ライフサイエンスコーパス: loosen

1 re and its association with the central pair loosens.

2 could do so when quaternary restraints were loosened.

3 interactions of the adjacent C terminus are loosened.

4 is disorders, including mechanical or septic loosening.

5 intercellular gaps below TJs and cell matrix loosening.

6 ion of periprosthetic osteolysis and aseptic loosening.

7 r, such as osteoporosis and prosthetic joint loosening.

8 increase wall plasticity by a process called loosening.

9 ins known as expansins are mediators of wall loosening.

10 d in enhancing growth by mediating cell wall loosening.

11 nt of osteolysis-associated prosthetic joint loosening.

12 ear debris-associated osteolysis and aseptic loosening.

13 on can contribute to both wall-assembly and -loosening.

14 the cell wall are reduced by continued wall loosening.

15 us contribute to both wall-assembly and wall-loosening.

16 arthritis, periodontitis and peri-prosthetic loosening.

17 nal radiography in diagnosing hip prosthesis loosening.

18 ing fast response during bolt tightening and loosening.

19 ogistic regression assessed risk factors for loosening.

20 /HYDROLASE (XTH) genes involved in cell wall loosening.

21 e apoplast acidification and mechanical wall loosening.

22 done using cyanoacrylate to prevent abutment loosening.

23 rther modification of histones and chromatin loosening.

24 ding unique insight into the mechanism of CW loosening.

25 polyethylene wear (including osteolysis and loosening); 0.652-0.783 sensitivity and 0.976-0.988 spec

26 uding 90 from subjects with NIAF (23 aseptic loosening, 35 instability, 10 stiffness, five osteolysis

27 in esterification and/or abundance impact CW loosening, a process required for CW extension during wh

28 The wall-loosening actions of beta-expansins are known primarily

29 amine reduced cell wall binding but not wall loosening activities.

30 ial for its plant cell wall binding and wall loosening activities.

31 se binding and concomitantly eliminated wall loosening activity measured either by cell wall extensio

32 t this cavity is essential for the cell wall-loosening activity of LTP.

33 The proteins had substantial wall loosening activity, but no detectable proteolytic activi

34 ine or asparagine completely eliminated wall loosening activity.

35 family and have been shown to have cell wall-loosening activity.

36 adiography for diagnosing patellar component loosening after total knee arthroplasty.

37 Chromatin loosens after the invasion of the red blood cell and the

38 of structural covariance by age 25 y, which loosens after the seventh decade of life.

39 f innermost microfibrils, implying that wall loosening agents act selectively on the cross-linking po

40 expansins function endogenously as cell-wall-loosening agents and indicate that expansins have versat

41 Loosening agents that act on xylans and pectins elicited

42 that XTHs do not represent primary cell wall-loosening agents.

43 Our results show that wall loosening alters microfibril connectivity, enabling micr

44 administered in a two-stage process to first loosen and then graft bone particulate under the Schneid

45 f cell membrane makes bilayer structure more loosen and vulnerable.

46 c phase, with some of those being a stack of loosened and distorted close-packed layer of atoms.

47 st of disease spread when NPIs are partially loosened and gives policymakers better data for making i

48 HU values were compared between the loosened and intact screws.

49 unravelled the efficacy of cell-cell contact loosening and 3D emigration into an environment mimickin

50 ymerase 1 protein (PARP1) mediates chromatin loosening and activates the transcription of inducible g

51 ryos indicates a potential role in cell wall loosening and anisotropic growth together with pectin de

52 We propose that chromatin loosening and associated initiation of gene expression i

53 in sensitivity [6], which promotes cell-wall loosening and drives elongation growth.

54 lating important genes involved in cell wall loosening and expansion process.

55 litis, and bone damage, resulting in implant loosening and failure.

56 sue results from a balance between cell wall loosening and intracellular pressure.

57 ively distinguish between aseptic prosthesis loosening and low-grade joint infection, and which bioma

58 n differentiating between aseptic prosthesis loosening and low-grade joint infection.

59 wall structure leading to modulation of wall loosening and plant growth.

