ライフサイエンスコーパス: long-chain fatty acid

1 ondensation of a long chain base with a very long chain fatty acid.

2 inds at a structurally similar position to a long-chain fatty acid.

3 n antidiabetic GLP-1 analogue that carries a long-chain fatty acid.

4 sis and increasing import of cholesterol and long chain fatty acids.

5 e ABCD1 gene leading to accumulation of very long chain fatty acids.

6 large, multidomain protein that synthesizes long chain fatty acids.

7 ation capacity of mixed micelles formed from long chain fatty acids.

8 re higher than those of lipids consisting of long chain fatty acids.

9 related gene encoding GPR40, a receptor for long chain fatty acids.

10 h that was partially restored by addition of long chain fatty acids.

11 A cycle intermediates, and reduced levels of long chain fatty acids.

12 terized by the abnormal accumulation of very long chain fatty acids.

13 ity, with an apparent preference toward very long chain fatty acids.

14 ating step in the mitochondrial oxidation of long chain fatty acids.

15 mportant for mitochondrial beta-oxidation of long chain fatty acids.

16 thyroid hormone (T(3)), glucocorticoids, and long chain fatty acids.

17 ton transporting function in the presence of long chain fatty acids.

18 aturated fatty acids and a reduction in very long chain fatty acids.

19 2 function to synthesize long chain and very long chain fatty acids.

20 oprotein particles and facilitates uptake of long chain fatty acids.

21 also inversely associated with 7 unsaturated long-chain fatty acids.

22 m ACSs displayed substrate preference toward long-chain fatty acids.

23 d in the generation of metabolic energy from long-chain fatty acids.

24 with some molecular species containing very-long-chain fatty acids.

25 chain fatty acids and the activation of very-long-chain fatty acids.

26 f genes involved in the biosynthesis of very-long-chain fatty acids.

27 medium containing mycolic acid but not other long-chain fatty acids.

28 FadR, in agreement with induction of fadH by long-chain fatty acids.

29 significant differences in palmitic acid and long-chain fatty acids.

30 hat transports LPCs containing DHA and other long-chain fatty acids.

31 ed that AtLtpI-4 protein can bind these very-long-chain fatty acids.

32 t enabled the identification of the unusual, long-chain fatty acids 24:6, 26:6, 26:7, 28:7, and 28:8

33 exon six of a gene named Elongation of very long chain fatty acids 4 (ELOVL4).

34 mutations in the ELOVL4 (Elongation of very long chain fatty acids 4) gene.

35 Elongation of very long chain fatty acids-4 (ELOVL4) has been identified as

36 he metabolic regulator factors elongation of long chain fatty acids 7 (Elovl7) and cytochrome B5 redu

37 The ACSL5 gene plays a key role in long chain fatty acid absorption, a phenotype similar to

38 atory demyelination in the brain, where very-long-chain fatty acids accumulate within phospholipid fr

39 The combined effect is long-chain fatty acid accumulation, alteration of mitoch

40 down using RNA interference, which decreased long-chain fatty acid activation, inhibited anchorage-de

41 port protein 4 (FATP4), which each have very long-chain fatty acid acyl-CoA synthetase (VLCFA-ACS) ac

42 otein-coupled receptor (GPCR) for medium and long-chained fatty acids, agonism of which can regulate

43 ids that are assumed to mimic the endogenous long-chain fatty acid agonists.

44 Major cuticular wax compounds, such as very long-chain fatty acids, alcohols, alkanes, and ketones,

45 te a sphingosine head allylic alcohol with a long-chain fatty acid alkene that also bears an allylic

46 Therefore, formulating the long-chain fatty acid amide derivatives of nucleoside an

47 s have an in vivo effect for around 7 h, the long chain fatty acid analogues have an effect up to 48

48 metry (LC/MS) method for long-chain and very-long-chain fatty acid analysis and its application to (1

49 ter interface in presence of model saturated long chain fatty acid and alcohol surfactants, nonanoic

