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1 ormation from complex physical systems where little a priori data is available.
2 nt for the outcomes of such interactions and little about effect sizes.
3                             However, we know little about how changes in winter snowfall will affect
4  altered their brains; however, we know very little about how evolutionary processes (natural or arti
5                            Moreover, we know little about how natural and sexual selection operate on
6                  Specifically, we understand little about how taxonomic and functional diversity cont
7 e governs most biotic processes, yet we know little about how warming affects whole ecosystems.
8                  However, we know relatively little about individual and group responses given the ra
9 s abundance and richness, we know relatively little about nutritional geography-the sources and suppl
10 y in behavior and its motor control, we know little about the evolution of corollary discharges.
11 ply for faculty positions knowing relatively little about the hiring process or what is needed to sec
12                                      We know little about the spatial scales relevant for the outcome
13 d freshwater environments; yet we still know little about their biodiversity.
14 s of information over time; however, we know little about what form this information loss takes.
15 al virus control in chronic infection appear little affected by the absence of major T(M) chemokines.
16                Growth and grain biomass were little affected.
17 ed CUT&Tag libraries can be sequenced for as little as $25 per sample.
18 library generation can be accomplished in as little as 1 week, although 2-3 weeks would be a more typ
19 measure degradation-resistant glycogen in as little as 30 mg of skeletal muscle or a single hippocamp
20 tifying ~10,000 ubiquitylation sites from as little as 500 mug peptide per sample from cells or tissu
21 uantify down to ~10(9) vesicles/mL, using as little as 60 muL of the sample.
22 t chemistry which has received comparatively little attention - defect-induced local distortions and
23 rong assumption, but one that often receives little attention and is used without justification.
24 cerebral blood flow (CBF) relationship, with little attention given to the dynamic relationship betwe
25  inflammatory mediators in TB and AIDS, very little attention has been given to their therapeutic mod
26                                     To date, little attention has been paid to CEF during long-term s
27 There are numerous studies on Li anodes, yet little attention has been paid to the intrinsic electroc
28 ng microbial communities below ground, while little attention has historically been paid to the above
29                   Precipitation has received little attention in glacial erosion studies, but our dat
30 increased in recent years, yet there remains little attention on liposuction, or debulking, as an eff
31 ated outside the head and neck have received little attention until now.
32 plastic additives has received comparatively little attention.
33 rce of the input, this subfield has received little attention.
34 the feathers and blood of geolocator-tracked little auk Alle alle from five Arctic breeding colonies.
35 angers patient outcome, while entrusting too little autonomy results in expertise gaps at the end of
36                                          For little brown bats (Myotis lucifugus), whose populations
37  in care were consistently lower in TW, with little change over time within each group.
38  considered a benign laboratory finding with little clinical importance in the absence of gout or kid
39  well as the state of the art, at comparably little computational cost.
40                            However, there is little consensus about optimal ultrasound parameters req
41 rely by machine learning considerations with little consideration of representing the internalstructu
42  the context of home care, where nurses have little control over the environment and care processes i
43 ith sepsis have improved over the years, but little data are available in patients with trauma who de
44                                     There is little data on how kidney quality, measured by kidney do
45                           However, there are little data on living human microglia, especially in dis
46                            The e-ratio shows little dependence on temperature below 6 degrees C.
47                             LANDD EPSPs show little depression in response to tetanic stimulation and
48 dex for inequality in service coverage makes little difference in some countries, but reduces it by m
49 rements, and most comparative studies showed little difference in the average measures for all the bi
50  of complex behavioural traits, but there is little direct empirical evidence for its occurrence.
51 nduced apoptosis in MESN cells, while having little effect in MYCNA lines.
52      Current childhood asthma therapies have little effect on lung function trajectory.
53 enterovirus (CVB3/28) infectious titer, with little effect on nearly identical mutant strains.
54  five genes, the start site shift likely has little effect on protein synthesis.
55  activity and proteolytic resistance but has little effect on S100A8/S100A9 antimicrobial activity.
56  GR and KL4: however, KLF6, PLZF, and GR had little effect on the bICP0 E promoter.
57                          MCT1 inhibition had little effect on the growth of primary subcutaneous tumo
58 es and are conventionally considered to have little effect on the reaction products.
