ライフサイエンスコーパス: lung

1 r normalized Vt when compared with noncystic lung.

2 native intestinal ECs relative to kidney and lung.

3 de direct information on exposure within the lung.

4 without increasing viral replication in the lung.

5 a single-cell atlas of the developing human lung.

6 ate IL-33 release and TSLP expression in the lung.

7 bronchodilator inhalation than the proximal lung.

8 gulation of these genes in the premetastatic lungs.

9 was markedly reduced in Src-1/-2(d/d) fetal lungs.

10 ction and 10 age-matched, uninfected control lungs.

11 eptor that is expressed predominantly in the lung(2,4); the same receptor tropism is thought to have

12 5%), and other organs saw similar decreases: lung (-70%), heart (-43%), and liver (-37%).

13 xenogeneic platform provided explanted human lungs a supportive, physiologic milieu and systemic regu

14 software quantification of the extent of CT lung abnormality were predictors of intensive care unit

15 that arise as P. aeruginosa adapts to the CF lung abrogate T6SS activity, making P. aeruginosa and it

16 CT scan imagery found lung abscess in 5 (41.6%) cases.

17 dney disease and 8.15 (95% CI 3.59-18.5) for lung abscess or bronchiectasis.

18 ed by a decrease in PGE(2) production in the lung; accordingly, exogenous administration of PGE(2) re

19 odermal and pulmonary specifying TF GATA6 in lung adenocarcinoma (LUAD) progression.

20 ll lines: acute monocytic leukemia THP-1 and lung adenocarcinoma A549.

21 oming resistance to platinum chemotherapy in lung adenocarcinoma has previously been hampered by inap

22 y aggressive, immunocompetent mouse model of lung adenocarcinoma improves long-term survival and cisp

23 In EGFR-mutated lung adenocarcinoma, EGFR-TKIs show enhanced efficacy in

24 d lung epithelial cells to model early-stage lung adenocarcinoma.

25 for assessing the invasiveness of individual lung adenocarcinomas presenting as subsolid nodules on c

26 Natural lung aging is associated with molecular and physiologica

27 d glycosphingolipid-glycans from total human lungs, along with histological analyses of IAV binding.

28 a fatal disease involving destruction of the lung alveolar structure.

29 eases the respiratory quotient of the native lung and could reduce both the occurrence of alveolar hy

30 ake higher than expected was observed in the lung and heart for up to 24 h.

31 trypsinogen and more edema, infiltration of lung and pancreas by inflammatory cells, and plasma amyl

32 In lung and pancreatic cells, gene ontology analyses of DM

33 ry pressure to increase the fraction of open lung and reduce atelectrauma.

34 ntogeny of airway macrophages (AMs) in human lung and their contribution to disease are poorly mapped

35 ulation of LAM(CORE) cells was identified in lung and uterus of patients with LAM, sharing close tran

36 protects against SARS-CoV-2 infection in the lungs and noses of mice without evidence of immunopathol

37 tional Institutes of Health, National Heart, Lung, and Blood Institute.

38 Radiomics were obtained for the entire lung, and multiple logistic regression analyses with are

39 uding the ear, the brain, the blood, and the lung, and thus in highly diverse and dynamic environment

40 ontrasted chest CT and segments the lesions, lungs, and lobes in three dimensions, based on a dataset

41 rticle delivery of FOXM1 or FOXF1 stimulates lung angiogenesis and alveolarization during recovery fr

42 Disseminated tumors to the bone and lung are easily detected by microCT, while ultrasound pr

43 constitutive levels of Nrf2 in the premature lung are insufficient to mitigate hyperoxia-induced hypo

44 Lungs are one of the main sites of breast cancer metasta

45 The lungs are the main organ involved, and chest X-rays, whe

46 t our designed peptides perturb TJs in human lung as well as human and murine skin epithelium, enabli

47 more iron in the extracellular milieu of the lung associates with distinct clinical phenotypes of COP

48 augmented in plasma, tracheal aspirate, and lung autopsies tissues from COVID-19 patients, and their

49 sG signal, virus was only isolated from some lung, brain, liver, and kidney samples that were ZsG and

50 n similar to that of FSTL-1 Hypo and reduced lung burden compared with the TCRdelta(-/-) controls.

