1 nt the next generation of oxazolidinones and
lipoglycopeptides.
2 common to all glycopeptides (vancomycin) and
lipoglycopeptides.
3 o a lipopeptide tail, and in the case of the
lipoglycopeptides,
a deoxymannose moiety.
4 ight into the enhanced activity of guanidino
lipoglycopeptides against vancomycin-resistant isolates.
5 Oritavancin is a semisynthetic
lipoglycopeptide analogue of vancomycin that contains th
6 Dalbavancin, a
lipoglycopeptide antibiotic agent that is active against
7 following exposure of the macrophages to the
lipoglycopeptide antibiotic oritavancin.
8 Oritavancin is a
lipoglycopeptide antibiotic that has been shown to be ef
9 Telavancin is a bactericidal
lipoglycopeptide antibiotic that is active against a ran
10 Telavancin is a
lipoglycopeptide antibiotic with potent in vitro activit
11 Oritavancin is a
lipoglycopeptide antibiotic with rapid bactericidal acti
12 ubstantial intracellular accumulation with a
lipoglycopeptide antibiotic.
13 diversification of the glycolipid portion of
lipoglycopeptide antibiotics is simple to perform on a l
14 Dalbavancin is a
lipoglycopeptide antimicrobial agent with a potency sign
15 These findings position guanidino
lipoglycopeptides as candidates for further development
16 , the present discovery of a family of novel
lipoglycopeptides as potent inhibitors of bacterial SPas
17 The core structure of the arylomycins and
lipoglycopeptides consists of a biaryl-linked, N-methyla
18 Telavancin is a semisynthetic
lipoglycopeptide derivative of vancomycin.
19 Mechanistically, guanidino
lipoglycopeptides engaged with bacterial cell wall precu
20 The in vivo efficacy of guanidino
lipoglycopeptide EVG7 was evaluated in a S. aureus murin
21 on of a family of structurally related novel
lipoglycopeptides from a Streptomyces sp. as inhibitors
22 and became the first marketed semisynthetic
lipoglycopeptide in 2009.
23 Long-acting
lipoglycopeptides (
laLGPs), such as dalbavancin and orit
24 Recently, the arylomycins and related
lipoglycopeptide natural products were isolated and show
25 o beta-lactams, aminoglycosides, vancomycin,
lipoglycopeptides,
oxazolidinones, novel tetracycline-de
26 s, including MS and NMR, revealed that these
lipoglycopeptides share a common 14-membered cyclic pept
27 Dalbavancin is a long-acting intravenous
lipoglycopeptide that may be effective for treatment of
28 In contrast to prior work with
lipoglycopeptides,
this study reveals the glucose C3' or
29 etic glycopeptide antibiotics, the guanidino
lipoglycopeptides,
which contain a positively charged gu
30 Oritavancin is a
lipoglycopeptide with bactericidal activity against gram