50 also showed reduced uptake of a fluorescent long chain fatty acid and reduced levels of long chain p

51 scribe the structure of CD36 in complex with long chain fatty acids and a CD36-binding PfEMP1 protein

52 ect of altering the weight ratio (R) between long chain fatty acids and fatty alcohols on the oil foa

53 ptor drives adults to convert lipids to very long chain fatty acids and hydrocarbons for an anti-dehy

54 ther, dHNF4 directs their conversion to very long chain fatty acids and hydrocarbons, which waterproo

55 dogenously by both saturated and unsaturated long chain fatty acids and that an altered glucagon axis

56 mission tomography with oral and intravenous long-chain fatty acid and glucose tracers during a stand

57 st time the detailed mode of binding of both long-chain fatty acid and synthetic agonist ligands at F

58 L1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids and contributes the majority of c

59 at2 mutant showed increased contents of very-long-chain fatty acids and decreased PUFA in TAG and the

60 d be expected to enhance the accumulation of long-chain fatty acids and glycolysis.

61 leum also led to increased concentrations of long-chain fatty acids and L-lactate metabolites in the

62 eceptor family A, is mediated by medium- and long-chain fatty acids and leads to amplification of glu

63 gene, which encodes a membrane receptor for long-chain fatty acids and lipoproteins, is a potentiall

64 ent mitochondrial model of beta-oxidation of long-chain fatty acids and main energy-redox processes i

65 is characterized by an accumulation of very long-chain fatty acids and partially impaired peroxisoma

66 Saturated long-chain fatty acids and phytosphingosine supplementat

67 igher concentrations of functional saturated long-chain fatty acids and short-chain fatty acids.

68 functions in both the transport of exogenous long-chain fatty acids and the activation of very-long-c

69 ScACC) is crucial for the production of very-long-chain fatty acids and the maintenance of the nuclea

70 dratases are required for elongation of very long chain fatty acids, and HACD1 has a role in early my

71 OleTJE binds avidly to a range of long chain fatty acids, and structures of both ligand-fr

72 in, inhibition of angiogenesis, transport of long-chain fatty acids, and clearance of apoptotic cells

73 Long-chain fatty acids are internalized by receptor-medi

74 ogenated aromatics and of short, medium, and long chain fatty acids, as well as in the biosynthesis o

75 ducing activity by accumulating less active, long-chain fatty acid ascaroside derivatives.

76 ch is responsible for the elongation of very long-chain fatty acids (at least 26 carbons).

77 ons with apolar molecules; both hexane and a long-chain fatty acid belonging to the quorum-sensing sy

78 cy is an inherited disorder of mitochondrial long-chain fatty acid beta-oxidation (FAO).

79 diminished capacity for carnitine-dependent long-chain fatty acid beta-oxidation in neural stem cell

80 otal white adipose, and marked impairment of long-chain fatty acid beta-oxidation.

81 y is the most common defect of mitochondrial long-chain fatty acid beta-oxidation.

82 zyme A derivatives using long-chain and very-long chain fatty acids, bile acids and bile acid precurs

83 y restrictive and probably distinct from the long chain fatty acid-binding site.

84 ovl proteins that mediate elongation of very-long-chain fatty acids, block or dramatically slow cleav

85 ndothelial cells causes accumulation of very long chain fatty acids, but much later than the immediat

86 art and muscle reduced complete oxidation of long-chain fatty acids by 87 and 69%, respectively, with

87 inear n-alcohols (C >/= 4) and extracellular long-chain fatty acids (C > 10) at higher efficiency tha

88 yzoites synthesized a range of long and very long chain fatty acids (C14:0-26:1).

89 alls and found a reduction in the amounts of long-chain fatty acids (C18:0) in the atltpI-4 mutant.

90 is led to a significant increase in the very-long-chain fatty acids C24 and C26 in the cuticular wax

91 longases that catalyze the synthesis of very long chain fatty acids (C24 to C26) required for ceramid

92 ells are devoid of ABCD1 and accumulate very long-chain fatty acids (C26:0 and C26:1).