51 FSTL-1 Hypo/TCRdelta(-/-) displayed a lung burden similar to that of FSTL-1 Hypo and reduced l

52 induce higher numbers of T(H) 2 cells in the lung, but those cells release decreased T(H) 2 cytokine

53 inum at the cellular level in non-small cell lung cancer (NSCLC) explant models after treatment with

54 miR-21-5p isolated from human non-small cell lung cancer (NSCLC) tissue possesses 3'-terminal 2'Ome.

55 monocytes from patients with non-small cell lung cancer (NSCLC) where c-MAF is overexpressed.

56 In non-small cell lung cancer (NSCLC), accumulation of anti-inflammatory t

57 s an option for patients with non-small cell lung cancer (NSCLC), distinguishing between N0, N1, and

58 labor between YAP and TAZ in non-small cell lung cancer (NSCLC), the most common histological subtyp

59 ole for proline catabolism in non-small cell lung cancer (NSCLC).

60 lume growth was associated with a history of lung cancer (P < .001), a baseline nodule volume less th

61 lmonary nodules (PN) detection and secondary lung cancer (SLC) diagnosis.

62 Cancer (EORTC) Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13) assesses quality of life (QOL)

63 nd nonsuspicious for cancer in patients with lung cancer and lymphoma by using a convolutional neural

64 ody (18)F-FDG PET/CT images in patients with lung cancer and lymphoma.

65 esses quality of life (QOL) in patients with lung cancer and was the first EORTC module developed for

66 R) by antibody or CRISPR knockout of IL37 in lung cancer cell lines repolarized TAMs, resulting in re

67 d epithelial-mesenchymal transition (EMT) in lung cancer cells and promoted metastatic spreading.

68 A 10-min exposure of A549 human lung cancer cells to sequential 50- and 385-Hz oscillati

69 , the videos of labeled EVs uptake by living lung cancer cells.

70 tion induced by femoral inoculation of Lewis lung cancer cells.

71 ated by 365,307 DNA methylations in the TCGA lung cancer cohort.

72 ne microenvironment plays a critical role in lung cancer control versus progression and metastasis.

73 physical activity with histologic types and lung cancer in ever and never smokers.

74 Up to 12-year lung cancer incidence predicted by CXR-LC.

75 ype-specific regulation of tumor fibrosis in lung cancer is mediated through differential SMAD3 promo

76 screening modalities for early detection of lung cancer might result in the discovery of thyroid inc

77 nfirmed in subcutaneous and orthotopic mouse lung cancer models.

78 atients' receipt of initial assessments by a lung cancer nurse specialist and according to trust-leve

79 ction of postoperative pulmonary function in lung cancer patients before tumor resection is essential

80 thway from smoking to overall survival among lung cancer patients potentially mediated by 365,307 DNA

81 ents and detectable in blood and tumors from lung cancer patients.

82 to improve the management of IPNs.Methods: A Lung Cancer Prediction Convolutional Neural Network mode

83 g CYP2A expression may alter smoking-related lung cancer risk and tissue damage from other inhaled to

84 PET/CT scans of patients with non-small cell lung cancer served as model for three 3-dimensionally pr

85 Remarkably, human lung cancer tissues can only be distinguished from adjac

86 is developed to identify biomarker genes for lung cancer using gene expression profiles.

87 second cause of cancer-related deaths (after lung cancer) among women.

88 q served as potential prognostic markers for lung cancer, and M2 predominance and juxtaposition of M2

89 Lung cancer, the leading cause of cancer mortality, exhi

90 te ratio (NLR) and survival in patients with lung cancer, treated with radiotherapy.

91 stoma, breast cancer, colorectal cancer, and lung cancer.

92 e to Myc-driven lymphoma and Eml4-Alk-driven lung cancer.

93 LC), the most common histological subtype of lung cancer.

94 s for testicular to over 1,000,000 cases for lung cancer.

95 origenesis in human breast and nonsmall cell lung cancer.

96 tertumoral and intratumoral heterogeneity of lung cancers as well as incidences of subtype transdiffe

97 although levels are very low in early-stage lung cancers, ctDNA is present prior to treatment in mos

98 atures derived from yeast were detectable in lung cancers, head and neck cancers and tumors from pati

99 ty (P = .0017), FEV(1) (P = .037), and total lung capacity (P = .013) but not their lung carbon monox

100 total lung capacity (P = .013) but not their lung carbon monoxide diffusion capacity (P = .12).

