ライフサイエンスコーパス: luminal

1 mandible, 94% of UAMs (29/31, including 8/8 luminal, 6/8 intraluminal, and 15/15 mural subtypes) and

2 filtrating ductal carcinoma (IDC, 84.9%) and luminal A (LA, 49.1%); the mean size of the lesions was

3 ed more complex lipid profiles compared with luminal A and HER2 subtypes.

4 NLR-BC association was more pronounced among Luminal A BC (multivariable OR for the highest category

5 By implementing a morphometry assay with luminal A breast cancer, we demonstrate the potential of

6 igher levels of immune markers compared with luminal A in primary tumors and ALNs(-).

7 e signal in basal-like breast cancer than in luminal A or luminal B subtypes.

8 y tumor and ALNs(-) were associated with the luminal A or TNBC subtype.

9 We identified a subset of luminal A primary breast tumors that give rise to HER2-e

10 ells in the ALNs(-) were associated with the luminal A subtype.

11 , and that its expression is undetectable in luminal A, luminal B, and HER2+ subtypes, as well as in

12 group with long survival were classified as luminal A, whereas triple-negative tumors predominantly

13 with middle quantiles were 5.63 and 3.02 for luminal A-like and triple-negative disease, respectively

14 all known susceptibility loci was 54.2% for luminal A-like disease and 37.6% for triple-negative dis

15 s 74% [59 of 80], respectively; P = .89), or luminal A-like subtype (53% [19 of 36] vs 46% [37 of 81]

16 of markers related to immune tolerance than luminal A.

17 atp6ap1b, revealed specific requirements for luminal acidification in apical, but not basolateral, me

18 Thus, luminal acidification plays distinct and specific roles

19 Although Hodor sustains gut luminal acidity and restrains microbial loads, its effec

20 ntain CD8 T cell tolerance toward intestinal luminal Ags by gavaging wild-type and Muc2(-/-) mice wit

21 toire of developing thymocytes by intestinal luminal Ags.

22 lpha(+) cells make a de novo contribution to luminal and basal epithelia during mammary morphogenesis

23 tivation cooperate to disrupt the balance of luminal and basal gene expression in bladder cells.

24 e analyzed the mRNA expressions of signature luminal and basal genes in bladder cancer tumor samples

25 cific enhancers that differed between normal luminal and basal mammary cells.

26 d into two molecular subtypes referred to as luminal and basal with distinct clinical behaviors and s

27 ton (LINC) complex that is connected in both luminal and extraluminal domains at the site of SPB inse

28 expression was decreased in breast cancer of luminal and HER2 subtypes and inversely correlated with

29 more sensitive to TAK1 inhibitor compared to luminal and HER2(+) cell lines.

30 o, but had no effect on the proliferation of luminal and HER2+ cancer cells and normal breast cells.

31 carcinoma in situ (DCIS) from patients with luminal and HER2-positive breast cancer.

32 ere experimental challenge in distinguishing luminal and membrane-associated NE proteins.

33 gastrointestinal (GI) tract with exposure to luminal and mucosal factors.

34 ogenitors establish long-term clones of both luminal and myoepithelial lineages in adult animals, and

35 ns (P < 0.05) in opposite directions between luminal and non-luminal subtypes.

36 and polarization of T cells against the same luminal antigen differ between gLNs, with the proximal s

37 cells that forms a tight barrier, separating luminal antigens and microbes from underlying tissue com

38 Total choroidal area (TCA), luminal area (LA), and the choroidal vascularity index (

39 Total choroidal area, luminal area and stromal area were all significantly dec

40 were compared with epithelial, stromal, and luminal area fractions (f(epithelium), f(stroma), f(lume

41 e effect of C- and N-terminal tagging of the luminal ATPase torsinA on its ability to associate with

42 Moreover, luminal B and triple-negative subtypes showed more compl

43 l tumors was associated with poor outcome in luminal B cancers.

44 ) recapitulate several key features of human luminal B HR(+)HER2(-) BC, including limited immune infi

45 asal-like breast cancer than in luminal A or luminal B subtypes.

46 its expression is undetectable in luminal A, luminal B, and HER2+ subtypes, as well as in normal brea

47 t diagnosis in patients with HER2+ (n = 28), luminal B-like (n = 49) and triple-negative (n = 38) bre

48 us system (ENS) exists in close proximity to luminal bacteria.

