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2 hether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for la
3 lomic analysis of serum and whole-blood from luteinizing/follicle-stimulating (LH/FSH)-secreting (n =
4 sive apoptotic staining in unruptured poorly luteinized follicles, consistent with dramatic reduction
5 ol <184 pmol/l (50 pg/ml), FSH <10 IU/l, and luteinizing hormone <10 IU/l, was significantly more pre
7 tein-coupled receptors (GPCRs), activated by luteinizing hormone (hLH) and essentially involved in th
10 s thought to be indirectly controlled by the luteinizing hormone (LH) acting through the LH/choriogon
12 Meiosis in mammalian oocytes is paused until luteinizing hormone (LH) activates receptors in the mura
15 with consequent diminished levels of plasma luteinizing hormone (LH) and correspondingly attenuated
16 esis and secretion of gonadotropic hormones, luteinizing hormone (LH) and follicle stimulating hormon
17 osynthesis and release of the gonadotropins, luteinizing hormone (LH) and follicle stimulating hormon
19 ith gonadotropic endocrine cells [expressing luteinizing hormone (LH) and follicle-stimulating hormon
20 close to follicle-stimulating hormone (FSH), luteinizing hormone (LH) and growth hormone (GH) cells.
21 ve" group (21%-23%), characterized by higher luteinizing hormone (LH) and sex hormone binding globuli
22 n, serum follicle stimulating hormone (FSH), luteinizing hormone (LH) and testosterone levels or test
24 of gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) are pivotal events in female re
26 oma cells were treated with the gonadotropin luteinizing hormone (LH) at concentrations equivalent to
28 validate AutoDecon for application to serum luteinizing hormone (LH) concentration time series using
30 (GNRH)-stimulated synthesis and secretion of luteinizing hormone (LH) from the pituitary gonadotroph.
31 ating follicle-stimulating hormone (FSH) and luteinizing hormone (LH) gene expression in the pituitar
32 inhibited the kisspeptin-induced release of luteinizing hormone (LH) in rats and mice and blocked th
33 bone age versus the baseline measurement of luteinizing hormone (LH) in serum, used as the reference
35 and then augments (positive feedback) serum luteinizing hormone (LH) increased Kiss1 mRNA density an
40 along with minimal repression of circulating luteinizing hormone (LH) levels and no change in the lip
42 etion of GnRH is also reduced as basal serum luteinizing hormone (LH) levels were significantly lower
43 he fabrication of a nanosensor for detecting luteinizing hormone (LH) of sheep using a gold nanoparti
46 Adult obesity is associated with blunted luteinizing hormone (LH) pulse amplitude that is partial
47 fertility, is associated with an increase in luteinizing hormone (LH) pulse frequency, implicating ab
49 r cells in that they were 3betaHSD-negative, luteinizing hormone (LH) receptor (LHR)-negative, and pl
51 licular development, including expression of luteinizing hormone (LH) receptor by the granulosa cells
53 l mechanisms play a major role in regulating luteinizing hormone (LH) receptor mRNA expression in the
54 eral motions of individual FLAG-tagged human luteinizing hormone (LH) receptors expressed on CHO cell
55 ave examined their ability to stimulate GnRH/luteinizing hormone (LH) release after peripheral or cen
56 atography was identified as OIF by eliciting luteinizing hormone (LH) release and ovulation in llamas
57 induces negative feedback on pulsatile GnRH/luteinizing hormone (LH) release and positive feedback g
62 es.RESULTSIn healthy women, the amplitude of luteinizing hormone (LH) rise was similar to that after
63 there is no information on the regulation of luteinizing hormone (LH) secretion by NKB or its recepto
64 positive and negative feedback control over luteinizing hormone (LH) secretion during the ovulatory
66 istration of senktide (NK3R agonist) induced luteinizing hormone (LH) secretion in prepubertal and pe
68 s characterized by the pattern of endogenous luteinizing hormone (LH) secretion on the basis of frequ
75 Although mammalian oocytes ovulated after luteinizing hormone (LH) stimulation can be fertilized a
76 riggers germinal vesicle breakdown after the luteinizing hormone (LH) surge and reentry into the meio
77 have demonstrated that IL-1beta inhibits the luteinizing hormone (LH) surge during the afternoon of p
78 e in the generation of the preovulatory GnRH/luteinizing hormone (LH) surge in the female rodent.