59 ugh V1 lesioning eliminated V4 theta, it had little effect on V4 gamma power except for delaying its
60 ivergence and adaptive evolution, relatively little effort has focused on how it influences the evolu
61 particular phosphorylation state; surprising little effort on this topic has been expended in computa
62 matic implementation of reactive strategies, little empirical evidence exists as to whether such stra
63                                 Nonetheless, little empirical work has examined the possible independ
64 CI 37.7%-44.7%) despite households obtaining little energy from beverages in that class (17.9 kcal/ho
65                               There has been little evidence linking changes in spiking activity that
66 There is evidence of purifying selection but little evidence of diversifying selection, with substitu
67 tions with brain structure and function with little evidence of regional specificity.
68                                     There is little evidence regarding coordination of opioid managem
69 h early damage with the 24-2 test, there was little evidence that adding the 10-2 test revealed addit
70                                     We found little evidence that sex influenced the probability of a
71                            Although we found little evidence that suramin disrupts glycolytic or glyc
72                             However, we find little evidence that the evolution of hearing and sound
73 t psychosis risk symptoms, however, there is little evidence to suggest that these features emerge in
74  temperature from tree-ring records, we find little evidence to support significant injections of hal
75                                     We found little evidence to support the hypothesis that offspring
76 o known as "electrochemical catalysis", is a little explored approach that has the potential to expan
77  is beginning to emerge as a remarkable, but little explored feature of animal brains.
78                                      In this little-explored habitat, 250 soil cores were sampled fro
79 y a facilitation fusion sensor) generate too little facilitation and too much variance.
80  that the concentrations of TNF-alpha change little from day 3 to day 5-6, but the concentrations of
81 ), acute rather than chronic, or benefitting little from self-care (e.g. dementia) were excluded.
82 rily consumed fatty acids and, unexpectedly, little glucose; secreted glutamine and other nitrogen-ri
83 ir increasing importance, there is currently little guidance on how to design and analyze CRISPR-pool
84 on memory have been studied in many systems, little has been done to test the role of specific clock
85 29 Opp and 19 Dpp sequences that shared very little homology with any other sequence suggesting an ex
86 We suggest that a distinct cold phase in the Little Ice Age around 1450 ce could also have accelerate
87 e to encode stimuli into working memory with little, if any, conscious experience of them.
88 ciated with greater cohort retention but had little impact on incidence or timing of pregnancy detect
89 e symptom cutoff thresholds will likely have little impact on population levels of first-episode psyc
90 tic of "beyond the rule of 5" compounds, has little impact on solubility when log D(7.4) measurements
91 deletion of up to 11 C-terminal residues had little impact on the agonist-induced response.
92 prey ecology, but their significance has had little impact on the conceptual underpinning or practice
93  UM are limited, with clinical trials having little impact.
94 tia but having negative Abeta PET scans show little increase but plasma p-tau181 is increased if CSF
95 cal perturbation of stomatal development has little influence on global two-dimensional stomatal patt
96 pRGCs nearly two decades ago, there is still little information about how or if conventional RGCs (no
97                            However, there is little information about the encounters between white sh
98                          There is relatively little information about TREM2 in DS.
99                                However, very little information is currently available about the abun
100                                     However, little information is known regarding the molecular mech
101                                     There is little information on how nutritional supplementation in
102                            However, there is little information on N(2) O emissions from forest strea
103 tissue damage is assessed qualitatively with little information regarding the underlying pathophysiol
104 to control disease in livestock, but we have little insight into how this impacts antimicrobial resis
105 and LASP2 are highly expressed in the brain, little is currently known about their function in the ne
106                                              Little is known about amisyn, a 24-kDa brain-enriched pr
107 e disorder (AUD) in patients with cirrhosis, little is known about AUD treatment patterns and their i
108                                          Yet little is known about cholinergic influences on motor co
109 red with intra-aortic balloon pumps (IABPs), little is known about clinical outcomes associated with
110 man and Drosophila melanogaster sperm), very little is known about cytoplasmic cilia assembly.
