ライフサイエンスコーパス: long-lived

1 A" ground state in which the HNCO(2+) ion is long lived.

2 dysfunction and damage, birds are remarkably long-lived.

3 presence of multiple folded states that are long-lived (~100 s) and reversible.

4 In addition, a long-lived (4.3 mus) intermolecular charge separation is

5 sian tektites lies buried beneath lavas of a long-lived, 910-km(3) volcanic field in Southern Laos: 1

6 r less and generated few CD4 memory cells or long-lived Ab-producing B cells.

7 ransition metal dichalcogenides are tunable, long lived, able to sustain field intensity enhancement

8 The bulk of the pancreas primarily comprises long-lived acinar cells that are not considered a bona f

9 nuclear fission can be enabled by recycling long-lived actinide isotopes within the nuclear fuel cyc

10 This long-lived activation enables iterative enzymatic assemb

11 urrent models posit that postnatally arising long-lived adult MSCs replace transient embryonic progen

12 sine122-beta2, to trap wild-type alpha2 in a long-lived alpha2beta2 complex.

13 antigen-experienced CD8(+) T cells that are long-lived and can rapidly differentiate into effector c

14 Our results suggest that the formation of long-lived and disorder-free charge-transfer states in t

15 ment relies on an underlying network of both long-lived and dynamic microtubules that provide structu

16 tion against malaria, yet the development of long-lived and effective humoral immunity against Plasmo

17 These results reveal a long-lived and globally extensive mantle reservoir that

18 reting effector memory T cells but remain as long-lived and hyperproliferative T cells.

19 single molecule imaging capable of detecting long-lived and mobile associations to measure their stoi

20 red to as the "Tree of Life", is a majestic, long-lived and multipurpose tree of sub-Saharan Africa.

21 Memory B cells (MBCs) are long-lived and produce high-affinity, generally, class-s

22 It is unclear whether these cells, which are long-lived and rarely renew, manage to preserve homeosta

23 y exhibit a mixture of patterns expected for long-lived and short-lived animals, and between income a

24 ing the detrimental effects of aging in this long-lived animal.

25 rive the ontogeny of migratory strategies in long-lived animals with slow maturation remain enigmatic

26 over time-scales of months or even years in long-lived animals, but the mechanisms leading to these

27 ant deviation from the average for short- or long-lived animals.

28 nd that short lived-animals aged faster than long-lived animals.

29 t channels, delayed electron emission from a long-lived anionic state and dissociative photodetachmen

30 se in the extrafollicular antibody response, long-lived antibody production, and the emergence of pub

31 us HIV-1 vaccination requires elicitation of long-lived antibody responses.

32 e generation of both TI-2 memory B cells and long-lived antibody secreting cells.

33 t form in response to vaccination, producing long-lived antibody secreting plasma cells and memory B

34 icit robust interferon-gamma (IFN-gamma) and long-lived antibody-secreting cell (ASC) responses, the

35 ILC2 in the aged brain are long-lived, are relatively resistant to cellular senesce

36 has been proposed that, due to the possibly long-lived biochemical nature of their components, PNNs

37 dividual monitoring dataset (1988-2012) on a long-lived bird to quantify transients, and we use a lif

38 This is particularly true for long-lived birds with multi-year, socially monogamous pa

39 Long-lived BM resident plasma cells constitutively secre

40 mablast-mediated humoral responses; however, long-lived bone marrow (BM) resident PCs (LLPCs) demonst

41 pecially tissue-resident memory in the lung, long-lived bone marrow Ab-secreting cells, and influenza

42 imply a function of stochastically arranged, long-lived but dormant epithelial clonal stem cells muta

43 ared a common developmental lineage and were long-lived but resided in two distinct niches.

44 Immunity to influenza viruses can be long-lived, but reinfections with antigenically distinct

45 ive in the context of generating distant and long-lived C(60)(*-)-ZnP-Fc(*+) charge-separated states.

46 e metabolic output is significantly lower in long-lived C. elegans daf-2 mutants.

47 It stimulated effector generation, long-lived CD4 memory generation, and robust generation

48 interactions between motile immune cells to long-lived cell-cell contacts in epithelia.

