ライフサイエンスコーパス: lysis

1 uced a mild cell-chaining phenotype and cell lysis.

2 ile DNA barcodes can only be read after cell lysis.

3 e rate of PL transport during mlaA*-mediated lysis.

4 ed from the RI-T complex to ensure efficient lysis.

5 repressor (cI(VP882)), leading to host-cell lysis.

6 ng ion channels within the parasite, causing lysis.

7 ound in the cell envelope, thus causing cell lysis.

8 hereby limiting CD3 bsAb-mediated tumor cell lysis.

9 d in vivo toxicity from nonspecific membrane lysis.

10 cell wall substrate, thus promoting osmotic lysis.

11 ipid reorganization during PFT-mediated cell lysis.

12 uding induction of spheroplasts and membrane lysis.

13 rrounding waters (extracellular) during cell lysis.

14 is use distinct mechanisms to cause hemocyte lysis.

15 ults in a transmembrane pore leading to cell lysis.

16 unctional pores that eventually lead to cell lysis.

17 d is more susceptible to detergent-triggered lysis.

18 cells to mediate intestinal epithelial cell lysis.

19 ue to cells retrieved while undergoing viral lysis.

20 maturation and eventual release through cell lysis.

21 insulin secretion for protection from viral lysis.

22 accumulation of glycerol and subsequent cell lysis.

23 s of preventing artifacts caused by cellular-lysis.

24 n red blood cells, it is also known to cause lysis.

25 t and disrupt cellular membranes, leading to lysis.

26 ring and enhanced CD3 bsAb-mediated AML cell lysis.

27 y-patterned face (xy) for cell isolation and lysis.

28 reasing their immunogenicity without causing lysis.

29 se by destroying phagocytes through targeted lysis.

30 quires all three components for maximal cell lysis.

31 on interactions-and how this relates to cell lysis.

32 s cause a surge of osmolarity and rapid cell lysis.

33 es a synergistic response that leads to cell lysis.

34 prevent CAMP binding, which can lead to cell lysis.

35 g also induced T cell mediated leukemia cell lysis.

36 r induction of caspase-1-mediated macrophage lysis.

37 ntil the membrane undergoes scission through lysis.

38 cell's plasma membrane area to prevent cell lysis.

39 DNA damage occurs, triggering viral-mediated lysis.

40 les its conditional inactivation during cell lysis.

41 erial invasion attempts leading to host cell lysis.

42 0%, slowing shrinkage of the IM and delaying lysis.

43 mobilizing to new host cells following cell lysis.

44 ss, and do not necessarily require bacterial lysis.

45 the ECA-deficient thyA mutants precede cell lysis.

46 hment appears to lead to host cell death and lysis.

47 he death of individual host cells from lytic lysis.

48 nutrients and organic material through host lysis.

49 protection against toxin-mediated neutrophil lysis.

50 tion of the substrate AMA1 produces host RBC lysis.

51 shape of fibrin spatial distribution during lysis.

52 ns in a very short time interval after phage lysis.

53 ns where nearly all cells undergo programmed lysis.

54 s an emergency release valve preventing cell lysis.

55 olipids, leading to membrane damage and cell lysis(1,2).

56 ic reprogramming of infected cells and viral lysis alter nutrient cycling and carbon export in the oc

57 isplayed increased sensitivity to complement lysis and a significant reduction in survival within per

58 ssociated with unstable globins and red cell lysis and also insights into the factors governing hemog

59 nic polymer-modified magnetic beads prior to lysis and analyzed by electrochemical impedance spectros

60 es (TIGKs) by measuring cell viability, cell lysis and apoptosis.

61 reveals that the MW heating favors cellular lysis and cell content agglutinates.

62 n of the cytoplasmic membrane accompanied by lysis and cell death.

63 can operate in the absence of complete cell lysis and cell death.

64 Continuous lytic cell lysis and de novo infection allowed LEC culture to remai

65 mer that safeguards bacteria against osmotic lysis and determines cellular morphology.

66 composition, redistribute nutrients via host lysis and drive evolution through horizontal gene transf

67 om on-chip cell lysis, conventional off-line lysis and ELISA confirmed accuracy.

