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1 hibits cholesterol uptake by the low-density lipoprotein receptor.
2 the host-cell receptor, lipolysis-stimulated lipoprotein receptor.
3 for lipoprotein lipase and very-low-density lipoprotein receptor.
4 oproteinase-9 pathway in pericytes through a lipoprotein receptor.
5 ligase IDOL as a negative regulator of brain lipoprotein receptors.
6 regulating neuronal migration by binding to lipoprotein receptors.
7 2 cm(2)+/-0.023 [n=9], P2X7(-/-) low density lipoprotein receptor(-/-) : 0.084 cm(2)+/-0.01 [n=11], P
9 g growth factor beta 1, oxidized low-density lipoprotein receptor 1, and C-C motif chemokine ligand 3
13 NA gemmed from alternative splicing of Lrp6 (lipoprotein receptor 6), a gene highly expressed in vess
18 mice, which are deficient in the low-density lipoprotein receptor and in which hypercholesterolemia i
19 ering, with the discovery of the low-density lipoprotein receptor and its physiology and not only the
20 over, they reveal an unexpected link between lipoprotein receptor and sphingolipid signaling that, in
21 hich promotes the degradation of low-density lipoprotein receptors and, therefore, the increased conc
23 onger Sepp1 isoforms bind to the low density lipoprotein receptor apoER2, but the mechanism remains u
24 DH is caused by mutations in the low-density lipoprotein receptor, apolipoprotein B, or proprotein co
25 tified cholesterol uptake by the low-density lipoprotein receptor as essential for the growth of ALCL
26 Ubiquitous blocking of LRP1 or additional lipoprotein receptors by overexpressing receptor-associa
27 acrophage by modulating oxidized low-density lipoprotein receptor CD36, phagolysosomal maturation blo
29 cassette transporter (atp), and low-density lipoprotein receptor chaperone (ldlr), that are under th
30 that the amino-terminal modular low-density lipoprotein receptor class A (LA) domains within HP14 ar
31 R-Cas9-based screen, we identify low-density lipoprotein receptor class A domain-containing 3 (LDLRAD
32 specific degradation of the LDL (low-density lipoprotein) receptor combined with a 10-week western di
33 -coenzyme A reductase, and human low-density lipoprotein receptor), compared to uninfected controls.
36 oth the Apoe(-/-) and Ldlr(-/-) (low-density lipoprotein receptor deficient) knockout strains, and th
38 cted deletion of DNGR-1 in Ldlr (low-density lipoprotein receptor)-deficient mice (Ldlr(-/-)) signifi
39 a (o/fl)/ LC mice to atherogenic low-density lipoprotein receptor-deficient ( Ldlr(-/-)) mice; and by
41 c lesions from high-fat diet-fed low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice in a tim
42 radiated, atherosclerosis-prone, low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice received
43 t cells in atherosclerosis-prone low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice, we show
51 ecreased hepatic inflammation in low-density lipoprotein receptor-deficient mice on a Western-type di
52 e response pathways in livers of low-density lipoprotein receptor-deficient mice on a Western-type di
55 the AngII-infused hyperlipidemic low-density lipoprotein receptor-deficient mouse (LDLR(-/-)) model,
56 sclerosis-susceptible Ldlr(-/-) (low-density lipoprotein receptor-deficient) mice is substantially hi
60 exin type 9 (PCSK9) binds to the low-density lipoprotein receptor, escorting it to its destruction in
61 onarily conserved pathway for the control of lipoprotein receptor expression and cellular lipid uptak
62 f lower hepatic mRNA editing and low-density lipoprotein receptor expression, and higher levels of ci
64 tein 1 (LRP1) is a member of the low density lipoprotein receptor family and plays important roles in
65 perone that binds LRP1 and other low density lipoprotein receptor family members in the endoplasmic r
66 eptor (VLDLR) is a member of the low-density lipoprotein receptor family that binds multiple ligands
67 tein structurally related to the low-density lipoprotein receptor family that displays a large lumina
68 f-function mutations in the LDL (low-density lipoprotein) receptor gene (LDLR) cause elevated levels
71 aising the expression of SREBP2, low-density lipoprotein receptor, HMGCo-A reductase, and the cholest
75 R/KR) mice are intercrossed with low density lipoprotein receptor knock-out mice (Ldlr(-/-)), they de
78 d PB-NLCs were investigated in a low density lipoprotein receptor knockout (LDLr-/-) mouse model, inc
79 n- (OVA-) sensitized C57BL/6 and low-density lipoprotein receptor knockout mice (LDLr(-/-)) for 5 wee
82 ve transfer of apop(ox)-DCs into low-density lipoprotein receptor knockout mice either before or duri
83 te T cell lipid composition and responses in lipoprotein receptor knockout mice even in the absence o
87 ts an atheroprotective action on low density lipoprotein receptor (LDL-r(-/-)) female mice, but, in c
88 planted into lethally irradiated low density lipoprotein receptor Ldlr(-/-) mice on an atherogenic di
89 bit recognition of oxLDL by KCs, low-density lipoprotein receptor (Ldlr(-/-) ) mice were immunized wi
90 to mice that do not express the low density lipoprotein receptor (Ldlr(-/-)), which are hyperlipidem
91 a Western-type diet and lacking low-density lipoprotein receptor (Ldlr(-/-)T39(-/-)) show decreased
92 oss-of-function mutations in the low-density lipoprotein receptor (LDLR) and homozygous familial hype
