ライフサイエンスコーパス: loosely

1 number of fused thiophene rings packed more loosely.

2 chastic point process with a given rate, and loosely (2) the variance of the rates that would produce

3 MBP is loosely accommodated in the HLA-DR4-binding groove, acco

4 PGE2 switches pericytes to a fast-migrating, loosely adhered phenotype that fails to intimately inter

5 in the individual fluorescent gel blocks are loosely adhered to one another.

6 rface layer, a meshwork of surface-bound and loosely adherent glycosaminoglycans and proteoglycans, m

7 ly devoid of bacteria, followed by a second, loosely adherent layer that contains numerous bacteria.

8 l-matrix adhesion.In HEK293 cells, which are loosely adherent, expression and stimulation of human or

9 d only when the two-dimensional material was loosely adhering to a substrate.

10 1b appeared as cytoplasmic diffuse granules, loosely aggregated filaments, or compact spheres in p75(

11 ss synapses, whereas the remaining 44% had a loosely anchored ribbon.

12 This suggests that the remaining loosely anchored ribbons in Bsn(gt) IHCs were functional

13 e of unknown function, even when function is loosely and minimally defined as 'belonging to a superfa

14 Unstructured protein or polymer chains pack loosely and readily rearrange, leading to fast fusion.

15 y of fisheries and food security remain only loosely and superficially linked.

16 Previously, we observed a loosely and tightly docked state preceding leaflet merge

17 However, the term "social learning" has been loosely applied to a variety of psychological phenomena,

18 nd analysis of citational material that Livy loosely appropriated from earlier sources.

19 Also, SOD1 myotubes had loosely arranged myosin heavy chain and reduced acetylch

20 /=50%, >50%, or 100% of cells; identified as loosely arranged small myocytes positive to HCN4 immunos

21 ar portion, comprised of the LBD and NTD, is loosely arranged, mediating complex allosteric regulatio

22 ns, including bilaterally separate jaws that loosely articulate with the skull, hyper-expandable thro

23 mplexes extract predominantly in the form of loosely assembled tetramers from purified measles virus

24 -terminal distal three residues disrupts the loosely assembled trimer and favors the formation of a d

25 ross-linked by dynamin2 and cortactin became loosely associated after GTP addition when viewed by tra

26 Motor axons in frac LOF embryos are loosely associated and project ectopically, a phenotype

27 These ions form a loosely associated cloud referred to as an ion atmospher

28 to high ionic strength that would strip more loosely associated integrase from internal regions of th

29 Electrostatic shielding from loosely associated metals is undoubtedly an important in

30 indicate that beta-sheet channels break into loosely associated mobile beta-sheet subunits.

31 aphic structures of hGITRL, which revealed a loosely associated open trimer with a deep cavity at the

32 ntexts cells migrate either individually, as loosely associated sheets or as clusters of cells.

33 H2A.Z in both yeast and human cells are more loosely associated with chromatin than the full-length p

34 rus/enterovirus FA targets revealed patterns loosely associated with EV-D68 that may be useful for co

35 tion analyses revealed that nectar spurs are loosely associated with increased diversification rates.

36 vailable state (labile heme), in which it is loosely associated with proteins, lipids, nucleic acids,

37 SII supercomplex, whereas up to two more are loosely associated with PSII in state 1 in higher plants

38 lular strands and patches of ANME-1 that are loosely associated with SRB cells, but not tightly conne

39 e to abstract a proton from a water molecule loosely associated with the alpha-metal ion.

40 Mne1 is a mitochondrial matrix protein loosely associated with the inner membrane and is found

41 a conversion was incomplete, and Mo was only loosely associated with the NifEN-bound "FeMoco".

42 aused form of RNA polymerase II (Pol II) was loosely associated with the ORF45 promoter region during

43 Plant eIF4A is very loosely associated with the plant cap-binding complexes.

44 VioA forms a "loosely associated" homodimer as indicated by small-angl

45 g to their association status (unassociated, loosely associated, or tightly associated), improving ho

46 velope at their carboxyl termini, and E(rns) loosely associates with the viral envelope.

47 lly cleaved portion of XptC1 apparently only loosely associates with this binary complex.

48 water, in comparison to the more porous and loosely attached biofilms at low flow rates.