49 How long-lived cells deal with ageing-related damage is poor

50 Similar dysfunction in other excitable and long-lived cells including neurons is associated with ne

51 Long-lived cells such as terminally differentiated postm

52 The virus hides in the genomes of long-lived cells, such as resting CD4(+) T cells and dif

53 ters following cART initiation, infection of long-lived cellular subsets and establishment of viral l

54 lones are detected at low frequencies in the long-lived central memory compartment and overrepresente

55 -4 internal tide as an explanation for their long-lived character.

56 nm red-shift in their UV/Vis absorption and long-lived charge carriers (electrons and holes) at room

57 ophysical properties with a high fraction of long-lived charge carriers and the availability of a red

58 phenol to the pyridine, forming a relatively long-lived charge separated state (CSS).

59 ye-sensitized conductive oxides also promote long-lived charge separation with bias dependent kinetic

60 Long-lived charge-transfer excited states that undergo r

61 These long-lived charges are of particular interest for optoel

62 We illustrate how long-lived clonal organisms capture changing mutagenic e

63 ete location of the superior TM and generate long-lived clones and committed progenitors (CPs).

64 receptors reflects receptor accumulation in long-lived closed (desensitized) states, suggesting that

65 These events are part of a long-lived cluster of historical earthquakes along the E

66 no fuel penalty, thereby avoiding additional long-lived CO(2) emissions, would reduce contrail EF by

67 , the weight of these in-gap states displays long-lived coherent THz oscillations up to 2 ps at low t

68 sion hypothesis that pairs of molecules form long-lived collision complexes.

69 spin-orbit coupling, or when strongly bound long-lived complexes are formed that increase the chance

70 nct carrier lifetimes of 0.6 and 31 ps and a long-lived component of several ns.

71 berlites and ocean island basalts contains a long-lived component that formed by melt extraction from

72 an margin is the plate-tectonic paradigm for long-lived, continuous subduction, yet its geology since

73 nstrate time-gated CPL acquisition, enabling long-lived CPL luminescence to be distinguished from sho

74 deally, because muscle tissues are extremely long-lived, CRISPR technology could offer a one-time tre

75 The long-lived CSS and the inverted region behavior associat

76 The purported long-lived Cu(B)(+)-CO complex did not prevent O-O bond

77 different genetic backgrounds, including the long-lived daf-2/insulin like growth factor (IGF) recept

78 that green mEos4b efficiently switches to a long-lived dark state through cis-trans isomerization of

79 We also compare the long-lived dark states reached from green and red mEos4b

80 Long-lived dark states, in which an experimentally acces

81 ayer transition metal dichalcogenides host a long-lived "dark" exciton, an electron-hole pair in a sp

82 racy suppresses chemical reactions, making a long-lived degenerate gas of polar molecules a reality.

83 The role of long-lived dipole-bound resonances built on the singlet

84 We found that long-lived DNA interaction by DNA polymerase are more ab

85 age-dependent changes in the metabolomes of long-lived Drosophila melanogaster.

86 memory phase and that these T cells (termed long-lived effector cells [LLEC]) display robust protect

87 on by the scavenger, but is rather caused by long-lived electron accumulation in (NCN)CN(x) after hol

88 mation of the electron gas, and periodic and long-lived electron cyclotron oscillations inside the ma

89 Designing new quantum materials with long-lived electron spin states urgently requires a gene

90 as high-performance photosensitizers demands long-lived electronically excited metal-to-ligand charge

91 we demonstrate results from higher yields of long-lived electrons due to more efficient reductive que

92 rd and show that the predominant location of long-lived electrons gradually shifts to the F8BT polyme

93 In contrast, long-lived electrons in F8BT already reside on Pd cluste

94 While a low yield of long-lived electrons limits the hydrogen evolution activ

95 , and despite the higher performance of P10, long-lived electrons reside on the P10 polymer rather th

96 nated near simple PSDs, whereas a subset was long-lived, elongated, and associated with complex PSDs.

97 the possibility to discriminate between the long-lived emission of the LT-encoded capture and carrie

98 will be a valuable tool for studies of weak, long-lived emission sources.

