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1 requires the presence of pore-forming toxin listeriolysin O.
2 ecame ill had elevated levels of antibody to listeriolysin O.
3 erum samples were tested for IgG antibody to listeriolysin O.
4 requires the presence of pore-forming toxin listeriolysin O.
5 rotein Ags: hen egg white lysozyme, OVA, and listeriolysin O.
6 s not limited to CD8+ T cells that recognize listeriolysin O.
8 accounted for by a decrease in LM-specific (listeriolysin O(91-99) tetramer(+)) effector CD8(+) T ce
9 aracterize changes in SUMOylation induced by listeriolysin O, a bacterial toxin that impairs the host
12 that pH-sensitive liposomes containing both listeriolysin O and gelonin were more effective than con
13 pression of the phagosome-lysing pore former listeriolysin O and on type I IFN receptor signaling.
14 atural L. monocytogenes-derived soluble Ags (listeriolysin O and p60) revealed that tethering of thes
16 xpression of other critical virulence genes (Listeriolysin O, and two phospholipases plcA and plcB) i
17 l liver kinase-1) to the microbial adjuvant, listeriolysin-O, and used Lm to deliver the Ags and elic
20 ; however, WTLM and L. monocytogenes lacking listeriolysin O (DeltahlyLM) induce similar levels of cy
21 In in vitro experiments, co-encapsulated listeriolysin O enabled liposomal gelonin-mediated B16 c
22 lipid biosynthesis, enhanced the toxicity of listeriolysin O expressed in the host cell cytosol, lead
25 smid containing the invasin gene Inv and the listeriolysin O gene HlyA, which encode two bacterial fa
26 partially dependent on the virulence factor listeriolysin O; however, WTLM and L. monocytogenes lack
27 irement for the essential pore-forming toxin listeriolysin O in mediating escape from phagocytic vacu
28 ncentrations fractions significantly reduced listeriolysin O-induced haemolysis (p < 0.05), and ameli
29 cytoplasmic entry of Listeria facilitated by listeriolysin O is an essential feature not only of the
30 anomer peptides amino acids (aa) 91 to 99 of listeriolysin O (LLO 91-99) and aa 217 to 225 of the p60
31 by the cholesterol-dependent cytolysin (CDC) listeriolysin O (LLO) acts within the infected cell, (ii
32 ast two critical secreted virulence factors: listeriolysin O (LLO) and a broad-specificity phospholip
36 tron microscopy that LM expressing truncated listeriolysin O (LLO) and amino acid fragments 311 to 66
37 on the expression of two secreted proteins: listeriolysin O (LLO) and phosphatidylcholine-preferring
38 virulence factors of Listeria monocytogenes, listeriolysin O (LLO) and phosphatidylinositol-specific
39 to 200 nm, containing the pore-forming toxin listeriolysin O (LLO) and phosphatidylinositol-specific
40 91 to 99 (aa91-99) immunodominant peptide of listeriolysin O (LLO) and to the aa217-225 immunodominan
41 n host cells by using the pore-forming toxin listeriolysin O (LLO) and two phospholipase C enzymes.
42 ) that are deficient in the virulence factor listeriolysin O (LLO) are highly attenuated and are thou
43 the Listeria monocytogenes virulence factor listeriolysin O (LLO) enhances the immunogenicity and an
53 ved cells tested, the pore-forming cytolysin listeriolysin O (LLO) is absolutely required for lysis o
57 ould be attributed partially to insufficient listeriolysin O (LLO) production, indicating a requireme
58 mediated, and a nonamer CTL epitope from the listeriolysin O (LLO) protein has been identified in BAL
60 ytogenes and its secreted pore-forming toxin listeriolysin O (LLO) to identify key signaling events a
61 uction of the hly-encoded secreted hemolysin listeriolysin O (LLO) was also found to significantly en
65 e with an Escherichia coli strain expressing listeriolysin O (LLO), a pore-forming toxin from L. mono
67 the Listeria monocytogenes virulence factor, listeriolysin O (LLO), induces an immune response that c
68 of L. monocytogenes, the pore-forming toxin listeriolysin O (LLO), is sufficient to induce L. monocy
69 ore-forming cholesterol-dependent cytolysin, listeriolysin O (LLO), mediates bacterial escape from ve
70 gen which secretes a pore-forming cytolysin, listeriolysin O (LLO), necessary for intracellular growt
73 e of macrophages from liposomes that contain listeriolysin O (LLO), the hemolytic protein of Listeria
74 ment of mice with a neutralizing mAb against listeriolysin O (LLO), the pore-forming toxin of Listeri
75 r PrfA, including the pore-forming cytolysin listeriolysin O (LLO), two phospholipases C (PlcA and Pl
77 o reduced cytokine production in response to Listeriolysin O (LLO), which activates MC by a TLR2-inde
78 hat secretes a pore-forming cytolysin called listeriolysin O (LLO), which disrupts the phagosomal mem
79 rane is initiated by the secreted haemolysin listeriolysin O (LLO), which is essential for vacuolar e
94 CD8+ T cells specific for the immunodominant listeriolysin O (LLO91-99) epitope provide immunity to L
95 on uninfected cells and may be triggered by listeriolysin O-mediated activation of host response mec
97 -2Kb-restricted CD8 T cells specific for the listeriolysin O molecule mediate significant immunity in
98 cua and a mutant strain of L. monocytogenes (listeriolysin O negative), which do not enter the cytoso
99 provided only pore-forming activity because listeriolysin O of Listeria monocytogenes could substitu
100 ndent cytolysin (CDC) family, which includes listeriolysin O, perfringolysin O, and streptolysin O.
103 single LFn fusion protein containing NP and listeriolysin O protein epitopes in tandem mount a CTL r
104 r30 linked in frame to the L. monocytogenes listeriolysin O signal sequence and driven by the hly pr
105 nocytogenes and induced a subset of effector listeriolysin O-specific CD11a(+) CD8(+) T cells in sple
107 se animals is characterized by activation of listeriolysin O-specific CD8(+) T cells, which are capab
108 with L. monocytogenes dal dat/pRRR generated listeriolysin O-specific effector and memory CD8(+) T ce
109 specific cells were similar to those against listeriolysin O, the immunodominant Ag of L. monocytogen
110 n with WT, heat-killed, or mutant Lm lacking listeriolysin O, the pore-forming hemolysin that promote
111 apsulated inside pH-sensitive liposomes with listeriolysin O, the pore-forming protein that mediates
112 train was constructed in which expression of listeriolysin O was placed under the inducible control o
113 production of the critical virulence factor, listeriolysin O, was compromised by FA modulation, sugge