49 A loosely attached cell is more compliant under indenting.

50 ls also produced H(2) and ATP from CO (via a loosely attached CO dehydrogenase) or a chemical reducta

51 ulations K3 also forms ion channels with 3-6 loosely attached mobile subunits.

52 ecific complement of functionally important, loosely attached peripheral proteins to that membrane.

53 ere rigidly attached as compared to the more loosely attached QDs.

54 Abeta(17-42) peptides form ion channels with loosely attached subunits and elicit single-channel cond

55 that PG-1 forms channel-like structures with loosely attached subunits when reconstituted in anionic

56 the barrels still break into heterogeneous, loosely attached subunits, in good agreement with AFM im

57 extract the correct Young's modulus of cells loosely attached to a substrate.

58 study mechanics of many other types of cells loosely attached to substrates, e.g., blood cells, some

59 ecies in solution and that two RAIDD-DDs are loosely attached to the 5:5 core.

60 c bones are suspended in a muscular sling or loosely attached to the pectoral girdle anteriorly.

61 do not develop sufficient adhesion, and are loosely attached to the substrate.

62 INF2-non-CAAX is loosely attached to this meshwork, being extracted by br

63 g the second phase (sampled at E38-E45), the loosely banded S-cell distributions were transformed int

64 l diffusion from water molecules that either loosely bind to or exchange protons with the DNA.

65 Our results show that, while the dominating loosely bond signature is attributed to a one-dimensiona

66 nly attributed to its layered structure with loosely bonded N-Mo-N sandwich interlayers held by weak

67 that tends to reorient water molecules more loosely bonded to the topmost water layer with oxygen to

68 M184V):DNA:3TC-TP also demonstrated that the loosely bound 3TC-TP is misaligned at the active site to

69 resent in the natural aquatic environment as loosely bound aggregates or "flocs" and is responsible f

70 shaped ATPase motors, for example the use of loosely bound and tightly bound hydrolysis reactant and

71 lved in ion transport, because such ions are loosely bound and very difficult to detect experimentall

72 mponents that are present individually or in loosely bound assemblies.

73 sly the intimate interconnection between the loosely bound bimolecular intermediate identified concur

74 r the AgNP surface, where nanoparticles with loosely bound capping agents are more effectively stabil

75 nd tightly bound cells than in epiphytic and loosely bound cells.

76 nically excited atom or molecule placed in a loosely bound chemical system (such as a hydrogen-bonded

77 This intermediate resembles a loosely bound complex between an electrophilic nitrosyl

78 fast rearrangement of the complex to form a loosely bound complex.

79 onspecific complexes, and a diffuse cloud of loosely bound complexes connecting the specific and nons

80 s and neural tissue maintain basal stores of loosely bound copper that can be attenuated by chelation

81 mal amount of MBCD to the RC sample captured loosely bound detergent from the protein-detergent compl

82 crystal contacts hypothesized for removal of loosely bound detergent.

83 enically cooling the ion and tagging it with loosely bound deuterium (D2) enabled detection of its vi

84 Because of their loosely bound electrons, electrides offer physical prope

85 ncrease in conductivity is attributed to the loosely bound Fe(2+) beta-spin electron.

86 We find that FtsZ forms bundles made of loosely bound filaments of variable length and curvature

87 abilization based on the results featuring a loosely bound first state, a tightly bound second state,

88 icals in soil, whereas air accesses only the loosely bound fraction, and these two pools are subject

89 ed that DCM removes both the sequestered and loosely bound fractions of chemicals in soil, whereas ai

90 distance between the mRNA entry site and the loosely bound RNA site on the 40S subunit was estimated.

91 lattice, essentially transforming them from loosely bound structures to ones with very strong interp

92 rature processing to strip away all free and loosely bound surfactant, leaving behind concentrated, k

93 excess target and stringent washing removes loosely bound targets.

94 l described by these analyses, but were more loosely bound than the bonds in events 2 and 3.

95 pper also exists in labile pools, defined as loosely bound to low-molecular-weight ligands, which can

96 ealed experimentally, especially if they are loosely bound to macromolecular surface.

