ライフサイエンスコーパス: lysogeny

1 standing puzzle concerning the regulation of lysogeny.

2 nt site and integrase necessary to establish lysogeny.

3 ng screening of four strains of B. avium for lysogeny.

4 d - these behaviours correspond to lysis and lysogeny.

5 s of elements involved in the maintenance of lysogeny.

6 ro, of bacteriophage 434 that regulate lysis/lysogeny.

7 t gene as seen by the increased frequency of lysogeny.

8 ring lambda infection strongly biases toward lysogeny.

9 n, to commit to a decision between lysis and lysogeny.

10 nd coordinate the decision between lysis and lysogeny.

11 ng their expression, a process called active lysogeny.

12 AimR, reducing aimX expression and promoting lysogeny.

13 e lytic state, preventing conversion back to lysogeny.

14 to the transcription factor, AimR, promoting lysogeny.

15 focus on either obligate lysis or persistent lysogeny.

16 finities to achieve both wild type lysis and lysogeny.

17 ress transcription of CI from pRM to prevent lysogeny.

18 tes bacterial survival and enables efficient lysogeny.

19 ively higher concentrations avoids restoring lysogeny.

20 t-encoded LexA protein to maintain CTXvarphi lysogeny.

21 ssential for lytic growth and does not alter lysogeny.

22 uction of that for loop breakdown stabilizes lysogeny.

23 acquisition of novel genes, a process called lysogeny.

24 alitatively different behaviours - lysis and lysogeny.

25 by all viruses leads to the establishment of lysogeny.

26 4- to 5-fold decrease in the probability of lysogeny.

27 sferase is essential for maintenance of 933W lysogeny.

28 centers, but it lacked any obvious genes for lysogeny.

29 sis for the establishment and maintenance of lysogeny.

30 in the lysogens and was necessary for stable lysogeny.

31 s associated with more successful and stable lysogeny.

32 Xphi integration and the factors that govern lysogeny.

33 s and is important for stable maintenance of lysogeny.

34 he Stx2-encoding phages were used to examine lysogeny.

35 onsible for maintaining CI expression during lysogeny.

36 erD, and the recombination sites involved in lysogeny.

37 l for establishment and maintenance of phage lysogeny.

38 us may be regulated by processes that govern lysogeny.

39 ns that mediate these processes often invoke lysogeny(3-6), a latent infection strategy used by tempe

40 the expression of the negative regulator of lysogeny, AimX, by binding to the transcription factor,

41 g lysis from sequence diversification during lysogeny, allowing rapid adaptation of phage populations

42 We also readdress the prevalence of lysogeny among marine bacteria by probing a collection o

43 model systems to examine the consequences of lysogeny among several dominant marine bacterial lineage

44 e family, with the lack of toxin, virulence, lysogeny and antibiotic resistance genes.

45 acteriophage with different probabilities of lysogeny and different spontaneous induction rates.

46 ies, including dissociation between rates of lysogeny and FCIC values.

47 These data suggest that maintenance of lysogeny and genome wide stabilisation of mobile element

48 , bacteriophage with higher probabilities of lysogeny and higher induction rates are favored.

49 While the molecular mechanisms underlying lysogeny and induction in bacteriophage have been intens

50 ls), bacteriophage with low probabilities of lysogeny and low induction rates can always invade when

51 re, factors that regulate the switch between lysogeny and lytic growth, e.g., repressor, operator sit

52 g debate over the ecological significance of lysogeny and other viral life strategies in nature(6,8-1

53 However, acrIIA23 is not transcribed during lysogeny and phage integration/excision cycles can resul

54 , as a tool for investigating the effects of lysogeny and phage resistance on virulence.

55 strengthens repression of lytic genes during lysogeny and simultaneously ensures efficient switching

56 ctions including genetic coexistence through lysogeny, and phages directly modulate microbiota compos

57 Sequence motifs required for lysogeny are detectable in other metagenomically defined

58 Most examples of adaptations caused by phage lysogeny are through the acquisition of new genes.

59 ergic status yield a bimodal distribution of lysogeny as a function of microbial densities.

60 n that contrasts with the prevailing view of lysogeny as a low-density refugium strategy.

61 ons should select for plasticity in entering lysogeny as well as virus reactivation once signal conce

62 herefore eliminated transductant killing and lysogeny, as did inclusion of citrate and the use of a l

63 cision-lysis upon single-phage infection and lysogeny at higher MOI.

64 this strategy by increasing the frequency of lysogeny at higher multiplicity of infection (MOI).

65 d dynamics was explored in two growth media, lysogeny broth (LB) and tryptic soy broth (TSB).

