ライフサイエンスコーパス: lung tissue

1 trast, an accumulation of these cells in the lung tissue.

2 chial brushes and cultured HBECs, but not in lung tissue.

3 es in IL-33, IL-4, IL-5, and IL-13 levels in lung tissue.

4 ecruitment and reduced fluid accumulation in lung tissue.

5 ogen does not grow in non-hAM cells of human lung tissue.

6 pment of treatments to repair and regenerate lung tissue.

7 ation with an increase in IL-1beta levels in lung tissue.

8 matrix, and static extraction in homogenized lung tissue.

9 scans or invasive procedures that sample the lung tissue.

10 sed abundance of these cells in OPA-affected lung tissue.

11 y lymphatic heterogeneity within and between lung tissue.

12 g to assess the function of human peripheral lung tissue.

13 alveolar macrophages (hAMs) in ex vivo human lung tissue.

14 wave ablation zone volumes in normal porcine lung tissue.

15 sed in both bronchoalveolar lavage fluid and lung tissue.

16 ions of NK cells in the bronchioalveolar and lung tissue.

17 6 messenger RNA (U41 and U57 transcripts) in lung tissue.

18 method and compared with staining in normal lung tissue.

19 ed a robust expression of FOXD3-AS1 in mouse lung tissue.

20 oduction of reactive oxygen species (ROS) in lung tissue.

21 l and the presence of carbon deposits within lung tissue.

22 cursors were detected in primary cultures of lung tissue.

23 ung injury with two-photon imaging of intact lung tissue.

24 ers by immunohistochemical assessment of IPF lung tissue.

25 lasma may be interrogated in lieu of BALF or lung tissue.

26 anhydrases, which were also expressed in LAM lung tissue.

27 ced EP4 mRNA expression in pulmonary ECs and lung tissue.

28 performed eQTL and co-expression analyses in lung tissue.

29 ical density of surfactant positive cells in lung tissue.

30 es, bone marrow-derived dendritic cells, and lung tissue.

31 primary AEC2 (pAEC2) isolated from resected lung tissue.

32 inhibition of the activation of NF-kappaB in lung tissue.

33 o the respiratory tract and invade airway or lung tissue.

34 ughout the basement membrane region of mouse lung tissue.

35 om perfusate solution and a homogenized lamb lung tissue.

36 cting skin, cardiovascular, and particularly lung tissue.

37 ype 2 cells/pneumocytes derived from primary lung tissue.

38 ations through effects on gene expression in lung tissue.

39 ulation and altered mechanical properties of lung tissue.

40 ulation of MHC-II on AT-II cells in inflamed lung tissue.

41 in human idiopathic pulmonary fibrosis (IPF) lung tissue.

42 cine may favor a partial recover of infected lung tissue.

43 ion at m/z 885.6 as a marker of PAH in human lung tissue.

44 nd secretory primed subsets in control adult lung tissue.

45 nd there are no reports on MIF expression in lung tissue.

46 v11.1 channel expression and function in the lung tissue.

47 mice and established receptor expression in lung tissues.

48 egaly and the bacterial burden in spleen and lung tissues.

49 ve adenocarcinomas and their adjacent normal lung tissues.

50 approach for fibroblast isolation from human lung tissues.

51 sis and glucose oxidation relative to benign lung tissues.

52 ibition of viral infection and growth in the lung tissues.

53 s and 19 metabolites (284 in total) in mouse lung tissues.

54 BRBP is reduced in LuADCs compared to normal lung tissues.

55 regs are rapidly mobilized into the inflamed lung tissues.

56 d autoimmunity that mainly targeted skin and lung tissues.

57 romotes wound repair in adipose, muscle, and lung tissues.

58 ofibroblast differentiation in vivo in mouse lung tissues.

59 s and were immunologically well tolerated by lung tissues.

60 , this pattern mirrored that observed in IPF lung tissues.

61 inhibit FcepsilonR1-activated mast cells in lung tissues.

62 n for asthma development in both thyroid and lung tissues.

63 hages as well as monocytic cells that survey lung tissues.

64 nt stromal cell types in tumors and adjacent lung tissues.

65 oring EGFR mutations and five tumor-adjacent lung tissues.

66 fecting the migration of ILC2s into inflamed lung tissues.

