ライフサイエンスコーパス: lung volume

1 pinal motor neurons to muscles that regulate lung volume.

2 t in refining strategies to identify optimal lung volume.

3 mechanical ventilation at low end-expiratory lung volume.

4 arge tidal volumes and normal end-expiratory lung volume.

5 large tidal volume at normal end-expiratory lung volume.

6 rred on restoration of normal end-expiratory lung volume.

7 idal volume (7 mL .kg) at low end-expiratory lung volume.

8 veolar depth, and number of alveoli per unit lung volume.

9 milar over most of the lung, irrespective of lung volume.

10 hest and abdomen to assess global changes in lung volume.

11 sure-volume curve in predicting steady-state lung volume.

12 emodeling as the diaphragm adapts to reduced lung volume.

13 truct an algorithm for calculating predicted lung volume.

14 Oxygenation and end-expiratory lung volume.

15 l muscle activities act to maintain absolute lung volume.

16 ay pressure and a maintained/raised absolute lung volume.

17 moidal function of P(aw) and tau varied with lung volume.

18 , unmatched and matched defects by the total lung volume.

19 odel included, and the other controlled for, lung volume.

20 n maps of (1)H signal change between the two lung volumes.

21 tood, but may be related to breathing at low lung volumes.

22 truction, airway inflammation, and increased lung volumes.

23 o achieve a plateau pressure of 30 cm H(2)O) lung volumes.

24 peated, noninvasive measurements of regional lung volumes.

25 nd emphysema may have artificially preserved lung volumes.

26 ribution of pulmonary perfusion at different lung volumes.

27 Society guidelines using both spirometry and lung volumes.

28 -3 concentrations were associated with lower lung volumes (1.4% decrease in percentage of predicted F

29 expiratory pressure increased end-expiratory lung volume (+119% [p < .001] at 22 mm Hg intra-abdomina

30 significantly larger volume of high-density lung volume (12.26 dl IQR 4.65 dl vs. 7.51 dl vs. IQR 5.

31 ted in 24 healthy never-smokers across three lung volumes (20%, 60%, and 100% VC) on the basis of the

32 +/- 2%; p = 0.004) and decreased nonaerated lung volume (23% +/- 6% vs 38% +/- 5%; p = 0.033) in the

33 ry pressure further increased end-expiratory lung volume (+233% [p < .001] at 22 mm Hg intra-abdomina

34 onstriction produced elevated end-expiratory lung volume (279 +/- 62 ml); in a control study, end-exp

35 recruitment maneuver restored end-expiratory lung volume (30.4 +/- 9.1 mL/kg ideal body weight) and o

36 They were also associated with increases in lung volume (501 +/- 93 mL; P < .001 vs basal value) and

37 ersite agreement showed biases of 612 mL for lung volume, -60.7 mL for ventilation defect volume, 2.9

38 ecruited with a relatively small area (20 mL lung volume, 798 +/- 797 microm2) and progressively incr

39 atomic locations divided by the cube root of lung volume (airway to lung ratio).

40 resistance in extra-alveolar vessels at low lung volumes although other mechanisms have been propose

41 restoration of physiological end-expiratory lung volume and after prolonged mechanical ventilation w

42 ratory capacity, compliance, non-parenchymal lung volume and alveolarization, were increased in both

43 Response variables based on lung volume and anatomic position were assessed with mul

44 A distinct bell-shaped relationship between lung volume and carbon dioxide, minute ventilation, and

45 cluding less inspiratory effort and improved lung volume and compliance.

46 jury progression and improved lung function (lung volume and compliance; P < 0.05 compared with untre

47 examined relationships between steady-state lung volume and cumulative cyclic recruitment/derecruitm

48 In addition, there is a fall in total lung volume and forced expiratory volume at 100 ms.

49 roup failed to increase peak end-inspiratory lung volume and had a significantly smaller increase in

50 Incorporation of lung volume and hemodynamic and oxygenation variables ma

51 is associated with changes in end-expiratory lung volume and increased intrathoracic pressure, eventu

52 tric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung dis

53 ere: 1) to describe the relationship between lung volume and lung function parameters during mapping

54 an understanding of the relationship between lung volume and lung mechanics may help clinicians bette

55 ominal hypertension decreased end-expiratory lung volume and PaO2 (-49% [p < .001] and -8% [p < .05],

56 sure significantly increased the end-expired lung volume and PaO2 but impaired ventricular preload an

57 elease phase, which decreases end-expiratory lung volume and potentiates derecruitment).