111 US are performed in outpatient settings, yet little is known about facility-level variation in short-
112                                     However, little is known about homeostatic mechanisms in the inta
113                                     However, little is known about how AD risk genes impact synaptic
114  mediating the ability of ungulates to surf, little is known about how drought shapes the green wave
115                                     However, little is known about how edge effects influence the ver
116                                     However, little is known about how excitatory-inhibitory balance
117                                     However, little is known about how HIV-1 latency affects their fu
118                            By contrast, very little is known about how multi-spanning membrane protei
119                        To date, surprisingly little is known about how OR antagonism shapes neuronal
120 quester C for climate change mitigation, yet little is known about how reactive Fe and Al minerals af
121                                              Little is known about how spectral cues contribute to th
122                                     However, little is known about how the ABA-mediated inhibition of
123                       While widely utilized, little is known about how the microenvironment, particul
124 and abnormal dendritic spine morphology, but little is known about how these are related.
125 y and display regional specificity; however, little is known about how these communities differ with
126 ased susceptibility to antibiotics; however, little is known about how these mutations influence bact
127 ors to ecosystem functioning, but relatively little is known about how they respond to extreme storm
128  and DNA-damage-inducible) gene family, very little is known about how this family regulates activity
129  the model species Arabidopsis thaliana, but little is known about how transcriptional dynamics chang
130 al membrane to the extracellular matrix, but little is known about integrin's regulators in the glia.
131                                              Little is known about its evolutionary history.
132 rs resistant to many conventional therapies, little is known about its influence on VDA activity.
133 ies available for SD-associated itch because little is known about its pathophysiological mechanism.
134 4-S) has been studied more extensively, very little is known about mechanisms of regulation or signal
135                                     However, little is known about RAS membrane dynamics and the deta
136                                     However, little is known about stomata in bryophytes, and their e
137 naptic changes after social stress, although little is known about stress-induced inhibitory synaptic
138                                              Little is known about the age-related physiological and
139                                     However, little is known about the association of GlycA with the
140                                     However, little is known about the cellular dynamics that mediate
141                                              Little is known about the changes in symptom classificat
142 L) of children from parental perspective but little is known about the child perception.
143                                     However, little is known about the circuits that integrate these
144                                Additionally, little is known about the configurations of the DNA duri
145                                     However, little is known about the contingencies that lead to the
146 l-penetrating peptides (CPPs); however, very little is known about the design of CPPs for efficient t
147                                     Yet very little is known about the detailed dynamical processes o
148                                     However, little is known about the detailed electrical activity i
149                                              Little is known about the development of aggression regu
150 have been limited to single populations, and little is known about the dynamics of inbreeding depress
151 tcomes following surgery have been examined, little is known about the effect of a patient's communit
152                                     However, little is known about the effect of macromolecular crowd
153                                              Little is known about the effects of eradication of HCV
154                                              Little is known about the effects of the domestication p
155                                     However, little is known about the evolutionary origin of these n
156                                     However, little is known about the exact mode of action of the se
157                                 Importantly, little is known about the factors that cause protein mis
158 corporation events relative to correct), but little is known about the fidelity of NS5B.
159                                          Yet little is known about the functional properties and acti
160 opean ancestry remain understudied, and thus little is known about the genetic architecture of phenot
161  involvement of the animal's microbiome, but little is known about the host's actual role and if it b
162                                              Little is known about the immunopathogenesis of ZIKV-ass
163  the pathogenesis of complex human diseases, little is known about the impact of host genetics on sal
164    Although microbes influence plant growth, little is known about the impact of microbial diversity
165                           However, extremely little is known about the importance of social relations
166                                However, very little is known about the intracellular mechanisms that
167 nsights into the viral infection cycle, very little is known about the location and folding stability
168 ding, rehydration, and pathogen invasion-but little is known about the mechanisms by which this occur
169 xic to most aquatic nontarget organisms, but little is known about the mechanisms causing some specie
170 e assembled into multiprotein complexes, but little is known about the mechanisms required for assemb
171 ntly to chemical fluxes in the deep sea, yet little is known about the microbial communities inhabiti
172  can lead to neuropsychiatric disorders, yet little is known about the molecular basis underlying inh
173                                              Little is known about the molecular make-up of human EEC
174                                              Little is known about the molecular pathology of PNES, m
175 ntaining NPCs during kidney development, but little is known about the molecule(s) regulating FGF sig
176 ation and cognitive and emotional tasks, but little is known about the morphological and molecular di
177                                              Little is known about the mutational landscape of advanc