67 IL-1beta, IL-6, and IL-12p40 are produced in lung tissue after administration of TDM to mice.

68 In addition, OxPLs clearance from the lung tissue after LPS challenge was delayed in the aged

69 ovirus-mediated C/EBPgamma expression in the lung tissue alleviates LPS-/IgG immune complexes-stimula

70 ed that IR-induced ferroptotic cell death in lung tissue and ACSL4 were correlated with this process.

71 orrected ratio of (18)F-FDG concentration in lung tissue and blood plasma) might be an alternative to

72 NCTC 7466 by reducing the bacterial load in lung tissue and blood.

73 receptor (hFP-R) is widely expressed in the lung tissue and constitutes an attractive target for the

74 Lung tissue and endothelial cells from patients with PAH

75 TLR3 expression was reduced in PAH patient lung tissue and endothelial cells, and TLR3(-/-) mice ex

76 The hysteresis ratio was related to both lung tissue and gas recruitment (R = 0.266, p = 0.008, R

77 Explanted small bronchi isolated from human lung tissue and human airway smooth muscle cells were tr

78 Human postmortem lung tissue and human lung epithelial cell line BEAS-2B.

79 C-II colocalization was observed in inflamed lung tissue and IDLA cells of AT-II cellular origin.

80 ue for hAT2 cells derived from primary human lung tissue and investigate infection response to SARS-C

81 roteins including ferritin are higher in the lung tissue and lavage fluid of individuals with chronic

82 dy-state pharmacokinetic profiles in plasma, lung tissue and lung lesion homogenate were simulated fo

83 n, frequency, and characteristics of TCRs in lung tissue and matched blood from individuals infected

84 otic pathways.Methods: ER expression in male lung tissue and myofibroblasts from control subjects (n

85 senescence markers are detectable within IPF lung tissue and senescent cell deletion rejuvenates pulm

86 ific IgA-secreting B-cell frequencies in the lung tissue and serum IgA while reducing serum IgE conce

87 ent gene expression data set of COPD and IPF lung tissue and showed statistically significant overlap

88 e reduced the virus load in the tracheal and lung tissue and significantly reduced the clinical signs

89 ing cells in the airway epithelium of normal lung tissue and that from patients with chronic obstruct

90 case definitions, poor access to pathologic lung tissue and to specimens from fatal cases, poor diag

91 We collected blood, pancreas, kidney, and lung tissues and analyzed them by histology, immunofluor

92 activator, TEPP46, augmented PKM activity in lung tissues and attenuated airway eosinophils, mucus me

93 Lung tissues and blood samples were collected from rats

94 were notably overexpressed in all tested IPF lung tissues and fibroblast cells.

95 ecently showed decreased SIRT7 expression in lung tissues and fibroblasts from patients with pulmonar

96 s had increased Fn14 and TWEAK expression in lung tissues and increased serum soluble TWEAK concentra

97 Analysis of human lung tissues and primary human lung fibroblasts indicate

98 toxicity and reduces TcsL-induced damage to lung tissues and the lethality rate in mice.

99 ted lymphoid tissue, induced regeneration of lung tissue, and reverted airway fibrosis and systemic m

100 mmune parameters measured in the gut mucosa, lung tissue, and serum samples.

101 d by increased TrkB gene expression in human lung tissue, and SNPs in the NTRK2 [TrkB] and BDNF genes

102 ltration of IL-35-producing B cells into the lung tissue, and the elevated counts of IL-35-producing

103 ammation in bronchoalveolar lavage (BAL) and lung tissue, and total free IgE in serum samples were an

104 d TCR repertoire of peripheral blood, normal lung tissue, and tumor tissue from NSCLC patients.

105 neumoniae infection, have increased IL-22 in lung tissues, and sustain longer survival upon infection

106 ovascular niche as well as subsequent distal lung tissue architecture via Wnt signaling.

107 n was reduced in human and experimental COPD lung tissues as well as in primary human ATII cells from

108 1 via TGFbeta in myofibroblasts and fibrotic lung tissue, as well as its correlation with decreased p

109 nflux and IL-4, IL-5 and IL-13 production in lung tissue, as well as TH2 cell activation.