68 oteomic method called accelerated Barocycler lysis and extraction (ABLE) to assess the depth of infor

69 cision repair reaction, are isolated by cell lysis and fractionation, followed by immunoprecipitation

70 s contain apolipoprotein L-1 contributing to lysis and haptoglobin-related protein (HPR), which can f

71 hich replicate in cancer cells, induce tumor lysis and immune priming, but their immune consequences

72 Furthermore, oxidizing TNBC cells prior to lysis and incorporation into SNAs (OxLys-SNAs) significa

73 After lysis and incubation-during which the PTP enzymes act on

74 We identify several variants of both lysis and lysogeny - one wild type and one modified beha

75 e preserved - these behaviours correspond to lysis and lysogeny.

76 ng site affinities to achieve both wild type lysis and lysogeny.

77 te removal of cell-free RNAs, efficient cell lysis and mRNA capture, achieving highest mRNA detection

78 of root elongation, when root cortical cell lysis and nitrate uptake, as well as cytokinin concentra

79 Although cell lysis and outer-membrane vesicle extrusion are possible

80 ost survival with lysogen formation, or host lysis and phage production.

81 Cell lysis and proteoform pre-fractionation by gel-eluted liq

82 t from apoptosis due to their characteristic lysis and release of cellular components that promote di

83 viral environments or following cell/virion lysis and removal of proteins.

84 of Plasmodium-infected erythrocytes through lysis and removal of uninfected erythrocytes.

85 Following cell lysis and sampling crude cell lysate for analysis, the s

86 exoskeleton that protects them from osmotic lysis and specifies their distinct shapes.

87 EMCV replication and EMCV-mediated beta-cell lysis and that this protection is associated with an inh

88 ion of Triton X-100 and CoQ10 causes the MLs lysis and the cresyl violet oxidation, obtaining a decre

89 gh T6SS-mediated killing versus passive cell lysis and the extent of the transfers that occur due to

90 Cell lysis and the peak in Stx1 production were substantially

91 C exposure led to pathogen death due to cell lysis and was enough for pathogen clearance.

92 extractions utilizes sequential additions of lysis and wash buffers followed by elution.

93 s is prone to artifacts associated with cell lysis and whole-genome amplification.

94 ect to greater loss rates (likely from viral lysis and zooplankton grazing).

95 To integrate the culture, lysis, and assay workflow, we introduce a one-step copol

96 oes not require centrifugation or mechanical lysis, and can be readily implemented in any clinical mi

97 ed a method for performing all cell culture, lysis, and deglycosylation steps in 96-well microplates

98 irion structure and assembly, DNA packaging, lysis, and DNA metabolism.

99 ly entered lytic replication, underwent cell lysis, and released new virus.

100 association with O. tauri debris after viral lysis, and unlike other allomers were not observed befor

101 danger signals released in response to cell lysis, apoptosis, degranulation, or membrane pore format

102 The proposed method utilized a lysis approach to remove hemoglobin from the suspension

103 The mechanisms that contribute to rapid cell lysis are largely unexplored.

104 Piggyback-the-Winner model of reduced phage lysis at higher host densities.

105 e MESMER assay versus a comparable detergent lysis-based assay, cellular Fura-2 Mn extraction assay,

106 Ambient RNA is caused by cell lysis before droplet partitioning and is an important co

107 re first sorted into a well plate containing lysis buffer and a phosphopeptide substrate.

108 The array lyses cells on-chip in lysis buffer augmented with a 2s pulse of a sonic cell d

109 a glass slide, after which a laminar flow of lysis buffer extends the lysed chromatin fibers parallel

110 lect, store and homogenize the sample in RLT lysis buffer from the RNeasy Fibrous Tissue Kit combined

111 ing using hydrodynamic flow confinement of a lysis buffer, followed by electrokinetic purification of

112 solation Kit with an overnight incubation in lysis buffer, resulted in DNA extraction with the highes

113 known function, affords self-protection from lysis by AmpDh3.