60 Pase activation, which facilitates cell wall loosening and solute uptake.

61 is not a likely mechanism of plant cell wall loosening and that the pollen allergen class of beta-exp

62 The difference between loosening and tightening torque value was also measured.

63 ides a new way to study the dynamics of wall loosening and to measure the wall yield threshold and th

64 ll expansion is controlled primarily by wall loosening and yielding.

65 habetaE interface forming the "empty" E site loosens and singly charged Pi readily escapes to the P l

66 a disorganized outer AF (OAF) with thinner, loosened, and disconnected fiber alignment.

67 ly in Arabidopsis, are involved in cell wall loosening, and have been implicated in various aspects o

68 surgery, including pseudoarthrosis, hardware loosening, and recurrent or residual disk herniation.

69 orthopedics and is known to provoke aseptic loosening around arthroplasties and is associated with i

70 me and high pressure (HP) improved the shell-loosening at different degrees, which were observed as g

71 face assessment may be helpful in diagnosing loosening at MRI.

72 on of a total elbow arthroplasty for aseptic loosening between 1996 and 2008 were identified.

73 ave also shown that chloroform significantly loosens both cholesterol-poor and cholesterol-rich membr

74 There was no prosthesis loosening, breakage, or infection leading to removal aft

75 unlikely to play a role in acid-induced wall loosening but may function in cold acclimation or cold-t

76 s show that xyloglucan is important for wall loosening by alpha-expansin, and the smaller size of the

77 of action and effects on wall rheology, wall loosening by Cel12A differs qualitatively from the actio

78 tional change, which spatially separates, or loosens, Cav1 molecules within the oligomeric caveolar c

79 llen allergen class of beta-expansins do not loosen cell walls via a proteolytic mechanism.

80 displayed an irregular, elongated shape with loosened cell-cell adhesions and a reduction in E-cadher

81 cytoskeletal organizer RhoA, consequentially loosening cell substrate grip and enhancing movement.

82 1-YAP-mediated downregulation of E-cadherin, loosening cell-cell contacts, and YAP-TRIO-Merlin mediat

83 EXPB1 selectively loosens cell walls (CWs) of grasses, but its specific bi

84 osynthesis, cuticular changes, and cell-wall loosening-changes that are accompanied by a decline of a

85 tions and are targeted to gene promoters to 'loosen' chromatin for access of transcription factors.

86 ity via the polarized excretion of cell wall-loosening compounds at the tip.

87 (siRNA)-mediated loss of VAPB or PTPIP51 to loosen contacts stimulates, autophagosome formation.

88 teins and describes how wall stress and wall loosening cooperatively result in cell wall growth.

89 he turn connecting H1 and H2 being formed, a loosened core, and H4 partially unfolded and detached fr

90 te cell proliferation, growth, and cell wall loosening, corresponded to the phenotypic severity of th

91 n yeast, mutations affecting the same region loosen coupling between the proton motive force and ATP

92 chanical stiffness), yet did not induce wall loosening (creep).

93 gs through imperfect but workable steps that loosen deadlock, generate momentum for further policy ac

94 olted joint loosening torque: BoltWISE (Bolt loosening detection with innovative sensors).

95 ting within individual solenoid segments and loosens DNA-end binding.

96 plant is believed to be a major component of loosening due to debris-induced changes in bone cell fun

97 Shell-loosening due to HP100 and Endocut-03L was mainly caused

98 CWs are loosened during growth by expansin proteins, which weake

99 acterised by their ability to stimulate wall loosening during cell expansion.

100 iochemical and biophysical mechanism of wall loosening during cell growth are discussed.

101 role of these genes in regulating cell wall loosening during fruit growth, not in ripening-associate

102 could be explained by the putative cell-wall loosening effect of the in tandem starch binding domains

103 ct on the shell collagen, lowering its shell-loosening effect.

104 transglycosylase (XET), a putative cell-wall-loosening enzyme active during germination, expansion, a

105 ease of BLCs by acting through the cell wall-loosening enzyme CEL5.

106 Cell wall-loosening enzymes such as CELLULASE5 (CEL5) and a pectin

107 acidification, thereby activating cell wall-loosening enzymes that enable cell expansion in shoots.

