ライフサイエンスコーパス: localization

1 tes using graph theory and probability-based localization.

2 adly distributed and less useful for seizure localization.

3 l modification that controls its subcellular localization.

4 show AnkR lacks the domain necessary for AIS localization.

5 ggesting rate enhancement by co-expressional localization.

6 1 activity, while CK2 regulates Tda1 nuclear localization.

7 upted function without affecting subcellular localization.

8 2210 pairs of ion images ranked by their co-localization.

9 ounterparts, facilitating phospho-group site localization.

10 eterogenous depending on tissue and vascular localization.

11 atients, (18)F-JK-PSMA-7 was useful in tumor localization.

12 peptide fragments would not be required for localization.

13 on Dsg1 and desmoplakin for robust cortical localization.

14 Kv1.1), thereby regulating Kv1.1 subcellular localization.

15 calcineurin protein-protein interaction and localization.

16 r-127 modification and promotes YAP1 nuclear localization.

17 ased method for testing claims of functional localization.

18 tween the brainstem nuclei involved in sound localization.

19 , resulting in changes in mRNA stability and localization.

20 e pair sequence resolution or direct spatial localization.

21 efect is not due to defects in actin-related localization.

22 osin-V, are essential for osk mRNA posterior localization.

23 ction methods holds potential to improve BCR localization.

24 a soma-retention signal to achieve dendritic localization.

25 pecificity, ligase activity, and subcellular localization.

26 ace, time, sex, environment, and subcellular localization.

27 for further analysis, including subcellular localization.

28 ein 2 (MKLP2) in targeting to these distinct localizations.

29 t react with self DNA owing to its cytosolic localization(2,12,13); however, recent studies have show

30 yses fully evaluate the feasibility to scale localization across a range of diets.

31 Population genomic and subcellular localization analyses strongly suggest a single-base cha

32 ltiple regions within Set5 that regulate its localization and activity and highlight potential avenue

33 ssociated proteins are also critical for the localization and activity of synaptic neurotransmitter r

34 nd Rgd3 overexpression rescues aberrant Rho3 localization and cell morphologies seen at the restricti

35 pairs channel opening without altering cilia localization and channel assembly.

36 Conclusion The fully automated anatomic localization and classification of fluorine 18-fluorodeo

37 probe represents an attractive tool for the localization and dynamic tracking of functional mitochon

38 ssion of the quantum corrections due to weak localization and electron interactions.

39 ic H3-tail binding causing distinct cellular localization and enhanced H3K9me3-nucleosome ubiquitylat

40 ert an important positive feedback on strain localization and fluid channelization, with potential im

41 apoptosis caused by dysregulation of TDP-43 localization and formation of cytotoxic inclusions.

42 ch modification is important for its dynamic localization and function in the plasma membrane.

43 This SnapShot summarizes the intracellular localization and function of proteins implicated in LSDs

44 We further explored the mechanism of localization and function of two novel desmosome-associa

45 results reveal the role of Vps29 in retromer localization and function, highlighting requirements for

46 ynthetic substrates and to distinguish their localization and functions.

47 division biosynthetic complexes based on its localization and genetic interactions.

48 Both abrogation of BCCIP nucleolar localization and impaired BCCIP-eIF6 interaction can com

49 Docking (D/D) domain, which is essential for localization and interacting with membrane-anchored A-Ki

50 ved in NS5 oligomerization are essential for localization and interaction with components of the cili

51 1 signal-activated PKA increases its nuclear localization and interaction with the nuclear receptor P

52 -scanning mutagenesis of Qtip shows that its localization and interference with cI(VP882) activities

53 cal, super-resolution and EM, we defined DAT localization and its membrane diffusion parameters in me

54 s, and these results showed that mutant CHPK localization and late viral protein expression were seve

55 known modifications, preventing modification localization and limiting the sensitivity of the search.

56 using independent component analyses, source localization and measure projection analyses to compare

57 We describe OCT-guided localization and photocoagulation of these invisible tum

58 d within a parabolic mirror exhibits spatial localization and polarization properties that can be exp

59 A deep learning method for localization and quantification of fluid in all retinal

60 exciting new resource for studying cellular localization and regulation of EGFR in tissues.

