosal lining at 15 months, despite retention of a stent.

25 ared with the measured cellularity of the CC lining at P15.

26 oliferation, the total cellularity of the CC lining at the L4 spinal segment significantly descended

27 Human cholangiocytes, epithelial cells lining bile ducts, were cultured as polarized epithelia

28 ammogram, uterine ultrasound, or endometrial lining biopsy.

29 emerging contractile nature; similarly, ECM lining blood vessels is highly elastic in order to susta

30 ion is bacterial interaction with endothelia lining blood vessels, which is physically challenging be

31 ging pathogen that targets endothelial cells lining blood vessels; the high mortality rate (up to 70%

32 staining revealed intact colonic epithelial lining, but extensive damage in jejunal villus tips afte

33 Pore-lining carbonyl groups are well situated to stabilize hy

34 ng transcriptomic profiling of isolated bone lining cell subtypes from a murine myeloma model, we fin

35 profiling in bone cells, we identified bone lining cells as important gatekeepers of estrogen-contro

36 nction, we examined the mitochondria of cyst-lining cells in ADPKD model mice (Ksp-Cre PKD1 (flox/flo

37 merism, as shown by the presence of vascular lining cells of recipient origin.

38 These findings provide insight into how cyst-lining cells respond to 4E-BP1.

39 cumulation of phosphorylated SMAD2/3 in cyst-lining cells suggests the involvement of TGF-beta signal

40 AC), and synovial hyperplasia with increased lining cells was found.

41 s of mice with ADPKD, JAK2 is higher in cyst-lining cells when compared to normal tubules and critica

42 ing osteoblast apoptosis and activating bone-lining cells.

43 ated suppression of RANKL expression in bone lining cells.

44 tor (pIgR) is highly expressed by renal cyst-lining cells.

45 d that secreted ST6Gal1 is produced by cells lining central veins in the liver and that IgG sialylati

46 ier (BBB) is formed by the endothelial cells lining cerebral microvessels, but how blood-borne signal

47 cing speckles are observed nearby within the lining channel system.

48 fied the small heat shock-like SIEVE ELEMENT-LINING CHAPERONE1 (SLI1).

49 four-fold enhanced retention in the gastric lining compared to monocompartment motors, while showing

50 d the lamina propria and an inner epithelial lining composed of layers of basal, intermediate, and su

51 ted residues, interaction of a proposed pore-lining cysteine at position 37 with the positively charg

52 mucosal regeneration, and improve urothelial lining defects in KIC.

53 tiation, which might attribute to urothelial lining defects.

54 orts of the mitotic activity observed in the lining during postnatal development have often been cont

55 The inner uterine lining (endometrium) is a unique tissue going through re

56 unidentified role for microvessels and their lining endothelial cells in engulfing myelin debris in s

57 Consistent with these results, cyst-lining epithelial cells from human ADPKD kidneys had a t

58 MIF was upregulated in cyst-lining epithelial cells in polycystin-1-deficient murine

59 emerging evidence indicates that changes in lining epithelial cells may also contribute to increased

60 strong dot-like perinuclear staining in the lining epithelial cells, suggesting that RD3 may play an

61 AP transcriptional activity in the bile duct-lining epithelial cells.

62 Wider nanopores with hydrophobic linings favor water flow whereas narrower hydrophobic po

63 Endothelial cells lining fetal and newborn arteries have an unusual phenot

64 , changes in the cross-sectional area of the lining flap were measured when negative pressure was app

65 halation overpower the strength of the nasal lining flap.

66 We have shown that human alveolar lining fluid (ALF) contains homeostatic hydrolases capab

67 that age-associated changes in the alveolar lining fluid (ALF) may increase susceptibility by alteri

68 alveoli and comes into contact with alveolar lining fluid (ALF), which contains homeostatic and antim

69 ctive oxygen species (ROS) in the epithelial lining fluid (ELF) of the human respiratory tract.

