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1 isk loci for late-onset Alzheimer's disease (LOAD).
2 ired with a 2-back working memory task (High-Load).
3 translocation and release, and lowered viral load.
4 or when lifting against a shoulder abduction load.
5 fected fish, irrespective of their pollutant load.
6 x displayed a high alpha-synuclein pathology load.
7 ran ~40% longer, reaching ~51% greater heat load.
8 g in mice increases lesion size and parasite load.
9 for beta-cell adaptation to higher metabolic load.
10 lei deformed nonmonotonically under constant load.
11 ribute to both LOAD risk and age at onset of LOAD.
12 r pressure increases with increasing elastic load.
13 llary load) and may approximate TB bacillary load.
14 rce of both genetic diversity and mutational load.
15 reactivation and correlated with local viral load.
16 r the motor to overcome the viscous cochlear load.
17 fications, and changes to water and sediment loads.
18 solute diaphragmatic work during inspiratory loading.
19 % ee) at an unusually low 0.2 mol % catalyst loading.
20 in vivo joint cartilage exposed to abnormal loading.
21 but it does not rescue the defect in cystine loading.
22 decreasing ocean coverage and increased dust loading.
23 nto supramolecular filaments with a 100% CPT loading.
26 ctin-binding protein profilin to dynamically load actin monomers onto their flexible Formin Homology
30 nal antibodies are predicted to reduce viral load, ameliorate symptoms, and prevent hospitalization.
31 protocols involving step changes in exercise load and compared the results to laboratory-based analys
32 ork, we investigate the relationship between load and contact area spanning the limits of non-adhesiv
34 ge NO(x) emission rate increases with engine load and decreasing ambient temperatures, particularly f
35 ts amplitude and decay rate, lower SR Ca(2+) load and depressed cellular contractility) and SERCA2a d
37 in its activity results in higher bacterial load and exacerbated organ damage, ultimately leading to
40 pheral BACE1 activity is a common feature of LOAD and VAD, thus underlying a further pathogenic link
41 oach, called UVHis-PAGE, that uses metal ion-loaded and fluorescently labeled chelator heads to detec
42 nd by constraining the capacity for future P loading and climate warming to drive cyanobacterial grow
43 beta-cyclodextrin molecular baskets enables loading and delivery of diverse chemicals, and nanoparti
49 ignatures correlate with increased bacterial loads and exacerbate pathology during Mycobacterium tube
50 vity of yeast kinesin-8, Kip3, under varying loads and nucleotide conditions using high-precision opt
52 a levels (>90th percentile) had higher viral loads and were more likely to have respiratory sick visi
54 such as tumor mutation burden and neoantigen load) and the degree of CD8(+) T cell infiltration were
55 aired with a 1-back working memory task (Low-Load), and a third group underwent extinction paired wit
56 cterizing the climate sensitivity of cooling load, and that near-surface humidity plays an equally im
60 a(+)/H(+) exchanger, and regulated glutamate loading as a function of the level of vesicle release.SI
63 ith HIV and not on ART with detectable viral load at baseline were randomly assigned; 666 (51%) were
65 r-adaptor complexes ensures that cargoes are loaded at their origin and unloaded at their destination
67 uence-programmed "zipper lock" by controlled loading, avoiding mutual nonspecific H(1)/H(2) hybridiza
69 on that dynamically balances the computation load between the cores in runtime which guarantees equal
70 OX crystals formed inside LTSLs based on the loading buffer or/and the lipid:DOX ratio used, resultin
71 achieved SVR(12) , 10 had undetectable viral loads but are not eligible for SVR(12) , and 7 remain on
74 es enhance ionic transport under high sulfur loading by forming sufficient triple-phase boundaries be
75 of the trapping and laser parameters during loading can reduce this broadening, enabling state-selec
76 ese nanocarriers allowed for remarkably high loading capacities of hydrophilic antibiotic tobramycin
77 r, current approaches show insufficient drug-loading capacity and inefficient drug release, and requi
79 Functional studies have revealed that iron-loaded carboxymycobactin is imported into the cytoplasm
82 c compounds and ELISA assays showed that the loading-conditioned urine reduced cholesterol and elevat
84 transition from preloading conformers to the loaded conformers in which the loading of Mcm2-7 on DNA
89 gma body may drop well below the lithostatic load, create under-pressure and initiate a caldera colla
92 three to five years into lactation, nematode load did not vary with four different measures of female
93 amidation derivatization of SCFAs with paper-loaded direct analysis in real time mass spectrometry (p
94 for ordering patients along a trajectory of LOAD disease progression from brain transcriptomic data.
