ライフサイエンスコーパス: loss of vision

1 y progressive retinal cell death and gradual loss of vision.

2 s a common cause of profound and intractable loss of vision.

3 ction, which is consistent with irreversible loss of vision.

4 tress, all of which can lead to debilitating loss of vision.

5 ht ameliorate cellular damage and subsequent loss of vision.

6 ion of diabetic retinopathy and the ultimate loss of vision.

7 CEP290) mutations and subjects have profound loss of vision.

8 rve damage, globe enlargement, and permanent loss of vision.

9 acular degeneration that eventually leads to loss of vision.

10 ve agents of eye infections that can lead to loss of vision.

11 glion cells in the retina, and a progressive loss of vision.

12 glion cell (RGC) pathology and a progressive loss of vision.

13 t bystander destruction of normal tissue and loss of vision.

14 These changes cause a loss of vision.

15 h may damage normal RPE function and lead to loss of vision.

16 , pain, double vision, optic neuropathy, and loss of vision.

17 es may enable treatment to prevent permanent loss of vision.

18 oduct that is mutated in disease, leading to loss of vision.

19 ar deposits, abnormal RPE, and age-dependent loss of vision.

20 Leber's congenital amaurosis, which lead to loss of vision.

21 is a common condition that causes reversible loss of vision.

22 neration of retinal pigmented epithelium and loss of vision.

23 ongenital amaurosis (LCA), which all lead to loss of vision.

24 lead to amblyopia, a permanent uncorrectable loss of vision.

25 rogression of retinal disease and subsequent loss of vision.

26 corneal clarity and can result in permanent loss of vision.

27 vascularization that may minimize iatrogenic loss of vision.

28 of eye diseases that result in catastrophic loss of vision.

29 rd protrusion of the right eye with complete loss of vision.

30 n lead to impaired quality of life (QoL) and loss of vision.

31 f the eye causes keratitis and can lead to a loss of vision.

32 an lead to marked vision impairment and even loss of vision.

33 pathy, markedly distended eyelids and often, loss of vision.

34 ikely to have other ocular complications and loss of vision.

35 re genetic disorders characterized by severe loss of vision.

36 timely treatment that can prevent permanent loss of vision.

37 ein occlusion (RVO) is an important cause of loss of vision.

38 ar-old woman presented with severe bilateral loss of vision.

39 had occlusive retinal vasculitis and severe loss of vision.

40 ive loss of photoreceptors and the permanent loss of vision.

41 the main cell type to degenerate and lead to loss of vision.

42 ted to the hospital with bilateral transient loss of vision.

43 ting diabetic retinopathy and preventing the loss of vision.

44 RGC) axons in glaucoma leads to irreversible loss of vision.

45 ymptoms including headache, papilloedema and loss of vision.

46 eatment resulted in complete reversal of the loss of vision.

47 uch as retinal ganglion cell (RGC) death and loss of vision.

48 itively proved to cause optic neuropathy and loss of vision.

49 n the cornea that leads to tissue damage and loss of vision.

50 lly leading to cell death and, consequently, loss of vision.

51 is pigmentosa, which often results in severe loss of vision.

52 retinal photoreceptor cells and progressive loss of vision.

53 considerable risk of severe and irreversible loss of vision.

54 ted protein methylation leads to progressive loss of vision.

55 loid hemorrhage results in a sudden profound loss of vision.

56 helium, degeneration of the neuroretina, and loss of vision.

57 age related macular degeneration leading to loss of vision.

58 ajor cause of ocular infections and possible loss of vision.

59 ells, causing the deterioration and eventual loss of vision.

60 adaptations to compensate for the unilateral loss of vision.

61 ed cone cell numbers, and led to progressive loss of vision.

62 lude eyelid swelling, ptosis, proptosis, and loss of vision.

63 cally requires aggressive therapy to prevent loss of vision.

64 proliferative diabetic retinopathy can cause loss of vision.