97 It is demonstrated that LHCIIs loosely bound to PSII in State I are the trimers mainly

98 We show that truncated SrtA mutants that are loosely bound to the cytoplasmic membrane form high-mole

99 f contact ion pairs with the glycosyl moiety loosely bound to the leaving group, and eventually solve

100 Such loosely bound triple systems will therefore appear to be

101 As in other classes of AC, the ribose is loosely bound, and as in class III, no base appears to i

102 ng data points to the presence of additional loosely bound, labile pools that can participate in dyna

103 n-Cooper-Schrieffer (BCS)-type superfluid of loosely bound, large Cooper pairs to Bose-Einstein conde

104 the active form is favored while a ligand is loosely bound.

105 A novel scaffold composed of loosely branched hollow silica microfibers that has been

106 e Z ring comprises short, discontinuous, and loosely bundled FtsZ polymers, some of which are tethere

107 ally consisting of up to approximately eight loosely but irreversibly assembled monomeric subunits.

108 ection of a few peptide chains held together loosely by hydrophobic interactions into a spherical hyd

109 cells invested tightly by pericytes and more loosely by macrophages.

110 temporally, diverse DENV isolates clustered loosely by type, but we found that many are as similar a

111 oss environments, a phenomenon that has been loosely called 'demographic compensation', may allow spe

112 vaccine- or drug-based interventions can be loosely categorized by the degree to which the infectiou

113 Traditionally, viruses are loosely classed into two groups: slow-evolving DNA virus

114 pe I restriction endonucleases could only be loosely classified as enzymes since they functioned stoi

115 atic analysis shows that ALL populations are loosely clustered and close to the normal population tha

116 merous genomic positions generally serves to loosely coalign homologous chromosomes, while crossover-

117 g of the nucleoprotein to RNA can assemble a loosely coiled NC-like structure; the loose coil can be

118 substitution N(Y415A) or N(K417A) were more loosely coiled, as revealed by electron microscopy (EM).

119 ric relating uniquely to the covariates, and loosely collected species generally prevailed with relat

120 as either sharply delineated communities or loosely collected species have also hampered progress in

121 on assay preferentially detects early-stage, loosely compacted lesions such as pale bodies in patient

122 h most network remodeling occurring within a loosely connected 'accessory' module.

123 We theorize that these levels are loosely connected by multiple constraints and that both

124 r the presence of brain lymphatics and found loosely connected endothelial cells with lymphatic molec

125 from thirty-nine bighorn sheep across seven loosely connected populations in the Mojave Desert and a

126 erhelical termini within each nucleosome are loosely connected to CENP-A, and we identify the key ami

127 results suggest that the CH domain, which is loosely connected to the MO domain by a flexible linker

128 es have been limited to quantities which are loosely connected to the topological properties of these

129 l of TP design is that they contain multiple loosely conserved motifs that are recognized at differen

130 ions rely on parameterizations that are only loosely constrained by present day changes.

131 ion to canonical SUMOs, land plants encode a loosely constrained noncanonical isoform and a variant c

132 : i) excessive CPU time requirements and ii) loosely constrained optimization problem due to lack of

133 The age of weathering, however, remains loosely constrained, which has an impact on existing geo

134 and their associated environmental variables loosely constrains the parameterization of process-based

135 and 8 microM free Ca(2+) contains a single, loosely coordinated metal ion.

136 rs by dialkylammonium cations coupled to the loosely coordinating superweak TFPB(-) anion has been ac

137 ts of individual mutations on ATP hydrolysis loosely correlated with RapA's nucleic acid remodeling a

138 mRNPs are organized into three major domains loosely corresponding to 5' untranslated regions (UTRs),

139 frican Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeaste

140 Na(+) conduction is shown to involve the loosely coupled "knock-on" movement of two solvated ions

141 We achieve this by incorporating many loosely coupled 'particles', which are incapable of inde

142 A loosely coupled allosteric network, comprising three reg

143 PaperBot implements these capabilities as a loosely coupled collection of distinct modules devised t

144 This loosely coupled model can account for the observed physi

145 e propose that the decision is taken by many loosely coupled modules each of which represent a stocha

146 The loosely coupled motor is predicted to be especially adva

147 Under loads relevant to a swimming cell, the loosely coupled motor would perform about as well as a t

148 ce if implemented as a distributed system of loosely coupled parts that interact through clearly defi

149 anodine, consistent with cross-activation of loosely coupled ryanodine receptors.