110 The primary outcome was lung tissue bacterial concentration.

111 s] cohorts) and between SNPs and expression (lung tissue, bronchial brushes, HBECs) was done using re

112 Lung tissue, bronchoalveolar fluid, and plasma were anal

113 ncreased the number of eosinophils in BM and lung tissue but failed to affect structural changes.

114 in Mycobacterium tuberculosis (Mtb)-infected lung tissue but is absent in areas of immunopathology.

115 r epithelial cells can be derived from human lung tissue but the quality of these cells is highly don

116 Its primary role is to protect lung tissue by inhibiting neutrophil elastase.

117 Lung tissue can robustly regenerate functional alveolar

118 Together these studies suggest that the lung tissue can serve as an important reservoir for HIV.

119 nia remains challenging because the infected lung tissue cannot usually be sampled for testing.

120 protease gene expression profiling in whole lung tissue, cathepsin K gene expression was 40-fold ove

121 Our supervised method for thin lung tissue classified NETs with sensitivity/specificity

122 It was assayed ex vivo in resected lung tissues collected from a dozen of patients.

123 (BAL) and increased collagen content in the lung tissue compared to saline controls.

124 e and cell survival was observed in the EVLP lung tissue compared with lungs undergoing standard tran

125 egulation of FABP5 and ST2 expression in the lung tissue compared with normal diet (ND)-fed mice.

126 approximately 75,000 human cells across all lung tissue compartments and circulating blood, combined

127 t the dissociation rate constant of DOX from lung tissue components is very rapid; therefore, the mas

128 Review of murine lung tissue confirmed a diagnosis of adenoma and early a

129 inished the ferroptotic damage in IR-injured lung tissue, consistent with the protective effect of AC

130 h coverage rate of HTNV in Apodemus agrarius lung tissues containing up to 10(3)-10(4) copies/muL of

131 on and intensive proinflammatory response in lung tissues contribute to high pathogenicity of MERS-Co

132 There was no effect of MCH on fetal plasma/lung tissue cortisol concentrations, nor genes regulatin

133 r study might thus suggest that high-density lung tissue could serve as a possible predictor of sever

134 36 on influenza virus replication in a human lung tissue culture model and observed strong inhibition

135 ATII cells in vitro and in three-dimensional lung tissue cultures ex vivo.

136 t percentage of nonventilated/hypoventilated lung tissue (cutoff was defined as 0.075 regional ventil

137 ve cytokine signaling frequently exacerbates lung tissue damage during respiratory viral infection.

138 quired for bacterial clearance, reduction of lung tissue damage, and host survival during KP35 pneumo

139 Severe lung tissue damage, with reduced numbers of ATP-binding

140 h HULIS has implications on human health via lung tissue damage; and its absorption character may add

141 e Tautomerase (DDT) and DDT-like (DDTL) in a lung tissue dataset with 1087 subjects and identified si

142 Levels of A20/TNFAIP3 expression in lung tissue demonstrated that HFD female mice express lo

143 This vector also transduces human lung tissue, demonstrating its potential for clinical tr

144 gly, inhibition of WNT-5A in vivo attenuated lung tissue destruction, improved lung function, and res

145 in blood, tonsil, synovial fluid, colon, and lung tissues did not express ST2, so ST2(+) Tregs were e

146 COPD lung tissue displayed significantly elevated CCR2 levels

147 (BLT) reconstitution method, in addition to lung tissue engraftment, giving altogether a realistic m

148 Ab can inhibit mast cell activation in human lung tissue ex vivo.

149 TRAP activity in murine macrophage and human lung tissue extracts.

150 ammatory cytokine expression in pancreas and lung tissues, fMLF peptide-induced oxidative burst in hu

151 tissue-resident memory T cells (Trm) in the lung tissue following influenza infection.

152 psy (TBLC) is a novel technique for sampling lung tissue for interstitial lung disease diagnosis.

153 epithelial cells (AEC-IIs) within autopsied lung tissue from a patient with A/H1N1/pdm09 pneumonia.

154 l heart failure patients and a validation in lung tissue from a representative mouse model were compl

155 utic surgical resection (n = 14) and healthy lung tissue from control subjects without tuberculosis (

156 e from patients with IPF (n=46) than that in lung tissue from controls (n=51).

