ライフサイエンスコーパス: lipid composition

1 raction of a peptide with membranes of mixed lipid composition.

2 r, when reconstituted in vesicles of defined lipid composition.

3 ponsive to post-assembly changes in membrane lipid composition.

4 artitioning to membrane domains of different lipid composition.

5 ies point to P limitation-induced changes in lipid composition.

6 infectivity involves alterations of membrane lipid composition.

7 in granular layers and significantly altered lipid composition.

8 dynamically driven, and the yield depends on lipid composition.

9 is difficult to manipulate cellular membrane lipid composition.

10 limate, can be observed in terms of membrane lipid composition.

11 rt vesicles according to their size and bulk lipid composition.

12 splayed subtle but consistent differences in lipid composition.

13 loid-beta protein, on membrane thickness and lipid composition.

14 ide the complexity and diversity of membrane lipid composition.

15 mbrane space, only in the vicinity of native lipid composition.

16 s to achieve this can be heavily affected by lipid composition.

17 ns at membrane interfaces through changes in lipid composition.

18 n caveolae and their ability to sense the PM lipid composition.

19 llowing a threshold change in proteoliposome lipid composition.

20 pids triggered by a change in proteoliposome lipid composition.

21 es to enhance curvature and affect the local lipid composition.

22 by the peptide:lipid (P:L) ratio and by the lipid composition.

23 characterized by differences in protein and lipid composition.

24 tissues based on changes in detected neutral lipid composition.

25 ilayer can be largely determined by membrane lipid composition.

26 1 (MCC) and Pma1 (MCP), which have different lipid compositions.

27 scale dimensions of membranes with different lipid compositions.

28 ctivated protein C to seven different binary lipid compositions.

29 influenza virus and vesicles with a range of lipid compositions.

30 ry structure of bR in nanodiscs of different lipid compositions.

31 membrane function requires distinct leaflet lipid compositions.

32 to the affinity for physiologically relevant lipid compositions.

33 orophores into lipid bilayers with different lipid compositions.

34 cretion [15], organized in part by the local lipid composition [16].

35 proteoliposomes: 1) optimization of desired lipid composition, 2) detergent-mediated protein reconst

36 The human brain shows the most distinct lipid composition: 76% of 5,713 lipid compounds examined

37 Altered cellular lipid composition activates the endoplasmic reticulum un

38 The mechanisms by which these changes in lipid composition affect cellular function and ultimatel

39 Several unexpected changes in lipid composition also occur in regions where the NPSCs

40 ore, we show that KIFs control mitochondrial lipid composition and activity in a cell-intrinsic manne

41 118 different lipids suggests that membrane lipid composition and adaptation mechanisms in Thaumarch

42 Structural data indicate that the lipid composition and bilayer structure are likely to ha

43 eral organization demonstrates dependence on lipid composition and bilayer thickness.

44 es and their effects on membranes that mimic lipid composition and biophysical properties of the vira

45 The LAURDAN spectrum is sensitive to the lipid composition and dipolar relaxation arising from wa

46 owever little knowledge, if any, about their lipid composition and dynamics.

47 estigated only a single clotting protein and lipid composition and have yielded widely different bind

48 Hepatic lipid composition and histopathology revealed that devel

49 rol was used to investigate the influence of lipid composition and lipid asymmetry upon the conformat

50 o cytoplasmic myelin membranes with modified lipid composition and low MBP concentration, as in demye

51 innate immune signaling, affecting cellular lipid composition and membrane fluidity.

52 lipid vesicles of various sizes, as well as lipid composition and membrane mechanical properties, we

53 How these protein clusters modify local lipid composition and membrane morphology is largely unk

54 ver, little is known about the regulation of lipid composition and organization in synaptic membranes

55 by SERINC5 does not depend on alterations in lipid composition and organization of HIV-1 particles an

56 hese results reveal developmental changes in lipid composition and palmitoylation that facilitate the

57 ds, and low-molecular-weight metabolites; 98 lipid composition and particle concentration measures of

58 structed arrays of Nanodiscs having variable lipid composition and probed the binding interactions of

59 for the first time the effect of changes in lipid composition and regulators of cellular processes.

