ライフサイエンスコーパス: localized

1 trophin and sarcoglycans, were partially mis-localized.

2 r indicate that all redox couples are ligand-localized.

3 We augment the sample of reported arcsecond-localized(14-18) fast radio bursts with four new localiz

4 The maize chloroplast-localized 6-phosphogluconate dehydrogenase (6PGDH), PGD3

5 s at a high angle to the orogen is spatially localized above the Munger-Saharsa basement ridge.

6 The heat flow is induced by localized absorption of laser light by a cluster of sing

7 opsis (Arabidopsis thaliana), two distinctly localized acetate-activating enzymes, ACETYL-COA SYNTHET

8 synthesis of fatty acids and Leu; peroxisome-localized ACN1 enables the incorporation of acetate into

9 s controlled by Ca(2+)-regulatory mechanisms localized across the membrane in the mitochondrial matri

10 Plastid-localized ACS metabolizes cellular acetate and contribut

11 of actin nucleation to stimulate robust and localized actin filament production in vivo.

12 to sustain, for over six weeks in vivo, the localized activity of the clinically licensed growth fac

13 the critical importance of vIL-6 and its ER-localized activity via gp130 to productive replication i

14 array is presented that allows for wireless, localized actuation through the combined use of light an

15 how that an AT-hook motif-containing nuclear localized (AHL) protein regulates lipid mobilization and

16 bidopsis thaliana, the AT-hook motif nuclear-localized (AHL) transcription factor family has been imp

17 However, the localized air quality improvement was accompanied by a c

18 have been discovered(8), only four have been localized and associated with a host galaxy(9-12), and j

19 o gain insight into the origin of the far-IR localized and delocalized motions present in peptides an

20 les self-aggregate into a depot that remains localized and maintains therapeutic levels of sunitinib

21 e and viscosity measurements revealed highly localized and selective ablation of the bacteria.

22 NSPC grafts organize into localized and spontaneously active synaptic networks.

23 These results support the presence of localized anoxic microsites in the otherwise aerobic por

24 ainly signals in epithelia, thereby inducing localized antiviral immunity.

25 n estimates can quickly become inaccurate in localized areas, particularly where migration or displac

26 ects have effects that are confined to their localized areas, rarely prove fatal for device performan

27 g of uninfected cells shows endogenous Mov10 localized at P-bodies.

28 n was found to be expressed in schizonts, be localized at the apical end of the merozoite, and prefer

29 the core NMD factor UPF1, which is partially localized at the ER in the proximity of the translocon.

30 ological edge modes are excitations that are localized at the materials' edges and yet are characteri

31 The FgPal1 and LifeAct partially co-localized at the subapical region in an interdependent m

32 ution of actomyosin contractility, with pMLC localized at the tips of thin cellular processes in mech

33 which yielded increased mitochondrial matrix-localized ATP via substrate-level phosphorylation.

34 This localized auxin increase balances wound-induced cell exp

35 ebrafish larvae have impaired recruitment to localized bacterial infections and reduced survival that

36 erating different Ti(3+) 3d(1) defect states localized below the Fermi energy.

37 in TLE before surgery that was bilateral and localized beyond the ipsilateral temporal lobe.

38 h the vision of applying these principles to localized, biomaterial-based modulation of tumor-associa

39 can be understood through the elucidation of localized biomolecular networks, or microenvironments.

40 Moreover, functionally localized, body-selective visual cortex responded to fac

41 ubstituted In impurity introduces a striking localized bound state.

42 ood-brain barrier to achieve noninvasive and localized brain drug delivery.

43 Oxygen defects, despite being spatially localized, can profoundly alter global properties such a

44 sive cap dissolves, promoting the autonomous localized cargo release.

45 Here, we study an apicoplast-localized caseinolytic-protease (Clp) system and how it

46 In addition, histologically localized CD3+ T-cells at the tumor center were signific

47 in mice overexpressing nuclear and naturally localized CELF1 protein, with affected genes involved in

48 eir cognate pathogens often triggers a rapid localized cell death at the pathogen infection sites, te

49 These findings establish PAQR4 as Golgi-localized ceramidase required for cellular growth in bre

50 Indeed, recent evidence indicates that localized changes in Ca(2+) in oligodendrocytes can regu

51 obal changes in chromatin structure but only localized changes in DNA methylation, adding another exa

52 With EIT, there are reproducible localized changes in tissue impedance in response to sti

53 ation landscape remained highly stable, with localized changes mainly restricted to CHH methylation.

