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1 imple polymer physics scaling laws valid for long chains.
4 tal findings that the CO stretching bands of long-chain acids appear at very similar energies when th
5 step in FAO is the transport of cytoplasmic long chain acyl-coenzyme A (acyl-CoA) into the mitochond
6 olipid biosynthesis, as an inhibitor of host long-chain acyl CoA synthetases, key enzymes for glycero
7 ial oxidative energy metabolism by restoring long-chain acyl CoA through ASCL1 activation and mechani
9 nother mitochondrial C(12) oxidation enzyme, long-chain acyl-CoA dehydrogenase (LCAD), also developed
11 ifically exhibit down-regulation of the very-long-chain acyl-CoA dehydrogenase (VLCAD) enzyme, which
13 mice decreased acetylation of mitochondrial long-chain acyl-CoA dehydrogenase, a known SIRT3 deacety
15 family 27 member 4, fatty acid synthase, and long-chain acyl-CoA synthetase (3), and glucose transpor
17 f cardiac lipotoxicity overexpressing ACSL1 (long-chain acyl-CoA synthetase 1) in cardiomyocytes, we
20 Recent findings indicate that inhibition of long-chain acyl-CoA synthetases with triacsin C, a fatty
21 nfrared microspectroscopy, the cutin mutants long-chain acyl-coenzyme A synthetase2 (lacs2), permeabl
24 P = .01, .04, and .05, respectively), and 1 long-chain acylcarnitine metabolite (palmitoyl carnitine
27 of CNS FAO results in robust accumulation of long-chain acylcarnitines in the brain, suggesting that
30 ticular waxes was mainly observed in primary long chain alcohols and, to a minor extent, in long-chai
31 ion channels, but where these sites are for long-chain alcohols and how they mediate a cutoff remain
33 drogenase 3a2 (Aldh3a2) enzyme that oxidizes long-chain aliphatic aldehydes to prevent cellular oxida
37 ncipient solidification states of models for long-chain alkanes cooled from a melt to an arrested sta
38 oc-protected amine, ester, protected sugars, long-chain alkanes, benzyl, 9-methylanthracenyl, and cho
39 Affimer characterization was achieved using long-chained alkanethiol linkers coupled with oligoethyl
41 nctions of the actin cytoskeleton by forming long chains along the two strands of actin filaments tha
47 Ls are commonly defined by the presence of a long-chain base (LCB) that is normally formed by the con
48 r of hydroxylation sites on the sphingolipid long-chain base and the fatty acyl moiety produces many
50 ng yeast-2-hybrid interaction, we identified LONG-CHAIN BASE KINASE1 (LCBK1) as an MEA-interacting pr
51 amide synthesis, serine palmitoyltransferase long-chain base subunit 1 (SPTLC1)/SPTLC2, decreased dex
54 acterize polyolefin microstructures, such as long-chain branching (LCB), but it suffers from low sens
55 his was explained in neonatal mice, in which long-chain, but not short-chain, Vi conjugate induced la
57 ium-chain (C10:1, C14:1) and polyunsaturated long-chain (C16:3) acyl-ACPs, indicating both the sensit
59 activity, this enzyme can use cellobiose and long-chain cellodextrins with a degree of polymerization
60 ng a single dose of radiation, long and very-long-chain ceramide species, and the expression levels o
65 little Acot activity, which was confined to long-chain CoAs and due mainly to Acot7 and Acot13 activ
68 ations revealed that the leachates contained long-chain compounds such as stearates or fatty acids, w
70 t, the insertion of ACs, in particular their long-chain counterparts, may trigger a nonspecific activ
71 ive technical mixtures of short-, medium- or long-chain CPs and featuring low or high chlorine conten
72 hemical will behave similarly to medium- and long-chain CPs as well as other persistent organic pollu
74 nal catalytic activities of SIRT6, including long-chain deacylation and mono-ADP-ribosylation of othe
75 a myristoylated peptide demonstrated lysine long-chain deacylation as an intrinsic SmSirt2 activity
76 ficiencies 2 orders of magnitude greater for long-chain deacylation than deacetylation against peptid
80 clusively for the dominating Dols, while for long-chain Dols, the relative input of the MEP and MVA p
84 anisms underlying protection include reduced long chain FA uptake, shifts in FA distribution (lipidom
86 dase 4 overexpression or acyl-CoA synthetase long chain family member 4 depletion diminishes necrosis