49 n the size of labelled EVs was detected with luminal binding dye molecules such as 5-(and-6)-carboxyf

50 Hrd3 and Yos9 jointly create a luminal binding site that recognizes glycosylated substr

51 absence of HAI-2, including villous atrophy, luminal bleeding, loss of mucin-producing goblet cells,

52 hat leads to the growth of these subcellular luminal branches or makes them progress through a partic

53 excess of Shot induces ectopic acentrosomal luminal branching points in the embryonic and larval tra

54 In contrast, luminal breast cancer and non-transformed mammary cells

55 through binding with its promoter region in luminal breast cancer cell lines and indirectly through

56 -expressing TNBC cells but not LIPG-negative luminal breast cancer cells.

57 the use of RANK pathway inhibitors to prime luminal breast cancer for immunotherapy.

58 Luminal breast cancer gene expression and proliferation

59 ownmodulation of miR-223 as an early step in luminal breast cancer onset and suggest that it could be

60 sential role of AP-2gamma in maintaining the luminal breast cancer phenotype and provide evidence tha

61 r Protein 2gamma (TFAP2C, AP-2gamma) governs luminal breast cancer phenotype through direct and indir

62 In vivo, DC3s infiltrated luminal breast cancer primary tumors, and DC3 infiltrati

63 -223 expression and miR-223 ablation induced luminal breast cancer resistance to CDK4/6 inhibition, b

64 gray-scale US features may help distinguish luminal breast cancers from triple-negative and human ep

65 and 25% in a cohort comprising predominantly luminal breast cancers.

66 ditional fluorescence fluctuation signal for luminal, but not for membrane-bound, proteins.

67 prostate lineage hierarchy, identifies Dist-Luminal-C cells as the luminal progenitor cell populatio

68 Lineage tracing of Luminal-C cells indicated that Dist-Luminal-C cells reco

69 Luminal-C cells located at the distal prostate invaginat

70 acing of Luminal-C cells indicated that Dist-Luminal-C cells reconstituted distal prostate luminal li

71 Deletion of Pten in Dist-Luminal-C cells resulted in prostatic intraepithelial ne

72 state cells and confirmed the existence of h-Luminal-C cells.

73 stal prostate invagination tips (termed Dist-Luminal-C) exhibited greater capacity for organoid forma

74 minal cell type (termed type C luminal cell (Luminal-C)) marked by Tacstd2, Ck4 and Psca expression.

75 ligands and processes, its regulation by ER-luminal Ca(2+) concentration ([Ca(2+)](ER)) is poorly un

76 In outline, STIM1 senses an ER-luminal calcium decrease, relocalizes to ER-PM junctions

77 EPN1 is a ER calcium sensor that responds to luminal calcium depletion, changing its oligomeric state

78 Luminal calcium levels are determined by calcium-sensing

79 ia this domain, SEPN1 responds to diminished luminal calcium levels, dynamically changing its oligome

80 nct from the previously identified NKX3.1(+) luminal castration-resistant cells.

81 form two "half-channels" with cytosolic and luminal cavities, respectively, and lateral gates facing

82 ed a unique luminal cell type (termed type C luminal cell (Luminal-C)) marked by Tacstd2, Ck4 and Psc

83 We show that both types of the luminal cell are susceptible to oncogenic transformation

84 cells have been identified in both basal and luminal cell compartments.

85 tudy elucidates a role for TET2 in governing luminal cell differentiation and endocrine response that

86 C ablation, BSCs activate a hybrid basal and luminal cell differentiation program before giving rise

87 Increased differentiation correlated with a luminal cell fate that could be reversed by inhibition o

88 urrounding many genes that are important for luminal cell fate, and supported the transcription of th

89 er a critical role for ARID1A in maintaining luminal cell identity and endocrine therapeutic response

90 rom mouse prostates, and identified a unique luminal cell type (termed type C luminal cell (Luminal-C

91 iate in culture to generate mature basal and luminal cell types, including ER+ cells that have been c

92 lands, are composed of basal cells (BCs) and luminal cells (LCs)(1,2).