58 rial burden predicted the rate of decline in lung volume and risk of death and associated independent

59 cted on the basis of expected end-expiratory lung volume and static compliance of the respiratory sys

60 To quantify the MRI T2 high-signal-intensity lung volume and T2-weighted volume-intensity product (VI

61 Its expiratory activity seems to preserve lung volume and to protect against lung collapse.

62 h a restrictive pattern, including decreased lung volumes and altered gas exchange.

63 ges were analyzed for total, air, and tissue lung volumes and axial and vertical aeration and perfusi

64 ions in lung physiology, including increased lung volumes and decreased tissue resistance.

65 potassium intakes were associated with lower lung volumes and flows.

66 Endobronchial valve placement can improve lung volumes and gas transfer in patients with chronic o

67 orn and raised at high altitudes have larger lung volumes and greater pulmonary diffusion capacity co

68 zed by interstitial fibrosis with decreasing lung volumes and hypoxemic respiratory failure.

69 Elevated lung volumes and increased pleural pressures associated

70 tory pressure were both necessary to improve lung volumes and the elastic properties of the lungs, le

71 re time product, and we estimated changes in lung volumes and ventilation homogeneity by electrical i

72 for carbon monoxide (DLCO) and nitric oxide, lung volume, and cardiac output by a rebreathing techniq

73 ratory control, low arousal threshold, small lung volume, and dysfunctional upper airway dilator musc

74 replaced hyperinflated lung, reduced overall lung volume, and improved respiratory function safely an

75 m underwater weighing with measured residual lung volume, and total body water from traditional BIS.

76 spirometry (n = 1,389), skin prick testing, lung volumes, and diffusing capacity measurements.

77 ormat in test-specific units for spirometry, lung volumes, and diffusing capacity that can be assembl

78 Objectives: PFTs (spirometry, lung volumes, and diffusion capacity for carbon monoxide

79 of between-group differences in spirometry, lung volumes, and left ventricular ejection fraction, pa

80 s IgE, increased respiratory symptoms, lower lung volumes, and worse asthma quality of life.

81 We measured end-expiratory lung volume, arterial oxygen levels, respiratory mechani

82 ung density at 15th percentile (adjusted for lung volume) as a measure of emphysema and percentage of

83 ique, with all measurements limited to tidal lung volume, as well as using inspiratory rather than ex

84 eflation pressure--volume (PV) curves from a lung volume at 30 cm H(2)O (V(30)) to FRC.

85 ace tension within the alveolus, maintaining lung volume at end expiration.

86 g values for plethysmographic assessments of lung volume at functional residual capacity (FRC) in inf

87 ssociated with a reduction in end-expiratory lung volume at peak exercise from 7.6 (1.6) to 7.2 (1.7)

88 Results Left and right lung volumes at end inspiration and end expiration incre

89 aths and mechanical ventilation at different lung volumes between functional residual capacity (FRC)

90 sure led to a preservation of end-expiratory lung volume, but did not improve arterial oxygen tension

91 te the mechanical strain at wearing sites to lung volume by measuring the local circumference changes

92 h eupneic tidal volume at low end-expiratory lung volume causes plasma membrane disruptions; and 2) t

93 Regional specific lung volume change (sVol), defined as the regional tidal

94 review papers dealing with the mechanism of lung volume change at the alveolar level and the role of

95 erated without complications, and it reduced lung volumes (change in total lung capacity -16%; change

96 We measured lung volume changes (deltaV(L)[t]) via respiratory induc

97 ay allow clinicians to more directly monitor lung volume changes during HFOV and use the lowest possi

98 del, EIT was shown to be capable of tracking lung volume changes during high-frequency oscillatory ve

99 This study shows that cross-sectional lung volume changes measured by electrical impedance tom

100 irth weight 1,027 +/- 514 g), end-expiratory lung volume changes measured by electrical impedance tom

101 y aimed to compare cross-sectional and whole lung volume changes using electrical impedance tomograph

102 End-expiratory lung volume changes were assessed by mapping the inflati

103 Cross-sectional and whole lung volume changes were continuously and simultaneously

104 inflation and ventilation with corresponding lung volume changes, emphasizing the need for tight cont

105 lower proportion of medium- and low-density lung volume compared to patients on the normal ward, but

106 decreases in DL(CO), and to a lesser extent lung volumes, correlated significantly with decreases in

107 dal loops and by computed tomography-derived lung volume data.