150 e neurons, we found that exocytosis was more loosely coupled to calcium entry than in fast synapses.

151 de array of hydrologic processes, and may be loosely coupled to climatic processes and therefore buff

152 and I identify many different elements only loosely coupled to each other.

153 he force-generating region of myosin is only loosely coupled to the ATPase reaction, with conformatio

154 r more generally to visualize two nested but loosely coupled trees.

155 ried waters whose exchange with bulk is only loosely coupled with the motion of loops in their vicini

156 L1 stalk closure and subunit ratcheting are loosely coupled, independent processes that must converg

157 rate that the mitochondria in EDL fibres are loosely coupled.

158 Using a network model of loosely-coupled Wilson-Cowan oscillators to simulate a p

159 s arthropods and vertebrates is dependent on loosely cross-linked bundles of microtubules running all

160 rsible iron-catechol cross-links into a dry, loosely cross-linked epoxy network.

161 pread tendency to interpret data in terms of loosely defined 'age regulation', which does not usually

162 ases of the C-superfamily (GT-Cs), which are loosely defined as containing membrane-spanning helices

163 r, their functional role is often unclear or loosely defined as experimental characterization is chal

164 ry reconsolidation depends on a set of still loosely defined boundary conditions, limiting the transl

165 der to help further the field, we close with loosely defined design rules that are at the basis of th

166 asses of effectors in which the signal has a loosely defined motif and others in which secretion is d

167 along surface pili, while RrgC is found in a loosely defined relationship with RrgA.

168 of plasmid DNA within the periphery of this loosely defined, chromosome-containing region.

169 to a high affinity binding site that remains loosely defined.

170 onses to healthcare-associated exposures are loosely defined.

171 arative structural analysis identified three loosely-defined consensus structural motifs for kinase r

172 set of factors, which are divided among two loosely-defined groups, for these functions.

173 li exhibit rudimentary behaviors that can be loosely described in terms of cognitive phenomena such a

174 Spindle and round cells were loosely distributed with increased particles after TP tr

175 adherens junction protein P-cadherin appears loosely distributed within the albino RPE cells rather t

176 es from basal attine genera continue to farm loosely domesticated fungal cultivars capable of pursuin

177 ge cages and singly occupied small cages are loosely encaged and the vibrational modes are softened a

178 bilization of acetonitrile and release of a "loosely" encapsulated solvent molecule during 10a/b inte

179 OS assembly has the dynamical structure of a loosely entangled polymer.

180 ts a beta-hairpin-like conformation with two loosely extended peptide chains, demonstrating the prefe

181 cation and inorganic (or organic) anion that loosely fit together, is extending the properties and cl

182 e incorporation of excess membrane to form a loosely fitting bilayer that can be used to study membra

183 A mask documented to be loosely fitting by a PortaCount fit tester, to simulate

184 ausative agent of anthrax, are enclosed by a loosely fitting exosporium composed of a basal layer and

185 fitted respirator performs no better than a loosely fitting mask.

186 hat offer little information beyond age, and loosely fitting models may contain a lot of noise.

187 the etiological agents of anthrax, possess a loosely fitting outer layer called the exosporium that i

188 n we found that the detached head occupies a loosely fixed position to one side of actin from which i

189 n the target region needs to be isolated but loosely focused when the target region is clearly segmen

190 Primary structure of dematin includes a loosely folded core domain and a compact headpiece domai

191 gh a step that requires ATP hydrolysis and a loosely folded domain on the protein, but appears indepe

192 teasomes, but only if the proteins contain a loosely folded domain.

193 further characterized in the context of the loosely folded isomerized native-like state {N(iso)} pre

194 Unfolded or loosely folded polypeptides can inhibit this tighter bin

195 Thus, ubiquitinated loosely folded proteins, after becoming bound to the 26

196 they bind a ubiquitinated protein, which is loosely folded.

197 Our data reveal that the loosely formed capsid structure is reinforced post-assem

198 me-substrate intermolecular interactions are loosely formed when the substrate is in the reactant and

199 These problems are loosely grouped into challenges concerning nosology and

200 or virus manipulation of RNA granules can be loosely grouped into three nonexclusive categories: (a)

201 nate thalamically and downstates cortically, loosely grouping spindle occurrence.

