ライフサイエンスコーパス: long-lasting

1 es cognitive impairments that are costly and long lasting.

2 fects within memory arise when adaptation is long lasting.

3 The efficacy of (+)-1 is long lasting.

4 effects of early adversity are likely to be long lasting.

5 against multiple influenza strains but also long-lasting.

6 ike those of other psychedelic compounds-are long-lasting(2), which has been attributed to its abilit

7 Key questions are how protective and long-lasting a vaccine needs to be, and how to target it

8 in centers, that processes information about long-lasting, absolute cold temperature in Drosophila.

9 man cardiovascular system and has remarkably long-lasting actions.

10 Nanoparticles caused a long-lasting activation of DOPr in endosomes, which prov

11 vironmental stressors induce the gradual and long-lasting activation of highly conserved cytoprotecti

12 eral human cancer cell lines in vitro with a long lasting activity.

13 administration in preclinical models induces long-lasting adaptations in reward and habit circuitry.

14 hat promotes viral persistence and generates long-lasting adaptive immunity.

15 icantly impact cortical development and have long-lasting adverse effects on neurodevelopmental outco

16 eous atrial ectopy to paroxysmal and finally long-lasting AF.

17 strates that adolescent THC exposure induces long-lasting affective and cognitive abnormalities, meso

18 by a standard 254 nm lamp and emit intense, long-lasting afterglow at 265-270 nm, which can be clear

19 Live infection provided strong, long-lasting Ag presentation that persisted through the

20 mune behavior, including the ability to form long-lasting, Ag-specific memories of a wide variety of

21 This pheromone enables rapid, long-lasting aggregation of termite workers, which contr

22 ) on postnatal days 7, 9, and 11] results in long-lasting alterations in synaptic transmission and re

23 The antibodies generated were long lasting and boostable and could recognize multiple

24 DAMGO-induced suppression of inhibition was long lasting and not reversed on washout of DAMGO or by

25 g fear responses; moreover, such effects are long lasting and resistant to renewal and spontaneous re

26 Accumulation of macrophages is long-lasting and detectable even in animals with mild or

27 Treatment of long-lasting and late diagnosed infection is difficult a

28 species, such as anthropoid primates, where long-lasting and obligate parental care is required for

29 release at the neuromuscular junction causes long-lasting and potentially fatal flaccid paralysis-a m

30 Then interestingly, a long-lasting and robust negative optokinetic afternystag

31 going and future PCP studies is fundamental, long-lasting and transformative.

32 ntribute to the infectious reservoir, may be long lasting, and require more sensitive diagnostics to

33 ide derived from mycobacterial Cpn60.1 has a long-lasting anti-inflammatory and immunomodulatory acti

34 oparticles is further improved, leading to a long-lasting anti-PDAC effect in vivo.

35 ruses belonging to the same serogroup and by long-lasting antibodies from prior infections.

36 ce immunized with RBD-NVP induced robust and long-lasting antibody responses against RBD from SARS-Co

37 ramidal cells in the mPFC produces rapid and long-lasting antidepressant and anxiolytic responses.

38 Subanesthetic ketamine evokes rapid and long-lasting antidepressant effects in human patients.

39 eceptor antagonist, which produces rapid and long-lasting antidepressant effects in patients with maj

40 receptor antagonist(2,3), provide rapid and long-lasting antidepressant effects in these patients(4-

41 receptor agonist 8-OH-DPAT induces rapid and long-lasting antidepressant-like effects in the forced s

42 Demand for long-lasting antifouling surfaces has steered the develo

43 These data suggest that the long-lasting antitumor effect of the prodrug is due to a

44 lecules on tumor cells, can mediate deep and long-lasting antitumor responses in patients with solid

45 atic melanoma by increasing the frequency of long-lasting antitumor responses.

46 nd adaptive immune systems elicit strong and long lasting antitumour immunity which prevents tumour f

47 r, rapid clearance of the glioblastoma and a long-lasting antitumour memory response.

48 some rodent species, produced in male rats a long-lasting anxiety-like state that was measured 7 days

49 Our goal here is to develop a long-lasting approach that provides immunoprophylaxis fo

50 c plasticity that underlies the formation of long-lasting associative memories for environmental cues

51 These findings reveal how long-lasting attenuation of signal transduction by degra

52 Long-lasting B-cell memory has been shown to occur in re

53 ents in each SPN subtype and their impact on long-lasting behavioral adaptations.