61 s, protein essentiality, tissue specificity, localization and solvent accessibility.

62 way from the enzymes, and 3) nucleotidase co-localization and the presence of complementary (positive

63 Spc110 domains that are required for SPB localization and toxicity include its Spc42-, Spc29-, an

64 MB localization and tracking are performed for each sub-pop

65 Localization and tracking of individual receptors are ba

66 oach is generalizable for controlling BODIPY localization and was validated by sensitization of mamma

67 cts beta-cell activity by regulating granule localization and/or priming and calcium signaling in con

68 te the position of PopZ with single-molecule localizations and confirm its position within the riboso

69 ed on the discussion, the mechanisms of nDEP localizations and phase-tuning manipulations are propose

70 Therefore, knowing the localizations and types of receptors and channels presen

71 tudy, we analyze the expression, processing, localization, and cellular functions of human NOCT.

72 hysiological ROS signaling, AMPAR transport, localization, and excitatory transmission.

73 served lncRNAs undergo conserved processing, localization, and function remains unexplored.

74 letal dynamics, controls sensory ion channel localization, and is required to maintain somatosensory

75 t m(6)A could also coordinate the transport, localization, and local translation of key mRNAs in lear

76 regulating co-translational protein folding, localization, and maturation.

77 ells(ARPE-19), their survival, intracellular localization, and the pathological effects, as dysfuncti

78 riments to investigate KOR homodimerization, localization, and trafficking.

79 nstrate that substrate adhesion and integrin localization are enhanced by mammalian fibronectin.

80 e data suggest that functionality and tissue localization are important determinants of CD8+ T cell-m

81 he PVN, TNFR1 expression and plasma membrane localization are upregulated during hypertension induced

82 hrough protein displayed similar subcellular localization as the wild-type progranulin protein.

83 r of targets and their predominant noncoding localization, as well as pervasive pleiotropy and incomp

84 53BP1 to regulate 53BP1 stability and 53BP1 localization at DSBs.

85 eron, both proteins differ in their membrane localization attributes, antibody accessibility, and imm

86 Rare co-localizations between pSTAT5 and vesicular GABA transpor

87 Solvent-driven localization breaks the symmetry and traps the exciton i

88 roximity to Tim-3 and alters its subcellular localization by directing it to Rab 5-positive (Rab 5(+)

89 lation of CMU protein levels and microtubule localization by FRA1 provides a mechanism that stabilize

90 es from PolyFun + SuSiE to perform polygenic localization, constructing minimal sets of common SNPs c

91 ectional white noise, which suppresses sound localization cues but increases overall activity, accele

92 were several proteins that lack subcellular localization data or that are currently assigned to othe

93 Sub-pixel localization demonstrated that during microtubule plus-e

94 by contact to the coverslip but the measured localization densities are in general lower at the basal

95 This behavior suggests that stimulus localization depended on hand assignment, not vice versa

96 n providing chemokines and cytokines for the localization, differentiation, and survival of Trm and T

97 te of 88.5% +/- 0.2 (standard deviation) and localization distances of less than 7 mm.

98 calp and cortical levels using HD-EEG source-localization, during non-rapid eye movement (NREM) sleep

99 Here, we studied the spatiotemporal localization dynamics of the key regulators that master

100 estingly, AtLAC4 had a transient cell corner localization early in fiber development that disappeared

101 elivery efficiency and determine subcellular localization, effects that could permit the targeted del

102 clustering (F1-score 0.96), and molecular co-localization (F1-score 0.90).

103 Its functions require localization first to the chromosome arms and then centr

104 en (14) genes associated with DBSs showed co-localization for both the marks; (iv) only a small fract

105 progenitor cells both had indistinguishable localization from alpha-catulin-GFP+ HSCs.

106 d the expression of Polkappa and shifted its localization from the cytoplasm to the nucleus.

107 e does not change substantially the electron localization function electronic structure of benzene.

108 osolic Ca(2+) contraction signal and spatial localization have all been proposed to encode this hyper

109 e shown to control its cellular and exosomal localization in a cell-specific manner.

