ライフサイエンスコーパス: long-term administration

1 and is well tolerated by patients even after long term administration.

2 ne is hepatotoxic and unsuitable for chronic long-term administration.

3 and no new adverse events were observed with long-term administration.

4 t efficacy and toxicity concerns surrounding long-term administration.

5 ly deliverable, effective Xe formulation for long-term administration.

6 tized HLA-HCD4/DQ8 mice after short-term and long-term administration.

7 s high doses of drugs that are too toxic for long-term administration.

8 significant hypocholesterolemic effect after long-term administration.

9 ts short in vivo half-life is an obstacle to long-term administration.

10 were mainly of low grade and compatible with long-term administration.

11 ting FXR due to side effects associated with long-term administration.

12 fects and potential noncompliance with their long-term administration?

13 d early recovery of liver mass, whereas more long-term administration (5-7 days) markedly impaired li

14 When PGI2 became available for long-term administration, all nonresponders, as well as

15 Concerns of long-term administration and toxicity exist.

16 nction; however, sustained efficacy requires long-term administration, and some patients fail to tole

17 its of the combined use of these agents with long-term administration are not well defined.

18 However, their long-term administration can lead to potentially serious

19 Its long-term administration can modify the course of decomp

20 throughout the day, however, decreased with long-term administration (decrease in FEV1 from morning

21 ron microscopy to investigate the effects of long-term administration (from 3 to 9 months of age for

22 DSM 33864 in human fecal samples, short-, or long-term administration in mice.

23 class therapeutic to evaluate the benefit of long-term administration in this patient population.

24 roved MTAs have been poorly tolerated during long-term administration, leading to postmarketing dose

25 ncrease contractility in the short-term, but long-term administration leads to an increase in mortali

26 Long term administration of leptin decreases caloric int

27 Long-term administration of 1400W reduced lung inflammat

28 ly bind to endogenous acyl-ghrelin; however, long-term administration of 33A did not affect food inta

29 the brains of Fisher 344 rats induced by the long-term administration of a diet lacking of essential

30 These results show that the long-term administration of a high pharmacological dose

31 aracterize its specific mechanism of action, long-term administration of ABX464 should be studied in

32 The long-term administration of ACE inhibitors to selected p

33 Our results demonstrate that the long-term administration of alpha-lipoic acid has benefi

34 Long-term administration of anti-JAM-C antibodies preven

35 epression or who commit suicide, and because long-term administration of antidepressant drugs to rats

36 r coccidioidal tenosynovitis should focus on long-term administration of antifungal agents.

37 We tested whether long-term administration of antioxidant vitamins C and E

38 Thus, long-term administration of antioxidants can inhibit the

39 ide a good model for study of the effects of long-term administration of ARD on at least one type of

40 Long-term administration of aspirin caused a significant

41 opreventive effect that seems to result from long-term administration of aspirin in vivo.

42 Long-term administration of aspirin leads to reduced dis

43 a new PCI procedure for ISR may benefit from long-term administration of aspirin plus clopidogrel.

44 However, the safe and long-term administration of BACE1-inhibitors as envision

45 drug and route, approaches to titration and long-term administration of baseline and supplemental do

46 Long-term administration of beta-adrenergic blockers to

47 We find that long-term administration of bisphosphonates results in a

48 bortezomib-based treatment, suggesting that long-term administration of bortezomib should be recomme

49 Long-term administration of both estradiol and testoster

50 t the CVAP is a safe and effective route for long-term administration of chemotherapy with an overall

51 Long-term administration of clopidogrel is necessary to

52 ity and other adverse events associated with long-term administration of CNIs.