95 galcanezumab 120 mg per month (with a 240 mg loading dose administered as two 120 mg injections) for
96 were observed among patients who received a loading dose and those who had a shorter duration of nAM
97 istered intravenously every 3 weeks (8 mg/kg loading dose at first cycle, and 6 mg/kg thereafter) for
98 thereafter) for 18 doses or weekly (4 mg/kg loading dose in the first week, and 2 mg/kg thereafter)
100 estrant 500 mg (day 1) every 28 days (plus a loading dose on day 15 of cycle 1) with either capivaser
101 f 16 mg and 160 mg (with or without a 320 mg loading dose) were associated with significant improveme
102 d to commence subcutaneous dupilumab (600 mg loading dose, then 300 mg once weekly for 15 weeks [n =
104 atalyst performance with high palladium (Pd) loading (e.g., 10 mole %) and a need for (super)stoichio
105 nd 222 nm, encapsulation efficiency (EE) and loading efficiency (LE) values of 67.4 and 63.1%, 26.6 a
110 within 24 hours of detection even when viral load exceeded 1 x 107 HSV DNA copies, and surges in gran
113 bers had significantly higher mean polygenic load for cutaneous melanoma than unrelated cases or mela
114 e interval [CI], 9% to 19%) decline in viral load for each additional year in duration suppressed.
116 he CAD risk associated with a high polygenic load for lipid-increasing variants was proportional to t
118 olygenic score analysis was from the genetic loading for depressive symptoms (p = 0.001, standardized
121 und that the 2019 dissolved reactive P (DRP) load from March-July was 29% lower than predicted, while
127 Weibull regression models for time to viral load >1000 copies/mL (treatment failure), and simulated
129 h a composite poor outcome (defined as viral load >50 copies per mL, or for participants with a missi
132 eptives may increase genital tract HIV viral load (gVL) and sexual transmission risk to male partners
133 lues in the low tertile (i.e. high bacillary load) had 57% 2-week mortality; worse than the intermedi
135 patients with nonhypertrophied, non-pressure-loaded hearts with normal systolic function undergoing c
136 ked rosmarinic liposome (Rososome) which can load high contents of drugs (including 25.8% rosmarinic
140 ased significantly with increasing bacterial load in drinking water in the first year of life (0.79 [
141 ent to reduce the bacterial peripheral blood load in mice following challenge and elicit antibodies t
142 egrase inhibitors rapidly suppress HIV viral load in non-pregnant adults, few published data from ran
143 artners with no report of CD4 count or viral load in the preceding 12 months were presumed not to be
145 V-2 infection is characterized by peak viral load in the upper airway prior to or at the time of symp
146 0 copies per mL) was based on the last viral load in the year preceding elicitation, and viraemia was
148 and new phases, can be induced by mechanical loading in functional materials, providing fundamental i
149 , Cdc6 binds to ORC and the ORC-Cdc6 complex loads in a multistep reaction and, with the help of Cdt1
151 tive responses, did not correlate with viral loads in recipients who became infected, cross-reactivit
153 on and observed that macaques had high viral loads in the upper and lower respiratory tract, humoral
155 eral behavior between uniaxial and torsional loading, in spite of the implicit heterogeneous stress s
158 comparison to SBP, Doppler-derived arterial load indices correlate more strongly with LV hypertrophy
160 cetylases (HDAC4 and HDAC5) are required for loading-induced Sost suppression and bone formation.