60 nclusion, dietary lipids can modulate T cell lipid composition and responses in lipoprotein receptor

61 modulus, for lipidic assemblies of arbitrary lipid composition and shape, from molecular dynamics sim

62 g the main experimental conditions: liposome lipid composition and size to be similar to those of Dox

63 thermore, FASN contributes to correct myelin lipid composition and stability of myelinated axons.

64 ng lipoproteins by approximately 3-fold; the lipid composition and stoichiometry of these particles w

65 fraction (XDMSO) of <0.1, regardless of the lipid composition and the lipid phase.

66 otosensitizer to oxidize vesicles of various lipid compositions and degrees of unsaturation in a cont

67 hat the method can be used with a variety of lipid compositions and probe the mechanism of templated

68 gle and multicomponent bilayers of different lipid compositions and sizes, simulated at different tem

69 rom the interplay between peptide structure, lipid composition, and cellular target membrane selectiv

70 the relationship between gas-phase behavior, lipid composition, and instrumental polarity was investi

71 imilarities, despite significantly different lipid composition, and interesting differences.

72 ugh there is strong evidence that in myelin, lipid composition, and lipid membrane morphology are aff

73 lation on morphology, protein incorporation, lipid composition, and membrane fusion.

74 GlpG, captured within three different native lipid compositions, and identify protein regions sensiti

75 for erythrocytes, as judged by outer leaflet lipid composition; and plasma membrane outer leaflet pho

76 react to and/or induce changes in shape and lipid composition are discussed here.

77 ulp, suggesting that the observed changes in lipid composition are due to diffusive rather than local

78 te that both structural tethers and a proper lipid composition are needed for ERTGoCS integrity.

79 s-sorting of flippases and remodeling of the lipid composition are the first occurring defects in GAR

80 omics was used to measure dynamic changes in lipid composition as a function of age and gender in gen

81 were found to exhibit a radically different lipid composition as compared to cultures in the exponen

82 DAN has the advantage to be sensitive to the lipid composition as well as to membrane fluidity.

83 Samples with similar lipid compositions as those of the fingerprints were col

84 agulation factor binding under physiological lipid compositions, as opposed to the artificially high

85 om 15 degrees C to 25 degrees C and membrane lipid composition assessed.

86 h extensibility was therefore related to its lipid composition at the start of mixing.

87 abeled supported lipid bilayers of different lipid compositions at mechanistically important pH condi

88 In summary, DESI-MSI identified distinct lipid composition between DCIS and IBC and across molecu

89 ealed, demonstrating significantly different lipid compositions between the various tissue types with

90 This most visibly manifests in a different lipid composition, but it can also involve opposing late

91 In vivo remodeling of the mitochondrial lipid composition by lithocholic acid treatment or by ab

92 s of nuclear membranes we investigated their lipid composition by two quantitative methods, namely, (

93 These results imply that lipid composition can be a critical factor that affects

94 ctra in heterogeneous Nanodiscs and that the lipid composition can be determined by using a dual Four

95 r crowding, rather than changes in monolayer lipid composition, causes proteins to fall off the LD su

96 duced glycerol concentration, and changes to lipid composition compared with the wild type, including

97 The thylakoid membrane has a unique lipid composition, consisting mostly of galactolipids.

98 An enormous complexity in lipid composition could be revealed.

99 embranes, many factors such as cytoskeleton, lipid composition, crowding, and molecular interactions

100 ystems to living cell membranes with complex lipid compositions, cytoskeletal attachment, and membran

101 Changes in lipid composition decrease membrane fluidity, F(0)F(1)-A

102 To study the lipid-composition dependence of photocycle kinetics of b

103 that the P2X7 receptor itself constitutes a lipid-composition dependent dye-permeable pore, whose op

104 ial effects, the insulin:C-peptide ratio and lipid composition differ between EVs from healthy pancre

105 tive abundances of these IPLs and their core lipid compositions differ systematically between the phy

106 These changes in lipid composition due to different enzyme activity are s

107 The determination of the lipid composition during an LCD enables the identificati

108 We evaluated the changes in lipid composition during weight loss and their associati

109 n orientation can only partially explain the lipid composition effect on transport rate.