87 377del, containing genes Acyl-CoA Synthetase Long Chain Family Member 5 (ACSL5) and Zinc Finger DHHC-
89 n of 15-lipoxygenase and acyl-CoA synthetase long-chain family member 4 (enzyme that generates substr
90 trol the uptake of saturated and unsaturated long-chain FAs (LCFAs) into skeletal muscle and knockdow
91 he high-fat diet was enriched with saturated long-chain FAs (LCSFA-HFD), while the other group (n = 9
95 -translational lipid modification in which a long chain fatty acid covalently attaches to specific cy
96 -saturated, and variously branched short and long chain fatty acids (FAs) esterified to a glucose (ac
97 in the inability to transport acylated very long chain fatty acids (VLCFAs) into the peroxisome for
98 ect of altering the weight ratio (R) between long chain fatty acids and fatty alcohols on the oil foa
99 ptor drives adults to convert lipids to very long chain fatty acids and hydrocarbons for an anti-dehy
100 ther, dHNF4 directs their conversion to very long chain fatty acids and hydrocarbons, which waterproo
101 ted in decreased import of LPC esterified to long chain fatty acids into activated CD8(+) T cells, an
102 nd fatty acid composition, accumulating Very Long Chain Fatty Acids with industrial applications.
103 dratases are required for elongation of very long chain fatty acids, and HACD1 has a role in early my
108 bly form a complex that efficiently converts long chain fatty acyl-ACP/fatty acyl-CoA into hydrocarbo
109 nrichment of biological processes related to long chain fatty acyl-CoA biosynthesis and elongation of
110 al protein (TFP) catalyzes beta-oxidation of long chain fatty acyl-CoAs, employing 2-enoyl-CoA hydrat
111 twithstanding the distilling conditions, the long chain fatty ester content was significantly higher
112 chondrial membrane where it likely activates long chains fatty acids for import and degradation.
113 coenzyme A synthetase-1 (ACSL1) facilitates long-chain fatty acid (LCFA) uptake and activation with
114 e first and rate-limiting enzyme of the very-long-chain fatty acid (VLCFA) beta-oxidation pathway in
115 ype 12 (HSD17B12) as a human hub of the very-long-chain fatty acid (VLCFA) synthesis pathway and core
117 mission tomography with oral and intravenous long-chain fatty acid and glucose tracers during a stand
118 ons with apolar molecules; both hexane and a long-chain fatty acid belonging to the quorum-sensing sy
119 diminished capacity for carnitine-dependent long-chain fatty acid beta-oxidation in neural stem cell
123 etabolites) included elevated amino acid and long-chain fatty acid metabolites, and reduced hexose mo
124 e used (13)C-labeled glucose, glutamine or a long-chain fatty acid mixture added to cell culture medi
125 loss of an obligate enzyme in mitochondrial long-chain fatty acid oxidation, carnitine palmitoyltran
128 ts in an increase in phospholipids with very-long-chain fatty acid tails (PL-VLCFAs) that contain 26
129 lesterol acyltransferase, ACAT1) transfers a long-chain fatty acid to cholesterol to form cholesteryl
130 FAO by removing the inhibitory mechanism of long-chain fatty acid transport into mitochondria via de
131 d that oxidized LDL upregulated effectors of long-chain fatty acid uptake and mitochondrial import, w
133 ducts of dietary triacylglycerol, especially long-chain fatty acids (LCFAs) and 2-oleoyl-glycerol (2-
135 8+ T cells progressively accumulate specific long-chain fatty acids (LCFAs), which, rather than provi
136 binding to HSA in the same manner as native long-chain fatty acids (LCFAs), within hydrophobic pocke
139 nt study, we found that the contents of very long-chain fatty acids (VLCFAs) in akr2a mutants were de
140 h exacerbates accumulation of LCFAs and very-long-chain fatty acids (VLCFAs) that mediate lipotoxicit
141 ast fungus Magnaporthe oryzae, requires very-long-chain fatty acids (VLCFAs), which act as mediators
143 ccumulation of peroxisomal educts (like very-long-chain fatty acids [VLCFAs] or branched-chain fatty
144 leum also led to increased concentrations of long-chain fatty acids and L-lactate metabolites in the
145 ent mitochondrial model of beta-oxidation of long-chain fatty acids and main energy-redox processes i
146 igher concentrations of functional saturated long-chain fatty acids and short-chain fatty acids.
