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1 s are formed from their corresponding diacyl lipids.
2 he integrated roles of ATP6AP1, glycans, and lipids.
3 on precursor for polyphosphoinositide (PPIn) lipids.
4 rst time among the minor components of these lipids.
5 s, constituting up to 50% of plasma membrane lipids.
6 intestinal tract to aid in the absorption of lipids.
7 r levels of alpha-tocopherol (6.7 mg/100 g), lipids (23.11 g/100 g, manly oleic and linoleic acids),
8 e-glycine dipeptide lipid classes, including lipid 430 and lipid 654, are produced by the periodontal
9 ptide lipid classes, including lipid 430 and lipid 654, are produced by the periodontal pathogen Porp
11 stis mutant synthesizing an adjuvant form of lipid A (monophosphoryl lipid A, MPLA) displayed increas
12 rocrystalline tyrosine (MCT), monophosphoryl lipid A (MPLA) and calcium phosphate (CaP) used less fre
13 Addition of a C16 fatty acid (palmitate) to lipid A by the outer membrane acyltransferase enzyme Pag
14 e death as a result of septic shock, and its lipid A core is the target of polymyxin antibiotics(3,4)
15 phism to the sequence present in Ypt and Ye, lipid A isolated from a Yp pagP+ strain synthesized two
16 an adjuvant form of lipid A (monophosphoryl lipid A, MPLA) displayed increased biogenesis of bacteri
20 multisubunit protein machines extract these lipids after their synthesis is completed at the inner m
25 aque phenotype characterized by an increased lipid and macrophage content, plaque size, and pro-infla
26 me had no effect (P > 0.05) on dry-aged beef lipid and protein oxidative stabilities and proteolysis
29 eriority of COOH-NHMe (IV) in detecting more lipid and protein species compared to commercially avail
30 lyses revealed a marked reduction in storage lipids and an increase in membrane phospholipids, sugges
33 ts were observed, elevated levels of neutral lipids and phospholipids resemble previously reported ef
34 The higher oxygenation altered methionine, lipid, and purine metabolism, and inhibited quiescence,
35 nelline, formic acid, hydroxymethylfurfural, lipids, and gamma-butyrolactone also contributed to scor
36 case that spectral measurements of proteins, lipids, and glucose in the short-wavelength IR region, p
37 of the scavenger receptor CD36, accumulated lipids, and used fatty acid oxidation (FAO) instead of g
39 A hallmark of AMD is the overproduction of lipid- and protein-rich extracellular deposits that accu
40 natural variability range for most meibomian lipids (app. +/- 15% of the Mean), these differences in
49 detergent-based protocol for scrambling the lipid asymmetry of liposomes and maybe cells without com
52 oscopy, the 3D configuration of proteins and lipids at intermediate steps can only be resolved with c
54 tions to maximise protein integration into a lipid bilayer and the oligomerisation of the protein int
56 e BsYetJ (or TMBIM6) structure embedded in a lipid bilayer is uncharacterized, let alone the molecula
57 (4)) or greigite (Fe(3)S(4)), enveloped by a lipid bilayer membrane, produced by magnetotactic bacter
58 ies effect originates from a looser swelling lipid bilayer structure due to the adsorption and electr
59 eptor SpA was attached to BioPE-DOTAP binary lipid bilayer tethered on alkane thiol molecular cushion
60 ristics of transient pores on a patch of the lipid bilayer that is strengthened by an elastic meshwor
62 nd exhibit selective proton transport across lipid bilayers at a rate similar to those of natural pro
63 ingle-channel electrical recording in planar lipid bilayers in conjunction with protein engineering,
68 re we report that, in mammalian cells, NF2's lipid-binding ability is critical for its function in ac
69 we suggest how changes in the association of lipid-binding caveolar proteins upon flattening of caveo
72 scovered that Fabp5, an abundant cytoplasmic lipid-binding protein found in brain endothelial cells,
76 mic reticulum (ER), the main cellular hub of lipid biosynthesis and the entry site for the secretory
77 A), 2-monoacylglycerol (2-MAG), and membrane lipid biosynthesis and transport during nodule developme
78 il composition involve the overexpression of lipid biosynthetic enzymes, but how these enzymes are as
79 hese measurements suggest that Zn(2+) caused lipid blebbing by decreasing the area per lipid on the s
82 t, we demonstrated that genetic induction of lipid cacostasis in the CNS of normal mice was associate
83 on of a 1:1 protein-lipid complex, where the lipid cannot be displaced by detergent from the highly p
85 re downregulated while those associated with lipid catabolism and chitin turnover were significantly
86 These results indicate that AHL4 suppresses lipid catabolism by repressing the expression of specifi
89 h protonated ions of the species of the same lipid class with two additional CH(2) and three double b
90 ation of authentic standards belonging to 12 lipid classes and helps to assign 133/58 lipid features
91 hingolipids (notably GM(3) gangliosides) and lipid classes previously associated with cardiometabolic
93 r CCS and HILIC retention time for 22 and 23 lipid classes, respectively, were trained using the larg
94 y assembles with lipid vesicles into peptide/lipid coaggregates that resemble amyloid fibrils in some
95 II results in the formation of a 1:1 protein-lipid complex, where the lipid cannot be displaced by de
97 ds, and low-molecular-weight metabolites; 98 lipid composition and particle concentration measures of
101 ososomes were constructed by rosmarinic acid-lipid conjugates which not only work synergistically wit
102 enriched batches or affect the moisture and lipid content during processing and/or culinary cooking.
