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1 all four consensus functional domains to be linked.
2 demonstrate the first synthesis of vinylene-linked 2D CPs, namely, 2D poly(phenylenequinoxalinevinyl
4 Drug PK assays for next-generation disulfide-linked ADCs involving immunoaffinity capture, chemical c
5 bon electrode (SPCE) using chitosan as cross-linked agent for 5-HT sensing studies; conducted through
7 en in a Caenorhabditis elegans model of SOD1-linked ALS identified the USP7 ortholog as a suppressor
8 ments were realized upon replacing the ether-linked amines with carbon-linked morpholines, a modifica
9 ed that, compared with the NiPc-based and NH-linked analogs, CoPc-based and O-linked MOFs have lower
11 channels and demonstrates that large disease-linked and experimentally generated C-terminal truncated
12 in responses to drug and nondrug reward are linked and together form a risk profile for drug use or
13 uripotency progression and morphogenesis are linked and whether intermediate pluripotent states exist
14 ted by the selective cleavage of a tetrazine-linked antibody-drug conjugate by trans-cyclooctenes, af
15 n be complemented by genomic information and linked back to extant communities via network structure,
16 ort an unexpected role of nutrient-sensing O-linked beta-N-acetylglucosamine (O-GlcNAc) signaling in
17 by pentaglycine cross-bridges that are cross-linked between adjacent wall peptides by penicillin-bind
18 atic hydrocarbon (PAH) chromophores that are linked between two five-membered rings can access planar
19 ry 1, 1996 to December 31, 2015 using record-linked birth and hospitalisation data from Denmark, Scot
23 pectra of a two-fold interpenetrated Hf MOF, linked by 1,4-phenylene-bis(4-ethynylbenzoate) ligands (
25 es related to eruptions at arc volcanoes are linked by structures that transect the entire crust.
27 Biophysical studies on single cells have linked cell mechanics to physiology, functionality and d
28 erein, we report the synthesis of a vinylene-linked (-CH=CH-) covalent organic framework, COF-701, di
29 in global mean surface temperature, which is linked closely with the water-holding capacity of the at
33 s nationwide register-based cohort study, we linked data from the Swedish MS register to the Swedish
37 yielding a nonhydrolyzable phosphonothiolate-linked diubiquitin and an ubiquitin-alpha-synuclein conj
39 ber 2016; total person-years 6,498,607) with linked FHS utilization and mortality records was analyze
40 frameworks and cannot be accessible by imine-linked frameworks, amorphous analogues, and 1D conjugate
42 ltered self" on target cells, via a membrane-linked gammadelta TCR recognizing intact non-MHC protein
43 ssed with mice of both sexes, expressing ALS-linked gene mutants for TAR DNA-binding protein (TDP-43)
45 suggested that the two acuities are strongly linked given that they both depend strongly on retinal e
46 ression of both tumor-associated truncated O-linked glycans and their receptor, macrophage galactose-
50 in the NA head domain of H1N1 IAVs, three N-linked glycosylation sites are conserved and that a four
51 at in addition to antigenicity, changes in N-linked glycosylation sites can alter other properties of
56 eurofilament light chain (NfL), using enzyme-linked immunosorbent assay and electrochemiluminescence.