99 PL) is one of the most promising methods for long-lived-emission applications.

100 t landscape-scale population collapse of the long-lived, endemic Tasmanian conifer Athrotaxis selagin

101 s system, these results pave the way towards long-lived engineered entanglement on an optical-clock t

102 Many atmospheric organic compounds are long-lived enough to be transported from their sources t

103 aging landscape, we genetically engineered a long-lived equilibrium state characterized by an extende

104 This complex was found to have a long-lived excited state (tau = 4 ns), which was computa

105 n is a unimolecular process occurring on the long-lived excited state of the Ni(II) complex.

106 electron-phonon relaxation and molecule-like long-lived excited states.

107 l theory calculations, first insights into a long-lived excitonic state are gained and discussed.

108 This conclusion suggests that, in long-lived fish species with late sexual maturity and hi

109 evels of tyrosine were increased with age in long-lived flies.

110 For mammals exceptionally long-lived for their body size, we find increased constr

111 of this phenomenon is challenging for vast, long-lived forest ecosystems.

112 gin to understand phenotypic plasticity of a long-lived freshwater fish in response to environmental

113 hich, at intermediate times, bifurcates to a long-lived, fully formed [n]-rung ladder and a pair of s

114 ous oxide (N(2)O), like carbon dioxide, is a long-lived greenhouse gas that accumulates in the atmosp

115 e substantial decreases in emission rates of long-lived greenhouse gasses (GHG).

116 Cells lacking Rpl22Ap, which are long-lived, have lower levels of metabolites associated

117 molecular-weight species usually do not form long-lived high-molecular-weight atmospheres; instead, t

118 timates of mortality and migration rates for long-lived, highly migratory species such as Atlantic bl

119 IMPORTANCE Uncovering the sanctuaries of the long-lived HIV-1 reservoir is crucial to develop cure st

120 insight into the host-parasite dynamics of a long-lived host; determining host-specific associations

121 short-lived model systems, how they apply to long-lived hosts is comparatively understudied.

122 ches cannot efficiently generate multipotent long-lived HSPCs.

123 B cells (GCBCs) are critical for generating long-lived humoral immunity.

124 Memory B cells (MBCs) are essential for long-lived humoral immunity.

125 om RNApII to allow disassembly of abnormally long-lived (i.e., stalled) elongation complexes.

126 te that childhood VZV vaccination can elicit long-lived immune memory responses in the bone marrow.IM

127 pansion method licenses Th17 cells to confer long-lived immunity against solid malignancies via induc

128 ggest that childhood VZV vaccination induces long-lived immunity.

129 covalently closed circular DNA (cccDNA), is long lived in infected hepatocytes.

130 dies suggesting the dystrophin protein to be long-lived in striated muscles in vivo; however, more ri

131 h this mechanism as a new way for generating long-lived in-medium magnetic field in heavy ion collisi

132 Using 2 cohorts of long-lived individuals born in 1905 and 1915 in Denmark,

133 aging rate differences over the lifetime of long-lived individuals in a controlled environment.

134 imated, including the lifespans of short and long-lived infected cells, and the time to reach viral s

135 ng biotrophic growth ultimately allowing for long-lived infection of its perennial hosts.

136 e lymphoid cells (ILC2) are tissue-resident, long-lived innate effector cells implicated in allergy a

137 t accumulation of circRNAs is slowed down in long-lived insulin mutant flies.

138 icularly in the brain and muscle, of diverse long-lived insulin mutants.

139 s potential could be further exploited using long-lived isotopes.

140 for the European badger (Meles meles L.), a long-lived, iteroparous, polygynandrous mammal that exhi

141 In this long-lived Japanese population, mosaic chromosomal alter

142 n a fraction of a second and propagated into long-lived kinetically trapped states (>=90-mer).

143 e between L-Tym and the aptamer, producing a long-lived L-Tym-aptamer complex that blocks hybridizati

144 und viremia in infected individuals due to a long-lived latent reservoir of integrated proviruses.

