ライフサイエンスコーパス: longstanding

1 One longstanding account is selective neuronal tuning to reg

2 f patients with IgG4-RD are reported to have longstanding allergies, peripheral blood eosinophilia, a

3 ophylactic interventions, the latter being a longstanding ambition of the research and clinical commu

4 phenols under mild reaction conditions is a longstanding and formidable challenge in organic chemist

5 There are longstanding and ongoing controversies about the abiotic

6 tifications and physical interpretations for longstanding and recent experimental observations.

7 es by which this fixation occurs have been a longstanding and significant research focus within the c

8 The community music training was a longstanding and successful program that provides free m

9 an Leuven et al. illuminate how a stable and longstanding animal-microbe mutualism increased its inte

10 Despite longstanding appreciation of gene expression heterogenei

11 The longstanding assumption is that saying more than is nece

12 vidence accumulation process challenges this longstanding assumption.

13 ndings provide a neural mechanism to explain longstanding behavioural observations, including the pre

14 There has been a longstanding belief that vertebrates do not produce chit

15 ly unaffected, d's accommodate ligands) is a longstanding bonding model in actinide chemistry, in whi

16 A longstanding bottleneck in realizing this, is various no

17 A longstanding but unfulfilled goal has been to develop po

18 This diversity highlights a longstanding central question: what controls regioselect

19 reaction (ORR) at the cathode has remained a longstanding challenge and requires the design of nonpla

20 onance (NMR) to nanoscale samples has been a longstanding challenge because of the insensitivity of c

21 idization chain reaction (HCR) overcome this longstanding challenge by operating independently within

22 ays involved in forming a covalent bond is a longstanding challenge for chemistry.

23 into colloidal nanocrystals (NCs) has been a longstanding challenge for nanomaterial research.

24 n and organism level during development is a longstanding challenge in biology, but recent molecular-

25 ctional complexity of organisms evolves is a longstanding challenge in biology.

26 ic lineage among a myriad of candidates is a longstanding challenge in developmental biology and an e

27 existence of numerous competing species is a longstanding challenge in ecology.

28 e selective transformation of C-H bonds is a longstanding challenge in modern chemistry.

29 Extracting light from silicon is a longstanding challenge in modern engineering and physics

30 ap states in semiconductor nanocrystals is a longstanding challenge in nanoscience.

31 symmetric alkylation of acyclic ketones is a longstanding challenge in organic synthesis.

32 A longstanding challenge in quantitative analysis is the r

33 A longstanding challenge in studies of neurodegenerative d

34 Thus, a longstanding challenge in the field of biologically medi

35 To address this longstanding challenge in the PET radiochemistry communi

36 la: see text](110) surface, which presents a longstanding challenge in the surface chemistry of metal

37 Faculty diversity is a longstanding challenge in the US.

38 sponse properties in the thalamus has been a longstanding challenge in visual neuroscience.

39 Collectively, these advances address the longstanding challenge of late-stage cross-coupling of f

40 from the interconnections of its parts is a longstanding challenge that has concerned many scientist

41 There is a longstanding challenge to disperse metal nanoparticles u

42 lectron affinities (EAs) of lanthanides is a longstanding challenge to experimentalists.

43 expensive, and scalable method overcomes the longstanding challenge to produce bulk polymer-metal nan

44 It has been a longstanding challenge to visualize how the intricate th

45 The chemical synthesis of insulin has been a longstanding challenge, mainly because of the notorious

46 ies in public health universities has been a longstanding challenge, which we believe might be addres

47 major terrestrial arthropod radiations is a longstanding challenge.

48 rphous cross-linked polymeric materials is a longstanding challenge.

49 f dense, covalent extended solids has been a longstanding challenge.

50 re intermediate storage may occur has been a longstanding challenge.

51 nthetic CO2-fixing enzyme Rubisco has been a longstanding challenge.

52 f electronically unbiased alkenes has been a longstanding challenge.

53 annas, predicting how vegetation varies is a longstanding challenge.

54 e a scalable platform for overcoming several longstanding challenges in applied nonlinear and quantum

55 g-assisted analytical approaches to overcome longstanding challenges in natural products drug discove

56 Longstanding challenges in resolving this functional dic

57 vity in radical processes remains one of the longstanding challenges.

58 Our results refute the longstanding claim that mastigonemes enhance flagellar t

59 on with radiation therapy (RT), leads to the longstanding clearance of tumor in T- and B-cell lymphom

60 ggressive from indolent prostate cancer is a longstanding clinical problem.