94 owth factor-like-A domain of the low density lipoprotein receptor (LDLR) and mediates LDLR degradatio
95 eduction in transcript levels of low-density lipoprotein receptor (LDLR) and of keratin genes known t
96 d glycosaminoglycans (sGAGs) and low-density lipoprotein receptor (LDLR) as host factors contributing
97 lly deficient iPSC utilizing the low-density lipoprotein receptor (LDLR) deficiency Familial Hypercho
99 ficiently blocked PCSK9-mediated low density lipoprotein receptor (LDLR) degradation in cell lines, i
100 n and receptors belonging to the low density lipoprotein receptor (LDLR) family, known to be involved
101 e polymorphism in exon 12 of the low-density lipoprotein receptor (LDLR) gene, rs688, has been associ
102 thionine beta-synthase (CBS) and low-density lipoprotein receptor (LDLr) genes were deficient (Ldlr(-
103 rol and an overexpression of the low-density lipoprotein receptor (LDLR) in pancreatic tumor cells.
107 e recently demonstrated that the low-density lipoprotein receptor (LDLR) is a major apoE receptor in
111 osclerotic lesion macrophages of low-density lipoprotein receptor (Ldlr) knockout mice fed a Western
113 atients who already have reduced low-density lipoprotein receptor (LDLR) levels, such as those with h
117 in type 9 (PCSK9), which reduces low-density lipoprotein receptor (LDLR) recycling and hence choleste
121 ring NAPE-expressing bacteria to low-density lipoprotein receptor (Ldlr)(-/-) mice fed a Western diet
122 te that modulating levels of the low-density lipoprotein receptor (LDLR), a cell surface receptor tha
124 f the identified substrates, the low-density lipoprotein receptor (LDLR), ERdj5 is required not for d
125 N1), Occludin (OCLN), SR-BI, and low-density lipoprotein receptor (LDLR), function mainly at postatta
126 fied 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely p.G116S and p.R730W.
127 eptor molecules CD81, claudin-1, low-density lipoprotein receptor (LDLr), occludin, and SR-BI did not
128 lisin/kexin type 9 (PCSK9) binds low-density lipoprotein receptor (LDLR), preventing its recycling.
129 r the degradation of the hepatic low-density lipoprotein receptor (LDLR), which in turn regulates the
130 of-of-principle, we targeted the low-density lipoprotein receptor (Ldlr), which when deleted, leads t
131 poprotein E (apoE)-deficient and low-density lipoprotein receptor (LDLR)-deficient mice that produce
136 a IDOL and inducible degrader of low-density lipoprotein receptor [LDLR]), with LDL cholesterol stati
137 a mechanism that is dependent on low-density lipoprotein receptors (LDLRs) and LDLR-related protein 1
139 PCSK9 levels, increased hepatic low-density lipoprotein receptor levels, and decreased plasma choles
140 Genetic analysis further revealed that the lipoprotein receptor LRP1 cell-autonomously controls PN
146 s analyzed in aortic arches from low density lipoprotein receptor(-/-) mice consuming a high-choleste
148 lanted into irradiated recipient low-density lipoprotein receptor(-/-) mice, and atherosclerosis was
149 rotein-deficient (apoE(-/-)) and low-density lipoprotein receptor negative (LDLR(-/-)) mice (0.05 mmo
150 DS AND Paradoxically, Ldlr(-/-) (low-density lipoprotein receptor null) mice deficient in miR-146a de
151 ion size was found in Ldlr(-/-) (low-density lipoprotein receptor null) mice transplanted with bone m
152 ed atherosclerosis in irradiated low-density lipoprotein receptor null-recipient mice and in apolipop
154 Cre-IKKbeta-flox system rendered low density lipoprotein receptor-null mice resistant to vascular inf
155 ar smooth muscle lineage of male low-density lipoprotein receptor-null mice, a background susceptible
156 fied alpha2M delivers its misfolded cargo to lipoprotein receptors on macrophages and reduces Abeta1-
157 harboring targeting motifs from low-density lipoprotein receptor or neuron-glia cell-adhesion molecu
158 ermeability, whereas blockade of low-density lipoprotein receptors or exposed lysine residues resulte
159 rest to address drugs and contrast agents to lipoprotein-receptor-overexpressing cancer cells found i
161 arizes our current understanding of the role lipoprotein receptors play in CNS function and AD pathol
163 d dramatic reductions in hepatic low-density lipoprotein receptor protein and increased plasma low-de
164 n/kexin type 9 (PCSK9) regulates low density lipoprotein receptor protein levels by diverting it to l
165 netic ablation of Idol increases low-density lipoprotein receptor protein levels, which facilitates A
167 in the liver can override other low-density lipoprotein receptor regulatory pathways leading to card
168 mation involves Frizzled4 (Fz4), low-density lipoprotein receptor related protein 5/6 (Lrp5/6), Tetra
169 very vehicle which encapsulated carnosine in lipoprotein receptor related protein-1 (LRP-1)-targeted
170 nalization of Abeta bound to the low density lipoprotein receptor related protein-1, a key Abeta clea
171 1/2), to their cognate receptor, low-density-lipoprotein-receptor related protein 6 (LRP6), in the pl
172 distinct receptors, namely, the low-density lipoprotein receptor-related protein (LRP) and cell surf
173 healthy donors was decreased after blocking lipoprotein receptor-related protein (LRP), a CRT recept
174 ously reported that RanBP9 binds low-density lipoprotein receptor-related protein (LRP), amyloid prec