70 The lung lining fluid (LLF), which contains phospholipids and sur

71 achieved higher concentrations in epithelial lining fluid and alveolar cells than plasma.

72 f ROS in different regions of the epithelial lining fluid by considering particle-size-dependent resp

73 lung recruitment correlate with altered lung lining fluid composition independent of age or genotype.

74 n the basis of a synthetic respiratory tract lining fluid containing the antioxidants glutathione and

75 ad to the formation of ROS in the epithelial lining fluid due to redox reactions of PM components wit

76 diator levels in samples of nasal epithelial lining fluid during episodes with asthma-like symptoms a

77 ch are similar to levels found in epithelial lining fluid from healthy adults, did not induce IL-1bet

78 temic exposure of omadacycline in epithelial lining fluid is greater than/equal to plasma concentrati

79 lung diffusing capacity, abnormal epithelial lining fluid metabolome profile, increased proportions o

80 as biological parameters of lung epithelial lining fluid metabolome, small airway epithelial (SAE) c

81 and 49.8-fold (95% CI: 34.2-65.3) higher in lining fluid than plasma respectively.

82 n blood, whole lungs, or alveolar epithelial lining fluid to include measurements in specific types o

83 SOCS secretion into lung lining fluid was diminished by cigarette smoking in huma

84 Simultaneously, unstimulated airway mucosal lining fluid was obtained and quantified for levels of 2

85 Soluble mediators in the nasal lining fluid were measured using nasosorption.

86 s measured in plasma, lung/airway epithelial lining fluid, and alveolar cells.

87 were increased in macrophages, sputum, nasal lining fluid, and plasma of patients with N-ERD.

88 airway epithelial cell membranes or the lung-lining fluid, generating chemically reactive oxysterols.

89 ight junctions secrete mucus, airway surface lining fluid, host defense peptides, and antioxidants an

90 only used to collect upper airway epithelial lining fluid, nasal washes are poorly reproducible, not

91 Metabolites in nasal lining fluid, sputum, and plasma from patients with N-ER

92 drugs was performed in plasma and epithelial lining fluid, using a population model.

93 d a concentration of 32 nmol/L in epithelial lining fluid, with associated increases in BALF IL-1beta

94 LAmB localizes in lung epithelial lining fluid, within liver and splenic macrophages and i

95 chemokines were quantified in airway mucosal lining fluid.

96 f surfactant lipids and proteins in the lung lining fluid.

97 L-1beta, IFN-beta, and MIF in their alveolar lining fluid.

98 In nasal lining fluids of allergic patients challenged with aller

99 ic side, lipids penetrate as far as the pore-lining helices and lipid molecules can align along TM3b

100 e highly conserved Y2807 of the CTD and pore-lining helices are required to ensure normal mechanosens

101 at the inner and outer ends of adjacent pore-lining helices come closer during opening, likely throug

102 ndle crossing and the splaying apart of pore-lining helices commanding ion passage.

103 is due to the repositioning of tethered pore-lining helices within a surrounding protein shell that d

104 SET to substituted cysteines in all the pore-lining helices, we show that the state-dependent accessi

105 on pore lined by the side chains of the pore-lining helices.

106 en these states through movement of the pore-lining helices.

107 tions of the gating ring and bending of pore-lining helices.

108 The RyR1 S6 pore-lining helix has two conserved glycines, Gly-4934 and Gl

109 he role of RyR1-G4934 and -G4941 in the pore-lining helix in channel gating and ion permeation was pr

110 h notable conformational changes of the pore-lining helix S1, which swings nearly 60 degrees towards

111 events desensitization by anchoring the pore-lining helix to the membrane with palmitoyl groups.

112 ves a secondary structure change of the pore-lining helix, which contains a pai-helical segment in th

113 ted by palmitoylated cysteines near the pore-lining helix.