65 ial growth factor (VEGF), macular edema, and loss of vision.

66 here are few treatments and none reverse the loss of vision.

67 ner retinal function in ND4 mice, indicating loss of vision.

68 eptor degenerations that lead to progressive loss of vision.

69 min-positive, perisomatic input preceded the loss of vision.

70 f retinal ganglion cells which could lead to loss of vision.

71 Reasons for loss of vision after BI-KPro implantation most commonly

72 inal degenerations, which cause irreversible loss of vision and are linked to impaired protein degrad

73 retinitis pigmentosa (adRP), which leads to loss of vision and blindness, was investigated in famili

74 clarin1 gene (CLRN1) results in progressive loss of vision and hearing in Usher syndrome IIIA (USH3A

75 type III (USH3) characterized by progressive loss of vision and hearing is caused by mutations in the

76 Most cases consisted of initial loss of vision and intraocular inflammation without prom

77 A 35-year-old pregnant woman presented with loss of vision and metamorphopsia in her left eye.

78 Loss of vision and ocular motility deficit are the most

79 t is a 65 year old who presented with sudden loss of vision and pain following retinal examination us

80 ficant local side effects that can result in loss of vision and possible amblyogenesis.

81 evidence that these problems actually cause loss of vision and potential therapeutic approaches targ

82 sorders that present with neurodegeneration, loss of vision and premature death.

83 rity in disease is reflected in the complete loss of vision and rapid photoreceptor degeneration in t

84 It is characterized by loss of vision and results from mutations in any one of

85 d SN enhancement coevolved to compensate for loss of vision and to help blind cavefish find food in d

86 is the common etiological agent that causes loss of vision and warrants surgical intervention.

87 growth factor, have been shown to stabilise loss of vision and, in some cases, improve vision in ind

88 Potential loss (loss of vision) and gain (freedom from metastasis) were

89 ented during adolescence, with a progressive loss of vision, and culminated in severe visual impairme

90 rs characterized by slow growth, progressive loss of vision, and limited therapeutic options.

91 ssive constriction of the visual fields, and loss of vision, and pathologically by progressive loss o

92 ammatory markers to increase coincident with loss of vision, and RGC functional loss.

93 Headache and visual disturbances including loss of vision are characteristic of GCA.

94 ications, including diabetic retinopathy and loss of vision, are major health concerns.

95 whereas fewer than 1 in 38 will experience a loss of vision as a result of myopia control.

96 erience early in life and remains even after loss of vision as long as feedback from the eyes and hea

97 with their daily life and concerns regarding loss of vision as well as addressing whether they feel s

98 cate that shikonin treatment may prevent the loss of vision associated with DR.

99 e, altered mental functioning, seizures, and loss of vision associated with findings indicating predo

100 ngiogenesis contributes directly to profound loss of vision associated with many diseases of the eye.

101 rea that remains intact for many years after loss of vision attributable to damage to the eyes.

102 hoice for restoring vision or preventing the loss of vision because most blinding diseases originate

103 marked retinopathy consistent with complete loss of vision by 1 month of age.

104 Retinal disease and loss of vision can result from any disruption of the com

105 ects on multiple organ systems; however, the loss of vision caused by diabetic retinopathy might be o

106 Most diseases that cause catastrophic loss of vision do so as a result of abnormal angiogenesi

107 Since most diseases that cause catastrophic loss of vision do so as a result of abnormal ocular angi

108 nces, there is still significant unnecessary loss of vision due to cataract among older African Ameri

109 sa is a sight-threatening disease leading to loss of vision due to corneal inflammation.