103 The results show that while total neutral lipid content was unchanged relative to age-matched cont
107 mmation and remarkably blocked the increased lipid deposition and the atherogenic gene expression in
108 V1 worms with low levels of phosphoinositide lipids display an enhanced response to capsaicin, wherea
109 mitochondrial alanine metabolism to membrane lipid diversity, which further sensitizes tumours to met
117 ct that TGs and SEs are the typical cargo of lipid droplets suggests that these organelles could be c
120 dynamics of lipid-lipid, lipid-protein, and lipid-dye interactions with single-molecule, nanoscale r
122 ty to RAS and with RBD causing local anionic lipid enrichment that enhances the overall affinity betw
125 phyromonas gingivalis and can be detected in lipid extracts of diseased periodontal tissues and teeth
127 latform provided 230 metabolite measures: 51 lipids, fatty acids, and low-molecular-weight metabolite
128 12 lipid classes and helps to assign 133/58 lipid features in positive-/negative-ion mode from mouse
131 by using summary-level data from the Global Lipid Genetics Consortium (n = 188,577) and UK Biobank C
132 , height, weight, waist circumference, blood lipids, glucose, insulin, and blood pressure were measur
134 strated fluctuations in correlations between lipid groups at M1, M3, and CB, signifying differences i
137 interaction between the fluorophores and the lipid headgroups facilitates the initial, fast membrane
143 or their inhibition against the formation of lipid hydroperoxides and carbonyl compounds in a strippe
144 erry press cake remarkably reduced levels of lipid hydroperoxides, malondialdehyde (MDA) and 4-hydrox
145 find that addition of the natural substrate lipid-II results in the formation of a 1:1 protein-lipid
146 eviously identified B. burgdorferi proteins, lipid immunogens, and live mutants lead the design of ca
148 as found to dramatically reduce the area per lipid in lipid monolayers, while Mg(2+) and Cu(2+) did n
151 To enhance our understanding of the role of lipids in regulation of lifespan and healthspan addition
155 erved transporter of mycolic acid-containing lipids including monomeromycolyl diacylglycerol (MMDAG),
157 uctural characterization by CryoEM reveals a lipid-induced stabilization to the channel, resulting in
159 establish a mechanistic understanding of LBL-lipid interactions and create a modified BoNT/B with imp
163 f concept, in situ separation and imaging of lipid isomers with distinct spatial distributions were p
165 al benefits of statin use in PWH with normal lipid levels requires further clinical outcome research.
167 strong enrichment with typical mitochondrial lipids like cardiolipins and demonstrated the presence o
169 development of synthetic membranes to study lipid-lipid interactions in vitro, alongside optical mic
170 he organizational and functional dynamics of lipid-lipid, lipid-protein, and lipid-dye interactions w
171 aphy and quantitatively analyzed periprotein lipids located within the diameter defined by one SMALP.
173 eventive pharmacotherapies, such as aspirin, lipid-lowering mediations, and cardiometabolic agents.
174 criteria for intensive secondary prevention lipid-lowering therapy (28.3% vs. 40.0% vs. 81.4%, respe
177 0 to 17 years of age who had received stable lipid-lowering treatment for at least 4 weeks before scr
178 er, our results establish that the bioactive lipid LPA drives the expression of TNF-alpha to regulate
182 l characterization, structures of TRPV3 in a lipid membrane environment provide unique insights into
184 d step occurring over many days where native lipid membranes assemble into well-defined multilayer st
185 ined multilayer structures, whereas diseased lipid membranes form folded assemblies with high local c
187 ") of lipophilic probes transiently bound to lipid membranes, revealing that Nile red's (NR) orientat
196 a large number of molecules associated with lipid metabolism are known to be implicated in MNDs, the
197 genome sequences reveals photosynthesis and lipid metabolism are preferentially retained after a rec
198 estigate the role of fructose in glucose and lipid metabolism in the liver, heart, skeletal muscle, a
201 s have the potential to rebalance disordered lipid metabolism, leading to improvements in nonalcoholi
202 meostasis and metabolic activities involving lipid metabolism, specifically the synthesis of pigments
207 MTG content while minimising accumulation of lipid metabolites known to disrupt skeletal muscle insul
208 rt IMTG storage and minimise accumulation of lipid metabolites to protect skeletal muscle insulin sig
210 rticle IAV lipid mixing, whereas the rate of lipid mixing is independent of cholesterol composition.