162 there was a reduction in cell-associated DNA load, intact proviral DNA levels, and in inducible SIV r
164 levels by decreasing the amount of SNCA mRNA loaded into polysomes, mechanistically providing a cytop
167 s or when the two sites were bound to miRNAs loaded into two different AGO paralogs, AGO1 and AGO2.
168 stability challenges exist when PGM catalyst loading is decreased in a membrane electrode assembly (M
171 mL, or for participants with a missing viral load, lack of retention in care in the on-site ART progr
172 suggest a vulnerability to excess prooxidant loads leading to selective cell death, a therapeutically
173 bral malaria (CM), driven by a high parasite load, leading to parasite sequestration in organs and co
174 d-1 (PSGL-1)-targeted BTZ and ROCK inhibitor-loaded liposomes is more effective than free drugs, non-
176 different treatment options including a top load (low volume) and exchange (large volume) infusion o
177 Of 51 patients with pretreatment viral load <2000 IU/mL, clinical relapse occurred in 10 (19.6
178 IVs, the mean CD4 % was 34%, 93% had a viral load <=20 copies/mL, and 79% were on a nonnucleoside rev
179 MCs that were adjacent to [(13)C]cholesterol-loaded macrophages-including in cytosolic lipid droplets
180 o cartilage explants subjected to increasing load magnitude and in in vivo joint cartilage exposed to
181 -2-specific CD8(+) T cells, applying peptide-loaded major histocompatibility complex class I (pMHCI)
184 nt in CARP9 displayed reduced levels of AGO1-loaded miRNAs, partial retention of miRNA in the nucleus
185 accurate and cost-effective tools for viral load monitoring become crucial to allow specific diagnos
186 es Program performed routine, biannual viral load monitoring on 2489 people living with human immunod
187 rhythms disrupted (ECD) had higher Chlamydia loads, more tissue alterations or lesions, and lower fer
188 drodynamic sizes of HTR-free compared to HTR-loaded nanoMIPs, the HTR binding resulted in a significa
192 in the DTG + FTC arm had an HIV-1 RNA viral load of <50 copies/ml compared to 86/94 (91.5%) particip
193 nuous ART suppression) showed a median viral load of 0.54 cp/ml (interquartile range [IQR], 0.22 to 1
195 n of adolescents who had died or had a viral load of at least 1000 copies per muL after 96 weeks.
197 xcellent shape recovery promoted by a higher load of crosslinker (5 wt%), and superior compressive pr
198 rvival was stronger with increasing relative load of the device and with geolocators attached using e
199 en-9-one was employed as the sensitizer at a loading of 10 mol % in small-scale reactions and of 2.5
200 ecord-high current density per catalyst mass loading of 2000 mA g(cat.) (-1) , as well as good stabil
201 We demonstrate here that, following surface loading of a [Ru(bpy)(3)](2+) (bpy = 2,2'-bipyridine) ch
204 ir molecular weights can be regulated by the loading of Grubbs initiators or by the use of a linear v
205 ormers to the loaded conformers in which the loading of Mcm2-7 on DNA is complete and the DNA entry g
207 inase preferentially suppressed the ribosome loading of mRNAs for functions such as mitochondrial ATP
208 epends on increased expression and chromatin loading of PRIMPOL and is regulated by ATR activity.