93 1 marks a specific subpopulation of proximal luminal cells (PLCs), enriched in the periurethral regio

94 epithelium, LEFTY1 expression in a subset of luminal cells and rare basal cells opposes BMP7 to promo

95 rganoid cells derived from the TACSTD2(high) luminal cells are more predisposed to neuroendocrine dif

96 more, we show that mouse distal and proximal luminal cells are most similar to human acinar and ducta

97 t LXN is highly expressed in normal prostate luminal cells but downregulated in high Gleason grade ca

98 The adult mouse prostate luminal cells contain both castration-resistant Sox2-exp

99 ation of both Foxa1 and Pten in intermediate/luminal cells in mice results in development of bladder

100 r cognate receptors expressed in a subset of luminal cells in the mammary epithelium.

101 IL-1alpha is expressed predominantly by luminal cells of the genital tract in response to infect

102 rostate epithelium consists of predominantly luminal cells that express androgen receptor and require

103 s by facilitating a switch from ER-dependent luminal cells to ER-independent basal-like cells.

104 Both TACSTD2(high) and TACSTD2(low) luminal cells transduced by constitutively activated AKT

105 to physically deform the innermost layer of luminal cells, compelling them to discharge the fluid th

106 In basal progenitor-derived luminal cells, Klf5 deacetylation increases their prolif

107 eneration is driven by nearly all persisting luminal cells, not just by rare stem cells.

108 ostates, Klf5 is expressed in both basal and luminal cells, with basal cells preferentially expressin

109 hift from luminal progenitor cells to mature luminal cells.

110 hymal cells acting in a paracrine fashion on luminal cells.

111 of its original size because of the loss of luminal cells.

112 rential effects in HVs pointing to a role of luminal changes.

113 During protein synthesis, ER luminal chaperones are swept along the secretory pathway

114 c cells and requires a high concentration of luminal chaperones to function.

115 hickness (SFCT), total choroidal area (TCA), luminal choroidal area (LCA), and stromal choroidal area

116 as electric shunts for proton pumping and in luminal Cl(-) accumulation.

117 abolite cross-feeding may recover intestinal luminal colonization but not pathogenicity.

118 protein glycosylation was restricted to the luminal compartments of the secretory pathway and on ext

119 contribute to the regeneration of the distal luminal compartments.

120 entify myeloid leukemia factor 2 (MLF2) as a luminal component of the bleb.

121 eviously implied increased propensity for TT luminal concentration imbalances at high electrical stim

122 ia compared with control mice, and a reduced luminal concentration of secretory IgA (SIgA) following

123 tch and systolic shortening serves to mix TT luminal content and assists equilibration with bulk extr

124 to coordinate its contractions to propel the luminal content forward (peristalsis).

125 of ER tubules, decreases the mobility of ER luminal content, and exhibits an affinity to highly curv

126 particularly in response to modifications of luminal content, including nutrients.

127 al and stromal cells that interface with the luminal contents of the female reproductive tract.

128 lymphocytes as well as serum and intestinal luminal contents were assessed for Ag-specific reactivit

129 of crypts lining the epithelium and diverse luminal contents, regulates homeostasis throughout the b

130 001), and very strongly with the severity of luminal coronary stenosis (area stenosis, r=0.83; P<0.00

131 lly regarded as to a source of membranes and luminal degradative enzymes.

132 In the porcine PJ model, the mean luminal diameter and area of the pancreatic duct in the

133 with ensuing esophageal rigidity and loss of luminal diameter caused by strictures.

134 ional units with a basal stem cell niche and luminal differentiated cell zone, stable, linear gradien

135 ble for maintaining basal progenitors, their luminal differentiation, and the proliferation of their

136 or basal progenitors' maintenance and proper luminal differentiation, as deacetylation of Klf5 causes

137 deacetylation of Klf5 causes excess basal-to-luminal differentiation; attenuates androgen-mediated or

138 derived TEVGs show excellent patency without luminal dilation and effectively maintain mechanical and

139 buffering function to deal with the frequent luminal distortions occurring during food intake and mov

140 tion with HIV enhanced such CD3+ CD8+ T cell luminal distribution.

141 oposed model of membrane association for the luminal domain of SUN2, a constituent protein of the lin

142 requires an intact active site in the Man1b1 luminal domain.

143 Jaw1L) are homologous proteins with small ER luminal domains and large cytoplasmic domains.

144 m fluctuations by binding this ion through a luminal EF-hand domain.