202 Energetic analysis of tightly and loosely held computed hydration sites indicates protein

203 tween the N- and C-terminal domains that are loosely held together by hydrophobic and hydrogen bond i

204 elative to its N-substituted (and therefore "loosely held") analogue 9, provided compelling experimen

205 ereas weak binding low affinity ligands bind loosely in the active site, resulting in a distribution

206 we introduce an active matter system that is loosely inspired by biology and which we term an active

207 Tightness-looseness is part of a complex, loosely integrated multilevel system that comprises dist

208 rmed by beta-sheets spontaneously break into loosely interacting dynamic units that associate and dis

209 ructures that are highly intraconnected, but loosely interconnected.

210 Mechanistic analyses reveal that loosely ion-paired halide ions in DMA-LiCl are critical

211 thods, we determine that the NBD and SBD are loosely linked and can move in cones of +/-35 degrees wi

212 htly linked colour and banding loci and more loosely linked pigmentation, spread band and punctate lo

213 e ossified Meckel's cartilage; the latter is loosely lodged on the medial rear of the dentary.

214 ient of collateral innervation might help to loosely maintain functional synaptic circuits if functio

215 provide the main driving force for binding, loosely mimicking the binding mode found in the recognit

216 of mineral elements in the planktonic cells loosely mirrors the media composition; however the uniqu

217 Fs in the K562 and GM12878 cell lines, which loosely model the transition between normal and cancerou

218 ich has been several years in the making, is loosely modeled after a key pinacol shift in the propose

219 two separate phases (cyclase and oxidase) as loosely modeled after terpene biosynthesis.

220 m, insect-scale, flapping-wing robot modeled loosely on the morphology of flies.

221 e a model animal, with a neural system based loosely on the rodent hippocampus, which performs mental

222 Based loosely on this sequence, we identified five potential N

223 anges in the C-terminal arm result in a more loosely organized active site and flexible binding modes

224 a basal lamina significantly denser than the loosely organized CNS matrix.

225 remains flexible and adaptive by maintaining loosely organized domains, while its heterodimerization

226 We suggest that the transition state is a loosely organized ensemble of conformations.

227 l- and tissue-based assays usually reside in loosely organized files of poorly documented provenance.

228 in colonic epithelium, often accompanied by loosely organized lamina propria infiltrates.

229 horizontal streak of the Nubian ibex appears loosely organized possibly reflecting a reduced predatio

230 ortical and spinal motor command centers are loosely organized with respect to the musculotopic spati

231 sting databases of plasmids and features are loosely organized.

232 e mutations lead to a group of diseases with loosely overlapping symptoms and pathology.

233 good healing, whereas group 2 aneurysms were loosely packed (volumetric packing density, <20%), which

234 in aquatic environments are associated with loosely packed aggregates of particulate material called

235 izable podosomes, their podosome arrays were loosely packed and improperly localized within the cell.

236 ism in GFP folding forming an incorrectly or loosely packed barrel under intermediate (hysteretic) fo

237 llel, four-helix bundle; and HAMP(B), a more loosely packed bundle with an altered AS2/AS2' packing a

238 Ultrastructural examination revealed loosely packed collagen fibrils with abnormal orientatio

239 After irradiation, there is an increase in loosely packed collagen fibrils, which is significantly

240 nel in a membrane environment suggest a more loosely packed conformation with water-accessible intras

241 Here we report a loosely packed crystal of dendrimeric rotor 2 and the fa

242 the near-surface electric field generated by loosely packed dipoles on mixed F/H-terminated surfaces

243 und reduction of EndoIII on both closely and loosely packed DNA films.

244 For loosely packed DNA monolayers, the conjugation of the po

245 helices at the intracellular end but is more loosely packed from 10' to the extracellular end than th

246 into tightly packed heterochromatin and the loosely packed gene-rich euchromatin regions.

247 rmational extremes of a tightly packed and a loosely packed HAMP four-helix bundle support only low l

248 o individual GFC beta-sheets and a large but loosely packed hydrophobic cluster.

249 ms to be poised toward downhill folding by a loosely packed hydrophobic core with low aromatic conten

250 that K-Ras4B can be distributed in rigid and loosely packed membrane domains.