209 cation occurs in the phloem and requires the loading of sucrose into the leaf phloem and, at the sink
210 n the 3'-to-5' direction, and facilitate the loading of the helicase DnaB onto the DNA to restart rep
211 otic replication origins are licensed by the loading of the replicative DNA helicase, Mcm2-7, in inac
212 lony loss is due, in part, to the high viral loads of Deformed wing virus (DWV), transmitted by the e
214 unfolding, increasing further the substrate load on proteasomes, and, thus, putting further stress o
215 mperatures, which greatly increase substrate load on the ubiquitin-proteasome system and eventually a
216 yze the combinatorial interaction of ligands loaded on polymeric scaffolds, in both a continuum and d
218 the presence of salt additives, and catalyst loading on ROMP monomer conversion and catalyst lifetime
219 gas desulfurization (FGD)-associated bromide loads on in-stream bromide concentrations in the Mononga
221 ing protein both influences the ways Twinkle loads onto defined DNA substrates and stabilizes the unw
222 acts with the C-terminal part of Ana3, which loads onto the procentriole during interphase, ahead of
228 neous stress state associated with torsional loading, pointed to the ability of the reversible thermo
229 24 blood centers and confirmed as HIV viral load positive or serologically reactive in National Cent
230 more slowly to AIDS and maintain lower viral loads, presumably due to increased breadth of peptide pr
231 the system was used to overcome the Poisson loading problem by sorting for droplets containing a sin
232 nd simultaneous characterization of the drug load profile (i.e., stoichiometric distribution of the n
233 bly and scalability, as well as controllable loading properties, is a flexible platform that can be e
236 nitored at 615 nm, and subsequent Eu(3+)-GTP-loaded RAS interaction with RAF-RBD-Alexa680 monitored a
237 ancer and promoter sequences, whereas Pol II loading rate is primarily modulated by the enhancer.
239 ent was sensitive to crowding - high surface loading reduced conjugates' ability to crosslink recepto
240 a bacterial origin, with increased bacterial loads, reduced diversity and altered composition, which
241 modeling analyses suggest that active cargo loading reduces non-specific encapsulation of cellular p
242 udying the system under different mechanical load regimes and altered dynamics of feedback loops, ill
243 ncentration of concatemer in the IBs, enzyme loading relative to protein concentration, and reaction
249 oops, however, they remain anchored to their loading sites and extrude loops in a 'one-sided' manner.
250 that this likely occurs through the stage of loading soluble N onto the nascent RNA strand as it exit
252 r platelet inhibition by an intensified oral loading strategy (ILS) before PCI impacts on outcomes am
253 onths were presumed not to be in care, viral load suppression (<200 copies per mL) was based on the l
254 (60.9-75.2) to 93.1% (90.2-96.0), and viral load suppression of those on ART increased from 88.7% (8
257 th African guidelines recommend repeat viral load testing within 6 months when human immunodeficiency
258 significantly decreased the number of viral load tests without markedly increasing the number of mon
260 tical fiber presents a 100-1,000x lower heat load than conventional electrical wiring, relaxing the r
268 ions) were eligible for post-pregnancy viral load trajectory analyses (ie, had at least two viral loa
269 l and thus results in significantly enhanced load transfer strengthening and crack-bridging toughenin
270 emorrhagic fever characterized by high viral load, uncontrolled inflammatory response, dysregulated a
271 ted aryl halides and amines at low catalytic loading under metal-free conditions without the need of
273 The distribution of upper respiratory viral loads (VL) in asymptomatic children infected with severe
275 ues, an earlier and sharper decline in viral load was consistently detected for the WT antibody.
276 e and ankle, a model of increasing eccentric load was implemented in the current investigation utiliz
282 c targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of m
284 g with HIV (88% of 1321 with available viral load) were virally suppressed, and 673 HIV-negative men
285 tasks, including a task with minimal memory load-when participants copy an image during viewing.
286 and El Nino, resulting in enhanced nutrient loads which drive HABs in the Indian River Lagoon and La
291 The self-assembly of Tween 80 (T80) micelles loaded with plant-based oregano essential oil (OR) and t
294 ffolds were engineered to bind to hRBP4 when loaded with the orally available small molecule A1120.
296 of UV-sensitive uroporphyrin (URO) and their loading with red light excitable phthalocyanines (PC) th
297 he REGN-COV2 antibody cocktail reduced viral load, with a greater effect in patients whose immune res
300 Tilman demonstrated that increased nutrient loading would also be expected to cause competitive excl