145 Misfolded luminal endoplasmic reticulum (ER) proteins undergo ER-a

146 r strut coverage by OCT which was defined as luminal endothelial cells with 2 abluminal layers of smo

147 ract enables these neurons to respond to the luminal environment and to induce expression of neuron-s

148 transporting enterocytes interact with their luminal environment using a densely packed collection of

149 ons as a regulatory node that integrates the luminal environment with the physiological output of int

150 e show that the TACSTD2(high) human prostate luminal epithelia cells highly express SOX2 and are rela

151 riven inflammation and promotes expansion of luminal epithelial cell populations that are hypothesize

152 ocrine differentiation of the human prostate luminal epithelial cells induced by caAKT1 and c-Myc and

153 Prostatic luminal epithelial cells secrete high levels of acetylat

154 infiltration and massive desquamation of the luminal epithelial cells.

155 evere tissue injury was evident with loss of luminal epithelial lining and mural stroma necrosis.

156 We observe distal lobe-specific luminal epithelial populations (LumA, LumD, LumL, and Lu

157 astic lesions containing elevated numbers of luminal epithelial progenitor cells, which were surround

158 from the stroma to the epithelium to promote luminal epithelial remodeling during embryo invasion.

159 ty, indicated by a general downregulation of luminal/epithelial differentiation markers and upregulat

160 iated when an embryo attaches to the uterine luminal epithelium and subsequently penetrates into the

161 ole as a lineage survival factor in prostate luminal epithelium.

162 pha induces a potent cytotoxic cell death in luminal (ER+) breast cancer cell lines which fail to upr

163 nduced signature was significantly higher in luminal/ER+ tumor metastases compared with their primari

164 D51AP1 gene transcript was increased in both luminal estrogen receptor-positive breast cancer and bas

165 vered massive macromolecular clusters on the luminal face of EV membranes.

166 (and a little of isoform vC) localize to the luminal face of the endoplasmic reticulum (ER) and to th

167 Particularly, it is unknown what ER luminal factor(s) are involved in ERAD.

168 uch as genetic background, environmental and luminal factors, and mucosal immune dysregulation, have

169 Luminal factors, such as diet and microbiota, regulate n

170 to investigate epithelial cell regulation by luminal factors.

171 ds to gain of TEAD-YAP chromatin binding and luminal features associated with BBDI resistance.

172 population (PrU) that shares both basal and luminal features.

173 er quadrant (RLQ)/pelvis, abscess, and extra-luminal fecalith] on complication rates and resource uti

174 Furthermore, colonic luminal filtrates from the mice transplanted with patien

175 normally present in the intestine, including luminal flow and serosal blood flow (shear force) or per

176 ted by changes in calcium flux under applied luminal flow).

177 capitulate native crypt-villi topography and luminal flow, Nikolaev et al.

178 s the biochemical composition of the uterine luminal fluid (ULF) in the most cranial portion of the u

179 ent of transmembrane segments, cytosolic and luminal funnels in TMCO1 and TMEM147, respectively, sugg

180 acture in the calcium deposits to facilitate luminal gain and stent expansion.

181 nalyzed the protein expressions of signature luminal (GATA3) and basal (KRT5/6) markers by immunohist

182 Exogenous luminal GDNF penetrated aganglionic colon epithelium of

183 evidence that epigenetic mechanisms silence luminal gene expression in the basal phenotype.

184 nt of basal CK5-positive areas in favor of a luminal gene program.

185 tion was associated with lower expression of luminal genes in tumors and FGFR inhibition increased tr

186 arge, flat dysplastic mucosal lesions of the luminal GI tract can be challenging.

187 tissue-like structures, including organized luminal/glandular epithelium, stroma, vascularized mucos

188 induced hyperfiltration wherein increases in luminal glucose at the macula densa upregulate the expre

189 ds and the glycosylated V(o) subunits form a luminal glycan coat critical for V-ATPase folding, local

190 Our results define the architecture of ER-luminal GT-C enzymes and provide a structural basis for

191 NADPH oxidase NOX1 is the primary source of luminal H(2)O(2) early after C. rodentium infection and

192 Thus, Adamts18 links luminal hormone receptor signaling to basement membrane

193 ted by ubiquitylation in models of basal and luminal human breast cancer.

194 h culminates in increased lamina propria and luminal IgA.

195 MMs responded to luminal infection by upregulating a neuroprotective prog

196 oids to genotoxic pks(+) E. coli by repeated luminal injection over five months.

197 ells expressing only TbIP(3)R disclosed that luminal inorganic orthophosphate (P(i)) or pyrophosphate

198 andard test for comparison was endoscopy for luminal inspection and computed tomography (CT) to confi

199 human disease and show genetic targeting of luminal/intermediate cells in mice drives squamous diffe

200 ndosomes and lysosomes requires finely tuned luminal ion homeostasis and transmembrane ion fluxes.

