ライフサイエンスコーパス: lymphohematopoietic

1 we examined the role of POSTN-ITGAV axis in lymphohematopoietic activity in spleen that hosts a rare

2 h strong self-renewing capacities (e.g., the lymphohematopoietic and gastrointestinal systems), while

3 Patients exhibited increased incidence of lymphohematopoietic and non-lymphohematopoietic second m

4 of the genotypic reversion, we examined each lymphohematopoietic and stromal cell lineage in an FA pa

5 etween alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agr

6 mong spouses, relative SMRs exceeded 1.0 for lymphohematopoietic cancers and malignancies of the dige

7 ficant increasing trend for incidence of all lymphohematopoietic cancers associated with lifetime exp

8 Among G2, mortality rates associated with lymphohematopoietic cancers in men and lung and cervix u

9 he relative mortality ratio was elevated for lymphohematopoietic cancers, melanoma, and digestive sys

10 Using bone marrow chimeras, we show that lymphohematopoietic cell lineages largely dictate the pr

11 oposide-induced antiproliferative effects in lymphohematopoietic cell lines and acute myelogenous leu

12 show that up to 80% of BAK (but not BAX) in lymphohematopoietic cell lines is oligomerized and bound

13 hematopoietic stem cells and in a variety of lymphohematopoietic cell lines.

14 It is unknown if other lymphohematopoietic cell populations can be used as a DS

15 nce model, injection of adult semiallogeneic lymphohematopoietic cells (spleen cells [SC] and bone ma

16 he development of multiple lineages of human lymphohematopoietic cells and formation of secondary lym

17 s that give rise to these yolk sac primitive lymphohematopoietic cells and the molecular events contr

18 t mouse embryonic stem (ES) cells to various lymphohematopoietic cells is an in vitro model of the he

19 ggest that TGF-beta1 overexpression by donor lymphohematopoietic cells may enhance tolerance inductio

20 fold-higher level of ADA expression in human lymphohematopoietic cells than the PA317/LASN vector cur

21 Thus, dendritic cells and macrophages clear lymphohematopoietic cells that have downregulated CD47 d

22 This resistance is mediated by lymphohematopoietic cells transplanted with the graft, s

23 immunizations of the donor strains with host lymphohematopoietic cells were used.

24 a critical indicator for determining whether lymphohematopoietic cells will survive or be cleared.

25 in the clearance of virtually all CD47(-/-) lymphohematopoietic cells within 1 day after infusion.

26 liminate both normal and malignant host-type lymphohematopoietic cells without causing injury to nonl

27 ad the unique capacity to eliminate the host lymphohematopoietic cells without nonlymphohematopoietic

28 pulation with a comprehensive array of human lymphohematopoietic cells, including T cells, B cells, a

29 but also both primitive and definitive human lymphohematopoietic cells.

30 ailed to eliminate malignant and normal host lymphohematopoietic cells.

31 iferation, differentiation, and apoptosis in lymphohematopoietic cells.

32 Multilineage lymphohematopoietic chimerism (5%-80% donor CD3+ or CD3-

33 report of the deliberate induction of mixed lymphohematopoietic chimerism after a nonmyeloablative p

34 Mixed lymphohematopoietic chimerism can provide an effective m

35 a with end-stage renal disease through mixed lymphohematopoietic chimerism has been achieved, as evid

36 sociation with either transient or sustained lymphohematopoietic chimerism has been demonstrated in s

37 viously demonstrated that induction of mixed lymphohematopoietic chimerism resulted in donor specific

38 eparative therapy for the induction of mixed lymphohematopoietic chimerism, we treated a 55-year-old

39 allotolerance through the induction of mixed lymphohematopoietic chimerism.

40 w transplantation and the induction of mixed lymphohematopoietic chimerism.

41 host disease, and the establishment of mixed lymphohematopoietic chimerism.

42 oth recipients also exhibited GvH-associated lymphohematopoietic compartment (LHC) alterations as evi

43 demonstrated that a signaling event in a non-lymphohematopoietic compartment of the lung prevented th

44 specifically at the stem/progenitor stage of lymphohematopoietic development that appears to regulate

45 the inhibition of GVHD lethality and delayed lymphohematopoietic effects of the combined MoAb regimen

46 immunosuppress the recipient to permit donor lymphohematopoietic engraftment and thereby establish a

47 Nine patients had long-term, stable donor lymphohematopoietic engraftment at levels that sufficed

48 nonreactive siblings, have maintained stable lymphohematopoietic engraftment with donor cells for gre

49 or are being used for the reconstitution of lymphohematopoietic function after myeloablative, near-m

50 r lymphocyte infusions (DLIs) manifesting as lymphohematopoietic graft-versus-host (LH-GVH) and graft

51 given to stable mixed chimeras resulting in lymphohematopoietic graft-versus-host (LH-GVH) response.