211 pids within the membrane, yet the effects of lipid mixing on the membrane biophysical properties rema
212 hances the efficiency of single-particle IAV lipid mixing, whereas the rate of lipid mixing is indepe
214 ng nuclear localized (AHL) protein regulates lipid mobilization and fatty acid beta-oxidation during
216 toylation is a reversible post-translational lipid modification that dynamically regulates protein fu
217 containing an NGL consisting of the optimal lipid moiety and the GM1 ganglioside pentasaccharide yie
222 in (lacking AD-3) with squalene adjuvant, or lipid nanoparticle (LNP)-encapsulated nucleoside-modifie
226 ed lipid blebbing by decreasing the area per lipid on the side of the bilayer to which the salt was e
228 ce of the identified compounds and indicated lipid oxidation and the Maillard were the reaction pathw
229 ry press cake (called "helpers") to minimize lipid oxidation during acid/alkaline pH-shift protein is
232 for microbial count, chemical stability (pH, lipid oxidation, lipolysis), and optical properties.
234 he membrane diffusivity drops with increased lipid packing order when comparing the endoplasmic retic
237 of normal mice was associated with ALS-like lipid pathology, astrogliosis, neurodegeneration, and cl
238 es associated with prevalent AD arising from lipid pathways including; ether lipids, sphingolipids (n
239 ung IR increased the tissue iron content and lipid peroxidation accumulation, along with key protein
240 al, we found high consistency in measures of lipid peroxidation and circulating non-enzymatic antioxi
241 d by 4-hydroxynonenal ([4HNE] a byproduct of lipid peroxidation) on mitochondrial function and struct
243 ve summary of fundamental concepts regarding lipid peroxidation, experimental tools for the study of
245 dies with PTEN mutants that lack only PTEN's lipid phosphatase activity or both PTEN's lipid and prot
246 s multiple interactions with plasma membrane lipids: Phosphatidylinositol (4, 5)-bisphosphate (PIP(2)
249 to explore the associations between maternal lipid profile and small-for-gestational-age neonates.
250 population, the effect of Adv36 infection on lipid profile varied between healthy individuals and ind
253 lecular dynamics simulations, we explore the lipid-protein interaction profiles of 28 different GPCRs
254 onal and functional dynamics of lipid-lipid, lipid-protein, and lipid-dye interactions with single-mo
255 ulted in the defective expression of over 60 lipid-raft-associated surface receptors, and impaired BC
256 n of neuronal cholesterol trafficking and of lipid rafts by Nef may contribute to early stages of neu
259 attachment of carbohydrates to proteins and lipids, regulates nearly all cellular processes and is c
260 rrow-derived macrophages, heme induced HO-1, lipid regulatory genes including LXR (lipid X receptor),
261 ipid groups are known, the enzymes mediating lipid removal (i.e. deacylation) are largely unknown.
266 results are consistent with NAE 18:3 being a lipid signaling molecule in plants with a requirement fo
267 ) activates the channel; a secondary anionic lipid site has been identified, which augments the activ
269 aracterized by an asymmetric distribution of lipid species across the exofacial and cytofacial aspect
270 arising from lipid pathways including; ether lipids, sphingolipids (notably GM(3) gangliosides) and l
273 Abeta oligomers, which reveal how they form lipid-stabilized pores that might disrupt neuronal membr
274 ic medium induced a significant increment of lipid storage in ccRCC cells that had a low 36-kDa AnxA3
279 A decrease in the total levels of complex lipids such as phosphatidylethanolamines (PE), lactosylc
280 esicles that also contain background anionic lipids such as phosphatidylserine but much weaker when e
281 ponse to capsaicin, whereas phosphoinositide lipid supplementation reduces TRPV1-mediated responses.
283 of terminal differentiation (FLG and FLG2), lipid synthesis/metabolism (ELOVL3 and FA2H), and tight
284 embrane led to a local enrichment of anionic lipids that could potentially enhance the membrane affin
285 f phosphatidylinositol 4,5-bisphosphate-like lipids that induce a directional membrane-mediated inter
286 e phosphatidylinositol 4,5-bisphosphate-like lipids that preferentially interact with the charged end
288 ic variation in the maternal provisioning of lipids to offspring, with a positive correlation between
291 ial challenge, as exemplified by the case of lipid transfer polyproteins, which are common pollen all
292 enotypic switch to oxidative metabolism with lipid utilization to fuel invasion and metastasis occurs
293 AP(248-286) much more readily assembles with lipid vesicles into peptide/lipid coaggregates that rese
294 nity of HuNoV virus-like particles (VLPs) to lipid vesicles produced from the individual HIE-lipid ex
295 low nanomolar apparent affinity to PIP(2) in lipid vesicles that also contain background anionic lipi
298 (ATCC 33277) was grown in broth culture, and lipids were extracted and fractionated by high-performan
299 edged to depend on the unique composition of lipids within the membrane, yet the effects of lipid mix
300 HO-1, lipid regulatory genes including LXR (lipid X receptor), the growth factor IGF1 (insulin-like