54 of the HAB toxin domoic acid (DomA) produces long-lasting behavioral deficits in rodent and primate m

55 focus on eliminating these cells to promote long-lasting benefit.

56 Systemic acquired resistance (SAR) is a long-lasting broad-spectrum plant immunity induced by mo

57 ls, highlighting the challenges in achieving long-lasting, broad protection against an ever-evolving

58 et of the rains, whereas that of typhoid was long-lasting but with a two months delayed start, implyi

59 The impacts of grief are long-lasting, but support from colleagues provides some

60 ent of cost-effective, efficient, stable and long-lasting catalysts.

61 associated with IL-6 levels in plasma, and a long-lasting CD11b(+)CD16(+) cell population.

62 se of cyto/chemokines and the development of long-lasting CD8 T cells, which in turn causes the recru

63 C kinase activity, to establish and maintain long-lasting cellular and behavioral alterations followi

64 Our study has overcome long lasting challenge of inducing endovascular stroke m

65 A long-lasting challenge in neuroscience has been to find

66 ed if juvenile ketamine treatment results in long-lasting changes for the rewarding properties of suc

67 derlie persistent activity and contribute to long-lasting changes in behavior.

68 -synthesizing neurons, little is known about long-lasting changes in DA cells that may contribute to

69 FD) feeding during lactation in mice elicits long-lasting changes in gene expression in the offspring

70 STATEMENT Early life inflammation results in long-lasting changes in many aspects of adult physiology

71 compared to SRGAP2B in its ability to induce long-lasting changes in synaptic density throughout adul

72 during LTF in Aplysia SIGNIFICANCE STATEMENT Long-lasting changes in synaptic plasticity associated w

73 tors modulate the release machinery, causing long-lasting changes in synaptic transmission that influ

74 Some of these studies have documented long-lasting changes in the expression of epigenetic enz

75 including substance abuse and stress, cause long-lasting changes in the regulation of gene expressio

76 The results reveal long-lasting changes in vlPAG/DR threat responding resul

77 factor contributing to the establishment of long-lasting chronic bacterial infections.

78 In addition, long-lasting clinical benefits from single-agent therapi

79 fficient one-time treatment that can provide long-lasting clinical improvement and at the same time p

80 fy often-conflicting criteria, which include long-lasting coherence and scalable control(1).

81 is intracellular bacterium is able to regain long-lasting colonization in gamma interferon (IFN-gamma

82 racellular bacterium Chlamydia maintains its long-lasting colonization in the colon by evading IFN-ga

83 g the mechanisms by which bacteria establish long-lasting colonization in the gastrointestinal tract

84 ine receptor CCR6, showed full rescue of the long-lasting colonization of the mutant, indicating a ro

85 bacterial mutant without fully rescuing the long-lasting colonization of the mutant.

86 muridarum can reach the colon and maintain a long-lasting colonization there.

87 Long-lasting confusion and memory difficulties during th

88 nes, Tfh cells are much more static, forming long-lasting conjugates.

89 Few phenomena have had as profound or long-lasting consequences in human history as the emerge

90 acid (PUFA) intake on neurodevelopment with long-lasting consequences on behavior.

91 CE STATEMENT Early-life stress (ELS) induces long-lasting consequences on stress responses and emotio

92 eatment at any stage of development can have long-lasting consequences.

93 Long-lasting, consolidated memories require not only pos

94 uited outside the white pulp; 2) followed by long-lasting contacts (12 to 24 h) between iNKT cells, D

95 rentially expressed proteins, and produces a long-lasting correction of somatosensory circuit functio

96 However, behavioural determinants leading to long lasting corticospinal plasticity and motor expertis

97 the acute phase as well as long COVID, i.e. long-lasting COVID-19 symptoms, in patients from the Far

98 The origin of turtles is one of the most long-lasting debates in evolutionary research.

99 This large and long-lasting decrease in evoked activity is consistent w

100 d with the inability of ketamine to induce a long-lasting decrease in inhibitory neurotransmission.