52 llo-HCT recipients is due to augmentation of lymphohematopoietic graft-versus-host reaction (LGVHR) a

53 experiments show that reconstitution of all lymphohematopoietic lineages across the entire MHC trans

54 s, including the progenitor cells of all the lymphohematopoietic lineages and lymphohematopoietic ste

55 Patients with a lymphohematopoietic malignancy considered to be at high

56 n and expansion of donor lymphocytes in both lymphohematopoietic organs and GVHD target tissues of IF

57 Chimerism in the peripheral blood and lymphohematopoietic organs was assessed by flow cytometr

58 rum analyses on infected ferrets to identify lymphohematopoietic parameters associated with mild to s

59 During mouse development, the first lymphohematopoietic precursor cells and myeloid or eryth

60 There they generate primitive lymphohematopoietic precursor cells and the first erythr

61 ent stem cells showed a reduced expansion of lymphohematopoietic progenitor cells and defects of thym

62 CD7+CD34+ lymphohematopoietic progenitor cells in bone marrow are

63 tuted with SYK-deficient fetal liver-derived lymphohematopoietic progenitor cells show a block in B-c

64 abrogates the lymphoid potentials of murine lymphohematopoietic progenitors and the reconstituting a

65 We isolated the earliest lymphohematopoietic progenitors by using embryonic stem

66 First, we tested the effects of IL-3 on lymphohematopoietic progenitors by using lineage-negativ

67 e gene defect at the level of the autologous lymphohematopoietic progenitors could therefore represen

68 urface marker that can identify the earliest lymphohematopoietic progenitors in mouse development.

69 proposed to be related to either defects in lymphohematopoietic progenitors or the thymic microenvir

70 However, the earliest lymphohematopoietic progenitors that appear during mouse

71 Multipotent lymphohematopoietic progenitors were generated later as

72 evated the CD34(+) cell population though no lymphohematopoietic progenitors were induced.

73 r mixed NK cell colony formation from single lymphohematopoietic progenitors.

74 Remarkably, antihost lymphohematopoietic reactions, including GVL effects aga

75 ernative donor sources can provide effective lymphohematopoietic reconstitution, but time to engraftm

76 m the same donor achieves multilineage human lymphohematopoietic reconstitution, including dendritic

77 MoAb infusion resulted in impaired lymphohematopoietic recovery in congenic BMT recipients

78 transplanted single SP cells are capable of lymphohematopoietic repopulation at near absolute effici

79 sed incidence of lymphohematopoietic and non-lymphohematopoietic second malignancies and no secondary

80 ly because of back mutation, originated in a lymphohematopoietic stem cell and not solely in a lympho

81 iability suggest that mutations arise in the lymphohematopoietic stem cell compartment and that these

82 The availability of lymphohematopoietic stem cell lines should facilitate th

83 ate the spontaneous genotypic reversion in a lymphohematopoietic stem cell.

84 The site of origin of lymphohematopoietic stem cells (HSC) that initiate defin

85 The classical definition of lymphohematopoietic stem cells (LHSC), the most primitiv

86 of all the lymphohematopoietic lineages and lymphohematopoietic stem cells (stem cells).

87 ntial therapeutic approaches by manipulating lymphohematopoietic stem-progenitor cells to express Fas

88 roper and they were able to reconstitute the lymphohematopoietic system of irradiated mice.

89 -versus-host (GVH) reactions confined to the lymphohematopoietic system without inducing graft-versus

90 ficial alloresponse to take place within the lymphohematopoietic system, leading to graft-versus-lymp

91 mias and lymphomas reside largely within the lymphohematopoietic system, we have proposed that the de

92 tients with life-threatening diseases of the lymphohematopoietic system.

93 ectively in adult tissues and in cell of the lymphohematopoietic system.

94 -/-) mice had normal cellular composition in lymphohematopoietic tissues, but T-bet(-/-) lymphocytes

95 r cell chimerism in the peripheral blood and lymphohematopoietic tissues.

96 fining of the donor CD8+ T-cell expansion to lymphohematopoietic tissues.

97 ice were transplanted with porcine and human lymphohematopoietic tissues.

98 of the graft-versus-host alloresponse to the lymphohematopoietic tissues.

99 trated expression of the SLA DR transgene in lymphohematopoietic tissues.

100 phology in the thymus, and with chimerism in lymphohematopoietic tissues.

101 rving their beneficial antitumor activity in lymphohematopoietic tissues.

102 genitor transplantation to effectively treat lymphohematopoietic tumors and reduce early toxicity.