108 to 15 cm H2O did not prevent end-expiratory lung volume decline caused by intra-abdominal hypertensi

109 ra-abdominal pressure-induced end-expiratory lung volume decline in healthy lungs.

110 01) to prevent flow limitation, with a final lung volume decrease of 567 +/- 78 ml.

111 pressure titration increased end-expiratory lung volumes (Delta11 +/- 7 mL/kg; p < 0.01) and oxygena

112 and oxygenation variables may guide optimum lung volume determination during high-frequency ventilat

113 ificant or marginally significant decline in lung volume, diffusing capacity for carbon monoxide, and

114 H, and at 3 and 9 weeks after BLVR, included lung volumes, diffusing capacity (DL(CO)), pressure-volu

115 ation increased by decreasing end-expiratory lung volume during spontaneous breathing.

116 The ability of RIP to detect optimal lung volume during the weaning of mean airway pressure m

117 Previous studies have demonstrated that lung volume during wakefulness influences upper airway s

118 rived thoracic volumes correlated with known lung volumes during supersyringe (r(2) =.78, p <.00001).

119 seases is due to an exaggerated reduction in lung volumes during supine sleep, a compromised physiolo

120 y effort, minute ventilation, end-expiratory lung volume, dynamic compliance, and ventilation homogen

121 la: see text]co2 and its impact on operating lung volumes, dyspnea, and exercise tolerance in these p

122 The fraction of the total lung volume encompassed within the GV gaze volume s, the

123 er of published series to improve expiratory lung volumes, exercise capacity, and subjective well bei

124 Spirometry, lung volumes, exhaled nitric oxide levels, and systemic

125 and appeared to reduce emphysema-associated lung volume expansion in mice exposed to cigarette smoke

126 e relative lung volume-that is, the observed lung volume expressed as a percentage of the predicted l

127 volume was calculated as the observed total lung volume expressed as a percentage of the total lung

128 h eupneic tidal volume at low end-expiratory lung volume followed or not by the restoration of physio

129 linear regression (adjusted for pack-years, lung volume), followed by metaanalysis.

130 The ventilation defect to total lung volume fraction ranged from 0.1% to 11.6%.

131 osed individuals with ILA have reductions in lung volume, functional limitations, increased pulmonary

132 oved oxygenation, compliance, end-expiratory lung volume, functional residual capacity, and deadspace

133 Dysanapsis was associated with greater lung volumes (FVC, vital capacity, and total lung capaci

134 but statistically significant reductions in lung volume growth in children of elementary-school age.

135 demonstrate that relatively small changes in lung volume have an important effect on the upper airway

136 Regional differences in lung volume have been described in adults with acute res

137 espiratory inductive plethysmography-derived lung volume, high continuous distending pressure had adv

138 ned was: 17% (four of 24) for an ipsilateral lung volume (ILV) receiving 20 Gy or higher (ILV, 20 Gy)

139 Electrical impedance tomography measures lung volume in a cross-sectional slice of the lung.

140 ents may provide a simple method to optimize lung volume in a surfactant-deficient patient during hig

141 nd strategies for recruiting and maintaining lung volume in acute lung injury, we examined relationsh

142 Within London's LEZ, a smaller lung volume in children was associated with higher annua

143 We therefore hypothesized that residual lung volume in COPD would be associated with greater LV

144 The predicted lung volume in fetuses of a wide range of gestational ag

145 ARDS (14 +/- 5, 18 +/- 8, and 23 +/- 10% of lung volume in mild, moderate, and severe ARDS; P < 0.00

146 ur complex traits: height, forced expiratory lung volume in one second, general cognitive ability and

147 fusion (expressed as ml min(1) g(1)) between lung volumes in the gravitationally intermediate (RV = 8

148 ative extrathoracic pressure yielded a final lung volume increase of 421 +/- 36 ml above the initial

149 and P = 0.23, respectively); end-expiratory lung volume increased (P < 0.001), and tidal volume did

150 In health, peak Vt and end-inspiratory lung volume increased significantly with DS.

151 reversed into a caudal and inward motion as lung volume increased.