110 over, the simulations also indicate that the lipid composition especially in terms of charged lipids

111 We produced two lines that had very similar lipid compositions except that one, ER-FAT5, contained h

112 itrations allowed measurement of the optimal lipid composition for the membrane protein.

113 3 SMALP-extracted proteins revealed distinct lipid compositions for each protein: ZipA and PgpB were

114 rms of signaling require a distinct membrane lipid composition, found at cilia.

115 ng from water penetration, but disentangling lipid composition from membrane fluidity can be obtained

116 MAT adipocyte development, regulation, size, lipid composition, gene expression and genetic determina

117 Changes to the SC lipid composition have been associated with barrier impa

118 Similar changes in lipid composition have been observed in marine photoauto

119 were closest to mammalian plasma membrane in lipid composition (i.e., with brain SM, POPC, and/or hig

120 DAC6 leads to significant age-dependent EFA, lipid composition imbalance, and reduced animal longevit

121 ens new avenues for metabolic engineering of lipid composition in algae.

122 ary alveolar proteinosis (PAP), we evaluated lipid composition in alveolar macrophages and lung surfa

123 sh that membrane homeostasis is regulated by lipid composition in Arabidopsis and reveal a mechanism

124 Lipid composition in breast cancer, a central marker of

125 fect on activation through the regulation of lipid composition in cell membranes.

126 The lipid composition in endosperm cells in A619 is altered,

127 beta-Catenin ASO altered hepatic lipid composition in high-fat-fed mice.

128 rated fatty acid (PUFA) desaturation and the lipid composition in human blood and tissue.

129 to delineate the role of FADSs in modulating lipid composition in human liver.

130 altering gene transcription and controlling lipid composition in human livers.

131 acterize the spatial and temporal changes in lipid composition in lung tissue.

132 nguishing the putative role(s) of the native lipid composition in modulating membrane protein conform

133 (PS) and DOPE (PE) to understand the role of lipid composition in MP1's anticancer characteristics.

134 IB-ToF-SIMS was used to elucidate changes in lipid composition in nine breast cancer biopsy samples.

135 The altered lipid composition in the circulation, and of T cells, wa

136 The impact of heat treatments on the lipid composition in the fish tissue seems to be species

137 different lipids and thus retains the native lipid composition in the solubilized particles.

138 his homeostatic circuit maintains a constant lipid composition in the trans-Golgi network and post-Go

139 n relative to the membrane normal and of the lipid composition in the vicinity of the bound peptide.

140 How membrane lipid composition in turn defines the functional space a

141 th anti-TNF-alpha siRNA cause changes to the lipid composition in white pulp regions of the spleen, a

142 This result indicates that the lipid compositions in one leaflet are strongly coupled t

143 opy, we have characterized phases of ternary lipid compositions in the presence of saturated phosphol

144 ecific microbial associations were found for lipid compositions in the VLDL, IDL, and LDL lipoprotein

145 55 is relatively insensitive to the membrane lipid composition, in agreement with experimental observ

146 LS is defined by a specific protein and lipid composition, including saturated and unsaturated p

147 d systems that describe these modulations in lipid composition indicate that the average stored curva

148 Analyses of lipid composition indicators confirmed a shift toward le

149 Host lipid composition influences many stages of the influenz

150 rane properties, demonstrating that membrane lipid composition is a biochemical control parameter and

151 l variations in the material stiffness do as lipid composition is changed.

152 se (UPR) exclusively when normal ER membrane lipid composition is compromised, we identified pathways

153 Their lipid composition is detailed here with special emphasis

154 n, previous knowledge of healthy lung tissue lipid composition is essential; however, these studies a

155 A regime of lipid composition is found where all properties are favo

156 Our results suggest that proper PM lipid composition is important to stabilize the central

157 r, how they induce and maintain their unique lipid composition is largely unknown.