101 pectively included 79 patients with stage IV lung carcinomas (n=24), renal carcinomas (n=11), or mela

102 e SHH interference in colon, pancreatic, and lung cell lines triggered cell death through PTCH proapo

103 (AT2) cells represent a metabolically active lung cell population important for surfactant biosynthes

104 d survival, reduced fungal burden, increased lung concentrations of proinflammatory cytokines and neu

105 ctive ventilation strategies for the injured lung currently revolve around the use of low Vt, ostensi

106 Decreased lung CYP2A expression may alter smoking-related lung can

107 34) had lower (1.04- to 1.12-fold) levels of lung CYP2A13, CYP2A6, and CYP2A7 (and higher CYP1A2) mRN

108 y monitor the persistence and progression of lung damage.

109 or postnatal expression of genes involved in lung development along with an impaired alveolarization

110 osterone and low prenatal oestrogen inhibits lung development and may predispose individuals to be vu

111 rk reports crucial cellular crosstalk during lung development involving Cyp26b1-expressing endotheliu

112 elium and identifies a novel RA modulator in lung development.

113 Patients with chronic lung disease (other than asthma) were excluded.

114 o distinct stages of progression of COVID-19 lung disease and highlights the need for peripheral bloo

115 ction and can be used to define the basis of lung disease and test immune and antiviral-based counter

116 Allergic asthma is a chronic inflammatory lung disease associated with increased cytokine secretio

117 y predispose individuals to be vulnerable to lung disease in later life.

118 The severity of COVID-19 lung disease is higher in the elderly and people with pr

119 The primary outcome was the severity of lung disease on admission chest radiographs, measured by

120 hat coronary artery disease, but not chronic lung disease, was associated with death among hospitaliz

121 of immune function and the development of CF lung disease.Methods: We performed single-cell RNA seque

122 l facilitate interpretation of risk loci for lung diseases.

123 alidate this approach across a wide range of lung diseases.

124 ncreased susceptibility to acute and chronic lung diseases.

125 calised not only in foamy macrophages in the lungs during infection but also accumulate in polymorpho

126 nduced deviant angiogenic signaling in mouse lung EC and human fetal HPMEC.

127 sing the modified Radiographic Assessment of Lung Edema (mRALE) score.

128 showed that rhIGF-1/BP3 treatment increased lung endothelial cell and alveolar type 2 cell prolifera

129 Primary mouse lung endothelial cells (MLEC) and human umbilical vein e

130 l, Alp1 elicits helper T (Th) cell-dependent lung eosinophilia that is initiated by the rapid respons

131 that it enhances viral replication in human lung epithelial cells and primary human airway tissues b

132 human induced pluripotent stem cell-derived lung epithelial cells to model early-stage lung adenocar

133 sed the presentation of HLA-B, -C, and -E on lung epithelial cells.

134 ntified as one of the key ECM markers in the lung epithelial-mesenchymal interface both at the RNA an

135 The mammalian lung epithelium is composed of a wide array of specializ

136 Lymphatic vessels in the donor lung exhibited active sprouting toward the host at the a

137 Endothelial cells are an integral part in lung fibrosis.

138 ted, but the liver was not enlarged, and the lung fields were clear.

139 ngs in the mediastinum (Fig 1) and bilateral lungs (Figs 2, 3).

140 Lungs from mice undergoing hemorrhagic shock exhibited a

141 acrophages were defined in nondiseased human lungs from smokers and nonsmokers.

142 ate the effects of rare SERPINA1 variants on lung function and emphysema phenotypes in subjects with

143 Spirometry testing was used to measure lung function and gene expression levels were measured u

144 igates the progression of BLM-induced PF and lung function deterioration.

145 have chronic respiratory symptoms and severe lung function impairment, and an increased risk of acute

146 axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has

147 eased alveolar simplification, and preserved lung function in mice reaching adulthood.Conclusions: Na

148 This study highlights the need for lung function surveillance and prevention of LRTIs and P

149 There were no significant changes about lung function test, smoking history, sex and the levels

150 dhood asthma therapies have little effect on lung function trajectory.