251 Output helices that are too tightly or too loosely packed most likely produce kinase-off output sta

252 between ellipsoids lead to the formation of loosely packed or arrested structures on the air-water i

253 tion is a complex structural evolution, from loosely packed oxide particles in the green body to full

254 ets is covered by a shell of less-activated, loosely packed platelets.

255 ets is covered by a shell of less-activated, loosely packed platelets.

256 elets overlaid by a shell of less-activated, loosely packed platelets.

257 particle extends previous findings that the loosely packed precursor RNP undergoes a dramatic confor

258 t stimuli, consistent with facile changes in loosely packed receptors.

259 h-like structure comprising porous ZIF-8 and loosely packed rGO nanosheets.

260 of the molecular diodes, and junctions with loosely packed SAMs result in poorly performing molecula

261 dilute fluids of colloidal hard spheres form loosely packed sediments, where the volume fraction of t

262 red lamellar structures for SA compared with loosely packed short lamellar structures in GMS oleogel,

263 higher flexibility of the AHR PAS-A and its loosely packed structural elements, suggest a dynamic st

264 he protein assumed a roughly spherical, very loosely packed structure.

265 mpse of the intron RNP precursor as a large, loosely packed structure.

266 ith significant secondary structure but only loosely packed tertiary structure, has been suggested to

267 usters are lined with residues that are more loosely packed, a structural feature that facilitates mo

268 that, within 3-d colonies, E. coli cells are loosely packed, and colonies produce about 2.5 times as

269 ent in the solid-state when the hydrazone is loosely packed.

270 , fast-diffusing proteins corresponding to a loosely, probably electrostatically bound state; 2), slo

271 ative green/sodium dodecyl sulfate gels, the loosely PSII-bound LHCb was separated from the LHCb that

272 urines in various mammalian tissues has been loosely quantified, the concentration of purines present

273 But we also draw on loosely related events to infer and imagine the outcome

274 ese future-oriented thoughts may be based on loosely related past experiences or unrealistic optimism

275 that they detect sensitization which is only loosely related to clinical allergy.

276 ed on past experiences, including those only loosely related; perceived familiarity with treatment op

277 is possible to engineer charge clusters that loosely resemble catalytic sites in a scaffold protein w

278 ensive overlap in Gr-ligand interactions and loosely separates sweet receptors into two groups matchi

279 The results indicated that Cr(VI) was loosely sorbed as an outer-sphere complex on Mn(IV)O(2),

280 and DegB, a hydrophobic sequence within the loosely structured C-terminal tail of Ndc10.

281 riptional repression by Alu RNA involves two loosely structured domains that are modular, a property

282 idues were in conformational exchange with a loosely structured intermediate with a population of 1-2

283 The p66 monomer exists as a loosely structured molecule in which the fingers/palm/co

284 s process exist throughout the brain and are loosely termed adaptation.

285 e questions that they can address, have been loosely termed evolutionary and ecological functional ge

286 At the barbed end the terminal subunit is loosely tethered by its DNase-1 loop to the third subuni

287 receptor binding protruding (P) domain only loosely tethered to the main capsid shell.

288 ed in a unique phenotype: precursor vesicles loosely tethered to the MOP but did not contact its surf

289 zene complex in which the arene is held more loosely than in the ground state, primarily through disp

290 s all substrates and products, although more loosely than P450 17A1.

291 on at the stem-loop interface is packed more loosely than with Mg(2+), to allow for a lower charge de

292 These separate clusterings adhere loosely to an overall consensus clustering, and hence th

293 12-HSL, and because 3OC6-HSL bound much more loosely to QscR than other acyl-HSLs tested, we were abl

294 nt gene pools (Q1, Q2 and Q3), corresponding loosely to the west, central and eastern MB, respectivel

295 ng sintered samples, which ranged from being loosely to very well consolidated.

296 peculate that temperature drives Aqy1 from a loosely- to a tightly-blocked state.

297 d personal linkages bind these organisations loosely together as components of an international nutri

298 uclei lack direct sensory input and are only loosely topographically organized, forming interlocking

299 nations, the challenges are compounded by a loosely understood association of pelagic stocks to the

300 The ULK1 EAT domain interacts loosely with the NTD dimer, while the ATG13:ATG101 HORMA