110 ical studies revealed hitherto unknown TAAR1 localization in brain areas projecting to the substantia

111 ed F-actin binding in vitro and cytoskeletal localization in cells, demonstrating a common, avidity-b

112 y the most powerful technique for functional localization in cognitive neuroscience, lesion-deficit m

113 red for normal endosomal morphology and IST1 localization in iPSC-derived human neurons.

114 highly conserved protein with submicrovillar localization in midgut cells.

115 time-lapse imaging experiments, VHA(B) -eGFP localization in SDVs precluded accumulation of the acido

116 Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources an

117 on the mobilization of carbon and on strain localization in subducted carbonate rocks.

118 Arabidopsis is reported and tissue-specific localization in the epidermis and mesophyll of isozymes

119 ffer in the number of causal variants, their localization in the genome and their effect sizes.

120 ptors, and immunostaining demonstrated RIMS2 localization in the human retinal outer plexiform layer,

121 absence of Mitf function, cNCC migration and localization in the optic cup are perturbed.

122 ctron heating, we formulate a model for weak-localization in the presence of nonequilibrium transport

123 esponses and the relationship with bacterial localization in the spleens and livers of STm-infected I

124 nd reveal a new molecular mechanism for mRNA localization in vertebrates.

125 cing subpopulations with distinct anatomical localizations in different compartments of murine lungs.

126 lized(14-18) fast radio bursts with four new localizations in host galaxies that have measured redshi

127 No degradation of Pg or localization inside double-membrane autophagosomes was e

128 of other fungal species shows that such dual-localization is also predicted to be common in the ascom

129 t removing Protrudin's endoplasmic reticulum localization, kinesin-binding or phosphoinositide-bindin

130 KARIalpha catalytic activity and subcellular localization, live-cell fluorescence imaging and stimula

131 In the Wireless Localization Matching Problem (WLMP) the challenge is to

132 Collectively, the data suggest that nuclear localization may be important for AtDRO1 function and su

133 However, no comprehensive evaluation of co-localization measures has ever been performed; this lead

134 e, tumor size, grading, proliferative index, localization, mesoappendiceal invasion, lymphovascular i

135 However, cryogenic fluorescence localization methods are, in their majority, diffraction

136 e resolution and accuracy of single-molecule localization microscopes (SMLMs) are routinely benchmark

137 Super-resolution Photo-Activatable Localization Microscopy (PALM) mapping of the static pos

138 ed emission depletion (STED), photoactivated localization microscopy (PALM), stochastic optical recon

139 ed microscopy schemes such as photoactivated localization microscopy (PALM).

140 Implementations such as single-molecule localization microscopy (SMLM) and minimal emission flux

141 Ultrasound localization microscopy (ULM) permits the reconstruction

142 nder large three-dimensional single-molecule localization microscopy datasets.

143 Single-molecule localization microscopy is a powerful tool for visualizi

144 the advancement of live-cell single-molecule localization microscopy is the high excitation power req

145 d conditions for regular and single-molecule localization microscopy on live-cell samples.

146 ing single-molecule images for 3-dimensional localization microscopy or single-molecule tracking.

147 Single-molecule localization microscopy with the new tension probes reso

148 e utilize SMOLM, single-molecule orientation localization microscopy, to directly measure the orienta

149 This differential localization might be related to the emergence of differ

150 emission fluxes (MINFLUX) microscopy in the localization mode exploit fluorophores that blink, i.e.,

151 = 93/388, 24%), biochemical recurrence (BCR) localization (n = 225/388, 58%), or restaging metastatic

152 study, we manipulated three putative nuclear localization (NLS1 to -3) and two potential nuclear expo

153 li ammonia channel (AmtB), provides improved localization of a possible post-translational modificati

154 On-site translation is supported by the localization of a translation initiation factor eIF4E an

155 oadly expressed nuclear protein, and nuclear localization of AFFL-2 is necessary for its role in heat

156 s per cell, (iv) area of aggregates, and (v) localization of aggregates (cytosol, perinuclear, or nuc

157 Here, we first report the cellular localization of alternatively spliced human MOCS1 protei

158 rmation by P. fluorescens occurs through the localization of an adhesin, LapA, to the outer membrane

159 sly demonstrated that EWSR1/FLI1 impairs the localization of Aurora B kinase to the midzone (the midl

160 The new matrix enables DB localization of authentic standards belonging to 12 lipi

161 Co-localization of B- and T-lymphocytes was observed.

162 ro-cancerous Wnt signaling including nuclear localization of beta-catenin and E-cadherin.