93 Previous research has indicated that long-chain fatty acids can bind myoglobin (Mb) in an oxy

94 itting mitochondrial import and oxidation of long chain fatty acids, carnitine also functions as an a

95 In a yeast strain engineered to produce very-long-chain fatty acids, CER1-LIKE1 interacted with CER3

96 A gene predicted to encode a long-chain fatty acid CoA ligase (FACL), similar to enzy

97 e due to a mutation in a BL-04 gene encoding long-chain fatty acid coenzyme A (CoA) ligase.

98 showed an enrichment of 2-hydroxylated very-long-chain fatty acid-containing GIPCs and polyglycosyla

99 nd a second group, with higher linolenic and long-chain fatty acid contents.

100 irmed by mass spectrometry techniques, these long chain fatty acids could form two or three acyloxyac

101 -translational lipid modification in which a long chain fatty acid covalently attaches to specific cy

102 alogues which are N-terminal modified with a long chain fatty acid derivative.

103 Resolution is mediated in part by long-chain fatty acid-derived lipid mediators called spe

104 on of oil bodies, and delayed degradation of long-chain fatty acids during early seedling development

105 owth was dependent on the uptake of haem and long-chain fatty acids during infection, but only in a s

106 presence of protective mechanisms toward the long chain fatty acid effects in bacteria belonging to C

107 olipid pathway, such as deletion of the very long-chain fatty acid elongase, Sur4, suppress the osmot

108 The elongases of very long chain fatty acid (ELOVL or ELO) are essential in th

109 VLCFA synthesizing enzymes, elongase of very long chain fatty acids (ELOVLs) (1 and 3) in both cell t

110 The predominant mechanism by which long-chain fatty acids enter cells is still debated wide

111 ts a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the

112 ietary and bacteria-derived medium-chain and long-chain fatty acids exacerbate, whereas short-chain f

113 inally coexpressed proteins, which both bind long chain fatty acids (FA), are functionally distinct.

114 ultifunctional glycoprotein that facilitates long-chain fatty acid (FA) uptake by cardiomyocytes and

115 We showed that NLMs lost saturated very-long-chain fatty acid (FA; C24:0) SM in cancer cells and

116 e the importance of oxidation of blood-borne long-chain fatty acids (Fa) in the cardiomyocytes for co

117 -saturated, and variously branched short and long chain fatty acids (FAs) esterified to a glucose (ac

118 Long-chain fatty acids (FAs) act centrally to decrease f

119 functions in high-affinity tissue uptake of long-chain fatty acids (FAs) and contributes under exces

120 alpha-linolenic acid (ALA) to omega-3 (n-3) long-chain fatty acids (FAs) is mediated through FA desa

121 chondrial membrane where it likely activates long chains fatty acids for import and degradation.

122 ting the availability of this rich source of long-chain fatty acids for mitochondrial beta-oxidation

123 Mycolic acids are unique long chain fatty acids found in the lipid-rich cell wall

124 chain fatty acids were released faster than long chain fatty acids from milk fat emulsions; long cha

125 that cycloxygenase 2-derived metabolites of long-chain fatty acids function as endogenous activating

126 neral oil) on the bioavailability of a model long chain fatty acid (heptadecanoic acid) and lipophili

127 ted that it catalyzes omega-hydroxylation of long-chain fatty acids, implicating these molecules in s

128 Our data suggest that long-chain fatty acid import into mitochondria in adipos

129 inked to the (omega-1)-hydroxy group of very long chain fatty acid in bradyrhizobial lipid A.

130 tabolomics analysis, we found an increase in long-chain fatty acids in BMPR2 mutant mouse RVs compare

131 system responsible for the detection of free long-chain fatty acids in humans.