178                                              Little is known about the natural history of asymptomati
179                                              Little is known about the nature of this individual vari
180 accumbens in motivated performance, but very little is known about the neurochemical underpinnings of
181                                              Little is known about the outcome of patients who experi
182 Blob 2.0 peaked in the summer, a season when little is known about the physical drivers of such event
183                                              Little is known about the population structure of vancom
184 ole in homeostasis, regeneration and cancer, little is known about the post-translational regulation
185 portance for neural circuit function, only a little is known about the postnatal development of dendr
186                                              Little is known about the potential population-level imp
187 an lead to profound changes in behavior, but little is known about the precise molecular mechanisms t
188 lciparum, a unicellular eukaryotic pathogen, little is known about the predominant cytosine modificat
189                                     However, little is known about the processes and factors mediatin
190 key for reproductive success, but relatively little is known about the processes that determine the t
191 tive and negative disease outcomes in TB but little is known about the processes that initiate fibros
192                                     However, little is known about the relationship between hypoxia a
193 diction folklore ("chasing the first high"), little is known about the relevance of cognitive process
194 of stress responses between individuals, but little is known about the relevant synaptic changes asso
195                                     However, little is known about the role of calcineurin in promyel
196 flow and pressure during exercise in health, little is known about the role of ET-1 in the cardiovasc
197                                     However, little is known about the role of exosome-secreted miRNA
198 of dark exposure in adult animals, but still little is known about the role of interneurons and plast
199                                     However, little is known about the role of key elements of the RN
200 er malignancies (e.g. renal cell carcinoma), little is known about the role of this variant in specif
201 nous compounds such as amino acids; however, little is known about the role(s) of nitrogen (N) compou
202                                              Little is known about the roles of myeloid cell subsets
203                                         Yet, little is known about the sources and transport pathways
204                                          Yet little is known about the spatial content of saccade tra
205 l large T antigen (TAg), and malignancy, yet little is known about the specific integration mechanism
206                                     However, little is known about the specificity of extracellular p
207 malian glycosyltransferase family, GT31, but little is known about the structure, substrate recogniti
208 ever, the world major crops are monocots and little is known about the transcriptional programs under
209                                      As yet, little is known about the underlying mechanism.
210 gh MCC has a high propensity for metastasis, little is known about the underlying mechanisms that dri
211 nsiveness to extracellular stimuli, although little is known about the underlying mechanisms that gov
212 nd on the gut microbiota-are chronic(4), and little is known about their BCR repertoires or patterns
213                                     However, little is known about their evolutionary adaptations to
214 their orthosteric agonist peptides, however, little is known about their extracellular domain (ECD) c
215    Despite their epidemiological importance, little is known about their infection phenotypes.
216  a role in periodontitis, although, to date, little is known about their interaction with the vascula
217 s) are enriched in the mammalian brain, very little is known about their potential involvement in bra
218 -1 and DCC is maintained in the adult brain, little is known about their role in mature neurons.
219 tudies revealed their complex social skills, little is known about their social behaviour in the wild
220 tance of interfacial proteins, comparatively little is known about their structure.
221                                     However, little is known about trends in health-care use and heal
222 al fluctuations in brain state, surprisingly little is known about whether and how seizures vary in t
223                                     However, little is known about whether individuals indeed act upo
224                                     However, little is known about whether or how these neural proces
225                                 For example, little is known about which PATs are present in neuronal
226                                     However, little is known as to how comparably large NCs infiltrat
227                                              Little is known however about the natural variability in
228 lex structure called the collar, about which little is known in terms of function and composition.
229  and approaches to managing asthma, of which little is known in this age group.
230                                     However, little is known of direct and indirect fungal interactio
231 ial and cognitive complexity, yet relatively little is known of their social organization in the wild
232                                              Little is known regarding lymph node (LN)-homing of immu
233 erous studies have been performed in adults, little is known regarding the heterogeneity of severe as
234 cyte destruction in NMO is well established, little is known regarding the initial phase of astrocyte
235                                              Little is known regarding the role of CFH in controlling
236                                     However, little is known regarding their precise distribution, in
237                                              Little is known, however, about how our brains accomplis
238                                              Little is known, however, about which interventions have
239                                              Little is known, however, on the temperature sensitivity
240                                              Little is known, however, regarding domains within ZIC p
241                                              Little is understood about dorsal horn circuitry, despit
242  in per capita primary care visit rates, and little is understood about what is contributing to the d
243 ting surgeon workload is poorly studied with little knowledge of the contributing factors impacting w
244                                              Little known, however, is how the morphology of each mus
245  and molecular bases for these functions are little known.