145 Long-lived leaves with lower maximum photosynthetic capa

146 The theory predicts a long-lived Levy flight regime(11) of the loopy tracer mo

147 supporting relaxation protected states with long-lived lifetimes.

148 r that many strategies can be used to become long lived, likely as a result of variable genome-enviro

149 ted amyloid-like fibrils is shown to provoke long-lived liquid droplets of cytosolic TDP-43 whose ass

150 dinally sampled free-living individuals of a long-lived, long-distance migrant, the Brent goose Brant

151 A key long-lived loop conformation coincides with the opening

152 The spectrally narrow, long-lived luminescence of lanthanide ions makes optical

153 ifferentiation of short-lived monocytes into long-lived macrophages, which is essential for viral dis

154 A long-lived, macroscopic shape deformation is realized in

155 ernal age on fitness across generations in a long-lived mammal.

156 fe-history trajectories and performance in a long-lived mammal.

157 Because bottlenose dolphins are long-lived mammals that develop comorbidities of aging s

158 creased evolutionary constraint in large and long-lived mammals.

159 TMTs are dynamic in length, but are long lived (median >60 min).

160 How long-lived memories withstand molecular turnover is a fu

161 a virus exposures in childhood can establish long-lived memory B cell responses that can be recalled

162 Importantly, vaccination can induce long-lived memory B cells at frequencies comparable to t

163 enter response to ensure latent infection of long-lived memory B cells.

164 tive strategy targeting the proliferation of long-lived memory CD4(+) T cells to reduce viral reservo

165 rapy (ART) as an integrated silent genome in long-lived memory CD4(+) T cells.

166 y production in tandem with the induction of long-lived memory cells for effective recall immunity.

167 learance of the virus, a small population of long-lived memory cells persists.

168 inhibitory receptors and differentiated into long-lived memory cells.

169 characteristics of both early effectors and long-lived memory cells.

170 Short- and long-lived memory could be selectively induced by differ

171 luding clonal expansion and establishment of long-lived memory following infection.

172 ) phenotype are considered precursors to the long-lived memory pool, whereas KLRG1(+)CD127(low) cells

173 r early apoptosis, the remainders comprise a long-lived memory subset, with transcriptional, metaboli

174 and failed to generate memory precursors and long-lived memory T cells.

175 Long-lived memory was mediated by PKA-regulated stress-r

176 Here we report the observation of a long-lived metastable electronic state in an HCI by meas

177 ransferase (alphaTAT), which both stabilizes long-lived microtubules against mechanical stress via ac

178 es not substantially impact the stability of long-lived microtubules.

179 a posttranslational modification enriched on long-lived microtubules.

180 e is known on the time required for immature long-lived migrants to progressively acquire adult-like

181 ence results from the formation of flexible, long-lived molecular cages in the bio-polymer matrix of

182 short-lived low-abundance ES relative to the long-lived more abundant ground state (GS).

183 To investigate the long-lived nature of these cells, we established a DNA m

184 molecular-dynamics simulations both reveal a long-lived network structure that is locally anisotropic

185 by (31)P NMR spectroscopy; (3) there are no long-lived nitroarene partial-reduction intermediates ob

186 stabilized at low levels during the aging of long-lived NMRs and bats.

187 Long-lived normal FOB cells became short lived upon ecto

188 Long-lived ocean island volcanoes are crosscut by thousa

189 tting of the collective spin resonance and a long-lived offset of the Faraday signal are hallmarks of

190 eless designs, these polymers enable stable, long-lived operation as distal stimulators in a rat mode

191 state point defect spins are known for being long-lived optically accessible quantum memories.

192 lizing renewable electricity storage through long-lived organic flow batteries.

193 notypic plasticity in life history traits of long-lived organisms can be difficult owing to high surv

194 The current consensus is that these long-lived oscillatory features likely result from elect

195 on of circulating blood monocytic cells with long-lived osteoclast syncytia.

196 TPM exposure to air resulted in long-lived oxygen centered, secondary radicals with EPR

197 second closed-channel state identical to the long-lived P(480) state, which has been previously assig

198 Specifically, large proteins often fold via long-lived partially folded intermediates, whose structu

199 netic perspective on migratory strategy of a long-lived pelagic seabird: Timings and destinations cha

200 of nucleotide and functional variation in a long-lived perennial plant.

