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1 is Rv3775 (LipE) was annotated as a putative lipase.
2 r cholesterol esters are cleaved off by acid lipase.
3 ion of the oral phase and the use of gastric lipase.
4 tion of endocannabinoids by monoacylglycerol lipase.
5 cterial genera and the activity of exoenzyme lipase.
6 Candida antartica lipase B, and Mucor miehei lipase.
7 ene PLIP1, which encodes a plastid-localized lipase.
8 g than quinoa, especially against pancreatic lipase.
9 ch as Streptomyces chromofuscus PLD or serum lipase.
10 hanase with a conserved domain of family I.3 lipase.
11 se in structural dynamics of the immobilized lipase.
12 enerated the same kind of inhibitors against lipase.
13 s and glycerol through the action of neutral lipases.
14 ere studied using exogenous or overexpressed lipases.
15 modifications by kinases, phosphatases, and lipases.
16 n enol ester link and tested against several lipases.
17 for NAPE-PLD versus other tissue-associated lipases.
19 ive Hnf4 signaling leads to up-regulation of lipase 3 and enzymes for mitochondrial beta-oxidation.
21 ivolumab and ipilimumab group were increased lipase (57 [10%] of 547), increased amylase (31 [6%]), a
23 ition tests of alpha-glucosidase, pancreatic lipase, acetylcholinesterase and 15-lipoxygenase were pe
24 and ABHD5 ligands, demonstrating that ABHD5 lipase activation could be dissociated from its other fu
25 ctivity for Nape-pld compared with nontarget lipase activities such as Streptomyces chromofuscus PLD
26 anced protease and alpha-amylase and reduced lipase activities were observed in sprouted oat powder,
27 sorder that is caused by loss of lipoprotein lipase activity and characterized by chylomicronemia and
28 The fungal infection significantly reduced lipase activity and lipid mobilization, thus impairing t
29 shows that water molecules essential for the lipase activity can be replaced by the hydroxyl groups a
30 free fatty acids and attenuated lipoprotein lipase activity consistent with hallmarks of dyslipidemi
36 It is concluded that polyurethanase with lipase activity represents a potential enzyme for the de
37 ongenital ichthyoses; and (v) lipoxygenases, lipase activity, and LIPN co-localize within putative la
38 h suppressed Gbeta expression exhibit higher lipase activity, and show phenotypes similar to plants o
39 ike protein 3 (ANGPTL3) inhibits lipoprotein lipase activity, increasing triglycerides and other lipi
41 showed the highest cellulase and the lowest lipase activity, while C. noveboracense had the highest
46 of the hydrolytic enzymes alpha-amylase and lipase along with stored food reserves (lipids, carbohyd
47 -specific phospholipase C and diacylglycerol lipase alpha is known, alternative pathways remain unset
49 r pharmacologic inhibition of diacylglycerol lipase-alpha (DAGL-alpha) impairs hippocampal CA1 LTP, d
51 l the extracts showed inhibitory activity of lipase, although those from T. molitor and extracted by
56 fied that the mutant strain lost most of its lipase and esterase activities and displayed reduced vir
57 thers without DM (n = 18), were analysed for lipase and fatty acid transport proteins and fatty acid
59 ere assessed on the inhibition of pancreatic lipase and interference on the bioaccessibility of chole
60 Our data suggest that LipE functions as a lipase and is important for M. tuberculosis intracellula
61 ignaling mediated by a LIPL-4 lysosomal acid lipase and its lipid chaperone LBP-8 increases mitochond
64 gas to nitrogen, the residual activities of lipase and lipoxygenase after the same time of atmospher
65 rgon as plasma gas, the residual activity of lipase and lipoxygenase decreased to 42.50% and 87.72%,
66 on in activity of fat destabilizing enzymes (lipase and lipoxygenase), contaminants heavy metals (As,
67 ited along with the lipid degrading enzymes, lipase and lipoxygenase, resulting in a relatively short
68 FCS); a deficiency in the enzyme lipoprotein lipase and some associated proteins, termed familial chy