158 The membrane lipid composition is tightly regulated by the cell, main

159 ns incorporated into nanodiscs of controlled lipid composition is used to obtain information on the l

160 studies observed that changes in the myelin lipid composition lead to instabilities and enhanced loc

161 apsulation of high refractive index markers, lipid composition, liposome size, and surface modificati

162 the evolutionary scale, changes in membrane lipid composition may necessitate extensive adaptation o

163 d T cell responses in vivo along with T cell lipid composition, membrane order, and activation ex viv

164 form domains in symmetric vesicles, and this lipid composition mimics plasma membranes to a significa

165 esiding in 60 nm unilamellar vesicles, whose lipid composition mimics the mammalian plasma membrane o

166 Here we report how changes in lipid composition modulate this insertion scheme.

167 in the dynamic regulation of cilia membrane lipid composition, morphology, and signaling protein con

168 PLTP absence drastically altered the lipid composition of apoB:1000 lipoproteins; these parti

169 The lipid composition of arteries in lung tissue samples fro

170 The heterogeneity of lipid composition of biological membranes and the effect

171 levated sphingolipid turnover and an altered lipid composition of both MAM and mitochondrial membrane

172 tics that target pathological changes in the lipid composition of cancerous cells.

173 The lipid composition of cell membranes has increasingly bee

174 es these lymphocytes to sense changes in the lipid composition of cells and tissues as a result of in

175 In this study, we analyzed lipid composition of Chamaecyparis obtusa extract, and w

176 scarcity of comparative data on the membrane lipid composition of cultivated representatives, includi

177 tolerogenic, induce different changes in the lipid composition of cultured CD11c(+) cells, and highli

178 as are capabilities to identify the complex lipid composition of different membranes, to probe the c

179 ailed analysis of the corresponding membrane lipid composition of differentiated cells was performed

180 ures, W10BSmL and WgmZOflL We determined the lipid composition of E. gracilis strain Z mitochondria a

181 The analyses revealed that the lipid composition of E3hom TPs was strikingly different

182 racilis middle plastid envelope based on the lipid composition of envelope fraction.

183 omes, suggesting that the unique protein and lipid composition of exosomes does not appreciably impac

184 , the effect of this culture approach on the lipid composition of halophytes remains unknown.

185 biosynthesis of membrane lipids and because lipid composition of HIV particles is a major determinan

186 The lipid composition of insulin secretory granules (ISG) ha

187 athogenesis of fat embolism by comparing the lipid composition of lungs positive for fat emboli, and

188 How the distinctive lipid composition of mammalian plasma membranes impacts

189 he argan seed, the anatomy, ploidy level and lipid composition of mature seed tissues were investigat

190 of ELOVL3 leads to selective changes in the lipid composition of meibum, making E3hom mice instrumen

191 nd is presumably triggered by changes in the lipid composition of membrane microdomains.

192 C-MS approach was validated by measuring the lipid composition of microalgae, Chlamydomonas reinhardt

193 o small unilamellar vesicles (SUVs) with the lipid composition of mitochondrial inner membrane and an

194 MS) to image and chemically characterize the lipid composition of oncocytic thyroid tumors, as compar

195 How the distinct lipid composition of organelles is determined and mainta

196 n resonance mass spectrometry to profile the lipid composition of over 30 000 individual rat cerebell

197 The lipid composition of plasma membrane (PM) and the corres

198 with significant alterations in steady-state lipid composition of producer cells and HIV particles.

199 usvirus RdRp activation, we propose that the lipid composition of targeted subcellular membranes migh

200 at the sphingolipids acyl-chain length links lipid composition of TGN subdomains with polar secretory

201 What is the origin and lipid composition of the autophagosome membrane?

202 s of spotted bacteria allowed changes in the lipid composition of the bacteria to be elucidated using

203 atidylglycerol/cardiolipin (CL) to mimic the lipid composition of the bacterial inner membrane, were

204 ion and size of the lipoplex, as well as the lipid composition of the endosomal membrane, have a sign

205 Furthermore, the lipid composition of the inner and outer cotyledons diff

206 hich was previously proposed to modulate the lipid composition of the LCV.