163 spectrometry (MS) and tandem-MS (MS(n)), the localization of C=C double bonds (DBs) requires speciali

164 mechanism (two-phase vs solid-solution) and localization of charge give rise to additional kinetic b

165 before significant downregulation of nuclear localization of Cic and demonstrated that their activati

166 his scientific commentary refers to 'Network localization of clinical, cognitive, and neuropsychiatri

167 truncation of 45 amino acids and shifts the localization of ClVST1(97) to plasma membranes in sweet

168 affected the protein levels and microtubule localization of CMU1 and CMU2, thus regulating the later

169 rived neurotrophic factor (BDNF) enhances co-localization of dendritic ZBP1 and PAT1 within granules

170 increased microvascular leakage reverses the localization of directional cues across venular walls, t

171 TRF2-dependent recruitment of MCPH1 promotes localization of DNA damage factors and homology directed

172 Moreover, it turns out that the localization of dyneins in the peripheral supramolecular

173 ity of the EARP complex subunits and for the localization of EARP and its association with membranes,

174 ng seizure dynamics and in defining clinical localization of epileptic pathology.

175 indicates that the R330fs mutant can disrupt localization of ER-alpha and FOXA1.

176 organization and how it controls the spatial localization of filopodial dynamics and thus axon extens

177 ource software suites provide subdiffraction localization of fluorescent molecules, software suites f

178 re we report temperature-dependent photobody localization of fluorescent protein-tagged phyB (phyB-FP

179 CC levels decreased, and cleavage and apical localization of gamma-ENaC increased in nephrotic mice.

180 ange, anatomy and ultrastructure, and tissue localization of Gly decarboxylase subunit P (GLDP) in ni

181 The localization of H2A.Z almost exclusively at the +1 nucle

182 ss of LSH affects the levels and chromosomal localization of H3T3ph and provide evidence that, by mai

183 oll, and Baratte only recently described the localization of HA in the olfactory system of the cuttle

184 Localization of holes on the iodide site in the MHP indu

185 fluorocholine PET/CT imaging in preoperative localization of hyperfunctioning parathyroid glands in a

186 e the microbiome, actively orchestrating the localization of immune cells, to optimize host defence.

187 xt of diabetes, it is unclear what regulates localization of insulin granules and their interactions

188 The localization of Ipl1 to kinetochores in budding yeast de

189 Given the superficial localization of itch neuron terminals, cells that dwell

190 The co-localization of M6PR and of GCC2 with ASOs is influenced

191 RBPs control the translation, stability, or localization of maternal messenger RNAs required for pat

192 Through the quantitative analysis of the localization of MEN components, we determined the relati

193 ation conditions cause increased perinuclear localization of mitochondria and decreased cell prolifer

194 es not affect either piRNA biogenesis or the localization of MIWI2 to the nucleus.

195 oplasmic cilia assembly requires the precise localization of mRNAs encoding key axonemal constituents

196 we investigated the expression and cellular localization of MSI1 and MSI2 in the brains tissues of A

197 w a critical role for mTOR in expression and localization of myelin basic protein (Mbp) mRNA and MBP

198 n of membraneless organelles and subcellular localization of numerous proteins.

199 ence times, we found that the observed Golgi localization of O-glycan-deficient cargos is due to thei

200 targeting and may have a similar role in the localization of other myosin 1s.

201 he current study, we determined the specific localization of Pg in relation to mouse and human pancre

202 current diagnostic strategies do not provide localization of pH alterations.