108 ivated two EXPANSIN genes encoding cell wall-loosening enzymes; HBI1's DNA binding and transcriptiona

109 is thought to be catalyzed by elusive "wall-loosening" enzymes.

110 o the behavior of leukocytes, which actively loosen epithelial junctions to migrate, and raise the po

111 e EXPA (alpha-expansin) family were found to loosen eudicot cell walls but to be less effective on gr

112 idopsis seeds, we demonstrate that cell-wall-loosening EXPANSIN (EXPA) genes promote gibberellic acid

113 ent expression of the gene encoding the wall-loosening factor XTH33 as a test case for development- a

114 a membrane H+-ATPase and resultant acid wall loosening; FC produced both hyperpolarization and proton

115 STLD plans and late-stage cancer diagnosis, loosened federal restrictions on STLD plans in 2018 were

116 lants overexpressed genes encoding cell wall loosening functions associated with cell expansion, and

117 The shell-loosening gap induced by an endoprotease with broad spec

118 a-to-stroma interface; vimentin was found in loosened graft stroma.

119 with previous results, we propose that EXPB1 loosens grass CWs by disrupting noncovalent junctions be

120 A lower incidence of loosening has been found for cobalt chrome-cemented comp

121 t92E is always tight in GSCs and immediately loosened in differentiating daughter cells, gonialblasts

122 a surrogate for BMD, were unrelated to screw loosening in DDS.

123 pacts on lumbar fusion, its effects on screw loosening in dynamic stabilization remain elusive.

124 sential components of acid-induced cell wall loosening in plants.

125 p proteins in the nucleus concomitant with a loosening in the association between plasmid molecules.

126 outer cells, which directly inhibited their loosening in the elongation zone.

127 e propose that HMS is required for cell wall loosening in the embryo to facilitate cell expansion dur

128 l change in the target and mechanism of wall loosening in the grass lineage possible, involving a new

129 ntribute directly to the enhancement of wall loosening in this region.

130 is a major source of dislocation and aseptic loosening in total hip arthroplasty (THA).

131 Aseptic loosening is a major complication of prosthetic joint su

132 Wall-loosening is a prerequisite for cell wall expansion, a p

133 We tested the hypothesis that implant loosening is associated with changes in the gut microbio

134 one physiology, however, its role in implant loosening is currently unknown.

135 osening, mainly when bonding is weakening or loosening is occurring.

136 Shell-loosening is of importance in facilitating shrimp peelin

137 Second, this wall loosening is triggered by the selective de-methylesterif

138 canning requires that the enzyme transiently loosen its grip on DNA to allow stochastic movement alon

139 s structural ordering throughout gp120 while loosening its association with gp41.

140 low-affinity Mg2+ sites are filled, T4 pol "loosens its grip" on the primer terminus, as shown by a

141 he bacteria to cross the endothelium through loosened junctions.

142 may be attributable to revisions for aseptic loosening/lysis, infection, and progression of OA (i.e.,

143 macro-scale interface bonding, debonding or loosening, mainly when bonding is weakening or loosening

144 ollen also secretes an unusual expansin that loosens maternal cell walls to aid penetration of the st

145 Such local loosening may facilitate transcription and may transient

146 connectivity in CML, reflecting potentially loosened molecular regulation.

147 In mice, inhaled mucolytic treatment loosens mucus mesh, enhances mucociliary clearance, and

148 nature of a "pretransition" conformationally loosened native state.

149 ape from I(trap) and that escape is aided by loosening nearby native structural constraints, presumab

150 ibosomal proteins, cell cycle, and cell wall loosening, necessary for cytoplasmic growth and cell pro

151 teins called expansins that nonenzymatically loosen noncovalent bonding between cellulose microfibril

152 N-terminal lobe, its binding leading to the loosening of a flap, which in unliganded NMT structures,

153 ular cell adhesion molecule 1, disruption or loosening of adherens junctions, and targeted recycling

154 ular cell adhesion molecule-1, disruption or loosening of adherens junctions, and targeted recycling

155 fine-tuned balance between the formation and loosening of adhesive contacts, a process involving inte

156 These findings imply that the historical loosening of American culture was associated with a trad

157 Loosening of associations has long been considered a cor

158 th arguments that IPL abnormality relates to loosening of associations in SZ.