69 iocatalytic approaches based on the use of a lipase and transaminase, respectively, the combination o
72 ydrolyze host lipid substrates with secreted lipases and phospholipases for nutrient acquisition, col
73 elated with the expression of the identified lipases and their lipase activity in a time-dependent ma
74 pha-amylase, -alpha-glucosidase, -pancreatic lipase) and antioxidant potential (FRAP, ORAC), phenolic
76 sociated perilipins 2/3/5, hormone-sensitive lipase, and 1-acylglycerol-3-phosphate O-acyltransferase
77 atty acids were hydrolyzed by Candida rugosa lipase, and more selectivity is observed with Porcine Pa
78 three different classes of enzymes (amylase, lipase, and sulfatase), relying on two distinct mechanis
79 gically assessed amylase, insulin, glucagon, lipase, and/or trypsinogen in 78 organ donor pancreata f
80 ous downstream molecules, including kinases, lipases, and linkers, is crucial for B cell selection, s
81 rt and metabolism-related genes (lipoprotein lipase, apolipoprotein A1, apolipoprotein A4, apolipopro
87 in and hederacoside C slightly inhibited the lipase (around 10%) and protodioscin reduced the bioacce
88 g fatty acid uptake and identify lipoprotein lipase as a potential therapeutic target in melanoma.
89 sing four commercially available immobilized lipases as catalysts and two acyl donors: ferulic acid (
90 via activation of the conserved triglyceride lipase ATGL-1, triggers a feedback transcriptional loop
91 through repressing the adipose triglyceride lipase (ATGL) activity in neutrophils in prostaglandin E
94 red lipolysis in global adipose triglyceride lipase (ATGL) knockout mice reduced free PAHSA levels an
95 of the lipolysis enzyme adipose triglyceride lipase (ATGL) resulted in large cytoplasmic LDs, whereas
96 ehydrogenase (POX), and adipose triglyceride lipase (ATGL), as well as markedly reduced lipid droplet
98 a specific inhibitor of adipose triglyceride lipase (ATGL), the rate-limiting enzyme for intracellula
99 conserved regulator of adipose triglyceride lipase (ATGL)-mediated lipolysis that plays important ro
101 y metabolic regulators, adipose triglyceride lipase (ATGL/bmm) and transcriptional cofactor PGC-1.
104 d using tert-butanol as a solvent, 20 g/L of lipase B from Candida Antarctica, and vinyl cinnamate as
106 ally available food-grade Candida antarctica lipase B, Lipozyme(R) 435, was used as the biocatalyst.
108 ty acid conjugate using a Candida antarctica lipase B-rich extract, without further purification and
110 oth sexes identified a role for triglyceride lipase brummer (bmm) in the regulation of sex difference
115 y extension Ras, allosterically activate the lipase by promoting and stabilizing interactions between
116 increased HDL levels (P = 7.7 x 10(-7)), but lipase C risk variants (rs2043085, rs2070895) were assoc
118 into egg-yolk phosphatidylcholine (PC) in a lipase-catalyzed acidolysis and interesterification proc
120 e 4-carboxyindanone followed by a subsequent lipase-catalyzed resolution turned out to be the most ef
121 ted protein 2 (PNLIPRP2), and carboxyl ester lipase (CEL), which may leak into the visceral fat or sy
123 Herein, we prepare aqueous suspensions of lipase-coated oil globules comprising a mixture of a tri
124 ibition of alpha-glucosidase, alpha-amylase, lipase, cyclooxygenases-1 and -2 (COX-1/COX-2), and lipo
129 d extracted chia seed oil and with different lipase derivatives to compare the omega-3 FAEE yield and
132 e functions that extends from the N-terminal lipase domains to the C-terminal EDS1-PAD4 domains and m
137 ter adverse events related to treatment were lipase elevation (n = 7 [10.8%]), fatigue (n = 4 [6.2%])
138 s occurred in 12 (29%) patients and included lipase elevation, atrial fibrillation, hypophosphataemia
139 e D (PLD), a ubiquitously expressed membrane lipase enzyme activity in modulating phagocyte functions
141 nce shares similarities with other bacterial lipase/esterases and we demonstrated that it has esteras