114 Activation of human ECs lining human coronary artery grafts in immunodeficient m

115 tion in Gdf5-lineage cells prevents synovial lining hyperplasia and decreases contribution of Gdf5-li

116 P8 and only 0.6% +/- 0.2% of cells in the CC lining in adulthood are proliferating.

117 ion and determines the cellularity of the CC lining in reference to lumbar spinal segment L4 during t

118 , the transformation of the gastrointestinal lining, increases in postprandial gut hormone secretions

119 does not require debriding of the urothelial lining, injection into the bladder wall, specialized ima

120 mational changes coupled to the pair of pore-lining inner helices from the first 6-TM domains, wherea

121 ally conserved inactivation gate in the pore-lining inner helix of mouse Piezo1 and Piezo2 that is di

122 highly conserved TM1 helix acts as the pore-lining inner helix, creating an hourglass-shaped ion per

123 Discontinuous mucosal lining is evident in xanthogranulomatous cholecystitis.

124 ings, we conclude that discontinuous mucosal lining is not an unusual finding in cases of XGC.

125 The upper aerodigestive tract mucosal lining is often disrupted during surgery, which requires

126 ered polypeptides, known as FG nucleoporins, lining its passageway.

127 exRNA was detectable only in the RA synovial lining layer, whereas extracellular DNA was detectable i

128 ctive fibroblasts restricted to the synovial lining layer.

129 brane proteins located within the intestinal lining, leading to growth inhibition and mortality.

130 anize three-dimensionally to form a synovial lining-like layer.

131 osine monophosphate (cAMP) in cholangiocytes lining liver cysts.

132 flexibility of specific and relevant surface lining loops, which previously was not detected by X-ray

133 nduce changes that lead to asynchronous pore-lining M2 helix movements.

134 ormation, the extracellular-half of the pore-lining M2 is splayed open, reminiscent of the open confo

135 ent to systematically probe the role of pore-lining M2 residues in GluN1 and GluN2A in the channel bl

136 located at the extracellular end of the pore lining M2 transmembrane segment (18').

137 we identify a subset of lymphoid organ sinus lining macrophage (SMs) that provide a cell-cell contact

138 lammation, these epithelial-like CX(3)CR1(+) lining macrophages restrict the inflammatory reaction by

139 nfection of the choroid plexus and ependymal lining, marked meningitis, and 100% mortality within 2 w

140 Mucosal lining may be continuous or discontinuous in XGC.

141 ensor uniquely expressed in epithelial cells lining mucosal surfaces.

142 immune response of barrier epithelial cells lining mucosal surfaces.

143 nt study demonstrates that endothelial cells lining newborn central arteries express high levels of E

144 CD133(+) ependymal neural stem cells (NSCs), lining not only the lateral but also the fourth ventricl

145 The vascular endothelium forms the inner lining of blood vessels and actively regulates vascular

146 binding of infected cells to the endothelial lining of blood vessels as a strategy to avoid clearance

147 M scaffold and spontaneously repopulated the lining of decellularized vessels.

148 Dysfunction of the endothelial lining of lesion-prone areas of the arterial vasculature

149 alpha immunoreactivity along the endothelial lining of lesions from transgenic animals compared with

150 rolled ependymal cells along the ventricular lining of the aqueduct.

151 uently progressively colonize the epithelial lining of the endometrium.

152 tion in which the normal squamous epithelium lining of the esophagus is replaced by goblet cells.

153 The intestinal mucosa comprises the inner lining of the intestinal tract and maintains close proxi

154 last-like synoviocytes (FLS), which form the lining of the joint, are epigenetically imprinted with a

155 uch as host cell adhesion to the endothelial lining of the microvasculature.

156 The outer lining of the ovary (cortex) has a key role in defining

157 The motions of the lining of the peptide tunnel appear to assist in the exp

158 does not change topology to accommodate the lining of the pore lumen by BGH.

159 neurons and glia from the central canal (CC) lining of the spinal cord in rodents should occur in the

160 ivation of all three loci in the mesothelial lining of the thoracic cavity leads to a highly aggressi

161 erapy-resistant cancer affecting the serosal lining of the thoracic cavity.