159 ysfunction in these regions may explain the "loosening of associations" that Bleuler considered to be

160 ion-engendered stimulation of PDK2 activity; loosening of binding as a result of adenine nucleotides

161 The first change is a loosening of cell contact at the apical side of cells on

162 Although the loosening of cells from the biofilm structure was observ

163 at elicited elongation of cells and apparent loosening of cellular junctions upon incubation with Ver

164 n of tight junctional components and dynamic loosening of cellular tight junctions.

165 Whether loosening of cohesion at the onset of mitosis facilitate

166 ase and Ca(2+) chelation lead primarily to a loosening of contacts within the protein shell, resultin

167 ns in the weak dimer-dimer interface suggest loosening of critical intersubunit contacts which likely

168 in confers position-dependent tightening and loosening of guide-strand-target interactions.

169 olent course and was thought to have aseptic loosening of his prosthesis until the time of surgery.

170 Affected skin demonstrated loosening of intercellular connections, disruption of de

171 ion of Tiam1 to the membrane ruffles and the loosening of intercellular junctions.

172 riving transmission and how these affect the loosening of interventions is crucial.

173 mmetry breaking is preceded by an asymmetric loosening of longitudinal, as compared to transverse, an

174 ng to increased histone H4 acetylation and a loosening of nucleosomal-DNA interactions allowing "open

175 Aseptic loosening of orthopaedic implants is induced by wear par

176 erial colonization may contribute to aseptic loosening of orthopaedic implants.

177 edia, periodontitis, endodontic lesions, and loosening of orthopedic implants caused by lipopolysacch

178 Aseptic loosening of orthopedic implants is an inflammatory dise

179 such as osteoporosis, fracture healing, and loosening of orthopedic implants.

180 n Drosophila larval salivary glands, a local loosening of polytene chromatin structure associated wit

181 ure or binding to model membranes promoted a loosening of PPXD and C-domain association, while ADP bi

182 bone resorption that accompanies the aseptic loosening of prosthetic joints.

183 native like conformation, besides a moderate loosening of protein folding.

184 experiments have highlighted tightening and loosening of protein structures upon ligand binding, wit

185 Although cell wall loosening of some form appears to be involved, taken tog

186 Loosening of sutures occurred in 20%, and Descemet detac

187 to LA to HA is associated with a progressive loosening of T state constraints within the hinge and sw

188 served in the rad6Delta strain, suggesting a loosening of target specificity in this mutant that lack

189 ments show that unfolding commences with the loosening of tertiary interactions in a native-like inte

190 and the active site 16 A away, leading to a loosening of the active site.

191 ich indeed occurs with a hitherto unreported loosening of the amide backbones of the haemoglobin mono

192 We conclude that the loosening of the array of myosin heads that occurs on ac

193 at detachment was associated with an overall loosening of the biofilm structure and a release of indi

194 n at the 5'-hydroxymethyl group which causes loosening of the C5'-H5' bonds during the reaction coord

195 understand the phenomena of disassembly and loosening of the cell wall, specifically in the fruit ri

196 weakened xylem could result from rupture or loosening of the cellulosic mesh of interconduit pit mem

197 We suggest that PG is involved in cell wall loosening of the endosperm necessary for radicle protrus

198 mplicated in the control of plant growth via loosening of the extracellular matrix.

199 analogues, consistent with an enlargement or loosening of the headgroup binding domain and a decrease

200 Loosening of the heads from the filament surface enables

201 ribonucleoprotein core with disordering and loosening of the individual protein components.