151 Symptoms, pre-/post-bronchodilator lung function, atopy, and cleaning exposures were assess

152 siological changes that cause alterations in lung function, diminished pulmonary remodeling and regen

153 bove traditional ARDSnet settings to improve lung function, oxygenation and ventilation/perfusion mat

154 001 may have a rapid and sustained effect on lung function, particularly in patients with type 2 phen

155 on atelectasis, thus optimizing the residual lung function.

156 ing in increased inflammation and diminished lung function.

157 tem asthma control questionnaire (ACQ-6) and lung function.

158 Lung granulomas are organized structures of host immune

159 uman IGF-1)/BP3 (binding peptide 3) improves lung growth and prevents PH in two antenatal models of B

160 any analyzed lung region.Conclusions: Cystic lung has greater normalized Vt when compared with noncys

161 ncreased each other's receptor expression on lung ILC2 in vivo and in vitro.

162 TSLPR and ST2 expression on lung ILC2 were measured by flow cytometry after treatmen

163 t organs including the heart, liver, kidney, lungs, immune system, gastro-intestinal system, skin as

164 VLP platform to study miR signature in human lungs in response to CI/EVR.

165 A shift of the fissures of both lungs in the basal direction was apparent for the older

166 ly promote T(H)2-cell differentiation in the lung, independent of the draining lymph nodes.

167 anges in neutrophil elastase activity during lung infection and to assess the efficacy of a protease

168 the Rapid Diagnostics in Categorizing Acute Lung Infections (RADICAL) study.

169 cal role in alveolar macrophage homeostasis, lung inflammation and immunological disease.

170 lone is necessary and sufficient to regulate lung inflammation but it has no direct antiviral activit

171 e of host IL-6 response in the regulation of lung inflammation during AA and the control of S. pneumo

172 from Cpn 60.1, named IRL201104, on allergic lung inflammation induced by ovalbumin (OVA) in mice and

173 Gprc5a-knockout (ko) mice are susceptible to lung inflammation, tumorigenesis and metastasis, which r

174 elper 2 (Th2) cytokines that promote AHR and lung inflammation.

175 potential to prevent and to treat the acute lung injury after SARS-CoV-2 infection, especially for t

176 Lung injury and development and PH were quantified at di

177 function, reduced myocardial damage, shock, lung injury and improved survival independent of pancrea

178 te passage cells to clonal density, to mimic lung injury in vivo, selects for rare subsets of HBECs t

179 physiological, histological, and biochemical lung injury markers.

180 both zebrafish tail injury and murine acute lung injury models of neutrophilic inflammation, overexp

181 errupting the POOR-get-POORer progression of lung injury relies on two principles: 1) open the lung t

182 This "ventilator-induced lung injury vortex" of the shrinking baby lung is oppose

183 The extent of lung injury was identified at 24 h following BOP by asse

184 After acute lung injury, they are preferentially localized in regene

185 -17 and miR-548b that are known mediators of lung injury.

186 ale BALB/c strain) with an LPS-induced acute lung injury.

187 %), and most (78.7%) have moderate or severe lung involvement on CT studies.

188 Results showed that lung IR increased the tissue iron content and lipid pero

189 ial virus (RSV) infection in mouse and human lung is associated with oxidative injury and pathogenic

190 ed lung injury vortex" of the shrinking baby lung is opposed by reactive, adaptive, and reparative pr

191 Consistently, NETs are present in necrotic lung lesions of TB patients responding poorly to antibio

192 ic solid-organ transplant recipients (heart, lung, liver, kidney, multiorgan) at The Hospital for Sic

193 Lung macrophages are important in mounting an inflammato

194 Patients with active hematologic or lung malignancies, peri-COVID-19 lymphopenia, or baselin

195 ov, NCT02154490, and all research related to Lung-MAP (S1400) is completed.

196 y to decrease sputum eosinophils and inhibit lung mast cells in asthma.

197 We sought to characterize the lung mechanical properties underlying these two asthma p

198 pecific gene changes in the mTORC1-activated lung mesenchyme and establishes the importance of the WN

199 eased tumor growth, reduced the incidence of lung metastasis and increased overall survival of mice w

200 ized drug delivery systems against malignant lung metastasis of breast cancer have been extensively s

201 portantly, inhibition of neutrophil-mediated lung metastasis via the sustained release of Zileuton.

202 reased tumor growth and weight and inhibited lung metastasis.