157 Flow cytometric analysis of lung tissue from H2 R-deficient animals revealed increas

158 When comparing lung tissue from health and disease, human pulmonary lym

159 In lung tissue from idiopathic pulmonary fibrosis patients,

160 Histochemical studies of lung tissue from one fatality show sub-anatomical distri

161 with increased expression of AKAP13 mRNA in lung tissue from patients who had lung resection procedu

162 te the parenchymal architecture of unstained lung tissue from patients who succumbed to Covid-19.

163 P13 mRNA expression was 1.42-times higher in lung tissue from patients with IPF (n=46) than that in l

164 non-T(RM) cells present in tumor and normal lung tissue from patients with lung cancer revealed that

165 were assessed in parallel using fresh-frozen lung tissue from sibling rats of the same cages.

166 es, epithelial cells, or other cell types in lung tissue from subjects with pulmonary fibrosis compar

167 TRPV4 levels were measured in postmortem lung tissue from ventilated and nonventilated patients.

168 Autopsy lung tissue from ventilated patients showed decreased lu

169 ch for hantaviruses in RNAlater(R)-preserved lung tissues from 215 bats (order Chiroptera) representi

170 zing 461 lung adenocarcinomas and 156 normal lung tissues from 3 separate cohorts.

171 ing 5 (TXNDC5), is highly upregulated in the lung tissues from both patients with idiopathic pulmonar

172 human PAH.Methods: We used immunostaining of lung tissues from experimental PH models and patients wi

173 In healthy lung tissues from humans and rats, Kv11.1 channels were

174 he large pulmonary arteries (PAs) of healthy lung tissues from humans and rats.

175 Using lung tissues from IPF and control subjects, we showed th

176 Pancreata and lung tissues from mice were analyzed by histology, immun

177 resected cancerous and matched noncancerous lung tissues from nonsmall cell lung cancer (NSCLC) pati

178 miR-101 expression was determined in lung tissues from patients with IPF and mice with bleomy

179 Analysis of plasma and lung tissues from SEB-exposed mice treated with abatacep

180 sion profiling on a large sample of resected lung tissues from subjects with severe COPD.

181 CLC tissues, in contrast to the noncancerous lung tissues from the same patient, which showed lower m

182 ents, including 73 novel variants, influence lung tissue gene expression and implicate immune-related

183 e associated with less severe BHR and higher lung tissue gene expression.

184 because the majority of A/H1N1/pdm09 in the lung tissue harbored an aspartic acid-to-glycine substit

185 ary breast tumors, normal breast tissue, and lung tissue have similar protective effects on tumor cel

186 a and phages in the lungs and spleen, and 3) lung tissue histopathology.

187 Bovine lung tissue homogenate was selected as a surrogate matri

188 philia counts in bronchoalveolar lavages and lung tissue homogenates.

189 r experiments using mouse models and excised lung tissue identified contributors that drive a vicious

190 l RNA sequencing of neonatal human and mouse lung tissues, immunostaining, and FACS analysis to ident

191 lungs and bladder and inhibits DNA repair in lung tissues, implicate ECS as a lung and potential blad

192 m peripheral blood, spleen, bone marrow, and lung tissue in a mouse model infected with Mycobacterium

193 e expression by RNA in situ hybridization in lung tissue in all three tested subjects with HHV-6B(+)

194 ng blood and in the spleen, bone marrow, and lung tissue in BCG-infected mice, whereas anti-TB therap

195 female mice express lower levels of EpCAM in lung tissue in comparison with males and lean females.

196 anine and long-term adenoma formation in the lung tissues in A/J mice.

197 pithelium, olfactory bulb, frontal lobe, and lung tissues in cadavers from the city of Sao Paulo, SP,

198 Transcriptional and protein assays of lung tissue indicated p38(MAPK)-dependent activation of

199 o counteract elevated systemic inflammation, lung tissue inflammation, and iron overload in SCD.

200 ldren-namely complex surfactant dysfunction, lung tissue inflammation, loss of lung volume, increased

201 LPA1 is involved in pathways leading, after lung tissue injury, to pulmonary fibrosis instead of nor

202 d establishing a working diagnosis of IPF if lung tissue is not available.

