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4 altered their brains; however, we know very little about how evolutionary processes (natural or arti
9 s abundance and richness, we know relatively little about nutritional geography-the sources and suppl
11 ply for faculty positions knowing relatively little about the hiring process or what is needed to sec
15 al virus control in chronic infection appear little affected by the absence of major T(M) chemokines.
18 library generation can be accomplished in as little as 1 week, although 2-3 weeks would be a more typ
19 measure degradation-resistant glycogen in as little as 30 mg of skeletal muscle or a single hippocamp
20 tifying ~10,000 ubiquitylation sites from as little as 500 mug peptide per sample from cells or tissu
22 t chemistry which has received comparatively little attention - defect-induced local distortions and
24 cerebral blood flow (CBF) relationship, with little attention given to the dynamic relationship betwe
25 inflammatory mediators in TB and AIDS, very little attention has been given to their therapeutic mod
27 There are numerous studies on Li anodes, yet little attention has been paid to the intrinsic electroc
28 ng microbial communities below ground, while little attention has historically been paid to the above
30 increased in recent years, yet there remains little attention on liposuction, or debulking, as an eff
34 the feathers and blood of geolocator-tracked little auk Alle alle from five Arctic breeding colonies.
35 angers patient outcome, while entrusting too little autonomy results in expertise gaps at the end of
38 considered a benign laboratory finding with little clinical importance in the absence of gout or kid
41 rely by machine learning considerations with little consideration of representing the internalstructu
42 the context of home care, where nurses have little control over the environment and care processes i
43 ith sepsis have improved over the years, but little data are available in patients with trauma who de
48 dex for inequality in service coverage makes little difference in some countries, but reduces it by m
49 rements, and most comparative studies showed little difference in the average measures for all the bi
55 activity and proteolytic resistance but has little effect on S100A8/S100A9 antimicrobial activity.
59 ugh V1 lesioning eliminated V4 theta, it had little effect on V4 gamma power except for delaying its
60 ivergence and adaptive evolution, relatively little effort has focused on how it influences the evolu
61 particular phosphorylation state; surprising little effort on this topic has been expended in computa
62 matic implementation of reactive strategies, little empirical evidence exists as to whether such stra
64 CI 37.7%-44.7%) despite households obtaining little energy from beverages in that class (17.9 kcal/ho
66 There is evidence of purifying selection but little evidence of diversifying selection, with substitu
69 h early damage with the 24-2 test, there was little evidence that adding the 10-2 test revealed addit
73 t psychosis risk symptoms, however, there is little evidence to suggest that these features emerge in
74 temperature from tree-ring records, we find little evidence to support significant injections of hal
76 o known as "electrochemical catalysis", is a little explored approach that has the potential to expan
80 that the concentrations of TNF-alpha change little from day 3 to day 5-6, but the concentrations of
81 ), acute rather than chronic, or benefitting little from self-care (e.g. dementia) were excluded.
82 rily consumed fatty acids and, unexpectedly, little glucose; secreted glutamine and other nitrogen-ri
83 ir increasing importance, there is currently little guidance on how to design and analyze CRISPR-pool
84 on memory have been studied in many systems, little has been done to test the role of specific clock
85 29 Opp and 19 Dpp sequences that shared very little homology with any other sequence suggesting an ex
86 We suggest that a distinct cold phase in the Little Ice Age around 1450 ce could also have accelerate
88 ciated with greater cohort retention but had little impact on incidence or timing of pregnancy detect
89 e symptom cutoff thresholds will likely have little impact on population levels of first-episode psyc
90 tic of "beyond the rule of 5" compounds, has little impact on solubility when log D(7.4) measurements
92 prey ecology, but their significance has had little impact on the conceptual underpinning or practice
94 tia but having negative Abeta PET scans show little increase but plasma p-tau181 is increased if CSF
95 cal perturbation of stomatal development has little influence on global two-dimensional stomatal patt
96 pRGCs nearly two decades ago, there is still little information about how or if conventional RGCs (no
103 tissue damage is assessed qualitatively with little information regarding the underlying pathophysiol
104 to control disease in livestock, but we have little insight into how this impacts antimicrobial resis
105 and LASP2 are highly expressed in the brain, little is currently known about their function in the ne
107 e disorder (AUD) in patients with cirrhosis, little is known about AUD treatment patterns and their i
109 red with intra-aortic balloon pumps (IABPs), little is known about clinical outcomes associated with
111 US are performed in outpatient settings, yet little is known about facility-level variation in short-
114 mediating the ability of ungulates to surf, little is known about how drought shapes the green wave
120 quester C for climate change mitigation, yet little is known about how reactive Fe and Al minerals af
125 y and display regional specificity; however, little is known about how these communities differ with
126 ased susceptibility to antibiotics; however, little is known about how these mutations influence bact
127 ors to ecosystem functioning, but relatively little is known about how they respond to extreme storm
128 and DNA-damage-inducible) gene family, very little is known about how this family regulates activity
129 the model species Arabidopsis thaliana, but little is known about how transcriptional dynamics chang
130 al membrane to the extracellular matrix, but little is known about integrin's regulators in the glia.
132 rs resistant to many conventional therapies, little is known about its influence on VDA activity.
133 ies available for SD-associated itch because little is known about its pathophysiological mechanism.