54 Attempts to identify these localized changes should first account for the restricte

55 Our results implicate localized charge in HA interactions with host cells, and

56 ry of full-length antibodies instead of only localized charges.

57 able: photodynamic therapy, which results in localized chemical damage in the target lesions, and pho

58 duced to generate cartilage for treatment of localized chondral disease in OA.

59 Surgery is the primary therapy for localized chondrosarcoma; for locally advanced and/or me

60 es, such that higher growth rates cause more localized competition.

61 s AP repolarization and consequently induces localized conduction block in tissue.

62 nteric leak from anastomosis, staple line or localized conduit necrosis (9%), and acute delirium (5%)

63 critical regulator of gene silencing through localized control of chromatin compaction, 3D genome org

64 Our data suggest that although localized correction may be achievable using engineered

65 h a mechanically stable substrate upon which localized cortical motor complexes can act on astral mic

66 Immunostaining localized CSF-2 primarily to decidual cell cytoplasm and

67 In situ hybridization data localized DCN expression to areas of microvascular proli

68 roliferation and immunohistochemical studies localized DCN protein expression to the tunica adventiti

69 ntative of the bulk rock, and instead record localized degassing during the final stages of lunar mag

70 of microneedles has facilitated the painless localized delivery of drugs across the skin.

71 Through localized delivery of rapamycin via a biomimetic drug de

72 or can improve cochlear neuron survival, and localized delivery of this protein to the round window m

73 cs in a reversible and conforming system for localized delivery to the sinuses.

74 is a promising technique for noninvasive and localized diagnosis of the molecular profiles of brain d

75 d single-molecule imaging, we show that this localized diffusion slowdown is not due to altered lipid

76 ents who had no lesion visualized on PET/CT, localized disease, and any distant metastases (M1) were

77 section for primary management of high-risk, localized disease.

78 s effective and tolerable when combined with localized DNA-damaging therapies and thus has promising

79 Measurements show control of localized dose deposition and modulation, suitable to ta

80 chromatin compaction changes in response to localized DSBs directly.

81 lobal losses of DNA methylation coupled with localized ectopic gains of DNA methylation that alter tr

82 composition are due to diffusive rather than localized effects on TNF-alpha production.

83 acterization suggests the presence of highly localized electronic states resulting in reasonably fast

84 ctively coupled plasma (LA-ICP)-MSI analysis localized endogenous elements including magnesium and co

85 hate 5-kinase i5 (PIPKIgammai5), an endosome-localized enzyme that produces phosphatidylinositol 4,5-

86 or quantification and analysis of ctDNA from localized esophageal tumors.

87 void nanometer-sized bubble forms around the localized excitation (He[Formula: see text]) within 1 ps

88 Universe using the dispersion of a sample of localized fast radio bursts; this technique determines t

89 om patients with Dupuytren's disease (DD), a localized fibrotic disorder of the palm, we sought to id

90 rgeting FMN2, we show that spindle-periphery localized FMN2 is required for spindle migration.

91 al nationwide closed system that prioritizes localized food.

92 Localized forest impacts associated with the wood pellet

93 h vesicular carriers that recruit GGA (Golgi-localized, gamma-ear-containing, ARF-binding protein), c

94 e of these signatures involve genomically co-localized genes resulting from the presence of copy numb

95 ddW), which we have identified as a divisome-localized glycosyl hydrolase that cleaves peptide-free P

96 aging and iontophoresis of acetylcholine and localized heating.

97 sting of recombinant proteins from a surface-localized heme transport system containing near-iron tra

98 R by tightly sequestering HdrR in a membrane-localized heteromeric HdrR/M complex.

99 Localized high concentrations have been observed in the

100 Recently localized high-concentration electrolytes (LHCEs) are em

101 ytes such as superconcentrated electrolytes, localized high-concentration electrolytes, and highly fl

102 Patients had localized high-risk STS (grade 3; size, >= 5 cm) of an e

103 uvant CHT and RP in patients with clinically localized, high-risk PC at this time.

