ライフサイエンスコーパス: listeriosis

1 ogenes (Lm) causes severe foodborne illness (listeriosis).

2 lation-deficient mutant in a murine model of listeriosis.

3 parasite and the causative organism of human listeriosis.

4 athology, and limits bacterial growth during listeriosis.

5 inhibitors (PPIs) may increase the risk for listeriosis.

6 critical role for TRAIL in apoptosis during listeriosis.

7 ng investigations of food-borne outbreaks of listeriosis.

8 e attenuated virulence in the mouse model of listeriosis.

9 40% of sporadic cases and many epidemics of listeriosis.

10 urvival defect in the liver during secondary listeriosis.

11 cs and in a substantial fraction of sporadic listeriosis.

12 lation of leukocyte migration during primary listeriosis.

13 ced IL-1ra and, by inference, IL-1 in murine listeriosis.

14 n in antibacterial resistance during enteric listeriosis.

15 cts of endotoxin but are more susceptible to listeriosis.

16 to improve management and predict outcome in listeriosis.

17 cohort and analyzed the features of neonatal listeriosis.

18 g were required to protect trained mice from listeriosis.

19 PPIs were associated with increased risk of listeriosis.

20 y rate with individuals who develop clinical listeriosis.

21 ial system for early IFN-gamma production in listeriosis.

22 phils (PMN) using a mouse model of foodborne listeriosis.

23 een genetically linked to host resistance to listeriosis.

24 for the life-threatening food-borne disease listeriosis.

25 nes is a Gram-positive bacterium that causes listeriosis.

26 uding cantaloupe, can serve as a vehicle for listeriosis.

27 h produce is a rarely recognized vehicle for listeriosis.

28 cts detailed information about U.S. cases of listeriosis.

29 g were required to protect trained mice from listeriosis.

30 fling, lengthy outbreak of hospital-acquired listeriosis.

31 e degree to which they increased the risk of listeriosis.

32 are able to confer protection against murine listeriosis.

33 mpartment is relevant for protection against listeriosis.

34 e apple may serve as a vehicle for foodborne listeriosis.

35 gnant women and to others at highest risk of listeriosis.

36 gnancy had a 100-1000-fold increased risk of listeriosis.

37 is an intracellular pathogen responsible for listeriosis, a foodborne disease that can lead to life-t

38 lular pathogen Listeria monocytogenes causes listeriosis, a rare but life-threatening disease.

39 psychrotrophic human pathogen that can cause listeriosis, a serious illness for vulnerable population

40 eria monocytogenes is the causative agent of listeriosis, a severe foodborne infection.

41 Pregnancy increases the risk of listeriosis, a systemic disease caused by Listeria monoc

42 and 12 of 189 (6%) who developed late-onset listeriosis; all presented with acute meningitis.

43 ative estimates of the relative risk (RR) of listeriosis among higher-risk populations and a nuanced

44 Foodborne acquisition of listeriosis among hospitalized patients is well document

45 is study quantifies the increases in risk of listeriosis among older persons, pregnant women, and His

46 189 (70%) infants who developed early-onset listeriosis and 12 of 189 (6%) who developed late-onset

47 d isolates from both a 1988 case of sporadic listeriosis and a 2000 listeriosis outbreak, which had b

48 erial growth in this organ may contribute to listeriosis and dissemination of this organism.

49 prevalent clonal group associated with human listeriosis and is strongly associated with cattle and d

50 in TRAIL were partially resistant to primary listeriosis, and blocking TRAIL with a soluble death rec

51 us infections, tuberculosis, histoplasmosis, listeriosis, and malignancy.

52 had a >1000-fold increased risk of acquiring listeriosis, and those with liver cancer; myeoloprolifer

53 erotypes, greater than 90% of human cases of listeriosis are caused by serotypes 1/2a, 1/2b, and 4b a

54 frequently (lineage 3) associated with human listeriosis are sister-groups, and reveal for the first

55 e findings demonstrate the utility of murine listeriosis as a model for dissecting qualitative differ

56 nt and quality of T cell memory using murine listeriosis as a model system.