142 e active sites of 43 active SHs encompassing lipases/esterases, GDSL lipases, proteases, Ser carboxyp
145 identified a gene encoding a novel class III lipase family member, Sl-LIP8, that is associated with a
148 ught to purify, identify, and characterize a lipase from S. liquefaciens isolated from cold raw cow's
153 RNA level of hexokinase-2, hormone sensitive lipase, glutathione peroxidase-1, and myosin heavy chain
155 sp catalytic triad, a highly active cysteine-lipase having a Cys-His-Asp catalytic triad and addition
158 ance of lipid droplets and hormone-sensitive lipase (HSL) in regulating the aggressive nature of panc
159 atty acid synthase (FASN), hormone-sensitive lipase (HSL), and acyl dehydrogenases was analyzed in vi
160 f LD through regulation of hormone-sensitive lipase (HSL), which was downregulated in human PDAC.
170 reatment-related adverse event was increased lipase in the durvalumab group (seven [2%] of 345 patien
174 focus on specific functions of intracellular lipases in lipid partitioning, covering basic and transl
175 orophosphonate-binding serine hydrolases and lipases in S. aureus and synthesized target-selective ac
177 ein profiling approach to unravel the active lipases, including other Serine hydrolases (SHs), expres
178 ents in the ripretinib group (n=85) included lipase increase (four [5%]), hypertension (three [4%]),
180 or worse treatment-related adverse event was lipase increase, which occurred in 14 (4%) of 353 patien
181 otransferase increased (33.9% vs 22.8%), and lipase increased (32.2% vs 27.4%); 13% of patients in th
187 eir functional roles and substrates, the pan-lipase inhibitor isopropyl dodecylfluorophosphonate was
188 overed the repeated loss of the triglyceride lipase inhibitor PNLIPRP1, suggesting enhanced triglycer
189 tat measurements in presence of a pancreatic lipase inhibitor proved to be an efficient way to widen
190 administration of JZL184, a monoacylglycerol lipase inhibitor, blocked SI deficits associated with in
192 erine hydrolases by using a panel of neutral lipase inhibitors to identify an enzyme that reacts pote
197 investigated the possibility that S. aureus lipases interface with the host immune system to blunt i
198 the activity of hepatic adipose triglyceride lipase, intrahepatic lipolysis, hepatic acetyl-CoA conte
200 st by immobilization of Candida antarctica B lipase is reported, coating single-core magnetic nanopar
201 ound that VPA0226, a constitutively secreted lipase, is required for escape of V. parahaemolyticus fr
202 been reported to allosterically activate the lipase, it is not known whether Rap1A has the same abili
203 ular dichroism measurement confirms that the lipase keeps its native conformation in the aerogel, and
205 y that simultaneously monitors two high risk lipases known to impact biologics product quality, Phosp
206 e and day 3 compliance with triglyceride and lipase laboratory monitoring per protocol and time to di
209 zation, the metabolic role of lysosomal acid lipase (LAL), highly expressed in adipocytes, is unclear
211 ce protocol compliance with triglyceride and lipase level monitoring and mitigate propofol-related ha
212 ormal range, 30-130 U/L [0.5-2.2 ukat/L]), a lipase level of 172 U/L (2.9 ukat/L) (normal range, 0-60
220 (allele frequency=0.36), mapping to hepatic lipase (LIPC), to be associated with a smaller increase
223 des, markers of lipogenesis, and lipoprotein lipase (LPL) activity in adults participating in a doubl
224 anged in ppHF dams, but systemic lipoprotein lipase (LPL) activity was increased, suggesting that inc
235 Using RNA in situ hybridization, lipoprotein lipase (LPL) was found to be expressed in endothelial ce
236 pillary endothelial cells, binds lipoprotein lipase (LPL) within the subendothelial spaces and shuttl
237 rexpression of the gene encoding lipoprotein lipase (LPL), which was upregulated in zebrafish melanoc
238 bition (DSI) was limited by monoacylglycerol lipase (MAGL) but not by fatty acid amide hydrolase.