203 mmatory mediators of mammary engraftment and lung metastatic growth in triple-negative breast cancer

204 e revealed that, in critically ill patients, lung microbiota are altered and correlate with alveolar

205 nts and reduced the formation of spontaneous lung micrometastases by PDX tumors in mice.

206 Using lung microvascular endothelial and alveolar epithelial c

207 ood, brain, heart, intestine, kidney, liver, lung, muscle and spleen were determined on day 21.

208 otective mechanism in pulmonary arterial and lung MV (microvascular) endothelial cells in response to

209 E-cadherin expression persists in metastatic lung nodules and circulating tumor cells (CTCs) in two m

210 In addition, expression of lung nuclear-encoded genes changed specifically with mt-

211 We examined 7 lungs obtained during autopsy from patients who died fro

212 died from Covid-19 and compared them with 7 lungs obtained during autopsy from patients who died fro

213 cells and monocytes present in the blood and lung of COVID-19 patients with different clinical severi

214 Neutrophil recruitment in the lung of superinfected mice was decreased; however, mice

215 ter admission.Measurements and Main Results: Lungs of 91 critically ill patients were sampled using m

216 ectable viral genome or antigen was noted in lungs of animals in either vaccine group.

217 density of IMs was 36% to 56% greater in the lungs of cigarette smokers versus nonsmokers.Conclusions

218 profile of P. aeruginosa cells isolated from lungs of infected mice and examined the roles of upregul

219 P3K8 mRNA levels were found decreased in the lungs of IPF patients and of mice upon bleomycin-induced

220 prolong the residence time of rhDNase in the lungs of mice after pulmonary delivery while preserving

221 ed an increase in necrotic cell death in the lungs of superinfected mice compared to mice infected wi

222 itionally, CXCL1 and CXCL2 were decreased in lungs of superinfected mice compared with controls.

223 which dramatically increased toward term in lungs of WT fetuses, was markedly reduced in Src-1/-2(d/

224 Upon passive staining of mouse brain, lung or intestinal tissue surface with minute quantities

225 We created distal lung organoids with apical-out polarity to present ACE2

226 showed that expression of TOLLIP gene in the lung parenchyma is globally lower in IPF compared to con

227 asound, which can also be used to assess the lung parenchyma, to identify pleural fluid; CT scanning

228 Of 2294 MESA Lung participants without prevalent COPD, 98 (4.3%) had

229 ction and reduce lung viral loads and severe lung pathology.

230 counting method (SC) or 2-dimensional planar lung perfusion scintigraphy (PS).

231 Mouse lung pericytes were isolated and transfected with a miR-

232 e WNT signaling pathway in the mTORC1-driven lung phenotype.

233 o compare differences in performance between Lung-RADS and VRC.

234 single) lung recipients, and those with fewer than four (vs.

235 aracteristics of the respiratory system, and lung recruitment assessed by a CT scan in mechanically v

236 Potential for lung recruitment was assessed by the recently described

237 sequences of transcriptional programs during lung regeneration have remained elusive.

238 tory rate did not improve Vt of any analyzed lung region.Conclusions: Cystic lung has greater normali

239 poxic pulmonary vasoconstriction in infected lung regions, no studies have determined whether such ex

240 hat are prominent in epithelial cells in the lung, regulate expression of the gene.

241 ave focused on the adult lung, the perinatal lung remains unexplored.

242 m in many diseases besides cancer, including lung, renal, and neurodevelopmental disorders.

243 esponses to injury, and new methods to study lung repair and regeneration.

244 p arthroplasty, total knee arthroplasty, and lung resection were identified.

245 (14%) pancreaticoduodenectomy, 40,328 (14%) lung resection, 16,127 (6%) CABG and 10,602 (3%) esophag

246 ase in CTC attachment to ECs or Balb/C mouse lungs, respectively, compared to untreated conditions.

247 ered distribution of initiated tumors in the lung, resulting from loss of p107 or p130 Collectively,

248 Human emphysema lung samples exhibited reduced EC HIF-2alpha expression.

249 tomography images of IPNs from the National Lung Screening Trial, internally validated, and external

250 e Services Task Force (USPSTF) for annual CT lung screening were analysed for pulmonary nodules (PN)

251 The peripheral lung showed reduced ventilation and a greater response t

252 lectrical field stimulation in precision cut lung slices (PCLS) were assessed.