57 hogen Listeria monocytogenes by using murine listeriosis as a model system.

58 plays a role in host resistance using murine listeriosis as an experimental system.

59 nsas officials were investigating 5 cases of listeriosis at a single hospital when, simultaneously, u

60 igating the pathogenesis of gastrointestinal listeriosis because of its ability to develop systemic i

61 a plays a more limited role during secondary listeriosis, blunting the strength of the delayed-type h

62 nancy-associated and nonpregnancy-associated listeriosis by age and ethnicity.

63 was further characterized in mouse models of listeriosis by determining recovery rates of the wild-ty

64 isability-adjusted life-years (DALYs) due to listeriosis, by synthesising information and knowledge t

65 In the elderly and immunosuppressed, listeriosis can cause septicaemia and central nervous sy

66 Listeriosis can cause severe disease, especially in fetu

67 We searched for listeriosis case series and outbreak investigations publ

68 ates from human (n = 60) and animal (n = 30) listeriosis cases and food samples (n = 30) were randoml

69 More than 98% of reported human listeriosis cases are caused by Listeria monocytogenes s

70 The number of listeriosis cases could be reduced substantially by esta

71 observed significant increases over expected listeriosis cases in their states.

72 ciation between lineage 3 isolates and human listeriosis cases likely reflects rarity of exposure and

73 We identified outbreak-associated listeriosis cases using whole-genome sequencing (WGS), p

74 A total of 762 listeriosis cases were identified during the 6-year repo

75 One hundred sixty-six pregnancy-related listeriosis cases were identified, resulting in a yearly

76 incubation periods among outbreak-associated listeriosis cases, using a simulation model to account f

77 Listeriosis caused by Listeria monocytogenes due to its

78 Listeriosis, caused by Listeria monocytogenes, is an imp

79 c and product trace-back data, detected more listeriosis clusters and solved more outbreaks (2 outbre

80 t not LIGHT(-/-), mice are more resistant to listeriosis compared with wild-type mice, and blockade o

81 nd identified 87 eligible studies containing listeriosis data for inclusion in the meta-analyses.

82 th respect to the pathogenesis and spread of listeriosis depends on the ability of the bacterium to l

83 restrain the bacterial burden during lethal listeriosis despite their reduced fibrin levels.

84 essential for virulence in a murine model of listeriosis due to both respiration-dependent and -indep

85 s the most appropriate small-animal model of listeriosis due to its susceptibility to the same invasi

86 h microbiologically proven maternal-neonatal listeriosis enrolled from November 2009 to December 2017

87 including strains associated with five major listeriosis epidemics.

88 We describe the epidemiology of listeriosis, estimate overall and specific incidence rat

89 e efficiently protected from peritonitis and listeriosis for up to 5 weeks.

90 ulation-based surveillance data for invasive listeriosis from 2004 through 2009.

91 d as patients aged >/=45 years notified with listeriosis from July 1994 to December 2012.

92 their role in the protection against murine listeriosis has not been examined.

93 nd 4b and nearly all outbreaks of food-borne listeriosis have been caused by serotype 4b strains.

94 Outbreaks of food-borne listeriosis have often involved strains of serotype 4b.

95 L23, on L. monocytogenes and orally acquired listeriosis in a gnotobiotic humanized mouse model.

96 We induced systemic listeriosis in CD18 knockout (CD18-ko) and wild-type (WT

97 ortantly, however, susceptibility to primary listeriosis in cytokine-deficient mice does not preclude

98 We examined two features of listeriosis in gravid and nongravid female mice followin

99 an intracellular food-borne pathogen causing listeriosis in humans.