61 diagnosis of primary sclerosing cholangitis, longstanding colitis (>10 years), male sex, and younger

62 r (HAS) and L'Hopital Bon Sauveur (HBS) have longstanding commitments to provide equitable surgical c

63 s with non-valvular atrial fibrillation is a longstanding, common, and unresolved clinical challenge.

64 s thus confirm the hallmark predictions of a longstanding computational model of hippocampal memory p

65 Here, we revisit the longstanding concept that some of the gene products enco

66 rough provides an opportunity to re-evaluate longstanding concepts regarding the cause and natural hi

67 There is a longstanding concern about the accuracy of surrogate con

68 A longstanding concern is that reporter assays are mainly

69 (ZIKV) in Latin America brought to the fore longstanding concerns that forests bordering urban areas

70 portunities for translation realized through longstanding connection with the community; integration

71 r-selected regions, allowing, in addition to longstanding consed capabilities such as assembly editin

72 chnological advances, progress has clarified longstanding controversies in the field.

73 Longstanding controversies such as the timing of surgery

74 mised trials hinder clinical management, and longstanding controversies such as use of antibiotic pro

75 The longstanding controversy on the nature of the hydrogen b

76 Our results resolve a longstanding controversy regarding the origin of the ST5

77 A longstanding conundrum has been how yeast survives witho

78 Here, this longstanding conundrum is resolved by demonstrating 100%

79 Longstanding corneal edema can lead to anterior stromal

80 poisons doxorubicin and etoposide constitute longstanding cornerstones of chemotherapy.

81 um immunoglobulin G (IgG) from patients with longstanding CRPS or healthy volunteers followed by asse

82 naptic facilitation, these results resolve a longstanding debate about a widespread form of short-ter

83 Longstanding debate about the adaptive significance of v

84 tiple tubulin isoforms, and there has been a longstanding debate as to whether the isoforms are redun

85 able isotopes to label ejaculates resolves a longstanding debate by revealing how rodent mating plugs

86 iments, but its origin has been subject of a longstanding debate in geochemical research and pollutan

87 characteristic b2 fragment ion, a subject of longstanding debate in MS-based proteomics.

88 A longstanding debate in the face recognition field concer

89 A longstanding debate in the protein-folding field is whet

90 h metallic nanoslits has been the subject of longstanding debates.

91 uration) and 1.22 (0.83-1.80) for those with longstanding diabetes (> 2 years).

92 Longstanding diabetes might increase the risk of acute r

93 ving regular care (59.7%); complicated, with longstanding diabetes, and receiving regular care (16.4%

94 A longstanding dichotomy in cognitive psychology and neuro

95 epresentational spaces, helping to reconcile longstanding differences between the spatial and episodi

96 Patients with UC with longstanding disease and in remission do not have more I

97 ymptoms in patients with UC in remission and longstanding disease in comparison to control subjects.

98 e prevalence of IBS in patients with UC with longstanding disease is not known.

99 The longstanding dogma is that humans exhibit an acute reduc

100 The longstanding dogma that cholesterol (chol) autoxidation

101 This segregation shows Latin America's longstanding economic and social inequality, cemented by

102 Longstanding efforts to develop novel KRAS inhibitors ha

103 Yet despite longstanding efforts to promote equitability and scienti

104 Its emergence complements the longstanding EJ scholarship on later phases of the oil a

105 igures of severe asthma are lacking, whereas longstanding estimates vary between 5% and 10% of all as

106 or inadequate legal demands, and to reassess longstanding ethical certainties in the strictest view o

107 Despite longstanding evidence suggesting a relation between acti

108 Longstanding evidence supports PKC-stimulated DAT traffi

109 ion, and we speculate that it derives from a longstanding evolutionary origin.

110 cusing on mate-choice mechanisms may clarify longstanding evolutionary puzzles in sexual selection an

111 Longstanding experimental studies have suggested that th

112 For most topics, a longstanding expert was paired with an excellent contemp

113 bnormal cardiac output" for a patient with a longstanding family history of heart disease, "decreased

114 In response to a longstanding Federal mandate to minimize the role of geo

115 trioles can also arise de novo, and thus the longstanding focus on centriole 'replication' may have l

116 etails of our laboratory's quest to answer a longstanding fundamental question: Could any new approac

117 The study aims to survey longstanding funduscopic and functional outcomes of age-

118 This discovery fills a longstanding gap in our understanding of a major polymer

119 of intense DNA methylation change, ensuring longstanding genome stability.