80 ntained in prophase meiotic arrest until the luteinizing hormone (LH) surge induces reentry into the
81 ut not males, to display an estrogen-induced luteinizing hormone (LH) surge is consistent with the hi
83 provides for the timing of the preovulatory luteinizing hormone (LH) surge necessary for ovulation i
84 irregular estrous cycles, lack a coordinated luteinizing hormone (LH) surge on the day of proestrus,
85 to escalating levels of estrogen, express a luteinizing hormone (LH) surge that is prompted by a sur
86 GnRH) surge is a prerequisite signal for the luteinizing hormone (LH) surge that triggers ovulation.
91 tion is induced by the preovulatory surge of luteinizing hormone (LH) that acts on the ovary and trig
92 fully grown follicles, prior to the surge of luteinizing hormone (LH) that triggers meiotic resumptio
93 at clearance rates for glycoproteins such as luteinizing hormone (LH) that undergo regulated release
97 n-deficient mice exhibit increased levels of luteinizing hormone (LH), a pituitary hormone that regul
98 d concentrations of estradiol, progesterone, luteinizing hormone (LH), and follicle-stimulating hormo
99 mones follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and that ovarian steroids exer
100 pin's follicle-stimulating hormone (FSH) and luteinizing hormone (LH), both of which are heterodimers
104 BG), dehydroepiandrosterone sulfate (DHEAS), luteinizing hormone (LH), follicle-stimulating hormone (
106 pins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), under the control of pulsatile
107 ine, beta-endorphin, and enkephalin) inhibit luteinizing hormone (LH), vasopressin (VP), and oxytocin
116 se hamster ovary cells expressing either the luteinizing hormone (LH)/chorionic gonadotropin (CG) or
117 ose demonstrating the presence of functional luteinizing hormone (LH)/hCG receptors in human breast c
118 to the pituitary and the resulting surge of luteinizing hormone (LH); however, the neural circuits t
119 r GalNAc to N-linked oligosaccharides on the luteinizing hormone alpha subunit and CA6 but not to tho
120 We measured follicle-stimulating hormone and luteinizing hormone and added information on menstrual p
121 oproteins including the glycoprotein hormone luteinizing hormone and carbonic anhydrase-6 (CA6).
122 A limited number of glycoproteins including luteinizing hormone and carbonic anhydrase-VI (CA6) bear
123 yp2j5 (-/-) mice, but their plasma levels of luteinizing hormone and follicle stimulating hormone wer
125 ce also have decreased circulating levels of luteinizing hormone and follicle-stimulating hormone but
127 pulsatile release of gonadotropin hormones (luteinizing hormone and follicle-stimulating hormone) fr
128 gent induced high levels of the gonadotropin luteinizing hormone and increased the serum concentratio
129 e time course or the plasma concentration of luteinizing hormone and its physiological effects on the
130 -releasing hormone (GnRH) induces a surge of luteinizing hormone and ovulation in a variety of specie
132 restores gonadotrophin secretion, as well as luteinizing hormone and thyroid-stimulating hormone puls
133 nadotropins follicle-stimulating hormone and luteinizing hormone are heterodimeric glycoproteins expr
134 estradiol, follicle-stimulating hormone, and luteinizing hormone around the woman's own mean levels w
135 e required for gonadotrope specification and luteinizing hormone beta (LH beta) gene expression.
136 hether MIP-2A can transcriptionally regulate luteinizing hormone beta (LHbeta), a pituitary-specific
137 riptional activation of both the FSHbeta and luteinizing hormone beta subunit (LHbeta) gene promoters
138 me on DNA and the binding of a TF, using the luteinizing hormone beta subunit gene (Lhb) promoter and
140 utant mouse, whereas proopiomelanocortin and luteinizing hormone beta-subunit expression were normal
142 ycle arrested at prophase of meiosis I until luteinizing hormone from the pituitary acts on the folli
143 onding with an increase in expression of the luteinizing hormone gene, Lhb We demonstrate that poorly
144 one less than 250 ng/dL (or 8.67 nmol/L) and luteinizing hormone greater than 9.85 IU/L, and LCD by t
149 one administration results in suppression of luteinizing hormone in wild-type male mice, but paradoxi
150 arcuate nucleus, and a reduced compensatory luteinizing hormone increase compared with control anima
152 er (13.4+/-3.2 nmol per liter, P<0.001), the luteinizing hormone level increased from 2.7+/-2.0 to 8.
153 one, follicle-stimulating hormone level, and luteinizing hormone level were measured and testicular h
154 had higher follicle-stimulating hormone and luteinizing hormone levels and lower estradiol levels at
155 with BAY 1214784 effectively lowered plasma luteinizing hormone levels by up to 49%, at the same tim
156 , E1, E1S, follicle-stimulating hormone, and luteinizing hormone levels in all patients and the propo
157 ale mice, but paradoxically stimulates serum luteinizing hormone levels in GPRC6A(-/-) null mice.