203 In later stages, normal lung tissue is replaced by a large amount of young colla

204 heterogeneity, and the paucity of early ARDS lung tissue limit some applications of the rapidly evolv

205 d composition, previous knowledge of healthy lung tissue lipid composition is essential; however, the

206 This baseline knowledge of healthy lung tissue lipid composition will be extremely useful i

207 As fibrosis thickens, the lung tissue loses the ability to facilitate gas exchange

208 he expression of inflammatory markers in the lung tissue lysates using reverse transcription quantita

209 at a downstream level, this lineage provides lung tissue macrophages (interstitial macrophages and ti

210 This study examines CXCL13 production by lung tissue macrophages from patients with IPF and the s

211 ational regions calculated and normalized to lung tissue mass (normalized gas volume and normalized b

212 holesterol levels in irradiated cells and in lung tissue measured by a biochemical method and by fili

213 rmation for age-related diseases that affect lung tissue mechanics.

214 Cancerous and the paired non-cancerous lung tissue miRNAs display different pattern of 3'-termi

215 s virus infects and replicates in cotton rat lung tissue more efficiently than the wt virus and is le

216 Results: ERalpha expression increased in IPF lung tissue, myofibroblasts, or BLM mice.

217 (n = 34 tissues from 16 patients) and normal lung tissues (n = 9 tissues from 6 patients).

218 d eosinophils are transiently present in the lung tissue not only in pathology (allergic disease, par

219 Lung tissue obtained at autopsy from three deceased Covi

220 Lung tissue obtained from 13 non-CLAD patients served as

221 : We performed single-cell RNA sequencing on lung tissue obtained from eight transplant donors and ei

222 hil-dependent helminth larval killing in the lung tissue occurs.

223 action and mRNA microarray, respectively, on lung tissue of 30 patients (screening cohort) encompassi

224 E2) has shown vascular protective effects in lung tissue of brain death (BD) male rats.

225 pectroscopy (LC/MS-MS) on plasma, urine, and lung tissue of Hhip (+/-) heterozygotes and wild type (H

226 re with basal cells obtained from the distal lung tissue of IPF lungs.

227 we apply single-cell cloning technologies to lung tissue of patients with and without COPD.

228 To identify dysregulated miRNAs in lung tissue of patients with chronic obstructive pulmona

229 cterize the lipids ordinarily present in the lung tissue of seven cetacean species; and second, to be

230 but ACE2 expression has not been studied in lung tissue of subjects with diabetes.

231 L1 expression was significantly decreased in lung tissue of the silica-exposed animals compared to co

232 mesenchymal stem cells (LR-MSCs) and in the lung tissues of a pulmonary fibrosis model.

233 n and epithelial morphology were assessed in lung tissues of control and COPD patients.

234 d in macrophage-like inflammatory cells from lung tissues of patients with idiopathic PH.

235 gnature cytokines in splenic lymphocytes and lung tissue on IL-33 injection.

236 sitic worm infections, than macrophages from lung tissue or the peritoneal cavity.

237 tors in murine bronchoalveolar lavage fluid, lung tissue, or human nasal polyp tissue were analyzed b

238 s invasive, which allows imaging of the same lung tissue over a period of weeks.

239 d overexpressed in LAM compared with control lung tissue (P </= 0.0001).

240 erase, polypeptide 5 (B4GALT5) expression in lung tissue (P = 1.18 x 10(-17)).

241 In IPF lung tissue, pathological MPCs resided in the highly cel

242 th an increased Th2 response and exacerbated lung tissue pathology.

243 (BALF) macrophages and neutrophils and whole lung tissue proinflammatory IL-1beta mRNA expression but

244 l distributions of lipids and metabolites in lung tissues provides important molecular insights relat

245 of superoxide dismutase-2, thereby reducing lung tissue reactive oxidative species concentrations.

246 wed that the optimal cutoff value to predict lung tissue recruitment for the hysteresis ratio was 28%

247 H2O) needed to restore poorly and nonaerated lung tissue, reestablishing lung elastance and oxygenati

248 dependent upregulation of Notch4 receptor on lung tissue regulatory T (T(reg)) cells is necessary for

249 tially stimulated macrophages, one to assess lung tissue-resident cells (TR-Mphi) and two for their p

250 d with gene expression of HHIP and FAM13A in lung tissue, respectively; and were genome-wide signific

251 ortem specimens (blood, cerebrospinal fluid, lung tissue, respiratory tract swabs, and rectal swabs)

252 sease; and transcriptome-wide association in lung tissue revealed that high expression of the monocyt

253 by immunohistochemistry on paraffin-embedded lung tissue samples and quantified in alveolar and bronc

254 We conducted a retrospective study including lung tissue samples from 24 patients with pulmonary LCDD

255 itis with B-cell follicles and emphysema, in lung tissue samples from control subjects, and in skin,

256 The lipid composition of arteries in lung tissue samples from human PAH and control patients

257 ata resources, and examined expression using lung tissue samples from patients with IPF and controls.