104 Men with clinically localized, high-risk PC were assigned to RP alone or neo

105 ten inadequate in curing men with clinically localized, high-risk prostate cancer (PC).

106 This AMPK activation triggers localized hillock autophagosome accumulation and mitopha

107 set-up capable of achieving simultaneous co-localized imaging of spatially correlated far-field supe

108 n of PVPON/TA-encapsulated islets can elicit localized immunosuppression and potentially delay graft

109 and ZmMC2, but not ZmMC9, are predominantly localized in a punctate distribution in both N. benthami

110 ptual frameworks for how these molecules are localized in cells and tissues.

111 s, IFITM3 was minimally expressed and mainly localized in endosomes.

112 te, and a specific interaction motif that is localized in intracellular loop 3.

113 s limb assignment: the crossed right hand is localized in left space, and this conflict presumably pr

114 We show that GFP-tagged proteins can be localized in nanaerobically growing bacteria.

115 pollination-induced ovule development and is localized in ovule primordia.

116 r acute lung injury, they are preferentially localized in regenerating regions of the alveolus.

117 calization revealed that this transcript was localized in the cytosol, prompting us to evaluate its c

118 consecutive patients with esophageal cancer localized in the distal esophagus or gastroesophageal ju

119 ed to perform in trans catalysis, i.e. while localized in the ER, Opi3 would methylate lipid substrat

120 , we showed that PROX1 is expressed in sNCCs localized in the NoR and in the pelvic plexus.

121 naked mole-rat p53 protein is constitutively localized in the nucleus prior to DNA damage.

122 y an oscillator whose various components are localized in the nucleus, centrosome, and cytoplasm.

123 iii) In uninfected HEp-2 cells, hnRNPA2B1 is localized in the nucleus.

124 All enzymes were localized in the plant Golgi apparatus, which allowed us

125 Our data suggest that EVE is localized in the plasma membrane and is involved in pota

126 a, while in adults, the crystals were mostly localized in the posterior corneal stroma with the depth

127 The CRC protein triadin (T95) is localized in the sarcoplasmic reticulum (SR) subdomain o

128 lity that ovulation may be responsible for a localized inflammatory response.

129 cted organ or animal is needed to understand localized inflammatory responses that results during hos

130 ([Ca(2+)](i)) by endoplasmic reticulum (ER)-localized inositol 1,4,5-trisphosphate receptor (InsP(3)

131 The probe signal localized intracellularly and at the cell wall-membrane

132 Our study reveals that nuclear-localized IPMK acts as a chaperone to inhibit LLPS of TF

133 Localized iron accumulation and callose deposition in th

134 systole, stimuli were detected and correctly localized less frequently, relating to a shift in percep

135 summary, OsPHT2;1 functions as a chloroplast-localized low-affinity Pi transporter that mediates UV t

136 In unstimulated ECs, YAP localized mainly in the cytoplasm.

137 ty of soil salinity/sodicity are extensively localized, making predictions on a global scale difficul

138 n in lung CYP2A levels, which may impact the localized metabolism of inhaled drugs and tobacco smoke

139 -cyano-4'-pentylbiphenyl) triggers spatially localized (micrometer-scale) and transient (subsecond) f

140 mic Ca(2+) regulation of intermembrane space-localized MICU1/2 is controlled by Ca(2+)-regulatory mec

141 Such localized models must also be developed even when the da

142 We functionally localized modifiers of cAMP signaling, the photo-activat

143 , combined with second-generation absolutely localized molecular orbital energy decomposition analysi

144 ever, recent studies have shown that cGAS is localized mostly in the nucleus and has low activity as

145 band (RB) in spirotrich ciliates, which is a localized, motile hub that traverses the macronucleus wh

146 active closed-shell singlet species with one localized N=P and one C=P double bond, whereas the heter

147 as predominantly expressed in mast cells and localized near 15-LO(+) epithelium in NPs from patients

148 echanism into hot electrons that are instead localized near a 2D van Hove singularity explains the an

149 ization of Na(V)1.5 away from dense clusters localized near GJs and MJs to a more diffuse distributio

150 t are either linked with GPCR trafficking or localized on endosomes, we identified signal-transducing

151 PLP-1 orthologs localized on RNA granules may similarly contribute to ge

152 s excited at 740 nm, the excitation remained localized on the long-wavelength chlorophyll forms withi

153 It normally causes localized or disseminated systemic diseases, particularl

154 Methods: We studied 5 patients with localized or metastatic ccRCC in a microdosing regimen,

155 noscale devices, because the field cannot be localized or screened.