53 Long-term administration of CTLA4Ig prevents the onset o

54 In this work we investigated the effects of long-term administration of deuterium-enriched vitamin A

55 n this study, we sought to determine whether long-term administration of donepezil would slow amyloid

56 ndent chronic cardiotoxicity attributable to long-term administration of DOX is a significant clinica

57 Identification of ADRs associated with long-term administration of drugs for chronic diseases a

58 ed on complete hardware removal coupled with long-term administration of effective and safe antimicro

59 Long-term administration of eHsp70 significantly enhance

60 In a first analysis, the long-term administration of ENR (100 days) to laying hen

61 odel should provide a good model to evaluate long-term administration of enzyme replacement.

62 Long-term administration of estradiol by injections (EB:

63 rane organelles were assessed in response to long-term administration of ethanol in vivo or acetaldeh

64 However, long-term administration of FTY720 potentially increases

65 Long-term administration of ghrelin to wild-type mice fa

66 Long-term administration of growth hormone to children w

67 goal of this study was to establish whether long-term administration of high dietary glucose rescues

68 These findings indicate that long-term administration of high-dose imatinib mesylate

69 Long-term administration of hydralazine normalized blood

70 acy of imatinib persisted over time and that long-term administration of imatinib was not associated

71 dification is typically achieved through the long-term administration of immunosuppressive drugs.

72 s that enable referring physicians to manage long-term administration of immunosuppressive medication

73 In patients with PAD, long-term administration of L-arginine does not increase

74 As opposed to its short-term administration, long-term administration of L-arginine is not useful in

75 We aimed to determine the effects of long-term administration of L-arginine on vascular react

76 ct health outcomes and cost effectiveness of long-term administration of LAAB-PrEP against COVID-19 i

77 Safety data indicate that long-term administration of larotrectinib is feasible.

78 Rs in striatal neurons which is sensitive to long-term administration of levodopa in PD rats.

79 Long-term administration of low-dose AICAR significantly

80 cted findings for the efficacy and safety of long-term administration of low-dose plerixafor treatmen

81 Long-term administration of mifepristone was well tolera

82 Long-term administration of minocycline prevented retina

83 Long-term administration of montelukast provided consist

84 Long-term administration of n3-PUFA have a beneficial ef

85 However, the long-term administration of olanzapine leads to insulin

86 We hypothesized that long-term administration of oral glycoprotein IIb/IIIa a

87 ic mouse model of diffuse Lewy body disease, long-term administration of phenylbutyrate reduces alpha

88 However, long-term administration of prednisolone can promote myo

89 In conclusion, long-term administration of rhRLX improves renal functio

90 We assessed the long-term administration of romiplostim in splenectomise

91 t exercise-induced asthma is maintained with long-term administration of salmeterol, but the length o

92 With long-term administration of salmeterol, the extent of pr

93 was shown in the estimated lumen volume with long-term administration of SB 217242 (15 mg/kg BID p.o.

94 Long-term administration of sorafenib therapy in combina

95 This suggests that long-term administration of St John's wort may result in

96 Long-term administration of statin therapy has been show

97 e diabetic db(-)/db(-) mouse, and that early long-term administration of the antioxidant CoQ10 may re

98 Long-term administration of the AREDS antioxidants, the

99 Long-term administration of the mitochondria-targeted an

100 The AEs were associated with the long-term administration of the protein synthesis inhibi

101 We tested the hypothesis that long-term administration of the specific angiotensin II

102 ed trial conducted to evaluate the effect of long-term administration of the vasopressin V2-receptor

103 owever, assessing the efficacy and safety of long-term administration of these agents has been limite

104 associated with the need of high dosage and long-term administration of these autophagy inhibitors a

105 AIDs can cause adverse effects, limiting the long-term administration of these drugs to some patients

106 transplantation would eliminate the need for long-term administration of these nonspecific immunosupp

107 ic liver disease and to assess the safety of long-term administration of this drug to these patients.

108 reatment (early stem cell transplantation vs long-term administration of tyrosine-kinase inhibitors)

109 Use of TIVAPs allows long-term administration of venotoxic compounds, improve

110 ausing nonsense mutations will require their long term administration, the ability of PAA to reduce t