114 t viral replication and subsequent beta-cell lysis by attenuating mitochondrial oxidative metabolism

115 V+ Burkitt lymphoma (BL) sensitized cells to lysis by EBV-specific cytotoxic T cells (EBV-CTLs).

116 Vs impacted cellular calcification absent of lysis by inducing dramatic shifts in optical side scatte

117 etabolism attenuates EMCV-mediated beta-cell lysis by inhibiting viral replication.

118 protects beta-cells against virally mediated lysis by limiting EMCV replication.

119 olecules, but leaves the cells vulnerable to lysis by natural killer (NK) cells.

120 ics of bacterial growth, cell morphology and lysis, cancer-related gene expression, and metabolomics.

121 ith Candida albicans, but a lower macrophage lysis capacity.

122 rocytes, CM14 impedes host cell rounding and lysis caused by V. vulnificus.

123 specially compared it with the commonly used lysis-centrifugation-based purification method (STEM met

124 A lysis chamber and reagent compartments deliver sample an

125 ead ChIA-PET that includes cell fixation and lysis, chromatin fragmentation by sonication, ChIP, prox

126 g the dormant phenotype with a 'stress-gated lysis circuit'.

127 Our crude DNA lysis combined with LAMP-AuNP/STR present effective poin

128 ion is specific and strong enough to survive lysis conditions, enabling a biotin analogue of ipomoeas

129 ions (i.e., single cell sampling probe, cell lysis container, microreactor, and nano-ESI emitter) in

130 gest that DNA release by phage-mediated cell lysis contributes to C. difficile biofilm formation.

131 orrelation between results from on-chip cell lysis, conventional off-line lysis and ELISA confirmed a

132 We found Thermus thermophilus sensitive to lysis D (SlyD) and Thermococcus gammatolerans SlyD FK-50

133 t alleles that restored plaque formation for lysis-defective mutants of Rz and Rz1 were selected.

134 ck, chitin-reinforced cell walls render cell lysis difficult, complicating their analysis and identif

135 tform for performing single-cell freeze-thaw lysis directly toward 3' mRNA sequencing.

136 eveals the oligomers that are protected from lysis due to their tight association with the protein, a

137 ng invasion and to host cell plasma membrane lysis during egress.

138 We expand luciferase multiplexing in post-lysis endpoint luciferase assays from two to six.

139 roke Trials Archive-ICH trials dataset, Clot Lysis: Evaluating Accelerated Resolution of Intraventric

140 h second-site suppressor mutations supported lysis events that were preceded by spherical cell format

141 n modules capable of performing the chemical lysis, filtration, sample mixing with antibodies, and el

142 m of antibiotic- and/or growth phase-induced lysis for other important Gram-positive pathogens.

143 ation-optimizing beneficial mutations during lysis from sequence diversification during lysogeny, all

144 sources used for confident identification of lysis genes such as spanins, and methods used for identi

145 p=0.21]); and no hyperfibrinolysis (maximum lysis >15%).

146 aximum clot firmness (50-72 mm), and maximum lysis (>15% at 1 h).

147 haride (LPS), a toxic byproduct of bacterial lysis, has been extensively used to stimulate inflammato

148 MII oocyte microinjection reduced lysis, improved blastocyst rate, increased the number of

149 ed liposomes to induce efficient fibrin clot lysis in a fibrin-agar plate model and the encapsulated

150 analyze the dynamics of membrane bulging and lysis in Escherichia coli, in which the formation of an

151 ut also for the temporal regulation of phage lysis in general.

152 However, cell lysis in microwells remains challenging despite the rece

153 rs a wild-type allele of uppS, also promoted lysis in mutants lacking PBP1B or bPBP activity.

154 by plasma membrane pores, similarly to cell lysis in pyroptosis and necroptosis(3,4).

155 Lysis in response to these drugs requires the activity o

156 We reprogram phages to activate lysis in response to user-defined cues.

157 pic and is released from hepatocytes without lysis in small vesicles that resemble exosomes(2,3).