202 parison with the active structure shows that loosening of the latch contributes but is not central to

203 Loosening of the plug by lateral gate opening, a potenti

204 he degradation of the middle lamella and the loosening of the primary cell wall surrounding cells in

205 2.5%), crural fractures (4 patients, 2.5%), loosening of the prosthesis (3 patients, 1.9%), joint di

206 t Abeta in vivo is a metalloprotein, and the loosening of the structure following chelation treatment

207 t to the active site, facilitated by thermal loosening of the substrate, may lead to the first transi

208 rotein may be direct evidence for a relative loosening of the tertiary fold maintaining the "deleteri

209 extracellular calcium is well known to cause loosening of the tight junction with loss of transepithe

210 the impact of the enforcement and subsequent loosening of these policies on the spread of COVID-19 is

211 y better diagnostic performance in detecting loosening of tibial and femoral components after total k

212 Background Because loosening of total knee arthroplasty (TKA) occurs due to

213 on, a conformational change that involves a "loosening" of the beta-barrels and a loss or shift of di

214 broadening of amide features, indicating a "loosening" of the beta-structure.

215 By allowing the "loosening" of TJs and an increase in paracellular permea

216 en considered in terms of the tightening, or loosening, of receptor structures that respectively occu

217 ntry and that the pollen secrete proteins to loosen or become new wall constituents of the tube and t

218 Bolts and screws are, however, prone to loosening or separating due to factors such as shock, vi

219 Thus, the "loosening" or "remodeling" caused by this point mutation

220 ) testing it on a second patient data set by loosening our filtering criteria, (C) cross-validating w

221 Expansins are small proteins that loosen plant cell walls and cellulosic materials without

222 EXLX1, a bacterial expansin with ability to loosen plant cell walls and whose domain D2 has type-A C

223 ectin methyl esterase (PME) to strengthen or loosen plant cell walls that contain pectin, including s

224 Similarly, ablation of retinoid X receptors loosens PML/RARA DNA binding, inducing terminal differen

225 er ligands, with two different approaches of loosened point chirality, lead to a significant breakdow

226 y to be more common in patients with aseptic loosening, prior studies have focused on LPS, a TLR4-spe

227 postoperative fractures, implant failures or loosening problems occurred; mean Musculoskeletal Tumor

228 At imaging, diagnosis of loosening prosthesis was made for -periprosthetic radiol

229 is indicative of the action of the cell wall-loosening protein expansin.

230 L1-box cis-element, including two cell wall loosening protein genes GhRDL1 and GhEXPA1.

231 Here, we report a type of cell wall-loosening protein that does not share any homology with

232 oup of the beta-expansin family of cell wall loosening proteins in plants.

233 Expansins are plant cell wall-loosening proteins involved in adaptive responses to env

234 ns comprise a superfamily of plant cell wall loosening proteins that can be divided into four individ

235 Expansins are cell-wall-loosening proteins that induce stress relaxation and ext

236 Expansins are wall-loosening proteins that promote the extension of primary

237 ycosylase/hydrolase genes encoding cell wall-loosening proteins was enhanced in SHYG overexpressors b

238 d through EXPA-mediated control of cell wall loosening, providing a mechanistic explanation for this

239 Hydrogen bonds to the peptide backbone are loosened rapidly compared with the 5-ns temperature jump

240 Aseptic implant loosening related to implant wear particle-induced infla

241 ng the wall, the increased pH abrogates wall loosening required for cell expansion and growth.

242 The long-term chromatin loosening required to sustain transcription takes place

243 ally restores channel function presumably by loosening restraints for tilting.

244 Our results could inform NSP policy to loosen restricted-exchange practice, allowing PWIDs grea

245 In October 2018, federal regulations loosened restrictions on STLD plans by extending the all

246 atients and 918 screws were analyzed with 78 loosened screws found in 36 patients (mean follow-up: 43

247 s, and need to be revised, most commonly for loosening secondary to wear or dislocation.

248 ss how allelic diversity of CMT1 may reflect loosened selective constraints in a self-fertilizing spe

249 s from patients with septic joint prosthesis loosening (septic total arthroplasty [SeTA]; 9 specimens

250 Tightening and loosening show that ligand binding respectively stabilis

251 n of pADPr, which maintains chromatin in the loosened state around a certain locus so that the transc

252 are used cautiously so as not to excessively loosen stools and exacerbate anal incontinence.