207 Using phase-separated GUVs with known lipid composition of the Ld and Lo phases, we demonstrat

208 at ATR-FTIR captures a global picture of the lipid composition of the liver, along with information f

209 The lipid composition of the meibum isolated from Awat2(-/-)

210 Lipid composition of the membrane and rhodopsin packing

211 ciated membrane proteins and possibly by the lipid composition of the membrane itself.

212 Small changes to the lipid composition of the membrane that do not change the

213 anism with respect to the size of liposomes, lipid composition of the membrane, crowding at the membr

214 urrounding microenvironment, provided by the lipid composition of the membrane, remains to be fully u

215 tioning most likely by providing a favorable lipid composition of the membrane.

216 y peptides/proteins and thereby modulate the lipid composition of the membranes.

217 n sphingomyelin/cholesterol or mimicking the lipid composition of the mitochondrial outer membrane we

218 nce of the methodology to explore changes in lipid composition of the nucleus accumbens from mice sub

219 Analysis of the lipid composition of the outer leaflet is important for

220 transport activity of nhTMEM16 is due to the lipid composition of the reconstitution membranes and to

221 Accordingly, the lipid composition of the stratum corneum of Irf6(-/-) sk

222 bolic processes are strongly modified by the lipid composition of the substrate-carrying membranes, a

223 tion and regulation depends crucially on the lipid composition of the surrounding membrane.

224 The lipid composition of the tunica media reflected the alte

225 Although a role in modulating the lipid composition of the unique mycomembrane has been pr

226 ized the viral membranes, depending on their lipid composition of the viral envelop.

227 ls, may be markedly enhanced by altering the lipid composition of the viral membrane.

228 her eukaryotic microbes may also rely on the lipid composition of their environments as we see increa

229 cale mass spectrometry-based analysis of the lipid composition of three brain regions as well as kidn

230 Here, we studied the lipid composition of thylakoid membranes and chloroplast

231 The lipid composition of thylakoid membranes inside chloropl

232 y nixtamalization and tortilla making in the lipid composition of two corn varieties.

233 Here, we compared the lipid composition of whole cells of the pigmented E. gra

234 Using model membranes mimicking the lipid compositions of eukaryotic organelles, we determin

235 The lipid compositions of GUVs have pronounced effects on in

236 However, the lipid compositions of such domains extracted from the br

237 and time, and in relation to the respective lipid compositions of the MFGM from bovine, goat and she

238 We analyze the lipid compositions of the SV membrane by mass-spectromet

239 However, the influence of lipid composition on caveolae surface stability is not w

240 P cytotoxicity, and therefore the effects of lipid composition on modulating IAPP-membrane interactio

241 nism has the potential to explain effects of lipid composition on the kinetics of any membrane protei

242 distinct decrease in protein and increase in lipid composition on the surface of LPA-treated cells.

243 kcal/mol, revealing a sizeable influence of lipid composition on TM complex stability.

244 metabolism rely on the quantification of the lipid composition or amount.

245 peptide structure as a function of membrane lipid composition or the presence of an anionic lipid en

246 le HA acylation did not influence VLP shape, lipid composition, or HA lateral spacing, acylation sign

247 onstration of pronounced changes in the lens lipid composition over a lifetime, suggests that some li

248 atin was accompanied by selective changes in lipid composition, particularly in the cholesterol conte

249 However, over the long-term at 25 degrees C, lipid composition patterns are not consistent with HVA e

250 activity and is influenced by the membrane's lipid composition, presenting new insights into the spat

251 To assess pathological lung lipid composition, previous knowledge of healthy lung ti

252 which contain additional alterations in leaf-lipid composition relative to fab1.

253 in identification has been determined, their lipid composition remains largely undetermined.