158 ng apoptosis yet which differs after nuclear lysis in that mitochondria are not degraded but are modi

159 c antibody efficiently induces targeted cell lysis in the presence of effector cells at as low as sub

160 This process is partially lysis independent and inhibited by ATP.

161 ultistep process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitizing c

162 T can be blocked by an antiholin (RI) during lysis inhibition (LIN).

163 Through lysis inhibition disruption a conserved PLE protein, Lid

164 Here, we discover lysis inhibition in the etiological agent of the diarrhe

165 dies link a novel incarnation of the classic lysis inhibition phenomenon with conserved defensive fun

166 discovered environmental sensing by phages, lysis inhibition, has only been characterized and studie

167 lin, teaA, and antiholin, arrA, that mediate lysis inhibition.

168 the defensive phage satellite PLE, collapses lysis inhibition.

169 nlargement of wall defects, after which cell lysis is consistent with both the inner and outer membra

170 cted cell undergoes superinfection, then the lysis is delayed until host/phage ratio becomes more fav

171 globin concentration released by erythrocyte lysis is likely to perturb Nf-L detection in DBS elute.

172 We show DNA released via cell lysis is readily available for HGT and may be partially

173 g of individual phage infections affects the lysis-lysogeny decision of bacteriophage lambda despite

174 grate host cell density information into the lysis-lysogeny decision.

175 on system, termed "arbitrium," to coordinate lysis-lysogeny decisions.

176 ntegrate host-derived information into their lysis-lysogeny decisions.

177 In the absence of lysis, MAC may induce intracellular signaling and cell a

178 in certain environments after cell death and lysis, magnetosome magnetite crystals contribute to the

179 Here, we show that cell lysis may be enabled by a process of toxins targeting re

180 a novel, low-field-enabled electromechanical lysis mechanism of bacterial cells using electroconvecti

181 of action for these antibiotics include cell lysis, membrane depolarization, inhibition of cell wall

182 Freeze-thaw, known as an unfavorable lysis method resulting in possible RNA fragmentation, tu

183 When harsh lysis methods are used to extract DNA, 2 oral mycobiome

184 nto rapidly expanding pores causing membrane lysis (minutes).

185 The VHA maximum lysis (ML) lower threshold was determined to be <5%.

186 Thus, our data show that, prior to cell lysis, non-enveloped viruses are secreted within infecti

187 apse 3D confocal microscopy showed that self-lysis occurs locally at even higher frequencies (~94%) a

188 sis to the DNase colicin, we found that mass lysis occurs when cells are going to die anyway from tox

189 In T4 phage infection, lysis occurs when the holin protein (T) forms lesions in

190 tants in vivo Unlike the wild type, in which lysis occurs while the cells retain a rod shape, reverta

191 Surgeons should approach laparoscopic lysis of adhesions with a higher level of awareness and

192 The former results in lysis of bacterial cells and phage release (resulting in

193 We propose that the mechanical lysis of bacterial cells can be influenced by the degree

194 atients, with half of these cases triggering lysis of CD4+ T cells.

195 mally adapted state; it however induced full lysis of cultured cancer cells upon light irradiation.

196 ed the furrow ingression and led to frequent lysis of daughter cells.

197 R) and demonstrated specific recognition and lysis of HLA-A*02:01-positive DeltaNPM1 AML after retrov

198 suggest that in addition to neutralization, lysis of infected cells by Abs can effectively participa

199 Complement-dependent lysis of IVIg against these pig pRBCs was measured by he

200 ing the molecular pathways that culminate in lysis of neutrophils during CA-MRSA infection may serve

201 rmed on microtiter wells resulted in thermal lysis of nitro-explosives to generate nitrite ions.

202 Thus, antibody-dependent lysis of P. falciparum-infected RBCs by NK cells may be

203 Interestingly, ex vivo lysis of patient thrombi was more successful when adding

204 anical stress activates Pkc1, which prevents lysis of pheromone-treated cells by inhibiting polarized

205 coded by Campylobacter megaplasmids mediates lysis of RBCs and likely contributes to survival on reta

206 lular DNA was targeted by performing ex vivo lysis of retrieved thrombi with DNase 1 and t-PA.