156 Although electron transfer involves metal-localized orbitals, investigations of [(P(6)ArC)Fe(2)(mu

157 We show that localized oxygen depletion results in hydrogen productio

158 We identified localized patterns of gray matter density (GMD) changes

159 ansitions-from normal prostate epithelium to localized PCa to metastases-in specimens derived from hu

160 In localized PCa, stringent expression filtering identified

161 The severity of localized periodontitis was defined as healthy (n = 42),

162 MRI with (160)Gd-labeled antibodies revealed localized peritumoral ring enhancement, which correspond

163 Electrolysis of saline creates localized pH gradients that drive adipocyte death and sa

164 satellites along with climate data estimated localized phenological parameters.

165 Confocal microscopy specifically localized PHIP to the force transduction layer, together

166 Immunofluorescence analysis localized PHIP to the leading edge of glioblastoma cells

167 signature arises from defect-induced pseudo-localized phonon modes-that is, resonant states resultin

168 during gametogenesis and are required for ER-localized phospholipid metabolism in vegetative and repr

169 carotenoid, lycopene, is sensitive to fruit-localized PHY-dependent temperature perception.

170 ween brain regions and identify a regionally localized pial subpopulation marked by the expression of

171 We find that localized PKA activity in migrating cells rapidly decrea

172 This method exploits the fact that the localized plasmon resonance (LSPR) of the plasmonic nano

173 te a simple approach to control and switch a localized polariton vortex between opposite states.

174 Polkappa increased the abundance of nuclear-localized Polkappa, particularly in response to the BRAF

175 GALNT2 encodes the Golgi-localized polypeptide N-acetyl-d-galactosamine-transfera

176 ve been reported for directly confirming the localized presence of the template.

177 (ADT) is a standard definitive treatment of localized prostate cancer (LPCa).

178 conducted a systematic literature review of localized prostate cancer biomarker studies between Janu

179 We deployed the system specifically for localized prostate cancer by integrating large-scale pro

180 In men with localized prostate cancer, the addition of androgen-depr

181 t a variety of solid human tumors, including localized prostate cancer.

182 nstructing the evolutionary histories of 293 localized prostate cancers from single samples, and eigh

183 e nuclear gene can be translated into a dual localized protein that distributes between the cytosol a

184 suggests AtDRO1 is predominantly a membrane-localized protein.

185 ous Cryptococcus mRNAs encode predicted dual-localized proteins, including many aminoacyl-tRNA synthe

186 ere the ATP synthase can readily utilize the localized proton density to drive ATP synthesis.

187 enhances the transmembrane-electrostatically localized proton density to the crista tip where the ATP

188 acitance for transmembrane-electrostatically localized proton energy storage; and 2) The geometric ef

189 nction while providing improved diagnosis of localized pulmonary diseases.

190 agonal deterministic disorders for realizing localized quantum walks deterministically.

191 time the demonstration of quantum walks and localized quantum walks in a new type of optical fibers

192 logy was used to estimate the area under the localized receiver-operating-characteristic curve (ALROC

193 om prey ants, which triggered both increased localized recruitment and slowed advancement of the raid

194 h a massively parallel mutagenesis assay, we localized regulatory activity to a central core region t

195 of DPSMA as a potential tool for evaluating localized renal masses.

196 dy demonstrated DPSMA uptake and kinetics in localized renal masses.

197 rchlight are biased by design toward finding localized representations.

198 ermined, a mutant deficient in the thylakoid-localized respiratory terminal oxidases and CytM (DeltaC

199 tes discrete signaling cascades to produce a localized response.

200 s from across the brain revealed a similarly localized rhythm in the homologous deep posteromedial co

201 beta (+c) is the sum of angular width(s) of localized RNFL defect.