101 We show that LV-LDLR produced a significant long-lasting decrease in total serum cholesterol whereas

102 It remains unclear, however, whether the long-lasting deficits attributed to MD during the critic

103 These findings show GEE induces long-lasting deficits in cognitive function that may con

104 errupt the vicious circle that maintains the long-lasting deleterious effects of the reciprocal inter

105 erapy), generally alleviates pain and allows long-lasting dental function.

106 ynchronization and engagement, rewards had a long-lasting desynchronizing effect.

107 Similarly, in Experiment 3, no long-lasting differences in these measures were observed

108 depend on willingness of individuals to make long-lasting difficult dietary changes, but on the avail

109 Severe brain injuries can lead to long-lasting disorders of consciousness (DoC) such as ve

110 To avoid creating long-lasting disparities between UAMs who are placed in

111 demonstrate that critical-period MD produces long-lasting disruptions in binocular integration beginn

112 C differentiation, with transient as well as long-lasting DNAm changes.

113 ut those events did not alleviate severe and long-lasting droughts.

114 ught to be one of the cellular substrates of long-lasting drug-associated memories.

115 OCA exerted a more potent and long-lasting effect, mainly related to modulation of col

116 in patients with menopause and could have a long-lasting effect.

117 ity in the mPFC during the P2-P14 period had long lasting effects on adult emotional behaviours and o

118 Early-life conditions can have long-lasting effects and organisms that experience a poo

119 In mice, these long-lasting effects are associated with long-term anti-

120 These long-lasting effects are attributed to downstream signal

121 peptide Y (NPY) is uniquely required for the long-lasting effects of AgRP neurons on feeding behavior

122 Long-lasting effects of malnutrition in early life can b

123 6.Conclusions: These findings underscore the long-lasting effects of the fetal origins of asthma, sup

124 ntal critical periods (CPs) has profound and long-lasting effects on cortical sensory processing perd

125 ogenetic disruption of this encoding induced long-lasting effects on downstream PVT-NAc cue responses

126 al studies have shown that nicotine produces long-lasting effects on gene expression within many brai

127 ight interfere with these processes and have long-lasting effects on health.

128 It has no obvious long-lasting effects on major periodontopathogens in the

129 ges in neuromodulation can have a variety of long-lasting effects on neural processing and behavior.

130 h as infant body mass, are predicted to have long-lasting effects on offspring fitness.

131 These decisions may have long-lasting effects on the environment, and therefore,

132 me oral treatments, such as cladribine, have long-lasting effects on the immune system, the cumulativ

133 The drug showed unusual long-lasting effects, as rats gradually stopped self-adm

134 microglia-neuron crosstalk pathways and have long-lasting effects, both at transcriptional and behavi

135 Some researchers have suggested long-lasting effects.

136 The intention to forget can produce long-lasting effects.

137 netic factors play a significant role in its long-lasting effects.

138 ntermittent hypercapnic hypoxia (IH) induces long-lasting elevations in sympathetic vasomotor outflow

139 abdovirus, or arenavirus infection induced a long-lasting enhancement of immunological memory that co

140 eir formation and continuous enrichment in a long-lasting environment.

141 ular mediators of these effects, focusing on long-lasting epigenetic changes.

142 n in the hippocampus, resulting in vivid and long-lasting episodic memories.

143 ch transform single mossy fiber signals into long-lasting excitation or inhibition respectively, and

144 have been relatively common and occasionally long-lasting features of interglacials.

145 propose that turbulent coherent structures, long-lasting flow patterns which trap particles, may ser

146 Herein, we report the first steps to create long-lasting (for tens of minutes) hyperpolarized state

147 ity carried forward into sleep, suggesting a long-lasting form of neural plasticity.

148 endent long-term depression (NMDAR-LTD) is a long-lasting form of synaptic plasticity.

149 Long-lasting forms of postsynaptic plasticity commonly i

150 Long-lasting geographic isolation between glacial refugi

151 tive stress with neuroinflammatory and their long-lasting harmful consequences.