207 P. aeruginosa LasA endopeptidase potentiates lysis of S. aureus by vancomycin, rhamnolipids facilitat

208 ncreases the efficacy of complement-mediated lysis of serum-resistant P. aeruginosa strains, indicati

209 t extracellular histone H4-mediated membrane lysis of smooth muscle cells (SMCs) triggers arterial ti

210 (TAs) play a key role in penicillin-induced lysis of the Gram-positive pathogen Streptococcus pneumo

211 of bacterial viruses, or bacteriophages, is lysis of the host.

212 propagation depends on the regulation of the lysis of the infected host cell.

213 caps the daughter poles and prevents osmotic lysis of the newborn cells.

214 Viral infection led to mass cell lysis of the O. tauri cells within 48 h.

215 1 in trypanosome endosomes leads to eventual lysis of the parasite due to increased plasma membrane c

216 nal release of silver ions (Ag(+) ) leads to lysis of the pathogen accumulated within the microtrap c

217 In addition, on-chip elusion and lysis of the protein and RNA content of captured exosome

218 Enzymatic lysis of the protein-bound heparin chains followed by th

219 Recognition by NK cells can lead to direct lysis of the target cell and production of the signature

220 Lysis of tumour cells releases tumour-specific antigens

221 cholesterol levels modulate the preferential lysis of uninfected host cells by SLO, and therefore mod

222 gets without the interfering effects of cell lysis on vacuole polyP and of endopolyphosphatases.

223 The vortex-assisted lysis only requires a field strength of approximately 10

224 e system's main biological functions include lysis, opsonization, and recruitment of phagocytes.

225 monstrated >90% viability and no significant lysis or apoptosis relative to untreated cells.

226 d mechanism is independent of explosive cell lysis or cell death, and the release of DNA is confined

227 Here, we review four "single-gene lysis" or Sgl proteins.

228 ther allomers were not observed before viral lysis, or during cell death due to growth limitation.

229 Membrane lysis, or rupture, is a cell death pathway in bacteria f

230 s to either abortive invasion with rapid RBC lysis, or successful entry but developmental arrest.

231 US combined with OFP t-ELIP enhanced lysis over OFP t-ELIP alone (p < 0.01).

232 amined the relationship between viscoelastic lysis parameters and clinical outcomes, with resulting t

233 eveals the straight radial boundaries in the lysis pattern as a telltale sign for coexistence and co-

234 ges are the key to formation of the observed lysis pattern.

235 The cell lysis potential of different IL/buffer combinations was

236 ds to host-produced DPO, launching the phage lysis program via an antirepressor that inactivates the

237 emorrhage with erythrocyte extravasation and lysis promotes osteoblastic differentiation of smooth mu

238 itor 1 (PAI-1) controlled both the extent of lysis propagation and the shape of fibrin spatial distri

239 e lytic ssDNA and ssRNA phages have a single lysis protein that achieves cell lysis without enzymatic

240 n protein, A2, has an additional role as the lysis protein, by its ability to bind and inhibit MurA,

241 ated the mechanism of action of an unrelated lysis protein, Lys(M), of the Escherichia coli levivirus

242 dsDNA phages require multiple lysis proteins, including at least one enzyme that degra

243 ne R(2) rates, we have developed an improved lysis protocol for removing confounding molecular and ce

244 Mechanisms such as exudation and cell lysis release these phytoplankton-derived sulfur metabol

245 s showed that prophage-induced Halanaerobium lysis releases intracellular metabolites that can sustai

246 al understanding of the processes leading to lysis remains lacking.

247 cellular manganese (Mn) levels require cell lysis, restricting longitudinal experiments and multiple

248 Cell lysis solvent and PB reagent (acetone or benzophenone) a

249 pe and specifically eliminates, through cell lysis, sporulating cells that assemble the envelope inco

250 e by species and require an additional viral lysis step.

251 ocess induced by apoptosis, necrosis or cell lysis substances, respectively.