253 They appear to have wall-loosening, structural, and enzymatic functions.

254 while a reduction in proliferation potential loosens such inhibition and facilitates frequent CSC div

255 with higher ligand reactivity that exhibit "loosened" T state constraints within the globin includin

256 the dilysine pair form the driving force to loosen the cleft, exposing iron; the nearby anion (or ch

257 pe and mutant expansins, we conclude that to loosen the CW, expansin binds highly specific cellulose

258 Furthermore, when we loosen the elastic connection between the heads, the mod

259 einase activity and suggested that expansins loosen the plant cell wall via proteolysis.

260 a good deal of further work has been done to loosen the restrictions and allay concerns about the ris

261 iation, which exposed hydrophobic groups and loosened the structure.

262 TPases) to facilitate cell expansion by both loosening the cell wall through acidification and promot

263 the pollen tube into the maternal tissues by loosening the cell walls of the grass stigma and style.

264 Histone acetylation is crucial for loosening the chromatin structure and facilitating acces

265 Sly1 facilitates SNARE complex formation by loosening the closed conformation of Sed5.

266 99, McMichael's "Prisoners of the Proximate: Loosening the Constraints on Epidemiology in an Age of C

267 " conformation of the repressor, effectively loosening the dimer interface and allowing the repressor

268 3 to destabilize the "on" signaling state by loosening the four-helix bundle.

269 l isomers that can be interconverted only by loosening the knot.

270 s were detected in the mitochondrial genome, loosening the linkage disequilibrium between the organel

271 a pro-oxidant that is potentially capable of loosening the plant cell wall and/or triggering an oxida

272 removal of the Mg2+ from the ternary complex loosens the aromatic side chain packing but leaves the s

273 The mutation M16I loosens the hydrophobic core in the G domain and affects

274 oplasmic-transmembrane domains significantly loosens the inner membrane clasp.

275 y by M. avium subsp. paratuberculosis, which loosens the integrity of the tight junctions.

276 ter reduces the stability of the complex and loosens the interface both in the presence and in the ab

277 This loosens the mannose-binding pocket on the opposite end o

278 ics, area, time and energy, variability then loosens the tight requirements and allows for further sa

279 of HbA perturb the deoxy T state of HbA by "loosening" the contacts associated with the switch regio

280 Several mechanisms have been proposed for 'loosening' the junctions between endothelial cells to en

281 bone loss, which is a key factor in aseptic loosening, the most common reason for joint replacement

282 ulin, and ZO-1 several-fold in glomeruli and loosened their attachment to the actin cytoskeleton.

283 rdware malplacement, three cases of hardware loosening, three perihardware fractures, and two chronic

284 ther with expansins) of controlled cell wall loosening through the transient cleavage and religation

285 Concurrent with the detachment, we find loosened tight junctions between endothelial cells and d

286 ition as well as mechanisms involved in wall loosening to overcome the deleterious effects of soluble

287 ective technique for monitoring bolted joint loosening torque: BoltWISE (Bolt loosening detection wit

288 globule states, the hydration water networks loosen up, and the protein locally becomes more flexible

289 nlargement of the intracellular gate without loosening up the structural integrity.

290 These data suggest that loosening-up the chromatin structure by histone acetylat

291 ombination for the discrimination of aseptic loosening vs low-grade joint infection.

292 n for preoperative discrimination of aseptic loosening vs low-grade joint infection.

293 from those during creep of the enzymatically loosened wall.

294 plies that allergen homologs may function to loosen walls in growing vegetative tissues as well.

295 The degree of shell-loosening was found to be correlated to the extent of pr

296 r components, and an increasing incidence of loosening was shown for cemented acetabular components w

297 help elucidate expansin's mechanism of wall loosening, we determined the structure of EXPB1 by x-ray

298 sensitivity and specificity for arthroplasty loosening were 88% and 91%, respectively, for DECT, 73%

299 olymer assembly, cell wall organization, and loosening were highly enriched in reticulated skin tissu

300 ge, it is possible that LS induces cell wall loosening, which can trigger cell wall damage response.