132 Cs and sterols and suggested a role for very-long-chain fatty acids in the interdigitation between th

133 ian brain oxidizes a substantial quantity of long-chain fatty acids in vitro and in vivo Loss of CNS

134 ACAD9 also retains enzyme ACAD activity for long-chain fatty acids in vitro, but the biological rele

135 impaired as degradation of unesterified very long-chain fatty acids in X-ALD and is abolished in Zell

136 called GPR120, which responds to medium and long chain fatty acids, including health-promoting omega

137 Importantly, aliphatic long-chain fatty acids, including biomass-derived compou

138 Whereas long-chain fatty acids, including the n3 and n6 essentia

139 oline species containing polyunsaturated and long-chain fatty acids, indicating the presence of matur

140 ted in decreased import of LPC esterified to long chain fatty acids into activated CD8(+) T cells, an

141 A carboxylase 2 (ACC2) inhibits the entry of long chain fatty acids into the mitochondria, we hypothe

142 mportation of docosohexaenoic acid and other long-chain fatty acids into fetal and adult brain and is

143 of etomoxir, which inhibits the transport of long-chain fatty acids into mitochondria and increases b

144 tions in ABCD1 lead to incorporation of very-long-chain fatty acids into phospholipids, we separately

145 e the transfer of long-chain as well as very-long-chain fatty acids into the apoplast, depending on t

146 without fatty acids, but in the presence of long-chain fatty acids is "switched on" as a proton tran

147 ion of the glucose transporter GLUT4 and the long chain fatty acid (LCFA) transporter CD36 from intra

148 recyclable, due to incomplete degradation of long chain fatty acids (LCFA) released during lipids hyd

149 Long chain fatty acids (LCFA) serve as energy sources, c

150 sis that PE is further degraded and that the long-chain fatty acid (LCFA) moieties of PE are complete

151 coenzyme A synthetase-1 (ACSL1) facilitates long-chain fatty acid (LCFA) uptake and activation with

152 of circulating nutrients such as glucose and long-chain fatty acids (LCFA) by the mediobasal hypothal

153 uggest an inherent efficacy of nonesterified long-chain fatty acids (LCFA) in suppressing T2D and bre

154 EVO hydrolysis, production, and oxidation of long-chain fatty acids (LCFA), glycerol, acetate, and hy

155 ontrol mice were supplemented with saturated long-chain fatty acids (LCFA).

156 Long chain fatty acids (LCFAs) are the preferred substra

157 herapeutic functions of HSA is the amount of long chain fatty acids (LCFAs) bound to HSA.

158 pled receptors (GPCRs) that are activated by long chain fatty acids (LCFAs).

159 ct in synthesis of unsaturated long and very long-chain fatty acids (LCFAs and VLCFAs) and depletion

160 ducts of dietary triacylglycerol, especially long-chain fatty acids (LCFAs) and 2-oleoyl-glycerol (2-

161 Free fatty acid receptors (FFARs) for long-chain fatty acids (LCFAs) and SCFAs are expressed i

162 Long-chain fatty acids (LCFAs) are used as a rich source

163 We report that long-chain fatty acids (LCFAs) enhanced differentiation

164 The accumulation of long-chain fatty acids (LCFAs) in non-adipose tissues re

165 Upon activation by long-chain fatty acids (LCFAs), UCP1 increases the condu

166 8+ T cells progressively accumulate specific long-chain fatty acids (LCFAs), which, rather than provi

167 associated with the accumulation of multiple long-chain fatty acids (LCFAs), with C47H85O13P (C36:4),

168 binding to HSA in the same manner as native long-chain fatty acids (LCFAs), within hydrophobic pocke

169 or a corresponding fraction of the saturated long-chain fatty acids (LCFAs).

170 of the fadBA5 operon by PsrA is relieved by long-chain fatty acids (LCFAs).

171 on of not only linear but also branched very-long-chain fatty acids, leading to production of the cor

172 occurs not only indirectly through elevated long chain fatty acid levels but also through direct act

173 Very long-chain fatty acid levels were partially restored in

174 Medium- and long-chain fatty acid levels were quantified in serum fr

175 he expression of the gene elongation of very long chain fatty acids-like 2, an enzyme needed for prod

176 induced gene 2a, Insig2a, elongation of very long chain fatty acids-like 3, Elovl3 and sterol 12alpha

177 brary, we have identified elongation of very long-chain fatty acids-like 1 (ELOVL1) and fatty acid tr

178 allelic mutations in the elongation of very-long-chain fatty acids-like 4 (ELOVL4), whereas recessiv

179 tions leading to the de novo biosynthesis of long-chain fatty acids, mainly palmitate.