120 esions representing severe periodontitis and longstanding gingivitis.

121 uble-stranded DNA (dsDNA) regions has been a longstanding goal as evidenced by the emergence of tripl

122 In particular, a longstanding goal has been to understand how the evoluti

123 ber of photons and harness their energy is a longstanding goal in artificial photosynthesis.

124 surement of cell lineage and cell fates is a longstanding goal in biomedicine.

125 A longstanding goal in cellular mechanobiology has been to

126 A longstanding goal in neuroscience has been to image memb

127 A longstanding goal in neuroscience is to understand how s

128 A longstanding goal in science and engineering is to mimic

129 gen peroxide levels as a function of time, a longstanding goal in the field of redox signaling.

130 Markovnikov additions to alkenes have been a longstanding goal of catalysis, and anti-Markovnikov add

131 r structures, has now opened the door to the longstanding goal of precisely controlling molecular int

132 A longstanding goal of regulatory genetics is to understan

133 A longstanding goal of synthetic biology has been the prog

134 g less than 100 kilodaltons (kDa) has been a longstanding goal of the cryo-electron microscopy (cryo-

135 hemical properties of condensed systems is a longstanding goal of theoretical (quantum) chemistry.

136 cally relevant responses against cancer is a longstanding goal.

137 Two longstanding goals in subsurface science are to induce f

138 e that men with lower amygdala volume have a longstanding history of aggression and psychopathic feat

139 A man in his 70s with a longstanding history of genetically confirmed HCM presen

140 We present three cases with a longstanding history of sarcoidosis that have been addit

141 Longstanding HIV infection acquired when the immune syst

142 This study included 185 women (128 with longstanding HIV infection, 88% under antiretroviral the

143 (MHMS) to a nationwide cohort of people with longstanding HIV to characterize and understand the fact

144 rovide manipulative experimental support for longstanding hypotheses in psychology, that genetic vari

145 ent data from mammalian hair cells challenge longstanding hypotheses regarding adaptation mechanisms

146 One longstanding hypothesis argues that sex is beneficial be

147 We test this longstanding hypothesis in a behavioral experiment that

148 gh underlying mechanisms remain unsettled, a longstanding hypothesis proposes that feedback is due to

149 However, the framework retains the longstanding hypothesis that motor activity is engaged o

150 This longstanding hypothesis, however, has received limited e

151 A longstanding idea about syntactic processing is that it

152 rk has provided experimental support of some longstanding ideas about the striatal circuit and has un

153 Induction of longstanding immunologic tolerance is essential for surv

154 c TCRs de novo from a random repertoire is a longstanding immunological question.

155 r whose clinical and imaging findings showed longstanding inactive disease.

156 Despite longstanding infant vaccination programs in low- and mid

157 Three recipients cleared longstanding infection after intervention with ribavirin

158 A longstanding interest and challenge has been to make suc

159 sformation of triclosan has been a matter of longstanding interest due to both its prevalence in the

160 e two simple building blocks, there has been longstanding interest in engineering the incorporation o

161 The American Board of Ophthalmology has a longstanding interest in patient safety, and in 2015, te

162 There is longstanding interest in studying microbial communities

163 Accordingly, there is a longstanding interest in the development of new opioid a

164 very of the default mode network reignited a longstanding interest in the significance of the brain's

165 Although there has been longstanding interest in the structure and specificity o

166 Despite longstanding interest in understanding whether nonlinear

167 nisms of organogenesis, and has thus been of longstanding interest to developmental and stem cell bio

168 Despite this longstanding interest, the neural representations of gen

169 Despite longstanding interest, the neural structures that proces

170 low in Europe and the United States, despite longstanding international recommendations.

171 Our nation's longstanding investment in federally funded cancer resea

172 ain dynamics in ferroic materials has been a longstanding issue because of its relevance to many syst

173 We resolve this longstanding issue by first determining the scaling of e

174 cisions, rather than interpreting them, is a longstanding issue in plant development.

175 The longstanding issue of the origin of the negative Hall co

176 cancer evolution process and sheds light on longstanding issues regarding the origins of molecular s

177 ith HIV viral suppression and more advanced, longstanding liver disease is associated with changes in

178 host-pathogen interactions, and has answered longstanding mechanistic questions.