66 pe and isogenic Deltahns strains cultured in lysogeny broth (LB) in the presence or absence of HSA re

67 nt levels, comparable to 10,000-fold diluted lysogeny broth (LB), are sufficient to sustain this grow

68 control group (n = 11) we instilled sterile lysogeny broth endobronchially.

69 ine studies of Escherichia coli K12 grown in lysogeny broth medium and particularly focused on the si

70 Lysogeny Broth medium samples reconstituted in MeOH/H2O

71 differences in metabolism in cells grown on lysogeny broth or artificial sputum medium.

72 unction of phi3T_93, a protein that promotes lysogeny by binding to MazE and releasing MazF.

73 ions in the establishment and maintenance of lysogeny by binding to Mu operator DNA to shut down tran

74 strategy used by arbitrium to control lysis-lysogeny by domesticating and fine-tuning a phage-defenc

75 In this study, we examined the effect of lysogeny by PhiCD119 on C. difficile toxin production.

76 f bacteriophage Mu establishes and maintains lysogeny by shutting down transposition functions needed

77 f bacteriophage Mu establishes and maintains lysogeny by shutting down transposition functions needed

78 It has been hypothesized that lysogeny can destabilize microbiomes, but lysogeny has n

79 Here, we show that active lysogeny can fuel rapid, parallel adaptations in establi

80 at infection delays lower the probability of lysogeny compared to simultaneous infections.

81 are significantly enhanced in cells entering lysogeny compared to those undergoing lysis.

82 Because lysogeny confers immunity to infection by related viruse

83 ngoing development of the phage lambda lysis-lysogeny decision as a model system to investigate all a

84 ion is analyzed using the phage lambda lysis-lysogeny decision circuit as a model system.

85 teriophage 434 repressor to govern the lysis-lysogeny decision depends on the DNA binding activities

86 lank the immunity region; possibly the lysis-lysogeny decision is more variable among isolates.

87 uilding from this analysis, the lambda lysis-lysogeny decision now serves as a paradigm for how intri

88 ndividual phage infections affects the lysis-lysogeny decision of bacteriophage lambda despite variab

89 oise has been implicated in the random lysis/lysogeny decision of bacteriophage-lambda, in the loss o

90 llular ionic environment influence the lysis-lysogeny decision of the bacteriophage lambda(imm434).

91 ght forward two new players in the SPB lysis-lysogeny decision system, YopN and the phage repressor Y

92 s into the molecular mechanisms behind lysis-lysogeny decision-making in Gram-positive phages.

93 e MOI from replicated viral DNA during lysis-lysogeny decision-making is unclear.

94 host cell density information into the lysis-lysogeny decision.

95 e temperate phages use to inform their lysis-lysogeny decision.

96 m, termed arbitrium, to coordinate the lysis-lysogeny decision.

97 tion of genes that determine the phage lysis-lysogeny decision.

98 ication arbitrium system to coordinate lysis-lysogeny decisions, but the underlying mechanism remains

99 the strategies used by phages to make lysis-lysogeny decisions, we can improve our understanding of

100 tem, termed "arbitrium," to coordinate lysis-lysogeny decisions.

101 arbitrium SPbeta-like phages in making lysis-lysogeny decisions.

102 res indicate that RpoS regulates phage lysis-lysogeny decisions.

103 te host-derived information into their lysis-lysogeny decisions.

104 use a novel strategy in regulating its lysis-lysogeny decisions.

105 a modular format, which includes modules for lysogeny, DNA replication, DNA packaging, structural pro

106 F, forms the repression module necessary for lysogeny establishment and maintenance.

107 formula that approximates the probability of lysogeny for variable infection times by a time-weighted

108 We found that lysogeny had no effect on any of the in vivo or in vitro

109 at lysogeny can destabilize microbiomes, but lysogeny has no direct analog in classical ecological th

110 a-phage interaction with condition-dependent lysogeny highly complex.

111 he genetic switch mechanism used to regulate lysogeny in bacteriophages.

112 Here, we review the mechanisms regulating lysogeny in complex communities and show that the additi

113 During lysogeny in Listeria, AcrIIA1 triggers Cas9 degradation.

114 ced looping can influence the maintenance of lysogeny in the lambda repressor system; it can encode s

115 Our arguments suggest that the stability of lysogeny in the lambda-phage may be influenced by such e

116 specific recombination strategy to establish lysogeny, in which a double-stranded recombination subst

117 bda phages decreases, and the propensity for lysogeny increases, demonstrating how host physiology in

118 Establishment of lysogeny involves integration of the phage genome into t

119 n game theory: Alternating between lysis and lysogeny is a winning strategy for a bacteriophage, even

120 sulting in horizontal transmission), whereas lysogeny is characterized by the integration of the phag

121 of M. smegmatis, but are downregulated once lysogeny is established by binding of RedRock ParB to pa