254 at molecular genetic alterations in membrane lipid composition result in many phenotypes, and uncover

255 namics simulations performed using different lipid compositions reveal that the bilayer composition d

256 Analyses of leaf-lipid compositions revealed that mutations at all four o

257 affinity for small unilamellar vesicles with lipid composition similar to synaptic vesicles, in addit

258 of small vesicles (below 300 nm) varying in lipid composition, size and charge; it offers effective

259 ereby the regulation of CNS endothelial cell lipid composition specifically inhibits the caveolae-med

260 nses in growth rate, biomass yield, and core lipid compositions, specifically the degree of core GDGT

261 Mg(2+)-dependent effect is also modulated by lipid composition-specifically by the presence of phosph

262 Lipid composition spectra were acquired from 17 breast t

263 WSVD is therefore the optimal algorithm for lipid composition spectra with highest SNR uniformly acr

264 Droplet size (0.17 versus 1.20 mum), lipid composition (stearin versus olein) and cooling rat

265 al functions of Sac1 include manipulation of lipid composition, sterol enrichment within the VRCs, an

266 Here, we found that changes in lipid composition strongly increased the KcsA open proba

267 gs linking aS scavenging activity with brain lipid composition suggest a possible etiological mechani

268 The influences of solid lipid composition, surfactant blend concentration (2, 4,

269 For most lipid compositions tested, SNARE-mediated and nonspecifi

270 artificial tissues with different formulated lipid composition that contained predefined amounts of o

271 primary cilium require a unique protein and lipid composition that is determined by gating mechanism

272 phospholipids into nanoclusters with defined lipid compositions that determine K-Ras signaling output

273 cisely controlling exposure to vesicles with lipid compositions that mimic both bacterial and mammali

274 phospholipid synthesis and changes membrane lipid compositions that ultimately induce the activation

275 ons, including protein mutations and micelle lipid composition, that lead to increased protein stabil

276 mbrane properties can be manipulated through lipid composition the same way bimodal blends of surfact

277 correlate the viscosity values with membrane lipid composition, the detailed analysis of the correspo

278 Over a broad range of permissive lipid compositions, the Arg-325 variant consistently exh

279 e can be modulated, without major changes in lipid composition, through proteins such as MPP1.

280 he TGN but the underlying mechanisms linking lipid composition to functional polar sorting at TGN sub

281 n supported lipid bilayers (SLBs) of various lipid compositions to characterize the anomalous diffusi

282 s of Drp1 helices on nanotubes with distinct lipid compositions to mimic membrane interactions with t

283 review compares the change of P. tricornutum lipid composition under different treatments, and identi

284 omer and homodimer as a function of membrane lipid composition using a multiscale simulation approach

285 Membrane lipid composition varies greatly within submembrane comp

286 Their lipid composition was quantified.Measurements and Main R

287 of the lipopolysaccharides and the chemical lipid composition was unchanged.

288 g MA to model membranes with well-controlled lipid composition, we dissect the multiple interactions

289 rate the impact of AtLtpI-4 on extracellular lipid composition, we expressed the protein in Arabidops

290 IACYLGLYCEROL ACYLTRANSFERASE (PDAT) on seed lipid composition were assessed in several Camelina sati

291 Three condiment lipid compositions were investigated, 0%, 3.5% and 35%,

292 onstants of one protein interacting with all lipid compositions were simultaneously determined.

293 constituting GltPh into liposomes of defined lipid composition where the primary lipid is phosphatidy

294 ors, but there is no information about their lipid composition, which might reveal candidate theranos

295 es a small amount of energy independently of lipid composition, while direct transition from a stalk

296 is baseline knowledge of healthy lung tissue lipid composition will be extremely useful in future stu

297 reveals a significant change to the cellular lipid composition with drug treatment; furthermore, this

298 twork (TGN) must coordinate specification of lipid composition with selection of secreted proteins.

299 We find that ZIKV significantly alters host lipid composition, with the most striking changes seen w

300 reate enlarged membrane surfaces and optimal lipid composition within the viral replication compartme