100 mphasizes the high rate of pregnancy-related listeriosis in Israel and shows that specific clones mig

101 Using listeriosis in mice as an experimental model, we found t

102 Listeriosis in mice with the SCID mutation results in a

103 cytogenes that mimics human gastrointestinal listeriosis in mice, we find ILCs to be essential for co

104 prfA in the pathogenesis of gastrointestinal listeriosis in mice.

105 Incidence rates of nonpregnancy-associated listeriosis in patients aged >/= 65 years were 4-5 times

106 a monocytogenes, four outbreaks of epizootic listeriosis in ruminants were investigated through coord

107 al role during the gastrointestinal stage of listeriosis in the guinea pig but is not important for s

108 The clinical manifestations of listeriosis in the pregnant guinea pigs and the tropism

109 limits the bacterial burden during sublethal listeriosis in wild-type mice, FXI-deficient mice displa

110 Overall listeriosis incidence did not change significantly from

111 Among non-pregnancy-associated cases, listeriosis incidence rates increased gradually with age

112 -analysis to impute missing country-specific listeriosis incidence rates.

113 ong non-Hispanic women, pregnancy-associated listeriosis increased from 1.74 to 2.80 cases per 100,00

114 the crude incidence of pregnancy-associated listeriosis increased from 5.09 to 12.37 cases per 100,0

115 osis, maternal-neonatal listeriosis or focal listeriosis) involves clinical observations and microbio

116 Listeriosis is a foodborne disease of significant public

117 Listeriosis is a serious complication in patients underg

118 Listeriosis is a serious food-borne bacterial infection

119 Listeriosis is a serious foodborne infection that dispro

120 Listeriosis is a serious foodborne infection.

121 Listeriosis is a severe foodborne infection and a notifi

122 Although listeriosis is a well-studied infection, a clearer pictu

123 Listeriosis is an infectious disease caused by the bacte

124 at the protective role of Perforin-2 against listeriosis is based on it limiting the intracellular re

125 Listeriosis is caused by the foodborne pathogen Listeria

126 Listeriosis is characterized by bacteremia or meningitis

127 DO is normal, the enhanced expression during Listeriosis is completely abrogated in the absence of IF

128 INTERPRETATION: The severity of listeriosis is higher than reported elsewhere.

129 al antimicrobial therapy when maternal-fetal listeriosis is suspected.

130 a prevalent food-borne pathogen that causes listeriosis, life-threatening disease.

131 In this US outbreak of listeriosis linked to a widely distributed brand of ice

132 The 2014-2015 U.S. nationwide outbreak of listeriosis linked to apples used in commercially produc

133 s with fever, and sporadic cases of invasive listeriosis may be due to unrecognized outbreaks caused

134 eptor-beta agonist, was tested in the murine listeriosis model, the neutropenic rat Pseudomonas aerug

135 in a 100-fold virulence defect in the mouse listeriosis model.

136 pite decades of progress in animal models of listeriosis, much remains unknown about the processes of

137 Outbreaks of listeriosis occur rarely, but have often proved difficul

138 A multistate outbreak of listeriosis occurred in the United States in 1998 with i

139 A) where 6 patients had been admitted before listeriosis onset; these specimens were tested by cultur

140 icaemia, neurolisteriosis, maternal-neonatal listeriosis or focal listeriosis) involves clinical obse

141 Listeriosis or pneumocystosis occurred in 12 of 170 (7%)

142 In June 2014, we detected and investigated a listeriosis outbreak in Denmark using patient interviews

143 We investigated a listeriosis outbreak spanning 7 months and involving 5 h

144 WGS has transformed listeriosis outbreak surveillance and is being implement

145 We investigated a nationwide listeriosis outbreak that occurred in the United States

146 a support the hypothesis that the 2000 human listeriosis outbreak was caused by a L. monocytogenes st

147 1988 case of sporadic listeriosis and a 2000 listeriosis outbreak, which had been linked to contamina

148 Sources of hospital-acquired listeriosis outbreaks can be difficult to identify.

149 Human listeriosis outbreaks in Canada have been predominantly

150 mple, a PFGE type that matched isolates from listeriosis outbreaks in Los Angeles and Switzerland occ

151 was used to analyze isolates from two major listeriosis outbreaks in the United States in 1998 and 2

152 ge I strains are overrepresented in epidemic listeriosis outbreaks, but the mechanisms underlying the

153 s associated with two recent U.S. multistate listeriosis outbreaks.