152 sfunction, lung tissue inflammation, loss of lung volume, increased shunt, and diffuse alveolar damag

153 Lung weight index (LWI), lung volume index (LVI), and alveolar cell proliferation

154 muscle force, to a greater extent with lower lung volume, indicating a diaphragmatic electromechanica

155 + approximate expiratory reserve volume, and lung volume-induced suppression of mean arterial pressur

156 Therefore, knowledge of lung volume is important for safe patient management.

157 MR imaging lung volumetry in which relative lung volume is used to quantify fetal pulmonary hypoplas

158 Improvement in operating lung volumes is the principal change seen as a chronic o

159 suggest that the adult lung did not increase lung volume later in life by expansion of an existing nu

160 The emphysema index of percentage upper lung volume less than -950 HU had the strongest associat

161 d change in relative DeltaZ representing the lung-volume loss was -9.8 (-3.0 mL/kg) during the first

162 mechanical ventilation at low end-expiratory lung volume, mainly at the bronchiolar level.

163 1) z-scores 1.12 vs -2.37; P < .05), greater lung volumes (mean % of predicted TLC 134.8% vs 109.6%;

164 ng the recruitment procedure, end-expiratory lung volume measured by respiratory inductive plethysmog

165 rs demonstrated excellent agreement in total lung volume measurements at MR imaging, with an intracla

166 pulmonary blood flow as evidenced by reduced lung volume measurements using respiratory inductive ple

167 Differences in total lung volume measurements were less than 1%.

168 sure; 63 subjects underwent UWW and residual lung volume measurements.

169 ack-years, CT model, milliamperes, and total lung volume.Measurements and Main Results: MESA Lung and

170 exhibit periodic increases in end-expiratory lung volume, mediated by changes in breath components, p

171 asively between 7 and 21 years, during which lung volume nearly quadruples.

172 ing techniques that have been used to assess lung volume noninvasively.

173 entilation and has the potential to quantify lung volumes noninvasively.

174 m)Tc-macroaggregated albumin to the anatomic lung volume obtained by small-animal CT.

175 Lung function decline over time, lung volume occupied by cysts (cyst score), and lung tis

176 tly associated with a 0.12-L decrease in the lung volume of exhaled air (95% confidence interval, -0.

177 re acquired during the same breath hold at a lung volume of functional residual capacity plus 1 L.

178 roved (p < 0.001 vs no-Sigh), end-expiratory lung volume of nondependent and dependent regions increa

179 erial blood gases, changes in end-expiratory lung volume of nondependent and dependent regions, tidal

180 ed a significant decrease in body weight and lung volume of smoke-exposed embryos.

181 the following equation for predicting fetal lung volume on the basis of independent biometric indexe

182 We sought to determine the influence of lung volume on the level of continuous positive airway p

183 logies, comorbidities, effects of obesity on lung volume or adipokines.

184 nary hyperinflation, as measured by residual lung volume or residual lung volume to total lung capaci

185 tude was a significant contributor for total lung volume (P = 0.02), air volume (P = 0.03), and tissu

186 f Zone 4 behaviour was not different between lung volumes (P = 0.23).

187 survivor patients (20 +/- 9 vs. 17 +/- 7% of lung volume; P = 0.01) and were the only CT scan variabl

188 antly improved lung function (compliance and lung volumes; p < 0.05) of TGF-beta adenovirus treated m

189 olume expressed as a percentage of the total lung volume predicted from fetal size.

190 macroglossia, bulbar manifestations, or low lung volumes, predispose patients to the development of

191 ation exhibit fluctuations in end-expiratory lung volume, primarily because of alterations in tidal v

192 End-expiratory lung volume progressively increased during the initial r

193 differentiation correlated with IPF patient lung volumes (r = 0.44, p < 0.03).

194 anged throughout, indicating that changes in lung volume rather than airflow resistance predominated.

195 improves exercise performance by increasing lung volume rather than changing expiratory flow.

196 asured functional residual capacity-to-total lung volume ratio.