180 We found very long chain fatty acids, medium chain acylcarnitines, and

181 ugh FATP4 deficiency primarily affected very long chain fatty acid metabolism, mutant fibroblasts als

182 estigate diseases known for abnormalities in long-chain fatty acid metabolism, e.g., the Sjogren-Lars

183 rough gluconeogenesis, glyoxylate cycle, and long-chain fatty acid metabolism.

184 etabolites) included elevated amino acid and long-chain fatty acid metabolites, and reduced hexose mo

185 e used (13)C-labeled glucose, glutamine or a long-chain fatty acid mixture added to cell culture medi

186 Bile and long chain fatty acids negatively regulate ToxT activity

187 rofile, capable of interacting with numerous long chain fatty acids of varying degrees of saturation.

188 growth in mucus and on plates containing the long-chain fatty acid oleate as the sole carbon source.

189 to increase and to sustain oxidation of the long-chain fatty acid oleate on reperfusion (1878+/-56 v

190 anaerobic digestion metatranscriptome after long chain fatty acids (oleate) exposure.

191 associated with increased unsaturated C(18) long-chain fatty acids (oleic acid and linoleic acid) re

192 attachment and removal of palmitate or other long-chain fatty acids on proteins has been hypothesized

193 Our findings implicate very-long-chain fatty acids or their derivative complex lipid

194 OE seeds showed gain in triacylglycerols and long-chain fatty acids over the vector-transformed contr

195 for the design of diets for the treatment of long chain fatty acid oxidation disorders, such as the t

196 art, recapitulating the phenotype of reduced long chain fatty acid oxidation in cardiac hypertrophy.

197 ors beyond malonyl CoA in the heart regulate long chain fatty acid oxidation via L-CPT1.

198 e I [L-CPT1]) is elevated in hearts with low long chain fatty acid oxidation, such as fetal and hyper

199 that ACAD9 knockout in HEK293 cells affected long-chain fatty acid oxidation along with Cl, both of w

200 termine if a primary defect in mitochondrial long-chain fatty acid oxidation disrupts hepatic insulin

201 sults expose UCP3 as a critical regulator of long-chain fatty acid oxidation in the stressed heart po

202 loss of an obligate enzyme in mitochondrial long-chain fatty acid oxidation, carnitine palmitoyltran

203 energy expenditure and induces inactivity in long-chain fatty acid oxidation-deficient mouse models.

204 ) in CPT1A, a key regulator of mitochondrial long-chain fatty-acid oxidation.

205 ost-translational covalent attachment of the long chain fatty acid palmitate common in lipid raft-ass

206 r a medium-chain fatty acid (octanoate) or a long-chain fatty acid (palmitate).

207 se accumulation of unbranched saturated very-long-chain fatty acids, particularly in brain and adrena

208 odel results suggested that precipitation of long-chain fatty acids, produced from EVO hydrolysis, wi

209 educed hepatic metabolism, there was reduced long chain fatty acid production and a 2.5-fold increase

210 ches, we show that the START domain binds to long-chain fatty acids, products of Them1's enzymatic re

211 mation, whereas supplementation with omega 3 long-chain fatty acids protect against intestinal inflam

212 19 and its target ELOVL7 (elongation of very long chain fatty acids protein 7) were identified as the

213 tiation: ELOVL1, encoding elongation of very long-chain fatty acids protein 1, and SLC27A1, encoding