147 functions in both the transport of exogenous long-chain fatty acids and the activation of very-long-c
148 art and muscle reduced complete oxidation of long-chain fatty acids by 87 and 69%, respectively, with
149 owth was dependent on the uptake of haem and long-chain fatty acids during infection, but only in a s
150 ian brain oxidizes a substantial quantity of long-chain fatty acids in vitro and in vivo Loss of CNS
151 tions in ABCD1 lead to incorporation of very-long-chain fatty acids into phospholipids, we separately
152 OE seeds showed gain in triacylglycerols and long-chain fatty acids over the vector-transformed contr
153 mation, whereas supplementation with omega 3 long-chain fatty acids protect against intestinal inflam
154 tiation: ELOVL1, encoding elongation of very long-chain fatty acids protein 1, and SLC27A1, encoding
156 AP, however, exhibits a clear preference for long-chain fatty acids thereby limiting its broad applic
158 ver fatty acid-binding protein (LFABP) binds long-chain fatty acids with high affinity and is abundan
159 In a yeast strain engineered to produce very-long-chain fatty acids, CER1-LIKE1 interacted with CER3
161 ches, we show that the START domain binds to long-chain fatty acids, products of Them1's enzymatic re
162 ase (Geh), with specificities for short- and long-chain fatty acids, respectively, each with roles in
164 P450 BM3 binds and oxidizes several mid- to long-chain fatty acids, typically hydroxylating these li
165 noleic acid, odd-chain fatty acids, and very long-chain fatty acids, was associated with lower incide
168 also investigated two distantly related very-long-chain fatty acyl (VLCFA) desaturases from Arabidops
169 s is far greater against substrates carrying long-chain fatty acyl modifications such as myristoylate
170 tabolism and vacuolar morphology through the long-chain fatty acyl-CoA synthetase Faa1, independently
171 ember 2 (Them2) is a mitochondria-associated long-chain fatty acyl-CoA thioesterase that is activated
174 ntro leaf metabolites revealed that one, the long-chain fatty aldehyde (E)-2-dodecenal, activates mul
175 ce G protein-coupled receptor for medium and long-chained fatty acids that can be expressed as distin
176 otein-coupled receptor (GPCR) for medium and long-chained fatty acids, agonism of which can regulate
179 gth, typhoid conjugates made with short- and long-chain fractions of Vi polysaccharide with average s
180 ant increases in NAD(+), arginine, saturated long chain free fatty acids, diacylglycerides, triacylgl
183 ed in photoreceptor cells and generates very long chain (>/=C28) polyunsaturated fatty acids includin
187 rogenation of carbon monoxide (CO), produces long chain hydrocarbons and offers an alternative to the
189 the treatment can simultaneously remove both long-chain insulating surface ligands of oleic acid and
190 formed between charged micelles (i.e., from long chain ionic surfactants) and neutral cyclodextrins
191 capacity to generate necessary quantities of long chain (LC-) polyunsaturated fatty acid (PUFA)-conta
193 selectivities for the biphasic production of long-chain linear aldehydes under benign aqueous conditi
197 acyl chains showed a high occurrence of very-long-chain moieties; phytosphingosine and 4-hydroxy-8-sp
198 Cuticular wax is a mixture of aliphatic very-long-chain molecules, ranging from 22 to 48 carbons, pro
207 dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body w
209 Dietary intake and adipose tissue content of long-chain n-3 PUFAs were neither consistently nor appre
214 n sulfate (CS) and dermatan sulfate (DS) are long chains of repeating disaccharide units, covalently
215 han conventional management (+39% PUFA, +24% long chain omega-3 and +12% conjugated linoleic acid (CL
217 ies of the wall materials when encapsulating long chain omega-3 polyunsaturated fatty acids by electr
221 or psychosis is dietary supplementation with long-chain omega-3 polyunsaturated fatty acids (PUFAs).