201 teristic old-growth grassland species (e.g., long-lived perennials).

202 on lines, as well as somatic epimutations in long-lived perennials.

203 an ecoevolutionary context, particularly in long-lived perennials.

204 As a result, counterintuitively, the long-lived photoconductivity signal is higher in chemica

205 ich is observed by the formation of a unique long-lived photoproduct as a function of the different d

206 ng, is a widespread reproductive strategy in long-lived plants.

207 4(+) and CD8(+) T cell responses, as well as long-lived plasma and memory B cell responses.

208 e for stability of the bone marrow-resident, long-lived plasma cell population, yet absence of this k

209 port the durability of the memory B cell and long-lived plasma cell populations are not fully elucida

210 antibody, neutralizing antibody, memory and long-lived plasma cell responses compared to conventiona

211 limiting the generation of memory B cell and long-lived plasma cell responses.

212 ensed vaccines confer protection by inducing long-lived plasma cells (LLPCs) and memory B cells (MBCs

213 the lymph node that generate high-affinity, long-lived plasma cells (LLPCs).

214 ss by which antigen drives the generation of long-lived plasma cells and memory B cells and highlight

215 cular processes that drive the production of long-lived plasma cells and memory B cells are subjects

216 by two main B cell memory 'walls' - namely, long-lived plasma cells and memory B cells.

217 Long-lived plasma cells are implicated in the pathogenes

218 lative contributions of germinal centres and long-lived plasma cells as sources of autoantibodies, di

219 pment of antigen-specific memory B cells and long-lived plasma cells that encode TcdB-neutralizing an

220 sponses and may promote the establishment of long-lived plasma cells that secrete antigen-specific, h

221 Significant depletion of long-lived plasma cells, reduction of interferon type I

222 somatically mutated memory B cells (MBC) and long-lived plasma cells.

223 in the expansion of durable bnAb memory and long-lived plasma cells.

224 e seen in many patients, probably related to long-lived plasma cells.

225 r optimal IgG production and accumulation of long-lived plasma cells.

226 ntual differentiation into memory B cells or long-lived plasma cells.

227 hepatic immunotherapy, revealing remarkably long-lived populations of KCs and TRM in human liver, wh

228 conservation outcomes of MPAs for mobile and long-lived predators such as sharks are highly variable.

229 specialized T cell subset that regulates the long-lived production of highly specific Abs by B cells

230 l memory of past antigen exposure can confer long-lived protection against infections or tumors.

231 e humoral immune response provides specific, long-lived protection against invading pathogens, via im

232 pt adjuvant system CAF01 capable of inducing long-lived protection.

233 is representative of most Covid-19 patients, long-lived protective immunity against SARS-CoV-2 after

234 regulation is not a prerequisite to become a long-lived protective memory T cell.

235 arkedly increased proteasomal degradation of long-lived proteins (the bulk of cell proteins) without

236 e proteasome, suggesting that stably folded, long-lived proteins could evade monitoring.

237 Notably, the long-lived proteins that had large (14)N/(15)N ratios we

238 Long-lived proteins, in postmitotic cells, are particula

239 stituents of the eye lens, are prototypes of long-lived proteins.

240 tion increases the turnover of intrinsically long-lived provirus-containing CD4(+) T cells.

241 a backup in the magma plumbing system at the long-lived Pu'u 'O'o eruption site caused widespread pre

242 Detecting either of the long-lived radioisotopes [Formula: see text] or [Formula

243 Strontium-90 ((90)Sr) is the major long-lived radionuclide derived from the Chernobyl accid

244 validated the method in a pig model for the long-lived radiotracer (18)F-Flurpiridaz with adenosine

245 gents and protonation of FAD(*-) to form the long-lived, red-light absorbing FADH(*) species.

246 pressing issue since it forms a visible and long-lived reminder of the environmental impact of consu

247 re HIV-1 infection due to the existence of a long-lived reservoir of latently infected cells.