110 s attention because it can lead to permanent loss of vision due to foveal involvement by inflammation

111 lly impaired individuals who exhibit partial loss of vision due to inherited retinal dystrophies (IRD

112 esenting with attacks of monocular temporary loss of vision due to intermittent retinal artery occlus

113 cultures of rat retina and, in vivo, prevent loss of vision due to light-induced degeneration of phot

114 ve blinding disease characterized by gradual loss of vision due to optic neuropathy and retinal gangl

115 It may lead to loss of vision due to retinal detachment and chronic inf

116 nal degeneration in mammals causes permanent loss of vision, due to an inability to regenerate natura

117 a Mendelian disease characterized by gradual loss of vision, due to the progressive degeneration of r

118 fications that may play an important role in loss of vision during aging and cataract formation.

119 nges in RPE and photoreceptor morphology and loss of vision during the first postnatal month.

120 aurosis type 4 (LCA4), that manifests as the loss of vision during the first year of life.

121 paranasal sinus disease in association with loss of vision even in the absence of a clear link betwe

122 opacities in the cornea result in bilateral loss of vision, eventually necessitating corneal transpl

123 al manifestations of which include the early loss of vision followed by deterioration of brain functi

124 n of individuals with moderate and/or severe loss of vision following an acute episode of HZO.

125 No unexplained acute loss of vision following Densiron removal was encountere

126 eutic approaches to prevent the irreversible loss of vision from this disease.

127 leading causes of irreversible blindness and loss of vision globally.

128 esultant hyperopic shift, opacification, and loss of vision has recently become a concern.

129 Usher syndrome can cause loss of vision, hearing, and balance.

130 survived had life-changing morbidities (eg, loss of vision in 46% of survivors).

131 ation and early treatment can prevent severe loss of vision in affected patients.

132 n developed countries and often causes rapid loss of vision in age-related macular degeneration.

133 Death of photoreceptors contributes to loss of vision in aging individuals and is associated wi

134 was referred to our center with progressive loss of vision in both eyes 10 days after unintentional

135 Loss of vision in glaucoma is due to apoptotic retinal g

136 Loss of vision in glaucoma occurs because retinal gangli

137 Loss of vision in glaucoma results from the selective de

138 Hemianopia, loss of vision in half of the visual field, results from

139 story, presented to our clinic with painless loss of vision in her left eye.

140 -old woman presented with a sudden, painless loss of vision in her left eye.

141 an lady presented with sudden and persisting loss of vision in her right eye, ocular pain and vomitin

142 esented two days after childbirth for sudden loss of vision in her right eye.

143 last bevacizumab injection because of sudden loss of vision in his left eye caused by a dense vitreou

144 -year-old man presented with sudden painless loss of vision in his left eye.

145 e 3: A 61-year-old man presented with sudden loss of vision in his right eye.

146 generative disorders results in irreversible loss of vision in humans.

147 and young adults, often resulting in severe loss of vision in later life.

148 work demonstrates a metabolic-stress-induced loss of vision in mammals, which has not been described

149 Linkage between low blood glucose and loss of vision in mice may highlight the importance for

150 nsgene in flies led to an activity-dependent loss of vision in older animals and we hypothesized that

151 A 52-year-old male presented with loss of vision in one eye and was diagnosed with NAION.

152 al disease which causes progressive profound loss of vision in patients during their 4th decade.

153 ew treatment for the leading cause of severe loss of vision in patients with age-related macular dege

154 Choroidal neovascularization (CNV) leads to loss of vision in patients with Sorsby Fundus Dystrophy

155 tural history of AMD demonstrates relentless loss of vision in persons who developed advanced AMD.

156 Loss of vision in the absence of clinical or radiologica

157 ration (AMD) is one of the leading causes of loss of vision in the industrialized world.

158 e treatment, the patient still complained of loss of vision in the left eye with a central scotoma.

159 with choroidal neovascularization causing a loss of vision in the majority of patients.

160 utcomes of visual impairment attributable to loss of vision in the non-amblyopic eye.