253 Here, we show that lung-specific loss of Kmt2d promotes lung tumorigenesis

254 ge, which was associated with suppression of lung-specific Th2 responses long after initial treatment

255 pathology and lower bacterial burdens in the lung, spleen, and liver.

256 Lung-, spleen- and liver-targeted SORT lipid nanoparticl

257 l blood biomarkers that inform about patient lung status and guide treatment.

258 s: Postnatal rhIGF-1/BP3 treatment preserved lung structure and prevented RVH in antenatal and postna

259 exudates in the alveolar spaces of Covid-19 lungs, supporting the notion that the macromolecule is i

260 roperties such as particle deposition in the lung, the large spatial gradients of chemical mixing sta

261 hough many studies have focused on the adult lung, the perinatal lung remains unexplored.

262 pressor cells recruited to the premetastatic lungs through complement C5a receptor 1 signaling.

263 ovirus-mediated C/EBPgamma expression in the lung tissue alleviates LPS-/IgG immune complexes-stimula

264 The hysteresis ratio was related to both lung tissue and gas recruitment (R = 0.266, p = 0.008, R

265 Its primary role is to protect lung tissue by inhibiting neutrophil elastase.

266 e and cell survival was observed in the EVLP lung tissue compared with lungs undergoing standard tran

267 egulation of FABP5 and ST2 expression in the lung tissue compared with normal diet (ND)-fed mice.

268 sease; and transcriptome-wide association in lung tissue revealed that high expression of the monocyt

269 The lipid composition of arteries in lung tissue samples from human PAH and control patients

270 nic variants; expression data from blood and lung tissue showed that the majority affect the expressi

271 tially stimulated macrophages, one to assess lung tissue-resident cells (TR-Mphi) and two for their p

272 es in IL-33, IL-4, IL-5, and IL-13 levels in lung tissue.

273 ecently showed decreased SIRT7 expression in lung tissues and fibroblasts from patients with pulmonar

274 In healthy lung tissues from humans and rats, Kv11.1 channels were

275 Using lung tissues from IPF and control subjects, we showed th

276 injury relies on two principles: 1) open the lung to minimize the presence of heterogeneity-induced s

277 meter, while CDH fetuses undergoing TO had a lung-to-body-weight ratio comparable to that of controls

278 patient travel distance was associated with lung transplant outcomes.

279 nificant cause of morbidity and mortality in lung transplant recipients (LTRs).

280 aneous coronary intervention; or heart/heart-lung transplant).

281 significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-savin

282 he anastomosis within the first 3 days after lung transplantation, with more numerous and complex lym

283 ney, 67 liver, 85 pancreas, 68 heart, and 43 lung TRRs.

284 These findings indicate that KMT2D is a lung tumor suppressor and that KMT2D deficiency confers

285 Lung tumor suppressor gene Gprc5a-knockout (ko) mice are

286 ow that lung-specific loss of Kmt2d promotes lung tumorigenesis in mice and upregulates pro-tumorigen

287 served in the EVLP lung tissue compared with lungs undergoing standard transplantation.

288 ependent manner that minimizes the number of lung units that close during each expiration so that the

289 smatch was elevated (median, 34% [32-45%] of lung units) and, in six out of seven patients, ventilate

290 c stresses, whereas RTN selectively controls lung ventilation and arterial Pco(2) stability.

291 ic RDV improve pulmonary function and reduce lung viral loads and severe lung pathology.

292 significantly larger volume of high-density lung volume (12.26 dl IQR 4.65 dl vs. 7.51 dl vs. IQR 5.

293 lower proportion of medium- and low-density lung volume compared to patients on the normal ward, but

294 tly associated with a 0.12-L decrease in the lung volume of exhaled air (95% confidence interval, -0.

295 Fibrosis in O3-exposed KKAy lungs was confirmed with immunohistochemistry, tissue hy

296 CG-disA-OE versus wild-type BCG and measured lung weights, pathology scores, and M.tb.

297 The lungs were studied with the use of seven-color immunohis

298 and reduced eosinophil recruitment into the lung, which was beneficial to the host in reducing aller

299 nia and strong inflammatory responses in the lungs with neutrophil infiltration and edema, further co

300 hibits a distinct immunologic profile in the lungs, with a depleted and exhausted CD4 and CD8 T-cell