179 he peripheral benzodiazepine receptor, is of longstanding medical interest as both a biomarker for ne

180 PARTICIPANT: A 49-year-old man with longstanding, medication-resistant, upbeat nystagmus res

181 an Ciona consists of only 40 cells, and is a longstanding model for studying organogenesis in a small

182 A longstanding model is that activated Bak and Bax insert

183 These results provide empirical support for longstanding models of sex chromosome catalysis, and sug

184 provides an alternative explanation for this longstanding mystery about generation of concurrent soun

185 Cloning the sigma2 receptor resolves a longstanding mystery and will enable therapeutic targeti

186 ovide will accelerate our understanding of a longstanding mystery in EBV biology and guide efforts to

187 ismatch imparted by the dodecameric portal-a longstanding mystery in icosahedral viruses-and inform p

188 alling and response in laticifers resolves a longstanding mystery of ethylene stimulation in rubber p

189 shaping horticultural traits, and resolve a longstanding mystery of the regaled golden poppy.

190 enation but whose molecular basis has been a longstanding mystery.

191 There is, however, a longstanding need for a reliable form of secondary imagi

192 tor (VEGF) therapy, indicating a more mature longstanding neovascular complex resistant to anti-VEGF

193 s poor psychosocial outcome is the result of longstanding neurological changes, whereas for others it

194 The data presented here challenge this longstanding notion and argue instead for segregated ope

195 neuroimaging findings have greatly modified longstanding notions regarding the pathophysiology of am

196 expanded tolerability, thereby addressing a longstanding objective for many clinical applications.

197 ct targeting of KRAS oncoproteins has been a longstanding objective in precision oncology.

198 findings also suggest an explanation for the longstanding observation that M. tuberculosis initiates

199 properties of VWF helps us to understand the longstanding observations concerning the bleeding compli

200 depolarization of these solid solutions is a longstanding obstacle for their practical applications.

201 exity evolves in biological populations is a longstanding open question.

202 ME seems to be a common complication of longstanding OT in the adult.

203 This work helps to refine a longstanding paradigm indicating stress granules are ine

204 One longstanding paradigm involves the growth of a relativel

205 This longstanding paradigm is being challenged by two papers

206 Our findings question the longstanding paradigm that alphaherpesviruses can establ

207 expression in GC progression, challenge this longstanding paradigm.

208 We apply this theory to explain a longstanding paradox in biology and medicine: the evolut

209 election may provide an explanation for this longstanding paradox of population genetics.

210 e and decreased intracranial volume (ICV) in longstanding patients.

211 Longstanding persistent (LSP) atrial fibrillation (AF) i

212 AF (OR, 1.01; 95% CI, 0.63-1.64; P=0.96) or longstanding persistent AF (OR, 0.84; 95% CI, 0.24-2.96;

213 Patients with persistent/longstanding persistent AF and LVEF <=35% were randomly

214 edure Outcome in Patients With Persistent or Longstanding Persistent Atrial Fibrillation Undergoing C

215 th AF (paroxysmal: n=3; persistent: n=4; and longstanding persistent: n=3) and 4 patients without a h

216 However, there is a longstanding perspective, and ample functional magnetic

217 presence of PEG-specific antibodies may be a longstanding phenomenon.

218 Reusing wastewater for irrigation is a longstanding practice that enhances crop yields and impr

219 Overlapping surgery is a longstanding practice that has not been well studied.

220 rolling chemical reactivity using light is a longstanding practice within organic chemistry, yet litt

221 determines the length of S phase has been a longstanding problem in developmental biology.

222 A longstanding problem in the social, biological, and comp

223 r differential perturbations may address the longstanding problem of discriminating direct and indire

224 al weather records can be used to tackle the longstanding problem of predicting cultivars' future per

225 findings provide important insights into the longstanding problem of the position of the root of the

226 This method, which addresses a longstanding problem, is useful for assessing how geneti

227 This is consistent with the longstanding proposal that condensin provides a bias in

228 nation rate declines as patients progress to longstanding PsAF, underscoring the importance of early

229 tropin-releasing hormone (GnRH) represents a longstanding puzzle about extracellular signal decoding

230 Herein, we resolved this longstanding puzzle by combining a detailed product anal

231 gin in Waldenstrom macroglobulinemia (WM), a longstanding puzzle due to conflicting and incomplete da

232 It is a longstanding puzzle why non-coding variants in the compl

233 ir widely varying accretion rates-has been a longstanding puzzle.

234 utes to early auditory processing has been a longstanding puzzle.

235 t during enzymatic turnover, thereby solving longstanding puzzles.