158 estrous cycles and elevated testosterone and luteinizing hormone levels, suggesting altered hypothala
161 the fasting-associated decrease in overnight luteinizing hormone pulse frequency but had no effect on
162 creases in testosterone and the testosterone/luteinizing hormone ratio were detected in men watching
164 t study investigated regulation of the human luteinizing hormone receptor (hLHR) gene by histone deac
166 n hormones to their cognate human receptors (luteinizing hormone receptor (LHR) and thyroid-stimulati
167 n A (TSA), induces derepression of the human luteinizing hormone receptor (LHR) gene by de-recruitmen
169 ously demonstrated that transcription of the luteinizing hormone receptor (LHR) gene is subject to re
171 the past decade, however, the expression of luteinizing hormone receptor (LHR) has also been reporte
173 mbined systematic mutagenesis studies at the luteinizing hormone receptor and the thyroid-stimulating
174 utant can inhibit signaling to G(s) from the luteinizing hormone receptor by 97% and from the calcito
175 s in the HinRs and the interhelical loops of luteinizing hormone receptor/follicle stimulating hormon
176 erize with its closely related receptor, the luteinizing hormone receptor; this association may have
177 PD-PALM of two functionally defined mutant luteinizing hormone receptors (LHRs), a ligand-binding d
178 as well as human chorionic gonadotropin and luteinizing hormone receptors on male breast tissue, may
180 series induced a much prolonged increase of luteinizing hormone release compared to KP10 and increas
182 n of prostaglandin E2, which then stimulates luteinizing hormone releasing hormone (LHRH) neurons to
183 dy single-chain variable fragment (scFv) and luteinizing hormone releasing hormone (LHRH) peptide, re
188 ne and metabolic variables were measured and luteinizing hormone sampled over 8 hours on days 2 to 5
189 for estradiol-mediated suppression of tonic luteinizing hormone secretion (an indirect measure of Gn
192 rs in GnIH-ir nuclei, and GnIH inhibition of luteinizing hormone secretion indicate the discovery of
193 the stress-induced suppression in pulsatile luteinizing hormone secretion observed in control mice.
194 stent with a role in regulating preovulatory luteinizing hormone secretion, rostral projections from
195 ted a robust GnRH discharge, as reflected by luteinizing hormone secretion, which was abolished by pr
200 otein increased >10-fold after the ovulatory luteinizing hormone surge in wild-type but not PRKO mice
201 t in the ovary for extended periods before a luteinizing hormone surge induces entry into the first m
203 losa cells of periovulatory follicles by the luteinizing hormone surge through a progesterone recepto
205 ein alters the amplitude of the preovulatory luteinizing hormone surge, likely by perturbing GnRH rel
206 n several hours after the ovulation-inducing luteinizing hormone surge, whereas they undergo differen
207 kisspeptin is involved in generation of the luteinizing hormone surge, which is required for ovulati
208 d by the puberty-triggering and preovulatory luteinizing hormone surge-mediating peptide, kisspeptin.
213 nts with abnormal levels of testosterone and luteinizing hormone was less pronounced-57% and 21%, res
214 estradiol, total and free testosterone, and luteinizing hormone were higher by 5.26% (95% CI: 1.27%,
215 We used transgenic mice that overexpress luteinizing hormone with subsequent ovarian hyperstimula
216 ed puberty associated with low or apulsatile luteinizing hormone) in both humans and in the mouse mod
218 ic antigen, thyroid stimulating hormone, and luteinizing hormone) were printed in an array format ont
220 strous mice that robust pulsatile release of luteinizing hormone, a proxy for GnRH, emerges abruptly
221 Ratios of follicle stimulating hormone to luteinizing hormone, a sexual maturity indicator, in all
222 sisting of an alpha subunit, also present in luteinizing hormone, and a unique beta subunit, which is
223 ormones: human chorionic gonadotropin, human luteinizing hormone, and follicle stimulating hormone by
225 erum levels of CRP, estradiol, progesterone, luteinizing hormone, and follicle-stimulating hormone we
226 droepiandrosterone (DHEAS), androstenedione, luteinizing hormone, and follicle-stimulating hormone.