222 id oxidation reactions of furan fatty acids, long-chain omega-3 polyunsaturated fatty acids, and toco
223 FF has historically contained high levels of long-chain per- and polyfluoroalkyl substances (PFAS), w
224 r, the concentrations of PFAS precursors and long-chain perfluoroalkyl acids (PFAAs) (>=6C for PFSAs
226 ed fraction was almost consistently >50% for long-chain perfluoroalkyl carboxylates and sulfonates (>
231 e, and concentrations of PFAA precursors and long chained PFAA in biota were positively correlated to
232 atively low drinking water concentrations of long-chain PFAAs substantially increase human body burde
237 and varied less (<0.5 log units) compared to long-chain PFASs (>0.5 to 1.5 log units) and zwitterions
238 hort-chain and alternative PFAS compounds to long-chain PFASs that have yet to be reported will also
239 on a limited selection of rather well-known long-chain PFASs, particularly perfluorooctanesulfonate
241 greater concentrations of PFASs, especially long-chain PFCAs, were found in seabirds breeding or for
243 lysis of polyphosphate (a group of important long-chained phosphate molecules) on aluminum oxides in
244 ultra-strong elastomers from biomass-derived long-chain polyamides by thiol-ene addition copolymeriza
245 a real-time numerical simulation model of a long chain polymer in the presence of histones and conde
247 orm macromolecular intermediate phases using long chain polymers, which leads to the formation of a p
250 al Escherichia coli sepsis is compromised by long-chain polyphosphates, and improves with bacterial p
254 arly stage accompanied by the dissolution of long-chain polysulfide, and solid-state transition from
255 Fish fed the CS diet had significantly more long chain polyunsaturated fatty acid than had those fed
256 ic acids, such as hydroxycinnamic acids, and long chain polyunsaturated fatty acids (PUFAs) omega-3 a
257 feeds reduces the levels of valuable omega-3 long chain polyunsaturated fatty acids such as eicosapen
259 Low-certainty evidence showed that omega-3 long-chain polyunsaturated fatty acid (LC-PUFA) was asso
262 sted that docosahexaenoic acid (DHA), an n-3 long-chain polyunsaturated fatty acid, might reduce the
263 etable-oil capsules that contained trace n-3 long-chain polyunsaturated fatty acids (control group) d
264 ized in the stroma, then converted into very-long-chain polyunsaturated fatty acids (FAs) at the endo
266 with the highest relative concentrations of long-chain polyunsaturated fatty acids (LC-PUFAs), while
268 sh-oil capsules that contained 900 mg of n-3 long-chain polyunsaturated fatty acids (n-3 group) or ve
269 e consistent with the selective transport of long-chain polyunsaturated fatty acids (PUFA) as well as
270 on of phospholipids containing 22:6 and very long-chain polyunsaturated fatty acids (VLC-PUFAs) in Ad
273 re data are needed regarding the role of n-3 long-chain polyunsaturated fatty acids in pregnancy.
274 ested that maternal supplementation with n-3 long-chain polyunsaturated fatty acids may reduce the in
276 onary advantage of genotypes enabling active long-chain PUFA synthesis when the introduction of agric
277 n stunting and low serum omega-3 and omega-6 long-chain PUFAs, which are essential for growth and dev
279 ins in membrane phospholipids and increasing long-chain saturated ceramides, changes previously linke
282 igher circulating concentrations of the very-long-chain SFAs (VLSFAs) arachidic acid (20:0), behenic
284 fides and speed up the reduction reaction of long chain sodium polysulfides to solid small chain poly
286 entrations of Tg and Tg analogs with various long-chain substitutions at the O-8 position extensively
288 multiple linear regression revealed that the long-chain-to-intermediate-chain acylcarnitine ratio inv
289 prene, E. ulmoides has evolved to synthesize long-chain trans-polyisoprene via farnesyl diphosphate s
291 Finally, we report that resting levels of long-chain triacylglycerols in mitochondrial myopathy co
292 h lower levels of mycolic acid wax ester and long-chain triacylglycerols than those for wild-type bac
294 , high lipid content, and especially omega-3 long chain unsaturated fatty acids, P. tricornutum exhib
299 ic transfer of 14 PFASs (5 short-chain and 9 long-chain) within the food web of the Yadkin-Pee Dee Ri
300 high colloidal stability achieved with this long-chain zwitterionic ligand can be rationalized with