202 It is currently poorly understood whether localized S. aureus skin infections persistently alter t

203 These localized shifts toward hypoxia have identified a promin

204 fferentiation, as well as in systemic versus localized signaling.

205 the preparation of the spin-valley state of localized single holes.

206 ections can lead to diseases that range from localized skin abscess to life-threatening toxic shock s

207 f this stability mechanism also accounts for localized sounds.

208 circadian clock, here we report that nuclear-localized SPY, but not SEC, specifically modulates the p

209 ropometrics was consistently associated with localized Stage II/III periodontitis and a J-shaped asso

210 R >=0.50 were associated with higher risk of localized Stage II/III periodontitis than their counterp

211 ing nCounter technology was performed in 110 localized-stage and 556 advanced-stage FL patients.

212 To investigate the genetic background of localized-stage FL, patient cohorts with advanced-stage

213 L, patient cohorts with advanced-stage FL or localized-stage FL, uniformly treated within phase 3 tri

214 ic bound states from intrinsically many-body localized states are rare.

215 provide an unusual electronic platform with localized states for electrons and more disperse bands f

216 ports the experimental observation of highly-localized states.

217 h endows it with a low frontier gap and edge-localized states.

218 monolayer transition-metal dichalcogenides, localized strain can be used to design nanoarrays of sin

219 The localized structures that we observe share several prope

220 lin 3 E3 ligase complex to ubiquitinate SINC-localized substrates, such as EDS1 and specific WRKY tra

221 ve examined the distance- and size-dependent localized surface plasmon resonance (LSPR) between fluor

222 ective, simple and robust biosensor based on localized surface plasmon resonance and hybridization ch

223 tal bioaerosol concentration, we developed a localized surface plasmon resonance biosensor based on s

224 absorption could be observed because of the localized surface plasmon resonance that causes impedanc

225 By the photoexcitation of localized surface plasmon resonances of metal nanopartic

226 The localized surface plasmons (LSPs) on the NPG sheet, part

227 Furthermore, evidence of localized, surficial collapse, might reflect a complemen

228 nsverse relaxation rate (R2*) indicated that localized susceptibility enhancement in the habenula is

229 g root hair initiation and demonstrated that localized synthesis of flavonol antioxidants control the

230 had at least 1 true-positive PSMA PET lesion localized that corresponded with the reference standard.

231 Further, we localized the cortical sources and observed early strong

232 We determined the MAb cross-reactivities, localized the epitopes, and measured functional activiti

233 aneous and ajmaline-induced BrS, the CineECG localized the late QRS activity in the RVOT, a phenomeno

234 However, anti-E2 antibody localized the LIF receptor to areas of E2 expression on

235 spontaneous or ajmaline-induced BrS, CineECG localized the terminal mean temporospatial isochrone for

236 he endothelium has the potential to generate localized therapeutic effects at the blood-tissue interf

237 , and photothermal therapy, which results in localized thermal damage.

238 Here, a localized thermal managing strategy, thermal-disrupting

239 Using capillary microsampling, we localized these compounds to the xylem, which indicated

240 gamma-interferon-inducible lysosome/endosome-localized thiolreductase (GILT), and lymphocyte antigen

241 yte (TSK) population unique to cancer, which localized to a fibrovascular niche.

242 ontrast to a kinase-resistant version, which localized to active puncta that promote lysosomal-mediat

243 putative dominant negative missense variants localized to an electronegative pocket considered critic

244 electricity in LHPs, a charge carrier may be localized to and/or induce the formation of nanoscale do

245 The first, localized to bilateral Heschl's gyri and indexed by low-

246 tent with a repressive regulatory role, DDX3 localized to cytoplasmic puncta with SG marker PABP1 in

247 only NE maintains its catalytic ability when localized to DNA.

248 s, constitutively secrete paracrine activity localized to EVs which inhibits influenza infection of E

249 The candidate type III effector TarP, which localized to focal adhesions during infection and when e

250 de analyses also revealed that wild-type AID localized to MHCII genes, and AID expression correlated

251 terization showed that MTCH2 and MTCH2x were localized to mitochondria with a long t (1/2) (>36 h).