246 ignificantly less phosphorylated glucose and little lactate.
247 reas in eastern Russia the switch occurred a little later (~85 Ma).
248 manders, known from mid-Jurassic rocks, shed little light on the origin of the clade.
249                         Still, there is only little literature on the implementation of radiomics in
250   Recent work has argued that people exhibit little model-based behavior unless it leads to higher re
251 tial time performing exercises that elicited little muscle activation.
252                  However, we still know very little of the genetic mechanisms underlying changes in t
253  of European ancestry and we know relatively little of the genetics of Parkinson's disease in other p
254 orophyll forms within 0.1-20 ps and revealed little or no charge separation and oxidation of the spec
255 he same type of charge as the surface showed little or no difference, except that the signal inverted
256 ti-platelet agents and statins) seem to have little or no effect on CKD-associated MCI, suggesting th
257 generally tailored to act as spectators with little or no function.
258  type of peer review and reviewer gender had little or no impact.
259 plants inventoried at our nurseries provided little or no pollen to honey bees.
260     However, many gene models appear to play little or no role in the traits of an organism.
261 an lithosphere during the Mesozoic, but with little precision on when, or over what time scale.
262                  Despite extensive research, little progress has been made in glioblastoma therapy, o
263                  In addition, there has been little progress in understanding how sleep EEG in differ
264 liferation, but YAP remained cytoplasmic and little proliferation occurred in mouse utricles.
265 ding to the initial haemodynamic status with little regard to the underlying pathophysiological parti
266 End-organ impairment has received relatively little research attention as a possible manifestation of
267 ry patterns and KOA progression has received little research attention.
268 nteractions during mealtime is acknowledged, little research has examined the role of dyadic verbal i
269                                     However, little research has explored how healthcare professional
270  observed actions on the brain response, but little research has explored the effects of manipulation
271 t predictors of various health outcomes, but little research has investigated their influence on fall
272                   Though critical to health, little research has targeted the effect of oil and hypox
273 ures on animal movement have seen relatively little research in avian systems, despite ample evidence
274                                     There is little research on how childhood maltreatment influences
275                      However, there has been little research on the element-level coupling relationsh
276  pharmacoresistant epilepsy, there is rather little research on the neural (re)organization that pote
277                            However, there is little research on the prevalence of practices that migh
278 ventional memory T cell populations, bearing little resemblance to recently activated effectors.
279 ppears to be unique among mammals by showing little scarring or fibrosis after skin or muscle injury,
280  range of functional groups and demonstrates little sensitivity to steric factors on either of the co
281                           HHV-6 demonstrated little specificity to AD brains over controls by either
282 ngi ('evolutionary strata'), which have been little studied and may be more pervasive than commonly t
283  an accumulation of plasmanyl species, a too little studied but biologically important substance clas
284 ue to HFD, and advance understanding of this little-studied gene and its place in the AIF gene family
285           However, attempts at this have had little success to date, suggesting that we need to bette
286  for a 'parity-frailty trade-off', there was little support for our hypothesis that the physiological
287  confidence interval = 0.94-0.97) indicating little time-dependent effect.
288 me temperature-driven yield effects, it does little to change HAR, likely due to infrastructure cost
289 ppreciable tumor localization, often exhibit little to no dissolution and excretion.
290 ated willingness to undergo repeat SRFA with little to no fear in 292 (80.7%) patients.
291 kine, deletion of the X residue (Pro-10) had little to no impact on the folded chemokine structure bu
292 pism for choroid plexus epithelial cells but little to no infection of neurons or glia.
293 ose injected with Cas9 protein (94.2%), with little to no unintended off-target mutations detected.
294 exible enough to detect robust patterns with little to no user supervision can reveal distinctive ins
295  of differentially active TFs, yet find very little transcriptomic changes in steady-state.
296                                     There is little understanding of the participation of each TRPC i
297 yzed by GA-map Dysbiosis test, is subject to little variation over time, and may potentially be used
298                      Cell density shows very little variation within a given cell type.
299                                     However, little was known about how leptin acts in the NTS neuron
300 dismal prognosis, and outcomes have improved little with modern therapeutics.

 
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