152 ide perovskites is reported and their use as long-lasting high-temperature and high-input-power durab

153 Release of neuropeptides requires long-lasting, high levels of cytosolic Ca(2+) However, t

154 We observed a long-lasting, homeostatic depression of intrinsic excita

155 ation in the gamma frequency range lead to a long-lasting hyperpolarization (LLH) of the GCs with a d

156 rtain lineages, however, are able to sustain long-lasting immortality, as prominently exemplified by

157 effective vaccines that can elicit a robust, long-lasting immune response.

158 i-Ebola virus vaccine candidates that elicit long-lasting immune responses and can be delivered to vu

159 d domains of the virus to induce broader and long-lasting immune responses.

160 sed vaccines often fail to elicit potent and long-lasting immune responses.

161 sicles provoke significantly more potent and long-lasting immune stimulation in terms of interferon e

162 of these vaccines promises to deliver solid, long-lasting immunity after a single dose.

163 emory can persist long-term, contributing to long-lasting immunity after infection or vaccination.

164 develop a vaccine against ZIKV that elicits long-lasting immunity; however, the durability of immuni

165 These findings support the hypothesis of a long-lasting impact of CM on the biological epigenetic r

166 This may point toward a more long-lasting impact of doxycycline treatment on memory p

167 t provide the biological explanation for the long-lasting impact of metabolic alterations of diabetic

168 We additionally discuss the potential long-lasting impact of the pandemic on cancer care due t

169 communities, but also soil communities has a long-lasting impact on the trajectory of community assem

170 and accelerate the ability to innovate with long-lasting impact.

171 ocean, marine heatwaves, can have severe and long-lasting impacts on marine ecosystems, fisheries and

172 fect on decomposition reported here may have long-lasting impacts on nutrient cycling, soil organic m

173 e, stochastic colonization in early life has long-lasting impacts on the development of animal microb

174 shows that grassland-to-crop conversion has long-lasting impacts on the functional biodiversity of a

175 Medical complications are associated with long-lasting impairments and worsening HRQOL, whereas th

176 resholds have returned to normal, reflecting long-lasting impairments to the auditory CNS.

177 tions, such that early-life experiences have long-lasting implications for cognitive and emotional fu

178 sions during a perinatal time window leave a long-lasting imprint on the human T cell repertoire, whi

179 BMM s and SOCS3 expression is pronounced and long lasting in T cells.

180 This enhanced dopamine signal accompanies a long-lasting increase in conditioned behavioral respondi

181 We find that an EP2 agonist caused long-lasting increases in CREB phosphorylation and COX-2

182 Conversely, extinction training induced long-lasting increases in MMP-2 activity adjacent to D2-

183 Intermittent hypoxia leads to long-lasting increases in muscle sympathetic nerve activ

184 of the helminths prior to their establishing long-lasting infections in the host.

185 Early-life experience has a long-lasting influence on social behaviour.

186 We conclude that selective and long lasting inhibition of the rostral anterior cingulat

187 vivo treatment with norBNI does not produce long-lasting inhibition of KOR regulation of dopamine re

188 Hypothalamic melanocortins have a potent and long-lasting inhibitory effect on feeding and anabolism,

189 of insecticide-based control tools including long lasting insecticidal nets (LLINs).

190 most important vector control interventions-long-lasting insecticidal nets (LLINs) and indoor residu

191 Long-lasting insecticidal nets (LLINs) are believed to h

192 Long-lasting insecticidal nets (LLINs) are the primary m

193 ting behaviour over 4 years following a mass long-lasting insecticidal nets (LLINs) distribution in T

194 xposure to pyrethroid based products such as long-lasting insecticidal nets (LLINs) has created mosqu

195 Two billion long-lasting insecticidal nets (LLINs) have been procure

196 ury have been largely due to distribution of long-lasting insecticidal nets (LLINs)(5), with many SSA

197 spraying (IRS), programmatically distributed long-lasting insecticidal nets (LLINs), and standard cas

198 efficacy of conventional and next-generation long-lasting insecticidal nets (LLINs), determined resis

199 egative women currently relies on the use of long-lasting insecticidal nets together with intermitten

200 -negative pregnant women with high uptake of long-lasting insecticidal nets, IPTp-DP is cost-effectiv

201 ed net, only 36.6% reported sleeping under a long-lasting insecticide-treated net (LLIN) the previous

202 ill needed for effectively provide rapid and long-lasting interventions.