236 X inactivation presents two longstanding puzzles: the counting and choice of X chrom

237 The results clarify a longstanding question about the mechanism of cathepsin A

238 Here, we answer this longstanding question by using transgenic Hydra expressi

239 A longstanding question concerns the structure of the C-te

240 A longstanding question in cellular neuroscience is how mi

241 A longstanding question in sensory neuroscience is what ty

242 ogether, the results of this study address a longstanding question in the field and suggest that acti

243 fection or reactivation of latent virus is a longstanding question in the field.

244 A longstanding question in this field is how the function

245 A longstanding question is how influenza virus evolves to

246 A longstanding question is how Ptc inhibits Smo and how su

247 A longstanding question is how the cell builds and maintai

248 chanism provides important insights into the longstanding question of how the receptor transduces sig

249 at stress to whole seedlings, we address the longstanding question of possible heterogeneity among ce

250 e sGC heme domain reported here resolves the longstanding question of where stimulators bind and prov

251 al equivalent of nsp1, thereby answering the longstanding question of whether lack of nsp1 in gammaco

252 a formation, thus providing insight into the longstanding question of why nerves are required for axo

253 In doing so, we also address a longstanding question regarding what factors are at our

254 A longstanding question regards the evolutionary pressures

255 t motivates animal cells to intercalate is a longstanding question that is fundamental to morphogenes

256 Here, we resolve this longstanding question using a mouse model null for the g

257 tely despite stochastic neural activity is a longstanding question(1).

258 sian monsoon on varying timescales remains a longstanding question.

259 s and give rise to conscious experience is a longstanding question.

260 Many longstanding questions about dynamics of virus-cell inte

261 fant baboons with B. pertussis, are enabling longstanding questions about pertussis pathogenesis to b

262 as compared to that of each EBNA3 to resolve longstanding questions about the EBNA3-polycomb relation

263 To answer longstanding questions about the origin of these complex

264 lize toxic oligomeric complexes could answer longstanding questions about the pathogenesis of other p

265 authorship of Andreas, shedding light on two longstanding questions in Old English philology.

266 The data reported here address several longstanding questions regarding antibody repertoire sel

267 les self-assembled from aqueous surfactants, longstanding questions remain regarding their surface st

268 mates and providing statistical insight into longstanding questions that have previously been address

269 evelops to direct distinct cell fates remain longstanding questions.

270 disease 2019 (COVID-19) pandemic has exposed longstanding racial and ethnic inequities in health risk

271 Longstanding racial disparities in heart failure (HF) ou

272 The use of a thiocarbonyl acceptor overcomes longstanding reactivity problems in the field to give co

273 Longstanding reports of polyspecificity of anti-lipid A

274 Despite longstanding research efforts, our understanding of the

275 A longstanding research goal has been to understand the na

276 ication) tasks to assess awareness overcomes longstanding residual methodological problems, and prior

277 enzyme, RuBisCO, attests to the crucial and longstanding role it has played in the biogeochemical cy

278 during the clinical course of patients with longstanding RP.

279 f the current digital culture coincides with longstanding scientific questions about why humans somet

280 For those with longstanding sequaelae from incomplete recovery, aesthet

281 enchymal transition (EMT) in metastasis is a longstanding source of debate, largely owing to an inabi

282 This approach lowers a longstanding technical hurdle to manipulating large prot

283 olling spin magnetism with electric fields-a longstanding technological goal in spintronics and multi

284 Despite decades of declining crime rates, longstanding tensions between police and the public cont

285 These results yield compelling support for longstanding theoretical predictions by revealing the im

286 erminants of parasite virulence, and reforms longstanding theory on clonality in trypanosomatid paras

287 This finding challenges a longstanding "two-site" hypothesis about the essential f

288 Longstanding type 2 diabetes (T2DM) is a risk factor for

289 e significantly associated with dysplasia in longstanding UC.

290 ssors and four nonprogressors suffering from longstanding UC.

291 A longstanding, unanswered question is whether nuclear org

292 he potential of causal networks to constrain longstanding uncertainties in climate change projections

293 However, longstanding uncertainties in their ability to simulate

294 We conclude that the longstanding use of ecological theory by biocontrol prac

295 se processes represent an alternative to the longstanding use of stoichiometric organometallic reagen

296 Models in widespread and longstanding use that describe these mixtures apply an a

297 Treating cattle with endectocide is a longstanding veterinary practice to reduce the load of e

298 Additionally, our findings challenge the longstanding view that within squamates the Iguania are

299 adiation-aware hydrologic model resolves the longstanding, wide disparity in sensitivity estimates an

300 infinite-length "random" sequences have been longstanding yet incompletely resolved problems.