214 The long-chain fatty acid receptor FFA4 (previously GPR120)

215 The long-chain fatty acid receptor FFAR1/GPR40 binds agonist

216 Long-chain fatty acid receptor GPR40 induces secretion o

217 GPR120 is a long-chain fatty acid receptor that stimulates incretin

218 Long-chain fatty acid receptors G-protein-coupled recept

219 One of these proteins, ceQORH, a long-chain fatty acid reductase, was analyzed in more de

220 GPR120 is a receptor of unsaturated long-chain fatty acids reported to mediate GLP-1 secreti

221 Long-chain fatty acids repress the virulence of the impo

222 till debated widely as it is unclear whether long-chain fatty acids require protein transporters to c

223 shown that larval oenocytes synthesize very-long-chain fatty acids required for tracheal waterproofi

224 ase (Geh), with specificities for short- and long-chain fatty acids, respectively, each with roles in

225 etwork is necessary for ileal propionate and long chain fatty acid sensing to regulate glucose homeos

226 These results illustrate how a single long chain fatty acid specifically controls lipid oxidat

227 Reduction of very-long-chain fatty acid sphingolipid levels leads in parti

228 to evaluate functional relevance of GPR40 on long-chain fatty acid-stimulated increases in [Ca(2+)]i

229 Importantly, oleic acid, but not other long chain fatty acids such as palmitate, increased the

230 ansferred to KasA and also incorporated into long chain fatty acids synthesized using a Mycobacterium

231 ts in an increase in phospholipids with very-long-chain fatty acid tails (PL-VLCFAs) that contain 26

232 numerous often-overlooked nutrients, such as long-chain fatty acids, taurine, and choline.

233 hway in Mycobacterium tuberculosis generates long chain fatty acids that serve as the precursors to m

234 We found that larvae produce two novel long-chain fatty acids that are attractive to other larv

235 ce G protein-coupled receptor for medium and long-chained fatty acids that can be expressed as distin

236 the wild type in the presence of short- and long-chain fatty acids, the growth of these bacteria is

237 -ketoacyl synthase (KAS) domains to assemble long-chain fatty acids, the KASIII domain for initiation

238 AP, however, exhibits a clear preference for long-chain fatty acids thereby limiting its broad applic

239 Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3

240 ch the product of a separate gene, activates long chain fatty acids to form acyl-CoAs.

241 lesterol acyltransferase, ACAT1) transfers a long-chain fatty acid to cholesterol to form cholesteryl

242 Here we describe how the association of long-chain fatty acids to a partially unfolded, extracel

243 esting essentiality may be linked to feeding long-chain fatty acids to FAS-II.

244 ases that includes Porcupine, which attaches long-chain fatty acids to Wnt proteins.

245 D36) plays an important role in facilitating long chain fatty acid transport.

246 FAO by removing the inhibitory mechanism of long-chain fatty acid transport into mitochondria via de

247 The OM long-chain fatty acid transporter FadL from E. coli is a

248 (submicromolar) substrate binding to the OM long-chain fatty acid transporter FadL from Escherichia

249 rates by the Escherichia coli outer membrane long-chain fatty acid transporter FadL.

250 Sm, a homolog of the Escherichia coli FadLEc long-chain fatty acid transporter.

251 , suggesting that enhanced synthesis of very-long-chain fatty acid/trihydroxy LCB ceramides promotes

252 P450 BM3 binds and oxidizes several mid- to long-chain fatty acids, typically hydroxylating these li

253 membrane scavenger receptor that facilitates long chain fatty acid uptake by muscle.

254 d that oxidized LDL upregulated effectors of long-chain fatty acid uptake and mitochondrial import, w

255 ese processes, as well as for stimulation of long-chain fatty acid uptake by adiponection and insulin

256 icant changes in basal or insulin-stimulated long-chain fatty acid uptake, lipid droplet size, or tri

257 of six FATPs that facilitate long- and very-long-chain fatty acid uptake.

258 rane proteins that facilitate long- and very long-chain fatty acid uptake.

259 of six FATPs that facilitate long- and very long-chain fatty acid uptake.

260 its translocation to the plasma membrane and long-chain fatty acid uptake.