239 ith regional differences in monoacylglycerol lipase (MAGL) expression in postmortem brain tissue, suc
241 ve focused on inhibition of monoacylglycerol lipase (MAGL) to enhance signaling of the most abundant
242 ies of tetrazine probes for monoacylglycerol lipase (MAGL) were synthesized and the most reactive one
244 nt actions of inhibitors of monoacylglycerol lipase (MAGL), the major degradative enzyme of the endoc
245 ional target MGLL, encoding monoacylglycerol lipase (MAGL), to regulate the self-renewal and tumorige
247 n 1 (GPIHBP1) and with its chaperone protein lipase maturation factor 1 (LMF1), we obtained a stable
250 t (HFD)-induced obesity for monoacylglycerol lipase (MGL), an enzyme that is also known to hydrolyze
252 at are potent inhibitors of monoacylglycerol lipase (MGL), the primary degrading enzyme for the endoc
254 al-specific knockout of adipose triglyceride lipase not only reduced fetal beta-cell area and blood i
255 determinants such as exoenzymes (proteases, lipases, nucleases) and downregulate the expression of s
256 nity were not due to direct functions of the lipase on mammalian cells, but rather a result of inacti
257 aminotranferases (one [2%] of 46), increased lipase or amylase (two [4%]), and pancreatitis (one [2%]
259 High glucose levels did not alter placental lipase or transporter expression or the profile and abun
261 , CEE extracts being stronger (fenugreek for lipase -p = 0.009-, and quinoa for alpha-amylase -p < 0.
263 ity lipoprotein cholesterol, the lipoprotein lipase pathway or circulating lipoprotein(a) may be effi
266 ancreas expresses pancreatic triacylglycerol lipase (PNLIP), pancreatic lipase-related protein 2 (PNL
267 se in apparent activity than the lyophilized lipase powder in transesterification of geraniol and vin
268 oteins, lactoferrin and bile salt-stimulated lipase, presented different kinetics of release during d
269 that the Geh lipase, but not other S. aureus lipases, prevents activation of innate cells in culture.
270 ive SHs encompassing lipases/esterases, GDSL lipases, proteases, Ser carboxypeptidases, ABHD protein,
271 mpathectomy and loss of adipose triglyceride lipase protect mice from GDF15-induced weight loss.
274 rol/triacylglycerol ratio of 3/1, 9.0% (w/w) Lipase PS-DI, a stirring rate of 200 rpm, and a reaction
276 c triacylglycerol lipase (PNLIP), pancreatic lipase-related protein 2 (PNLIPRP2), and carboxyl ester
279 Staphylococcus aureus secretes at least two lipases, Sal1 and glycerol ester hydrolase (Geh), with s
285 , with sequence similarity to plant esterase/lipase/thioesterase (ELT) proteins, is essential for tri
286 atment-related adverse events were increased lipase (three [7%]) and febrile neutropenia (three [7%])
290 Here, we showed that the stabilization of lipase upon MPCI to polymer brush surfaces resulted from
291 il catalysed by polyethylene glycol-modified lipases using a biocatalyst with higher stability than c
292 r shrimp fed diets 3 and 7, while intestinal lipase was significantly higher in shrimp fed diets 7 an
295 upon enzymatic activity and are selective to lipases were developed under the name of shifting-nitrox
298 n of the putative effector indicates it is a lipase, which we name TleV1 (type VI lipase effector Vib
299 of pancreatic disease and normal amylase and lipase who underwent the examination with the same proto
300 of this method is demonstrated for two other lipases with different structures, promising unprecedent