ライフサイエンスコーパス: local administration

1 of disseminated intracavity cancer following local administration.

2 pain, and neuropathic pain via systemic and local administration.

3 ticles decorated with Fc-binding peptide for local administration.

4 ds encapsulating immunomodulatory agents for local administration.

5 of thigh infection through both systemic and local administration.

6 elium (RPE) tissue and skeletal muscle after local administration.

7 s in brain parenchyma away from the point of local administration.

8 f the current delivery strategies, including local administration aiming to avoid systemic toxicities

9 In the future, local administration and sustained, controlled release o

10 ipherally restricted naloxone analog) and by local administration at the inflamed site of monoclonal

11 rticles without a dense PEG corona following local administration by either manual injection or conve

12 d biomaterials have the potential to enhance local administration by improving permeation and retenti

13 Its local administration decreased gingival tissue levels of

14 nt experimental and clinical studies propose local administration directly into the tumor or at the t

15 e in new strategies such as formulations for local administration, e.g., pulmonary administration.

16 from ischaemia-reperfusion injury and, after local administration, enhances nerve regeneration follow

17 cation either by a systemic injection, or by local administration in the form of eye drops.

18 Local administration into perirhinal cortex of the nitri

19 enic amount of S. aureus intravenously or by local administration into the knee joint.

20 Local administration of 2-PMPA in a hypotonic enema vehi

21 A single local administration of 2E' or its combination with pacl

22 lesions and melanoma induced by systemic or local administration of 4-hydroxytamoxifen.

23 ng reduces circadian phase shifts induced by local administration of 8-OH-DPAT (30 microM, i.e., 1.97

24 into the left substantia nigra, followed by local administration of 9 microg of 6-OHDA into the left

25 Local administration of [(11)C]PD153035 greatly increase

26 inhibited (approximately 70%) by systemic or local administration of [D-Trp8]-gamma-MSH.

27 Local administration of a CaMK II inhibitor in the spina

28 low flow dynamics of PAVM, as well as to the local administration of a contrast agent.

29 Here, we show that local administration of a modified vaccinia virus Ankara

30 naling in the IL cortex during extinction by local administration of a neutralizing antibody prevente

31 Local administration of a plant (soybean) lipoxygenase i

32 Here we evaluate the potential for local administration of a small molecule FOLH1/GCPII inh

33 We show that the local administration of AAV8-sgRNA to interscapular BAT

34 Our results suggest that local administration of adenoviral vectors encoding beta

35 Local administration of ADT-007 showed robust antitumor

36 onvection-enhanced delivery (CED) allows for local administration of agents, overcoming the restricti

37 he long-term efficacy and safety of a single local administration of allogeneic expanded adipose-deri

38 Local administration of allogeneic MSCs was not associat

39 ith MetSyn (35 +/- 3 years; P > 0.05) during local administration of alpha-adrenergic agonists (pheny

40 Systemic and local administration of alpha-defensins reduced retinal

41 Local administration of alpha-MSH following injury preve

42 Furthermore, this damage produced by the local administration of ammonia and METH was blocked by

43 expression of B7-1 on the tumor cells or by local administration of anti-CD28 mAb 37N, reinvigorated

44 Our data demonstrate that local administration of apyrase prolonged discordant xen

45 fusion of Foxp3(+) regulatory T cells, or by local administration of aspirin, markedly improved BMMSC

46 e also analyzed for arthritis symptoms after local administration of bacteria.

47 Following a local administration of bafilomycin A1, a V-ATPase inhib

48 at blockade of GABAA receptors in the VPm by local administration of bicuculline greatly increases fo

49 Both intraperitoneal and local administration of bilirubin also was found to amel

50 We evaluated the effects of local administration of bone marrow-derived mesenchymal

51 Local administration of caffeine at the acupuncture poin

52 AR T-cell data from small imaging studies of local administration of CAR T cells in mouse models.

53 ty, exogenous control of CAR expression, and local administration of CAR T cells.

54 hanced an allergic contact response, whereas local administration of cathelicidin before sensitizatio

55 e issues using a combination of systemic and local administration of CB1R antagonists, different meth

56 Systemic and local administration of cholesterol-conjugated antagomiR

57 st, a proinflammatory milieu was elicited by local administration of classically activated M1 MPhis a

58 These results demonstrate that local administration of corticosteroids has no effect on

59 lopment of mucosal tolerance, the effects of local administration of corticosteroids, first-line trea

60 human carboxylesterase gene and concomitant local administration of CPT-11 may have potential as a s

61 The possibility of local administration of CTR1 inhibitors during cisplatin

62 Systemic or local administration of cytokine has been used as a mode

63 To analyze the effects of systemic versus local administration of different types of corticosteroi

64 Local administration of DNA-cationic liposome complex ha

65 are chronic conditions that require repeated local administration of drug, such as noninfectious inte

66 tic tooth movement (OTM) could be blocked by local administration of echistatin or an arginine-glycin

67 Local administration of EGFR inhibitors promotes signifi

68 rabbit model after ischemia produced by the local administration of endothelin-1 to the perineural r

69 ng stenting were randomly assigned to either local administration of enoxaparin during predilation wi

70 istone acetylation, which was restored after local administration of exogenous butyrate.