252 rupture; characterization of mlaA*-mediated lysis suggested that PL transport can occur via a high-f

253 hereas VqmA(Vc) cannot induce phage-mediated lysis, suggesting an asymmetry whereby the phage influen

254 ere pneumonia (in five [29% patients); tumor lysis syndrome (in three [18%] patients); and sepsis, at

255 prostate cancer, and the occurrence of tumor lysis syndrome (TLS) with (177)Lu-labeled peptides has n

256 Safety, including incidence of tumor lysis syndrome (TLS), did not differ between schedules (

257 Tumour lysis syndrome is a complication of chemotherapy for hae

258 e was not observed, whereas laboratory tumor lysis syndrome was documented in three patients.

259 Clinical tumor lysis syndrome was not observed, whereas laboratory tumo

260 No tumor lysis syndrome was observed.

261 A single case of biochemical tumor lysis syndrome was observed.

262 ropenia occurred in 16% of cycles, and tumor lysis syndrome was rare.

263 eters, and clinical manifestations of tumour lysis syndrome, and the prophylaxis and treatments avail

264 acute kidney failure, grade 3, due to tumor lysis syndrome, overall nephro- and hepatotoxicity was l

265 nd have a low incidence of associated tumour lysis syndrome.

266 ee patients had laboratory evidence of tumor lysis syndrome.

267 apoptosis and increasing the risk for tumour lysis syndrome.

268 ratory and clinical manifestations of tumour lysis syndrome.

269 oportionally greater lowering of the vesicle lysis tension and hydration repulsive pressure that comb

270 the form of an antibody-mediated complement lysis test, the trypanolysis test, but biosafety issues

271 is diluted into blood plasma after red cell lysis, the disassembly pathway appears to be dominated b

272 ocation of cell wall degradation would cause lysis, the initiation of cell fusion must be highly regu

273 mulate large amounts of polyP, and upon cell lysis, the release of the vacuolar polyP could nonphysio

274 In human plasma, F5 and G2 prolonged clot lysis time from 9.8 +/- 1.1 minutes in the absence of Af

275 enhanced clot stability and lengthened clot lysis time in blood from F8-/-/PN-1-/- and from patients

276 ared with 40 healthy volunteers, median clot lysis times (CLTs) were shorter in patients with AD but

277 ease context, highlighting the importance of lysis timing during infection and parasitization.

278 xperimentally assessed metabolites from cell lysis to better understand viral roles in this ecosystem

279 election, and yet many bacteria undergo cell lysis to release anti-competitor toxins [1-5].

280 Sample analysis includes 5-min lysis to release intracellular parasites, and stirring f

281 By exposing E. coli that do not perform lysis to the DNase colicin, we found that mass lysis occ

282 However, bacterial lysis typically requires at least a 10-fold higher elect

283 ition relevant for the regulation of spatial lysis up to its arrest.

284 g nonphosphorylatable Ste5 undergo increased lysis upon mechanical stress and exhibit defects in cell

285 challenge of sample homogenization and cell lysis using magnetic rotation of an external magnet, at

286 of the complement cascade induces tumor cell lysis via complement-dependent cytotoxicity (CDC) and at

287 The new method includes tissue lysis via pressure cycling technology (PCT) in a Barocyc

288 inkage/fusion of blastomeres with subsequent lysis was 1.71 times higher in the embryos derived from

289 Furthermore, almost complete blood clot lysis was achieved in 75 min, showing considerably highe

290 ells and quantifying proteins released after lysis was designed and 3D-printed.

291 or differences in baseline IOP, laser suture lysis was negatively correlated with low IOP after trabe

292 Consequently, bacterial lysis was observed at 37 degrees C, whilst growth was ma

293 PBP1B lysis was reversed by: (i) reintroducing wild-type uppS,

294 retion, proliferation, and CD8-specific cell lysis) were markedly repressed.

295 NA into the environment through secretion or lysis, which could aid uptake via transformation.

296 fected, produce infectious virus and undergo lysis within 48 h after exposure to low titers (multipli

297 tem secretes proteins which cause phagosomal lysis within the macrophage via an unknown mechanism.

298 ve a single lysis protein that achieves cell lysis without enzymatically degrading the PG.

299 at LtnA1 and LtnA2 can induce rapid membrane lysis without the need for lipid II binding.

300 in our experimental set up, a sector-shaped lysis zone formed.