203 Long-lasting, latently infected resting CD4(+) T cells a

204 arly Triassic faunas, suggesting a potential long-lasting Lilliput effect in this fauna.

205 ed how the brain encodes information to form long-lasting memories that lead to stable changes in beh

206 e, the infant hippocampus is able to produce long-lasting memories.

207 g (CPEB) protein, is a putative substrate of long-lasting memories.

208 onstration that reconsolidation can underpin long-lasting memory improvements may both provide an und

209 in the development of high-affinity Abs and long-lasting memory to foreign Ags.

210 d also be conducted to determine the risk of long-lasting metabolic consequences after maternal trans

211 Only two products (Replens Long-Lasting moisturizer and Trimo-San) significantly in

212 Silky Smooth lubricant, coconut oil, Replens Long-Lasting moisturizer or Trimo-San) on growth and via

213 es fast actions, supra-linear responses, and long-lasting molecular switches.

214 nd survival proteins, early exercise induces long-lasting morphological changes in cortical and hippo

215 ese responses opens up new possibilities for long-lasting, multilayered tumour control.

216 eness of sensory stimulation by activating a long-lasting muscarinic cation current in motoneurons.

217 area during childhood and adolescence has a long-lasting negative association with mental health irr

218 l plantations are consistently vulnerable to long-lasting negative effects on fundamental ecosystem c

219 We include discussions of large-scale, long-lasting neural recording; wireless, miniaturized im

220 Prior exposure to abused drugs leads to long-lasting neuroadaptations culminating in excessive d

221 tnatal ZIKV infection in this model may have long-lasting neurodevelopmental consequences.

222 NR1 ABs caused long-lasting neuropathological effects also in aged mice

223 ced acute peripheral pain and the subsequent long-lasting neuropathy.SIGNIFICANCE STATEMENT The first

224 activation of GABAergic VTA neurons elicited long-lasting non-rapid-eye-movement-like sleep resemblin

225 ish that acquired pOKR were found to exhibit long-lasting optokinetic after nystagmus (OKAN) as oppos

226 Furthermore, EMPs gave rise to long-lasting osteoclast precursors that contributed to p

227 astomose to the host circulation and exhibit long-lasting patterning, with no evidence of malformatio

228 Visual perceptual learning (VPL) can lead to long-lasting perceptual improvements.

229 We previously identified that long-lasting periods of severe postictal hypoperfusion/h

230 the relative value of available options with long-lasting persistent activity states during naturalis

231 l biopsies from 121 patients with persistent/long-lasting persistent AF (group 1; 59 males; 60+/-11 y

232 itionally find that pC1d/e activation drives long-lasting persistent neural activity in brain areas a

233 n the crosslinked HD/Se hydrogel network and long lasting photothermal efficacies can be maintained f

234 These stressors can result in long-lasting physical and mental health sequelae.

235 Us, a growing number of survivors experience long-lasting physical impairments.

236 tically ill patients with COVID-19 will face long-lasting physical, cognitive and/or mental health im

237 ICU survivors suffer from long-lasting physical, mental, and cognitive health impa

238 lbumin (PV)-positive interneurons (PVI), and long-lasting physiological and behavioral changes.

239 s or brief depolarizing current steps led to long-lasting plateau potentials and persistent firing (P

240 pic glutamate receptor activation triggering long-lasting plateau potentials thought to be mediated b

241 c core dopamine 1 (D1)-MSN activation causes long-lasting potentiation of excitatory transmission (LL

242 lly, excessive alcohol consumption induced a long-lasting potentiation of glutamatergic transmission

243 Levels of long-lasting, pp65-specific T cells with effector memory

244 Deep sclerectomy is an effective, long-lasting primary surgical procedure for OAG.

245 Catecholamines induce long-lasting proinflammatory changes in monocytes in vit

246 iver metastases in ~50% of mice and provided long-lasting protection against tumor recurrence.

247 reatments for allergy are that AIT induces a long-lasting protection and prevents the progression of

248 hat vaccine boosters are required to provide long-lasting protection.

249 wledge-based vaccines that elicit strong and long-lasting protective immune responses against HIV-1 i

250 y T cells at barrier tissues is critical for long-lasting protective immune responses.