201 The concentration of luminal L-serine is largely dependent on dietary intake.

202 that sphingomyelin, an abundant lipid of the luminal leaflet of BCV membranes, and normally absent fr

203 ug diffusion from the balloon surface to the luminal lesion.

204 e subpopulations before differentiating into luminal-like cells.

205 ivotal role in mammary gland development and luminal lineage commitment.

206 esistance, with associated activation of non-luminal lineage programs.

207 re known to coordinately orchestrate mammary luminal lineage specification and endocrine response, an

208 NF complex targeting to genomic sites of the luminal lineage-determining transcription factors includ

209 uminal-C cells reconstituted distal prostate luminal lineages through self-renewal and differentiatio

210 tagenesis experiments showed that the second luminal loop of CLN6 is required for the interaction of

211 In normal luminal mammary epithelial cells, miR-223 acted cell aut

212 t genes (PGR, KRT8/CK8, BCL2), which are all luminal markers.

213 Here we describe the vulva luminal matrix, which contains chondroitin proteoglycans

214 exerting osmotic pressure that can burst the luminal membrane.

215 and plays critical protective roles against luminal microbes and other noxious agents.

216 exists in dynamic balance with trillions of luminal microbes.

217 tritional supplementation on the mucosal and luminal microbiota along the gastrointestinal tract (GIT

218 light the role that butyrate produced by gut luminal microbiota plays in triggering regulatory pathwa

219 separates the mucosal immune system from the luminal microbiota.

220 elated the abundance of cecal messenger RNA, luminal microflora, physiology, and behavior in a highly

221 PMTs work as dimers and contain a luminal MIR domain with a beta-trefoil fold, which is su

222 Basal and luminal molecular subtypes have been identified that are

223 esigned cyclic peptides enables us to reduce luminal monocyte adhesion and lesion expansion during en

224 vation of FOXA1 and PTEN in intermediate and luminal mouse urothelium.

225 rties between microenvironmental niches, the luminal mucosa and crypts.

226 al-mediated transport system for NADP(+) and luminal NAD(+) biosynthetic enzymes integrate signals fr

227 lly resolved, neutralization of IL-22 caused luminal narrowing of the cecum-a feature reminiscent of

228 imaging is mainly based on the assessment of luminal narrowing rather than abnormalities in the vesse

229 r internal composition rather than degree of luminal narrowing, and conventional imaging techniques m

230 ream, a response that supported abluminal-to-luminal neutrophil TEM.

231 no signs of severe ileus or gastrointestinal luminal obstruction.

232 ed complications, including gastrointestinal luminal obstruction; biliary obstruction; recurrent acut

233 IP5 is critical for the initiation of PCa of luminal origin mediated by Pten-loss whereas it is dispe

234 mal and cancerous breast epithelial cells of luminal origin, flow cytometry characterization, and gen

235 issection of this disease: 1) Most UTUCs are luminal-papillary; 2) UTUC has a T-cell depleted immune

236 ageal dilation might be required to increase luminal patency.

237 into the interstitium, restoring the tubular luminal patency; this was followed by degradation of int

238 n acidocalcisomes or alkalinization of their luminal pH activate TbIP(3)R and Ca(2+) release.

239 Luminal pH and bile salts were determined in duodenal as

240 e the pH dependence of NPQ, showing that the luminal pH is always above 5.5 in vivo and highlighting

241 riphosphatase is required for establishing a luminal pH of 6.1 inside CG using ClopHensorN(Q69M), a n

242 th genetic and pharmacologic perturbation of luminal pH, we monitored transport of newly synthesized

243 type of breast cancer cells by stimulating a luminal phenotype and ultimately modifying the outcome o

244 oneer transcription factor that promotes the luminal phenotype in luminal progenitors, while repressi

245 LumD, LumL, and LumV), a proximally enriched luminal population (LumP) that is not lobe-specific, and

246 le-cell RNA sequencing, we identified a rare luminal population in the mouse prostate that expresses

247 , and old (20 mo) rat donors and assessed if luminal preservation (LP) is effective in delaying IPI.

248 Significant luminal pressure reduction would be necessary to maintai

249 on, and the proliferation of their basal and luminal progenies.