57 n peri-implant crevicular fluid using enzyme-linked immunosorbent assay method and assessed with clin
60 ntibody titer (measured by inhibition enzyme-linked immunosorbent assay) and dengue severity, categor
63 ies to a panel of class 5 adhesins in enzyme-linked immunosorbent assays (ELISAs) revealed several re
64 pared to three commercially available enzyme-linked immunosorbent assays (ELISAs) targeting the nucle
65 ters, cell-mediated immunogenicity by enzyme-linked immunospot, functional neutralizing antibodies, a
66 Glucagon and its partner insulin are dually linked in both their secretion from islet cells and thei
68 de age and tumor histology classified by age-linked International Neuroblastoma Pathology Classificat
69 gulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a lethal disease caused by mut
72 Analysis of clinical transplantation data linked low circulating levels of GDF15 to an increased i
75 ased and NH-linked analogs, CoPc-based and O-linked MOFs have lower activation energies in the format
77 inked to the reduction in molecular vinculin-linked molecular force as well as the downregulation of
78 eplacing the ether-linked amines with carbon-linked morpholines, a modification motivated by free ene
83 te the detection and identification of cross-linked peptides using multistage mass spectrometry (MS(n
90 elop in Wiskott-Aldrich syndrome (WAS), an X-linked primary immunodeficiency disorder (PID) resulting
91 ) is a complex and dynamic meshwork of cross-linked proteins that supports cell polarization and func
94 However, decisions are not guided by choice-linked reward associations alone; macaques also maintain
95 sialic acid binding is specific for alpha2-3-linked sialic acid and mediated by the exposed apical lo
97 block homeostatic apoptosis through alpha2,6-linked sialylation of the death receptor TNFR1 in many c
103 e remainder of the cardiovascular system and linked them to anti- and pro-thrombotic effects of aspir
108 s where organic functionalities are directly linked through the Si-C bond, unlike the industry's trad
109 -modification (R-M) system (SpnIII) has been linked to a change in capsule expression and to the abil
110 rophils into alveolar spaces, which might be linked to a decrease in the production of pro-inflammato
112 at rivaroxaban's antithrombotic potential is linked to a hitherto unknown rivaroxaban effect that imp
113 te that collagen secretion may be intimately linked to a hypoxic microenvironment within keloid tumor
116 tration of HSPCs in bone marrow after SCI is linked to aberrant chemotactic signaling that can be rev
117 interphase leads to cell cycle defects often linked to aberrant chromosomal condensation and segregat
119 d differences in the physiological processes linked to AFC in different EC levels and metabolic proce
124 ows high metabolic stability in all species, linked to an adequate pharmacokinetic profile in rodents
125 activation of NFkappaB signalling, which is linked to an increase in intracellular calcium oscillati
126 s in the homolog of the human CYFIP1, a gene linked to autism and schizophrenia, exhibit mitochondria
127 ion of the two most relevant genetic markers linked to azole resistance, the mutations TR34 and TR46,
128 iratory syndrome corona virus 2 pneumonia is linked to both acute respiratory distress syndrome and s
130 assimilation by plants may be symmetrically linked to carbon (C) transfer from plant to fungus or go
133 egulation of mitochondrial dynamics has been linked to cellular senescence, which contributes to adva
134 critical cellular "second messenger," may be linked to changes in cellular architecture that favor pa
135 through redox buffering circuits is directly linked to changes in oxygen consumption mediated by NNT.
136 e during embryonic development and have been linked to childhood epilepsy before, but the underlying
137 use frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) and can contribute to
139 of sleep neurophysiology were most strongly linked to cognitive performance in 3,819 older adults fr
140 Zika virus (ZIKV) infection is now firmly linked to congenital Zika syndrome (CZS), including feta
142 E point mutations in the C terminus that are linked to deafness disrupt phospholipid binding, sensiti
147 iad of cellular processes in plants that are linked to development, environmental responses and immun
148 ntext of time scales of the stress reaction, linked to different neural and functional consequences.
149 ncluding mutations in ZDHHC genes, have been linked to different neurological pathologies and cancers
150 ing in the single T. cruzi mitochondrion are linked to differentiation by a yet-unknown signaling mec
153 around specialist hospital centres that are linked to district general hospitals by operational deli
154 behavioral flexibility observed in disorders linked to dopamine perturbations may be attributable to
158 ts of Poland; maternally the individuals are linked to earlier Neolithic lineages, whereas on the pat
159 s exhibit enhanced activation of brain areas linked to emotional processing during the trust game.