161 l amblyopia who were visually impaired after loss of vision in their non-amblyopic eye but had no oth

162 Age-dependent loss of vision in these mutant mice is associated with p

163 Visual impairment is the partial or complete loss of vision in which the presenting visual acuity lie

164 rotein retinoschisin (RS1) cause progressive loss of vision in young males, a form of macular degener

165 Here, we report that loss of vision, in the form of dark exposure (DE) for 1

166 Causes of loss of vision included corneal scarring (94.0%), cornea

167 Early loss of vision is classically linked to large-scale cros

168 anges in these behaviors will result in less loss of vision is needed because of the expected increas

169 lly, our only method of slowing glaucomatous loss of vision is to reduce intraocular pressure (IOP),

170 ge-related macular degeneration (AMD), where loss of vision is typically acute and treatment leads to

171 lack of hearing and balance and progressive loss of vision, is caused by mutations in the PCDH15 gen

172 e to the primary visual cortex (V1) causes a loss of vision known as hemianopia or cortically-induced

173 evere neuromotor retardation and progressive loss of vision, leading to blindness by the second decad

174 here is Charles Bonnet syndrome (CBS), where loss of vision leads to complex, vivid visual hallucinat

175 Ten of 84 eyes presented with a loss of vision <20/25.

176 Understanding the processes that lead to loss of vision may lead to preventive strategies.

177 corneal melting (thinning), perforation, and loss of vision may occur.

178 roughout life, serious complications such as loss of vision, mother-to-fetus transmission, and fatal

179 Irreversible loss of vision occurred in one participant who underwent

180 and Cfh(-/-) mice, RPE damage accompanied by loss of vision occurred only in old Cfh(+/-) mice.

181 No clinically visible damage to the eye or loss of vision occurred.

182 Consequently, the loss of vision occurs before the deterioration of brain

183 One patient met a primary endpoint with a loss of vision of 10 letters or more from baseline in on

184 atient presented with sudden onset bilateral loss of vision of one week duration.

185 wer or 10 or more injections associated with loss of vision or a plateau, respectively.

186 For instance, loss of vision or audition leads to the brain areas norm

187 s, MEK inhibitors did not cause irreversible loss of vision or serious eye damage.

188 s, ERK inhibitors did not cause irreversible loss of vision or serious eye damage; retinopathy was se

189 l hypertension (IIH) can present with severe loss of vision or with ongoing vision loss despite maxim

190 All subjects presented with acute loss of vision owing to a subfoveal hemorrhage secondary

191 causes and factors associated with permanent loss of vision owing to HZO.

192 stress have been found to correlate with the loss of vision, particularly in cones, the type of photo

193 Our results suggest that loss of vision produces distinct circuit changes in the

194 Early loss of vision produces dramatic changes in the function

195 longed post-operative positioning, temporary loss of vision, raised intra-ocular pressure, cataract f

196 cutive patients with diabetes without recent loss of vision referred for retinal control were assesse

197 The 10-year probability of loss of vision related to glaucoma was 1.0% after EK, 2.

198 as associated with vision deterioration, but loss of vision remained exceptional.

199 uveitis are associated with severe permanent loss of vision secondary to HZO.

200 us, therapeutic intervention following early loss of vision should focus not only on restoring vision

201 tments.SIGNIFICANCE STATEMENT Amblyopia is a loss of vision that affects 2-5% of children across the

202 Cortical blindness refers to the loss of vision that occurs after destruction of the prim

203 , FGFR inhibitors did not cause irreversible loss of vision; the retinopathy was self-limited and did

204 ively in the primary visual cortex, in which loss of vision to one eye permanently degrades cortical

205 id not affect photoreceptor function, and no loss of vision was seen with kinase-dead transgenics.

206 cal course is characterized by a progressive loss of vision with a slow rate of decline, providing a

207 6 year old female patient who had unilateral loss of vision with signs of retrobulbar optic neuritis

208 CRB1 mutations lead to early-onset severe loss of vision with thickened, disorganized, nonseeing r

209 icits as well as motor deficits and complete loss of vision, with a reduced lifespan of 17 +/- 1 mont