180 We achieve this by targeting the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1) receptor.
181 hat an extracellular fragment of low-density lipoprotein receptor-related protein 1 (LRP-1) was prese
183 MTS-5 is rapidly endocytosed via low density lipoprotein receptor-related protein 1 (LRP1) and degrad
184 ors for these secreted proteins, low-density lipoprotein receptor-related protein 1 (LRP1) and Integr
186 clearance and signaling receptor low density lipoprotein receptor-related protein 1 (LRP1) in both pr
192 lso requires the function of the low-density lipoprotein receptor-related protein 1 (LRP1), a major a
193 associated with its reduction in low-density lipoprotein receptor-related protein 1 (LRP1), an Abeta
194 d both alpha2M and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), in cultur
195 An Abeta clearance receptor, the low-density lipoprotein receptor-related protein 1 (LRP1), is abunda
196 ation of a SNX17 cargo receptor, low-density lipoprotein receptor-related protein 1 (LRP1), led to re
197 apoE and sAbeta compete for the low-density lipoprotein receptor-related protein 1 (LRP1)-dependent
200 ecific interactions of apoE with low-density lipoprotein receptor-related protein 1 on brain vascular
203 s mRNA and protein expression of low density lipoprotein receptor-related protein 2 and alpha-synucle
204 ts with SNMG were retrospectively tested for lipoprotein receptor-related protein 4 (LRP4) antibodies
205 z+ agrin to both heparin and the low-density lipoprotein receptor-related protein 4 (LRP4) coreceptor
208 ain was impaired in mice lacking low-density lipoprotein receptor-related protein 4 (Lrp4), a protein
210 dentified autoantibodies against low-density lipoprotein receptor-related protein 4 (LRP4), an agrin
211 anabolic activity is enhanced by low-density lipoprotein receptor-related protein 4 (Lrp4), which fac
212 euromuscular synapses, and (iii) low-density lipoprotein receptor-related protein 4 (Lrp4), which res
213 ein acting downstream from agrin/low-density lipoprotein receptor-related protein 4 (LRP4)/MuSK, has
214 tified previously in vitro LRP4 (low-density lipoprotein receptor-related protein 4) as a facilitator
215 tein, which interacts with LRP4 (low-density lipoprotein receptor-related protein 4) to activate the
216 dentified novel functions of the low-density lipoprotein receptor-related protein 4-muscle-specific k
217 ditional knockout Wnt coreceptor low-density lipoprotein receptor-related protein 5 (Lrp5) and low-de
218 acid position (p.R1188W) in the low density lipoprotein receptor-related protein 5 (LRP5) gene segre
219 g ligand or receptors, including low-density lipoprotein receptor-related protein 5 (LRP5) gene.