227 d levels of follicle-stimulating hormone and luteinizing hormone, and increased variability of estrad
230 l follicles, independently of an increase in luteinizing hormone, and this phenotype can be reversed
231 energy, vitamin E intake, physical activity, luteinizing hormone, follicle-stimulating hormone, and p
232 nophore-induced acrosome reaction as well as luteinizing hormone, follicle-stimulating hormone, and t
234 t explained by any deficits in testosterone, luteinizing hormone, or follicle-stimulating hormone con
235 ens, disrupted reproductive cycles, and high luteinizing hormone, the latter reflecting increased gon
236 tes pituitary synthesis of a large amount of luteinizing hormone, which is required for ovulation.
238 e generated by breeding MMTV-Neu mice with a luteinizing hormone-overexpressing mouse model of ovaria
239 /23), mainly in follicle-stimulating hormone/luteinizing hormone-producing (38%) and null cell (57%)
240 ombesin (AN-215), somatostatin (AN-238), and luteinizing hormone-releasing hormone (AN-207) consisted
243 orticotropic hormone (ACTH) and hypothalamic luteinizing hormone-releasing hormone (LHRH) agonist, [D
245 the recent developments on BPH therapy with luteinizing hormone-releasing hormone (LHRH) antagonist
246 tance and (5) a modified synthetic analog of luteinizing hormone-releasing hormone (LHRH) as a target
247 gs (prodigiosin or paclitaxel) conjugated to Luteinizing Hormone-Releasing Hormone (LHRH) for the spe
251 estigate the mechanism by which Mn2+ induces luteinizing hormone-releasing hormone (LHRH) secretion f
252 s by which the neuroendocrine brain controls luteinizing hormone-releasing hormone (LHRH) secretion.
254 large doses of Cetrorelix, an antagonist of luteinizing hormone-releasing hormone (LHRH), reduces le
255 naling pathway that prompts the secretion of luteinizing hormone-releasing hormone (LHRH), the neurop
258 ng afferent pathways to neurons synthesizing luteinizing hormone-releasing hormone (LHRH, also known
259 (68)Ga-PSMA-11 PET imaging in hormone-naive (luteinizing hormone-releasing hormone [LHRH] +/- bicalut
260 itive tumors also received letrozole (plus a luteinizing hormone-releasing hormone [LHRH] agonist if
261 diation plus immediate androgen suppression (luteinizing hormone-releasing hormone [LHRH] agonist), w
262 steroid ablation using leuprolide acetate, a luteinizing hormone-releasing hormone agonist (LHRHa), i
263 d) (PLGA) microspheres encapsulating a model luteinizing hormone-releasing hormone agonist (LHRHa)-ba
265 AST, which was defined as 6 months of both a luteinizing hormone-releasing hormone agonist and an ant
266 ts receiving combined androgen blockade with luteinizing hormone-releasing hormone agonist and bicalu
267 les, followed by total androgen suppression (luteinizing hormone-releasing hormone agonist plus bical
268 n deprivation (AD) to cixutumumab added to a luteinizing hormone-releasing hormone agonist with bical
269 S; two injections of every-3-months depot of luteinizing hormone-releasing hormone agonist) to primar
270 Patients were randomly assigned 2:1 to a luteinizing hormone-releasing hormone agonist, bicalutam
273 ; and three, when chemical suppression using luteinizing hormone-releasing hormone agonists is the ch
274 of 5 ng per milliliter or higher received a luteinizing hormone-releasing hormone analogue and an an
276 s monotherapy or with adjuvant castration or luteinizing hormone-releasing hormone superagonists to b
277 k suggests that cytotoxic peptide analogs of luteinizing hormone-releasing hormone, somatostatin, and
278 hormone-secreting (GH-secreting) GH3 cells, luteinizing hormone-secreting (LH-secreting) LbetaT2 cel
286 ine 3 (Org 41841), a partial agonist for the luteinizing hormone/choriogonadotropin receptor (LHCGR)
289 identified previously as an agonist for the luteinizing hormone/chorionic gonadotropin receptor (LHC
290 mical analysis colocalized expression of the luteinizing hormone/chorionic gonadotropin receptor, PRO
292 third transmembrane alpha-helix (TM3) of the luteinizing hormone/human chorionic gonadotropin recepto
293 ecreased circulating testosterone, increased luteinizing hormone/testosterone ratio, and decreased ex
294 ollicular differentiation markers, including luteinizing-hormone receptor (LHR), inhibin-alpha, micro
295 increased levels of follicle stimulating and luteinizing hormones, and 8.52-fold increased risk of Le
297 5a prevents follicle-stimulating hormone and luteinizing protein from up-regulating the CTNNB1 and CR
299 inducing cells, the identification of mutant luteinized theca cells may add crucial evidence in under
300 ether, our results suggest that GT198 mutant luteinized theca cells overexpressing CYP17 are common i