134 4-S) has been studied more extensively, very little is known about mechanisms of regulation or signal
137 naptic changes after social stress, although little is known about stress-induced inhibitory synaptic
146 l-penetrating peptides (CPPs); however, very little is known about the design of CPPs for efficient t
150 have been limited to single populations, and little is known about the dynamics of inbreeding depress
151 tcomes following surgery have been examined, little is known about the effect of a patient's communit
160 opean ancestry remain understudied, and thus little is known about the genetic architecture of phenot
161 involvement of the animal's microbiome, but little is known about the host's actual role and if it b
163 the pathogenesis of complex human diseases, little is known about the impact of host genetics on sal
164 Although microbes influence plant growth, little is known about the impact of microbial diversity
167 nsights into the viral infection cycle, very little is known about the location and folding stability
168 ding, rehydration, and pathogen invasion-but little is known about the mechanisms by which this occur
169 xic to most aquatic nontarget organisms, but little is known about the mechanisms causing some specie
170 e assembled into multiprotein complexes, but little is known about the mechanisms required for assemb
171 ntly to chemical fluxes in the deep sea, yet little is known about the microbial communities inhabiti
172 can lead to neuropsychiatric disorders, yet little is known about the molecular basis underlying inh
175 ntaining NPCs during kidney development, but little is known about the molecule(s) regulating FGF sig
176 ation and cognitive and emotional tasks, but little is known about the morphological and molecular di
180 accumbens in motivated performance, but very little is known about the neurochemical underpinnings of
182 Blob 2.0 peaked in the summer, a season when little is known about the physical drivers of such event
184 ole in homeostasis, regeneration and cancer, little is known about the post-translational regulation
185 portance for neural circuit function, only a little is known about the postnatal development of dendr
187 an lead to profound changes in behavior, but little is known about the precise molecular mechanisms t
188 lciparum, a unicellular eukaryotic pathogen, little is known about the predominant cytosine modificat
190 key for reproductive success, but relatively little is known about the processes that determine the t
191 tive and negative disease outcomes in TB but little is known about the processes that initiate fibros
193 diction folklore ("chasing the first high"), little is known about the relevance of cognitive process
194 of stress responses between individuals, but little is known about the relevant synaptic changes asso
196 flow and pressure during exercise in health, little is known about the role of ET-1 in the cardiovasc
198 of dark exposure in adult animals, but still little is known about the role of interneurons and plast
200 er malignancies (e.g. renal cell carcinoma), little is known about the role of this variant in specif
201 nous compounds such as amino acids; however, little is known about the role(s) of nitrogen (N) compou
205 l large T antigen (TAg), and malignancy, yet little is known about the specific integration mechanism
207 malian glycosyltransferase family, GT31, but little is known about the structure, substrate recogniti
208 ever, the world major crops are monocots and little is known about the transcriptional programs under
210 gh MCC has a high propensity for metastasis, little is known about the underlying mechanisms that dri
211 nsiveness to extracellular stimuli, although little is known about the underlying mechanisms that gov
212 nd on the gut microbiota-are chronic(4), and little is known about their BCR repertoires or patterns
214 their orthosteric agonist peptides, however, little is known about their extracellular domain (ECD) c
216 a role in periodontitis, although, to date, little is known about their interaction with the vascula
217 s) are enriched in the mammalian brain, very little is known about their potential involvement in bra
218 -1 and DCC is maintained in the adult brain, little is known about their role in mature neurons.
219 tudies revealed their complex social skills, little is known about their social behaviour in the wild
222 al fluctuations in brain state, surprisingly little is known about whether and how seizures vary in t
228 lex structure called the collar, about which little is known in terms of function and composition.
231 ial and cognitive complexity, yet relatively little is known of their social organization in the wild
233 erous studies have been performed in adults, little is known regarding the heterogeneity of severe as
234 cyte destruction in NMO is well established, little is known regarding the initial phase of astrocyte
242 in per capita primary care visit rates, and little is understood about what is contributing to the d
243 ting surgeon workload is poorly studied with little knowledge of the contributing factors impacting w
250 Recent work has argued that people exhibit little model-based behavior unless it leads to higher re
253 of European ancestry and we know relatively little of the genetics of Parkinson's disease in other p
254 orophyll forms within 0.1-20 ps and revealed little or no charge separation and oxidation of the spec
255 he same type of charge as the surface showed little or no difference, except that the signal inverted
256 ti-platelet agents and statins) seem to have little or no effect on CKD-associated MCI, suggesting th
265 ding to the initial haemodynamic status with little regard to the underlying pathophysiological parti
266 End-organ impairment has received relatively little research attention as a possible manifestation of
268 nteractions during mealtime is acknowledged, little research has examined the role of dyadic verbal i
270 observed actions on the brain response, but little research has explored the effects of manipulation
271 t predictors of various health outcomes, but little research has investigated their influence on fall
273 ures on animal movement have seen relatively little research in avian systems, despite ample evidence
276 pharmacoresistant epilepsy, there is rather little research on the neural (re)organization that pote
278 ventional memory T cell populations, bearing little resemblance to recently activated effectors.
279 ppears to be unique among mammals by showing little scarring or fibrosis after skin or muscle injury,
280 range of functional groups and demonstrates little sensitivity to steric factors on either of the co
282 ngi ('evolutionary strata'), which have been little studied and may be more pervasive than commonly t
283 an accumulation of plasmanyl species, a too little studied but biologically important substance clas
284 ue to HFD, and advance understanding of this little-studied gene and its place in the AIF gene family
286 for a 'parity-frailty trade-off', there was little support for our hypothesis that the physiological
288 me temperature-driven yield effects, it does little to change HAR, likely due to infrastructure cost
291 kine, deletion of the X residue (Pro-10) had little to no impact on the folded chemokine structure bu
293 ose injected with Cas9 protein (94.2%), with little to no unintended off-target mutations detected.
294 exible enough to detect robust patterns with little to no user supervision can reveal distinctive ins
297 yzed by GA-map Dysbiosis test, is subject to little variation over time, and may potentially be used