248 rs, suggesting that greater competition with long-lived resprouters restricts seeder recruitment and

249 Persistent HIV infection of long-lived resting CD4 T cells, despite antiretroviral t

250 ermine the cryoEM structure of the naturally long-lived ribosome complex with eIF5B and Met-tRNA(i)(M

251 Long-lived room temperature phosphorescence from organic

252 H(2)O(2) stimulated the generation of other long-lived ROS in a dose-dependent manner.

253 ow the background value, thereby realizing a long-lived sample of polar molecules in large electric f

254 elated patterns of spatial distribution in a long-lived seabird species during the annual cycle.

255 population of Posidonia oceanica, an endemic long-lived seagrass in the Mediterranean Sea, for genes

256 esident (TR) alveolar macrophages (APhi) are long-lived, self-renew and critical to the health impact

257 B-1a cells are long-lived, self-renewing innate-like B cells that predo

258 We observed a near-periodic, long-lived sequence of more than one million DLPs in the

259 Other long-lived, sessile organisms such as corals appear to b

260 ained from nanopore analysis at pH 6.5 shows long-lived shallow blockades with a mean lifetime of 25

261 scopy (TAS) provide consistent evidence that long-lived shallow-trapped electrons that exist at about

262 ever, unprecedented satellite images showing long-lived short-scale mode-2 internal waves have now be

263 Second, ungulates are large and long-lived, so why are they occasionally intermediate in

264 In long-lived social species, older individuals can provide

265 about the role of older males as leaders in long-lived social species.

266 sion of fetal genes, partially reprogramming long-lived somatic cells in vivo to a primitive, fetal-l

267 This species is a long-lived songbird with early life increases, followed

268 Long-lived species are more likely to have large, non-do

269 f survival similar to familiar pairs because long-lived species avoid jeopardizing survival since the

270 A long-lived species forms and can be assigned as the cati

271 iated role in driving migratory movements of long-lived species in marine systems, and suggest that t

272 In long-lived species in particular, understanding the last

273 ecific genetic changes have been observed in long-lived species including the naked mole-rat, bats, a

274 ns on increased reproductive allocation in a long-lived species of goose, with a particular emphasis

275 These findings suggest that long-lived species start by exploring potentially suitab

276 long-term datasets available, especially for long-lived species such as marine mammals.

277 Long-lived species with delayed maturation, long generat

278 In humans and other long-lived species, harsh conditions in early life often

279 In very long-lived species, such as anthropoid primates, where l

280 empirical support to the hypothesis that in long-lived species, the refinement of migratory behaviou

281 gandong as the last known occurrence of this long-lived species.

282 on in DSB repair efficacy between short- and long-lived species.

283 of early-life adversity in baboons and other long-lived species.

284 s photoexcited spin states in QDs to produce long-lived spin polarization on an appended organic liga

285 Long-lived spinules often contained PSD fragments, conta

286 ed initially upon excitation but decays to a long-lived state that is (3)d-d rather than (3)MLCT in c

287 rovide a blueprint for identifying naturally long-lived states in a decaying quantum system.

288 ildren living with malaria are not similarly long-lived, suggesting a dysfunction in the maintenance

289 cally stable", suggesting it is sufficiently long-lived to diffuse into the enzyme active site for st

290 Our research also reveals a remarkably long-lived tradition of deposition and possible curation

291 This molecule has an exceptionally long-lived triplet LMCT excited state (tau = 350 mus), f

292 ry triplet quantum yield (Phi(T) =52 %), and long-lived triplet state (tau(T) =492 mus), leading to u

293 ception when comparing the life histories of long-lived tropical ectotherms: the seemingly incongruen

294 led us to specifically study a population of long-lived tumor cells enriched in CSCs, which show stem

295 checkpoint', may promote the development of long-lived tumor-specific T(mem) that are essential for

296 of histones revealed specific enrichment of long-lived variants at silent gene loci.

297 cription factors differentially modulated in long-lived versus parental strains indicates a possible

298 edifices, and the evolution and stability of long-lived volcanic systems.

299 o safety assessment of radioactive and other long-lived wastes.

300 g genomic H3K9me2 that is inherited by their long-lived wild-type descendants at a subset of loci.