197 parameters including V15, V20, V30 (percent lung volume receiving > or = 15, > or = 20, and > or = 3

198 e reduction surgery (LVRS) and bronchoscopic lung volume reduction (bLVR) are palliative treatments a

199 Bronchoscopic lung volume reduction (BLVR), a minimally invasive proce

200 ress the various techniques of bronchoscopic lung volume reduction (BLVR).

201 Lung volume reduction (LVR) is an effective therapy for

202 lation and select candidates for valve-based lung volume reduction (LVR) therapy.

203 aim to summarise clinical trial evidence on lung volume reduction and provide guidance on patient se

204 assessed the clinical benefits and safety of lung volume reduction coils (LVRCs) for the treatment of

205 bronchodilators but increased after surgical lung volume reduction compared with medical therapy.

206 Following lung volume reduction from any of the interventions in p

207 There were two deaths in the bronchoscopic lung volume reduction group and one control patient was

208 In the bronchoscopic lung volume reduction group, FEV1 increased by a median

209 ched MEDLINE on Sept 29, 2016, for trials of lung volume reduction in patients with emphysema, and we

210 e analyses, our results provide support that lung volume reduction in patients with severe emphysema

211 included 20 randomised controlled trials of lung volume reduction involving 2794 participants with e

212 Lung volume reduction of emphysematous lobes results in

213 Lung volume reduction procedures in the treatment of sev

214 Lung volume reduction surgery (LVRS) and bronchoscopic l

215 25 patients with severe emphysema undergoing lung volume reduction surgery (LVRS) and correlated thei

216 Lung volume reduction surgery (LVRS) as a bridge to lung

217 Lung volume reduction surgery (LVRS) is a treatment opti

218 Lung volume reduction surgery (LVRS) is associated with

219 ve diaphragm stretch occurring acutely after lung volume reduction surgery (LVRS) results in fiber in

220 Lung volume reduction surgery (LVRS), the removal of dam

221 hods used in the care of patients undergoing lung volume reduction surgery (LVRS).

222 ortant determinant of increased FEV(1) after lung volume reduction surgery (LVRS).

223 ratively in 37 patients undergoing bilateral lung volume reduction surgery (LVRS).

224 study led to a decrease in the acceptance of lung volume reduction surgery as a therapy.

225 h asthma, heavy smokers, patients undergoing lung volume reduction surgery for severe emphysema, and

226 Lung volume reduction surgery improves survival in selec

227 intravenous anesthesia may be beneficial in lung volume reduction surgery, lung transplantation and

228 Lung volume reduction surgery, where 20-30% of lung is r

229 nd lesser improvement in lung function after lung volume reduction surgery.

230 ged as an important predictor of response to lung volume reduction surgery.

231 could have benefits that are comparable with lung volume reduction surgery.

232 are needed that compare valve placement with lung volume reduction surgery.

233 Lung volume reduction using nitinol coils is a bronchosc

234 ssion, which we use to track the response to lung volume reduction via LVRS and bLVR.

235 nhaled bronchodilator treatment and surgical lung volume reduction were analyzed to evaluate the resp

236 ve unilateral lobar occlusion (bronchoscopic lung volume reduction) or a bronchoscopy with sham valve

237 stimulated a search for novel approaches to lung volume reduction.

238 lying emphysema progression before and after lung volume reduction.

239 Lung-volume reduction can be achieved with unilateral br

240 Airway bypass is a bronchoscopic lung-volume reduction procedure for emphysema whereby tr

241 Bronchoscopic lung-volume reduction with the use of one-way endobronch

242 undergo, lung transplantation, lobectomy, or lung volume-reduction surgery, or had selective IgA defi

243 e excluded, the cost-effectiveness ratio for lung-volume-reduction surgery as compared with medical t

244 Lung-volume-reduction surgery has been proposed as a pal

245 Overall, lung-volume-reduction surgery increases the chance of im

246 and benefits over three years of follow-up, lung-volume-reduction surgery is costly relative to medi

247 17 medical centers were randomly assigned to lung-volume-reduction surgery or continued medical treat

248 tation and were randomly assigned to undergo lung-volume-reduction surgery or to receive continued me

249 Trial, a randomized clinical trial comparing lung-volume-reduction surgery with medical therapy for s

250 ne exercise capacity are poor candidates for lung-volume-reduction surgery, because of increased mort

251 dependent lung is unlikely to be a result of lung volume related increases in resistance in extra-alv

252 aged with a 1.5-T whole-body MR unit at four lung volumes (residual volume [ RV residual volume ], fu

253 Lung volume (respiratory inductive plethysmography), oxy

254 fusion in patients with acute lung injury on lung volume, respiratory mechanics, gas exchange, lung r

255 titration was found to significantly improve lung volumes, respiratory system elastance, and oxygenat

256 ion (r = 0.62, P = .02) with the fraction of lung volume searched.