203 Repressing the expression or nuclear localization of Polkappa might prevent drug resistance i

204 It provides insight into the nature and localization of posttranslational modifications (PTMs) a

205 ns in bacteria function in stabilization and localization of proteinaceous complexes and replicons; h

206 ulatory scaffolding component in mTORC1, and localization of Raptor to the nucleus results in nuclear

207 describe for the first time the subcellular localization of selected Par proteins in blastomeres and

208 We investigated the expression and localization of SEMA4C in primary osteosarcoma patient t

209 on Bub1 kinase activity, and the centromeric localization of SET decreases in a distance-dependent ma

210 Further analysis of the localization of SG cargoes immediately after budding fro

211 We examined the subcellular localization of SlpA secretion and S-layer growth; obser

212 tigated how neuroinflammation relates to the localization of tau and TDP-43 pathology, and to the het

213 th CYLDM719V exhibited increased cytoplasmic localization of TDP-43 and shortened axons.

214 mbly of the telomerase complex, the cellular localization of telomerase and its recruitment to telome

215 actor (TF) binding signal analyses reveal co-localization of TF binding sites based on inferred cis-r

216 hemistry and molecular biology, the cellular localization of the ALC, its effect on carboxysome/cell

217 the DENN domain of SMCR8 drive the lysosomal localization of the complex in conditions of amino acid

218 anoscopy to investigate the submitochondrial localization of the core MICOS subunit Mic60 in relation

219 The CineECG enabled the temporospatial localization of the ECG waveforms, deriving the mean tem

220 Interestingly, the spatial localization of the EGFR to the apical side of the FCs a

221 A prominent example is the preferential localization of the enzyme, glutamine synthetase, in per

222 own, raising questions about the subcellular localization of the final stage of TPP biosynthesis and

223 ftware, conventional recording, and anatomic localization of the ganglionated plexi.

224 duced activation of AMPK and plasma membrane localization of the GLUT4 glucose transporter in skeleta

225 that ICAP1 phosphorylation controls nuclear localization of the ICAP1-KRIT1 complex.

226 Here we report the localization of the melanoma regulatory locus to a singl

227 C), a DNA replication initiator, defines the localization of the origins of replication in eukaryotes

228 aptive responses depending upon identity and localization of the PAMP.

229 of LMNB1 result in a decrease in the nuclear localization of the protein and an increase in misshapen

230 racts with SART3, regulating the subcellular localization of the protein deubiquitinase USP4 and, in

231 uld be accompanied by changes in subcellular localization of the protein products.

232 ChIP-seq-based genome-wide localization of the repressive histone mark H3K27me3 (me

233 e endogenous gene expression and subcellular localization of the sole Na(V) channel in both male and

234 SgmX, in turn, is important for polar localization of the T4P extension ATPase PilB.

235 tructure-targeting compounds to the cellular localization of the target.

236 How cells achieve proper localization of their organelles is still not well-under

237 finity of ASOs for proteins, suggesting that localization of these proteins to LEs is mediated by ASO

238 e IFITM3 at Tyr20, which causes constitutive localization of this protein at the plasma membrane.

239 was assessed by analyzing immunofluorescence localization of TJ proteins, mucosal inulin permeability

240 mbined with Ca(2+) imaging revealed specific localization of TRPV1 to smooth muscle of terminal arter

241 g a heterodimer with AR-FL to induce nuclear localization of unliganded AR-FL, AR-V7 does not need to

242 ne biosynthetic pathway (HBP) allows nuclear localization of YAP1.

243 This localization offers flaw tolerance, allowing ductility t

244 lood circulation times and appreciable tumor localization, often exhibit little to no dissolution and

245 on with membranes, but EIPR1 does not affect localization or function of the related Golgi-associated

246 In the glycinergic sound localization pathway from the medial nucleus of the trap

247 ring this cellular repair, each has a unique localization pattern and knockdown phenotype, demonstrat

248 The T4P localization pattern varies between species; however, th

249 t Cryo-OrbiSIMS reveals the hitherto unknown localization patterns of SVOCs with high spatial and che

250 to round spermatids, and ADAD2 had distinct localization patterns with ADAD2 expressed predominantly

251 oncoproteins, which display unique chromatin localization patterns, often lack classical DNA-binding

252 s in particular showed different markers and localization patterns.