162 The mucosal lining of the upper airways represents the outer surface

163 Urothelium is the protective lining of the urinary tract.

164 The endometrial lining of the uterine cavity is a highly dynamic tissue

165 tyrosine kinase expressed in the epithelial linings of the gastrointestinal tract and the skin, wher

166 e presence of dividing cells peaks in the CC lining on postnatal day 8 (P8), with division occurring

167 ve stomach acid and decomposed in intestinal linings or after absorption to simultaneously release AS

168 n array of specialized epithelial cell types lining organs, including the thyroid, thymus, lungs, liv

169 ompanied by the suppression of the endosteum-lining osteoblast population.

170 Bzb treatment accelerated DNA repair in bone-lining osteoblasts and thus promoted their survival.

171 The intestinal epithelial cell lining provides the first line of defense, yet foodborne

172 n, pore dilatation by a mutation in the pore-lining region alters the anion selectivity of GlyR.

173 that asparagine 171 (N171) is the only pore-lining residue required for high-affinity block, and tha

174 16A structure and identification of its pore-lining residues are essential.

175 CAM), we evaluated the role of possible pore-lining residues in the permeation of ions and ethidium t

176 within transport-domain TMs, identified pore-lining residues of functional importance, and provided e

177 d correlated variation between the S3-pocket-lining residues of uPA and the P3 residue of both PAI-1

178 lights four previously underappreciated pore-lining residues specifically conserved in Best2 but not

179 ect anion selectivity, as well as seven pore-lining residues that cluster near pore constrictions and

180 cation of zinc and water suggested that pore-lining residues undergo a mode switch between zinc coord

181 We find that two rings of pore-lining residues, V102 and F99, work together to form a h

182 rganoids integrate into the endothelial cell lining, resulting in mosaic vessels with gaps in the bas

183 ar rotation of the upper portion of the pore-lining S6 helix away from the 4-fold channel axis and tw

184 Endothelial cells lining SC elaborate tight junctions (TJs), down-regulati

185 closest to the APOL1 C terminus as the pore-lining segment of this novel channel-forming protein.

186 Our results indicate that CC lining serves as a source of cells beyond ependymal cell

187 pathogen barrier, regions lacking cuticular lining, such as the shrimp's excretory organ, "the anten

188 ough immunohistochemistry, we found that the lining synovial intima of the stifle (knee) is a target

189 center, and movements of the peptide tunnel lining that assist in the expulsion of the synthesized p

190 ntamers containing substitutions to residues lining the 5-fold pore did not affect pentamer assembly

191 is dispensable for DNA binding but residues lining the active site guide DNA for cleavage.

192 in the superficial layer of epithelial cells lining the airways.

193 ducting airways and type II and type I cells lining the alveoli.

194 METHODS AND LD were present in EC lining the aorta after the peak in plasma triglycerides

195 Cholangiocytes, the epithelial cells lining the biliary tree in the liver, express primary ci

196 shots reveal that the amino acid side chains lining the binding pockets switch in a coordinated fashi

197 Residues lining the binding site are highly conserved among filov

198 The urothelium is an epithelial barrier lining the bladder that protects against infection, flui

199 yield tumors in the transitional epithelium lining the bladder, kidneys and ureters.

200 nctional) endothelial cells (ECs), the cells lining the blood vessel lumen.

201 hysical integrity of endothelial cells (ECs) lining the blood vessels regulates the inflammatory resp

202 ibuted to mechanisms restricted to the cells lining the boundary.

203 nds on cilia motility of the ependymal cells lining the brain ventricles, which play a crucial role t

204 ach other by completing the hydrophobic core lining the central part of HP35.

205 andidate for inserting into the membrane and lining the channel.

206 opropane (dmpn) appended to the Mg(2+) sites lining the channels of Mg2(dobpdc) (dobpdc(4-) = 4,4'-di

207 branched dilated microvessels in the tissues lining the clinically healthy GC.