122 Fine-tuning of the maintenance of lysogeny is facilitated by interactions between CI dimer

123 It has been argued that lysogeny is favoured in phages at low host densities.

124 on, and show that a choice between lysis and lysogeny is first made at the level of the individual vi

125 tween cell death (lysis) and viral dormancy (lysogeny), is influenced by the relative abundance of vi

126 Lysogeny led to improved adherence to inert surfaces and

127 trate how to overcome these obstacles in the lysogeny maintenance promoter of bacteriophage lambda, P

128 during the establishment and maintenance of lysogeny may explain why most spacers in natural bacteri

129 The lysogeny module of phiSa3ms was shown to have some lambd

130 bp deletion was also identified at the gamma lysogeny module, explaining its shift from a temperate t

131 sequence and overall gene content within the lysogeny module.

132 Here we show that lysogeny occurs in natural populations of an autotrophic

133 Initial findings suggest that lysogeny of B. anthracis promotes ecological adaptation,

134 ntation, capsular polysaccharide production, lysogeny of certain bacteriophages, and proteolytic degr

135 izontally acquired genes, Rho also maintains lysogeny of defective and functional prophages.

136 nd within the region, and we demonstrate the lysogeny of Shigella species with STEC bacteriophages.

137 r CRISPR regions in modifying the effects of lysogeny on P. aeruginosa.

138 identify several variants of both lysis and lysogeny - one wild type and one modified behaviour for

139 IC studies do not provide robust measures of lysogeny or consistent evidence of either positive or ne

140 redicted phage genes are expressed either in lysogeny or in lytic growth, 45% of the predicted genes

141 hat provides the phage with an advantage for lysogeny or lytic growth.

142 ted immunity against viruses reemerging from lysogeny or migration.

143 Though recent hypotheses suggest lysogeny predominates in soil, our evidence indicates th

144 rus and challenges previous predictions that lysogeny prevails as the dominant viral lifestyle in the

145 Examination of cross-plaquing and lysogeny profiles further substantiated that each phage

146 luences host QS while enacting its own lytic-lysogeny program without interference.

147 The lysogeny promoting protein CII from bacteriophage 186 is

148 to optimize the ratio between the lysis and lysogeny propensities rather than the phage burst size i

149 raction of chemically inducible cells (FCIC) lysogeny proxy determined using DNA-damaging mitomycin C

150 at have evolved moderately low induction and lysogeny rates will be able to "hedge their bets" agains

151 es, an N6-DNA adenine methyltransferase, and lysogeny-related genes.

152 he mechanism by which these phages establish lysogeny remains unknown.

153 t the phage life cycle, along with the lysis-lysogeny reporters.

154 es, MazF activity promotes reversion back to lysogeny, since AimX is absent.

155 here provides a new perspective on the lysis/lysogeny switch of bacteriophage lambda.

156 n of the lac operon in E. coli and the lysis/lysogeny switch of phage lambda.

157 hat salt stress can regulate the phage lysis-lysogeny switch.

158 Prophages are phages in lysogeny that are integrated into, and replicated as par

159 During lysogeny, the late transcript is prematurely terminated

160 To promote lysogeny, these repressors bind to multiple sites in the

161 Together, our findings thus link lysogeny to human age, geography, and disease, and demon

162 In studied systems, prophage induction from lysogeny to lysis is near-universally driven by DNA-dama

163 ms of a 'hair-trigger' molecular switch from lysogeny to lysis.

164 tein levels are critical for the switch from lysogeny to lytic growth.

165 work offers the first formal theory linking lysogeny to microbiome stability.

166 This epigenetic switch from lysogeny to the lytic state occurs on activation of the

167 VL1 is a virulent phage as no genes encoding lysogeny, toxins or antibiotic resistance were identifie

168 to characterise the physiological impact of lysogeny under antimicrobial pressure.

169 rsity, growth rates, and/or the incidence of lysogeny underlie these trends.

170 Lysogeny was found to occur more commonly than lytic inf

171 Protection through lysogeny was rarely observed because the lysogens have i

172 ia with phage exhibiting condition-dependent lysogeny, where the type of phage infection lifecycle is

173 interaction mediated by condition-dependent lysogeny, where the type of the phage infection cycle (l

174 host interaction: lysis of the host cell and lysogeny whereby the virus genome integrates into the ho

175 lytA indicates the widespread occurrence of lysogeny, which may contribute to genetic variation in n

176 en by the inability to reestablish CTXvarphi lysogeny while RstC is overexpressed.

177 We found that lysogeny with MM1-1998 coincided with a more transparent

178 adherence was independently associated with lysogeny with the MM1-1998 phage.

179 We determine that lysogeny within Escherichia coli biofilms initially occu

180 I) protein-induced DNA loop maintains stable lysogeny, yet allows efficient switching to lysis.