220 yptophan hydroxylase 1 (Tph1) or low-density lipoprotein receptor-related protein 5 (Lrp5) that are i
221 y and show that the co-receptor, low-density lipoprotein receptor-related protein 5 (Lrp5), is requir
222 mice in which a mutation in the low-density lipoprotein receptor-related protein 5 Wnt coreceptor ca
223 , we observed elevated levels of low-density lipoprotein receptor-related protein 5/6 (LRP5/6) and Fr
224 d the Wnt-activated Frizzled and low-density lipoprotein receptor-related protein 5/6 receptors and p
225 it binds to the Wnt co-receptor low-density lipoprotein receptor-related protein 6 (LRP6) in cellula
226 contributions of Wnt coreceptor low-density lipoprotein receptor-related protein 6 (LRP6) in the vas
230 tor-related protein 5 (Lrp5) and low-density lipoprotein receptor-related protein 6 (Lrp6) mice in ad
231 induced by a constitutively active mutant of lipoprotein receptor-related protein 6 (LRP6) or beta-ca
232 n in Xenopus embryos, stimulated low-density lipoprotein receptor-related protein 6 (LRP6) phosphoryl
233 Interactions between Cav-1 and low-density lipoprotein receptor-related protein 6 (LRP6) were repor
234 Additionally, inhibition of low-density lipoprotein receptor-related protein 6 (LRP6) with eithe
235 is gene 2, as well as coreceptor low density lipoprotein receptor-related protein 6 (LRP6), are marke
236 including the expression of the Wnt receptor-lipoprotein receptor-related protein 6 (LRP6), phosphory
241 he E1E2 domain of Wnt coreceptor low-density lipoprotein receptor-related protein 6, Mab2F1, on canon
242 Fetal liver cells derived from low-density-lipoprotein receptor-related protein 6-deficient mice (L
243 uction of frizzleds (fz), arrow (low-density lipoprotein receptor-related protein [LRP] 5/6), disheve
244 e encoding WNT receptors (frizzled [FZD] and lipoprotein receptor-related protein [LRP] family member
245 pse number were mediated via the low-density lipoprotein receptor-related protein and subsequent Ca(2
246 (ADAM9), reticulon 4 (RTN4), and low-density lipoprotein receptor-related protein associated protein
248 tutions within LRP1B, encoding a low-density lipoprotein receptor-related protein tied to both the NM
249 ound that the endocytic receptor low density lipoprotein receptor-related protein-1 (LRP-1) plays a m
253 s including mannose receptor and low-density lipoprotein receptor-related protein-1 (LRP1) have been
254 scular hypothesis, impairment of low-density lipoprotein receptor-related protein-1 (LRP1) in brain c
257 giopep-2 (ANG), a ligand for the low-density lipoprotein receptor-related protein-1 (LRP1), has also
258 -aspartate receptor (NMDA-R) and low-density lipoprotein receptor-related protein-1 (LRP1), which fun
259 vation of beta1 integrin via the low density lipoprotein receptor-related protein-1 (LRP1), which lea
266 exin domain of MMP9 binds to the low-density lipoprotein receptor-related protein-1, triggers phospho
267 some-dependent degradation in an low-density lipoprotein receptor-related protein-1-dependent manner.
269 s and monocytes to MDSCs via the low-density lipoprotein receptor-related protein-2 (LRP2) receptor a
270 nd insulin sensitivity through a low-density lipoprotein receptor-related protein-2 (LRP2)-dependent
271 igand-binding antagonist for the low-density lipoprotein receptor-related proteins (LRPs), and siRNA-
272 a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and
273 hese results complement our understanding of lipoprotein receptor-related proteins 5 and 6 (LRP5/6),
276 how that the soluble form of the low-density lipoprotein receptor relative, LR11/SorLA (sLR11), suppr
277 rotein E receptor 2 and the very low density lipoprotein receptor, resulting in the phosphorylation o
278 itellogenin receptor Yolkless, a low density lipoprotein receptor superfamily member, occur; a functi
279 B type 1), encoded by the gene SCARB1, is a lipoprotein receptor that binds both high-density lipopr
281 BI (SR-BI) and BII (SR-BII) are high-density lipoprotein receptors that recognize various pathogens,
282 th the RELN receptor VLDLR (very low-density lipoprotein receptor); this was confirmed by a RELN-bind
283 odies prevent the degradation of low density lipoprotein receptor, thus lowering serum levels of LDL-
284 venting the recirculation of the low-density lipoprotein receptor to the hepatocyte cell surface.
285 a 95-141) that separates the two low-density lipoprotein receptor type A (LDLR-A) domains does not af
288 a the lipoprotein receptors very low density lipoprotein receptor (VLDLR) and apolipoprotein E recept
289 n E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR) and is internalized by cell
290 d that miR-200c targets the very low density lipoprotein receptor (Vldlr) and its ligand reelin, whic
291 Receptor 2 (ApoER2) and the very low density lipoprotein receptor (VLDLR) are type I transmembrane pr
293 viously, we have shown that very low density lipoprotein receptor (VLDLR) is virtually absent in prea
295 ding through the receptors, Very low-density lipoprotein receptor (Vldlr), Apolipoprotein receptor 2
297 another angiogenic model of very-low-density lipoprotein receptor (Vldlr)-deficient (Vldlr (-/-) ) mi
299 apparent effect of hypoxia on HSPGs, whereas lipoprotein receptors (VLDLR and SR-B1) were transiently
300 an interaction with VLDLR (very low-density lipoprotein receptor), while the APOER2 signaling pathwa