154 dustry may be the cause of these large-scale listeriosis outbreaks.

155 Relative to WT mice during primary listeriosis, P0 mice exhibited a reduced capacity to cle

156 ctions involving T-cell dysfunction, such as listeriosis, pneumocystosis, mycobacterial infections, a

157 e and acceptable to physicians and patients, listeriosis prevention strategies should be targeted bas

158 Osteoarticular listeriosis primarily involves prosthetic joints and occ

159 s report describes the investigations of two listeriosis pseudo-outbreaks caused by contaminated labo

160 e, the molecular mechanisms of cell death in listeriosis remain to be established.

161 We reviewed cases of listeriosis reported in France from 2001 to 2008.

162 We estimated that, in 2010, listeriosis resulted in 23,150 illnesses (95% credible i

163 years), pregnant women had a markedly higher listeriosis risk (RR, 114.6; 95% CI, 68.9-205.1) than no

164 Listeriosis risk should be considered in fresh produce s

165 Diagnosis of listeriosis (septicaemia, neurolisteriosis, maternal-neo

166 ing L. monocytogenes, the causative agent of listeriosis, serves as a key model for establishing this

167 reatment is associated with reduced neonatal listeriosis severity, justifying the prescription of pre

168 Warfarin treatment exacerbates listeriosis, suggesting that fibrin is the key mediator

169 L/6J mice (AhR(-/-)) are more susceptible to listeriosis than AhR heterozygous (AhR(+/-)) littermates

170 ll mice were significantly more resistant to listeriosis than matched wild-type mice.

171 veloped a competitive index assay for murine listeriosis that tests the virulence of Listeria monocyt

172 We retrieved data on listeriosis through a systematic review of peer-reviewed

173 In a mouse model of listeriosis, uptake of bacteria by the liver at 10 min p

174 ociation in cases of nonpregnancy-associated listeriosis using registry data.

175 r 2004-2009, the overall annual incidence of listeriosis varied from 0.25 to 0.32 cases per 100,000 p

176 R for current use of PPIs and development of listeriosis was 2.81 (95% confidence interval [CI], 2.14

177 The RR of invasive listeriosis was evaluated by age, pregnancy status, and

178 An outbreak of listeriosis was identified in South Africa in 2017.

179 Surveillance for invasive listeriosis was initiated in the states that receive mil

180 The number of DALYs due to listeriosis was lower than those due to congenital toxop

181 re, the resistance of P0L0 mice to secondary listeriosis was significantly reduced in their spleens a

182 The severity of listeriosis we observed in TRPM2(-/-) mice has not been

183 rophages are the principal effector cells in listeriosis, we found that immigrating neutrophils play

184 the causative agent of the foodborne disease listeriosis, we performed a genome comparison of the two

185 c underlying conditions on the occurrence of listeriosis were calculated.

186 and their responses to primary and secondary listeriosis were compared to those of wild-type (WT), Fa

187 From 2001 to 2008, 1959 cases of listeriosis were reported in France (mean annual inciden

188 The mouse model of listeriosis, which was developed in the 1960s, has been

189 trains isolated during epidemic outbreaks of listeriosis, while no human isolates were found in linea

190 In contrast, lethality to listeriosis, whose eradication is dependent upon monocyt

191 Our quantification of the global burden of listeriosis will enable international prioritisation exe

192 InlP is a novel virulence factor for listeriosis with a strong tropism for the placenta.