162 idual differences in dogmatism, a phenomenon linked to entrenched beliefs in political, scientific, a
163 ackground warmth of the early Eocene, likely linked to eruptive phases of the North Atlantic Igneous
164 amily of proteins which have been previously linked to fasting glycaemic traits and insulin resistanc
170 -ribosylation of histones by PARP-1 has been linked to genotoxic stress responses, its role in physio
175 n infectious diseases pathogen resistance is linked to human leukocyte antigen (HLA) class I/II varia
177 l basal ganglia tissue iron levels have been linked to impaired cognition in iron deficient children
178 gs across anxiety and depression items, were linked to impoverished adjustment of learning to volatil
179 ure to exertional heat stroke (EHS) has been linked to increased long-term decrements of health.
181 ure to exertional heat stroke (EHS) has been linked to increased susceptibility to a second heat stro
182 e of intracellular aggregates, which was not linked to increased translation of IgG mRNA, but rather
183 d by cytochrome P450 (CYP) enzymes have been linked to increased tumor growth and metastasis, largely
184 8G single nucleotide polymorphism, have been linked to individual differences in pain sensitivity, de
185 scribe a specific example of a gAP in humans linked to individual differences in the response to stre
187 we have established the eicosanoid profiles linked to inhibition of COX-1 in platelets and in the re
189 9, hypergeometric test) enriched in pathways linked to insulin secretion and extracellular matrix-rec
190 This review describes the cellular pathways linked to IRF3 activation and where those pathways are t
191 arch advances demonstrate that FGF23 is also linked to iron economy, inflammation and erythropoiesis.
194 ma-associated herpesvirus (KSHV) is causally linked to Kaposi's sarcoma and several lymphoproliferati
195 known to affect mechanical gating and may be linked to large variability in tension sensitivity among
196 ing of the mechanisms of virus-mediated pain linked to latency and reactivation.IMPORTANCE The reacti
197 irst-cycle capacity loss is a kinetic effect linked to limited Li mobility at x > 0.88, with near ful
198 ury-induced neointimal hyperplasia, diseases linked to loss of vascular smooth muscle differentiation
199 t not of IgG or IgA against FceRIalpha, were linked to low blood basophil (r = .414, P = .021) and eo
202 ated fatty acids (LC omega-3 PUFA) have been linked to major depressive disorder (MDD) and preterm bi
203 s which have become public health priorities linked to major hospital outbreaks and the recent emerge
204 ities, or number sense, has been recurrently linked to mathematical skills, although the nature of th
206 DNA binding capabilities are mechanistically linked to methylation variability in mammals, with impli
208 signals in red nucleus (RN), a brain region linked to motor control, as male and female rats perform
209 apping to identify modulators of HSC biology linked to MPN risk, and show through targeted variant-to
211 , 0.59; 95% CI, 0.37-0.93) were particularly linked to myocardial infarction, whereas high HDL oxidat
212 these asymmetric domain arrangements are not linked to negative cooperativity and hemiphosphorylation
215 e pre-mRNA that is alternatively spliced and linked to neurodegenerative diseases is tau (microtubule
216 eural circuitry, and its disruption has been linked to neurodevelopmental disorders such as autism an
217 els and interleukin-6 levels (which has been linked to nonosmotic release of vasopressin) was assesse
219 nistrative databases in Ontario, Canada were linked to obtain records of all patients with diabetes w
221 dentified a subset of phenotypes that can be linked to p120-catenin in epithelial integrity and turno
223 were strongly correlated with habitat shifts linked to particular soil conditions; 81.7% of edaphic v
227 ocus group discussions that are most closely linked to policy changes and descriptive analyses of the
228 umor and its tumor microenvironment (TME) is linked to poor clinical outcomes in treatment of resista
230 imordial dwarfism in domesticated animals is linked to positive selection in minor spliceosome compon
232 genes in nuclear space has been extensively linked to regulation of gene expression, but the mechani
233 t is unclear how such biological changes are linked to relevant, pathological neurochemistry, and bra
234 and lysine-27 tri-methylation (H3K27me3) are linked to repression of gene expression, but the functio
235 graphic rates, which in herbivores are often linked to resource-driven variation in body condition.
241 rtex (mPFC) for a subset of genes previously linked to social status revealed no differences between
242 of cosmic rays which are themselves directly linked to solar activity and the earth magnetic field.
243 y of which whose presence in blood is likely linked to specific cell-level pathologic processes.