208 A single layer of polarized epithelial cells lining the colonic mucosa create a semipermeable barrier

209 tructural cells (especially epithelial cells lining the conducting airways) are pivotal for the effic

210 ing the transport core and TM11-TM12 helices lining the dimer interface.

211 of the molecular properties of the residues lining the egress path suggest that protein surface elec

212 We found that the columnar epithelial cells lining the endocervix, the lower part of the uterus, are

213 glycocalyx (GCX), a carbohydrate-rich layer lining the endothelium, is crucial in vascular homeostas

214 oteasome subunits/targets and lipidated ATG8 lining the enveloping autophagic membranes.

215 he large intestine, with its array of crypts lining the epithelium and diverse luminal contents, regu

216 In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the

217 ain and the negatively charged ribosomal-RNA lining the exit tunnel, and for quickly ejecting protein

218 e-1 (GLP-1), an incretin secreted by L-cells lining the gastrointestinal epithelium, has important fu

219 the branched dilated microvessels in tissues lining the GC.

220 lamydia trachomatis targets epithelial cells lining the genital mucosa.

221 invading microbes interact with host mucins lining the glandular epithelial cells and trigger inflam

222 Videomicroscopic images from tissues lining the healthy GC in 20 healthy volunteers were anal

223 ity, binding exclusively to glycans on cells lining the human airway where terminal sialic acids are

224 confirmed by immunohistochemistry in the EC lining the human coronary vessel.

225 Mutagenesis of residues lining the identified interaction site on Bcl-B negated

226 ical signals by endothelial cells, the cells lining the interior of blood vessels.

227 ssembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the h

228 accharides comprising part of the host diet, lining the intestinal mucosal layer, and decorating the

229 terminants attributable to distinct residues lining the intramembranous pocket in the two receptor su

230 residues (known as the phenylalanine clamp) lining the junction between the cap and the stem.

231 by a double spiral of electropositive loops lining the katanin central pore.

232 mal pathway causing dysfunction of the cells lining the kidney proximal tubule (PT).

233 G could be imaged in the superficial tissues lining the labial sulcus.

234 eous with a mitotically active subpopulation lining the lateral domains of the central canal (CC) tha

235 D318, and L320 in the lower body beta-sheets lining the lateral portals.

236 The ECG is a surface layer lining the luminal walls of blood vessels composed of pr

237 In vitro, the hESC-ECs lining the luminal walls readily sprout and anastomose w

238 ZM) are strategically located in the spleen, lining the marginal sinus where they sense inflammation

239 ed neutrophil chemoattractants, whereas LECs lining the medullary sinus (MS) expressed a C-type lecti

240 In contrast, any replacement of His(237), lining the metal exit route, locked the transporter in a

241 ne vesicles shed into the urine by the cells lining the nephron.

242 a characteristic hyperpolarization of cells lining the neural tube; disruption of this spatial gradi

243 f the nuclear lamina, a filamentous meshwork lining the nucleoplasmic side of the inner nuclear membr

244 Cells lining the OF margin can maintain RPE fate ectopically a

245 ls and alcohols oriented in the side pockets lining the one-dimensional pores.

246 known as the embryonic node and crown cells lining the outer periphery of the node.

247 any microbial pathogens and affect the cells lining the peritoneal cavity by triggering local inflamm

248 ablishing hydrophobic contacts with residues lining the pore.

249 Furthermore, several residues lining the presumptive binding pocket for noxious GAs ar

250 Cells lining the proximal tubule (PT) have unique membrane spe

251 Cells lining the proximal tubule (PT) of the kidney are highly

252 by mutation of individual conserved residues lining the putative ligand-binding surface of the C-term

253 athione) from a synthetic model of the fluid lining the respiratory tract.

254 80-E216 enzymatic tetrad as well as residues lining the RNA binding groove, and offers previously uni

255 target DNA access to key catalytic residues lining the RuvC pocket.