258 Human microbiota were evaluated in lung tissue samples from workers with respiratory sympto

259 trait locus (eQTL) analysis in 1,425 normal lung tissue samples highlights RNASET2, SECISBP2L and NR

260 omposition was found between MWF samples and lung tissue samples of case workers compared with contro

261 studied ACE2 mRNA and protein expression in lung tissue samples of subjects with and without diabete

262 Using the gene expression profiles of 1,038 lung tissue samples, we performed a weighted gene correl

263 analyses of viral nucleoprotein staining of lung tissue sections and dissociated lung cells.

264 Our unsupervised method for thin lung tissue sections in murine fungal pneumonia achieved

265 revealed twelve times higher iron levels in lung tissue sections of COPD patients when compared to h

266 and relatively quantify iron accumulation in lung tissue sections of healthy donors versus severe COP

267 SARS-CoV-2-infected lung tissues show a massively upregulated innate immune

268 The amount of high-density lung tissue showed a significant association with severe

269 Histological analysis of lung tissue showed significant pathology associated with

270 Furthermore, an in situ examination of lung tissue showed that stromal fibroblasts expressed ca

271 nic variants; expression data from blood and lung tissue showed that the majority affect the expressi

272 u hybridization of sarcoidosis granulomatous lung tissues showed abundance of HIF-1alpha in the cente

273 d functional enrichment of COPD risk loci in lung tissue, smooth muscle, and several lung cell types.

274 s and viral quantification were performed on lung-tissue specimens.

275 tory ventilation may not be appropriate when lung tissue stretch occurs heterogeneously and/or rapidl

276 ntly lower bacterial burden in both BALF and lung tissue than did Spp1(-/-) mice.

277 l recruitment, and a lower bacterial load in lung tissue than mice infected with wild-type P. aerugin

278 fluidic modelling successfully shows that in lung tissue the fluid derived from the blood vessels dra

279 ation by promoting eosinophil clearance from lung tissue through chemotaxis, independent of SP-A2 Q22

280 Critically, we show that type 2 priming of lung tissue through increased mucin production inhibits

281 xide synthase and endothelin was assessed in lung tissue to determine differences in pulmonary vascul

282 study the transcriptional response of ovine lung tissue to infection by JSRV.

283 In situ hybridization was done on normal lung tissue to localize miR-200b-3p in airway epithelium

284 ducted a multiomics analysis of nonmalignant lung tissue to quantify the transcriptome, translatome,

285 Exposure of lung tissues to cigarette smoke is a major cause of huma

286 At 138 days, gene expression in fetal lung tissue was determined by quantitative RT-PCR.

287 Lung tissue was explanted after the animals were killed,

288 tral confocal microscopy of human and murine lung tissue was performed to localize Syk expression.

289 MicroRNA expression profiling of the lung tissue was performed using next-generation sequenci

290 of lipid coverage in nano-DESI MSI of mouse lung tissues was compared to liquid chromatography tande

291 Using an unbiased proteomics screen in lung tissue, we identified the membrane protein caveolin

292 or DOX extracted from buffer, perfusate, and lung tissue were 40, 100, and 3700 mug L(-1), respective

293 aerated, normally aerated, and hyperaerated lung tissue were assessed at low (5 cmH2O) and high (45

294 ells in the bronchoalveolar lavage fluid and lung tissue were assessed.

295 Placentas and lung tissue were collected at birth for morphometric and

296 urements in bronchoalveolar lavage fluid and lung tissue were followed by in vitro T(H) 2 differentia

297 0.5-2 mm) from macroscopically healthy human lung tissue were obtained from 48 patients and mounted i

298 Only lung tissues were subject to transmission electron micro

299 Here, we show that implantation of human lung tissue, which contains up to 40 cell types, includi

300 ckade prevented eosinophil infiltration into lung tissue without affecting circulating eosinophils, d