244 cattle breeds significantly overlap regions linked to stature in human genetic studies, with a dispr
246 vely, our data suggest that mTOR activity is linked to T-bet in Ag-expCD4(+) T cells but that reducti
247 e incorporating a protonated hydrazone motif linked to the 1,2,5-oxadiazole 2-oxide subunit was synth
248 he women who met the inclusion criteria were linked to the data of their offspring contained within t
249 ed high wear resistance and low friction are linked to the formation of an ultra-nanocrystalline near
250 g the UK Clinical Practice Research Datalink linked to the Hospital Episode Statistics and Office for
251 overexpression of different efflux pumps is linked to the impairment of the quorum sensing (QS) resp
252 gates, suggesting that fibril disassembly is linked to the increased rate of peptidyl-prolyl isomeris
253 e snow accumulation (+50% at Dasuopu) likely linked to the meridional displacement of the winter west
254 The impact of cooking methods seemed mainly linked to the moisture loss increasing meat fat content
255 on; many of these regions have been directly linked to the neurobiology of pair bonding in monogamous
256 icantly from summer towards autumn, possibly linked to the ocean freeze-up and a seasonal rise in ozo
258 ttacks on prejudiced attitudes toward groups linked to the perpetrators as the cause of this increase
259 that are at least partially mechanistically linked to the powerful BDNF-TrkB neurotrophic signaling
261 infections against cancer has been recently linked to the production of acquired immunity effectors
262 lysis revealed that the antitumor effect was linked to the reduction in molecular vinculin-linked mol
264 cells and monocytes, respectively, which was linked to the severity of monocyte subset alterations.
265 reas the other functions of Tof1 are closely linked to the stable interaction between Tof1 and its co
267 tworks associated with adaptive immunity was linked to the suppression of networks for tight junction
268 observed for dyads containing BP covalently linked to thymidine, the aim of this work is to investig
269 nzymatic regulators of biochemical reactions linked to transmethylation and polyamine metabolism.
270 st that lower insight into bodily signals is linked to urges to move the body, putatively by engender
273 a massive collapse of terrestrial ecosystems linked to volcanism-driven environmental change triggere
276 This disruption of synaptic connectivity is linked to working memory impairment and is specific to r
277 n is regulated by the movement of end-to-end-linked troponin-tropomyosin complexes over the thin fila
278 repressive DNA structure, whereupon long K48-linked ubiquitin chains are conjugated to CMG-Mcm7, depe
279 nds Lys(11)-, Lys(48)-, Lys(63)-, and Met(1)-linked ubiquitin chains in vitro, establishing UBA(Cez)
280 lates cellular homeostasis by inhibiting K63-linked ubiquitination of beclin 1 mediated by TRAF2, cIA
282 ales act as resonant (5) unit cells that are linked via a shared wing membrane to form this metamater
283 cDNA) requires the removal of the covalently linked viral polymerase from the 5' end of the minus str
284 neat samples, although important differences linked with adduct formation in high-salt conditions exp
286 and triglycerides are likely to be causally linked with depression, so could be targets for treatmen
287 t Si-governed mitigation of Buta toxicity is linked with favorable modifications in energy flux param
288 unity-wide and within-patient microbiota are linked with inflammation, but we find no evidence for a
289 The greater complexity of eukaryotes is linked with larger genomes and we demonstrate that the b
292 amage and metabolic disorders are intimately linked with premature disease onset but the underlying m
293 Health risks from sitting are generally linked with reduced levels of muscle contractions in cha
294 Clinical Practice Research Datalink (CPRD), linked with secondary healthcare and mortality data, to
295 d with the subsequent stage) if the approach linked with the current stage proves to be unfeasible, a
296 stic outcomes of many cancer types have been linked with the expression levels of several of these ar
297 nfections occurred across the UK ICU network linked with the first few years of a national infection
298 riations in the TLR10/1/6 locus appear to be linked with the risk of contracting a bloodstream infect
300 Chromothripsis-related rearrangements were linked with univocal mutational signatures, with cluster