253 short trajectories that feature less than 10 localizations per track.

254 These interactions regulate nuclear localization, phase separation, and stress granule recru

255 Cnb's asymmetric localization, potentially involving a direct relocalizat

256 We illustrate these measures by inferring co-localization properties of 10 273 molecules from 3685 pu

257 rotein turnover is influenced by subcellular localization, protein function, complex association, cel

258 Regardless of the anatomical localization, PSC-BTC exhibited a uniform molecular and

259 Results: In the consensus analysis, BCR localization rates were not higher using advanced recons

260 lution microscopy, light-induced subcellular localization, reaction-diffusion modelling and a spatial

261 This localization requires microtubules and coincides with si

262 sm followed by fast reentry to the nucleus ("localization-resets") activates YAP target genes.

263 The aberrant beta-actin mRNA localization resulted in abnormal dendritic protrusions

264 s combined with patch-clamp and 3D molecular localization reveal that LTP induction thus prompts spat

265 Chromosomal localizations revealed that S. spontaneum MADS-box genes

266 he ring component anillin contains a nuclear localization signal (NLS) that binds to importin and is

267 is coimported into the nucleus with nuclear localization signal (NLS)-bearing paralogues in the NMCP

268 llular studies that HPDL has a mitochondrial localization signal and consequently localizes to mitoch

269 Mutations in the nuclear localization signal in EEEV capsid protein have an addit

270 features include enhancement of the nuclear localization signals in the nucleocapsid protein and dis

271 ssion, BOP1 expression showed expression and localization similar to that in human patient samples.

272 s a major way of controlling the processing, localization, stability, and translatability of mRNAs.

273 has emerged as an important regulator of its localization, structure, aggregation, clearance and toxi

274 olic enzymes matched expectations from prior localization studies, demonstrating the overall reliabil

275 heir interaction, complemented by an in vivo localization study.

276 mpartmentalization through RNA transport and localization, supporting catalytic processes, storage an

277 er's ability to perform signal detection and localization tasks in complex digital images is not unde

278 nts had higher serum LPS and hepatocytes LPS localization than controls, which was correlated with se

279 ifunctional protein with prominent nucleolar localization that shuttles between nucleus and cytoplasm

280 of all three glycoproteins results in their localization to a juxtanuclear region that is presumably

281 on between SHCA and LPP, TGFbeta-induced LPP localization to cellular adhesions depended on SHCA.

282 The functional importance of mRNA localization to centrosomes is unclear.

283 activity or PRC2, thereby facilitating DDB2 localization to cyclobutane pyrimidine dimer crosslinks

284 e anchoring protein (AKAP) 1, modulating its localization to mitochondria and its interaction with pr

285 Localization to P granules is not required for translati

286 We demonstrate that BAIAP2L2 localization to stereocilia tips is dependent on the mot

287 intain mitochondria functional integrity and localization to synapses.SIGNIFICANCE STATEMENT Menkes a

288 p.Glu140* affected FKBP8 localization to the mitochondria and created a truncated

289 entous virus-like particles, suggesting that localization to the plasma membrane, oligomerization int

290 s from both patients showed defective Arl13b localization to the primary cilium.

291 on an interaction with either A33 or A34 for localization to the site of intracellular envelopment an

292 10 is toxic to cells and correlates with its localization to the SPB.

293 By specifically preventing RAB13 RNA localization, we show that peripheral RAB13 translation

294 participation of the C terminus in membrane localization, which is generally overlooked and thus emp

295 -coil CC1 domain is required for microtubule localization, while the C-terminal coiled-coil CC2 domai

296 vels of LRP5/6 and FZD10 and beta-catenin co-localization with enhancer of zeste 2 polycomb repressiv

297 both VGCCs and BK channels, as well as their localization with respect to the presynaptic components

298 his study, we comprehensively quantified HSC localization with up to 4 simultaneous (9 total) BM comp

299 lates cryogenic single-molecule fluorescence localizations with CET reconstructions.

300 preference is not fully predictive of hnRNPK localization within transcripts.