250 rchy, identifies Dist-Luminal-C cells as the luminal progenitor cell population in invagination tips

251 Basal/stem and luminal progenitor cells can differentiate in culture to

252 A1 mutation carriers results in a shift from luminal progenitor cells to mature luminal cells.

253 actor that promotes the luminal phenotype in luminal progenitors, while repressing the basal phenotyp

254 Canonically, MYC up-regulation in luminal prostate cancer cells functions to oppose the te

255 e intracellular vesicles (LICVs) that retain luminal protein content and maintain contact sites with

256 ften together with hydrophilic and folded ER luminal protein parts, is not known.

257 lated by a peripheral membrane-associated ER-luminal protein that strongly inhibits the channel in th

258 We found that luminal proteins violate the Stokes-Einstein relation, w

259 aly in the temperature-dependent mobility of luminal proteins was observed, which was developed into

260 rly folded, ER-resident eroGFP (and other ER luminal proteins) to "reflux" back to the reducing envir

261 velope lumen and, through interaction with a luminal region of the channel, can modify high-[Ca(2+)](

262 ino acid including partial transmembrane and luminal regions and easily aggregates like amyloid beta

263 eously without any reduction in SR [Ca(2+)], luminal regulation, Ca(2+)-dependent inactivation, or ph

264 Mucosal scrapings and luminal samples were collected from the duodenum, jejunu

265 hlemm's canal (SC), theoretically increasing luminal shear stress.

266 ary cilium-an antennae-like structure on the luminal side of the collecting duct.

267 o vasculature-resident cells that patrol the luminal side of the endothelium.

268 y induces mechanical stress initiated on the luminal side of the ER membrane, which may threaten its

269 Their unfolding occurs on the luminal side of the membrane by cytoplasmic Cdc48 action

270 Upon reaching the luminal side, sIgAs mediate host protection and pathogen

271 nd ERBB2-genes which are responsible for the luminal signature in breast cancer.

272 cell survival, increased sizes of intestinal luminal spaces, and restored villi and goblet cell morph

273 he achalasia and GERD groups suggesting that luminal stasis does increase biomarker levels for any of

274 urements also included percentages of artery luminal stenosis and interstitial fibrosis/tubular atrop

275 nterstitial fibrosis/tubular atrophy, artery luminal stenosis, and arteriolar hyalinosis to measure n

276 e Ca(2+) ion was sufficient to stabilize the luminal STIM1 complex.

277 al jejunal function and that survive to form luminal structures after transplantation into the kidney

278 revealed similar differentiated and stemlike luminal subpopulations that likewise acquire enhanced re

279 Luminal substrate segments cross the membrane in an unfo

280 h ERAD components involved in degradation of luminal substrates are well characterized, much less is

281 upported directional tumor evolution through luminal subtypes to increasingly malignant states.

282 stone modifications in relation to basal and luminal subtypes.

283 opposite directions between luminal and non-luminal subtypes.

284 microbiota or Phascolarctobacterium reduced luminal succinate levels and restored colonization resis

285 olarctobacterium reduced the availability of luminal succinate, a crucial metabolite for the growth o

286 In the complex, the luminal surface of CLC-7 is entirely covered by a dimer

287 ound, carbohydrate-rich molecules covers the luminal surface of the endothelium along the entire vasc

288 expressed in multiple tissues including the luminal surface of the gut.

289 The glycocalyx is a layer coating the luminal surface of vascular endothelial cells.

290 nt were obtained in 16 patients and revealed luminal tissue thickening at the inflow and outflow port

291 ntitative classifier referred to as basal to luminal transition (BLT) score which identified the mole

292 iciency elicits a subpopulation of otherwise luminal tumor cells exhibiting basal differentiation tra

293 2/Neu transgenic mice reprograms HER2-driven luminal tumors into basal-like tumors.

294 the less aggressive and most-differentiated luminal tumors to the more aggressive and least-differen

295 t revealed that higher PREX1 mRNA in ER(+ve)/luminal tumors was associated with poor outcome in lumin

296 In luminal tumors, the expression of a subset of these proa

297 ,217 and 6,167 unique proteins in basal- and luminal- tumors, respectively.

298 tially methylated H3K4me1 peaks in basal and luminal tumour samples, suggesting that active enhancers

299 esults in SR/ER membrane destabilization and luminal vacuolization along with decreased myocyte contr

300 ay were investigated and MN penetration into luminal vasculature was confirmed in vivo.