252 Several plant proteins are preferentially localized to one end of a cell, allowing a polarity to b

253 nose, hybrid and complex N-glycans that were localized to regions of mucus and alveolar-bronchiolar h

254 VWD mutation effects are localized to the A1 domain without appreciably affecting

255 1/IRG, the binding partner of EXC-9, is also localized to the apical membrane and affects apical acti

256 esults in the reduction of dynamics that are localized to the binding site.

257 and compartment specific (BAL vs. blood) and localized to the challenged lung segments.Conclusions: A

258 Cell-based assays showed that OsPHT2;1 localized to the chloroplast envelope and functioned as

259 Further, in mice, Klk7 expression was localized to the epidermis in both steady state and infl

260 DGK2 and DGK4 were localized to the ER and were involved in PA production f

261 Both variants localized to the ER, but the AtUPS5L variant was also de

262 iquitously expressed in plant tissues and is localized to the ER, Golgi apparatus, prevacuolar compar

263 Exudative retinal detachment (ERD) localized to the infratemporal periphery was present in

264 a(2+)-permeable, nonselective cation channel localized to the membranes of endosomes and lysosomes an

265 m scans because vitreoretinal separation was localized to the mid periphery.

266 This decrease was localized to the mitochondrial beta-oxidation pathway, a

267 GFP:EXO70A2 was localized to the nucleus and cytoplasm in developing pol

268 In interphase, NuMA is localized to the nucleus and hypothesized to control gen

269 In conclusion, the EBG is localized to the OB, is reliable, and follows response p

270 EXO70A2 also localized to the PT tip plasma membrane, consistent with

271 DRG and spinal cord in females, but remains localized to the sciatic nerve in males (tier 3).

272 t age effects on structure-function coupling localized to transmodal cortex in both cross-sectional d

273 CAR-NKT cells expanded in vivo, localized to tumors and, in one patient, induced an obje

274 EARP is localized to two distinct compartments related to its fu

275 imately one-fourth of these pause sites were localized to untranslated regions and could participate

276 e poorly characterized endoplasmic reticulum-localized transmembrane prolyl 4-hydroxylase (P4H-TM)-is

277 ggest that antigen-specific targeting of VAT-localized Treg cells could eventually be a strategy for

278 However, mitochondrially localized tRNAs were much less affected by the TbCAE abl

279 hanism of cAMP compartmentation utilized for localized tuning of an oscillatory circuit and has broad

280 In cases of congenital heart defects, localized ultrastructural disruptions that increase the

281 sensitive MRI sequences were identified and localized using susceptibility weighted imaging.

282 lly isolated clusters suggesting substantial localized variants.

283 In WT eggs, zinc was detected in cortically-localized vesicles which underwent exocytosis upon activ

284 We show that BASL is polarly localized when ectopically expressed in tobacco BY-2 cel

285 led increased expression of CCR2 that was co-localized with CD68(+) macrophages.

286 everal dozen genes where significant loci co-localized with either expression quantitative trait loci

287 autoimmune disease and inflammation, and co-localized with eQTLS and (genic enhancers of) of transcr

288 LEs upon PS-ASO treatment, and M6PR also co-localized with PS-ASOs in LEs or on LE membranes.

289 Areas of RNP identified on UWF FA images co-localized with RNP areas visualized on WF SS-OCTA images

290 It also co-localized with the disease-associated variant pS129-alph

291 QTL) for delta(13) C(leaf) were found and co-localized with transpiration, biomass accumulation, and

292 IK/SK channels co-localized with TRPV4(EC) channels at myoendothelial proj

293 These spin textures are localized within a half-wavelength of light, and exist o

294 Two-thirds of HRF were localized within a millimeter adjacent to the GA border.

295 auto-ubiquitination activity in vitro and is localized within distinct motile puncta in L. japonicus

296 We demonstrated that DNMT1 is not localized within mitochondria, but it is associated with

297 nules differentially controls fates of mRNAs localized within the same cytoplasmic domain.

298 a Notch reporter mouse, we discovered FCSCs localized within the TMJ superficial niche exhibit Notch

299 l cell walls, and PRP accumulation is highly localized within the walls of root cortical and vascular

300 tributed wrinkles tend to coalesce to form a localized wrinkle whose configuration depends on the ini