261 provide insight into the regulation of very long chain fatty acid (VLCFA) biosynthesis in Brassica n

262 n of ALD gene (ABCD1) and the resultant very long chain fatty acid (VLCFA) derangement has dramatical

263 omal transmembrane protein required for very long chain fatty acid (VLCFA) metabolism.

264 rmalities in the transport of saturated very long chain fatty acids (VLCFA; >C18:0) contribute to the

265 e first and rate-limiting enzyme of the very-long-chain fatty acid (VLCFA) beta-oxidation pathway in

266 ses on the stem and leaf, except in the very long-chain fatty acid (VLCFA) class wherein acids longer

267 chefflera elegantissima) contained only very-long-chain fatty acid (VLCFA) derivatives such as alcoho

268 Notably, an unusual very-long-chain fatty acid (VLCFA) is found in the lipid A of

269 mplex are required for the synthesis of very-long-chain fatty acid (VLCFA) precursors of cuticular wa

270 usly undescribed desaturase activity on very-long-chain fatty acid (VLCFA) substrates and exhibit div

271 his study, we investigated the roles of very long-chain fatty acid (VLCFA) synthesis by fatty acid el

272 on initiation factor 2B (eIF2B) and the very-long-chain fatty acid (VLCFA) synthesis keto-reductase e

273 ype 12 (HSD17B12) as a human hub of the very-long-chain fatty acid (VLCFA) synthesis pathway and core

274 which catalyze two successive steps in very-long-chain fatty acid (VLCFA) synthesis.

275 ingolipids are synthesized de novo from very long-chain fatty acids (VLCFA) and sphingoid long-chain

276 noleukodystrophy is the accumulation of very long chain fatty acids (VLCFAs) due to impaired peroxiso

277 in the inability to transport acylated very long chain fatty acids (VLCFAs) into the peroxisome for

278 Among lipid species, the very-long-chain fatty acids (VLCFAs) are relatively rare and

279 The extension of very-long-chain fatty acids (VLCFAs) for the synthesis of spe

280 nt study, we found that the contents of very long-chain fatty acids (VLCFAs) in akr2a mutants were de

281 h exacerbates accumulation of LCFAs and very-long-chain fatty acids (VLCFAs) that mediate lipotoxicit

282 ast fungus Magnaporthe oryzae, requires very-long-chain fatty acids (VLCFAs), which act as mediators

283 luding fatty acid elongation to produce very-long-chain fatty acids (VLCFAs).

284 ccumulation of peroxisomal educts (like very-long-chain fatty acids [VLCFAs] or branched-chain fatty

285 In contrast, synthesis of very long chain fatty acids was primarily dependent on a fatt

286 noleic acid, odd-chain fatty acids, and very long-chain fatty acids, was associated with lower incide

287 Small percentages of other long chain fatty acids were also detected.

288 cluding oxidized low density lipoprotein and long chain fatty acids which involves the receptor in di

289 he upper surface of the petal is enriched in long-chain fatty acids, which are constituents of the wa

290 s with C16 fatty acids rather than with very-long-chain fatty acids, which are more commonly enriched

291 ing enzyme involved in the synthesis of very-long-chain fatty acids, which are precursors of epicutic

292 nd fatty acid composition, accumulating Very Long Chain Fatty Acids with industrial applications.

293 6) is necessary for the biosynthesis of very-long-chain fatty acids with chain lengths beyond C(2)(8)

294 98, and 136 Da allowed the identification of long-chain fatty acids with five or more double bonds.

295 ver fatty acid-binding protein (LFABP) binds long-chain fatty acids with high affinity and is abundan

296 re abundant intracellular proteins that bind long-chain fatty acids with high affinity.

297 d bioactive molecules that include amides of long-chain fatty acids with taurine [N-acyl-taurines (NA

298 ey exhibit high affinity binding of a single long-chain fatty acid, with the exception of liver FABP,

299 tterns of saturated and monounsaturated very-long-chain fatty acids, with the observed pattern consis

300 ld be insufficient to accommodate medium and long chain fatty acids without conformational changes in