256 Cationic Arg or Lys side chains lining the S4 helix move through this "gating pore" when

257 Among the residues lining the SBS-A1 site, two (Gln(700) and Tyr(717)) prom

258 non-uniform, with greatest density in cells lining the scala tympani and lower density in neural tar

259 l three species, including endothelial cells lining the Schlemm's canal.

260 also localized NC inside wild-type cores and lining the spherical Gag shell in immature virions.

261 LECs lining the subcapsular sinus (SCS) of LNs abundantly exp

262 21 scavenging by lymphatic endothelial cells lining the subcapsular sinus ceiling stabilizes interfol

263 The sequences of Thal and RebH lining the substrate binding site differ in only few res

264 of vSGLT, we identified and mutated residues lining the sugar transport pathway to cysteine.

265 lex hair-like organelles of epithelial cells lining the surface of various organ systems.

266 g the tightly packed core and polar residues lining the surface.

267 yndrome caused by invasion of the epithelium lining the terminal ileum, colon, and rectum by Shigella

268 elial-to-mesenchymal transition (EMT), cells lining the tissue periphery break up their cohesion to m

269 ediated by the movement of the flexible wall lining the two regions.

270 ocalyx, a glycosaminoglycan (GAG)-rich layer lining the vascular lumen, is associated with the onset

271 Endothelial cells (ECs) lining the vasculature of vertebrates respond to low oxy

272 By lining the vasculature, they provide a barrier to tissue

273 nt activation of the endothelial cells (ECs) lining the vein, in the absence of overt mechanical disr

274 ed within microglia, and the ependymal cells lining the ventricles of the brain expressed all three p

275 grey-white matter junctions, and structures lining the ventricles; all cases of acute blast exposure

276 ration of ciliary beating on ependymal cells lining the ventricular walls.

277 Endothelial cells lining the vessel wall control important aspects of vasc

278 The monolayer of endothelial cells lining the vessel wall forms a semipermeable barrier (in

279 biological effects on the endothelial cells lining the vessel wall.

280 ns and a decrease in hydrophobic side chains lining the vestibule, and this was reflected in solvatio

281 ~340 degrees C, serpentinization of olivine lining the walls of the fluid inclusions leads to a near

282 served hydrophilic residues in DraNramp, one lining the wide intracellular vestibule for metal releas

283 illing in apparent gaps in the non-beta-cell lining, the mind interprets it as a "whole" mantle, whic

284 cificity is conferred by amino acid residues lining their substrate pocket that distinguish them from

285 oots were found only in the epithelial cells lining these secretory ducts.

286 ic disease, uterine fibroids, or endometrial lining thickness as assessed by clinical examination, ma

287 onformational flexibility of the Cys364-loop lining this channel.

288 hydrophobic interactions with all five pore-lining threonine residues of the pentameric receptor.

289 Graft skin and urethral lining tissue are first rejection targets followed by tu

290 ansmembrane domains, and further to the pore-lining TM2 through two pathways: pre-TM1 and the beta1-b

291 n alpha-to-pi-helical transition in the pore-lining transmembrane helix S6 at an alanine hinge just b

292 alpha-to-pai helical transition in the pore-lining transmembrane helix S6.

293 measurements show that mutation of two pore-lining tyrosine residues, Tyr-23 and Tyr-149 in sheep AQ

294 es from the structure-activity relationships lining up the antitubercular activity were exploited for

295 ons at its most apical side, the ventricular lining (VL).

296 le actin expression, whereas the endothelial lining was mostly intact.

297 After reperfusion, the colonic epithelial lining was not affected, whereas the jejunal epithelium

298 Discontinuous mucosal lining was seen in all cases with wall thickness >10 mm,

299 live bacteria mimicking the infected stomach lining, we found that H. pylori infection is associated

300 en and closed states reveal a dynamic tunnel lining, with implications for gating or substrate transl