71 Local administration of exogenous IFN-gamma to the SMG l

72 ting cellular trafficking in the lymph node, local administration of exogenous IP10 into an establish

73 IRPalpha, and FcgammaRs, we demonstrate that local administration of Fc-engineered anti-CD47 antibodi

74 Local administration of FGF9 in Matrigel inhibits hetero

75 (i) Local administration of Go6976 an inhibitor of protein k

76 This data provides the proof of concept that local administration of HB-EGF has the potential to be d

77 Local administration of hcrt1 but not hcrt2 in the LC su

78 Local administration of heme oxygenase-1 adenovirus to s

79 In this study, we tested the effect of local administration of human MSC-Exo on established EAU

80 ital two-photon microscopy, we observed that local administration of IC resulted in dermal DC mobiliz

81 The local administration of ICIs through intratumoral inject

82 In contrast to IGFBP-5, local administration of IGFBP-4 had no significant effec

83 Local administration of IL-1beta sensitizes somatic affe

84 Local administration of IL-6 at the time of infection re

85 tion, such as dissociated response following local administration of immune checkpoint modulators, ps

86 This study supports the finding that local administration of immunotherapeutics, when accompa

87 that systemic, intranasal or intra-accumbens local administration of JWH133, a selective CB(2) recept

88 Local administration of L-arginine after balloon angiopl

89 In the long-term study, local administration of L-arginine enhanced vascular NO

90 al activity within the ischemic territory by local administration of lidocaine.

91 in-immunoreactive cells after stimulation by local administration of ligands.

92 The local administration of LPS/IL4/IL13 into spinal cord le

93 Local administration of MaR1 offers clinical potential t

94 In vivo, local administration of MBV attenuated ultrahigh molecul

95 owed by advancement to systemic medications, local administration of medication and/or surgical proce

96 ent-derived xenograft model to show that the local administration of MEK and Akt inhibitors limits th

97 Furthermore, local administration of methylphenidate in the lateral a

98 These results suggest that local administration of microencapsulated IL-12 can serv

99 Finally, local administration of MIF was able to restore bacteria

100 Furthermore, local administration of minocycline microspheres led to

101 Local administration of nanoparticles with incorporated

102 The local administration of natural or synthetic SIRT activa

103 Local administration of NE provoked an increase in plasm

104 are not directly activated by NGF, although local administration of NGF mediates thermal hyperalgesi

105 -glutamate and PrRP were abolished following local administration of NMDA and non-NMDA-type glutamate

106 Gene targeting by repeated local administration of oligonucleotides may prove clini

107 Finally, local administration of OSU6162 into the nucleus accumbe

108 In addition, a local administration of pDNA miR-200c using CaCO(3) deli

109 of meningeal P2X receptors was achieved via local administration of pharmacological agents.

110 t in vivo programming of adult pericytes via local administration of platelet-derived growth factor B

111 We have previously shown that local administration of polyethylene glycol (PEG, MW: 20

112 aneous stimuli were attenuated or blocked by local administration of receptor antagonists.

113 Local administration of recombinant Fibcd1 (rFibcd1) ame

114 These data show that local administration of rhIL-11 ameliorates early intest

115 Both systemic and local administration of rhNRGbeta1 resulted in a signifi

116 The results showed that local administration of Rp-cAMPS (1 muM), a cAMP antagon

117 Substantial efforts have been made for local administration of small molecules or biologics in

118 Local administration of spermine in vivo protected mice

119 Additionally, we demonstrate that local administration of synthetic NATs accelerates wound

120 laser-Doppler flowmetry over sites following local administration of terazosin (alpha(1)-antagonist),

121 In this study, local administration of TGF-beta3 (200 ng/testis) to the

122 Additionally, local administration of TGF-beta3 to testes in vivo was

123 Local administration of the antibody into the respirator

124 Local administration of the ApN gene significantly reduc

125 was increased eightfold over baseline after local administration of the D2-like (D2, D3, D4) dopamin

126 tracellular dopamine (DA) elicited by either local administration of the depolarizing agent potassium

127 xonal epidermal growth factor receptor, with local administration of the epidermal growth factor rece

128 Local administration of the GABA(A) receptor antagonist

129 so underwent a sentinel node resection after local administration of the hybrid tracer indocyanine gr

130 of this study was to determine the effect of local administration of the interleukin-1 receptor antag

131 In a mouse model of vitiligo, local administration of the JAK1 siRNA significantly red

132 were reversed in a dose-dependent manner by local administration of the muscarinic receptor antagoni

133 P12-deficient lungs, which can be rescued by local administration of the neutrophil chemokine CXCL2.

134 Local administration of the NK1R agonist during skin gen

135 ffects of opiates by examining the effect of local administration of the opiate receptor antagonist m

136 Caspase-1 or -3 deficiency, or local administration of the pan caspase inhibitor, Z-VAD

137 Hyperactivity was remedied by local administration of the pERK inhibitor SL327.

138 In vivo, prolonged local administration of the SCs in mice triggered the in

139 of the skin, an effect that was reversed by local administration of the selective D1 receptor antago

140 Previously, we have shown that systemic and local administration of the selective PDE10A inhibitor T

141 Local administration of therapeutics by inhalation for t

142 GF or stimulate beta1 integrin suggests that local administration of these or similar agents may be e

143 effects may provide therapeutic benefits of local administration of this gene-editing system for HPV

144 In a rat hindlimb VCA model, local administration of this Treg-inducing system, refer

145 immunohistochemical analyses the effects of local administration of TIL on ligature-induced periodon

146 Local administration of TNFalpha to arteries downregulat

147 Local administration of UII into the PPT nucleus increas

148 ureteral relaxation can be improved via the local administration of vasodilators and other smooth mu

149 urs of our established transgenic mice after local administration of viruses encoding Osx, to determi

150 Intracerebroventricular, but not local, administration of UII increases cortical blood fl

151 Local administration or expression of IL-4 in the mouse

152 Local administration-related reactions (mainly mild to m

153 related adverse events were mild or moderate local administration site reactions.

154 ts massive translocation to lymph nodes upon local administration through binding to albumin, affordi

155 Here we report that immune modulation by local administration to the respiratory tract of sphingo

156 After a single local administration with coated balloons, paclitaxel st