257 ory cytokines, and pulmonary function (total lung volume, static lung compliance, tissue damping, and

258 n the upstream segment of the airways at all lung volumes studied compared to HFEV(1) .

259 ending on ventilatory state (high versus low lung volume), suggesting state-dependent changes in comp

260 Finally, despite normal lung volume, Tgfbi-null lungs displayed diminished elast

261 50.7 +/- 14.0% higher at highest increase in lung volume than during preceding apnea (p < 0.05).

262 African-American children have lower lung volumes than White children.

263 (isovolumetric V max at intermediate to low lung volumes) than in FVC or FEV1.

264 The relative lung volume-that is, the observed lung volume expressed

265 Total lung volume (TLV) was measured by using planimetry on si

266 or = 18 Gy and < or = 10% of the ipsilateral lung volume to receive > or = 20 Gy.

267 y measure the contribution of that saturated lung volume to the gas transport capacity of the entire

268 measured by residual lung volume or residual lung volume to total lung capacity ratio, is associated

269 ed expiratory flow volume curves from raised lung volumes to assess airway function among infants wit

270 = 0.0085), and lung clearance index based on lung volume turnover required to reach 2.5% of starting

271 Findings imply insufficient ventilation/lung volume unit and insinuate a powerful marker for est

272 In the fetuses with normal chests, relative lung volume varied between 51% and 134%.

273 fetuses with pulmonary hypoplasia, relative lung volume varied between 6% and 70%.

274 Lung volume, ventilation defect volume, ventilated volum

275 Relative lung volume was calculated as the observed total lung vo

276 Lung volume was decreased by lowering end-expiratory air

277 At 16.5 dpc, the reduction in lung volume was due to loss of lung mesenchymal tissue c

278 oxel in the CT scan and after correcting for lung volume was expressed as the density at lowest 15th

279 ient with lung contusion of more than 30% of lung volume was followed without requiring further treat

280 The ICC for lung volume was greater at site B (0.83-0.86) than at si

281 ltivariate regression analysis, high-density lung volume was identified as a significant predictor of

282 When lung volume was increased by 1,035 +/- 22 ml, the CPAP l

283 - 62 ml); in a control study, end-expiratory lung volume was increased equally in the absence of bron

284 Residual lung volume was independently associated with greater LV

285 d entirely based on visual information while lung volume was not.

286 Conversely, when lung volume was reduced by 732 +/- 74 ml (n = 8), the CP

287 e expressed as a percentage of the predicted lung volume-was then calculated in fetuses with pulmonar

288 intercept length, alveolar surface area, and lung volume were similar between both genotypes.

289 uated at our referral clinic, the DL(CO) and lung volumes were decreased in approximately three-quart

290 Lung volumes were measured by spirometry and plethysmogr

291 Lung volumes were measured in 32 healthy infants (age, 4

292 Significant differences in ADCs between lung volumes were observed for all inflation levels (20%

293 emphasizing the need for tight control over lung volume when performing hyperpolarized helium 3 ((3)

294 were effective at increasing end-expiratory lung volumes while decreasing end-inspiratory transpulmo

295 cic insufficiency syndrome, especially right lung volume with 22.9% and 26.3% volume increase at end

296 as a measure of emphysema and percentage of lung volume with attenuation less than -856 HU at expira

297 eas were defined as the percentage of imaged lung volume with attenuation values between -600 and -25

298 sis to assess air trapping, airway size, and lung volume with inspiratory and expiratory X-ray comput

299 6 +/- 2.9 cm H2O) were associated with lower lung volumes, worse elastic properties of the lung, and

300 ypothesized that changes in both airflow and lung volumes would occur during an exacerbation, but tha