251 ent and interrupted morphine exposure caused long-lasting psychomotor sensitization.

252 ssociation between cannabis use and acute or long-lasting psychosis are not completely understood.

253 rest functioning due to global change and/or long-lasting recovery from past disturbance.

254 Thus, long lasting reduction of spasticity by a-tsDCS via down

255 that involves a protein-synthesis-dependent long-lasting reduction in GABA release.

256 silencing of the transplanted neurons and a long-lasting reduction in spontaneous seizures.

257 y help people build goodwill needed for more long-lasting relationships.

258 salazine monotherapy has led to a remarkable long-lasting remission with complete resolution of all i

259 first dental adhesive to provide strong and long-lasting resin-dental collagen bonding without the a

260 dered a valid option, resulting in rapid and long-lasting resolution of RD.

261 lect ongoing cortical immune activation or a long-lasting response to a prenatal immune-related insul

262 r modeling, it is determined herein that the long-lasting response to a single exposure can originate

263 ell effector function with ACT could lead to long lasting responses.

264 rotein kinase (MAPK) signaling may result in long-lasting responses in patients with advanced melanom

265 tunity to target this population to induce a long-lasting reversal of disease.

266 Long-lasting, romantic partnerships are a universal feat

267 The achievement of long-lasting, safe treatments for food allergy is depend

268 hich biologically active molecules stored in long-lasting secretory granules (SGs) are secreted in re

269 Noxious stimuli evoke a range of acute and long-lasting sensations, emotions, and behaviors.

270 These studies demonstrate long-lasting, sex-dependent phenotypes produced by AIE a

271 s for robust GC maturation and generation of long-lasting SIV-specific humoral responses at mucosal a

272 urban species, and add to the evidence that long-lasting social associations can persist in fission-

273 In particular, the presence of long-lasting social ties has been highlighted as a hallm

274 the conflict species to derive effective and long-lasting solutions.

275 Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibitory control of neuropathic pa

276 suggestive of a high degree of isolation and long-lasting stability of the insular populations.

277 Animal behaviors are commonly organized into long-lasting states that coordinately impact the generat

278 ly: Lockdown measures caused substantial and long-lasting structural changes in the mobility network.

279 lation of local PV(+) interneurons induces a long-lasting suppression of GABAergic synaptic transmiss

280 First, mu-opioids induce a long-lasting suppression of inhibitory synaptic transmis

281 mice with allergy, anti-IL-4Ralpha provided long-lasting suppression of the IgE recall response beyo

282 trolled rhinitis despite medications or with long-lasting symptoms, on skin tests or the presence of

283 kinase Cs (PKMs) maintain distinct forms of long-lasting synaptic changes, even when both forms are

284 opamine receptors promoted the generation of long-lasting synaptically evoked "up-states" in matrix S

285 training only during early adulthood induces long-lasting systemic benefits that in several cases are

286 plications for the design of next-generation long-lasting therapeutics.

287 effective, pre-existing immune response to a long-lasting, therapy-induced immune response at all sit

288 ow-frequency neural oscillations preserved a long-lasting trace of sensory information through neural

289 glucose intolerance, fetal macrosomia, and a long-lasting transgenerational alteration in glucose hom

290 3 degrader capable of producing complete and long-lasting tumor regression in mouse xenograft models.

291 SD-36 achieves complete and long-lasting tumor regression in multiple xenograft mous

292 SD-36 achieves complete and long-lasting tumor regression in the Molm-16 xenograft t

293 cycles of a fasting-mimicking diet promotes long-lasting tumour regression and reverts acquired resi

294 ifficult-to-treat condition characterized by long-lasting urticarial rashes and histopathologic findi

295 face ECG waveforms and effect of ablation in long-lasting VF in patients with left assist devices.

296 Long-lasting VF may be modified or even terminated by ab

297 Continuous 12-lead ECG of 5 episodes of long-lasting VF occurring in 3 patients with left ventri

298 ation of tissue-associated, non-replicating, long-lasting viral reservoirs that are refractory to the

299 adolescence, but not later periods, produces long-lasting visual attentional behavior deficits, and r

300 nervous system (CNS) malignancies are often long-lasting without any clinical recourse.